Recent Longevity News for the seven days ending 6/16/10.  You should consult your doctor if you are taking any medications.

HDL Cholesterol and Cancer - Medscape, 6/15/10 - "even after adjustment for multiple variables, there was a 36% lower risk of cancer for every 10-mg/dL increase in HDL cholesterol" - See niacin at Amazon.com.

Replacing white rice with brown rice or other whole grains may reduce diabetes risk - Science Daily, 6/14/10 - "replacing 50 grams of white rice (just one third of a typical daily serving) with the same amount of brown rice would lower risk of type 2 diabetes by 16%. The same replacement with other whole grains, such as whole wheat and barley, was associated with a 36% reduced risk" - See brown rice pasta at Amazon.com.

Popular blood pressure pills linked to cancer - MSNBC, 6/13/10 - "experts found a link between people taking medicines known as angiotensin-receptor blockers ... one extra cancer case will occur for every 105 people taking the medications for about four years ... The maker of the most-used drug in the study ... it had "internal safety data" contradicting the Lancet study. According to studies run by the pharmaceutical, there was no link between increased cancer risk and Micardis ... Scientists aren't sure why ARBs might raise the possibility of developing cancer, though some animal studies suggest the medications help produce new blood vessels, which would speed tumor growth" - Note:  New blood vessels can be a good thing like with heart disease (2) and PAD and increased endurance so it may be sacrificing one thing for another.

Probiotics may help fat and weight loss: Study - Nutra USA, 6/11/10 - "Twelve weeks of consuming a fermented milk product containing the Lactobacillus strain was associated with a 4.6 per cent reduction in abdominal fat, and a 3.3 per cent reduction in subcutaneous fat" - [Abstract]

• See Yogourmet Electric Yogurt Maker - I've had a lot of yogurt makers over the years but this is the best one I've found.  I mix two cups of Nestle Nido Instant Dry Whole Milk (available at Amazon) with two cups of dry skim milk in a blender.  Lately I've been making it with Activa. I believe it's only sold flavored but I've been using the strawberry flavored Activa.  I put the milk powders in a blender then fill it with water and blend.  Then add one container of the Activa and blend fast one more time (not to kill the culture).  Then pour it into the jar and fill the jar to the top with additional water and leave it in the yoghurt maker for 13 hours.  I mix the finished product with Smucker's Strawberry Orchard's Finest.  If your worried about the BPA's from the plastic container, see Widemouth Clear Half Gallon Glass Jar (64oz) w/ White Metal Lid  at specialtybottles.com.
• Activia by Dannon - "Specialists at Dannon® selected Bifidus Regularis™ for Activia® because it survives passage through the digestive tract, arriving in the colon as a living culture. Once there, it plays a beneficial role in your intestinal ecosystem"

• Implies that bad bacteria in the gut may be the cause of colon cancer:  Bacteria as a predicter of colorectal cancer - Science Daily, 5/25/10 - "Several bacterial signatures were detected only in subjects with polyps, others only in subjects without polyps. Eubacterium ramulus was increased in the stools of subjects with polyps while Ruminococcus sp and a human intestine firmicute were increased in subjects without polyps. In tissue samples, Acidovorax sp. was found more frequently in subjects with polyps. Other bacterial signatures that differed between cases and controls were observed but did not match any know bacteria, suggesting unidentified and uncharacterized bacteria are also present"

Vitamin D Exposure in Childhood Linked to Age at Onset of MS - Medscape, 6/10/10 - "For those living in low– to medium–solar radiation areas, the researchers found a significant association between earlier age at onset of symptoms and sun exposure in the fall/winter season between the ages of 6 and 15 years (2.3 years average earlier onset; P = .01). Intake of cod liver oil during childhood produced a 3-year delay in onset"

Polyphenols in red wine and green tea halt prostate cancer growth, study suggests - Science Daily, 6/9/10 - "The profound impact that the antioxidants in red wine and green tea have on our bodies is more than anyone would have dreamt just 25 years ago," Weissmann added. "As long as they are taken in moderation, all signs show that red wine and green tea may be ranked among the most potent 'health foods' we know." - See resveratrol products at Amazon.com and green tea extract at Amazon.com.

Most cans of food contain controversial BPA - MSNBC, 6/9/10 - "BPA, or bisphenol A, is ubiquitous. Simply put, just about anything you eat that comes out of a can — from Campbell's Chicken Soup and SpaghettiOs to Diet Coke and BumbleBee Tuna — contains the same exact chemical ... The exposure to BPA from canned food "is far more extensive" than from plastic bottles, said Shanna Swan, a professor and researcher at the University of Rochester in New York. "It's particularly concerning when it's lining infant formula cans.""

Link between depression, abdominal obesity confirmed by new study - Science Daily, 6/9/10 - "cortisol, a stress hormone, is related to depression and abdominal obesity. "So, there is reason to suspect that people who are depressed would have higher levels of abdominal obesity versus other parts of the body because of elevated cortisol,""

Telomeres: Size matters when it comes to DNA - Science Daily, 6/9/10 - "Telomere shortening can be reversed in two specific ways: ... a protein termed telomerase can directly add new DNA to the end of telomeres ... The second method is much less understood but most likely involves the copying of information from one telomere to another"

New evidence that drinking coffee may reduce the risk of diabetes - Science Daily, 6/9/10 - "The scientists fed either water or coffee to a group of laboratory mice commonly used to study diabetes. Coffee consumption prevented the development of high-blood sugar and also improved insulin sensitivity in the mice, thereby reducing the risk of diabetes. Coffee also caused a cascade of other beneficial changes in the fatty liver and inflammatory adipocytokines related to a reduced diabetes risk. Additional lab studies showed that caffeine may be "one of the most effective anti-diabetic compounds in coffee,""

Abstracts from this week's Doctor's Guide Nutrition/Dietetics plus abstracts from my RSS feeds (Click here for the journals, the PubMed ones at the top):

Do high ferritin levels confer lower cardiovascular risk in men with Type 2 diabetes? - Diabet Med. 2010 Apr;27(4):417-22 - "were divided according to ferritin quartiles (Q) as follows: QI-III, normal ferritin (NF; n = 318), mean +/- 1 sd ferritin 133 +/- 72 ng/ml; and QIV patients, high ferritin (HF; n = 106), ferritin 480 +/- 228 ng/ml ... the prevalence of macroangiopathy was unexpectedly much lower in patients with high ferritin, as follows: 25% vs. 43% for overall macroangiopathy; 7% vs. 16% for peripheral artery disease; and 16% vs. 31% for coronary artery disease (P = 0.0009, P = 0.0140 and P = 0.0035, respectively, vs. NF patients). Insulin resistance index and prevalence of liver steatosis were higher in HF compared with NF patients as follows: 2.17% vs. 1.89% and 78% vs. 64% (P = 0.0345 and P = 0.0059, respectively). Liver enzymes (aspartate aminotransferase, alanine aminotransferase and gamma-glutamyl transferase) were significantly higher in HF, by 33%, 42% and 72%, respectively (all P < 0.0002), suggesting a higher prevalence of steatohepatitis ... Our results demonstrate that T2DM males with high ferritin levels exhibit a markedly decreased prevalence of macroangiopathy, despite more severe insulin resistance and higher markers of steatohepatitis. High ferritin levels and/or steatosis may thus paradoxically confer a lowered cardiovascular risk in diabetic males" - See Slow Fe Slow Release Iron Tablets 90-Count Box at Amazon.com.

Reduction of Prostate-specific Antigen After Tamsulosin Treatment in Patients With Elevated Prostate-specific Antigen and Lower Urinary Tract Symptoms Associated With Low Incidence of Prostate Cancer at Biopsy - Urology. 2010 Jun 8 - "A total of 80 patients completed the present study. The mean patient age was 66.3 years, and the mean PSA level was 7.8 +/- 8.4 ng/mL at baseline and 7.1 +/- 9.1 ng/mL after treatment (P < .001). A total of 29 patients (36.25%) were diagnosed with prostate cancer from the biopsy findings. A significant increment in the PSA level was observed in patients with prostate cancer (6.7 versus 7.9 ng/mL; P = .002). A significant decrease in the PSA level was observed in patients with negative biopsy findings (6.9 versus 5.1 ng/mL, P = .000). Of the 38 patients with a decrease in the PSA level, 1 (2.6%) was diagnosed with prostate cancer and 37 (97.4%) with an benign prostatic hyperplasia/prostatitis. Of the 42 patients with no change in the PSA level, 28 (66.7%) had prostate cancer and 14 (33.3%) had negative findings. A change in PSA level after treatment gave a sensitivity of 96.6%, specificity of 72.5%, and diagnostic accuracy of 81% for prostate cancer. CONCLUSIONS: Treatment with tamsulosin seemed to reduce the PSA levels and identified patients at high risk of prostate cancer" - Note: Tamsulosin is Flomax.

Vitamin D deficiency and frailty in older Americans - J Intern Med. 2010 Apr 28 - "Nationally representative survey of noninstitutionalized US residents collected between 1988 and 1994. Results. 25-Hydroxyvitamin D deficiency, defined as a serum concentration <15 ng mL(-1), was associated with a 3.7-fold increase in the odds of frailty amongst whites and a fourfold increase in the odds of frailty amongst non-whites. This association persisted after sensitivity analyses adjusting for season of the year and latitude of residence, intended to reduce misclassification of persons as 25-hydroxyvitamin D deficient or insufficient. Conclusion. Low serum 25-hydroxyvitamin D concentrations are associated with frailty amongst older adults" - See vitamin D at Amazon.com.

During testosterone administration, total and free E2 levels increased dose-dependently (dose effect, P < 0.001) in both young and older men - J Clin Endocrinol Metab. 2010 Jun 9 - "During testosterone administration, total and free E2 levels increased dose-dependently (dose effect, P < 0.001) in both young and older men" - From a previous newsletter:

• Sex Hormones and the Risk of Incident Prostate Cancer - Urology. 2010 May 6 - "Serum testosterone, estradiol, estrone, and sex hormone-binding globulin were assayed at baseline ... the mean age was 73 years. Higher serum estrone was strongly related to an increased risk of prostate cancer: compared with men in the lower quartile, the risk of prostate cancer among those in the highest 3 quartiles (>24.9 pg/dL) was nearly 4-fold higher (adjusted heart rate = 3.93, CI: 1.61-9.57). Other sex hormones were not associated with the risk of prostate cancer" - The following results for estrone are for women.   I didn't find any results for men but see the "For Aromatization (in males):" section on my letrozole page.
  • Letrozole suppresses plasma estradiol and estrone sulphate more completely than anastrozole in postmenopausal women with breast cancer - J Clin Oncol. 2008 Apr 1;26(10):1671-6 - "Letrozole reduces plasma E2 and E1S levels to a significantly greater extent than anastrozole" - See Femara (letrozole)at OffshoreRX.
  • Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study - J Clin Oncol. 2002 Feb 1;20(3):751-7 - "estrone (E(1)), estradiol (E(2)), and estrone sulfate (E(1)S) ... Treatment with anastrozole suppressed plasma levels of E(1), E(2), and E(1)S by a mean of 81.0%, 84.9%, and 93.5%, respectively, whereas treatment with letrozole caused a corresponding decrease of 84.3%, 87.8% and 98.0%, respectively. The suppression of E(1) and E(1)S was found to be significantly better during treatment with letrozole compared with anastrozole"

Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial - Eur J Clin Nutr. 2010 Jun;64(6):636-43 - "fermented milk (FM) ... In the active FM group, abdominal visceral and subcutaneous fat areas significantly (P<0.01) decreased from baseline by an average of 4.6% (mean (confidence interval): -5.8 (-10.0, -1.7) cm(2)) and 3.3% (-7.4 (-11.6, -3.1) cm(2)), respectively. Body weight and other measures also decreased significantly (P<0.001) as follows: body weight, 1.4% (-1.1 (-1.5, -0.7) kg); BMI, 1.5% (-0.4 (-0.5, -0.2) kg/m(2)); waist, 1.8% (-1.7 (-2.1, -1.4) cm); hip, 1.5% (-1.5 (-1.8, -1.1) cm). In the control group, by contrast, none of these parameters decreased significantly. High-molecular weight adiponectin in serum increased significantly (P<0.01) in the active and control groups by 12.7% (0.17 (0.07, 0.26) microg/ml) and 13.6% (0.23 (0.07, 0.38) microg/ml), respectively. CONCLUSION: The probiotic LG2055 showed lowering effects on abdominal adiposity, body weight and other measures, suggesting its beneficial influence on metabolic disorders"

Calorie restriction: what recent results suggest for the future of ageing research - Eur J Clin Invest. 2010 May;40(5):440-50 - "the search for substances that can reproduce the beneficial physiologic responses of CR without a requisite calorie intake reduction, termed CR mimetics (CRMs), has gained momentum. Material and methods Recent articles describing health and lifespan results of CR in nonhuman primates and short-term human studies are discussed. Additional consideration is given to the rapidly expanding search for CRMs. Results The first results from a long-term, randomized, controlled CR study in nonhuman primates showing statistically significant benefits on longevity have now been reported. Additionally, positive results from short-term, randomized, controlled CR studies in humans are suggestive of potential health and longevity gains, while test of proposed CRMs (including rapamycin, resveratrol, 2-deoxyglucose and metformin) have shown both positive and mixed results in rodents"

Consumption of omega-3 fatty acids and fish and risk of age-related hearing loss - Am J Clin Nutr. 2010 Jun 9 - "There was an inverse association between total n-3 PUFA intake and prevalent hearing loss [odds ratio (OR) per SD increase in energy-adjusted n-3 PUFAs: 0.89; 95% CI: 0.81, 0.99]. There was an inverse association between long-chain n-3 PUFAs and incident hearing loss (OR per SD increase in long-chain n-3 PUFAs: 0.76; 95% CI: 0.60, 0.97). Participants who had >/=2 servings of fish/wk compared with participants who had <1 serving of fish/wk had a significantly reduced risk (42%) of developing presbycusis at follow-up (multivariate-adjusted OR: 0.58; 95% CI: 0.35, 0.95). There was an association between consumption of >/=1 to <2 servings/wk of fish and a reduced risk of a progression of hearing loss (OR: 0.53; 95% CI: 0.32, 0.88). CONCLUSIONS: There was an inverse association between higher intakes of long-chain n-3 PUFAs and regular weekly consumption of fish and hearing loss. Dietary intervention with n-3 PUFAs could prevent or delay the development of age-related hearing loss" - [Nutra USA] - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.

Blood concentration of methylmercury in relation to food consumption - Public Health Nutr. 2010 Jun 8:1-10 - "Mean (range) blood MeHg concentration was 4.6 (0.21-22) mug/l among men and 2.8 (<0.15-20) mug/l among women. Fish had the strongest positive association with MeHg (P for linear trend <0.001 among both men and women). Among men, positive associations were also observed for fruit vegetables, wheat and wine. Among women, positive associations were observed for root vegetables, legumes, potato and game, but adjustment for fish consumption attenuated these trends. CONCLUSIONS: The study shows that, besides fish, MeHg may have other dietary sources that should be taken into account in risk assessment studies" - Note:  It's something to think about if you're worried about the mercury in the flu vaccine, you're getting mercury in just about everything else also.

Differences in antioxidant levels of fresh, frozen and freeze-dried strawberries and strawberry jam - Int J Food Sci Nutr. 2010 Jun 9 - "total antioxidant activity (TAA) ... The mean TAA for freeze-dried strawberries based on an 'as consumed' weight (95% confidence interval [CI]: 29.58, 30.58) was significantly higher than for fresh (95% CI: 3.18, 3.66), frozen (95% CI: 2.58, 2.79), and jam (95% CI: 1.10, 1.22). The mean TAA based on dry weight for fresh strawberries (95% CI: 40.48, 46.67) was significantly higher than for freeze-dried (95% CI: 29.58, 30.58), frozen (95% CI: 24.62, 26.59), and jam (95% CI: 1.48, 1.64). Results agree with previous studies reporting that strawberries are a valuable source of antioxidants for consumers"

Phosphatidylserine Containing omega-3 Fatty Acids May Improve Memory Abilities in Non-Demented Elderly with Memory Complaints: A Double-Blind Placebo-Controlled Trial - Dement Geriatr Cogn Disord. 2010 Jun 3;29(5):467-474 - "The results indicate that PS-DHA may improve cognitive performance in non-demented elderly with memory complaints. Post-hoc analysis of subgroups suggests that participants with higher baseline cognitive status were most likely to respond to PS-DHA" - See Jarrow Max DHA at Amazon.comand phosphatidylserine products at iHerb.

Health Focus (Breast Cancer):

Popular Medications:

• Arimidex (anastrozole) / Aromasin (exemestane) / Femara (letrozole) / Nolvadex (tamoxifen) / Faslodex (fulvestrant)
• Avastin (bevacizumab) / Xeloda (capecitabine) / Herceptin (trastuzumab) / Taxol (paclitaxel) / Taxotere (docetaxel) / Aptosyn (exisulind) / Evista (raloxifene) / Doxil® (doxorubicin HCl)

Popular Supplements:

• See Cancer Cures?

Alternative News:

• Breast Cancer - Life Extension Magazine
• Breast Cancer and Nutritional Supplements - natmedonline.com
• I have seen advertisements for a supplement containing calcium D-glucarate to prevent breast cancer. How does this product work? - Dr. Murray
• Beating Breast Cancer - thenutritionreporter.com
• Causes of Breast Cancer - thenutritionreporter.com
• Using Nutrients for Gene Therapy - thenutritionreporter.com
• Different Types of Dietary Fat - thenutritionreporter.com
• Non-steroidal anti-inflammatory drug (NSAID) use and breast cancer risk in the Western New York Exposures and Breast Cancer (WEB) Study - Cancer Causes Control. 2010 May 25 - "Recent aspirin use was inversely associated with breast cancer risk (adjusted OR 0.80, 95% CI: 0.68-0.94); the strongest reduction in risk was observed among those who took >/=2 pills/day on days that aspirin was taken (OR 0.74, 95% CI: 0.61-0. 90). Adult lifetime use was also associated with breast cancer risk (>10 days/month, adjusted OR 0.68, 95% CI: 0.46-1.00). Use of ibuprofen or acetaminophen was not associated with breast cancer"
• Broccoli component limits breast cancer stem cells, study finds - Science Daily, 5/4/10 - "In the current study, researchers took mice with breast cancer and injected varying concentrations of sulforaphane from the broccoli extract. Researchers then used several established methods to assess the number of cancer stem cells in the tumors. These measures showed a marked decrease in the cancer stem cell population after treatment with sulforaphane, with little effect on the normal cells. Further, cancer cells from mice treated with sulforaphane were unable to generate new tumors. The researchers then tested sulforaphane on human breast cancer cell cultures in the lab, finding similar decreases in the cancer stem cells" - See sulforaphane at Amazon.com.
• Vitamin and calcium supplements may reduce breast cancer risk - Science Daily, 4/18/10 - "It is not an immediate effect. You don't take a vitamin today and your breast cancer risk is reduced tomorrow ... Vitamin supplements appeared to reduce the risk of breast cancer by about 30 percent"
• Experts allay fears over multivitamins and breast cancer risk - Nutra USA, 4/7/10
• Bitter melon extract decreased breast cancer cell growth - Science Daily, 2/23/10 - "Bitter melon extract, a common dietary supplement, exerts a significant effect against breast cancer cell growth and may eventually become a chemopreventive agent against this form of cancer ... the mechanism of bitter melon extract significantly decreased proliferation, that is, cell growth and division, and induced death in breast cancer cells" - See bitter melon extract at Amazon.com.
• Aspirin Intake and Survival After Breast Cancer - J Clin Oncol. 2010 Feb 16 - "Aspirin use was associated with a decreased risk of breast cancer death. The adjusted relative risks (RRs) for 1, 2 to 5, and 6 to 7 days of aspirin use per week compared with no use were 1.07 (95% CI, 0.70 to 1.63), 0.29 (95% CI, 0.16 to 0.52), and 0.36 (95% CI, 0.24 to 0.54), respectively (test for linear trend, P < .001). This association did not differ appreciably by stage, menopausal status, body mass index, or estrogen receptor status. Results were similar for distant recurrence. The adjusted RRs were 0.91 (95% CI, 0.62 to 1.33), 0.40 (95% CI, 0.24 to 0.65), and 0.57 (95% CI, 0.39 to 0.82; test for trend, P = .03) for 1, 2 to 5, and 6 to 7 days of aspirin use, respectively. CONCLUSION: Among women living at least 1 year after a breast cancer diagnosis, aspirin use was associated with a decreased risk of distant recurrence and breast cancer death"
• DHA omega-3 may improve chemotherapy outcomes: Study - Nutra USA, 2/10/10 - "Our data show for the first time that a dietary intervention targeted on DHA is a feasible approach that has potential to substantially increase survival in metastatic breast cancer patients treated with chemotherapy ... the overall survival of women was 22 months, and reached 34 months in women with the highest DHA levels in their blood" - [Abstract] - See Jarrow Max DHA at Amazon.com.
• Improving outcome of chemotherapy of metastatic breast cancer by docosahexaenoic acid: a phase II trial - Br J Cancer. 2009 Dec 15;101(12):1978-85 - "The objective response rate was 44%. With a mean follow-up time of 31 months (range 2-96 months), the median TTP was 6 months. Median OS was 22 months and reached 34 months in the sub-population of patients (n = 12) with the highest plasma DHA incorporation. The most common grade 3 or 4 toxicity was neutropaenia (80%). CONCLUSION: DHA during chemotherapy was devoid of adverse side effects and can improve the outcome of chemotherapy when highly incorporated. DHA has a potential to specifically chemosensitise tumours" - See Jarrow Max DHA at Amazon.com.
• Carotenoids may reduce breast cancer risk in women: Study - Nutra USA, 2/8/10 - "The highest average levels of alpha- and beta-carotene were associated with a 68 and 65 per cent reduction in the risk of ER-PR breast cancer among smokers" - [Abstract] - See Jarrow Formulas, CarotenALL, Mixed Carotenoid Complex at Amazon.com.
• Moderate physical activity and breast cancer risk: the effect of menopausal status - Cancer Causes Control. 2010 Jan 19 - "Participating in moderate-intensity physical activity decreased the risk of BC in both pre- and postmenopausal women (OR = 0.96; 95% CI 0.92.-0.99; OR = 0.90; 95% CI 0.86-0.93, respectively) for every 3 h per week of moderate-intensity physical activity. There was a statistically significant modification effect by menopausal status"
• Pomegranates May Stall Breast Cancer - WebMD, 1/5/10 - "Eating pomegranates or drinking pomegranate juice may help prevent and slow the growth of some types of breast cancer ... Researchers say the ellagitannins in pomegranates work by inhibiting aromatase, which is a key enzyme used by the body to make estrogen and plays a key role in breast cancer growth" - See pomegranate at Amazon.com.
• Soy food intake and breast cancer survival - JAMA. 2009 Dec 9;302(22):2437-43 - "Soy food intake, as measured by either soy protein or soy isoflavone intake, was inversely associated with mortality and recurrence. The hazard ratio associated with the highest quartile of soy protein intake was 0.71 (95% confidence interval [CI], 0.54-0.92) for total mortality and 0.68 (95% CI, 0.54-0.87) for recurrence compared with the lowest quartile of intake. The multivariate-adjusted 4-year mortality rates were 10.3% and 7.4%, and the 4-year recurrence rates were 11.2% and 8.0%, respectively, for women in the lowest and highest quartiles of soy protein intake. The inverse association was evident among women with either estrogen receptor-positive or -negative breast cancer and was present in both users and nonusers of tamoxifen. CONCLUSION: Among women with breast cancer, soy food consumption was significantly associated with decreased risk of death and recurrence"
• Spices may boost breast health: Study - Nutra USA, 12/9/09 - "curcumin, found in turmeric, and piperine, found in black peppers, decreased the number of stem cells while having no effect on normal differentiated cells ... If we can limit the number of stem cells, we can limit the number of cells with potential to form tumours ... normal, non-cancerous stem cells were unaffected by the compounds, which appeared to selectively target the cancer stem cells" - [Abstract] - See curcumin products at Amazon.com and piperine extract at Amazon.com.
• Targeting breast stem cells with the cancer preventive compounds curcumin and piperine - Breast Cancer Res Treat. 2009 Nov 7 - "Both curcumin and piperine inhibited mammosphere formation, serial passaging, and percent of ALDH+ cells by 50% at 5 muM and completely at 10 muM concentration in normal and malignant breast cells. There was no effect on cellular differentiation. Wnt signaling was inhibited by both curcumin and piperine by 50% at 5 muM and completely at 10 muM. Curcumin and piperine separately, and in combination, inhibit breast stem cell self-renewal but do not cause toxicity to differentiated cells. These compounds could be potential cancer preventive agents. Mammosphere formation assays may be a quantifiable biomarker to assess cancer preventive agent efficacy and Wnt signaling assessment can be a mechanistic biomarker for use in human clinical trials" - See curcumin products at Amazon.com and piperine extract at Amazon.com.
• Soy Appears Safe for Breast Cancer Survivors - WebMD, 12/8/09
• Resveratrol Modulates Tumor Cell Proliferation and Protein Translation via SIRT1-Dependent AMPK Activation - J Agric Food Chem. 2009 Nov 20 - "Similar to those effects associated with caloric restriction (CR), resveratrol has multiple beneficial activities, such as increased life span and delay in the onset of diseases associated with aging ... Here, we show that resveratrol activated AMPK in both ER-positive and ER-negative breast cancer cells ... Here, we show that resveratrol activated AMPK in both ER-positive and ER-negative breast cancer cells. Once activated, AMPK inhibited 4E-BP1 signaling and mRNA translation via mammalian target of rapamycin (mTOR). Moreover, we also found that AMPK activity mediated by resveratrol in cancer cells was due to inducing the expression of Sirtuin type 1 (SIRT1) via elevation in the cellular NAD(+)/NADH in ER-positive cells. To our knowledge, we demonstrate here for the first time that resveratrol induces the expression of SIRT1 protein in human cancer cells. These observations raise the possibility that SIRT1 functions as a novel upstream regulator for AMPK signaling and may additionally modulate tumor cell proliferation. Targeting SIRT1/AMPK signaling by resveratrol may have potential therapeutic implications for cancer and age-related diseases" - See resveratrol products at Amazon.com.
• High Fiber Intake Linked to Reduced Risk of Breast Cancer - Science Daily, 10/2/09 - "Relative to the lowest quintile of total fiber intake, the highest quintile was associated with a 13% decreased risk of breast cancer"
• Recent, Vigorous Exercise Is Associated With Reduced Breast Cancer Risk - Science Daily, 10/1/09
• Diabetes Drug Fights Breast Cancer - WebMD, 9/14/09 - "And in mice carrying human breast cancers, metformin made standard chemotherapy vastly more effective. Mice treated with the combination remain cancer-free for four months, unlike mice treated with either drug alone ... A lot of data shows lower cancer risk -- not just breast cancer -- in people taking metformin for diabetes ... This drug at low doses can be considered a very good candidate for cancer prevention before a person has any cancer at all" - Note:  I've been taking metformin for years for anti-aging.  See my Insulin and Aging page.  See metformin at IAS.
• The Way You Eat May Affect Your Risk For Breast Cancer - Science Daily, 8/4/09
• Curcumin delays development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz[a]anthracene-induced mammary tumors - Menopause. 2009 Jul 22 - "Combined hormone therapy (HT) containing estrogen and progestin (medroxyprogesterone acetate [MPA]) leads to increased risk of breast cancer in postmenopausal women, compared with HT regimens containing estrogen alone or placebo ... Treatment with curcumin delayed the first appearance of MPA-accelerated tumors by 7 days, decreased tumor incidence by the end of the experiment, and reduced tumor multiplicity in DMBA-induced MPA-accelerated tumors. Curcumin also prevented many of the gross histological changes seen in the MPA-treated mammary gland. Immunohistochemical analyses of mammary tumors showed that curcumin decreased MPA-induced VEGF induction in hyperplastic lesions, although it did not affect the levels of estrogen and progesterone receptors" - See curcumin products at Amazon.com.
• Asian Spice Could Reduce Breast Cancer Risk In Women Exposed To Hormone Replacement Therapy - Science Daily, 7/13/09 - "curcumin, a popular Indian spice derived from the turmeric root, could reduce the cancer risk for women after exposure to hormone replacement therapy ... curcumin delayed the first appearance, decreased incidence and reduced multiplicity of progestin-accelerated tumors in an animal model. Curcumin also prevented the appearance of gross morphological abnormalities in the mammary glands" - See curcumin products at Amazon.com.
• Fatty fish and fish omega-3 fatty acid intakes decrease the breast cancer risk: a case-control study - BMC Cancer. 2009 Jun 30;9(1):216 - "Using a multivariate logistic regression model, high intake of fatty fish was associated with a reduced risk for breast cancer in both pre- and postmenopausal women (OR [95% CI] for highest vs. lowest intake quartiles, p for trend: 0.19 [0.08 to 0.45], p < 0.001 for premenopausal women, 0.27 [0.11 to 0.66], p = 0.005 for postmenopausal women). Similarly, reductions in breast cancer risk were observed among postmenopausal subjects who consumed more than 0.101 g of EPA (OR [95% CI]: 0.38 [0.15 to 0.96]) and 0.213 g of DHA (OR [95% CI]: 0.32 [0.13 to 0.82]) from fish per day compared to the reference group who consumed less than 0.014 g of EPA and 0.037 g of DHA per day. Among premenopausal women, there was a significant reduction in breast cancer risk for the highest intake quartiles of omega-3 fatty acids (ORs [95% CI]: 0.46 [0.22 to 0.96]), compared to the reference group who consumed the lowest quartile of intake" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• Adolescent and adult soy food intake and breast cancer risk: results from the Shanghai Women's Health Study - Am J Clin Nutr. 2009 Jun;89(6):1920-6 - "Adult soy food consumption, measured either by soy protein or isoflavone intake, was inversely associated with the risk of premenopausal breast cancer, and the association was highly statistically significant (P for trend < 0.001). The multivariate-adjusted relative risks (RRs) for the upper intake quintile compared with the lowest quintile were 0.41 (95% CI: 0.25, 0.70) for soy protein intake and 0.44 (95% CI: 0.26, 0.73) for isoflavone intake. High intake of soy foods during adolescence was also associated with a reduced risk of premenopausal breast cancer (RR: 0.57; 95% CI: 0.34, 0.97). Women who consumed a high amount of soy foods consistently during adolescence and adulthood had a substantially reduced risk of breast cancer. No significant association with soy food consumption was found for postmenopausal breast cancer"
• Teen soy intake linked to lower breast cancer risk - Nutra USA, 6/1/09 - "Adolescent intakes of soy foods were associated with a 43 per cent reduction in pre-menopausal breast cancer risk, while high intakes of soy protein and isoflavones were associated with 59 and 56 per cent reductions in the risk of breast cancer before the menopause" - [Abstract]
• Walnuts Fight Breast Cancer - WebMD, 4/21/09 - "Standard testing showed that eating walnuts cut the risk of developing breast tumors in half ... If mice did get breast tumors, the growth rate was also slowed, by 50% ... Extrapolating to humans, this would be about a nine-year delay"
• Relationship between selenium and breast cancer: a case-control study in the Klang Valley - Singapore Med J. 2009 Mar;50(3):265-9 - "Breast cancer risk decreased with the increasing quartiles of selenium intake, with odds ratios (95 percent confidence interval) of 2.95 (1.22-7.12), 2.17 (1.13-4.19) and 1.71 (0.84-3.52), respectively. However, the association diminished after adjustment for confounding factors ... it is essential for Malaysian women to achieve a good selenium status by consuming good food sources of selenium as a chemopreventive agent"
• Dietary carotenoids and the risk of invasive breast cancer - Int J Cancer. 2009 Feb 3 - "An inverse association observed among premenopausal women was for high levels of vitamin A (OR: 0.82, 95% CI: 0.68-0.98, p for trend = 0.01), beta-carotene (OR: 0.81, 95% CI 0.68-0.98, p for trend = 0.009), alpha-carotene (OR: 0.82, 95% CI: 0.68-0.98, p for trend = 0.07) and lutein/zeaxanthin (OR: 0.83, 95% CI 0.68-0.99, p for trend = 0.02). An inverse association was not observed among postmenopausal women. Among premenopausal women who reported ever smoking, these results were stronger than among never smokers, although tests for interaction were not statistically significant. Results from this study are comparable to previous prospective studies, and suggest that a high consumption of carotenoids may reduce the risk of premenopausal but not postmenopausal breast cancer, particularly among smokers" - See Jarrow Formulas, CarotenALL at Amazon.com.
• Early soy intake may slash breast cancer risk later in life - Nutra USA, 3/30/09 - "By comparing the highest and lowest soy intake values for soy-based foods such as tofu, miso and natto, Korde and co-workers calculated that women with the highest soy intake during childhood (ages 5 to 11) had a 58 per cent lower risk of breast cancer as adults as the women with the lowest soy intake as children" - [Abstract]
• Childhood Soy Intake and Breast Cancer Risk in Asian American Women - Cancer Epidemiol Biomarkers Prev. 2009 Mar 24 - "Comparing highest with lowest tertiles, the multivariate relative risks (95% confidence interval) for childhood, adolescent, and adult soy intake were 0.40 (0.18-0.83; Ptrend = 0.03), 0.80 (0.59-1.08; Ptrend = 0.12), and 0.76 (0.56-1.02; Ptrend = 0.04), respectively"
• Extra Virgin Olive Oil May Help To Combat Breast Cancer - Science Daily, 2/5/09 - "this study confirms the potentiality of polyphenols to inhibit HER2 activity and to promote its degradation"
• Glycemic load, glycemic index and breast cancer risk in a prospective cohort of Swedish women - Int J Cancer. 2009 Feb 3 - "In analyses stratified by estrogen receptor (ER) and progesterone receptor (PR) status of the breast tumors, we observed statistically significant positive associations of carbohydrate intake, glycemic index and glycemic load with risk of ER+/PR- breast cancer; the multivariate relative risks comparing extreme quintiles were 1.34 [95% confidence interval (CI) = 0.93-1.94; p for trend = 0.04] for carbohydrate intake, 1.44 (95% CI = 1.06-1.97; p for trend = 0.01) for glycemic index and 1.81 (95% CI = 1.29-2.53; p for trend = 0.0008) for glycemic load. No associations were observed for ER+/PR+ or ER-/PR- breast tumors. These findings suggest that a high carbohydrate intake and diets with high glycemic index and glycemic load may increase the risk of developing ER+/PR- breast cancer"
• Vitamin D Found To Stimulate A Protein That Inhibits The Growth Of Breast Cancer Cells - Science Daily, 2/5/09 - "Calcitrol, the active form of vitamin D, has been found to induce a tumor suppressing protein that can inhibit the growth of breast cancer cells" - See vitamin D at Amazon.com.
• Indole-3-carbinol inhibits MDA-MB-231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activity - Int J Cancer. 2008 Dec 15 - "Using chemotaxis and fluorescent-bead cell motility assays, we demonstrated that I3C significantly decreased the in vitro migration of MDA-MB-231 cells, a highly invasive breast cancer cell line" - See indole-3-carbinol at Amazon.com.
• Green tea may protect against breast cancer: Study - Science Daily, 1/27/09 - "Regular consumption of the beverage was associated with a “slightly decreased risk for breast cancer” of 12 per cent" - [Abstract] - See green tea extract at Amazon.com.
• Drinking green tea modestly reduces breast cancer risk - J Nutr. 2009 Feb;139(2):310-6 - "Compared with nondrinkers, regular drinking of green tea was associated with a slightly decreased risk for breast cancer (OR, 0.88; 95% CI, 0.79-0.98)" - See green tea extract at Amazon.com.
• Breast cancer cell response to genistein is conditioned by BRCA1 mutations - Biochem Biophys Res Commun. 2009 Jan 3 - "We showed that growth of BRCA1 mutant cells was strongly inhibited by genistein whereas it only had a weak effect in cells expressing wild-type BRCA1 protein. BRCA1 mutant cells hypersensitivity could be linked to higher expression of ERbeta gene, which suggests that genistein may be an efficient inhibitor of cancer development in BRCA1 mutant breast cancer cells"
• Prospective cohort study of lifetime physical activity and breast cancer survival - Int J Cancer. 2008 Nov 17 - "A decreased risk of breast cancer death and all deaths was observed among women in the highest versus the lowest quartiles of recreational activity"
• Urinary melatonin levels and postmenopausal breast cancer risk in the nurses' health study cohort - Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):74-9 - "An increased concentration of urinary aMT6s was statistically significantly associated with a lower risk of breast cancer (odds ratio for the highest versus lowest quartile of morning urinary aMT6s, 0.62 ... Results from this prospective study add substantially to the growing literature that supports an inverse association between melatonin levels and breast cancer risk" - see melatonin at Amazon.com.
• Tea consumption and risk of breast cancer - Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):341-5 - "Tea consumption was not related to breast cancer risk overall (P for trend = 0.18). However, when stratified by age, an inverse association was observed among women less than 50 years: those consuming three or more cups per day had a 37% reduced breast cancer risk when compared with women reporting no tea consumption (age and study site-adjusted odds ratios, 0.63; 95% confidence intervals, 0.44-0.89; P = 0.01) with a significant test for trend (P = 0.01). The inverse association noted among younger women was consistent for in situ and invasive breast cancer, and for ductal and lobular breast cancer ... We observed evidence to support a potential beneficial influence for breast cancer associated with moderate levels of tea consumption (three or more cups per day) among younger women. Further research is needed to confirm this association"
• Conjugated Linoleic Acid (CLA) Inhibits Expression of the Spot 14 (THRSP) and Fatty Acid Synthase Genes and Impairs the Growth of Human Breast Cancer and Liposarcoma Cells - Nutr Cancer. 2009;61(1):114-22 - "We conclude that as in bovine mammary and mouse adipose cells, CLA suppresses S14 and FAS gene expression in human breast cancer and liposarcoma cells. Rescue from the antiproliferative effect of CLA by palmitic acid indicates that reduced tumor lipogenesis is a major mechanism for the anticancer effects of CLA" - See conjugated linoleic acid at Amazon.com.
• Breast Cancer: Diet High In Vegetables, Fruit And Fiber May Cut Risk Of Cancer Recurrence In Women Without Hot Flashes - Science Daily, 12/30/08 - "A secondary analysis of a large, multicenter clinical trial has shown that a diet loaded with fruits, vegetables and fiber and somewhat lower in fat compared to standard federal dietary recommendations cuts the risk of recurrence in a subgroup of early-stage breast cancer survivors – women who didn't have hot flashes – by approximately 31 percent. These patients typically have higher recurrence and lower survival rates than breast cancer patients who have hot flashes"
• How Certain Vegetables Combat Cancer - Science Daily, 12/23/08 - "Breast cancer, the second leading cause of cancer deaths in women, can be protected against by eating cruciferous vegetables such as cabbage and near relatives of cabbage such as broccoli and cauliflower ... Our paper focuses on the anti-cancer activity of one of these compounds, called sulforaphane, or SFN ... SFN inhibits the proliferation of human tumor cells by a mechanism similar to the way that the anticancer drugs taxol and vincristine inhibit cell division during mitosis ... SFN, like the more powerful anticancer agents, interferes with microtubule functioning during mitosis in a similar manner to the more powerful anticancer drugs ... SFN may be an effective cancer preventive agent because it inhibits the proliferation and kills precancerous cells"
• New Anti-cancer Components Of Extra-virgin Olive Oil Revealed - Science Daily, 12/17/08 - "Extra-virgin olive oil is the oil that results from pressing olives without the use of heat or chemical treatments. It contains phytochemicals that are otherwise lost in the refining process. Menendez and colleagues separated the oil into fractions and tested these against breast cancer cells in lab experiments. All the fractions containing the major extra-virgin phytochemical polyphenols (lignans and secoiridoids) were found to effectively inhibit HER2"
• Indole-3-carbinol Inhibits Sp1-Induced Matrix Metalloproteinase-2 Expression To Attenuate Migration and Invasion of Breast Cancer Cells - J Agric Food Chem. 2008 Dec 5 - "Indole-3-carbinol (I3C), a major indole metabolite in cruciferous vegetables, has been shown to inhibit invasion of breast cancer cells ... Migration, invasion, and MMP-2 activity of MCF-7 breast cancer cells were dose-dependently inhibited by I3C. In addition, the MMP-2 mRNA level was also reduced by I3C ... In addition, I3C inhibited the extracellular signal-regulated kinase (ERK) signaling pathway in MCF-7 cells. The results suggest that I3C inhibits MMP-2 expression by blocking the ERK/Sp1-mediated gene transcription to attenuate migration and invasion of breast cancer cells" - See indole-3-carbinol at Amazon.com.
• Dietary intakes of mushrooms and green tea combine to reduce the risk of breast cancer in Chinese women - Int J Cancer. 2008 Oct 1 - "Compared with nonconsumers, the Odds ratios (Ors) were 0.36 (95% CI = 0.25-0.51) and 0.53 (0.38-0.73) for daily intake of >/=10 g fresh mushrooms and >/=4 g dried mushrooms, based on multivariate logistic regression analysis adjusting for established and potential confounders. There were dose-response relationships with significant tests for trend (p < 0.001). The inverse association was found in both pre- and postmenopausal women. Compared with those who consumed neither mushrooms nor green tea, the ORs were 0.11 (0.06-0.20) and 0.18 (0.11-0.29) for daily high intake of fresh and dried mushrooms combined with consuming beverages made from >/=1.05 g dried green tea leaves per day"
• Canola Oil May Affect Breast Cancer Risk - WebMD, 11/18/08 - "Could the type of oil a woman consumes during pregnancy influence her daughter's breast cancer risk years later? ... pregnant women may be better off choosing canola oil over most other vegetable oils ... Corn oil has 50% omega-6 and almost no omega-3, while canola oil has 20% omega-6 and 10% omega-3,""
• Vigorous Exercise Cuts Breast Cancer Risk - WebMD, 10/30/08 - "When we evaluated the relation of vigorous activity to breast cancer among women who were of normal weight ... the risk among women reporting the highest amount of vigorous activity decreased by about 30% compared with women with no vigorous activity"
• Caffeine Consumption Not Associated With Breast Cancer Risk In Most Women, Study Suggests - Science Daily, 10/13/08 - "Consumption of caffeine and caffeinated beverages and foods was not statistically significantly associated with overall risk of breast cancer"
• Vitamin D again linked to breast cancer protection - Nutra USA, 9/26/08 - "Increased intakes of the vitamin were associated with a 24 per cent reduction in the risk of developing ER+ and PR+ tumours" - [Abstract] - See vitamin D at Amazon.com.
• Dietary intakes of omega-6 and omega-3 polyunsaturated fatty acids and the risk of breast cancer - Int J Cancer. 2008 Sep 9 - "Breast cancer risk was not related to any dietary PUFA overall; however, opposite associations were seen according to food sources, suggesting other potential effects than PUFA per se. Breast cancer risk was inversely associated with alpha-linolenic acid (ALA) intake from fruit and vegetables [highest vs. lowest quintile, hazard ratio (HR) 0.74; 95% confidence interval (CI) 0.63, 0.88; p trend < 0.0001], and from vegetable oils (HR 0.83; 95% CI 0.71, 0.97; p trend 0.017). Conversely, breast cancer risk was positively related to ALA intake from nut mixes (p trend 0.004) and processed foods (p trend 0.068), as was total ALA intake among women in the highest quintile of dietary vitamin E (p trend 0.036). A significant interaction was also found between omega-6 and long-chain omega-3 PUFAs, with breast cancer risk inversely related to long-chain omega-3 PUFAs in women belonging to the highest quintile of omega-6 PUFAs (p interaction 0.042). These results emphasize the need to consider food sources, as well as interactions between fatty acids and with antioxidants, when evaluating associations between PUFA intakes and breast cancer risk" - Note:  Alpha-linolenic acid is the vegetable form of omega-3.
• Vitamin D intake and breast cancer risk: a case-control study in Italy - Ann Oncol. 2008 Aug 18 - "The OR for subjects in the three highest deciles of consumption compared with those in the lowest ones combined was 0.79 (95% CI 0.70-0.90). Intake of vitamin D >3.57 mug or 143 IU appeared to have a protective effect against breast cancer. The inverse association was consistent across strata of menopausal status ... This study adds to the existing evidence that vitamin D intake in inversely associated with breast cancer risk" - See vitamin D at Amazon.com.
• Resveratrol May Prevent Breast Cancer - WebMD, 7/7/08 - "when the body's system for processing estrogen gets out of balance, dangerous estrogen metabolites appear. These toxic compounds react with DNA in breast cells and jump-start the growth of tumors ... resveratrol decreases the processing of estrogen into these dangerous compounds. Perhaps more importantly, it also blocks interactions between estrogen metabolites and cellular DNA ... And that's not all. Rogan's team finds that resveratrol increases production of an enzyme that destroys dangerous estrogen metabolites" - [Science Daily] - See resveratrol products at Amazon.com.
• Genistein protects against polycyclic aromatic hydrocarbon-induced oxidative DNA damage in non-cancerous breast cells MCF-10A - Br J Nutr. 2008 Jun 23:1-6 - "These enzymes, in turn, will metabolise the PAH into their ultimate carcinogenic forms. Genistein can significantly suppress the expressions within 5 mum. The comet assay indicated that DMBA introduced DNA damage to these cells, and co-treatment with genistein at 5 or 10 mum could alleviate the damage. In addition to the chelation of DMBA metabolites to DNA, flow cytometry results revealed that oxidation was also a factor of DNA damage. The oxidative DNA damage could be removed by co-treating with 10 mum-genistein. Because no increased oxidative DNA repair was observed, suppression on the cytochrome enzymes appeared to be the underlying mechanism"
• A Mixture of trans, trans Conjugated Linoleic Acid Induces Apoptosis in MCF-7 Human Breast Cancer Cells with Reciprocal Expression of Bax and Bcl-2 - J Agric Food Chem. 2008 Jun 21 - "These findings suggest that incorporation of t, t CLA in the membrane induces a mitochondria-mediated apoptosis that can enhance the antiproliferative effect of t, t CLA in MCF-7 cells" - See conjugated linoleic acid at Amazon.com.
• Genistein reduced the invasive activity of human breast carcinoma cells as a result of decreased tight junction permeability and modulation of tight junction proteins - Cancer Lett. 2008 Jun 14 - "Taken together our results indicate a possible role of genistein as an inhibitor of cancer cell invasion through the tightening of TJs, which may counteract the up-regulation of claudins. In addition, our results indicate that may be beneficial for the inhibition of tumor metastasis"
• Low Melatonin Associated with Increased Risk of Breast Cancer in Postmenopausal Women - Science Daily, 6/15/08 - "women with the lowest levels of melatonin had a statistically significantly higher incidence of breast cancer than those with the highest levels" - See melatonin at Amazon.com.
• Link Between Vitamin D Status And Breast Cancer Illuminated - Science Daily, 5/15/08 - "This is the first study, to our knowledge, to show that higher serum levels of vitamin D are associated with reduced incidence rates of breast cancer worldwide" - See vitamin D at Amazon.com.
• Stay Fit, Avoid Breast Cancer? - WebMD, 5/12/08 - "the women whose activity equaled 13 walking hours a week or 3.25 running hours per week had a 23% lower risk of premenopausal breast cancer compared with the less active women. The strongest association was seen with increased exercise during adolescent and young adult years (ages 12-22)"
• Daily Aspirin May Cut Breast Cancer Risk - WebMD, 4/30/08 - "Overall, NSAID use wasn't associated with breast cancer risk. But women who reported taking daily aspirin were 16% less likely to develop estrogen-receptor positive breast cancer. Those tumors are fueled by estrogen; most breast cancers are estrogen-receptor positive"
• Dietary Lignans Improve Breast Cancer Survival - Medscape, 4/25/08 - "a high intake of lignans was associated with about a 50% reduction in mortality from all causes. This included cardiovascular disease and other cancers" - See flax seed at Amazon.com.
• Coffee May Protect Against Breast Cancer, Study Shows - Science Daily, 4/24/08 - "Depending on which variant of a certain gene a woman has, a coffee consumption rate of at least two-three cups a day can either reduce the total risk of developing breast cancer or delay the onset of cancer"
• High Blood Levels Of Vitamin D Protect Women From Breast Cancer, Study Suggests - Science Daily, 4/22/08 - "Women with a very low blood level of 25(OH)D have a considerably increased breast cancer risk. The effect was found to be strongest in women who were not taking hormones for relief of menopausal symptoms" - See vitamin D at Amazon.com.
• Veggies, Exercise May Cut Cancer Risk - WebMD, 4/15/08 - "Overall, women who engaged in recreational exercise 30 to 150 minutes per week were 50% less likely to have breast cancer than women who exercised less than a half hour per week"
• Green Tea Ingredient, EGCG, Significantly Inhibits Breast Cancer Growth In Female Mice - Science Daily, 4/7/08 - "Green tea is high in the antioxidant EGCG (epigallocatechin-3- gallate) which helps prevent the body’s cells from becoming damaged and prematurely aged ... At the end of the five week period the researchers found that oral consumption of EGCG caused significant decreases in TCSA (66%), tumor weight (68%), IM density 155+/-6 vs.111+/-20 IM#mm^2) and VEGF protein levels (59.0+/-3.7 vs. 45.7+/-1.4 pg/mg) in the breast tumors vs. the control mice, respectively (N=8; P<0.01). Further, VEGF plasma levels were lower in EGCG mice than in control mice (40.8+/-3.5 vs. 26.5+/-3.8 pg/ml P< 0.01)" - [WebMD] - See green tea extract at Amazon.com.
• CXCR4 and CXCL12 down-regulation: A novel mechanism for the chemoprotection of 3,3'-diindolylmethane for breast and ovarian cancers - Cancer Lett. 2008 Mar 28 - "Our data suggest that one mechanism whereby DIM protects against breast, ovarian, and possibly other cancers is through the repression of CXCR4 and/or CXCL12, thereby lowering the invasive and metastatic potential of these cells" - See diindolylmethane at Amazon.com.
• Aspirin Could Reduce Breast Cancer And Help Existing Sufferers, Review of Studies Suggests - Science Daily, 3/6/08 - "Anti-inflammatory drugs like aspirin may reduce breast cancer by up to 20 per cent"
• Plasma Isoflavone Level and Subsequent Risk of Breast Cancer Among Japanese Women: A Nested Case-Control Study From the Japan Public Health Center-Based Prospective Study Group - J Clin Oncol. 2008 Mar 3 - "We found a statistically significant inverse association between plasma genistein and risk of breast cancer, but no association for plasma daidzein. Adjusted odds ratios for the highest versus lowest quartile of plasma level were 0.34 for genistein (95% CI, 0.16 to 0.74; P for trend, .02) and 0.71 for daidzein (95% CI, 0.35 to 1.44; P for trend, .54). Median plasma genistein values in the control group were 31.9 ng/mL for the lowest and 353.9 ng/mL for the highest quartile groups" - See soy isoflavones at Amazon.com.
• Vitamin D Appears to Cut Breast and Colorectal Cancer Risk - Medscape, 2/12/08 - "Compared with a serum 25-hydroxyvitamin D level less than 10 ng/mL, a level of 50 ng/mL reduced the risk for breast cancer by 50%. This level of serum 25-hydroxyvitamin D would require an average intake of 4000 IU of vitamin D per day, although the authors note that intake of 2000 IU per day combined with sun exposure of approximately 12 minutes per day with 50% of the skin exposed could also help patients achieve a serum 25-hydroxyvitamin D level of 50 ng/mL" - See vitamin D at Amazon.com.
• Dietary Fiber Intake Inversely Associated With Breast Cancer Risk - Medscape, 2/8/08 - "Among ever-users of postmenopausal hormones, a significant inverse association was observed between intake of dietary fiber, especially from cereal products, and breast cancer risk for overall, ER+PR+, and ER-PR- tumors. The adjusted relative risk for all invasive tumors was 0.50"
• Coffee, tea, caffeine and risk of breast cancer: A 22-year follow-up - Int J Cancer. 2008 - "our results suggested a weak inverse association between caffeine-containing beverages and risk of postmenopausal breast cancer"
• The combination of epigallocatechin gallate and curcumin suppresses ERalpha-breast cancer cell growth in vitro and in vivo - Int J Cancer. 2007 Dec 20 - "Tumor volume in the EGCG + curcumin treated mice decreased 49% compared to vehicle control mice (p < 0.05), which correlated with a 78 +/- 6% decrease in levels of VEGFR-1 protein expression in the tumors. Curcumin treatment significantly decreased tumor protein levels of EGFR and Akt, however the expression of these proteins was not further decreased following combination treatment. Therefore, these results demonstrate that the combination of EGCG and curcumin is efficacious in both in vitro and in vivo models of ERalpha- breast cancer and that regulation of VEGFR-1 may play a key role in this effect"
• Isoflavones may stop benign breast lumps: study - Nutra USA, 12/18/07 - "the highest plasma levels of genistein (more than 76.95 nanograms per millilitre) were 74 per cent less likely to have breast cancer, and 60 per cent less likely to have benign conditions, relative to women with the lowest average levels (less than 9.42 ng/mL)" - See soy isoflavones at Amazon.com.
• Green Tea Shown To Possess Antitumor Effect In Breast Cancer - Science Daily, 12/8/07 - "green tea has antitumor effect in breast cancer cells ... Dr. Maheshwari’s study observed that green tea can inhibit the invading capacity of these breast cancer cells and have also identified the mechanisms involved in death inducing and invasion inhibiting effects of green tea" - See green tea extract at Amazon.com.
• Intake of fruits, vegetables, and soy foods in relation to breast cancer risk in Korean women: a case-control study - Nutr Cancer. 2007;57(1):20-7 - "Increasing consumption of grapes was linked to a significant protective effect against risk of breast cancer (OR=0.66; 95% CI=0.41-0.86; P<0.01). Among the vegetables, reduced risk was observed with high tomato intake (OR=0.62; 95% CI=0.38-0.81; P<0.01). Among soy foods, high consumption of cooked soybeans, including yellow and black soybeans, had an association with reduced breast cancer (OR=0.67; 95% CI=0.45-0.91; P<0.02)"
• Differential expression of genes induced by resveratrol in human breast cancer cell lines - Nutr Cancer. 2006;56(2):193-203 - "The phytoalexin, trans-resveratrol (RES), is a polyphenolic compound found in plants and fruits that seems to have a wide spectrum of biological activities. It has been found to possess cancer chemopreventive effects by inhibiting diverse cellular events associated with tumor initiation, promotion, and progression. RES is also a phytoestrogen, which binds to and activates estrogen receptors (ERs) that regulate the transcription of estrogen-responsive target genes" - See resveratrol products at Amazon.com.
• Low Calcium May Spur Breast Cancer Spread - oncologystat.com, 10/19/07 - "The study involved implanting breast cancer cells into mice and feeding them a low-calcium diet. The mice experienced a high bone turnover and showed a 43% increase in bone destruction, a 24% increase in tumor area, and a 24% increase in tumor cell proliferation compared to a control group"
• A case-control study on the dietary intake of mushrooms and breast cancer risk among Korean women - Int J Cancer. 2007 Oct 17 - "Both the daily intake (5th vs. 1st quintile, OR = 0.48, 95% CI = 0.30-0.78, p for trend 0.030) and the average consumption frequency of mushrooms (4th vs. 1st quartile, OR = 0.54, 95% CI = 0.35-0.82, p for trend 0.008) were inversely associated with breast cancer risk" - See maitake at Amazon.com and shiitake mushroom supplements at Amazon.com.
• Weight Gain Ups Breast Cancer Risk - WebMD, 10/22/07 - "If you had a weight gain early in life in the absence of weight gain later, it would not be risky in terms of breast cancer ... But weight gain any time after 35 is very predictive of postmenopausal breast cancer"
• Exposure To Sunlight May Decrease Risk Of Advanced Breast Cancer By Half - Science Daily, 10/18/07 - "We believe that sunlight helps to reduce women's risk of breast cancer because the body manufactures the active form of vitamin D from exposure to sunlight ... It is possible that these effects were observed only among light- skinned women because sun exposure produces less vitamin D among women with naturally darker pigmentation" - See vitamin D at Amazon.com.
• Vitamin supplement use and risk for breast cancer: the Shanghai Breast Cancer Study - Breast Cancer Res Treat. 2007 Oct 5 - "a 20% reduction in breast cancer risk was observed with vitamin E supplement use among women with low-dietary vitamin E intake ... A non-significant 20% risk reduction was observed among vitamin B supplement users with low B dietary intake (OR = 0.8; 95% CI, 0.6-1.1). Frequent use of a vitamin B supplement was adversely associated with breast cancer risk among those with high dietary vitamin B intake (OR = 1.4"
• Breast Cancer Risk May Decrease With Increasing Duration of NSAID Use -  Medscape, 10/1/07 - "Use of NSAIDs was associated with a lower risk for breast cancer (odds ratio [OR], 0.76"
• Vitamin D intake and breast cancer risk in postmenopausal women: the Iowa Women's Health Study - Cancer Causes Control. 2007 Sep;18(7):775-82 - "The adjusted RR of breast cancer for women consuming >800 IU/day versus <400 IU/day total vitamin D was 0.89 (95% CI: 0.77-1.03). RRs were stronger among women with negative than positive ER or PR status. The association of high vitamin D intake with breast cancer was strongest in the first 5 years after baseline dietary assessment (RR = 0.66; 95% CI: 0.46-0.94 compared with lowest-intake group), and diminished over time"
• Vitamin D for Cancer Prevention? - WebMD, 9/5/07 - "The 2,000-IU daily dose of vitamin D suggested by the reviewers is currently considered the "tolerable upper limit" for vitamin D ... a projected 50% reduction in colon cancer incidence would require a universal intake of 2,000 IU per day of vitamin D3 ... A similar reduction in breast cancer incidence would require 3,500 IU per day"
• Dietary fiber intake and risk of postmenopausal breast cancer defined by estrogen and progesterone receptor status-A prospective cohort study among Swedish women - Int J Cancer. 2007 Aug 31 - "estrogen receptor (ER)/progesterone receptor (PR)-defined breast cancer risk ... When comparing the highest to the lowest quintile, we observed non-significant inverse associations between total fiber intake and the risk of all tumor subtypes; the multivariate-adjusted RRs were 0.85 (95% CI: 0.69-1.05) for overall, 0.85 (0.64-1.13) for ER+PR+, 0.83 (0.52-1.31) for ER+PR- and 0.94 (0.49-1.80) for ER-PR-. For specific fiber, we observed statistically significant risk reductions for overall (34%) and for ER+PR+ (38%) for the highest versus lowest quintile of fruit fiber, and non-significant inverse associations for other subtypes of cancer and types of fiber. Among ever-users of postmenopausal hormone (PMH), total fiber intake and especially cereal fiber were statistically significantly associated with approximately 50% reduced risk for overall and ER+PR+ tumors when comparing the highest to the lowest quartile, but no association was observed among PMH never users"
• Study Shines More Light On Benefit Of Vitamin D In Fighting Cancer - Science Daily, 8/21/07 - "For the first time, we are saying that 600,000 cases of breast and colorectal cancer could be prevented each year worldwide, including nearly 150,000 in the United States alone ... The serum level recommended by the study would correspond to intake of 2000 International Units per day of vitamin D3 for a meaningful reduction in colorectal cancer" - See vitamin D at Amazon.com.
• Increased folate may slash breast cancer risk - Nutra USA, 8/9/07 - "women in the highest average intake group (456 micrograms of folate per day) had a 44 per cent lower risk of invasive breast cancer than women in the lowest average intake group (160 micrograms of folate per day)" - See folic acid at Amazon.com.
• High folate intake is associated with lower breast cancer incidence in postmenopausal women in the Malmo Diet and Cancer cohort - Am J Clin Nutr. 2007 Aug;86(2):434-43 - "Compared with the lowest quintile, the incidence of invasive breast cancer was reduced in the highest quintile of dietary folate intake (HR: 0.56; 95% CI: 0.35, 0.90; P for trend = 0.02); total folate intake, including supplements (HR: 0.56; 95% CI: 0.34, 0.91; P for trend = 0.006); and dietary folate equivalents (HR: 0.59" - See folic acid at Amazon.com.
• Breast Cancer: More Veggies Not Better - WebMD, 7/17/07 - "eating more than five daily servings of fruits and vegetables doesn't offer extra benefit"
• Diet And Exercise Key To Surviving Breast Cancer, Regardless Of Obesity, Study Suggests - Science Daily, 6/9/07 - "even if a woman is overweight, if she eats at least five servings of vegetables and fruits a day and walks briskly for 30 minutes, six days a week, her risk of death from her disease goes down by 50 percent"
• Vitamin D intake and breast cancer risk in postmenopausal women: the Iowa Women's Health Study - Cancer Causes Control. 2007 Jun 5 - "Vitamin D intake of >800 IU/day appears to be associated with a small decrease in risk of breast cancer among postmenopausal women" - See vitamin D at Amazon.com.
• Preventing Breast Cancer? - Dr. Weil, 5/3/07 - "Take 2 grams of fish oil a day. High omega-3 fatty acid intake significantly reduces your risk of breast cancer" - See Mega Twin EPA at Amazon.com or Jarrow Max DHA at Amazon.com.
• Erythrocyte fatty acids and breast cancer risk: a case-control study in Shanghai, China - Am J Clin Nutr. 2007 Apr;85(4):1090-7 - "Our results support a protective effect of n-3 fatty acids on breast cancer risk" - See Mega Twin EPA at Amazon.com.
• Vitamin d and reduced risk of breast cancer: a population-based case-control study - Cancer Epidemiol Biomarkers Prev. 2007 Mar;16(3):422-9 - "We found strong evidence to support the hypothesis that vitamin D could help prevent breast cancer. However, our results suggest that exposure earlier in life, particularly during breast development, maybe most relevant"
• Dietary carotenoids and risk of breast cancer in Chinese women - Asia Pac J Clin Nutr. 2007;16 Suppl:437-42 - "higher intake of lycopene, beta-carotene and beta-cryptoxanthin is associated to a lower risk of breast cancer among Chinese women"
• Plant Estrogen May Cut Breast Cancer - WebMD, 3/20/07 - "A diet rich in estrogen-like compounds found in flaxseed, tea, and many plants may help curb breast cancer after menopause ... Women with the highest lignan intake were 17% less likely to be diagnosed with breast cancer during the study than those with the lowest intake"
• Exercise Helps Prevent Breast Cancer - WebMD, 2/16/07 - "women who get more than six hours of strenuous exercise a week, and have no family history of breast cancer, may be 23% less likely to develop the disease than women who don't exercise at all"
• Vitamin D Appears to Cut Breast and Colorectal Cancer Risk - Medscape, 2/12/07 - "Compared with a serum 25-hydroxyvitamin D level less than 10 ng/mL, a level of 50 ng/mL reduced the risk for breast cancer by 50%. This level of serum 25-hydroxyvitamin D would require an average intake of 4000 IU of vitamin D per day, although the authors note that intake of 2000 IU per day combined with sun exposure of approximately 12 minutes per day with 50% of the skin exposed could also help patients achieve a serum 25-hydroxyvitamin D level of 50 ng/mL" - See vitamin D at Amazon.com.
• Vitamin D Backed For Cancer Prevention In Two New Studies - Science Daily, 2/8/07 - "Two new vitamin D studies using a sophisticated form of analysis called meta-analysis, in which data from multiple reports is combined, have revealed new prescriptions for possibly preventing up to half of the cases of breast cancer and two-thirds of the cases of colorectal cancer in the United States ... The serum level associated with a 50 percent reduction in risk could be maintained by taking 2,000 international units of vitamin D3 daily plus, when the weather permits, spending 10 to 15 minutes a day in the sun" - See vitamin D at Amazon.com.
• Phytoestrogens and indicators of breast cancer prognosis - Nutr Cancer. 2006;56(1):3-10 - "In women with higher intakes of phytoestrogens, there was a 32% reduction in the odds of being diagnosed with any stage of cancer other than stage 1 (95% confidence interval, CI = 0.49-0.93; P = 0.02), a 38% reduction in odds of being diagnosed with positive lymphovascular invasion (95% CI = 0.40-0.95; P = 0.03), and a 66% increase in the odds of being diagnosed with a positive progesterone receptor"
• Low-Fat Diet May Help Breast Cancer - WebMD, 12/16/06
• Pro-vitamin E Shown To Be Active Against Breast Cancer Cells - Science Daily, 12/9/06 - "pro-vitamin E or alpha-tocopheryl succinate can reduce tumour volume in experimental animals with high levels of HER2"
• Soy, Fish May Cut Cancer Risk - WebMD, 11/14/06 - "Women who ate the most soy as teens or adults were about 25% less likely to have breast cancer than those who skimped on it"
• Control hormones to stop breast cancer - MSNBC, 10/27/06
• Vitamin D May Slow Breast Cancer - WebMD, 10/17/06 - "women with early-stage breast cancer had much higher levels of vitamin D in their blood than women with more advanced disease"
• Regular Exercise, Keeping Weight In Check Reduces Breast-cancer Risk In Postmenopausal Women - Science Daily, 10/12/06 - "women with high BMI and low physical-activity had mean estrogen concentrations that were 50 percent to 100 percent higher than that of women with low BMI and high activity levels"
• Idleness, Weight Up Breast Cancer Risk - WebMD, 10/10/06 - "postmenopausal women who exercise and keep their weight down substantially reduce their risk of breast cancer"
• Indole-3: A Broccoli Cure? - Dr. Weil, 9/15/07 - see my I3C page.
• Exercise May Up Breast Cancer Survival - WebMD, 9/11/06
• Ginseng linked to improved breast cancer outcomes - Nutra USA, 8/17/06
• Weight Gain May Increase Risk of Breast Cancer in Postmenopausal Women - Doctor's Guide, 7/12/06 - "Women who gained about 55 pounds or more since age 18 were at a 45% increased risk of breast cancer, compared with those who maintained their weight ... Women who gained about 22 pounds or more since menopause were at an 18% increased risk of breast cancer ... Those who lost about 22 pounds or more since menopause (and kept the weight off) and had never used postmenopausal hormones were at a 57% lower risk of breast cancer than those who simply maintained their weight"
• Veggies may keep breast cancer from returning - MSNBC, 4/14/06 - "After about seven years, women who began with the highest levels of carotenoids in their blood showed 43 percent less risk of developing breast cancer again when compared to women with the lowest carotenoid levels"
• Food Antioxidants, Vitamin D Fight Breast Cancer - HealthDay, 4/7/06 - "postmenopausal women who consumed high levels of flavonoids, a class of antioxidants found in plants, had a 45 percent lower risk of breast cancer ... Those who had the highest levels of intake of kaempferol had a 38 percent decrease in the incidence of ovarian cancer compared to women with the lowest levels of this flavonoid ... those with the highest blood levels of a vitamin D metabolite known as 25-hydroxyvitamin D had a 50 percent reduced risk of breast cancer" - [Science Daily]
• Tea May Fight Ovarian, Breast Cancers - WebMD, 4/5/06 - "women who increase their consumption of kaempferol, a type of flavonoid, can lower their risk of ovarian cancer by nearly 40% ... women who consume a diet rich in other types of flavonoids - specifically, flavones, flavan-3-ols, and lignans -- can reduce their chance of developing breast cancer by 26% to 39%" - See iHerb or Vitacost green tea products.
• Vitamin D linked to lower breast cancer risk - Nutra USA, 4/4/06 - "a serum vitamin D level of 52 nanograms per milliliter was associated with a 50 percent reduction in breast cancer risk. To have such a serum vitamin level would require a daily intake of about 1,000 International Units (IU)" - See iHerb or Vitacost vitamin D products.
• Researchers Find Ginseng May Improve Breast Cancer Outcomes - Science Daily, 3/16/06 - "They also found significant improvements in both survival and quality of life measures in patients who used ginseng" - See ginseng at Amazon.com.
• Soy Phytoestrogens May Block Estrogen Effects - Science Daily, 1/16/06 - "the addition of high levels of dietary soy isoflavones tended to block estrogen effects in breast tissue. This finding suggests that postmenopausal women with higher levels of estrogen may derive the greatest benefit from soy"
• Consumption of coffee, but not black tea, is associated with decreased risk of premenopausal breast cancer - J Nutr. 2006 Jan;136(1):166-71 - "Among premenopausal women, consumption of regular coffee was associated with linear declines in breast cancer risk (P for trend = 0.03); consumers of >/=4 cups/d experienced a 40% risk reduction"
• Eat Dairy Foods, Avoid Breast Cancer? - WebMD, 12/14/05 - "Women who had the highest dietary calcium intake were 20% less likely to have been diagnosed with breast cancer than those whose diets were lowest in dietary calcium"
• Turmeric for Breast Cancer Prevention? - Dr. Weil, 12/2/05
• Breast cancer and dietary factors in Taiwanese women - Cancer Causes Control. 2005 Oct;16(8):929-37 - "Cases also consumed statistically significant less supplements such as vitamins and mineral than controls ... Our results indicate a strong protective effect of dietary supplements and a harmful effect of dietary fats on the risk of breast cancer among women in Taiwan"
• Primrose Oil Component Cuts Levels Of Cancer-causing Gene Her-2/neu - Science Daily, 11/4/05 - "Gamma-linolenic acid (GLA), a substance in evening primrose oil and several other plant oils used in herbal medicine, inhibits action of Her-2/neu, a cancer gene that is responsible for almost 30 percent of all breast cancers" - See borage oil at Amazon.com.
• Plant oil 'acts like cancer drug' - BBC News, 11/2/05 - "It is down to a substance in the oil called gamma-linolenic acid that acts on the same receptor in tumours as the powerful breast cancer drug Herceptin" - See borage oil at Amazon.com.
• Spice Ingredient May Cut Breast Cancer Spread - WebMD, 10/17/05
• Eat wisely to reduce breast cancer risk - MSNBC, 7/22/05 - "The women who followed a low-fat diet in this study reduced their risk of a recurrence during the next five years by 24 percent ... Keep in mind that omega-3 fats may be protective"
• Curry Spice May Curb Breast Cancer's Spread - WebMD, 6/9/05 - "Less than a quarter of the mice in the curcumin-plus-Taxol group had cancer that spread to the lungs. So did half of the curcumin group. In comparison, cancer spread to the lungs in three-fourths of the Taxol group and almost all (95%) mice that got no treatment" - See iHerb or Vitacost curcumin products.
• Omega-3 Offers Hope For New Anti-breast Cancer Drugs - Science Daily, 6/8/05 - "Compounds of Omega-3 fatty acids and propofol reduce the ability of breast cancer cells to develop into malignant tumours, inhibiting cancer cell migration by 50% and significantly reducing their metastatic activity ... Propofol is a potent anti-oxidant known to inhibit cancer cell migration by only 5-10%"
• Weight Gain Affects Breast Cancer Survival - Physician's Weekly, 5/16/05
• Statin Drugs Linked to Reduced Cancer Risk - WebMD, 5/16/05 - "During a six-year period, women who used statins reduced their risk of breast cancer by more than half (51%) compared with nonusers" - See Zocor at International Anti-aging Systems or SuperSaverMeds.com.
• Breast Cancer Protection Starts in the Womb - WebMD, 4/20/05 - "Mothers who choose foods packed with omega-3 fatty acids during pregnancy and while nursing and then feed their kids such a diet after weaning may reduce the risk of breast cancer in their daughters by nearly 90%, early research in mice indicates"
• Soy protein could protect against breast cancer, say researchers - Nutra USA, 4/13/05 - "Eating soy protein on a regular basis may reduce a woman’s chance of developing breast cancer by up to 22 percent"
• Disease-fighting Chemicals In Apples Could Reduce The Risk Of Breast Cancer, Cornell Study In Rats Suggests - Science Daily, 3/12/05 - "tumor incidence was reduced by 17, 39 and 44 percent in rats fed the human equivalent of one, three or six apples a day, respectively, over 24 weeks ... Studies increasingly provide evidence that it is the additive and synergistic effects of the phytochemicals present in fruits and vegetables that are responsible for their potent antioxidant and anticancer activities"
• An Apple a Day May Cut Breast Cancer Risk - WebMD, 3/2/05 - "For humans, the doses equaled eating one, three, or six apples per day ... After 24 weeks, breast tumor rates were 17% lower in the rats receiving the low dose of the apple extract, 39% lower with the medium dose, and 44% lower with the high dose"
• Seaweed May Lower Breast Cancer Risk - WebMD, 2/2/05
• Calcium, Vitamin D Intake Low among Breast Cancer Patients - Doctor's Guide, 12/14/04
• Anticancer Diet - Time, 11/15/04 - "eating at least 35 servings of fruits and vegetables a week can cut the risk of developing hormone-stimulated breast-cancer tumors by 35% in postmenopausal women ... leafy greens and colorful vegetables like carrots, squash, tomatoes and peppers, which are rich in lycopene and beta carotene, are especially potent cancer fighters"
• Exercise Boosts Recovery From Breast Cancer - Science Daily, 10/18/04
• Eating More Soy-rich Foods Could Reduce Spread Of Breast Cancer - Science Daily, 9/29/04 - "eating a soy rich products such as soy milk, soy drinks and desserts, could have an important role in preventing the spread of cancer cells in the body"
• Fish Oil's Breast Cancer Benefits May Vary - WebMD, 9/23/04
• How To Prevent Breast Cancer Anti-Cancer Power of Coenzyme Q10 - Life Extension Magazine, 1/96
• Anti-cancer Compound In Vegetables Found To Block Late-stage Breast-cancer Cell Growth - Science Daily, 9/1/04 - "The compound, in broccoli and other cruciferous vegetables ... sulforaphane (SUL) ... We were surprised and pleased to find that SUL could block the growth of breast cells that were already cancerous ... SUL's actions appear similar to a group of anticancer drugs currently in use, such as Taxol"
• Overweight? Good Cholesterol May Fight Cancer - WebMD, 8/3/04 - "overweight, postmenopausal women with high levels of good HDL cholesterol have 67% less breast cancer than similar women with low HDL levels"
• Aspirin May Protect Against Breast Cancer - WebMD, 5/25/04 - "taking aspirin at least once a week for six months or longer reduced the risk of breast cancer by 20%, compared with women who never took aspirin. Taking a daily aspirin reduced risk by more than 25%"
• Role of vitamins in the risk, prevention, and treatment of breast cancer - Curr Opin Obstet Gynecol. 2004 Feb;16(1):19-25 - "High intake of folate or adequate circulating levels of folate may reduce the risk of breast cancer. Adequate folate levels may be particularly important for women who are at higher risk of breast cancer because of high alcohol consumption. The inverse association between vitamin D and risk of breast cancer needs to be evaluated in more studies" - See iHerb or Vitacost folic acid products.
• Exercise Helps Breast Cancer Fight - Intelihealth, 3/29/04
• Diet has impact on breast cancer, say scientists - Nutra USA, 3/25/04
• Vitamin D to protect women - Nutra USA, 3/23/04 - "Now the researchers believe that a contributing factor to high rates of the cancer may be low levels of vitamin D" - See iHerb or Vitacost vitamin D products.
• Does tea really fight cancer? - MSNBC, 11/21/03 - "A new study of the potential link of green tea consumption with lower risk of breast cancer does suggest a protective benefit. Asian-American women who averaged at least three six-ounce cups of green tea per week were about half as likely to develop breast cancer as those who drank none ... One of the strengths of this study is that researchers statistically adjusted for the effects of many other influences on breast cancer risk"  - See iHerb or Vitacost green tea products. - Ben
• Cutting Genetic Breast Cancer Risk - WebMD, 10/23/03
• Walking Away from Breast Cancer? - Dr. Weil, 10/20/03
• Is Breast Cancer Treatment Shorter Today? - Dr. Weil, 10/6/03
• Modest Exercise Lowers Breast Cancer Risk - WebMD, 9/9/03 - "exercising a mere 1 1/4 to 2 1/2 hours each week -- walking briskly or similar exercise -- reduced the risk of breast cancer by 18% compared with inactive women. That protective effect is only slightly less than the 22% reduced risk observed in women who exercise at least 10 hours a week"
• Burger Diet Raises Breast Cancer Risk - WebMD, 7/15/03 - "The increase was most closely linked with animal fat -- specifically from animal fat -- and, more specifically, red meat and high-fat dairy foods"
• High Cysteine Levels Linked to Lower Rates of Breast Cancer - Doctor's Guide, 7/15/03 - "Women in the highest quintile for measured cysteine levels in this study had a 56% lower risk of invasive or in situ breast cancer than women in the lowest quintile ... The findings were more pronounced when only invasive cancer was considered ... Cysteine or its precursors might have the potential to be chemoprotective against breast cancer" - See iHerb or Vitacost cysteine products.
• NSAID Use Linked to Lower Rates of Breast Cancer - Doctor's Guide, 7/15/03 - "Ten years or more of ibuprofen use reduced a patient's risk nearly in half (RR=0.51, P<0.04), and just 1 to 4 years of regular use was associated with a 29% reduction in risk. The effect of acetylsalicylic acid (Aspirin) was weaker, with 10 years of use of full-strength Aspirin associated with a 21% risk reduction that did not achieve significance ... Neither acetaminophen nor low-dose Aspirin was associated with a reduction in breast-cancer risk ... he found the evidence of a chemoprotective effect compelling enough to treat himself with 200 mg of ibuprofen per day" - See ibuprofen at Amazon.com.
• Best Bet for Breast Cancer Survivors? - Dr. Weil, 7/15/03
• Hormone Melatonin Slows Breast Cancer - WebMD, 7/14/03 - "The nighttime hormone melatonin puts breast cancer cells to sleep. It also slows breast cancer growth by 70%" - See iHerb or Vitacost melatonin products.
• Chemical in Miso and Other Soy Foods Believed to Block Certain Tumors - WebMD, 6/17/03 - "identified 21,852 women between the ages of 40 and 59 and surveyed them about various lifestyle issues ... They traced the women 10 years later ... Women with the most isoflavones in their diet had the lowest risk of breast cancer. This was especially true of postmenopausal women"
• Selenium Supplements May Reduce Breast Cancer Risk in Some - WebMD, 6/16/03 - "a certain version of the gene was associated with a higher breast cancer risk. That same gene was also less responsive to selenium stimulation ... that means people with this genetic variation may benefit from selenium supplements but they require a higher dose to achieve selenium's protective effect against cancer"
• Night Shifts May Raise Cancer Risk - WebMD, 6/3/03 - "Data from an ongoing study of almost 80,000 nurses already suggest that working nights increases a woman's risk of breast cancer ... a new analysis points to a similar association for colorectal cancer ... "The peak production of melatonin occurs at about 1 or 2 a.m." Exposure to light at night stops the production of melatonin" - See iHerb or Vitacost melatonin products.
• Yoga Helps Breast Cancer Patients - WebMD, 6/3/03
• Breast Cancer: Beating the Odds? - Dr. Weil, 5/8/03
• Breast Cancer Survivors: Get Moving - WebMD, 5/7/03
• Dietary intake and risk of postmenopausal breast cancer - Cancer Causes Control 2003 Feb;14(1):19-27 - "Red meat intake was significantly associated with an increased breast cancer risk (p for trend = 0.002) and fish (including fried fish) and dairy product intake was inversely associated with breast cancer risk (p for trend = 0.04 and 0.05, respectively). No significant associations were noted betwen fruit or vegetable intake and breast cancer risk"
• Cholesterol Drugs: Breast Cancer Treatment? - WebMD, 4/10/03 - "One reason cancer cells grow so fast is that they lack biochemical brakes that slow cell growth ... Mevacor -- and, likely, other statins -- lets these growth-brakes build up inside cancer cells -- making them a potentially useful breast cancer treatment down the road" - Note: Red yeast rice is a non-prescription statin but you should still check with your physician.
• Painkillers Help Prevent Breast Cancer - WebMD, 4/9/03
• Use of Non-steroidal Anti-inflammatory Drugs Dramatically Reduces Risk of Breast Cancer - Doctor's Guide, 4/8/03
• Folate, Vitamin B6 Reduce Breast Cancer Risk Among Moderate Drinkers - WebMD, 3/4/04 - "They found women with the highest folate levels were 27% less likely to have breast cancer than those with the lowest folate levels. And the reduction in breast cancer risk was much greater among women who drank about one glass of wine or a cocktail per day. These moderate drinkers with high folate levels were 89% less likely to develop breast cancer than those who drank less than one drink per day ... Women with high levels of vitamin B6 also had about a 30% lower risk of breast cancer than those with low levels of this nutrient. Although high levels of vitamin B12 seemed to protect premenopausal women against breast cancer, the effect was not found among postmenopausal women" - See iHerb or Vitacost folic acid products.
• Eggs May Lower Breast Cancer Risk - WebMD, 2/20/03 - "eating about three eggs a week during adolescence decreased the risk of breast cancer by 18%. Diets rich in vegetable oils and dietary fiber had similar effects. But eating roughly one pat of butter a day increased risk by 6% ... eggs may be protective because they are high in essential amino acids, vitamins, and minerals. And studies suggest that fiber-rich foods reduce estrogen levels"
• Exercise Cuts Breast Cancer Risk - WebMD, 2/10/03 - "women who reported high levels of physical activity from as young as age 16 in some cases cut their risk of developing breast cancer after menopause in half, compared to women who reported no strenuous activity ... The study has a drawback, though, that all such studies face, which is what's called a "healthy patient bias." In this case, women who exercise often might be more apt to take care of themselves in other ways, so that a decrease in breast cancer later in life may not be due to the exercise itself, but rather some other associated factor. The researchers accounted for this by factoring in subjects such as smoking history and weight. "After adjusting for all these factors we're pretty confident that what we see is the effect of exercise,""
• Breast Cancer Answers: Strategies Show Promise In Mice - Intelihealth, 10/23/02 - "Another study found that young female mice who ate lots of fish oil had lower breast cancer rates"
• Eating Lots of Tofu May Prevent Breast Cancer - WebMD, 10/2/02
• Got Milk - WebMD, 9/27/02 - "A combination of soy and cow's milk could have some beneficial, anti-cancer nutrients ... She explains that conjugated linoleic acid, or CLA, is the key to the cow's role in cancer prevention. CLA is a minor fatty acid found in milk and milk products and beef ... He says he thinks the most potent cancer-fighting component of soy is a compound called genistein ... He demonstrated that by feeding rats a diet containing genistein before exposing them to a cancer-causing drug. The number of breast tumors was reduced by 50%" - See iHerb and Vitacost CLA products.
• Diet Rich In Soy Protein Lowers Estrogens Associated With Breast Cancer - Intelihealth, 9/24/02 - "Consuming tofu and other soy-based foods significantly lowers levels of a class of estrogens normally associated with breast cancer risk in postmenopausal women ... The study found a link between soy-rich diets consumed by Asian women in Singapore and reduced levels of an estrogen called estrone, the predominant form of estrogen in women following menopause ... estrone levels did not decline in a linear manner with increasing soy intake; an apparent reduction was only seen among those in the top 25 percent of soy protein consumers ... The study also showed that hormone levels remained unaffected by other dietary and lifestyle choices. These included consumption of alcohol, coffee, tea, fat, fiber and various micronutrients, including vitamins A, C and E, along with calcium and carotenoids ... There is a suggestion that weight change (particularly weight increase) has a profound influence on breast cancer rates in Asian-American women"
• New Broccoli Compound Appears Promising Against Breast Cancer - Intelihealth, 8/19/02 - "Called oxomate, the synthetic compound works like its natural counterpart, sulforaphane, which was recently identified as a cancer-preventive agent in broccoli and other cruciferous vegetables (such as cabbage and Brussels sprouts). Both compounds boost the body's production of phase II enzymes, which can detoxify cancer-causing chemicals and reduce cancer risk ... But the natural broccoli compound, sulforaphane, can be toxic in high doses ... It is also difficult and expensive to synthesize ... oxomate was seven times less toxic than sulforaphane ... In tests on female rats, those that were fed oxomate after exposure to cancer-inducing chemicals had up to a 50 percent reduction in the number of breast tumors"
• Breast Cancer May Be Thwarted By Carotenoids - Doctor's Guide, 5/23/02 - "These results suggest carotenoids may protect against development of breast cancer" - See Jarrow Formulas, CarotenALL, Mixed Carotenoid Complex at Amazon.com.
• Does Vitamin E Prevent Breast Cancer? - Life Extension Magazine, 5/02 - "premenopausal women with a family history who consumed the highest quantity of vitamin E enjoyed a 43% reduction in breast cancer incidence compared to only a 16% risk reduction for women without a family history of breast cancer.[11] Based on this study, vitamin E appears to protect against genetic- predisposed breast cancer better than environmental-induced breast cancer. (Note that nutrients like indole-3-carbinol may specifically protect against environmental breast carcinogens.)"
• What's Wrong With Vitamin E? - Life Extension Magazine, 5/02 - "Tocotrienols and breast cancer ..." - See Jarrow FamilE (contains all eight members of the vitamin E family, includes Tocomin) at Amazon.com.
• Exposure To Sunlight Lowers Risks Of Four Cancers - Doctor's Guide, 4/4/02 - "exposure to sunlight contributes to non-melanoma skin cancer. "By contrast, several ecological studies suggest that sunlight may protect against female breast, ovarian, prostate, and colon cancer, all diseases that contribute to a substantially higher proportion of cancer mortality in the western industrialized world." ... Some studies have suggested an association between circulating vitamin D in blood, which is largely derived from sunlight, or dietary vitamin D and colorectal, prostate and female breast cancers"
• Some Herbs Boost Breast Cancer Risk - WebMD, 3/26/02 - "Our studies show that dong quai and ginseng stimulate the growth of [breast cancer] cells"
• Serum Levels of Micronutrients, Antioxidants and Total Antioxidant Status Predict Risk of Breast Cancer in a Case Control Study - The American Society for Nutritional Sciences J. Nutr. 132:303-306, 2002 - "Blood samples were collected from 153 breast cancer cases and 151 controls. Serum samples were analyzed for retinol, -tocopherol, lycopene, - and ß-carotene by HPLC, and total antioxidant status by the Trolox-equivalent antioxidant assay ... After adjustment for age at menarche, parity, dietary fat and alcohol intake, we observed the following reductions in odds ratios for breast cancer risk comparing the highest with the lowest quartiles: 0.47 [95% confidence interval (CI) 0.24, 0.91] for ß-carotene; 0.53 (CI 0.28, 1.01) for retinol; 0.50 (CI 0.26, 0.97) for bilirubin and 0.47 (CI 0.24, 0.94) for total antioxidant status. We conclude that increased serum levels of ß-carotene, retinol, bilirubin and total antioxidant status are associated with reductions in breast cancer risk"
• Estrogen's Two-Way Street - Nutrition Science News, 11/01 - "Studies show that when 2-hydroxylation increases, the body resists cancer, and that when 2-hydroxylation decreases, cancer risk increases ... Cell-culture studies and human clinical trials have shown that I3C at doses of 200­400 mg/day can influence estrogen metabolism and promote formation of 2-OH-estrone, and therefore may be useful in breast cancer prevention"
• Green Tea, Glycine May Slow Tumor Growth - WebMD, 11/2/01 - "high levels of glycine reduced breast tumor growth rates by 15% in rats by blocking the growth of new tumor-feeding blood vessels. The special diet also reduced wound-healing by 30% ... Tumors and wounds have one very important thing in common -- they both produce new blood vessels through the same mechanism, known as angiogenesis ... If you can block one response, you can block the other"
• Acupuncture Relieves Nausea And Pain Following Major Breast Surgery - Intelihealth, 10/18/01
• Breast Cancer and the Night Shift: Is There A Link? - WebMD, 10/17/01
• Drink To Breast Health - Intelihealth, 10/9/01 - "Possible anti-cancer factors found in milk include calcium, vitamin D and CLA (conjugated linoleic acid). A recent Finnish study found that women with breast cancer had significantly lower levels of CLA in their diets and blood, compared with women without breast cancer. CLA has been shown to block the local growth and spread of breast cancer in animal studies"
• Activity Could Lower Cancer Risk - Intelihealth, 10/1/01
• Physical activity Over Lifetime Could Reduce Breast Cancer Risk - Doctor's Guide, 9/27/01
• Flaxseed May Fight Breast Cancer In Postmenopausal Women - Intelihealth, 8/30/01
• Can Flax Beat Soy as Breast Cancer Buster? - WebMD, 8/30/01
• Keeping Weight Down Can Save You From Breast Cancer - WebMD, 8/20/01
• Curcumin protects against mammary tumors in rats - Life Extension Magazine, 8/01
• Dr. Weil: Chemo OK, but other treatments needed - CNN, 4/13/01
• I3C and DIM: Keys to Cancer Prevention? - Nutrition Science News, 4/01 - "Increased 16-alpha-hydroxyestrone production has been linked to an increase in breast cancer. Based on estrogen metabolism's influence on breast-cancer risk, researchers speculate that reducing hydroxylation of estrone's 16th carbon and increasing hydroxylation of the second carbon would be a wise, protective measure ... The minimum effective dose to increase the ratio of 2-hydroxyestrone to 16-alpha-hydroxyestrone was 300 mg/day ... Most of the research thus far has focused on I3C, a phytonutrient converted by stomach acid to DIM, indolylcarbazole, and other metabolites ... A 350­500 mg dose of I3C is roughly equal to 300­500 mg of raw cabbage or brussels sprouts or about 3 cups of broccoli"
• Newer Agents Offer Better Hot Flash Control In Breast Cancer Patients - Doctor's Guide, 4/4/01 - "If hot flashes are mild and/or the patient is risk averse, vitamin E (800 IU/day) is reasonable to try, because it is safe, inexpensive, and has some demonstrated efficacy. A reasonable next step is to use other non-hormonal agents that may have more efficacy than vitamin E, but also have the associated drawbacks of higher cost and worse side effects"
• Somers' cancer treatment worries some experts - CNN, 3/30/01 - see my Iscador page.
• Exercise Benefits Patients Being Treated For Early Stage Breast Cancer - Doctor's Guide, 1/31/01
• Women Battling Breast Cancer Should Stay in Fighting Shape, Exercise Important During Breast Cancer Treatment - WebMD, 1/30/01
• Soy and Health: What's the Scoop? Most Recent Addition to Soy Research Shows Lower Breast Cancer Risk - WebMD, 12/21/00
• A Muffin a Day for Breast Cancer? If It Contains Flaxseed Oil, May Have Benefits Similar to Potent Drug - WebMD, 12/8/00 - "the investigators found that flaxseed oil's ability to reduce tumor growth is comparable to tamoxifen." - See flaxseed
• Researchers Find Phytochemicals In Apples May Fight Off Cancer - Intelihealth, 8/22/00
• Know Your Breast Cancer Prevention Options - WebMD, 7/20/00
• I3C Indole 3 carbinol The Tamoxifen Substitute - Life Extension Foundation, 10/99
• Exercise May Reduce Breast Cancer - Intelihealth, 10/26/99
• Elevated Prolactin Linked To Breast Cancer - Life Extension Magazine, 6/99
• Using natural therapies for the prevention of breast and other forms of cancer - Life Extension Magazine, 6/99
• Co-Q10 and Cancer - Nutrition Science News, 4/99
• Natural Sugar-Phosphate Compound Shows Promise In Cancer - Doctor's Guide, 3/30/98 (see my IP-6 page)
• Chalk Up Another One For Broccoli! Chemical In Vegetable Shown To Halt Growth Of Breast Cancer Cells - Science Daily, 2/16/98
• Morphological and biochemical status of the mammary gland as influenced by conjugated linoleic acid: implication for a reduction in mammary cancer risk - Cancer Res. 1997 Nov 15;57(22):5067-72 (See my CLA page)
• Study: Grapes inhibit cancer growth - CNN, 1/10/97 (see my grape seed extract page)
• Partial and complete regression of breast cancer in patients in relation to dosage of coenzyme Q10 -  Biochem Biophys Res Commun 1994 Mar 30;199(3):1504-8 - see my coenzyme Q10 page.

Other News:

• Long-term metformin use is associated with decreased risk of breast cancer - Diabetes Care. 2010 Mar 18 - "The mean age was 67.5 (+/-std 10.5) years at the time of the cancer diagnosis. Long-term use of 40+ prescriptions (>5 years) of metformin, based on 17 exposed cases and 120 exposed controls, was associated with an adjusted OR of 0.44 (95% CI 0.24-0.82) for developing breast cancer, as compared to no use of metformin" - See metformin at OffshoreRx1.com.
• MRI finds tumors in second breast of women diagnosed with cancer in one breast, study suggests - Science Daily, 3/8/10
• Most early-stage breast cancer patients may not need radiation after mastectomy - Science Daily, 3/6/10
• Long waits for radiotherapy linked to increased recurrence of breast cancer - Science Daily, 3/2/10
• How estrogen can interfere with chemotherapy's fight against breast cancer - Science Daily, 2/23/10
• Statins and Breast Cancer in Postmenopausal Women without Hormone Therapy - Anticancer Res. 2009 Dec;29(12):5143-5148 - "Overall, there was no association between the use of statins and breast cancer risk odds ratio (OR)=1.3 (95% confidence interval (CI) 0.7-2.5). However, risk varied by hormone receptor status. Compared to non-users, obese women who used hydrophobic statins had an elevated risk of progesterone receptor-negative (PR(-)) breast cancer OR=4.0 (95% CI 1.2-13.8), but not of tumors with other hormone receptor profiles. The risk for breast cancer was also significantly increased among overweight women who used hydrophobic statins for less than or equal to 4 years OR=4.1 (95% CI 1.2-14.4). CONCLUSION: This observational study found an increased risk of breast cancer related to duration of statins use and PR(-) among postmenopausal women"
• Sexual Dysfunction Common Among Breast Cancer Patients - Medscape, 12/15/09
• Alcohol consumption increases risk of breast cancer recurrence, study finds - Science Daily, 12/10/09
• Decline in breast cancer: Not just because of hormone therapy - Science Daily, 12/7/09 - "the change in hormone therapy use only accounted for a decline of about 3 percent, so there's another 4 percent that is being caused by something we do not yet know"
• Pregnancy Protein May Slow Breast Cancer - WebMD, 11/24/09
• Persistent Pain Common For Many Women 2 To 3 Years After Breast Cancer Treatment - Science Daily, 11/10/09
• Plastic Surgeons Offer Microsurgery Technique For Breast Reconstruction, Tummy Tuck After Mastectomy - Science Daily, 11/5/09
• Radiation Therapy After Lumpectomy For Breast Cancer Can Be Safely Reduced To 4 Weeks - Science Daily, 11/4/09
• Three-week Course Of Breast Radiation May Be As Effective As Conventional 5- To 7-week Course For Early Breast Cancers - Science Daily, 11/4/09
• Quick Radiation Works for Breast Cancer - WebMD, 11/4/09
• Surgeons' Unanimous Consensus: Needle Biopsy Is Gold Standard For Breast Cancer Diagnosis - Science Daily, 10/7/09
• Nexavar May Treat Advanced Breast Cancer - WebMD, 9/24/09
• Switching Early Breast Cancer Patients To Exemestane Improves Long-term Survival, Study Finds - Science Daily, 9/21/09
• Treating Bone Loss In Breast Cancer Survivors: Cancer Drugs Aren't The Only Culprits - Science Daily, 9/21/09
• Medications Effective In Reducing Risks For Breast Cancer Can Also Cause Serious Side Effects - Science Daily, 9/18/09 - "The most common side effects for tamoxifen are flushing and other vasomotor symptoms (e.g., night sweats, hot flashes), vaginal discharge and other vaginal symptoms such as itching or dryness; for raloxifene, side effects include vasomotor symptoms and leg cramps; and for tibolone, side effects include vaginal bleeding ... Tamoxifen increases risks of endometrial cancer, hysterectomies and cataracts compared with the other drugs. Tamoxifen and raloxifene increase risk of blood clots, although tamoxifen's risk is greater. Tibolone carries an increased risk of stroke"
• Breast Cancer: Risk Increases For Smokers And Overweight Women - Science Daily, 9/1/09
• Low-dose Estrogen Shown Safe And Effective For Metastatic Breast Cancer - Science Daily, 8/19/09
• MRI May Cause More Harm Than Good In Newly Diagnosed Early Breast Cancer - Science Daily, 8/15/09
• Metabolic Factors May Play A Role In Risk For Breast Cancer - Science Daily, 6/30/09 - "The metabolic syndrome is characterized by elevated insulin levels, and in recent years scientists have proposed that insulin may contribute directly or indirectly to the development of breast cancer ... women who had the metabolic syndrome during the three to five years prior to breast cancer diagnosis had roughly a doubling of risk ... Findings also showed significant associations with elevated blood glucose levels, triglycerides and diastolic blood pressure. For diastolic blood pressure, the result was stronger, with more than a two-fold increased risk (relative risk = 2.4). Generally, for both triglycerides and glucose the relative risk was about 1.7 for all breast cancer"
• New MRI Technique Could Mean Fewer Breast Biopsies In High-risk Women - Science Daily, 6/29/09
• New Drug May Treat Triple-Negative Breast Cancer - WebMD 6/2/09
• Breast Cancer Gene Can Be Blocked By Blood Pressure Drug - Science Daily, 6/1/09 - "The gene, called AGTR1, caused normal breast cells to behave like cancer cells. This behavior was reversed by treatment with the blood pressure drug losartan. Tumors in mice that expressed AGTR1 shrunk by 30 percent eight weeks after treatment with losartan"
• Low-risk factor profile, estrogen levels, and breast cancer risk among postmenopausal women - Int J Cancer. 2008 Nov 7 - "the risk of breast cancer was markedly lower for women with a favourable risk profile than for other women and lower estrogen levels is a possible explanation"
• Sex Hormone Levels, Breast Cancer Risk, and Cancer Receptor Status in Postmenopausal Women: the ORDET Cohort - Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):169-76 - "This study provides further evidence that high levels of circulating testosterone increase the risk of developing breast cancer in postmenopausal women. The cancers that develop are mainly estrogen receptor positive. Although HER2(+) and HER2(-) breast cancers were both associated with high total testosterone, they showed opposing associations with estrogen"
• High Insulin Level Is An Independent Risk Factor For Breast Cancer - Science Daily, 12/31/08 - "women with the highest insulin levels had nearly a 1.5-fold higher risk of developing breast cancer than the women with the lowest insulin levels. Further, the investigators separately analyzed women who were not using hormone therapy and found that, in these women, those individuals with the highest insulin levels had a 2.4-fold increased risk of developing breast cancer compared to those with the lowest levels, even after accounting for multiple other breast cancer risk factors, including estrogen levels"
• Nonhormonal Treatment Regimens Improve Survival In Patients With Metastatic Breast Cancer - Science Daily, 12/23/08
• Breast Cancer Treatment Offers Better Outcome To Women With Implants - Science Daily, 12/11/08
• HER2 Levels May Aid In Treatment Selection For Metastatic Breast Cancer - Science Daily, 12/2/08
• Can Breast Cancer Disappear? - WebMD, 11/24/08
• DCIS Recurrence Rate Low in Young Women - WebMD, 9/26/08
• New Options for Breast Reconstruction - WebMD, 9/17/08
• Psychological Distress May Increase Risk of Breast Cancer - Medscape, 9/15/08 - "The team evaluated interactions between breast cancer and severe life events -- such as loss of a parent or divorce of parents before age 20, or loss of a close relative or spouse -- and mild to moderate life events -- e.g., separation from a spouse, loss of a job, an economic crisis, or severe illness in a close relative ... Multivariate analysis revealed a positive association (odds ratio, 1.62) between exposure to more than one adverse life event and breast cancer. "It wasn't enough to be exposed to one life event, a woman had to be exposed to more than one event,""
• New Vaccine Fights Breast Cancer Tumors - WebMD, 9/15/08
• Can Breast MRI Help Evaluate Cancer? - WebMD, 9/8/08
• Breast Cancer: Risk Remains Years Later - WebMD, 8/12/08
• Metformin Increases Pathologic Complete Response Rates In Breast Cancer Patients With Diabetes - Science Daily, 6/2/08 - "the pathologic complete response rates in the diabetic breast cancer patients taking Metformin was 24 percent, three times higher than the rates in diabetic patients not taking the drug, 8 percent. In the non-diabetic women, the pathologic complete response rate was 16 percent"
• Bone Drug Prevents Breast Cancer Return - WebMD, 6/2/08 - "Zometa creates a tumor-hostile environment that helps to keep cancer away, and it is very safe"
• Breast Cancer Study: No Link Between Aromatase Inhibitors and Cardiovascular Problems - Doctor's Guide, 4/24/08
• New Type Of Drug Shrinks Primary Breast Cancer Tumors Significantly In Just 6 Weeks, Study Shows - Science Daily, 4/17/08
• Synthetic Vitamin D Helps Prevent Some Breast Cancers, Animal Study Suggests - Science Daily, 4/14/08 - "daily injections of Gemini 0097 cut growth of ER-positive cancer by 60 percent in rat studies, and reduced ER-negative breast cancer by half in mice"
• New Option For Targeted Breast Cancer Therapy, Study Suggests - Science Daily, 4/4/08
• Trimming Breast Cancer Radiation Time - WebMD, 3/18/08
• High Levels Of Estrogen Associated With Breast Cancer Recurrence - Science Daily, 3/6/08
• New Anti-cancer Agent Can Overcome Resistance To Drugs, Says Study - Science Daily, 2/21/08
• Personalized Medicine Can Cut Breast Cancer Risk - Science Daily, 2/19/08
• Patients, Doctors, Overrate DCIS Risk - Science Daily, 2/12/08
• Metformin May Have Novel Role as Breast Cancer Drug - oncologystat.com - "In one recent hypothesis-generating metformin study, Dr. Josie M.M. Evans and coworkers at the University of Dundee (Scotland) evaluated roughly 11,876 patients with newly diagnosed type 2 diabetes, of whom 923 were subsequently diagnosed with cancer. The adjusted relative risk of malignancy in long-term metformin users was reduced by 44%, compared with nonusers ... In another population-based cohort study ... In another population-based cohort study, investigators at the Institute of Health Economics, Edmonton, Alta., identified 10,309 Saskatchewanians with type 2 diabetes. During an average of 5.4 years of follow-up after their diagnosis, 407 cancer-related deaths occurred. Cancer mortality was 3.5% in metformin users, 5.8% in insulin users, and 4.9% in individuals on sulfonylurea monotherapy. After adjustment in a multivariate Cox regression analysis, cancer-related mortality was 30% greater in sulfonylurea users than in metformin users. In insulin users, it was 90% higher than in metformin users" - See Metformin at OffshoreRx1.com.
• Acrylamide In Food May Increase The Risk Of Breast Cancer - Science Daily, 1/11/08 - "Acrylamide is a chemical formed when frying, roasting, grilling or baking carbohydrate-rich foods at temperatures above 120°C. Acrylamide is thus found in a number of foods, such as bread, crisps, French fries and coffee. Tobacco smoking also generates substantial amounts of acrylamide ... The risk of breast cancer doubles with a tenfold increase in the acrylamide-haemoglobin level. A tenfold increase in the acrylamide-haemoglobin level corresponds more or less to the difference measured between the women with the lowest and highest exposure"
• Breast Cancer: Know the Surgery Options - WebMD, 12/21/07
• Technology Helps Increase Breast Tissue After Partial Mastectomy - Doctor's Guide, 12/17/07
• Agent Reduces Breast Cancer Risk in Two Groups of Women - Physician's Weekly Article, 12/17/07 - "raloxifene hydrochloride reduced the risk of invasive breast cancer by 44% to 71% by blocking estrogen receptors in the breast"
• Survey Underscores Importance Of Emotional/educational Needs Among Women With Advanced Breast Cancer - Science Daily, 12/16/07
• Even Tiny Breast Tumors Can Be Aggressive And May Require Maximum Therapy - Science Daily, 12/16/07
• Drug Combination Shrinks Breast Cancer Metastases In Brain - Science Daily, 12/16/07
• Drugs Cut Bone Loss of Hormone Therapy - WebMD, 12/14/07
• Test Spots Women Who Can Skip Chemo - WebMD, 12/13/07
• Shorter Breast Cancer Treatment Works - WebMD, 12/13/07
• Studies: Many breast cancer patients can skip chemo - USATODAY.com, 12/13/07
• Staying slim improves improves breast cancer survival - USATODAY.com, 12/7/07
• Cryotherapy Offers Good Local Control of Small Breast Cancer - Doctor's Guide, 11/26/07
• Immune System May Make or Break Cancer - WebMD, 11/19/07
• Drug Found Effective In Treating, Preventing Breast Cancer - Science Daily, 11/1/07
• Extra Radiation Dose Prevents Breast Cancer Return In Young Women, Study Suggests - Science Daily, 10/29/07
• Women With Breast Cancer Have Less Dermatitis When Treated With IMRT - Science Daily, 10/28/07
• Young Women Suffering From Breast Cancer Do Not Necessarily Benefit From Chemotherapy - Science Daily, 10/11/07
• Breast Cancer Linked To Pesticide DDT, Study Suggests - Science Daily, 10/9/07
• Alcohol Amount, Not Type -- Wine, Beer, Liquor -- Triggers Breast Cancer - Science Daily, 9/27/07 - "women who drank between one and two alcoholic drinks per day increased their risk of breast cancer by 10 percent compared with light drinkers who drank less than one drink a day. The risk of breast cancer increased by 30 percent in women who drank more than three drinks a day"
• Weekly Dose Of Osteoporosis Drug Prevents Bone Loss After Breast Cancer Treatment - Science Daily, 9/18/07
• Chemotherapy May Be Culprit for Fatigue In Breast Cancer Survivors - Doctor's Guide, 9/10/07
• Low Breast Cancer Pill Use Ups Death - WebMD, 9/6/07
• Hypnosis Reduces Pain And Costs In Breast Cancer Surgery - Science Daily, 8/28/07
• Dense Breasts, Hormone Levels Are Two Separate, Independent Risk Factors For Breast Cancer - Science Daily, 8/20/07
• Newer Breast Cancer Drugs Aid Survival - WebMD, 7/24/07
• FDA Panel OKs Evista for Breast Cancer - WebMD, 7/24/07
• High Testosterone Linked to Worse Breast Cancer Prognosis - Medscape, 7/18/07
• Grapefruit link to breast cancer - BBC News, 7/16/07 - "eating just a quarter of a grapefruit daily raised the risk by up to 30% ... The fruit is thought to boost levels of oestrogen - the hormone associated with a higher risk of the disease"
• Meat, Sweets Boost Breast Cancer Risk - WebMD, 7/10/07 - "A meat-sweet diet raised the risk [of breast cancer] by 60% in postmenopausal women ... it would be prudent at the minimum to stay away from a diet heavy in meat, processed grains, sweets, and desserts"
• 'Genius Pill' Relieves Chemobrain - WebMD, 6/5/07 - "Provigil seems to boost brainpower without causing the jittery, restless feelings induced by amphetamines ... after just four weeks, women could recall faster and more accurately recognize words and pictures. By eight weeks, attention deficits improved and memory was even better" - See Modafinil at International Anti-aging Systems or OffshoreRx1.com.
• Breast cancer study: Use less radiation - USA Today, 6/3/07
• Many Factors Causing Breast Cancer Drop - WebMD, 5/3/07
• Decrease In Breast Cancer Rates Likely Reflect HRT Reduction And Saturation Of Mammography - Science Daily, 5/3/07
• Drinking 'fuels growth of tumour' - BBC News, 5/1/07
• Vaccine May Help Fight Breast Cancer - WebMD, 4/18/07
• Chemo Before Breast Cancer Surgery OK - WebMD, 4/18/07
• Strong Link Between Breast Cancer And Hormone Replacement Therapy Found - Science Daily, 4/18/07 - "At best, based on this analysis, an individual woman could reduce her individual risk of developing breast cancer by one in 60, or about 1.7 percent, if she stopped using hormones"
• Breast Cancer Vaccine Stimulates Potent Immune Response To Cancer Cells - Science Daily, 4/17/07
• MRI Proposed for Women With High Breast Cancer Risk - WebMD, 3/28/07
• High-Fat Diet Linked to Breast Cancer - WebMD, 3/20/07 - "Compared with women whose diets averaged 20% of calories from fat, women who derived roughly 40% of their calories from fat sources had a 15% increased risk for developing breast cancer"
• Switching to Aromatase Inhibitors After Tamoxifen Improves Survival - Medscape, 2/12/07
• Vinflunine/Capecitabine Combo Shows Favorable Results in Progressive Breast Cancer - Doctor's Guide, 2/8/07
• FDA OKs Breast Cancer Recurrence Test - WebMD, 2/6/07
• Hormone Drug Type Makes Survival Difference In Advanced Breast Cancer - Science Daily, 2/1/07
• Finding the Best Breast Cancer Surgeon - WebMD, 1/18/07
• Breast Density, Cancer Link? - WebMD, 1/17/07
• Test Predicts Breast Cancer Recurrence - WebMD, 12/19/06
• Low Risk of Recurrence After 5 Years in Ductal Carcinoma in Situ Lumpectomy Without Radiation - Doctor's Guide, 12/18/06
• Red meat raises breast cancer risk - MSNBC, 11/13/06 - "Women who ate more than 1½ servings of red meat per day were almost twice as likely to develop hormone-related breast cancer as those who ate fewer than three portions per week"
• New Breast Cancer Therapy Has Benefits - WebMD, 11/8/06
• Chemo Combo May Beat Breast Cancer - WebMD, 11/1/06
• Drug Combination Significantly Improves Outcomes in Breast Cancer - Medscape, 10/12/06
• Ibandronate (Bondronat) Excellent Treatment Option for Metastatic Bone Pain - Doctor's Guide, 10/3/06
• Once-Weekly Epoietin Manages Anemia in Breast Cancer Patients Receiving Chemotherapy - Doctor's Guide, 10/1/06
• New Breast Cancer Drugs Beat Tamoxifen - WebMD, 9/20/06
• Aromatase Inhibitors: A Treatment Of Choice For Advanced Breast Cancer Patients - Science Daily, 9/20/06
• Raloxifene Reduces Breast Cancer Risk in Postmenopausal Women at All Risk Levels - Doctor's Guide, 9/13/06 - "use of raloxifene was associated with a 58 percent reduction in breast cancer risk in women without a family history of the disease, and an 89 percent reduction in risk for women with a family history of breast cancer" - See raloxifene at OffshoreRx1.com.
• Cytogen Launches First Oral Liquid Formulation of Hormonal Therapy for Breast Cancer Patients - Doctor's Guide, 8/17/06
• Significant Advance in Treatment of Breast Cancer Reported - Doctor's Guide, 7/10/06
• Sequence of Therapies Is Not Associated with Improved Survival for Patients with Inflammatory Breast Cancer - Doctor's Guide, 7/4/06
• Gemcitabine Enhances Vinorelbine in Metastatic Breast Cancer - Doctor's Guide, 6/6/06
• Every-3-Week Schedule of Docetaxel Yields Higher Response Rate than Weekly Schedule - Doctor's Guide, 6/6/06
• Lapatinib Plus Capecitabine Nearly Doubles Time to Progression in Advanced Breast Cancer - Doctor's Guide, 6/4/06
• Breast MRI Can Be Cost-Effective For Some Women at High-Risk of Cancer - Doctor's Guide, 5/26/06
• Obesity Boosts Risk of Breast Cancer - WebMD, 5/22/06
• Breast Conservation a Good Option for Non-Invasive, 'Early' Breast Cancer, U-M Study Shows - Doctor's Guide, 5/4/06
• Breast Reconstruction - Medscape, 4/24/06
• Osteoporosis Drug Raloxifene Shown to Be as Effective as Tamoxifen in Preventing Invasive Breast Cancer - Doctor's Guide, 4/17/06
• Newer Chemotherapies Improve Outcomes for Some Types of Breast Cancer - Doctor's Guide, 4/12/06
• Breast Cancers: Which Need Chemo? - WebMD, 4/11/06
• Routine Breast Cancer Screening With Ultrasound Not Recommended - Doctor's Guide, 4/11/06
• Sentinel Lymph Node Surgery Appropriate for Male Breast Cancer - Doctor's Guide, 4/10/06
• Cryo-Assisted Tumor Localization Better for Partial Mastectomy - Doctor's Guide, 4/10/06
• Intraoperative Radiotherapy Boost Reduces Breast Cancer Recurrence - Doctor's Guide, 4/10/06
• Partial Breast Irradiation Successful for Ductal Carcinoma In Situ - Doctor's Guide, 4/10/06
• Paclitaxel-Bevacizumab Combination Prolongs Progression-Free Survival in Advanced Breast Cancer - Doctor's Guide, 3/23/06
• More Routine Monitoring of Bone Density, Preventive Management, May Prevent Bone Loss During Breast Cancer Therapy - Doctor's Guide, 3/23/06
• Breast Asymmetry Points to Cancer Risk - WebMD, 3/20/06
• New Drugs Added to Breast Cancer Guidelines - Doctor's Guide, 3/13/06
• Some Benign Breast Lesions Could Be Dangerous - Science Daily, 2/28/06
• Bondronat Achieving Better Outcomes in Metastatic Breast Cancer - Doctor's Guide, 2/21/06
• Emerging Treatments in Breast Cancer - Physician's Weekly, 2/20/06
• New Cancer Treatment Targets Breast Ducts - HealthDay, 2/3/06
• Liposomal Doxorubicin Plus Cyclophosphamide Shows Promise in Advanced Breast Cancer - Doctor's Guide, 2/3/06
• Regular Use Of Selective COX-2 Inhibitors Decreases Risk Of Breast Cancer - Science Daily, 1/30/06 - "a daily dose of 200 mg celecoxib reduced the risk of breast cancer by 83% and a daily dose of 25 mg rofecoxib reduced the risk of breast cancer by 64%. Regular use of non-selective COX-2 inhibitors - aspirin (325 mg), ibuprofen (200mg) and naproxen (250 mg) - also significantly reduced the risk of breast cancer, but less so than regular intake of selective COX-2 inhibitors"
• Most Don't Rebuild Breast After Cancer - WebMD, 1/27/06
• New Cutting-Edge Treatments for Breast Cancer - ABC News, 1/25/06
• Breast Cancer: Topical Estrogen Risky - WebMD, 1/25/06
• Fatigue and Breast Cancer Survivors - Doctor's Guide, 1/9/06
• Shorter Radiation for Breast Cancer - WebMD, 1/4/06
• FDA Clears Xoft's Axxent Electronic Brachytherapy System for Treatment of Breast Cancer - Doctor's Guide, 1/4/06
• Interim Analysis of Phase 3 Study Shows Taxotere (docetaxel)-Based Regimens with Herceptin (trastuzumab) Significantly Improved Disease-Free Survival in Women with Early-Stage HER2-Positive Breast Cancer - Doctor's Guide, 12/16/05
• Radiotherapy after Lumpectomy Saves Lives - Doctor's Guide, 12/16/05
• Breast Cancer Radiation Ups Survival - WebMD, 12/15/05
• About Half of Women Facing Breast Cancer Surgery Require Psychiatric Intervention - Doctor's Guide, 12/13/05
• Pilot Study Shows Abraxane Safe and Effective in Sequence with Dose-Dense Doxorubicin and Cyclophosphamide - Doctor's Guide, 12/13/05
• Dose-Dense Chemotherapy Found More Effective than Standard Delivery Times - Doctor's Guide, 12/13/05
• Panel Revises Breast Cancer Treatment Guidelines - ABC News, 12/13/05
• Dose Dense Doxorubicin-Docetaxel Combination Comparable to Standard Doxorubicin-Cyclophosphamide-Docetaxel Regimen - Doctor's Guide, 12/13/05
• Taxotere/Cyclophosphamide Offers Greater Disease-Free Survival for Early Stage Breast Cancer Patients - Doctor's Guide, 12/13/05
• Taxane-Based Breast Cancer Treatment Cost-Effective Compared to 5-fluorouracil-Based Therapy - Doctor's Guide, 12/13/05
• Neoadjuvant Docetaxel, Doxorubicin and Capecitabine Used in Women with Locally Advanced or Inflammatory Disease - Doctor's Guide, 12/13/05
• Ritalin Conjugate Used to Treat "Chemo-Brain" in Breast Cancer Patients - Doctor's Guide, 12/13/05
• Fewer Breast Cancer Patients to Get Chemo - Intelihealth, 12/12/05
• Low-dose Chemotherapy Plus Antiangiogenesis Drug Has Activity In Advanced Breast Cancer - Doctor's Guide, 12/12/05
• Bortezomib (Velcade) and Capecitabine (Xeloda) in Combination Generally Safe for Patients with Metastatic Breast Cancer - Doctor's Guide, 12/9/05
• Radiation Therapy Greatly Reduces Risk of Local Recurrence, Does Not Affect Overall Survival after Ductal Carcinoma in Situ - Doctor's Guide, 12/9/05
• Metronomic Therapy Appears Useful in Advanced Breast Cancer Patients - Doctor's Guide, 12/8/05
• Women with Breast Cancer Face Increased Risk of Developing a Second Cancer - Doctor's Guide, 12/8/05
• Dose-dense Chemotherapy For Early Breast Cancer Found Safe, Similar To Standard Regimen - Science Daily, 12/7/05
• Study Demonstrates Role Of Exercise In Modifying Melatonin Levels; Increase Believed To Offer Breast Cancer Protection - Science Daily, 12/3/05
• Breast CT More Comfortable, May Detect Tumors Better - Doctor's Guide, 12/2/05
• Alcohol Raises Risk of Specific Breast Cancers - WebMD, 11/1/05
• Ibandronate Lessens Bone Pain in Metastatic Breast Cancer - Doctor's Guide, 10/31/05
• Post-Mastectomy Radiation May Cause Skin Toxicity and Pain - Doctor's Guide, 10/31/05
• Clodronate Shows Protective Skeletal Effect in Primary Breast Cancer - Doctor's Guide, 10/31/05
• Psychological and Social Impacts of Contralateral Prophylactic Mastectomies - Doctor's Guide, 10/29/05
• Magnetic Resonance Imaging Scans Find Missed Breast Lesions in Lumpectomy Candidates - Doctor's Guide, 10/21/05
• Targeted Drug May Change Breast Cancer Care - WebMD, 10/19/05
• Breast Cancer Diagnosis Does Not Mean Breast Implants Have to Go - Doctor's Guide, 10/19/05
• Doctors Question Use of Aromatase Inhibition after 5 Years of Tamoxifen in Most Breast Cancer Patients - Doctor's Guide, 10/19/05
• Targeted Radiation Cuts Breast Cancer Relapse - WebMD, 10/18/05
• Digital Breast Screening Best for Many Women - WebMD, 9/16/05
• How hormones can affect breast cancer risk - MSNBC, 9/9/05 - "Research also consistently links high levels of the hormone insulin and insulin-like growth factors with increased rates of breast cancer, at least after menopause"
• Obese Breast Cancer Patients: How Much Chemo? - WebMD, 8/23/05
• Less Extensive Biopsy Method Helps Diagnose Cancer Progression of Large Breast Tumors - Doctor's Guide, 8/23/05
• Many Choose Aggressive Breast Cancer Surgery Despite Options - Doctor's Guide, 8/19/05
• Benign breast lumps don't raise long-term risk - MSNBC, 7/20/05
• Bisphosphonates - a Successful Treatment for Metastatic Bone Disease Associated With Breast Cancer - Doctor's Guide, 7/15/05
• Interleukin 10 May Have Protective Effect Against Breast Cancer - Doctor's Guide, 6/7/05
• Finely tuned diagnoses and targeted drugs create optimism about surviving breast cancer - USNews.com, 6/13/05
• Breast Cancer Easier To Miss In Women On HRT - CBS 2 Chicago, 5/25/05 - "found an increased chance that cancer may be missed among women on HRT. That may be because some of their breast tissue is more dense, making the cancer more difficult to find"
• Statin Use Linked to 51% Reduction in Breast Cancer - Medscape, 5/20/05 - "The beneficial effect is seen in more than four years of statin use ... In both the prostate and lung cancer studies, there was a 48% to 54% risk reduction in cancer associated with statin use" - See Lipitor at SuperSaverMeds.com.
• Doxorubicin/Cyclophosphamide as Effective as Doxorubicin/Docetaxel (AT) for Early-stage Breast Cancer - Doctor's Guide, 5/16/05
• Low-Fat Diet May Cut Return of Breast Cancer - WebMD, 5/16/05 - "At five years, less than 10% of those on the low-fat diet had their cancer recur. Twelve percent of the women who continued on their usual diet had cancer recurrence during this time. This translates to about a 24% reduction in risk"
• Regular Alcohol Intake Ups Breast Cancer Risk - WebMD, 5/16/05 - "Women who drank a glass or two a day faced a 21% increased risk of breast cancer ... Those who drank more than two drinks a day were 37% more likely to develop breast cancer ... the risk was much greater in menopausal women"
• Breast Cancer Treatments Up Long-Term Survival - WebMD, 5/12/05
• Hormone May Cut Breast Cancer Cells' Spread - WebMD, 5/3/05
• Breast-cancer Risk Linked To Exposure To Traffic Emissions At Menarche, First Birth - Science Daily, 4/30/05 - "higher exposure around the time of first menstruation to polycyclic aromatic hydrocarbons (PAHs), potential carcinogens found in traffic emissions, was associated with increased risk of premenopausal breast cancer"
• Herceptin (Trastuzumab) Appears to Offer Significant Improvement in Disease-Free Survival for Women With Early-Stage HER2-Positive Breast Cancer - Doctor's Guide, 4/28/05
• Drug helps fight return of breast cancer - MSNBC, 4/26/05
• Herceptin (Trastuzumab) Combined With Chemotherapy Improves Disease-Free Survival for Patients With Early-Stage Breast Cancer - Doctor's Guide, 4/26/05
• New Recommendations for Aromatase Inhibitor Therapy for Breast Cancer - Doctor's Guide, 4/20/05
• Pregnancy Hormone May Prevent Breast Cancer - WebMD, 4/19/05
• Multimodal Therapy Effective for Women With Limited Breast Cancer Recurrence - Doctor's Guide, 4/19/05
• Breast Cancer Therapy Involves More Than Just Following Guidelines - Doctor's Guide, 4/19/05
• Palonosetron (Aloxi) Reduces Impact of Chemotherapy-induced Nausea and Vomiting on Daily Life in Women With Breast Cancer - Doctor's Guide, 4/19/05
• Surgeon's Location and Affiliations Linked With Women's Surgical Options for Breast Cancer - Doctor's Guide, 4/15/05
• Increased Surveillance Needed After Benign Breast Biopsies - Doctor's Guide, 4/15/05
• Avastin (Bevacizumab, rhuMAb-VEGF) Plus Chemotherapy Appears to Produce Significant Benefit in First-Line Metastatic Breast Cancer - Doctor's Guide, 4/15/05
• Unexpected Benefit Seen in Treating HER-2 Breast Cancer With New Preoperative Drug Combo - Doctor's Guide, 3/30/05
• Ablative Modalities Show Promise in Breast Cancer Treatment - Doctor's Guide, 3/28/05
• Results Encouraging for Cryoablation of Small Breast Tumors - Doctor's Guide, 3/28/05
• Aromatase Inhibitors Show Promise As Adjuvant Therapy - Doctor's Guide, 3/28/05
• Study Shows Acrylamide In Baked And Fried Foods Does Not Increase Risk Of Breast Cancer In Women - Science Daily, 3/24/05
• Cryoablation Shows Promise in Managing Fibroadenomas - Doctor's Guide, 3/22/05
• Small Lesions on Magnetic Resonance Imaging Usually Benign - Doctor's Guide, 3/22/05
• Biopsy Type Does Not Affect Risk of Micrometastasis in Patients With Breast Cancer - Doctor's Guide, 3/21/05
• Breast Cancer Radiation Has Become Safer - WebMD, 3/15/05
• Postmenopausal Breast Cancer Survivors at Increased Risk for Bone Fractures - Doctor's Guide, 3/14/05
• Closing In On A Vaccine For Breast Cancer - Science Daily, 3/14/05
• Underactive Thyroid Cuts Breast Cancer Risk - WebMD, 2/14/05 - "an underactive thyroid was shown to protect against developing breast cancer. The study also showed that women who developed breast cancer and who had an underactive thyroid had a less aggressive disease compared with women with a normally functioning thyroid"
• Women With Hypothyroidism Appear to Have Lower Risk of Breast Cancer - Doctor's Guide, 2/14/05
• Herceptin With Weekly Taxol and Platinum Show Positive Results in First-Line Treatment in HER2-Positive Metastatic Breast Cancer - Doctor's Guide, 2/3/05
• Benefit Seen With Zoledronic Acid for Prevention of Skeletal Complications or Bone Loss in Women With Breast Cancer - Doctor's Guide, 2/3/05
• Magnetic Resonance Imaging Better Than Mammography or Ultrasound for Women at High Risk for Breast Cancer - Doctor's Guide, 1/31/05
• Multinational Study Finds Patient Satisfaction Following Cryoablation of Benign Breast Tumors to be 92% - Doctor's Guide, 1/20/05
• FDA Issues Approvable Letter for Bonefos (Clodronate) for Adjuvant Treatment of Breast Cancer - Doctor's Guide, 1/7/05
• Some Breast Cancers May Not Need Chemo - WebMD, 12/29/04
• Breast Reconstruction Safe in the Long Term - WebMD, 12/22/04
• The Role of the Aromatase Inhibitors in Early-Stage Breast Cancer: An Expert Interview With Eric Winer, MD - Medscape, 12/20/04
• Sentinel Node Biopsy Reduces Morbidity - Doctor's Guide, 12/17/04
• Clodronate Reduces Morbidity Even Among Patients With Breast Cancer Relapse - Doctor's Guide, 12/14/04
• Menstrual Cycle Phase Does Not Affect Breast Cancer Surgery Outcome - Doctor's Guide, 12/14/04
• GEMOX Treatment Controls Disease in Half of Women With Advanced Breast Cancer - Doctor's Guide, 12/14/04
• Acellular Tissue Matrix Used for Immediate Breast Reconstruction - Doctor's Guide, 12/14/04
• Darbepoetin Found Similar to Epoetin in More Convenient Regimen for Treating Anemia in Breast Cancer - Doctor's Guide, 12/13/04
• Sentinel Node Biopsy Proves 97% Accurate in Largest Randomized Trial to Date - Doctor's Guide, 12/13/04
• Pegfilgrastrim Prevents Chemotherapy-Associated Febrile Neutropenia - Doctor's Guide, 12/13/04
• Pre-Menopausal Women With Advanced Breast Cancer Treated With Goserelin/Anastrozole Therapy - Doctor's Guide, 12/13/04
• Erythropoetin Improves Quality of Life, Not Cognition in Breast Cancer Patients - Doctor's Guide, 12/13/04
• Test Could Spare Women From Chemotherapy - WebMD, 12/10/04
• Arthritis Drug May Prevent Breast Cancer - WebMD, 12/10/04
• Intensive Chemotherapy, Mastectomy Improve Outcomes in Inflammatory Breast Cancer - Doctor's Guide, 12/10/04
• Taxanes May Protect against Chemotherapy-Related Amenorrhea - Doctor's Guide, 12/10/04
• New Test Better Predicts Breast Cancer Spread - WebMD, 12/9/04
• Boosting Tumor Suppressor Gene Helps Reduce Breast Cancer Tumor Size Prior to Surgery - Doctor's Guide, 12/9/04
• Estrogen-Positive Breast Cancer Patients Have Better Outcomes With Chemoendocrine Therapy Rather Than Tamoxifen Alone - Doctor's Guide, 12/9/04
• Taxane-Refractory Breast Cancer Responds to Nanoparticle Albumin Paclitaxel (Abraxane) - Doctor's Guide, 12/9/04
• Zoledronic Acid Counteract Treatment-Related Bone Loss - Doctor's Guide, 12/9/04
• Hormonal Therapy Alone May Not Be Sufficient Treatment in Breast Cancer - Doctor's Guide, 12/8/04
• New Molecular Classification Of Breast Cancer Predicts Response To Chemotherapy - Doctor's Guide, 12/8/04
• Advance in breast cancer treatment - BBC News, 12/8/04
• MRI Shows Breast Tumors, but Biopsy Needed - WebMD, 12/7/04
• Breast Magnetic Resonance Imaging Moderately Useful For Detecting Breast Cancer, But Does Not Eliminate Need For Biopsy - Doctor's Guide, 12/7/04
• Magnetic Resonance Detects Breast Cancers Not Observed With Mammography - Doctor's Guide, 12/3/04
• Breast Conserving Therapy Safe For Hereditary Breast Cancer - Science Daily, 12/2/04
• Low levels of HDL cholesterol linked to breast cancer risk - US News, 12/1/04 - "Women with high HDL levels were 25 percent less likely to get postmenopausal breast cancer than women with low HDL cholesterol. The difference was even bigger for women who were overweight"
• Osteoporosis Drug May Cut Breast Cancer Risk - WebMD, 11/30/04
• TRAM Flap Procedure Restores Breasts Of Cancer Patients - Science Daily, 11/23/04
• Breast Cancer Gene: Can the Breast Be Saved? - WebMD, 11/22/04
• Breast Conserving Treatment Reasonable Option for Women With Hereditary Breast Cancer - Doctor's Guide, 11/22/04
• Women Appear to Prefer Endocrine Treatment With Zoladex (Goserelin) to Chemotherapy for Treatment of Early Breast Cancer - Doctor's Guide, 11/16/04
• New Breast Cancer Drugs May Beat Tamoxifen - WebMD, 11/15/04
• Aromatase Inhibitors Now Recommended as Adjuvant Therapy for Postmenopausal Women With Early Breast Cancer - Doctor's Guide, 11/15/04
• Arthritis Drug May Shrink Breast Cancers - WebMD, 11/5/04
• Test Predicts Breast Cancer Spread - WebMD, 11/2/04
• Epoetin Alfa Provides Faster, Stronger Response in Anemic Patients at Lower Cost Than Darbepoetin - Doctor's Guide, 11/1/04
• New Radiotherapy Regime Benefits Young Women With Breast Cancer - Doctor's Guide, 10/26/04
• Fertility an Issue for Breast Cancer Patients - WebMD, 10/14/04
• Blood Test May Help Set Breast Cancer Treatment - Doctor's Guide, 10/12/04
• Mammograms Not as Reliable for Younger Women - WebMD, 10/5/04
• Magnetic Resonance Imaging Better Than Mammography for Detecting Additional Disease in Women With Breast Cancer - Doctor's Guide, 9/28/04
• Support Groups May Not Beat Breast Cancer - WebMD, 9/28/04
• Obesity Raises Breast Cancer Death Risks - WebMD, 9/21/04
• Immediate Breast Reconstruction After Mastectomy Does Not Delay Chemotherapy - Doctor's Guide, 9/21/04
• New Breast Cancer Vaccine Passes First Hurdle - WebMD, 9/14/04
• High-Risk Women: MRI Shows More Breast Cancer - WebMD, 9/14/04
• When Mammography Isn’t Enough - Physician's Weekly, 9/6/04
• Breast Cancer Patients May Not Need Radiation - WebMD, 9/1/04
• Study Finds Immune Therapy For Metastatic Breast Cancer Possible - Science Daily, 9/1/04
• Lifestyle May Affect Mammogram Accuracy - WebMD, 8/26/04
• Tumor Cell Levels in Blood Predict Success of Advanced-stage Breast Cancer Treatment - Doctor's Guide, 8/19/04
• Speedier Look at Advanced Breast Cancer - WebMD, 8/18/04
• The Telomere Crisis: A Crucial Stage In Breast Cancer - Science Daily, 8/11/04
• Experience Counts in Breast Cancer Surgery - WebMD, 8/9/04
• High-Carb Diet Linked to Breast Cancer - WebMD, 8/6/04
• Study Links High Carbohydrate Diet To Increased Breast Cancer Risk - Science Daily, 8/6/04 - "those who derived 57 or more percent of their total energy intake from carbohydrates incurred a risk of breast cancer 2.2 times higher than women with more balanced diets"
• Ellence (Epirubicin) Based Chemotherapy Regimen Has Survival Benefits With Low Risk Of Adverse Cardiac Events - Doctor's Guide, 8/3/04
• Emerging Research May Elucidate Treatment Approaches for Breast Cancer Patients with Bone Metastases - Doctor's Guide, 7/30/04
• Emerging Cytotoxic Therapies, Combinations Showing Promise in Refractory, Resistant Breast Cancer - Doctor's Guide, 7/29/04
• MRI Beats Mammogram for Women at High Risk - WebMD, 7/28/04
• Breast Cancer Research Has Several Promising Treatments in the Pipeline - Doctor's Guide, 7/28/04
• CD-ROM Helps Women Check Breast Cancer Risk - WebMD, 7/27/04
• Efaproxiral May Extend Survival, Improve Quality of Life in Breast Cancer Patients with Brain Metastases - Doctor's Guide, 7/27/04
• New Options for Breast Cancer - WebMD, 7/22/04
• Alternate Technologies Could Save More Women's Lives - Doctor's Guide, 7/22/04
• Brachytherapy May Save Breast, Decrease Treatment Time - Doctor's Guide, 7/22/04
• Ablation Therapy May Destroy Breast Cancer Without Scarring - Doctor's Guide, 7/22/04
• Breastfeeding and Cancer in High-Risk Women - WebMD, 7/20/04
• Aggressive Breast Cancer Linked to Virus - WebMD, 7/12/04
• Balloon Brachytherapy Appears Acceptable as Adjuvant Breast Cancer Therapy in Select Patients After Lumpectomy - Doctor's Guide, 6/17/04
• Women Facing 'Crisis' in Mammographies - WebMD, 6/10/04
• Trial Confirms Efficacy of Weekly Paclitaxel for Metastatic Breast Cancer - Doctor's Guide, 6/10/04
• Adding Carboplatin to Paclitaxel and Trastuzumab Improves Response Rates in HER-2 Positive Breast Cancer - Doctor's Guide, 6/9/04
• Survival Advantage Seen With Gemcitabine/Paclitaxel (Gemzar/Taxol) Compared With Gemcitabine Alone for Treatment of Metastatic Breast Cancer - Doctor's Guide, 6/8/04
• Long-Term Raloxifene Associated With Halving of Breast-Cancer Risk in Post-menopausal Women - Doctor's Guide, 6/8/04
• Oral Bisphosphonate Prolongs Survival in Patients With Breast Cancer - Doctor's Guide, 6/7/04
• Osteoporosis Drug May Prevent Breast Cancer - WebMD, 6/7/04
• Cardiotoxicity Limited in Liposomal Doxorubicin-Trastuzumab Combination Therapy - Doctor's Guide, 6/6/04
• Pegylated Liposomal Doxorubicin-Docetaxel Combination Is Promising First-Line Treatment in Patients With Metastatic Breast Cancer - Doctor's Guide, 6/3/04
• Breast Reduction Diminishes Breast Cancer in High-Risk Women - Doctor's Guide, 6/1/04
• Mammograms Less Accurate in Obese Women - WebMD, 5/24/04
• Docetaxel, Platinum, Plus Trastuzumab Effective in HER2-Positive Advanced Breast Cancer - Medscape, 5/19/04
• Obesity Increases Breast Cancer Risk - WebMD, 5/17/04
• Cryosurgery Successful At Treating Some Early-Stage Breast Cancer - Doctor's Guide, 5/6/04
• Cholesterol Drugs: Cancer Fighters? - WebMD, 4/26/04 - "taking statins appeared to decrease the risk of breast cancer by 30% in postmenopausal women"
• Concurrent Chemo and Radiation Therapy Appears Safe and Effective in Patients with Early-Stage Breast Carcinoma - Doctor's Guide, 4/14/04
• BRCA-Positive Women May Need More Mammograms - WebMD, 4/12/04
• New Treatment May Zap Early Breast Cancers - Doctor's Guide, 3/30/04
• Ultrasound-Guided Radiofrequency Ablation Helpful in Small Breast Cancers - Medscape, 3/30/04
• Breast Cancer Effects on Physical, Emotional and Psychological Wellbeing Remain Up to 10 Years Later - Doctor's Guide, 3/23/04
• Early Breast Cancer Growth Tough To Treat - Intelihealth, 3/22/04
• Breast Conservation Surgery Safe for Patients With BRCA Mutations - Doctor's Guide, 3/22/04
• Local Excision and Mastectomy Have Equal Survival Rates for Ductal Carcinoma in Situ - Doctor's Guide, 3/22/04
• Gemcitabine-Epirubicin-Paclitaxel Effective as Primary Chemotherapy Stage II-IIIA Operable Breast Cancer - Doctor's Guide, 3/22/04
• Preoperative Chemotherapy Extends Breast Conservation Surgery, Expedites Finding Most Effective Agents for Patients' Cancer Types - Doctor's Guide, 3/22/04
• Treatment for Women With Late-Stage Breast Cancer More Effective, Less Costly With Fluorescence In Situ Hybridization Diagnostic Technology - Doctor's Guide, 3/22/04
• Menopause Changes Density of Breast Tissue and May Complicate Mammography Readings - Doctor's Guide, 2/18/04
• Breast Self-Examination Does Not Reduce Breast Cancer Mortality - Doctor's Guide, 3/18/04
• Breast Conservation Surgery Safe With BRCA1 Breast Cancer - Medscape, 3/18/04
• Wine, Fat Intake Linked to Breast Cancer - WebMD, 3/17/04 - "women who drank about 1.5 glasses of wine a day were twice as likely to develop breast cancer compared with women who drank less ... drinking women can mitigate this risk by taking a multivitamin Containing folic acid every day ... women who gain 20 to 30 pounds after high school have a 40% increase in breast cancer risk"
• Women Maintaining Younger-Looking Breasts - WebMD, 3/17/04
• Measure Estrogen Receptor Status in DCIS - Doctor's Guide, 3/15/04
• New Breast Cancer Guidelines Include Changes to Adjuvant Therapy in Invasive Disease - Doctor's Guide, 3/15/04
• Exemestane After Tamoxifen May Improve Disease-Free Survival for Postmenopausal Women with Primary Breast Cancer Over Tamoxifen Alone - Doctor's Guide, 3/10/04
• Problems Linger After Breast Cancer Treatment - WebMD, 3/2/04
• Weight Gain May Increase Breast Cancer Risk - WebMD, 2/26/04
• Anaemia Significant Problem in Early Breast Cancer Prior To, During Chemotherapy - Doctor's Guide, 2/16/04
• Nipple-Sparing Mastectomy Is Possible - WebMD, 2/12/04
• Nipple-Sparing Mastectomy Reasonable Option for Carefully Screened Patients - Doctor's Guide, 2/10/04
• Computer-Aided Mammograms No Better - WebMD, 2/3/04
• HRT Raises Breast Cancer Recurrence Risk - WebMD, 2/2/04
• Promising Early Results with First-Line Gemcitabine-Epirubicin-Paclitaxel Chemotherapy in Metastatic Breast Cancer - Doctor's Guide, 1/27/04
• Zoledronate Appears More Effective Than Pamidronate in Breast Carcinoma Patients With At Least One Osteolytic Lesion - Doctor's Guide, 1/8/04
• Whole-Breast Irradiation Improves Cancer Survival - Physician's Weekly, 1/5/04
• Less Aggressive Breast Cancer Surgery OK - WebMD, 12/29/03
• Breast Cancers Are Commonly Undertreated - WebMD, 12/15/03
• More Than Half of Early Stage Breast Cancer Patients May Not Receive Full Recommended Dose of Chemotherapy - Doctor's Guide, 12/15/03
• Emend (Aprepitant) Significantly Improved Control of Chemotherapy-Induced Nausea and Vomiting in both Women and Men - Doctor's Guide, 12/10/03
• Breast-Conserving Surgery Produces Survival Rate Similar to Mastectomy for Paget's Disease Confined to Nipple-Areolar Area - Doctor's Guide, 12/8/03
• TAC Regimen Superior to FAC for Early Breast Cancer - Medscape, 12/8/03
• Post-Surgical Breast Reconstruction Also Safe for Women With More Advanced Disease - Doctor's Guide, 12/8/03
• Endocrine Therapy A Better Choice for Estrogen-Positive Tumors? - Doctor's Guide, 12/8/03
• Weekly Combination Therapy Safe for HER2+ Breast Cancer - Medscape, 12/5/03
• Lumpectomy for Large Breast Cancers? - WebMD, 12/5/03
• 2 Opinions Help Breast Cancer Diagnosis - WebMD, 12/5/03
• Gefitinib (Iressa, Zd1839) Demonstrates Early Promise in Advanced Breast Cancer - Doctor's Guide, 12/5/03
• Weekly Chemotherapy Schedule Safer Than Three-Week Schedule - Doctor's Guide, 12/5/03
• Contrast-Enhanced Magnetic Resonance Imaging Accurately Predicts Breast Cancer Response to Neoadjuvant Chemotherapy - Doctor's Guide, 12/5/03
• Pre-Surgical Chemotherapy Plus Breast-Conserving Surgery Has High Success Rate - Doctor's Guide, 12/5/03
• Navelbine-Herceptin Combo Appears Safe and Effective as First-Line Treatment For HER2-Positive Breast Cancer - Doctor's Guide, 12/5/03
• Accelerated Chemotherapy Regimen Improves Survival in Younger Women - Doctor's Guide, 12/4/03
• Women Prefer Goserelin over Standard Chemotherapy - Doctor's Guide, 12/4/03
• Breast Scanner May Find Cancer Earlier - WebMD, 12/4/03
• Drug Switch Staves Off Breast Cancer - WebMD, 12/3/03
• New Computerized Tool Predicts Chance of Breast Cancer's Spread - Doctor's Guide, 12/3/03
• Surgery Without Radiation Inadequate for Ductal Carcinoma In Situ, Study Reveals - Doctor's Guide, 12/4/03
• Etanercept Has Potential For Treating Metastatic Breast Cancer - Doctor's Guide, 11/24/03
• Alcohol May Increase Breast Cancer Risk - WebMD, 11/18/03
• Young Breast Cancer Patients Need Long-Term Follow-Up After Lumpectomies - Doctor's Guide, 11/6/03
• Women Diagnosed With Breast Cancer Should Stop HRT - Medscape, 11/3/03
• Breast Conservation Linked to Higher Long-term Risk of Local Breast Cancer Recurrence Than Mastectomy - Medscape, 11/3/03
• Early Lumpectomy Doesn't End Cancer Risk - WebMD, 11/3/03
• Breast Cancer Vaccine Shows Promise - WebMD, 10/28/03
• Smoking Cessation Confers Survival Advantage for Breast Cancer Patients - Doctor's Guide, 10/31/03
• Radiation Therapy Safe Before or After Breast Reconstruction - Doctor's Guide, 10/31/03
• Whole-Breast Irradiation May Offer Long-Term Benefits - Doctor's Guide, 10/31/03
• Diet High in Saturated Fat May Raise Risk of Breast Cancer - Doctor's Guide, 10/30/03
• Breast Cancer Vaccine Can Induce Long-term Immunity - Medscape, 10/25/03
• Breast Reconstruction OK Before Radiation - WebMD, 10/22/03
• Zoledronic Acid More Effective Than Pamidronate in Breast Carcinoma or Multiple Myeloma Patients With Bone Metastases - Doctor's Guide, 10/22/03
• Too Many Breast Cancer Tests? - WebMD, 10/21/03
• Pegfilgrastim Comparable in Safety to Filgrastim, Yet Allows More Convenient Dosing - Doctor's Guide, 10/13/03
• Two Adjuvant Treatments for High-Risk Breast Cancer Negatively Initially Affect Health-Related Quality of Life - Doctor's Guide, 10/7/03
• New Method Makes Mammography Better - WebMD, 9/30/03
• Gefitinib (Iressa) Shown to Prolong Survival, Improve Quality of Life in Women with Recurrent Metastatic Breast Cancer - Doctor's Guide, 9/29/03
• Tegafur-uracil (UFT) Plus Surgery Outperforms Surgery Alone in Node-negative Breast Cancer - Doctor's Guide, 9/29/03
• Does Stress Cause Breast Cancer? - WebMD, 9/24/03
• Hormone Therapy Said Cutting Death Rate From Prostate, Breast Cancer In Europe - Doctor's Guide, 9/23/03
• Laser Treatment Helpful in Postmastectomy Lymphedema - Medscape, 9/16/03
• Potential Relief from Fatigue in Breast Cancer Treatment - Physician's Weekly, 9/1/03 - "fatigued survivors had T-cell numbers that were 31% higher than those of non-fatigued survivors. Conversely, the two groups did not differ in the number of other types of immune cells"
• Contrast Digital Mammography Improves Mammography Results - Doctor's Guide, 8/26/03
• Focused Breast-Cancer Radiation Effective - WebMD, 8/19/03
• Obesity, Estrogen Linked to Breast Cancer - WebMD, 8/19/03
• Pregnancy After Breast Cancer Doesn't Increase Risks of Dying - WebMD, 8/11/03
• Sentinel-Node Biopsy Accurately Screens for Axillary Node Metastasis in Breast Cancer Patients - Doctor's Guide, 8/7/03
• Ductal Lavage Helps Determine Best Approach in Patients at High Risk for Breast Cancer - Doctor's Guide, 8/7/03
• Platinum Compounds May Become Adjuvant Therapy for Breast Cancer - Doctor's Guide, 8/7/03
• Breast-Preserving Therapy Effective for Metaplastic Breast Carcinoma - Doctor's Guide, 8/6/03
• Intensive Therapy Possible Alternative to Surgery for Breast Cancer - Doctor's Guide, 8/6/03
• Two New Antiemetics Help Control Chemotherapy-Induced Emesis - Doctor's Guide, 8/6/03
• Exemestane an Alternative for Neoadjuvant Treatment of Breast Cancer in Postmenopausal Women - Doctor's Guide, 8/5/03
• Epoetin Alpha Improves Quality Of Life And Functionality Of Breast Cancer Patients - Doctor's Guide, 8/5/03
• Breast Cancer Risk Increases with Consumption of Red Meat, Dairy Products - Doctor's Guide, 7/28/03 - "derived from the Nurses' Health Study (NHS) II ... total fat intake during premenopausal years was not associated with the risk of breast cancer. However, a significant association was found between animal fat intake and breast cancer risk"
• Additional Chemotherapy and Stem-Cell Transplantation Does Not Improve Outcome for Breast-Cancer Patients - Doctor's Guide, 7/21/03
• High-Fat Diet, Breast Cancer Linked - CBS News, 7/17/03 - "those who average more than 90 grams of fat a day have roughly double the risk of those who eat just 37 grams" - That's another area that hasn't been fully researched regarding the Atkin's diet.
• Radiotherapy After Excision Reduced Incidence of Ipsilateral Ductal Carcinoma in Situ, Tamoxifen Therapy Did Not - Doctor's Guide, 7/17/03
• Three New Studies Support MRI for Breast Cancer Detection - Physician's Weekly, 7/14/03
• Trend in Omitting Radiation Therapy in Breast Cancer Patients Exponentially Increases Relative Mortality Risk - Doctor's Guide, 7/3/03
• Studies challenge breast cancer treatment - USA Today, 7/2/03
• Trastuzumab Therapy Recommended for Breast Cancer Patients with HER-2 Overexpression - Doctor's Guide, 6/27/03
• Extra Checks For Breast Cancer In Pregnancy Needed - Doctor's Guide, 6/20/03
• New Contrast Agent Reveals Otherwise Undetectable Lymph-Node Metastases - Medscape, 6/18/03
• Early Breast Cancers Caught by MRI - WebMD, 6/16/03
• Study Links Common Indicator Of Early Puberty To Obesity, Breast Cancer - Doctor's Guide, 6/16/03
• Sequential Adjuvant Chemotherapy Does Not Increase Survival in Operable Breast Cancer Patients - Doctor's Guide, 6/12/03
• Male Breast Cancer Detected Later - WebMD, 6/6/03
• Study Of Twins Suggests Early Puberty Strongly Influences Age At Diagnosis Of Breast Cancer In Genetically - Doctor's Guide, 6/6/03
• Breast Cancer in Men Often Underestimated and Under-treated - Doctor's Guide, 6/4/03
• Magnetic Resonance Imaging Plus Mammograms Best for Women at High-Risk for Breast Cancer - Doctor's Guide, 6/3/03
• Magnetic Resonance Imaging Outperforms Mammography and Ultrasound in Detecting Breast Cancer in High-Risk Women - Doctor's Guide, 6/3/03
• High HER-2/neu Level Indicates Poor Prognosis in Breast Cancer Patients - Doctor's Guide, 6/3/03
• Is MRI Better Than Mammography? - WebMD, 6/2/03
• Gemcitabine, Epirubicin, Paclitaxel Combination No Better than 5-Fluorouracil, Epirubicin, Cyclophosphamide in Metastatic Breast Cancer - Doctor's Guide, 6/2/03
• BMS-247550 Demonstrates Activity In Metastatic Breast And Non-Small Cell Lung Cancers - Doctor's Guide, 6/2/03
• Magnetic Resonance Imaging Finds Missed Breast Cancers, but At a High Cost in False Positives - Doctor's Guide, 6/2/03
• Combining Two Standard Drugs Effective for Salvage Treatment in Metastatic Breast Cancer - Doctor's Guide, 6/2/03
• Gemzar (Gemcitabine) Combination Showed Significant Efficacy Advantage In Breast Cancer Study - Doctor's Guide, 6/2/03
• MRIs Help Detect Breast Lumps - CBS News, 5/30/01
• Tamoxifen Alone More Effective than With Ovarian Ablation for Node Negative Breast Cancer - Doctor's Guide, 6/1/03
• Adjuvant Chemotherapy Just as Effective for Older as Younger Breast Cancer Patients - Doctor's Guide, 6/1/03
• Mitoxantrone Linked to Hemopathy after Breast Cancer - Doctor's Guide, 6/1/03
• Tissue Engineered Skin Effective for Breast Wound Salvage - Doctor's Guide, 5/28/03
• Link Eyed Between Beef And Cancer - CBS News, 5/21/03 - "beef cattle are given growth hormones to make them fatter faster, to save money ... questions are being raised about one of the most widely-used hormones, Zeranol, a synthetic estrogen implanted in cattle. A series of tests done for the Pentagon show a possible link between breast cancer and Zeranol"
• Cancer Society Endorses Mammograms, Moves Away From Self-Exams - Intelihealth, 5/16/03
• 3D Mammography Promising As Next Breast Screening Technique - Doctor's Guide, 5/8/03
• Mammograms Read By Specialists Save Patients' Time And Money - Doctor's Guide, 5/8/03
• MRI Works for Breast Cancer Screening - WebMD, 5/7/03
• Magnetic Resonance Imaging Accurate In Detecting Residual Disease Following Lumpectomy - Doctor's Guide, 5/7/03
• Magnetic Resonance Imaging Should Be Considered For Breast Screening Of High Risk Women - Doctor's Guide, 5/6/03
• Whole Body Positron Emission Tomography Accurate in Detecting Breast Cancer Spread - Doctor's Guide, 5/5/03
• New Guidewire Converts Non-Palpable Breast Lesions Into Palpable Ring for Surgical Removal - Doctor's Guide, 5/5/03
• Single Catheter Balloon Provides Five-Day Radiation Treatment for Breast Cancer - Doctor's Guide, 5/5/03
• Ultrasound Core Breast Biopsy Shown to Negate Need for Excisional Breast Biopsy for Large Patient Population - Doctor's Guide, 5/5/03
• Ductal Lavage Useful for Women at High Risk of Breast Cancer - Medscape, 5/2/03
• Divided Vinorelbine With Methotrexate/Fluorouracil Effective In Metastatic Breast Cancer - Doctor's Guide, 4/29/03
• Mammography: Get It or Not? - WebMD, 4/23/03
• Research Uncovering Breast Cancer Risk Factors - Doctor's Guide, 4/15/03
• Accelerated Radiation Treatment For Early Stage Breast Cancer Into Clinical Settings - Doctor's Guide, 4/16/03
• New Directions in Adjuvant Chemotherapy for Breast Cancer - Doctor's Guide, 4/15/03
• Emphasis on Lymph Node Involvement May Fade in Breast Cancer Prognostication and Therapy Selection - Doctor's Guide, 4/15/03
• Granulocyte Colony Stimulating Factor Prevents Febrile Neutropenia in Breast Cancer Patients - Doctor's Guide, 4/14/03
• Underactive Thyroid Lowers Breast Cancer Risk - WebMD, 4/10/03
• Underactive Thyroid Appears To Reduce Breast Cancer Risk - Intelihealth, 4/8/03
• Sonography and Breast Cancer Detection - Physician's Weekly, 4/7/03
• Study: Tamoxifen Could Benefit 2 Million Women - Intelihealth, 4/2/03 - "Tamoxifen is a breast cancer treatment that also can cut by almost half a still-healthy woman's risk of developing the disease. Deciding to use it preventively is a tough choice, however, because tamoxifen can cause uterine cancer and potentially fatal blood clots" - #1 drugstore (no affiliation) usually has good prices on drugs that have gone generic.  Check with your doctor first.
• Genes Determine Breast Cancer, Density - WebMD, 4/1/03
• Pegfilgrastim, Filgrastim Similarly Associated With Bone Pain In Patients With Breast Cancer - Doctor's Guide, 4/1/03
• Epoetin Alfa May Keep Breast Cancer Patients Sharp - Clinical Psychiatry News, 4/03
• Continuous Infusion Of Vinorelbine Means High Efficacy And Toxicity In Heavily Pre-Treated Breast Cancer Patients - Doctor's Guide, 3/31/03
• Key Breast Cancer Decision Measured in Miles - WebMD, 3/28/03
• Breast Cancer Study Highlights Need For Family History Analysis - Doctor's Guide, 3/27/03
• US Lobular Breast Cases Increase Steadily - Doctor's Guide, 3/20/03
• Stn-KLH Vaccine Induces Immune Response In Breast, Ovarian Cancer Following Autologous Stem Cell Transplant - Doctor's Guide, 3/18/03
• Endocrine-Receptor Status Classifications Have High Rate Of Error - Doctor's Guide, 3/18/03
• Do Micromets Make Lymph Nodes Cancer-Positive? - Doctor's Guide, 3/18/03
• Endocrine Therapy - Expert Recommends Starting After Chemotherapy - Doctor's Guide, 3/18/03
• Most Women With Endocrine-Responsive Tumours Should Receive Endocrine Therapy - Doctor's Guide, 3/18/03
• New Guidelines "Liberalize" Use of Breast Cancer Chemotherapy Agents - Doctor's Guide, 3/17/03
• Zoladex (goserelin) Equivalent to Standard Chemotherapy in Estrogen-Receptor-positive, Node-negative, Early Breast Cancer - Doctor's Guide, 3/17/03
• Anti-estrogenic Effects of Hormonal Therapy May Impair Verbal Memory in Breast Cancer Patients - Doctor's Guide, 3/17/03 - "the women from the ATAC trial were significantly impaired on measures of verbal memory and processing speed, as compared with the controls. "And when hormone-replacement therapy in each group was accounted for, the deficits [in the ATAC patients] remained significant," ... animal studies show that estrogen levels affect the structure and function of the hippocampus and frontal lobes of the cortex, which are important for consolidating new memories. And some studies examining the effects of hormone replacement therapy in healthy postmenopausal women show it improves verbal memory and attention"
• Quality of Life Now Looms Larger in Breast Cancer Treatment - Doctor's Guide, 3/17/03
• Vaccine Boosts Immune Response In Breast Cancer Patients Following Autologous Stem Cell Transplant - Doctor's Guide, 3/17/03
• Breast Cancer Spread Foretold? - WebMD, 3/12/03
• Study Finds Breast Cancer Risk Due to Progestins in HRT - WebMD, 3/5/03 - "Women who take combination hormone replacement therapy for more than four years are at very high risk of breast cancer compared with women who have never used HRT. But estrogen-only HRT is virtually free of breast-cancer risk"
• Communication Gaps Mar Breast Cancer - WebMD, 2/26/03
• Marker for Spread of Breast Cancer Found - WebMD, 2/26/03
• Condensed Chemotherapy Schedule Improves Cancer Outcome for Breast Cancer Patients - WebMD, 2/18/03
• Recent Trainees Best At Mammograms - Intelihealth, 2/19/03 - "the most recently trained radiologists did best in a test of cancer-detection accuracy"
• Initial Sentinel Lymph Node Biopsy Should Be Separate From Total Mastectomy And Reconstruction - Doctor's Guide, 2/7/03
• Granulocyte-Colony Stimulating Factor Reduces Myelotoxicity, Does Not Influence Response Rate - Doctor's Guide, 2/6/03
• Serum Carcinoembryonic Antigen, CA 15-3 Linked To Outcome In Advanced Breast Cancer - Doctor's Guide, 2/5/03
• FDA Grants Fast Track Designation For AES-14 For Oral Mucositis Associated With Breast Cancer Chemotherapy - Doctor's Guide, 2/4/03
• Epoetin Alfa Improves Exhaustion and Quality of Life in Anaemic Breast Cancer Patients - Doctor's Guide, 2/2/03
• Birth Size Linked to Early Breast Cancer - WebMD, 1/30/03
• FDA Grants Fast Track Designation for ABI-007 for Metastatic Breast Cancer - Doctor's Guide, 1/17/03
• Diet in Puberty Affects Hormone Levels - WebMD, 1/14/03 - "Small changes in diet during puberty can have a big effect on levels of estrogen and other hormones that have been implicated in boosting breast cancer risk in women, raising hope that girls may be able to eat their way to a lower risk decades later"
• Mammograms Benefit Younger Women - WebMD, 1/3/03
• Antipsychotic Dopamine Antagonists May Increase Breast Cancer Risk - Medscape, 12/27/02
• Subdermal Beats Subareolar Injection For Identification Of Sentinel Lymph Nodes - Doctor's Guide, 12/23/02
• Battling Breast Cancer - CBS News, 12/21/02
• High Response Rate Seen with Neoadjuvant Exemestane in Breast Cancer - Doctor's Guide, 12/17/02
• Cancer Recurrence after Ductal Carcinoma in Situ Carries High Risks - Doctor's Guide, 12/17/02
• Tarceva (Erlotinib, OSI-774) Shows Minimal Activity in Pretreated Women with Breast Cancer - Doctor's Guide, 12/17/02
• Blue Dye And Phytate Radioisotope Combo Is Best For Sentinel Node Biopsy - Doctor's Guide, 12/17/02
• Hormonal Drugs Beat Chemotherapy - WebMD, 12/16/02
• Celecoxib May Improve Breast Cancer Outcomes - Doctor's Guide, 12/16/02
• Estradiol Alone Does Not Increase Breast Cancer Risk - Doctor's Guide, 12/16/02 - "Hormone replacement therapy containing progestins significantly elevates breast cancer risk, but preparations containing estradiol alone do not, a large Swedish observational study suggests"
• Hormone Replacement Linked to Fewer Bone Metastases - Doctor's Guide, 12/16/02
• Zoledronic Acid Significantly Better Than Pamidronate in Patients With Breast Cancer And Bone Metastasis - Doctor's Guide, 12/13/02
• More Than Half Of Breast Cancer Patients Have Osteopenia Or Osteoporosis Regardless Of Hormone Receptor Status - Doctor's Guide, 12/13/02
• Dose-dense Chemotherapy Benefits Breast Cancer Patients - Doctor's Guide, 12/13/02
• Dendritic Vaccine Shows Promise for Metastatic Breast Cancer - Doctor's Guide, 12/13/02
• Biologic Agent [ZD1839 (Iressa)] May Benefit Some Breast Cancer Patients - Doctor's Guide, 12/13/02
• Anthracycline-Based Regimen For Breast Cancer Superior To Cyclophosphamide/Methotrexate/Fluorouracil Combo - Doctor's Guide, 12/13/02
• Survival Similar with Breast Conservation Versus Mastectomy after Nearly 20 Years - Doctor's Guide, 12/13/02
• Frequent Chemo Ups Breast Cancer Survival - WebMD, 12/12/02
• Breast Tumor "Profile" Narrows Treatment - WebMD, 12/12/02
• Radiofrequency Ablation Effective in Small Breast Cancers - Medscape, 12/12/02
• Pathologist Assessment of HER-2/neu Status Concordant with Automatic Image Analysis - Doctor's Guide, 12/12/02
• Chemoendocrine Therapy Effective for Node-Negative, Estrogen-receptor Negative Breast Cancer - Doctor's Guide, 12/12/02
• Zoledronic Acid Reduces Bone Loss - Doctor's Guide, 12/12/02
• Communication Needed Between Relatives About Genetic Testing for Hereditary Breast, Ovarian Cancer - Doctor's Guide, 12/11/02
• Computer-Aided Diagnosis Systems Appear Equally Effective for Breast Cancer - Doctor's Guide, 12/6/02
• Periareolar Injection Successful in Locating Sentinel Nodes in Breast Cancer Patients - Doctor's Guide, 12/3/02
• Breast Cancer Risk Subsides After HRT - WebMD, 12/2/02
• Adding Docetaxel to CVAP as Neoadjuvant Therapy Improves Outcomes for Breast Cancer Patients - Doctor's Guide, 11/29/02
• Hormone Therapy, Alcohol Use Studied - Intelihealth, 11/19/02 - "a postmenopausal woman who has a lifetime breast cancer risk of 4 percent could increase the risk to 8 percent if she drinks and takes hormones"
• Mammograms Benefit Older Women - WebMD, 11/18/02
• New Weapon In Cancer War [Advexin]? - CBS News, 11/16/02
• Granulocyte Colony-Stimulating Factor Beats Leridistim for Preventing Chemotherapy-Induced Febrile Neutropenia - Doctor's Guide, 11/15/02
• Protein [cyclin E] May Predict Spread Of Cancer - Intelihealth, 11/14/02
• Rising breast cancer rate fuels environmental concerns - MSNBC, 10/23/02 - "Breast cancer jumped by 72 percent among Marin [County, Calif.] women ages 46 to 64 during the 1990s ... Common pollutants, such as benzene, a compound found in car exhaust, are linked to breast tumors, and people who move to industrialized counties suddenly face a higher breast cancer risk within one generation ... In the case of breast cancer, new diagnoses have, in fact, been growing at a rate of .6 percent per year nationwide"
• Trastuzumab + Vinorelbine Effective First-Line Therapy in HER2 Over-expressing Metastatic Breast Cancer - Doctor's Guide, 10/23/02
• Goserelin an Effective Alternative to CMF in Oestrogen-receptor Positive Early Breast Cancer - Doctor's Guide, 10/19/02
• Estrogen OK for Some After Breast Cancer - WebMD, 10/18/02
• Mastectomy, Lump Removal Seen Equal - Intelihealth, 10/17/02
• Mastectomy Not Necessary for Early-Stage Breast Cancer - WebMD, 10/16/02
• Brachytherapy Zaps Breast Cancer - WebMD, 10/8/02
• Lumpectomy And Radiation Offers Equivalent Overall And Disease-Free Survival To Mastectomy - Doctor's Guide, 10/7/02
• Increased Breast Cancer Risk Shown Among Women Who Smoked In Adolescence - Doctor's Guide, 10/4/02
• Teen Smokers Risk Breast Cancer - WebMD, 10/3/02
• Alternations in glucose metabolism increase risk for breast cancer in young women - Doctor's Guide, 10/1/02
• Chemotherapy Offers No Survival Advantage Over Endocrine Therapy But Demonstrates Greater Antitumor Activity - Doctor's Guide, 10/1/02
• Significant Impact On Breast Cancer Management From BRCA1 Finds - Doctor's Guide, 9/30/02
• Non-steroidal Anti-inflammatory Drug Use May Slow Breast Cancer Tumour Growth, Prevent Distant Metastasis - Doctor's Guide, 9/30/02 - "increasing NSAID use may retard the growth of breast tumours and may prevent distant metastasis"
• Pregnancy hormone estriol may reduce risk for breast cancer - Doctor's Guide, 9/30/02
• Seniors With Breast Cancer Also Benefit From Aggressive Treatment - Doctor's Guide, 9/27/02
• Hormone Replacement Therapy Has Only Positive Effects On Detection Of Breast Cancer - Doctor's Guide, 9/25/02
• Brachytherapy Boost to Stage I-II Breast Tumour Beds Indicated as Treatment of Choice - Doctor's Guide, 9/20/02
• Breast Density Affects Cancer Screening - WebMD, 9/19/02
• Reusable Compensator Library Reduces Dose Inhomogeneity in Breast Tangential Radiotherapy - Doctor's Guide, 9/18/02
• Mammogram Results May Depend on Doctor - WebMD, 9/17/02
• Hormone Replacement Therapy may Improve Breast Cancer Detection and Survival Rate - Doctor's Guide, 9/13/02
• Good (Breast Cancer) News for HRT Users - WebMD, 9/12/02
• Estrogen Therapy Appears Safe For Women With Early Breast Cancer - Doctor's Guide, 9/10/02 - "Estrogen replacement therapy does not appear to increase risk of recurrence or death in women with early breast cancer"
• Large-Core Needle Biopsy Effective in Benign Breast Lesions - Doctor's Guide, 8/30/02
• Chronic Marimastat Therapy Invalid in Adjuvant Treatment of Breast Cancer - Doctor's Guide, 8/28/02
• Trial of Sequential Docetaxel, Doxorubicin/Cyclophosphamide Ends - Doctor's Guide, 8/27/02
• Introduction of Mammography Reduces Mastectomy Rates - Doctor's Guide, 8/22/02
• No Advantage in Radical Over Total Mastectomy: 25-year Study - Doctor's Guide, 8/22/02
• Childhood Growth Linked to Breast Cancer - WebMD, 8/19/02
• Urokinase-type Plasminogen Activator Inhibitors, but Not the Activator Itself, Predict Outcome in Breast Cancer Patients - Doctor's Guide, 8/15/02
• Gemcitabine Plus Trastuzumab Improves Outcomes in Previously Treated, Metastatic Breast Cancer Patients - Doctor's Guide, 8/13/02
• Intradermal Beats Intraparenchymal Injection for Detecting Sentinel Nodes in Breast Cancer - Doctor's Guide, 8/12/02
• Doxorubicin/cyclophosphamide Reduces Recurrence in Node Negative, Rapidly Proliferating Breast Cancer - Doctor's Guide, 8/12/02
• Federal Study Shows No Link Between Pollution And Breast Cancer - Intelihealth, 8/6/02
• Study backs use of mammograms - USA Today, 8/1/02 - "Among screened women between 40 and 69, the breast cancer death rate dropped 44% after mammography became routine ... But breast cancer activist Barbara Brenner, executive director of Breast Cancer Action in San Francisco, calls the benefit of early detection "a myth.""
• Younger Premenopausal Women with Breast Cancer Have Poorer Prognosis than Older Women - Doctor's Guide, 7/23/02
• Breast-Conserving Therapy Provides Outcomes Comparable to Modified Radical Mastectomy - Doctor's Guide, 7/18/02
• Breast Cancer Mortality Higher In Early Radiation Technicians - Doctor's Guide, 6/20/02
• Breast Cancer Rising Among Asian-American Women - Doctor's Guide, 6/10/02 - "The Japanese lifestyle has become increasingly Westernized, study authors note, influencing factors known to increase risk for breast cancer: having fewer children, engaging in less physical activity and experiencing increasing obesity. Japanese are also eating more fats and fewer soy products"
• Breast Feeding Can Reduce Childhood Obesity - Doctor's Guide, 6/6/02
• Cancer in Context: What Are Your Odds? - WebMD, 6/4/02
• Communication Key To Breast Cancer Care In Older Women - Doctor's Guide, 6/4/02
• Test Predicts If Breast Cancer Chemotherapy Will Work - Doctor's Guide, 6/3/02
• Goserelin Protects Ovarian Function In Pre-Menopausal, Early-Stage Breast Cancer - Doctor's Guide, 5/29/02
• Minimally Invasive Diagnostic Technique Useful For All Non-Palpable Breast Lesions - Doctor's Guide, 5/23/02
• Risk Of Subsequent Sarcoma Small In Breast Cancer Radiotherapy - Doctor's Guide, 5/22/02
• Oophorectomy Curbs Ovarian And Breast Cancer Risks In Carriers of BRCA Mutations - Doctor's Guide, 5/22/02
• Risk Reducing Salpingo-Oopherectomy Significantly Reduces Risk of Breast Cancer and BRCA-Related Gynecologic Cancer - Doctor's Guide, 5/21/02
• Ovary Removal Prevents Breast Cancer - WebMD, 5/20/02
• Disease-Free Survival Benefit Seen by Switching from 5-Flourouracil-based to Docetaxel-based Breast Cancer Therapy - Doctor's Guide, 5/20/02
• Breast Cancer Therapy Heats Up - WebMD, 5/18/02
• Moderate Drinking Increases Insulin Sensitivity In Non-Diabetic, Older Women - Doctor's Guide, 5/16/02 - "Researchers warn, however, that the alcohol intake significantly increased serum levels of dehydroepiandrosterone sulphate and estrone sulphate, steroid hormones known to be risk factors for breast cancer"
• Doxorubicin-Based Adjuvant Therapy Beneficial In Stage II Breast Cancer - Doctor's Guide, 5/8/02
• Triple Risk For Breast Cancer Twins - Doctor's Guide, 5/6/02
• Ductography May Help Detect Breast Malignancy - Doctor's Guide, 5/2/02
• Menstrual Cycle Phase Important In Mastectomy Plus Oophorectomy - Doctor's Guide, 5/2/02
• Breast Cancer Detection Rates Go Up, Patient Recall Rates Go Down With Consensus Double Reading - Doctor's Guide, 4/29/02
• High Levels of Sex Hormones Raise Breast Cancer Risk in Older Women - Doctor's Guide, 4/17/02 - "Postmenopausal women with high amounts of oestrogen and testosterone in their bloodstream are at over twice the risk of the disease as those with low levels of the hormones ... obesity is the biggest known reason for high levels of sex hormones among postmenopausal women ... women with raised levels of a molecule called sex hormone binding globulin, which reduces the activity of sex hormones, were at lower than usual risk. Interestingly, women who are obese have low levels of this molecule, which probably also helps to raise their risk of breast cancer"
• Contralateral Prophylactic Mastectomy Reduces Risk for Second Primary Cancer in Women with Stage 1 or 2 Primary Breast Cancer and Positive Family History - Doctor's Guide, 4/15/02
• Extra Pounds Raise Breast Cancer Risk - WebMD, 4/10/02
• Adjuvant Radiotherapy Increases Risk of Second Primary Cancer in Contralateral Breast - Doctor's Guide, 4/8/02
• Two Mapping Techniques Needed to Detect Sentinel Lymph Nodes in Breast Cancer - Doctor's Guide, 4/1/02
• Breast Cancer Vaccine Now in Early Trial - WebMD, 3/25/02
• Oral Contraceptives may Increase Risk of Breast Cancer - Doctor's Guide, 3/25/02
• Axillary Dissection Can Be Safely Avoided When Breast Cancers Are Small - Doctor's Guide, 3/25/02
• The Pill May Increase Breast Cancer - WebMD, 3/23/02
• Biopsies of Internal Mammary Sentinel Nodes may Improve Patient Survival in Breast Cancer - Doctor's Guide, 3/22/02
• Breast Cancer Choices Denied, Some Surgeons Don't Tell Women About Surgery Options - WebMD, 3/22/02
• Hormone Therapy May Provide Greater Gains Than Chemotherapy In Breast Cancer Treatments - Doctor's Guide, 3/20/02
• Surgeons Don't Offer Breast Cancer Patients Choices Of Treatment As Often As They Could - Doctor's Guide, 3/20/02
• Major Study Reaffirms That Regular Mammograms Save Life - Intelihealth, 3/14/02
• Better Breast Cancer Test - WebMD, 3/11/02
• Positron Emission Tomography Proves Best for Finding Recurrent Breast Cancer - Doctor's Guide, 3/7/02
• Endoscopic-Assistance With Mastectomy Improves Cosmetic Results, Patient Satisfaction - Doctor's Guide, 3/4/02
• Aromatase Inhibitors Added to Guidelines for Breast Cancer Treatment - Doctor's Guide, 3/4/02
• Microwave Therapy Improves Chance Of Saving Breast - Doctor's Guide, 3/3/02
• Exposure To Electromagnetic Fields, Light At Night May Be Risk Factor For Male Breast Carcinoma - Doctor's Guide, 3/1/02
• Study Confirms HRT Ups Breast Cancer Risk - WebMD, 2/12/02 - "The risk of ductal cancer -- the most common form of breast cancer -- increases by 50% in women who have used HRT for five recent years ...If our results are correct, then nonusers of HRT would have an incidence of ductal cancer of about 230 per 100,000 women per year, whereas women with five years of recent HRT use would have a rate of 349 per 100,000 women per year"
• Radiofrequency Energy Zaps Breast Cancer Tumors - WebMD, 2/7/02
• Sentinel Lymph Node Biopsy In Breast Cancer Cannot Be Ignored - Doctor's Guide, 2/5/02
• Researcher: Mammography Saves Lives - Intelihealth, 2/1/02
• Omitting Axillary Dissection for Invasive Breast Carcinoma May Be Ill-advised - Doctor's Guide, 1/29/02
• Many Women With Newly Diagnosed Breast Carcinoma Likely To Harbour BRCA1/2 Mutation - Doctor's Guide, 1/29/02
• Should I Get a Mammogram This Year? - WebMD, 1/29/02
• Cancer Combo [Herceptin & Iressa] Delivers One-Two Punch - WebMD, 1/28/02
• Mammogram Advice In Dispute - Intelihealth, 1/25/02
• Two Biomarkers Help Predict Course of Breast Cancer - Doctor's Guide, 1/21/02
• New Guidelines Released on Ductal Lavage for Managing High Risk Breast Cancer - Doctor's Guide, 1/14/02
• Estradiol Levels Could Determine Breast Cancer Risk in Older Women - Doctor's Guide, 1/10/02
• Estrogen Level Determines Osteoporosis Drug's Breast Cancer Prevention Effectiveness in Postmenopausal Women - Doctor's Guide, 1/9/02
• Autologous Reinfusions Induce Rapid T-Cell Recovery After High Dose Chemotherapy For Metastatic Breast Cancer - Doctor's Guide, 1/9/02
• Study Reveals Healthy Outlook For Long-Term Breast Cancer Survivors - Doctor's Guide, 1/2/02
• Tall Thin Girls May Have Increased Breast Cancer Risk - Doctor's Guide, 12/24/01
• Breast Cancer Surgery Without the Knife - WebMD, 12/19/01
• Combination of Taxane and Anthracycline Results in Complete Responses Among Women with Inflammatory Breast Cancer - Doctor's Guide, 12/14/01
• Navelbine (Vinorelbine Tartate) Promising In Treatment For Metastatic Breast Cancer - Doctor's Guide, 12/13/01
• Mastectomy Offers Best Prognosis After Local Breast-Cancer Recurrence - Doctor's Guide, 12/13/01
• Inhibition of VEGF by Experimental Drug TSU-68 Appears to Synergistically Improve Anti-tumor Action - Doctor's Guide, 12/13/01
• Caelyx (Doxorubicin Liposome Injection) Well Tolerated by Patients with Advanced Breast Cancer - Doctor's Guide, 12/13/01
• Axillary Dissection, Radiation Offer Equal Survival in Early Breast Cancer - Doctor's Guide, 12/13/01
• High-Dose Epirubicin Plus Docetaxel Appears Effective in Locally Advanced Breast Cancer Without Cardiac Toxicity - Doctor's Guide, 12/12/01
• Study Raises Mammogram Questions - Intelihealth, 12/11/01
• Breast Fluid May Mean Cancer Risk - Intelihealth, 12/5/01
• Laser-Induced Thermotherapy Destroys Cancer Metastases, Relieves Pain - Doctor's Guide, 11/29/01
• Lavage Treatment Detects High Risk For Breast Cancer - Intelihealth, 11/20/01
• Anxiety Prevents Women From Performing Breast Self-Exams - WebMD, 11/8/01
• Booster Radiation Cuts Chance of Breast Cancer Coming Back - WebMD, 11/7/01
• Study Finds Double Mastectomy Reduces Breast Cancer Rate To Near Zero For Very High Risk Women - Intelihealth, 11/7/01
• New Procedure Detects Early Breast Cancer Cells - WebMD, 11/6/01
• Dispelling the Myths Behind Breast Cancer and Family - WebMD, 10/25/01
• Technique May Save Lymph Nodes - Intelihealth, 10/23/01
• Radioactive Tracer Approach Reduces Surgical Trauma in Breast Cancer - Doctor's Guide, 10/22/01
• Zometa (Zoledronic Acid for Injection) Reduces Bone Complications in Multiple Myeloma/Breast Cancer - Doctor's Guide, 10/22/01
• How Likely Are You to Get Breast Cancer? - WebMD, 10/18/01
• Doctor Offers Closest Recommendation Yet for Estrogen Use in Breast Cancer Survivors - Doctor's Guide, 10/8/01
• Venlafaxine Reduces Menopausal Symptoms in Breast Cancer Survivors Who Cannot Take Estrogen - Doctor's Guide, 10/8/01
• Breast Cancer Survivors Finally Have Weapon Against Menopause, Antidepressants Relieve Hot Flashes - WebMD, 10/4/01 - "breast cancer survivors treated with the antidepressant Effexor had a 60% reduction in hot flashes. The widely prescribed antidepressants Prozac and Paxil also appear to be effective"
• Emotional Turmoil of Breast Cancer Therapy Eases Soon After - WebMD, 9/12/01
• Positron Emission Tomography Scan Results in Management Changes for Majority of Breast Cancer Patients - Doctor's Guide, 9/4/01
• Weekly Docetaxel Shows Promise In Older Patients With Advanced Breast Cancer - Doctor's Guide, 8/1/01
• Women With Family History of Breast Cancer Could Benefit From MRI Screening - WebMD, 7/26/01
• Removing Healthy Breasts From High-Risk Women - WebMD, 7/18/01
• Bone Marrow Transplant Still an Option for Breast Cancer - WebMD, 7/6/01
• Second Breast Cancers May Be Harder to Treat in Women Taking Tamoxifen - Doctor's Guide, 7/4/01
• Drug's Affect On Breast Cancer Studied - Intelihealth, 7/3/01
• Breast Cancer Risk Lower for Older Women With Weak Bones - WebMD, 6/19/01
• Weekly Paclitaxel Better Than Standard Dosage For Breast Cancer Treatment - Doctor's Guide, 5/15/01
• Anti-Aromatase Agents Cost-Effective For Women With Metastatic Breast Cancer - Doctor's Guide, 5/15/01
• Hormone Therapy -- Is It Safe for Breast Cancer Survivors? - WebMD, 5/15/01
• Hormones may cut risk for breast cancer patients - USA Today, 5/15/01 - "Hormone replacement therapy after a diagnosis of breast cancer does not increase the risk of recurrence of the disease and may even lower chances that the cancer will return"
• Aromasin (Exemestane Tablets) Demonstrates High Response Rate Versus Tamoxifen In First-Line Treatment of Advanced Breast Cancer - Doctor's Guide, 5/14/01
• Femara (Letrozole Tablets) Demonstrates Superiority Over Tamoxifen in Advanced Breast Cancer - Doctor's Guide, 5/14/01
• Weekly Paclitaxel Well Tolerated By Elderly Women With Metastatic Breast Cancer - Doctor's Guide, 5/14/01
• Aromatase Inhibition Does Not Interfere With Serum Lipids In Metastatic Breast Cancer - Doctor's Guide, 5/14/01
• Taxotere, Carboplatin And Herceptin Combination Effective, Safe In Metastatic Breast Cancer - Doctor's Guide, 5/14/01
• Paclitaxel Reverses Unfavorable Prognosis In HER2/Neu Metastatic Breast Cancer - Doctor's Guide, 5/14/01
• Arimidex Reinforced As A First-Line Choice For Patients With Aggressive Metastatic Breast Cancer - Doctor's Guide, 5/12/01
• Giving Tamoxifen Therapy for More Than Five Years Is Unnecessary, Study Finds - WebMD, 5/1/01
• New Milk Duct Test May Detect Breast Cancer Earlier, But May Be Appropriate Only for High-Risk Women - WebMD, 4/26/01
• Radioactive 'Seeds' as Effective as Beams for Breast Cancer - WebMD, 4/12/01
• Very Low Dose Zoledronic Reduces Bone Metastases In Metastatic Breast Cancer And Multiple Myeloma - Doctor's Guide, 4/2/01
• Breast Cancer Drug Does Not Cause Sexual and Mood Effects - WebMD, 3/29/01 - "While the study found no side effects related to sexuality or mood, it did find that women taking tamoxifen had more menopauselike symptoms"
• Another Link Between Cox-2 Expression and Breast Cancer - Doctor's Guide, 3/29/01 - "This finding leaves the door open to studies that would determine whether treatment with COX-2 inhibitors might somehow affect tumor progression"
• Light May Help Find Breast Cancer - Intelihealth, 3/19/01
• Study Raises Safety Issues With Cancer Drug - Intelihealth, 3/16/01 - "Herceptin and doxyrubicin together seemed to affect the hearts of test patients, causing fatigue, shortness of breath and other symptoms ... these side effects do not occur when Herceptin is given with two other chemotherapy agents, taxotere and carboplatin ... early administration of Herceptin might breed tumors resistant to the drug, rendering it useless when current treatments fail and Herceptin is needed for late-stage cancers"
• Good News for Breast Cancer Survivors - WebMD, 3/16/01 - "They actually may have less risk of developing colon or rectal cancer than women who have not had breast cancer"
• Herceptin Offers Hope for Some Women With Advanced Breast Cancer, Biotech Drug Shrinks Aggressive Tumors, Improves Chemotherapy - WebMD, 3/14/01 - "Herceptin, a bioengineered antibody developed by Genentech Inc., clicks onto the HER2 molecules that studded the surface of Empey's stubborn breast cancer cells. This blocks HER2 from sending the signals that help cancer cells grow and spread. The result is often that the tumors shrink and wither away."
• Herceptin With Chemotherapy Increases Median Survival In Metastatic Breast Cancer - Doctor's Guide, 3/14/01
• Mammography: 'Gold Standard' Could Use Some Polish - WebMD, 3/12/01
• Digital Mammograms Won't Make Screening More Comfortable - WebMD, 3/9/01 - "Having a good, skilled, competent radiologist is more important than which technology is used"
• Standard mammogram still best at detecting cancer - USA Today, 3/8/01
• Do Abortions Increase Breast Cancer Risk? - WebMD, 3/7/01 - "We really think there is no association between breast cancer and abortion."
• Old-Fashioned Mammograms Best To Detect Breast Cancer - Intelihealth, 3/8/01
• Friends may make breast cancer more survivable - USA Today, 3/7/01
• Scientists learning how breast cancer spreads - USA Today, 2/28/01
• The End of the Road for Mammograms? New Handheld Devices More Comfortable, and Perhaps More Accurate - WebMD, 2/28/01
• Scientists Gain Breast Cancer Facts - Intelihealth, 2/28/01
• Surviving Breast Cancer After Menopause, Age and Other Illnesses Influence Your Chances of Survival - WebMD, 2/20/01
• Prognosis Not So Bright For New Breast Disease Drug (Iogen for fibrocystic breast disease) - Intelihealth, 2/16/01 - "iodine rids women suffering from FBD of symptoms. Two unrelated studies, one in Canada and one in Russia, involving nearly 1,500 women, showed iodine reduced the number of cysts and the level of pain. . . . Iogen contains no iodine, but when it is broken down by the body, it becomes molecular iodine. And unlike the iodine found in foods, which is toxic to the thyroid in large quantities, Iogen seems to deliver large doses of pure iodine without dangerous side effects."
• New treatments hold out hope for breast cancer patients - CNN, 1/26/01
• Chemo Urged For Small Breast Tumors - Intelihealth, 1/16/01
• Radioactive Seeds May Offer Treatment Option for Breast Cancer - WebMD, 1/16/01
• FDA Approves Breast Cancer Drug - Intelihealth, 1/11/01
• New First-Line Drug Approved for Advanced Breast Cancer, Femara May Be Better Than Present Drug of Choice - WebMD, 1/10/01
• Heading Breast Cancer Off at the Pass, The Experts Debate Prevention Through Surgery - WebMD, 12/20/00
• Anti-depressant (Effexor®/venlafaxine) counters hot flashes from menopause, chemotherapy - CNN, 12/15/00 - ""I think it represents the best of the non-hormonal options for treating hot flashes in women with breast cancer.""
• Breast Cancer Drug Takes Big Step Toward First Place, FDA Advisers Back Femara as Drug Treatment of Choice - WebMD, 12/13/00
• FDA Committee Recommends Femara (Letrozole) For Advanced Breast Cancer - Doctor's Guide, 12/13/00
• Dolastatin-10 Does Not Improve Advanced Breast Cancer - Doctor's Guide, 12/11/00
• Better Survival With Arimidex (Anastrozole) Than Tamoxifen In Postmenopausal Women With Advanced Breast Cancer - Doctor's Guide, 12/11/00
• One Or Two Sentinel Node Biopsies Predict Early Stage Breast Cancer - Doctor's Guide, 12/11/00
• First-Line Anastrozole Effective Against Advanced Breast Cancer After Tamoxifen - Doctor's Guide, 12/8/00
• Doxorubicin/Docetaxel Effective For Breast Cancer  - Doctor's Guide, 12/8/00
• Faslodext (ICI182,780) At Least As Effective As Arimidex (Anastrozole) In Advanced Breast Cancer - Doctor's Guide, 12/7/00
• Femara (Letrozole) Significantly More Effective Than Tamoxifen In Treating Advanced Breast Cancer - Doctor's Guide, 12/7/00
• Aromasin (Exemastane) May Be More Effective Than Tamoxifen In Postmeopausal Breast Cancer - Doctor's Guide, 12/7/00
• New Therapy Helpful in Advanced Breast Cancer, Faslodex Safe, Effective in Estrogen-Sensitive Tumors - WebMD, 12/6/00
• Hormone Replacement Therapy and Breast MRI Don't Mix - WebMD, 12/5/00
• Breast Cancer "Cure" Without Surgery - Doctor's Guide, 11/28/00
• New Answer for Tamoxifen Problem, Birth Control Device May Prevent Unwanted Side Effects - WebMD, 11/16/00
• Femara (Letrozole) More Effective Than Tamoxifen As First-Line Treatment For Advanced Breast Cancer - Doctor's Guide, 11/9/00
• Promising New Therapy for Advanced Breast Cancer - WebMD, 11/9/00
• Experts Reach a Consensus for Breast Cancer Treatment - WebMD, 11/3/00
• Breast Cancer: Is the Race for a Cure Nearing the Finish Line? - WebMD, 10/30/00
• The Skinny On High-Fat Diets and Breast Cancer - WebMD, 10/27/00
• Radiotherapy And Chemotherapy Should Be Concurrent For Early Breast-cancer - Doctor's Guide, 10/27/00
• Battling breast cancer -- a reporter's perspective - CNN, 10/26/00
• Half-body Irradiation Provides Rapid Palliation In Metastatic Breast Cancer - Doctor's Guide, 10/25/00
• Aromasin (Exemestane) Promising In Adjuvant Treatment For Breast Cancer - Doctor's Guide, 10/13/00
• The Pill and Breast Cancer Risk: More Food for Thought - WebMD, 10/10/00
• Breast Reconstruction During Mastectomy Boosts Well-Being - Doctor's Guide, 10/2/00
• Women With Hereditary Breast Cancer Can Safely Have Radiation - WebMD, 9/29/00
• American Women Often Missing out on Best Breast Cancer Care - WebMD, 9/28/00
• Zoladex (Goserelin) As Effective As Standard Chemotherapy In Early Breast Cancer - Doctor's Guide, 9/27/00
• Radiotherapy Booster Cuts Risk Of Breast Cancer Recurrence - Doctor's Guide, 9/19/00
• Breast-Reduction Surgery May Reduce Breast Cancer Risk - WebMD, 9/19/00
• What Lies in the Wake of Various Breast Cancer Surgeries? - WebMD, 9/6/00
• Study Shows Breast Cancer Risk Starts Early -- Really Early - WebMD, 8/31/00
• A New Way to Tell Who's at High Risk for Breast Cancer - WebMD, 8/3/00
• More Older Women Getting Breast-Conserving Surgery - WebMD, 8/3/00
• Watching Your Waist May Reduce Breast Cancer Risk - WebMD, 7/24/00
• New Laser Treatment May Replace Lumpectomy In Breast Cancer - Doctor's Guide, 7/18/00
• No Need for Extra Tests to Detect Breast Cancer's Return - WebMD, 7/11/00
• Do Antidepressants Increase Breast Cancer Risk? - WebMD, 6/16/00
• Researchers Say Herbal Formula Offers Relief From Chemotherapy Ills - Intelihealth, 6/16/00
• Having Babies Before Age 30 Cuts Risk of Breast Cancer - WebMD, 6/15/00
• Hormones Said Raising Breast Cancers - Intelihealth, 6/1/00
• Zoladex (Goserelin) May Be Effective in Pre-Menopausal Breast Cancer - Doctor's Guide, 5/24/00
• Herceptin (Trastuzumab) Prompts Promising Response In Advanced Breast Cancer - Doctor's Guide, 5/23/00
• Fareston (Toremifene Citrate) as Effective as Tamoxifen in Breast Cancer - Doctor's Guide, 5/23/00
• Shorter Treatments Available for Breast Cancer Patients - WebMD, 5/22/00
• Newer Depression Drug (Effexor) Relieves Hot Flashes - WebMD, 5/22/00
• Paroxetine Effective Against Hot Flushes in Survivors of Breast Cancer - Doctor's Guide, 5/19/00
• Radiation Cuts Risk of Breast Cancer Recurrence by Two-Thirds - WebMD, 5/18/00
• Drug May Ease Hot Flashes In Women With Breast Cancer - Intelihealth, 5/16/00
• Are Breast Cancers Detected by Mammography Different? - WebMD, 4/24/00
• Older Breast Cancer Patients Live As Long As Non-Patients - Intelihealth, 4/5/00
• Test May Rule Out Chemotherapy Need - Intelihealth, 4/4/00
• New Test Predicts Node-negative Breast Cancer Metastases - Doctor's Guide, 4/4/00
• Mastectomy Protects Against Breast Cancer in Women with Genetic Mutations - Doctor's Guide, 4/3/00
• Breast Cancer Support Groups Not Right For All Women - Intelihealth, 3/29/00
• Study Questions Breast Cancer Treatment - Intelihealth, 3/6/00
• Breast Cancer Experts Agree On Treatment Options For Early Breast Cancer - Doctor's Guide, 2/15/00
• Paclitaxel/Carboplatin Combination Achieves Encouraging Results In Breast Cancer - Doctor's Guide, 2/15/00
• Calcium Deposits May Be Key To Breast Cancer Survival - Intelihealth, 2/7/00
• Taxotere And Adriamycin Combo Effective For Breast Cancer - Doctor's Guide, 2/3/00
• Anastrozole May Replace Tamoxifen In Postmenopausal Breast Cancer - Doctor's Guide, 2/1/00
• Weekly Docetaxel Plus Doxorubicin Effective In Advanced Breast Cancer - Doctor's Guide, 1/31/00
• Estrogen/Progestin HRT Seems To Increase Risk Of Breast Cancer - Doctor's Guide, 1/25/00
• Aromasin Now Available In US For Advanced Breast Cancer - Doctor's Guide, 1/24/00
• BREAST CANCER: Prozac Treats Hot Flashes - Doctor's Guide, 12/15/99
• BREAST CANCER: Radiation After Conservative Surgery Reduces Recurrences - Doctor's Guide, 12/15/99
• Outlook Good For Women With Early Breast Cancer - Doctor's Guide, 12/15/99
• Estrogen Replacement Therapy Studied In Breast-Cancer Survivors - Doctor's Guide, 12/14/99
• Herceptin, In Adjunct Therapy, Reducing Tumor Size - Doctor's Guide, 12/13/99
• Bisphosphonates May Reduce Metastases - Doctor's Guide, 12/13/99
• Navelbine Plus Herceptin Promising For Metastatic Breast Cancer - Doctor's Guide, 12/10/99
• Neoadjuvant Therapy With Taxotere Improves Efficacy - Doctor's Guide, 12/10/99
• Zoladex May Further Reduce Breast Cancer Recurrence In Premenopausal Women - Doctor's Guide, 12/10/99
• Arimidex More Effective Than Nolvadex For Advanced Breast Cancer - Doctor's Guide, 12/10/99
• Chemo May Not Be Necessary In Treatment Of Small Breast Tumors - Doctor's Guide, 12/10/99
• Chemotherapy More Effective When Combined With Taxotere - Doctor's Guide, 12/10/99
• Breast-Cancer Surgery Chances Are Improved By Timing - Intelihealth, 11/15/99
• Nontoxic Drug Shown To Help Reduce Return Of Breast Cancer - Intelihealth, 11/3/99
• Lumpectomy Offers Same Survival To Mastectomy In Breast Cancer Relapse - Doctor's Guide, 11/2/99
• Research Identifies Factors Leading To Better Breast Cancer Treatment - Doctor's Guide, 9/30/99
• Inherited Breast Cancer Gene Liked To Recurrence, New Tumors - Doctor's Guide, 9/29/99
• Researchers Baffled By Low Use Of Axillary Node Dissection In Breast Cancer - Doctor's Guide, 9/23/99
• Taxol®/Doxorubicin Improves Survival In Metastatic Breast Cancer - Doctor's Guide, 9/24/99
• Axillary Node Dissection Improves Outcome In Breast Cancer Patients - Doctor's Guide, 9/21/99
• FDA Advisory Panel Backs Taxol For Adjuvant Breast Cancer Treatment - Doctor's Guide, 9/17/99
• Anastrazole Shows Equal Efficacy To Tamoxifen In Advanced Breast Cancer - Doctor's Guide, 9/16/99
• New Drug Combination Enhances Treatment For Advanced Breast Cancer - Doctor's Guide, 9/16/99
• Anastrozole As Effective As Tamoxifen For Advanced Breast Cancer In Postmenopausal Women - Doctor's Guide, 9/15/99
• Ovary Removal Reduces Risk Of Breast Cancer In Women With BRCA1 Mutation - Doctor's Guide, 8/31/99
• Behavioral Program Boosts Antibody That Fights Breast Cancer - Doctor's Guide, 8/24/99
• Study Shows Taxol Improves Survival In Metastatic Breast Cancer Patients - Doctor's Guide, 8/4/99
• Researchers Seek Link Between Breast Cancer And Artificial Light - Intelihealth, 8/2/99
• PCBs Linked To Breast Cancer Risk, Study Shows - Doctor's Guide, 7/29/99
• Anthracycline Superior To Cyclophosphamide/Methotextrate/5FU - Doctor's Guide, 7/28/99
• Taxol, Taxotere Equally Effective In Metastatic Breast Cancer - Doctor's Guide, 7/28/99
• Depression In Breast Cancer Patients Linked To Lack Of Estrogen - Doctor's Guide, 6/29/99
• First Clinical Guidelines For Breast Cancer Risk Reduction Published - Doctor's Guide, 6/11/99
• Breast cancer detection: Upping your odds for survival - CNN, 5/25/99
• New Mastectomy Operation Rebuilds Lost Breasts - Intelihealth, 5/24/99
• Taxotere Plus Adriamycin Outperforms Standard Combination In Breast Cancer - Doctor's Guide, 5/17/99
• Thorough breast cancer surgery may make radiation unnecessary - CNN, 5/14/99
• MRI Most Accurate For Detecting Difficult To Diagnose Breast Cancer - Doctor's Guide, 5/10/99
• HRT Should Be Considered When Determining Breast Cancer Treatment - Doctor's Guide, 5/5/99
• Study endorses quick, easy breast biopsy - CNN, 5/4/99
• Study Finds Lymph Node Surgery Unnecessary For Many Breast Cancer Patients - Doctor's Guide, 4/30/99
• Taxol Improves Breast Cancer Survival When Added To Chemotherapy - Doctor's Guide, 4/29/99
• Side Effects Limiting Chemotherapy - Intelihealth, 4/28/99
• Studies show riskier breast cancer treatment no better than standard chemo - CNN, 4/15/99
• Study Shows Hormone Replacement Therapy Does Not Elevate Breast Cancer Risk - Doctor's Guide, 3/15/99
• Higher Fat Diet Not Linked To Higher Breast Cancer Risk - Doctor's Guide, 3/9/99
• Breast cancer vaccine trials show promise - CNN, 1/14/99
• Evista Reduces Breast Cancer Incidence In Postmenopausal Women - Doctor's Guide, 12/11/98
• New evidence links breast cancer to electromagnetic fields - CNN, 3/24/98
• Femara Effective In Postmenopausal Women With Advanced Breast Cancer - Doctor's Guide, 2/5/98
• New Advanced Breast Cancer Drug Now Available - Doctor's Guide, 10/1/97

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