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Senior Health Concerns

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• Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study - Nutrients 2022 Feb 11 - "Deteriorating sleep quality and physical or mental fatigue in older adults leads to decreased quality of life and increased mortality rates. This study investigated the effects of the time-dependent intake of nicotinamide mononucleotide (NMN) on sleep quality, fatigue, and physical performance in older adults ... NMN (250 mg) or placebo was administered once a day for 12 weeks. Sleep quality was evaluated using the Pittsburgh Sleep Quality Index. Fatigue was evaluated using the "Jikaku-sho shirabe" questionnaire. Grip strength, 5-times sit-to-stand (5-STS), timed up and go, and 5-m habitual walk were evaluated to assess the physical performance. Significant interactions were observed between 5-STS and drowsiness. 5-STS of all groups on post-intervention and drowsiness of the NMN_PM and Placebo_PM groups on mid- and post-intervention showed significant improvement compared with those in pre-intervention. The NMN_PM group demonstrated the largest effect size for 5-STS (d = 0.72) and drowsiness (d = 0.64). Overall, NMN intake in the afternoon effectively improved lower limb function and reduced drowsiness in older adults. These findings suggest the potential of NMN in preventing loss of physical performance and improving fatigue in older adults" - See NMN at Amazon.com.
  • NMN vs NR – 1 Huge Difference | Dr David Sinclair & Dr Andrew Huberman Interview Clips - YouTube - Dr. Sinclair, who had done significant research on NMN, claims MNM is better than the much more expensive NR. Dr. Sinclair makes sense. He confirms a lot of what I've read yet look how few views he gets compared to bullshit artists like Dr. Eric Berg or Dr. John Campbell. For some reason, whether it's politics or health, people prefer lies.
• Vitamin D supplementation reduces the risk of fall in the vitamin D deficient elderly: An updated meta-analysis - Clin Nutr 2021 Sep 27 - "The combination of vitamin D and calcium have beneficial effects on prevention falls in old adults. Although vitamin D supplementation alone has no effect on fall risk in old adults with 25(OH)D levels higher than 50 nmol/L, vitamin D supplementation alone does have a benefit on prevention of falls in old adults with 25(OH)D levels lower than 50 nmol/L" - See vitamin D at Amazon.com and vitamin D at iHerb.
• Very Long-Term Treatment With a Lactobacillus Probiotic Preparation, Lactobacillus casei Strain Shirota, Suppresses Weight Loss in the Elderly - Nutrients 2020 May 29 - "To reveal the potential benefit of long-term lactic acid, the effects of bacteria-based probiotics for health maintenance were examined. This observational study included the participants from a previous clinical study designed to evaluate the effects of wheat bran biscuits or Lactobacillus preparation, 3 g/day biolactis powder (BLP), in preventing colorectal tumor. The participants were provided an option to continue treatment with BLP on an outpatient basis after completion of the study. The 380 patients who completed the study were contacted and asked to participate in the present study and those who consented were surveyed for cancer incidence, treatment compliance, lifestyle, weight, and other variables ... The mean follow-up period was 7913 days (21.7 years). Cancer developed in 24 of 128 (18.8%) patients in the BLP extension group and 24 of 109 (22.0%) patients in the non-BLP extension group (risk ratio 0.88 [95% confidence interval 0.53-1.47]). Although no significant difference was observed, the cumulative cancer incidence rose at a slightly lower rate in the BLP extension group. Both groups showed a significant weight decrease over the course of 20 years, although the decrease in the BLP extension group was only 1.4 kg, compared with 2.8 kg in the non-BLP extension group. Very long-term treatment with a Lactobacillus probiotic preparation suppressed weight loss in the elderly." - See probiotic supplements at Amazon.com and iHerb.
• The Relationship between Nutritional Status, Anemia and Other Vitamin Deficiencies in the Elderly Receiving Home Care - J Nutr Health Aging. 2019;23(7):677-682 - "With or without malnutrition, iron deficiency anemia, vitamin B12 deficiency and vitamin D deficiency were common in the home care elderly patients" - See  iron supplements at Amazon.com, vitamin B12 at Amazon.com and vitamin D at Amazon.com.
• Macronutrients Intake and Incident Frailty in Older Adults: A Prospective Cohort Study - J Gerontol A Biol Sci Med Sci. 2016 Mar 4 - "monounsaturated fatty acids (MUFAs) ... Intake of total protein, animal protein, and MUFAs was inversely associated with incident frailty. Promoting the intake of these nutrients might reduce frailty"
• Brain levels of vitamin B12 decrease with age and are prematurely low in people with autism and schizophrenia - Science Daily, 1/23/16 - "Vitamin B12 levels in the brain are significantly decreased in the elderly and are much lower in individuals with autism or schizophrenia, as compared to their peers at similar ages ... healthy elderly people in the age range of 61-80 have about three times lower levels of total brain B12 than younger age groups, which is a result of normal aging" - See vitamin B12 at Amazon.com.
• B12 deficiency a concern for long-term care - Science Daily, 1/19/16 - "A high proportion of older adults entering long-term care homes in Ontario are B12 deficient, with more developing deficiencies over the course of their first year in residence ... Untreated B12 deficiency will eventually lead to anemia and neurologic complications such as unsteady gait and paralysis. Low levels of the vitamin have been found to be associated with depression and dementia, increased confusion, lethargy and even osteoporosis" - See vitamin B12 at Amazon.com.
• Older adults: Double your protein to build more muscle - Science Daily, 1/30/15 - "Current US recommendations for daily dietary protein intake are 0.8 grams/kilogram of body weight (roughly 62 g of protein per day for a 170-pound person). Previous research has shown that older adults need a protein intake of at least 0.40 g/kg of body weight at each meal (roughly 31 g of protein per meal or 93 g per day for a 170-pound person) to encourage maximum protein synthesis. This represents a significantly higher amount of protein than the recommended dietary allowance (RDA) suggests ... The research team studied 20 healthy adults between 52-75 years of age, randomly assigning them to one of four groups over a four-day test period ... while the distribution of protein across meals did not make a significant impact, total amount of protein consumed"

• Vitamin D Deficiency in Elderly People in Swedish Nursing Homes is Associated with Increased Mortality - Eur J Endocrinol. 2014 Feb 11 - "with the subjects in Q4(25(OH)D3 >48 nmol/l), HR (with 95% confidence interval) for mortality was 2.02 (1.31-3.12) in Q1(25(OH)D3 <29 nmol/l) (p<0.05), 2.03 (1.32-3.14) in Q2(25(OH)D3 30-37 nmol/l) (p<0.05) and 1.6 (1.03-2.48) in Q3(25(OH)D3 38-47 nmol/l) (p<0.05). The mean 25(OH)D3 concentration was 40.2 nmol/l (Standard Deviation (SD) 16.0) and 80% had 25(OH)D3 below 50 nmol/l" - See vitamin D3 at Amazon.com.  In table form:

  D3 (nmol/l)	Mortality
  Greater than 48	1.0 (baseline)
  less than 29	2.02
  30 - 37	2.03
  38 - 47	1.6

• Geriatrics Society Guidelines: Vitamin D May Prevent Falls - Medscape, 1/10/14 - "Calcium absorption, healthy bone density, and physical function all require adequate vitamin D levels, and calcium is also vital for bone health. In addition, low Vitamin D levels are linked to muscle weakness, loss of bone strength, and falls and fractures ... For the population of older adults, a total average daily intake from all sources (diet, supplement, and sunlight) of 4000 IU will ensure that 90% of the population will achieve serum 25(OD) D levels of 30 ng/mL ... This is the serum level that will maximize the protection from falls and fractures that vitamin D can provide ... To maximize absorption, the vitamin D supplements should be taken with meals that provide some fat or oils ... clinicians generally do not need to measure vitamin D levels in patients receiving adequate supplementation" - See vitamin D at Amazon.com.
• Effect of resistance-type exercise training with or without protein supplementation on cognitive functioning in frail and pre-frail elderly: secondary analysis of a randomized, double-blind, placebo-controlled trial - Mech Ageing Dev. 2013 Dec 26 - "Physical activity has been proposed as one of the most effective strategies to prevent cognitive decline. Protein supplementation may exert an additive effect. The effect of resistance-type exercise training with or without protein supplementation on cognitive functioning in frail and pre-frail elderly people was assessed in a secondary analysis. Two 24-week, double-blind, randomized, placebo-controlled intervention studies were carried out in parallel. Subjects performed a resistance-type exercise program of two sessions per week (n=62) or no exercise program (n=65). In both studies subjects were randomly allocated to either a protein (2×15g daily) or a placebo drink ... In frail and pre-frail elderly resistance-type exercise training in combination with protein supplementation improved information processing speed (changes in domain score 0.08±0.51 versus -0.23±0.19 in the non-exercise group, p=0.04). Exercise training without protein supplementation was beneficial for attention and working memory (changes in domain scores 0.35±0.70 versus -0.12±0.69 in the non-exercise group, p=0.02)" - See protein drinks at Amazon.com.
• Low thyroid levels may signal heightened risk of death in hospitalized patients - Science Daily, 10/30/13 - "When older individuals have low levels of thyroid hormones, particularly T3, it reflects that the body is weak and more susceptible to the harmful effects of disease ... As a result, older individuals who have a reduced ability to synthesize T3 hormones have a higher rate of mortality, both in the short- and long-term" - See T3 at International Anti-aging Systems.
• Vitamin D and Physical Performance in Older Men and Women Visiting the Emergency Department Because of a Fall: Data from the Improving Medication Prescribing to reduce Risk Of FALLs (IMPROveFALL) Study - J Am Geriatr Soc. 2013 Oct 1 - "Physical performance was assessed using the Timed Up and Go Test, the Five Time Sit to Stand Test, handgrip strength, and the tandem stand test ... In men, higher serum 25(OH)D concentration was significantly associated with better handgrip strength (regression coefficient (B) = 3.86, 95% confidence interval (CI) = 2.04-5.69), faster TUG time (B = -2.82, 95% CI = -4.91 to -0.73), and faster FTSS time (B = -3.39, 95% CI = -5.67 to -1.11). In women, higher serum 25(OH)D concentration was significantly associated with faster TUG time" - See vitamin D at Amazon.com.
• A randomized study on the effect of vitamin D3 supplementation on skeletal muscle morphology and vitamin D receptor concentration in older women - J Clin Endocrinol Metab. 2013 Oct 9 - "To determine whether vitamin D3 4000 IU/d alters muscle fiber cross-sectional area (FCSA) and intramyonuclear VDR concentration over 4 months ... Vitamin D3 supplementation increased intramyonuclear VDR concentration by 30% and increased muscle fiber size by 10% in older, mobility-limited, vitamin D-insufficient women" - See vitamin D at Amazon.com.
• Low vitamin D status is associated with reduced muscle mass and impaired physical performance in frail elderly people - Eur J Clin Nutr. 2013 Aug 14 - "Serum 25-hydroxyvitamin D (25(OH)D) status has been associated with muscle mass, strength and physical performance in healthy elderly people. Yet, in pre-frail and frail elderly people this association has not been studied ... study included 127 pre-frail and frail elderly people in The Netherlands ... appendicular lean mass (ALM) ... In this frail elderly population, 25(OH)D status is low and suggests a modest association with reduced ALM and impaired physical performance. In addition, vitamin D intake tended to be associated with impaired physical performance" - See vitamin D at Amazon.com.
• Too Little Vitamin D May Hasten Disability as You Age - WebMD, 7/17/13 - "It's estimated that as many as 90 percent of older people are vitamin D-deficient ... Among participants aged 65 to 88, those with the lowest vitamin D levels were 1.7 times as likely to have at least one physical limitation as those with the highest vitamin D levels. Among participants aged 55 to 65, those with the lowest vitamin D levels were twice as likely to have at least one physical limitation as those with the highest vitamin D levels" - [Abstract] - See vitamin D at Amazon.com.
• Low vitamin D status is an independent predictor of increased frailty and all-cause mortality in older men: the Health In Men Study - J Clin Endocrinol Metab. 2013 Jun 20 - "4203 older men aged 70-88 years in Perth, Western Australia ... After a mean period of 5.3 years, the adjusted odds ratio of being frail at follow-up for men with low vitamin D and having zero deficit at baseline (FRAIL scale = 0) was 1.56 (95% CI 1.07 to 2.27). Low vitamin D also predicted all-cause mortality over a period of up to 9.2 years (hazards ratio 1.20, 95% CI 1.02 to 1.42), independent of baseline frailty and other covariates" - See vitamin D at Amazon.com.
• Associations Between Frailty and Serum 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Concentrations in Older Australian Men: The Concord Health and Ageing in Men Project - J Gerontol A Biol Sci Med Sci. 2013 May 8 - "Cross-sectional analysis of the Concord Health and Ageing in Men Project, a large epidemiological study conducted in Sydney, Australia, between January 2005 and May 2007 ... 1,25-dihydroxyvitamin D and 25-hydroxyvitamin D levels were independently associated with frailty in older men. This suggests that there might be a number of different biological mechanisms for how low vitamin D status might contribute to the frailty syndrome. In addition, the possibility that improving vitamin D status may specifically influence the incidence and progression of frailty needs to be explored" - See vitamin D at Amazon.com.
• Associations Between Vitamin D and Self-Reported Respiratory Disease in Older People from a Nationally Representative Population Survey - J Am Geriatr Soc. 2013 May 6 - "Health Survey for England 2005 ... Low serum 25(OH)D concentrations are associated with respiratory disease. Ensuring adequate 25(OH)D levels is of public health importance for older populations living in northern latitudes and may be an effective way to prevent concurrent respiratory infections and related complications in older people" - See vitamin D at Amazon.com.
• Association of Marine-Origin n-3 Polyunsaturated Fatty Acids Consumption and Functional Mobility in the Community-Dwelling Oldest Old - J Nutr Health Aging. 2013;17(1):82-9 - "Multivariate logistic regression analysis revealed that a lower habitual intake of EPA+DHA was significantly associated with poor functional mobility in men but not in women (OR (95%CI) per 1 SD increase of EPA+DHA intake; 0.55 (0.33-0.91), 0.88 (0.59-1.32), men and women respectively)" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• This is your brain on exercise - nbcnews.com, 11/26/12 - "Seniors who fit in the most daily physical activity – from raking leaves to dancing – can have more gray matter in important brain regions ... The scientists have images that show people who were the most active had 5 percent more gray matter than people who were the least active. Having more little gray brain cells translates into a lower risk of Alzheimer’s disease, other studies have shown ... the MRIs showed the differences were in areas of the brain like the hippocampus, which is heavily damaged in Alzheimer’s disease ... No pharmaceutical drug on the market has been shown to have these effects on the brain -- not a single drug ...  And exercise is available to anyone ... And it doesn’t cost anything"
• Feel-good hormone helps jog memory, finds study of seniors - Science Daily, 11/8/12 - "Half of the test participants had first taken a placebo and the remainder had taken Levodopa. This substance, also known as L-DOPA, is able to reach the brain from the bloodstream, and there it is converted into dopamine ... after six hours memory performance changed. Test subjects with Levodopa recognised up to 20 per cent more photos than the members of the comparison group. The ratio between the amount of Levodopa taken and the body weight of the test subjects proved to be decisive for an optimal dose" - Yeah but I think if I remember correctly, you buildup a tolerance to Levodopa and it no longer works.  IAS sells it.
• Dietary protein and beef consumption predict for markers of muscle mass and nutrition status in older adults - J Nutr Health Aging. 2012;16(9):784-90 - "Beef intake was positively associated with mid-arm muscle area, and protein intake was positively associated with nutrition status, calf circumference, and BMI in older adults. Consuming lean cuts of beef in moderation may be a healthy way in which older adults can increase protein intake, preserve muscle mass and improve nutrition status"
• Low levels of vitamin D are associated with mortality in older adults - Science Daily, 10/2/12 - "We observed vitamin D insufficiency (defined as blood levels <20 ng/ml), in one third of our study participants. This was associated with nearly a 50 percent increase in the mortality rate in older adults" - See vitamin D at Amazon.com.
• Caffeine boosts power for elderly muscles - Science Daily, 6/29/12 - "For adults in their prime, caffeine helps muscles to produce more force ... With the importance of maintaining a physically active lifestyle to preserve health and functional capacity, the performance-enhancing benefit of caffeine could prove beneficial in the aging population"
• Fruit and vegetable intake, physical activity, and mortality in older community-dwelling women - J Am Geriatr Soc. 2012 May;60(5):862-8 - "During 5 years of follow-up, 82 (11.5%) participants died. Measured continuously, physical activity improved survival (HR = 0.52, 95% CI = 0.41-0.66, P < .001). The most active women were more likely to survive than the least physically active women (HR = 0.28, 95% CI = 0.13-0.59, P < .001). Continuous measures of carotenoids improved survival (HR = 0.67, 95% CI = 0.51-0.89, P = .01). Women in the highest tertile of total carotenoids were more likely to survive those in the lowest (HR = 0.50, 95% CI = 0.27-0.91, P = .03). When examined in the same model, continuous measures of physical activity (HR = 0.54, 95% CI = 0.42-0.68, P < .001) and carotenoids (HR = 0.76, 95% CI = 0.59-0.98, P = .04) predicted survival during follow-up" - See Jarrow Formulas, CarotenALL at Amazon.com.
• Low Vitamin D Raises Mortality Risk in Nursing Home Patients - Medscape, 3/12/12 - "The first prospective cohort study to examine vitamin D deficiency and mortality among elderly female nursing home patients found that nearly all have 25(OH)D levels below the limits of normal, and that those with the lowest vitamin D levels were most likely to die within the next 27 months" - See vitamin D at Amazon.com.
• Omega-3 may enhance benefits of strength training for the elderly - Nutra USA, 1/6/12 - "fish oil may be an attractive supplement for the elderly to maximize their neuromuscular responses to strength training, which is important to life quality" - [Abstract] - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• Effect of vitamin d supplementation on muscle strength, gait and balance in older adults: a systematic review and meta-analysis - J Am Geriatr Soc. 2011 Dec;59(12):2291-300 - "Supplemental vitamin D with daily doses of 800 to 1,000 IU consistently demonstrated beneficial effects on strength and balance. An effect on gait was not demonstrated, although further evaluation is recommended" - See vitamin D at Amazon.com.
• Effect of essential amino acid supplementation on quality of life, Amino acid profile and strength in institutionalized elderly patients - Clin Nutr. 2011 May 31 - "Oral supplementation with essential amino acids improved several determinants of quality of life in institutionalized elderly patients, including depressive symptoms, nutrition, muscle function and daily life activity" - See BCAA products at Amazon.com.  Another amino acid study:
  • Amino acid supplement makes mice live longer - Science Daily, 10/5/10 - "leucine, isoleucine, and valine extend the life span of single-celled yeast ... Animals that were given the extra amino acids over a period of months lived longer, with a median life span of 869 days compared to 774 days for untreated control animals, the researchers report. That's an increase of 12 percent ... The findings in older mice suggest that the supplementary mixture may be specifically beneficial for those who are elderly or ill"
• B vitamin status, dietary intake and length of stay in a sample of elderly rehabilitation patients - J Nutr Health Aging. 2011;15(6):485-9 - "The age was 80 +/- 8 year (mean +/- SD), BMI 26.4 +/- 6.8 kg/m2 and MNA score 22 +/- 3 indicating some risk of malnutrition. Deficiencies of vitamins B6, B12 and folate were found in 30, 22 and 5 subjects respectively. Length of stay was positively correlated with age and MMA (Spearman's correlation 0.4, p<0.01 and 0.28, p<0.05 respectively) and negatively correlated with albumin, vitamin B6 and MNA score (Spearman's correlation -0.35, -0.33 and -0.29, p<0.05). After adjustment for age and sex, ln vitamin B6 and ln MMA concentrations were significant in predicting ln LOS (p=0.006 and p=0.014 respectively). Conclusion: The study indicates a high risk of vitamin B deficiencies in the elderly and suggests that deficiencies of vitamins B6 and B12 are associated with length of stay. This is concerning as B vitamin status is rarely fully assessed"
• A Randomized Controlled Trial of the Effects of Vitamin D on Muscle Strength and Mobility in Older Women with Vitamin D Insufficiency - Medscape, 1/4/11 - "In conclusion, vitamin D supplementation in older individuals receiving calcium improved hip muscle strength and mobility in participants with low baseline values. Given the importance of maintaining physical performance in older people to maintain a healthy and independent life in the community, vitamin D should be added to those with insufficiency or deficiency to improve muscle function" - See vitamin D at Amazon.com.
• Dietary omega-3 fatty acid supplementation increases the rate of muscle protein synthesis in older adults: a randomized controlled trial - Am J Clin Nutr. 2010 Dec 15 - "Omega-3 fatty acids stimulate muscle protein synthesis in older adults and may be useful for the prevention and treatment of sarcopenia" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• Dehydroepiandrosterone Combined with Exercise Improves Muscle Strength and Physical Function in Frail Older Women - Medscape, 11/10/10 - "The current study found an improvement in strength and function with DHEA supplementation, but exercise, even at low intensity, may have been a requisite for this effect, as others have found in nonfrail subjects ... DHEA supplementation increased the concentration of all sex hormones studied, indicating a good therapeutic response. DHEAS levels increased five times, equal to those seen in a typical young adult[44] and similar to increases seen in other studies of older adults using 50-mg/d supplementation with DHEA.[10,12,17,18,20,32,45] Other studies have reported increases in estrogen and testosterone levels similar to those reported here.[10,17,18,45] The increases in estradiol and estrone levels reached those seen in premenopausal women, and the levels of testosterone were greater than in premenopausal women" - See DHEA at Amazon.com.
• A randomized controlled trial of the effects of vitamin d on muscle strength and mobility in older women with vitamin d insufficiency - J Am Geriatr Soc. 2010 Nov;58(11):2063-8 - "Vitamin D therapy was observed to increase muscle function in those who were the weakest and slowest at baseline. Vitamin D should be given to people with insufficiency or deficiency to improve muscle strength and mobility" - See vitamin D at Amazon.com.
• Vitamin D Treatment for the Prevention of Falls in Older Adults (printer-friendly) - Medscape, 9/30/10 - "In summary, vitamin D supplementation is an effective strategy for reducing falls in older adults and should probably be incorporated into the clinical practice of providers caring for older adults, especially those at risk for falling. Although the effect appears to be modest, possibly because of inadequate dosing, vitamin D is inexpensive and well tolerated; a slight reduction in falls with vitamin D supplementation might lead to a significant decrease in the costs associated with fall morbidity and mortality" - See vitamin D at Amazon.com.
• Dehydroepiandrosterone combined with exercise improves muscle strength and physical function in frail older women - J Am Geriatr Soc. 2010 Sep;58(9):1707-14 - "DHEA supplementation resulted in gains in lower extremity strength (from 459 +/- 121 N to 484 +/- 147 N; P=.01). There was also improvement in Short Physical Performance Battery score, a composite score that focuses on lower extremity function, in those taking DHEA (from 10.1 +/- 1.8 to 10.7 +/- 1.9; P=.02). There were significant changes in all hormone levels, including DHEAS, estradiol, estrone, and testosterone, and a decline in sex hormone-binding globulin levels in those taking DHEA ... CONCLUSION: DHEA supplementation improved lower extremity strength and function in older, frail women involved in a gentle exercise program of chair aerobics or yoga. No changes were found in BMD either due to small sample size, short duration of study or no effect. The physical function findings are promising and require further evaluation as frail women are at high risk for falls and fracture" - See DHEA at Amazon.com.
• Low vitamin D linked to the metabolic syndrome in elderly people - Science Daily, 7/1/10 - "vitamin D inadequacy may be a risk factor for the metabolic syndrome, a condition that affects one in four adults ... Because the metabolic syndrome increases the risk of diabetes and cardiovascular disease, an adequate vitamin D level in the body might be important in the prevention of these diseases ... The researchers found a 48 percent prevalence of vitamin D deficiency" - See vitamin D at Amazon.com.
• Vitamin D deficiency and frailty in older Americans - J Intern Med. 2010 Apr 28 - "Nationally representative survey of noninstitutionalized US residents collected between 1988 and 1994. Results. 25-Hydroxyvitamin D deficiency, defined as a serum concentration <15 ng mL(-1), was associated with a 3.7-fold increase in the odds of frailty amongst whites and a fourfold increase in the odds of frailty amongst non-whites. This association persisted after sensitivity analyses adjusting for season of the year and latitude of residence, intended to reduce misclassification of persons as 25-hydroxyvitamin D deficient or insufficient. Conclusion. Low serum 25-hydroxyvitamin D concentrations are associated with frailty amongst older adults" - See vitamin D at Amazon.com.
• Better vitamin D status could mean better quality of life for seniors - Science Daily, 4/25/10 - "When the results were tabulated, participants with the highest levels of 25-hydroxyvitamin D had better physical function. And, although physical function declined over the course of the study, it remained significantly higher among those with the highest vitamin D levels at the beginning of the study compared to those with the lowest vitamin D levels. The scientists were not surprised to learn that, in general, vitamin D consumption was very low in this group of otherwise healthy seniors. In fact, more than 90% of them consumed less vitamin D than currently recommended, and many were relying on dietary supplements" - See vitamin D at Amazon.com.
• Dietary Antioxidants Could Help Preserve Muscle Strength in Older Adults - Medscape, 11/23/09 - "In a study in older adults, dietary intake of vitamins C and E was linked with muscle strength, leading the researchers to suggest at a meeting in Atlanta this past weekend that a diet high in antioxidants could play an important role in preserving muscle function in older adults ... Muscle strength is really a marker of aging ... Muscle strength starts declining when people are in their 40s, but it decreases dramatically after age 60 ... At this point, it's not clear whether vitamins C and E specifically help preserve muscle strength, or if intake of these micronutrients is a marker of a healthy diet"
• Vitamin D May Help Prevent Falls - WebMD, 10/2/09 - "Taking vitamin D supplements, at a dose of 700-1,000 international units per day, may make falling 19% less likely for people aged 65 and older" - See vitamin D at Amazon.com.
• Active Older Adults Live Longer, Have Better Functional Status - Science Daily, 9/14/09
• CLA may protect against elderly muscle loss - Nutra USA, 7/24/09 - "Supplementation with conjugated linoleic acid (CLA) prevented age-related muscle loss in mice ... After six months the researchers note that both the trans-10 cis-12 and CLA-mix showed “significantly higher muscle mass, as compared to corn oil and cis-9 trans-11 CLA groups” ... Both groups also exhibited increased cellular energy production (ATP), as well as higher levels of the antioxidant enzymes catalase and glutathione peroxidase in the muscles, compared to the corn oil and cis-9 trans-11 CLA groups" - See conjugated linoleic acid at Amazon.com.
• Older People Need More Sun, Expert Urges - Science Daily, 5/11/09 - "His team found a high correlation between low vitamin D levels and the prevalence of metabolic syndrome. They found 94% of people in the study had a vitamin D (25-hydroxyvitamin D) deficiency or insufficiency. The results showed 42.3% of these people also had metabolic syndrome ... Vitamin D deficiency is becoming a condition that is causing a large burden of disease across the globe with particular deleterious impact among the elderly" - See vitamin D at Amazon.com.
• Vitamin D Deficiency in Older Men - J Clin Endocrinol Metab. 2009 Jan 27 - "Vitamin D deficiency is common in older men, and is especially prevalent in obese, sedentary men living at higher latitudes. Use of vitamin D supplements at levels reported here did not result in adequate vitamin D nutrition" - See vitamin D at Amazon.com.
• High-dose oral vitamin D(3) supplementation in the elderly - Osteoporos Int. 2008 Dec 20 - "Sixty-three elderly participants were randomized to three regimens of vitamin D supplementation: a 500,000-IU loading dose; the loading dose plus 50,000 IU/month; or 50,000 IU/month ... Large loading doses of vitamin D(3) rapidly and safely normalize 25OHD levels in the frail elderly. Monthly dosing is similarly effective and safe, but takes 3-5 months for plateau 25OHD levels to be reached" - See vitamin D at Amazon.com.
• L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial - Am J Clin Nutr. 2007 Dec;86(6):1738-44 - "Our study indicates that oral administration of levocarnitine produces a reduction of total fat mass, increases total muscular mass, and facilitates an increased capacity for physical and cognitive activity by reducing fatigue and improving cognitive functions" - See l-carnitine at Amazon.com.
• Multivitamin supplementation improves nutritional status and bone quality in aged care residents - Eur J Clin Nutr. 2007 Nov 28 - "multivitamin (MV) ... randomized to receive a daily MV or placebo (P) tablet for 6 months ... There was a trend towards a 63% lower mean number of falls in the MV vs P group"
• Low Vitamin D Levels Linked To Poor Physical Performance In Older Adults - Science Daily, 4/23/07 - "physical performance and grip strength were about five to 10 percent lower in those who had low levels of vitamin D ... Current recommendations call for people from age 50 to 69 to get 400 international units (IUs) of vitamin D per day and for those over age 70 ... Higher amounts of vitamin D may be needed for the preservation of muscle strength and physical function as well as other conditions such as cancer prevention"
• Zinc Supplementation May Decrease Incidence of Infections in the Elderly - Medscape, 3/13/07 - "After zinc supplementation, the incidence of infections was significantly lower, plasma zinc was significantly higher, and generation of tumor necrosis factor alpha and oxidative stress markers was significantly lower in the zinc-supplemented than in the placebo group" - See Zinc products at iHerb.
• Zinc supplementation decreases incidence of infections in the elderly: effect of zinc on generation of cytokines and oxidative stress - Am J Clin Nutr. 2007 Mar;85(3):837-44 - "After zinc supplementation, the incidence of infections was significantly lower, plasma zinc was significantly higher, and generation of tumor necrosis factor alpha and oxidative stress markers was significantly lower in the zinc-supplemented than in the placebo group"
• Vitamin D May Reduce Falls In Elderly Nursing Home Residents - Science Daily, 2/22/07 - "seniors taking a high daily dose of vitamin D experienced 72 percent fewer falls compared to those taking a placebo ... The dose that was most effective, 800 International Units per day, is higher than the dose typically prescribed to seniors" - See vitamin D at Amazon.com.
• A higher dose of vitamin d reduces the risk of falls in nursing home residents: a randomized, multiple-dose study - J Am Geriatr Soc. 2007 Feb;55(2):234-9 - "Nursing home residents in the highest vitamin D group (800 IU) had a lower number of fallers and a lower incidence rate of falls over 5 months than those taking lower doses. Adequate vitamin D supplementation in elderly nursing home residents could reduce the number of falls experienced by this high falls risk group"
• Effect of an enriched drink on cognitive function in frail elderly persons - J Gerontol A Biol Sci Med Sci. 2005 Feb;60(2):265-70 - "participants' cognitive function was assessed (word learning test [WLT], WLT delayed, category fluency [CF] ... After 6 months, significant differences were noted in changes of the WLT (0.9 +/- 0.3 vs -0.1 +/- 0.3; p =.014) and CF professions ... This study contributes to the evidence that nutritional supplementation may improve neuropsychological performance in frail elderly persons"
• Exercise Boosts Immunity in Elderly Men - WebMD, 8/27/04
• Taiji (Tai Chi) Improves Knee Strength and Force Control in the Elderly - Doctor's Guide, 9/2/03
• Early response to oral cobalamin therapy in older patients with vitamin B12 deficiency - Ann Med Interne (Paris) 2003 Mar;154(2):91-5 - "Our findings suggest that cyanocobalamin given orally during one week may be an effective treatment for cobalamin deficiency related to food-cobalamin malabsorption and nutritional deficiency and may avoid painful intra-muscular injections in older patients" - See vitamin B12 at Amazon.com.
• It's Never Too Late to Start Exercise - WebMD, 5/13/03
• Tai Chi Exercise Improves Balance and Mobility in Elderly Women - New Hope Natural Media, 2/13/03
• Strength or Endurance Training Does Little to Improve Cardiovascular Fitness in Older Women - Doctor's Guide, 8/8/02
• Pets Do Make A Difference For Patients In Long-Term Care Facilities - Intelihealth, 6/28/02
• Once-a-Week Workout Keeps Elderly Strong - WebMD, 5/16/02
• Older Adults Can Exercise Just Once A Week To Maintain Muscle Strength - Doctor's Guide, 5/13/02 - "skeletal muscle strength gains achieved during a 12-week progressive resistance training program would be maintained by resistance training once per week"
• Strength Training Improves Aerobic Power in Seniors - Doctor's Guide, 3/29/02
• Spirituality Prevents Depression in Old Age - WebMD, 2/19/02
• Nutrition Is A Key To Better Health For Elderly - Intelihealth, 8/20/01 - "Too many older people may be accepting a cognitive and immunological decline as a normal part of aging, when it may reflect a deficiency in essential nutrients like vitamins and minerals ... a nutrient supplement with modest amounts of 18 vitamins, minerals and trace elements could improve cognitive function in apparently healthy people over 65 ... How might nutrients improve brain function? One possibility is that taking a modest nutrient supplement daily can improve immune function"
• Want to Stay Mentally Fit? -- Get Out There and Make Friends - WebMD, 7/5/01
• Too Many Elderly Lacking in Vitamin D, Study: Defiency All Too Common, Could Be Cause of Muscle Weakness - WebMD, 5/16/01 - "many elderly patients who are bedridden or in wheelchairs may actually be suffering from muscle weakness caused by severe, but easily treatable, vitamin D deficiencies ... The researcher suggests that even twice that amount may not be enough in chronically ill and even healthy older patients, because absorption of the vitamin tends to be impaired with age"
• Older Women Who Keep Active Have Lower Risk for Mental Decline - WebMD, 5/9/01 - "women who walked the most were the least likely to suffer a decline in thought processes and that there was a direct relationship between activity and mental function: As the amount of walking or calories burned per week rose, the risk for loss of mental abilities declined"
• Elderly Lack Adequate Levels of Vitamin D - Medscape, 5/8/01  - "Despite the fact that most of patients were daily receiving multivitamins containing 400-800 IU of vitamin D, investigators found that the majority had low levels of the nutrient ... Vitamin D increases calcium absorption by 30% to 80% and is therefore crucial in order to maintain strong bones"
• Tai Chi Keeps Seniors Going Strong, Martial Art Form Helps Balance, Independence - WebMD, 5/2/01
• Fatty Fish Cuts Risk Of Death From Heart Attack In Elderly - Intelihealth, 3/1/01
• Supplements Help the Frail Elderly - Nutrition Science News, 3/00
• A Supplement Plan for Seniors - Nutrition Science News, 12/99

Other News:

• One in four seniors have superbugs on their hands after a hospital stay, new research finds - Science Daily, 3/14/16 - "Researchers tested the same patients' hands after two weeks and then monthly, for up to six months or until their discharge home from the post-acute care facility. During the follow-up visits, they found not only did these organisms persist, but even more seniors acquired superbugs on their hands -- up from one in four (24.1 percent) to more than one in three (34.2 percent) ... A high level of MDROs on patient hands increases the chance that these superbugs will be transmitted to other frail patients and health care workers" - The first thing I do whenever I return home from the hospital or doctor's office is throw my closes in the laundry and take a shower.
• Lipid-Lowering Drugs Associated With Slower Motor Decline in the Elderly Adults - J Gerontol A Biol Sci Med Sci. 2013 Oct 4 - "We investigated the relationship between lipid-lowering drugs (LLDs) use and decline in walking speed (WS) in older adults ... 4,009 community-dwelling men and women, aged ≥65 years at baseline, are drawn from the Dijon (France) center of the Three-City study ... WS decline was 25% slower in LLDs users ... Fast WS declined less in those on LLDs, suggesting that the effect of LLDs, statins in particular, extend beyond that on cardiovascular disease in the elderly persons"
• Late Life Leisure Activities and Risk of Cognitive Decline - J Gerontol A Biol Sci Med Sci. 2012 Aug 9 - "Leisure activities in old age may protect against cognitive decline for both women and men, and different types of activities seem to benefit different cognitive domains"
• Cold homes cost lives, experts argue - Science Daily, 5/13/11 - "Marmot's report identifies three gains that could be achieved by improving the insulation in British homes. These are saving lives, protecting the environment and reducing health inequalities ... While elderly people living in cold homes are more prone to heart and lung disease, cold homes can affect health at any age, say the authors. Children are more likely to suffer from breathing problems and adolescents living in a cold house have an increased risk of mental health problems"
• Blood pressure drug shows some muscle: Researchers discover losartan protects against loss of old or damaged muscle - Science Daily, 5/11/11 - "Using geriatric mice, a Johns Hopkins research team has shown that losartan, a commonly used blood pressure drug, not only improves regeneration of injured muscle but also protects against its wasting away from inactivity ... To investigate losartan's role in muscle injury regeneration in the context of aging, the Hopkins team worked with 40 mice which, at 21-months old, were considered geriatric. After treating half of those animals for a week to water laced with losartan, they injected a chemical toxin into all the animals' shin muscles. The researchers examined the stained muscle tissue under a microscope at four days and again at 19 days, looking for signs of regeneration: small fibers with larger-than-usual nuclei. After four days, they saw no difference in the number of regenerating fibers between the losartan-treated mice and those not treated. However, after 19 days, the losartan-treated mice had about 10 to 15 percent of scar tissue formation compared with 30 to 40 percent of scar tissue formation in those not treated ... Again, using 21-month-old mice, half treated with losartan and half not, the team this time clipped the hind right foot of the mice to their knees, immobilizing just the shin muscles; otherwise, the mice were normally active ... After 21 days, the animals' shin muscles were weighed and compared under a microscope. The animals not treated with losartan lost 20 percent of the mass of their immobilized shin muscles. However, the losartan-treated animals lost virtually no mass, according to Tyesha Burks, a graduate student of Human Genetics, Johns Hopkins University School of Medicine ... "When we saw that the loss of muscle fibers was completely prevented by losartan therapy, it was quite mind-blowing," Cohn says" - Note:  Losartan is an ARB as is telmisartan which may be superior.  Maybe future studies will tell whether telmisartan has the same muscle loss prevention characteristics.  I'm guessing it will.
• Walking speed associated with survival in older adults - Science Daily, 1/4/11 - "Predicted years of remaining life for each sex and age increased as gait speed increased, with a gait speed of about 0.8 meters [2.6 feet]/second at the median [midpoint] life expectancy at most ages for both sexes. Gait speeds of 1.0 meter [3.3 feet]/second or higher consistently demonstrated survival that was longer than expected by age and sex alone. In this older adult population the relationship of gait speed with remaining years of life was consistent across age groups, but the absolute number of expected remaining years of life was larger at younger ages,"
• Beneficial Effects of Testosterone for Frailty in Older Men are Short-Lived - Doctor's Guide, 11/5/10 - "The beneficial effects of 6 months of testosterone treatment on muscle mass, strength, and quality of life (QOL) in frail elderly men are not maintained at 6 months post-treatment"
• Higher Blood Pressure Is Associated With Higher Handgrip Strength in the Oldest Old - Am J Hypertens. 2010 Sep 2 - "In middle-aged subjects, BP and handgrip strength were not statistically significantly associated. In oldest old subjects, higher systolic BP (SBP), mean arterial pressure (MAP), and pulse pressure (PP) were associated with higher handgrip strength after adjusting for comorbidity and medication use (all P < 0.02). Furthermore, in oldest old subjects, changes in SBP, MAP, and PP after 4 years was associated with declining handgrip strength"
• Low Testosterone Tied to Frailty in Older Men - Medscape, 4/26/10 - "In general, men with total testosterone levels below the median were more likely to be frail. Moreover, lower levels of free testosterone were tied to a greater risk of becoming frail over the next four to seven years"
• High-blood-pressure treatment for the over-80s too aggressive, warns expert - Science Daily, 12/22/09 - "This review includes data from two new trials which looked specifically at the effect of antihypertensive drugs in people over the age of 80. Interestingly, the only trial that found a significant reduction in mortality was the most conservative in terms of number of drugs and dose of drugs allowed. The treatment regime involved three easy steps, with a target blood pressure of 150/80 mmHg"
• Dance Your Way To Successful Aging - Science Daily, 4/10/09
• Older Americans Take Risky Drug Combos - WebMD, 12/23/08
• Surfing the Web Stimulates Older Brains - WebMD, 10/14/08 - "Middle-aged to older adults who know their way around the Internet had more stimulation of decision-making and complex reasoning areas of the brain than peers who were new to web surfing ... reading didn’t stimulate the same number of brain areas as Internet searching"
• Optimal protein intake in the elderly - Clin Nutr. 2008 Sep 24 - "It appears that an intake of 1.5gprotein/kg/day, or about 15-20% of total caloric intake, is a reasonable target for elderly individuals wishing to optimize protein intake in terms of health and function"
• Anxiety Often Missed in Elderly - WebMD, 5/22/06
• Risks Of Taking Sedatives For Insomnia In Older People May Be Greater Than The Benefits - Science Daily, 11/11/05
• Chronic Infection May Contribute to Frailty in Older Women - Doctor's Guide, 6/9/05
• Treating Depression in Elderly Helps Body Too - WebMD, 3/16/05 - "Elderly people who get treated for depression appear to benefit physically"
• Treating Depression Can Help Slow Physical Decline in Older Adults - Doctor's Guide, 3/14/05 - "Successful treatment of depression not only improves older adults' emotional health, but also helps them perform such daily activities as remembering to take medications"
• Activity Helps Seniors Think, Sleep Better - WebMD, 12/14/04
• Elderly Experience Long-term Cognitive Decline After Surgery - Science Daily, 10/29/04
• Elderly Who Exercise Some, Live Longer - WebMD, 7/15/04
• Dementia Often Undiagnosed in Clinical Settings - Doctor's Guide, 7/16/04
• Apathy May Be a Common Characteristic of Dementia - Clinical Psychiatry News, 12/03
• Many Assisted-Living Residents Not Getting Depression Help - Psychiatric News, 11/21/03
• Chronic Diseases Significantly Associated with Increased Risk of Falls in Elderly Women - Doctor's Guide, 9/29/03
• Tai Chi Each Day Keeps Shingles Away - WebMD, 9/22/03
• Fluoroquinolone Resistance 'Rampant' in Nursing Homes - Doctor's Guide, 9/15/03
• Weight Loss in Elderly May Be Sign of Neurologic Decline - Clinical Psychiatry News, 9/03
• Anemia in Elderly Linked to Declines - WebMD, 7/25/03 - "Elderly people with anemia have twice the risk of experiencing physical declines that can end up robbing them of their independence ... the findings should help call attention to a condition that is underdiagnosed and undertreated in elderly populations ... anemia can often be caused by an underlying disease such as cancer or kidney failure or by treatments for these diseases. Poor nutrition is a less common cause among the elderly, and no cause can be identified in about 30% of cases ... the diagnosis of anemia among elderly patients has not been a priority in the past because there were no effective treatments for the condition. That changed, however, with the introduction of epoetin alfa ... The injectable drug is marketed under the brand names Epogen and Procrit"
• Atypical Antipsychotic Drugs Effective for Elderly Patients with Dementia - Doctor's Guide, 6/25/03
• Identification Of Risk Factors In Depression In The Elderly Could Improve Public Health - Doctor's Guide, 6/16/03 - "Five factors - bereavement, sleep disturbance, disability, prior depression and female gender - have been identified as risk factors for depression in people aged fifty years or more"
• Risperidone May Prevent Falls in Dementia Patients - Clinical Psychiatry News, 6/03
• Benzodiazepines Linked to Declines in Elderly - Doctor's Guide, 5/20/03
• Tramadol/Acetaminophen Effective in Elderly Patients with Chronic Back Pain - Doctor's Guide, 5/20/03
• Telithromycin Effective in Treating Elderly Patients with Community-Acquired Pneumonia - Doctor's Guide, 5/20/03
• Health Info for “Surfing Seniors” - Physician's Weekly, 5/19/03
• New Guidelines Urge Individualized Care for Elderly Diabetics - Doctor's Guide, 5/16/03
• Simple Test Gauges Functioning of Elderly - Doctor's Guide, 5/16/03
• Caregivers Feel Helpless, Need Help - WebMD, 5/14/03
• Use Benzodiazepines With Care in Elderly - Clinical Psychiatry News, 5/03
• Depression and Aging -Physician's Weekly, 4/21/03
• Elderly Ignored, Isolated in Nursing Homes - Psychiatric News, 4/18/03
• Depression, Pain Connection Should Be Assessed in Elderly - Psychiatric News, 4/18/03
• Study Finds Benefits In Home Care Hiring - Intelihealth, 4/16/03
• Flu Shots Cut Hospitalization in Elderly - WebMD, 4/2/03
• Alcohol Abuse Among the Elderly Is Serious Problem - Clinical Psychiatry News, 4/03
• Web Site to Help Seniors Get Drug-Cost Assistance - Clinical Psychiatry News, 4/03
• Fluoxetine Mildly Effective in Elderly Patients with Dysthymic Disorder - Doctor's Guide, 3/7/03
• Oral Mirtazapine Effective, Well-tolerated by Depressed Nursing-Home Patients - Doctor's Guide, 3/7/03 - See my mirtazapine page.
• Aripiprazole Effective in Reducing Psychotic Symptoms Associated with AD-related Dementia - Doctor's Guide, 3/6/03
• Multi-Trial Analysis Shows Risperidone Effective in Treating Dementia-Related Agitation, Aggression - Doctor's Guide, 3/6/03
• Non-aggressive Symptoms in Dementia Patients Also Respond to Risperidone - Doctor's Guide, 3/5/03
• Selective Serotonin Reuptake Inhibitors Don't Change Mood and Personality in Healthy Elderly - Doctor's Guide, 3/5/03
• Risperidone More Effective than Conventional Neuroleptics in Reducing Dementia Symptoms - Doctor's Guide, 3/4/03
• Diagnosing Depression In The Elderly - CBS News, 2/20/03
• Biological Marker [p-tau(231)] Could Differentiate Alzheimer's, Geriatric Depression - Doctor's Guide, 2/12/03
• Death by Flu Too Common Among Elderly - WebMD, 1/7/03
• Collaborative Intervention Effective in Late-Life Depression - Doctor's Guide, 12/11/02
• Nursing Homes Kill Thousands - Intelihealth, 10/15/02
• "Prehabilitatio" Aids Frail Elders Living At Home - Doctor's Guide, 10/4/02
• Occupational Therapy is Cost Effective, Significantly Improves Quality of Life for Seniors - Doctor's Guide, 8/20/02
• Doctors Study Why Elderly So Prone To Suicide, How To Help - Intelihealth, 7/23/02
• Exercise To Improve Balance Reduces Falls In Elderly - Doctor's Guide, 7/18/02
• Needleless Flu Shots Well Tolerated in Frail Elderly - Doctor's Guide, 5/15/02
• Prilosec (Omeprazole) Plus Calcium Carbonate Decreases Calcium Absorption In Elderly Women - Doctor's Guide, 5/14/02
• New Guidelines for Pain Control in Older Patients - Medscape, 5/14/02
• Postoperative Delirium In The Elderly May Be Prevented By A Medication-Based Protocol - Doctor's Guide, 5/10/02
• High Prevalence Of Sleep Problems Found In The Elderly - Doctor's Guide, 4/26/02
• Elderly Patients Having High-Risk Surgeries in U.S. Fare Better in More Experienced Hospitals - Doctor's Guide, 4/11/02
• Behavior Management Programs Help Seniors With Chronic Illnesses Sleep Better - Doctor's Guide, 4/4/02
• Cheaper Prescriptions Add Years to Life - WebMD, 3/29/02
• Cardiorespiratory Benefit Of Aerobic Exercise Applies To Older Patients Too - Doctor's Guide, 3/26/02
• Mixed Review For Geriatric Treatment - Intelihealth, 3/21/02
• Optimal Management of Psychosis & Agitation in the Elderly - Medscape, 3/20/02
• Keeping Seniors Independent - WebMD, 3/14/02 - "the average three-year decline in walking speed among those women who used ACE inhibitors was 10 times lower than it was in the other groups ... Researchers think several factors may explain these drugs' beneficial effect on delaying disability: ACE inhibitors increase blood flow to the muscles, reduce inflammation, and promote healthy eating habits and better nutrition by inhibiting a substance known to reduce appetite"
• New Index Developed to Assess Mortality Risk in the Elderly - Doctor's Guide, 3/12/02
• Post-Exercise Blood Pressure Reduction Clinically Relevant In Elderly Hypertensive Patients - Doctor's Guide, 3/12/02 - "They also experienced a 22-hour post-exercise blood pressure reduction. This result shows that low-intensity exercise is clinically relevant in elderly patients with hypertension"
• Lilly offers prescription card for low-income seniors - USA Today, 3/5/02
• Depression Harmful to Seniors' Health - WebMD, 2/13/02
• Persistent Mild Depression In Older Adults May Lower Immunity And Ability To Fight Off Disease, According To New Study - Intelihealth, 2/11/02
• 'Sex after 60' authors: Golden years can be best ones - USA Today, 1/31/02
• Seniors With The Blues May Be More Likely To Suffer From Heart Failure - Intelihealth, 1/31/02
• Psychotic Depression Late-Onset Condition in Elderly - Doctor's Guide, 1/2/02
• Simple Steps Can Combat Sleep Problems in Elderly - WebMD, 1/2/02
• Many Otherwise Healthy Elderly People Have Undiagnosed Diabetes - Doctor's Guide, 12/27/01
• Planning Ahead for Long-Term Care? - WebMD, 12/14/01
• Power Lifts Urged For Older Men - Intelihealth, 11/19/01 - "Older men with low levels of testosterone can literally haul themselves away from frailty by combining supplemental doses of the male sex hormone with fast-movement weight training ... At the end of the year, both exercise groups had improved, but lifters who got testosterone supplements improved more. The exercise-plus-supplement group had raised performance by close to sixfold, while the exercise-alone group had improved by almost fivefold"
• Unexplained Falls in Elderly Adults Could be Related to Treatable Heart Condition - Doctor's Guide, 11/2/01
• Expert Consensus Guidelines Published For Treatment Of Geriatric Depression - Doctor's Guide, 10/26/01
• Breakfast May Improve Memory in Healthy Elderly - Doctor's Guide, 10/24/01
• Seniors, Listen Up: There's No Reason to Dodge Colon-Cancer Tests - WebMD, 10/24/01
• Drug Company Offers Discount Plan for Elderly Poor - WebMD, 10/8/01
• Helping the Elderly Live at Home - WebMD, 9/28/01
• Common Allergy, Sleep Drug [Benadryl] May Cause Confusion in Elderly - WebMD, 9/28/01
• Antidepressant Risk for the Elderly - WebMD, 9/20/01 - "certain types of antidepressants increase the chance of bleeding in the stomach or intestines in the elderly, especially in those over the age of 80 ... We believe that the increased bleeding we saw is clinically significant for these two groups of people taking SSRIs, and that other antidepressant classes, such as the tricyclics"
• VA might loosen prescription rules - USA Today, 9/6/01
• The Challenge To Stay Well-Fed Increases With Age, Social Isolation, Physical Disabilities - Intelihealth, 8/23/01
• Depression and the Aging Man - WebMD, 6/27/01
• Afternoon Naps Fine For Healthy Elderly - Doctor's Guide, 6/11/01
• Gaboxadol Improves Sleep in Elderly - Doctor's Guide, 6/11/01
• Older People Benefit From Antihypertensive Therapy - Doctor's Guide, 5/20/01 - "across all clinical trials, treatment of hypertension in older adults reduces the risk of all types of major cardiovascular events, alone and in the aggregate, and even significantly reduces all- cause mortality"
• Diuretics And Calcium Antagonists Best Reduce Systolic Pressure In Untreated Elderly Hypertensives - Doctor's Guide, 3/19/01 - "Initial treatment of elderly people with essential hypertension should consist of thiazide diuretics or calcium-antagonists ... These are more effective than other agents at lowering systolic blood pressure"
• Bingo May B-1 Way To Sharpen Aging Minds - Intelihealth, 2/26/01
• Seroquel (Quetiapine Fumarate) Safe, Tolerable In Long-Term Treatment Of Psychosis In Elderly - Doctor's Group, 11/29/00
• Coping With More Than One Disorder - Intelihealth, 7/5/00
• FDA Approves Drug For Type Of Elderly Blindness - Intelihealth, 4/13/00
• Seroquel Safely And Effectively Treats Psychosis In Elderly - Doctor's Guide, 3/16/00
• Experts: Seniors Need Exercise - Intelihealth, 11/22/99