I added a lot of information to my karaoke page.  I think it is the most informative karaoke page in the Internet.  It took mega hours to research all that and there is no other site that I've found that tells you what you need to know.

Recent Longevity News for the seven days ending 1/16/08.  You should consult your doctor if you are taking any medications.

Calcium: Heart Risk for Older Women? - WebMD, 1/15/08 - "The women in the supplement group got 861 milligrams of calcium from diet per day, on average, boosting their total daily intake to 1,861. The placebo group averaged about 853 milligrams of calcium daily from their diet ... The risk of a heart attack was about 1.5 times greater for those in the supplement group, but the link did not reach statistical significance ... the calcium supplements may elevate blood calcium levels and possibly speed calcification in blood vessels"

Insulin-Resistant Cardiomyopathy - Medscape, 1/15/08 - "Increasing evidence points to insulin resistance as a primary etiologic factor in the development of nonischemic heart failure (HF) ... Epidemiological evidence suggests more than simply a correlation between insulin resistance and HF, demonstrating that insulin resistance precedes HF rather than occurring as a consequence of it ... Medications that work primarily by improving insulin sensitivity (metformin, thiazolidinediones [TZDs]) might theoretically be the most attractive therapies" - See my web page on Insulin and Aging.  I still take metformin and Actos (OffshoreRx1.com) even though I don't have diabetes.  I've had my HbA1C and a two hour glucose check and the numbers were bouncing off the lower limits.

• Insulin and Aging - Brown University - "Keep insulin levels low and cells are stronger, staving off infection and age-related diseases such as cancer, dementia and stroke"
• Resisting Insulin - USC Health Magazine Cover Story, Fall '06 - "Insulin, according to a slew of new studies, may play a role in everything from cancer to hypertension to cardiovascular disease"

Cholesterol Drug Has No Benefit in Trial - New York Times, 1/14/08 - "About 70 percent of patients who take Zetia do so in the form of Vytorin, which combines Zetia with the cholesterol drug Zocor ... the plaques actually grew somewhat faster in patients taking Zetia along with Zocor than in those taking Zocor alone. Patients in the trial who took the combination of Zetia and Zocor were receiving it in the form of Vytorin pills ... Patients should not be prescribed Zetia unless all other cholesterol drugs have failed"

Lipoic Acid Could Reduce Atherosclerosis, Weight Gain - Science Daily, 1/14/08 - "lipoic acid supplements reduced atherosclerotic lesion formation in two types of mice that are widely used to study cardiovascular disease, by 55 percent and 40 percent, respectively. The supplements were also associated with almost 40 percent less body weight gain, and lower levels of triglycerides in very low-density lipoproteins" - See alpha lipoic acid at Amazon.com.

Testosterone May Improve Mental Function - Science Daily, 1/14/08 - "higher testosterone levels in midlife have been linked to better preservation of tissue in some parts of the brain. And in older men, higher testosterone levels have been associated with better performance on cognitive tests ... Three studies linked impaired performance on cognitive tests with androgen deprivation therapy"

Eat Your Leafy Vegetables To Decreased Your Risk Of Cataracts - Science Daily, 1/14/08 - "When the participants were split into five groups based on the amount of lutein and zeaxanthin they consumed, those in the group who consumed the most (about 6,716 micrograms per day) had an 18 percent lower chance of developing cataracts than those who consumed the least (1,177 micrograms per day). The one-fifth who consumed the most vitamin E from food and supplements--about 262.4 milligrams per day--were 14 percent less likely than the one-fifth who got the least (4.4 milligrams per day)"

Low Testosterone Levels Associated With Risk Of Fracture In Men Over 60 - Science Daily, 1/14/08 - "Although low levels of estradiol and testosterone were associated with a higher risk of fracture in men over 60, only the effect of testosterone was independent of other risk factors, the authors conclude"

Better Bone Density Test - Dr. Weil, 1/14/08 - "If you’re a woman at risk for osteoporosis, I strongly recommend that you have a DEXA scan ... In addition, I recommend that all women supplement with 500 to 700 mg of calcium citrate in two divided doses taken with meals ... For men, I now suggest aiming for 500 mg from all sources. (Because higher amounts have been linked to increased risks of prostate cancer, men generally should avoid supplemental calcium.) I also recommend that both men and women take 1,000 IU of vitamin D3"

Soy linked to less belly fat in postmenopausal women - Nutra USA, 1/14/08 - "At the end of the trial there were no differences in the weight of women in both groups ... However, measures of subcutaneous abdominal fat were significantly different between the groups, with women in the soy group experiencing a 14.7 sq. cm reduction compared to a 22.9 sq. cm increase in the placebo group" - [Abstract]

Acrylamide In Food May Increase The Risk Of Breast Cancer - Science Daily, 1/11/08 - "Acrylamide is a chemical formed when frying, roasting, grilling or baking carbohydrate-rich foods at temperatures above 120°C. Acrylamide is thus found in a number of foods, such as bread, crisps, French fries and coffee. Tobacco smoking also generates substantial amounts of acrylamide ... The risk of breast cancer doubles with a tenfold increase in the acrylamide-haemoglobin level. A tenfold increase in the acrylamide-haemoglobin level corresponds more or less to the difference measured between the women with the lowest and highest exposure"

Most Effective Weight Loss Diet Revealed, According To New Study - Science Daily, 1/11/08 - "a high protein, low carbohydrate diet is most effective at reducing hunger and promoting weight loss, at least in the short term" - Note:  I still think it is unhealthy plus I graphed a similar study before.  See below and where the graph is headed.

Daidzein-rich supplement shows menopause potential - Nutra USA, 1/11/08 - "The new study, led by George Blackburn, assigned the subjects to receive daily supplements of the daidzein-rich isoflavone-aglycone (DRI) supplement at a dose of either 40 or 60 milligrams, or placebo for 12 weeks ... At the end of the study, the researchers report that the number of hot flushes in the group receiving the lower dose was reduced by 52 per cent, while the women receiving the higher dose experienced a 51 per cent reduction in the number of hot flushes. The placebo group reported a 39 per cent reduction in hot flush frequency" - [Abstract]

How Antioxidant Therapy May Play A Role In The Treatment Of Type 2 Diabetes - Science Daily, 1/11/08 - "Mice fed a high-fat, high-sucrose diet (HFHSD) developed insulin resistance and type 2 diabetes ... mitochondrial defects were present in diabetic, but not pre-diabetic glucose intolerant, mice ... ROS production coincided with mitochondrial dysfunction, and antioxidant treatment blocked the mitochondrial alterations in muscle cells"

Severe Weight Loss Can Be Caused By Chewing Gum, Doctors Report - Science Daily, 1/11/08 - "sorbitol consumption can cause not only chronic diarrhoea and functional bowel complaints but also considerable unintended weight loss (about 20% of usual body weight)"

Statins for All Adults with Diabetes? - WebMD, 1/10/08 - "One-third fewer people with type 1 or type 2 diabetes would suffer heart attacks or strokes if they took cholesterol-lowering statin drugs"

Surprise -- Cholesterol May Actually Pose Benefits, Study Shows - Science Daily, 1/10/08 - "Three days a week for 12 weeks, participants performed several exercises, including stretching, stationary bike riding and vigorous weight lifting ... At the conclusion of the study, the researchers found that there was a significant association of dietary cholesterol and change in strength. In general, those with higher cholesterol intake also had the highest muscle strength gain ... One possible explanation is through cholesterol’s important role in the inflammation process"

Metformin, Lifestyle Changes Effective in Antipsychotic-Induced Weight Gain - Medscape, 1/10/08 - "Lifestyle intervention plus metformin had the greatest effect on weight loss, and metformin alone was more effective than lifestyle intervention plus placebo in increasing insulin sensitivity and reversing weight gain in these patients with schizophrenia and significant weight gain from atypical antipsychotic agents"

CDC to Young Women: Take Folic Acid - WebMD, 1/10/08 - "All women, especially younger women ages 18-24 years, need to consume 400 micrograms of folic acid daily through supplements, fortified foods, or both in addition to a folate-rich diet to prevent serious birth defects"

Staying Active And Drinking Moderately Is The Key To A Long Life, Study Suggests - Science Daily, 1/9/08 - "ischaemic heart disease ... People who drank at least one drink a week and were physically active had a 44-50 per cent lower risk of IHD compared to physically inactive non-drinkers"

More support for lycopene's prostate benefits - Nutra USA, 1/9/08 - "At the end of the six month intervention period ... levels of prostate-specific antigen (PSA), a marker of prostate health, were reduced in the lycopene group showing improvements in health of the tissue. However, no changes were recorded in the placebo group ... Moreover, no enlargement of the prostate occurred in the lycopene group, whereas growth was observed in the placebo group" - [Abstract] - See Jarrow Lyco-Sorb at Amazon.com.

Fruit, Vegetable Eaters Have Fewer Strokes - WebMD, 1/9/08 - "Specifically, vitamin C levels may prove to be a good predictive indicator of stroke risk, independent of known risk factors such as age, smoking history, blood pressure, and cholesterol, they write"

FDA Goes After 'Natural' HRT Claims - WebMD, 1/9/08 - "The agency warned the pharmacies to cease marketing HRT containing estriol and to stop making claims that their products are "natural" or "bioequivalent" to standard HRT"

Statin Drugs May Cut Cancer Risk - WebMD, 1/8/08 - "The veterans were followed for five years, on average. During that time, 9% of those taking statins were diagnosed with cancer, compared with 13% of those not taking statins, VA records show"

Abstracts from this week's Doctor's Guide Nutrition/Dietetics plus abstracts from my RSS feeds (Click here for the journals, the PubMed ones at the top):

Thiazolidinediones-improving endothelial function and potential long-term benefits on cardiovascular disease in subjects with type 2 diabetes - J Diabetes Complications. 2008 Jan-Feb;22(1):62-75 - "Insulin-sensitizing agents such as thiazolidinediones have demonstrated a number of clinical benefits, including anti-inflammatory and antithrombotic properties, which may impact on the course of atherosclerosis. Recent studies have demonstrated that thiazolidinediones improve endothelial function in subjects with and without type 2 diabetes"

n-3 Fatty acids, hypertension and risk of cognitive decline among older adults in the Atherosclerosis Risk in Communities (ARIC) study - Public Health Nutr. 2008 Jan;11(1):17-29 - "Word Fluency Test (WFT) ... an increase of one standard deviation in dietary long-chain n-3 fatty acids (% of energy intake) and balancing long-chain n-3/n-6 decreased the risk of 6-year cognitive decline in verbal fluency with an odds ratio (95% confidence interval) of 0.79 (0.66-0.95) and 0.81 (0.68-0.96), respectively, among hypertensives. An interaction with hypertensive status was found for dietary long-chain n-3 fatty acids (g day-1) and WFT decline (likelihood ratio test, P = 0.06). This exposure in plasma cholesteryl esters was also protective against WFT decline, particularly among hypertensives (OR = 0.51" - See Mega Twin EPA at iHerb.

Effect of a daily supplement of soy protein on body composition and insulin secretion in postmenopausal women - Fertil Steril. 2007 Dec;88(6):1609-17 - "A daily supplement of soy protein prevents the increase in subcutaneous and total abdominal fat observed with an isocaloric casein placebo in postmenopausal women"

Sugar-sweetened soft drinks, diet soft drinks, and serum uric acid level: The third national health and nutrition examination survey - Arthritis Rheum. 2007 Dec 28;59(1):109-116 - "sugar-sweetened soft drink consumption is associated with serum uric acid levels and frequency of hyperuricemia, but diet soft drink consumption is not"

Sustained Tubulo-interstitial Protection in SHRs by Transient Losartan Treatment: An Effect of Decelerated Aging? - Am J Hypertens. 2008 Jan 10 - "Transient losartan treatment reduces cell-turnover not only acutely but also for a prolonged period after drug withdrawal. This results in the long-term in reduced aging and attenuated tubulo-interstitial damage, suggesting there exists a modulating effect of angiotensin II (ANGII)-antagonism on long-term cell turnover" - Note:  Losartan is an ARB.  I would think that telmisartan (also and ARB and my recommendation for hypertension) would give the same effect.

The effect of losartan on hemoglobin concentration and renal outcome in diabetic nephropathy of type 2 diabetes - Kidney Int. 2007 Dec 19 - "Compared with placebo, losartan treatment was associated with a significant decrease of hemoglobin, with the largest between-group difference at 1 year. After adjustment, there were significant relative risk reductions for losartan compared with placebo for ESRD and for ESRD or death regardless of the baseline hemoglobin even in those patients with a baseline hemoglobin below 120 g l(-1). Hence, the renoprotective properties of losartan were maintained despite a significant lowering of the hemoglobin concentration"

Elasticity Indices of Large and Small Arteries in Relation to the Metabolic Syndrome in Chinese - Am J Hypertens. 2008 Jan 10 - "The metabolic syndrome is indeed a risk factor for reduced arterial elasticity"

Blood Pressure and Risk of Cardiovascular Disease in Chinese Men and Women - Am J Hypertens. 2008 Jan 10 - "Our results indicate that there is a strong, linear, and independent relationship between BP levels and the risk of CVD in Chinese adults. Systolic BP is a stronger predictor of CVD risk compared to diastolic BP"

Daidzein-rich isoflavone aglycones are potentially effective in reducing hot flashes in menopausal women - Menopause. 2007 Jul 18 - "DRI supplementation may be an effective and acceptable alternative to hormone treatment for menopausal hot flashes"

The Association Between Statins and Cancer Incidence in a Veterans Population - J Natl Cancer Inst. 2008 Jan 8 - "After multivariable adjustment, a statistically significantly decreased risk of all cancers was also associated with increasing statin use"

Coffee, tea, caffeine and risk of breast cancer: A 22-year follow-up - Int J Cancer. 2008 - "our results suggested a weak inverse association between caffeine-containing beverages and risk of postmenopausal breast cancer"

Lycopene inhibits disease progression in patients with benign prostate hyperplasia - J Nutr. 2008 Jan;138(1):49-53 - "Whereas progression of prostate enlargement occurred in the placebo group as assessed by trans-rectal ultrasonography (P < 0.05) and digital rectal examination (P < 0.01), the prostate did not enlarge in the lycopene group. Symptoms of the disease, as assessed via the International Prostate Symptom Score questionnaire, were improved in both groups with a significantly greater effect in men taking lycopene supplements" - See Jarrow Lyco-Sorb at Amazon.com.

Health Focus (Green Tea):

• See green tea extract at Amazon.com.
• Chemical In Red Wine, Fruits And Vegetables Counters Unhealthy Effects Of High-fat Foods - Science Daily, 1/2/08 - "consuming polyphenols (natural compounds in red wine, fruits, and vegetables) simultaneously with high-fat foods may reduce health risks associated with these foods"
• Green tea may cut prostate cancer risk - USATODAY.com, 12/20/07 - "those who drank five or more cups of green tea a day reduced their risk of having progressive prostate cancer by half, compared with those who drank a cup or less"
• Green Tea May Protect Brain Cells Against Parkinson's Disease - Science Daily, 12/13/07 - "green tea polyphenols protect dopamine neurons that increases with the amount consumed. They also show that this protective effect is mediated by inhibition of the ROS-NO pathway, a pathway that may contribute to cell death in Parkinson's"
• Green Tea Shown To Possess Antitumor Effect In Breast Cancer - Science Daily, 12/8/07 - "green tea has antitumor effect in breast cancer cells ... Dr. Maheshwari’s study observed that green tea can inhibit the invading capacity of these breast cancer cells and have also identified the mechanisms involved in death inducing and invasion inhibiting effects of green tea"
• Chemoprevention, Naturally: Findings On Plant-derived Cancer Medicines - Science Daily, 12/6/07 - "rats fed a diet containing Polyphenon E, a standardized green tea polyphenol preparation, are less than half as likely to develop colon cancer ... After 34 weeks, rats that received Polyphenon E developed 55 percent fewer tumors compared to the control rats that did not receive Polyphenon E. Moreover, the tumors were 45 percent smaller in rats treated with green tea extract"
• Citrus Juice, Vitamin C Give Staying Power To Green Tea Antioxidants - Science Daily, 11/13/07 - "catechins are relatively unstable in non-acidic environments, such as the intestines, and less than 20 percent of the total remains after digestion ... Ascorbic acid, or vitamin C, used to increase shelf life in ready-to-drink products, increased recovered levels of the two most abundant catechins by sixfold and 13-fold, respectively"
• Green Tea Proves A Powerful Medicine Against Severe Sepsis In the Lab - Science Daily, 11/8/07 - "Survival jumped from 53 percent in those who didn't receive the green tea substance to 82 percent in those who did. "Clinically, even if we could save five percent of patients, that would be huge," ... In this study, we saved 25 percent more animals with the green tea"
• Green tea may halve prostate cancer risk - Nutra USA, 10/12/07 - "Drinking five or more cups a day was associated with a 48 per cent reduction in advanced prostate cancer risk, compared to drinking less than one cup per day"
• Drinking Tea May Slow Bone Loss - WebMD, 10/8/07 - "A new study shows elderly women who drank tea had higher bone density in their hips and less bone loss than women who didn't drink tea ... Previous studies have suggested that phytochemicals in tea, such as flavonoids, may be responsible for the protective effect against bone loss due to their estrogen-like properties"
• Put the kettle on: Tea is steeped in health benefits - USATODAY.com, 10/7/07 - "Tea polyphenols, compounds with antioxidant activity, may protect against heart disease and a variety of cancers ... green and black tea, when substituted for drinking water, inhibits the growth of human prostate cancer cells implanted in mice ... compounds in green tea positively affect genes involved in cancer susceptibility and DNA repair"
• Are You Easily Distracted? Try Some Tea - US News and World Report, 10/8/07 - "the amino acid theanine, which is found in green, black, and oolong teas, causes a decrease in the brain's "alpha rhythms" when people perform complex attention tasks, causing them to pay closer attention. His ongoing research, funded by the food and beverage conglomerate Unilever, suggests that theanine and caffeine together improve performance more than either substance alone ... in mice, at least—tea's main antioxidant shows an ability to curb brain cell death and encourage neurons to repair themselves" - See theanine at Amazon.com.
• Soda Warning? High-fructose Corn Syrup Linked To Diabetes, New Study Suggests - Science Daily, 8/23/07 - "high-fructose corn syrup (HFCS) ... Chi-Tang Ho, Ph.D., conducted chemical tests among 11 different carbonated soft drinks containing HFCS. He found 'astonishingly high' levels of reactive carbonyls in those beverages. These undesirable and highly-reactive compounds associated with "unbound" fructose and glucose molecules are believed to cause tissue damage ... Ho estimates that a single can of soda contains about five times the concentration of reactive carbonyls than the concentration found in the blood of an adult person with diabetes ... adding epigallocatechin gallate (EGCG), a compound in tea, significantly reduced the levels of reactive carbonyl species in a dose-dependent manner when added to the carbonated soft drinks studied. In some cases, the levels of reactive carbonyls were reduced by half"
• Green tea may cut oral cancer risk - study - Nutra USA, 8/22/07 - "women who consumed five or more cups of green tea per day had an associated risk reduction of 70 per cent, compared to women who consumed between one and two cups per day" - [Abstract]
• Green Tea Boosts Production Of Detox Enzymes, Rendering Cancerous Chemicals Harmless - Science Daily, 8/10/07 - "In a study of 42 people, the concentrate -- composed of chemicals known as green tea catechins in amounts equal to that found in 8-16 cups of green tea -- boosted production of the enzymes, which belong to the glutathione S-transferase (GST) family, by as much as 80 percent in some participants ... GST enzymes are believed to be crucial to the body's defense against cancer-causing chemicals and other toxins, according to the study's lead investigator, H.-H. Sherry Chow, Ph.D., a research associate professor at the University of Arizona. They modify the cancer-causing molecules that would otherwise damage cellular DNA, thus rendering them inert"
• Green Tea Holds Promise As New Treatment For Inflammatory Skin Diseases - Science Daily, 8/7/07 - "Green tea could hold promise as a new treatment for skin disorders such as psoriasis and dandruff ... Animal models treated with green tea also showed reduced levels of proliferating cell nuclear antigen, a gene expressed when skin cells multiply. In psoriasis, the gene is over-expressed and speeds production of skin cells"
• Green Tea May Protect Bladder From Becoming Inflamed - Science Daily, 5/20/07 - "catechins found in green tea protected both normal and cancerous bladder cells from inflammation when we exposed the cells to hydrogen peroxide ... these results indicate herbal supplements from green tea could be a treatment option for various bladder conditions that are caused by injury or inflammation"
• Green Tea Extract Protects Against Brain Damage In New Mouse Model Of HIV-related Dementia - Science Daily, 5/1/07 - "epigallocatechin-3-gallate (EGCG), the major antioxidant derived from green tea ... The green tea compound inhibited the ability of the cytokine to act with the HIV proteins to cause death and damage of the neurons"
• Green Tea vs. Rheumatoid Arthritis - WebMD, 4/30/07
• Green Tea Compound, EGCG, May Be A Therapy For People With Rheumatoid Arthritis - Science Daily, 4/29/07 - "the compound -- called epigallocatechin-3-gallate (EGCG) -- inhibited the production of several molecules in the immune system that contribute to inflammation and joint damage in people with rheumatoid arthritis"
• Tea 'could cut skin cancer risk' - BBC News, 4/19/07 - "Those who drank two or more cups a day had a 65% lower risk of developing squamous cell carcinoma"
• Green Tea And EGCG May Help Prevent Autoimmune Diseases - Science Daily, 4/19/07 - "The group treated with green tea had significantly fewer lymphocytes, Dr. Hsu says. Their blood also showed lower levels of autoantibodies, protein weapons produced when the immune system attacks itself, he says"
• Report: Green Tea - Natural Support For Healthy Weight Control - Life Extension Magazine, 4/07 - "Strong scientific evidence suggests that green tea confers critical cardiovascular benefits, may protect against a variety of deadly cancers, reduces the risk of diabetic complications, and may mitigate the effects of various autoimmune disorders ... If these broad-spectrum benefits were not reason enough for health-conscious adults to consider adding green tea to their daily supplement regimen, emerging research that confirms green tea’s effects in facilitating fat burning, weight management, and optimal body composition surely is"
• Green Tea And COX-2 Inhibitors Combine To Slow Growth Of Prostate Cancer - Science Daily, 3/1/07 - "In mice that were not treated with either substance, the tumor volume averaged 1,300 cubic millimeters, whereas mice given either the tea or celecoxib had tumors averaging 835 cubic millimeters and 650 cubic millimeters, respectively. Tumors taken from mice given both agents, however, measured on average a volume of 350 cubic millimeters"
• Get the diet scoop: 6 promising supplements, 6 to avoid - CNN, 2/16/07 - "promising ... Caffeine ... EGCG ... Chromium ... Conjugated Linoleic Acid (CLA) ... 5-HTP ... L-dopa or L-tyrosine"
• Cup Of Green Tea To Keep The Bacteria Away - Science Daily, 1/16/07 - "A cup of green tea contains up to 200 mg of catechins, whose biological activity has been mainly attributed to its antioxidant activity ... green tea catechins inhibit essential bacterial enzyme DNA gyrase, which is the target of several existing clinically used drugs"
• Milk Eliminates Cardiovascular Health Benefits Of Tea, Researchers Warn - Science Daily, 1/9/07 - "black tea significantly improves the ability of the arteries to relax and expand, but adding milk completely blunts the effect"
• More evidence for tea’s anticancer potential - Nutra USA, 12/21/06
• Tea Extracts Help Treat Damaged Skin In Cancer Patients - Science Daily, 11/1/06 - "tea extracts reduce the duration of radiation-induced skin damage by up to 10 days in patients who received radiation treatment"
• Confused about green tea? - MSNBC, 11/10/06
• Is Coffee or Tea Good for Your Liver? - Medscape, 10/2/06 - "The consumption of coffee and tea is associated with a reduced risk of CLD"
• Green Tea for Long Life? - WebMD, 9/12/06 - "Women who drink five or more 3.4-ounce cups of green tea every day cut their risk of heart disease by 31% compared with women who drink one or fewer 3.4-ounce cups. Men who drink this much green tea cut their heart disease risk by 22%"
• Tea linked to lower risk of bile stones and cancer - Nutra USA, 7/10/06
• Green Tea And The 'Asian Paradox' - Science Daily, 6/6/06 - "one theory is that the average 1.2 liters of green tea consumed daily by many people in Asia offers the anti-oxidant protective effects of the polyphenolic EGCG. EGCG may prevent LDL oxidation, which has been shown to play a key role in the pathophysiology of arteriosclerosis. EGCG also reduces the amount of platelet aggregation, regulates lipids, and promotes proliferation and migration of smooth muscle cells, which are all factors in reducing cardiovascular disease"
• Tea May Fight Ovarian, Breast Cancers - WebMD, 4/5/06 - "women who increase their consumption of kaempferol, a type of flavonoid, can lower their risk of ovarian cancer by nearly 40% ... women who consume a diet rich in other types of flavonoids - specifically, flavones, flavan-3-ols, and lignans -- can reduce their chance of developing breast cancer by 26% to 39%"
• Green tea may reduce, but black tea may increase breast cancer risk - Nutra USA, 2/21/06 - "Drinking five cups of green tea a day can reduce the risk of breast cancer by 22 per cent ... No such protective effect was found for black tea. Indeed, the results were contradictory: the cohort studies showed a small increased risk of breast cancer, while the case-control studies showed a small decreased risk"
• Green Tea May Do Wonders for the Brain - WebMD, 2/17/06 - "Those who reported drinking the most green tea were least likely to show cognitive impairment, based on their test scores ... Drinking at least two daily cups of green tea was tied to the lowest risk of cognitive impairment"
• Drinking Tea Associated With Lower Risk Of Ovarian Cancer - Science Daily, 1/3/06 - "We observed a 46 percent lower risk of ovarian cancer in women who drank two or more cups of tea per day compared with non-drinkers"
• Mayo Clinic Reports Some Chronic Leukemia Patients May Improve By Taking An Extract Of Green Tea - Science Daily, 12/13/05 - "In the small case study, the researchers report on four patients who appeared to have an improvement in the clinical state of their disease after starting over-the-counter products containing epigallocatechin gallate (EGCG), an extract of green tea. Three of the four patients met the standard criteria used to define a response treatment for clinical trials. These same investigators had previously shown that EGCG kills leukemia cells from patients with CLL in the test tube"
• Tea May Cut Ovarian Cancer Risk - WebMD, 12/12/05 - "Women who drank at least 2 cups of tea per day had a 46% lower risk of ovarian cancer compared with nontea drinkers; each additional cup of tea was associated with an 18% lower risk of ovarian cancer"
• Coffee and Tea Can Reduce Risk of Chronic Liver Disease - Doctor's Guide, 12/2/05 - "people at high risk for liver injury may be able to reduce their risk for developing chronic liver disease significantly by drinking more than two cups of coffee or tea daily. This preventative effect was only seen in people at higher risk for liver disease due to heavy alcohol intake, being overweight or having diabetes or iron overload"
• Does Green Tea Ingredient Protect Against Alzheimer’s? - Physician's Weekly, 11/28/05 - "The results suggest that an EGCG dietary supplement may help in preventing the disease in the future"
• Can Green Tea Protect Against Prostate Cancer? - Life Extension Magazine, 11/05 - "Thirty-two subjects received 200 mg of green tea catechins (50% EGCG) three times daily, while the other 30 men received a placebo. Biopsies were conducted at six months and one year later. Remarkably, only one man in the treatment group was diagnosed with prostate cancer, compared to nine men in the control group who developed the disease"
• Green Tea Ingredient Prevents Alzheimer's-like Brain Damage In Mice - Science Daily, 9/29/05
• Antioxidant in Green Tea May Fight Alzheimer's - WebMD, 9/20/05 - "high doses of the green tea ingredient -- known as epigallocatechin-3-gallate (EGCG) -- significantly reduced the formation of beta-amyloid proteins in the brains of mice that were altered to develop Alzheimer's disease"
• Green tea may benefit some more than others - MSNBC, 9/2/05 - "Since it is a powerful antioxidant, EGCG may help prevent both heart disease and cancer. It helps to stabilize highly reactive molecules known as free radicals that can damage blood vessels and increase the risk of heart disease, or alter the DNA in our genes, promoting cancerous changes. In addition, EGCG may protect against cancer development by increasing the self-destruction of cancer cells and by affecting enzymes and the signals between cells, slowing the growth and multiplication of cancer cells"
• FDA Rejects Green Tea Cancer Claims - WebMD, 7/5/05
• Green tea could fight autoimmune disorders - Nutra USA, 6/16/05
• Does a New Pill Contain the Fountain of Youth? - ABC News, 6/2/05 - "It is a combination of five plant ingredients. Two of them are pretty commonplace — green tea and turmeric, a spice used in Indian cooking"
• While On Trail Of Dioxin, Scientists Pinpoint Cancer Target Of Green Tea - Science Daily, 5/20/05 - "EGCG binds to HSP90 ... When the two bind, HSP90 no longer turns on the AH receptor, stopping the cascade of events that would lead to the activation of several harmful genes"
• Black Tea Has Both Positive and Negative Vascular Effects - Doctor's Guide, 5/18/05 - "The caffeine in black tea causes the stiffening of arteries ... The flavonoids in black tea produce the relaxation of the arteries"
• Mechanism for green tea's anti-cancer action revealed - Nutra USA, 5/17/05 - "It turns out that those researchers are trying to duplicate what green tea does naturally"
• Purified Green Tea Polyphenol Capsules Taken Daily Appear to Substantially Reduce Prostate Cancer in High Risk Patients - Doctor's Guide, 4/22/05 - "researchers reported a 90% decrease in the rate of prostate cancer in men who received 200 mg doses of the polyphenol capsules three times a day for 1 year"
• Black Tea, Green Tea Good for Diabetes - WebMD, 4/20/05 - "Black and green tea represent a potentially inexpensive, nontoxic, and, in fact, pleasurable [blood-sugar-lowering] agent"
• Tea May Help Prevent Diabetes And Cataracts - Science Daily, 4/19/05 - "At levels that would be equivalent to less than five cups of tea per day for a human, both teas significantly inhibited cataract formation relative to a control group which did not get tea, they say. The researchers found that both teas decreased glucose levels, which in turn affects other biochemical pathways that accelerate diabetic complications such as cataracts"
• Tea Ingredient Fights Leukemia - WebMD, 4/4/05 - "Tea extracts shut down leukemia cells but help normal cells fight cancer and infection"
• Green tea mechanism urges caution for pregnant women - Nutra USA, 3/17/05
• Component Of Green Tea Protects Injured Livers In Mice - Science Daily, 3/9/05
• Green tea 'may protect the heart' - BBC News, 2/28/05 - "a major chemical component of green tea known as epigallocatechin-3-gallate (EGCG) can reduce cell death after a heart attack or stroke ... EGCG also appears to speed up the recovery of heart cells"
• Green Tea Extract Shows Potential As An Anti-cancer Agent - Science Daily, 2/23/05 - "green tea extract interrupts a process that is crucial in allowing bladder cancer to become invasive and spread to other areas of the body" - See green tea extract at Amazon.com.
• Green Tea Helps Reduce Red in Rosacea - WebMD, 2/23/05 - "Women treated with the green tea extract cream had a 70% improvement in rosacea compared with women treated with a placebo"
• Green Tea's Record Against Cancer Grows - WebMD, 2/15/05 - "In effect, the green tea extract may keep the cancer cells confined and localized, where they are easier to treat and the prognosis is better ... you should drink four cups a day. Green tea supplements are also available, and at least one study has shown that you may actually get more powerful antioxidants from supplements than from drinking tea"
• Green Tea Extract Boosts Exercise Endurance 8-24%, Utilizing Fat As Energy Source - Science Daily, 1/31/05 - "over 10 weeks, endurance exercise performance was boosted up to 24% with 0.5% GTE [green tea extract] supplementation, and 8% with 0.2% by-weight addition to food ... We estimate that an athlete weighing 75 kilograms (165 pounds) would have to drink about four cups (0.8 liter) of green tea daily to match the effect in our experiments"
• Green Tea: The Next Performance Enhancer? - WebMD, 1/28/05 - "Ten weeks of green tea supplements plus strenuous exercise made mice swim longer and stronger than mice that swam their laps without performance enhancement ... The mice got stronger because the green tea made them burn fat more efficiently ... the amount of green tea eaten by the mice would work out to about 4 cups of green tea a day for a 165-pound human athlete"
• Green Tea Fights Fat - WebMD, 1/26/05 - "the first group drank a bottle of oolong tea fortified with green tea extract containing 690 milligrams of catechins, and the other group drank a bottle of oolong tea with 22 milligrams of catechins ... After three months, the study showed that the men who drank the green tea extract lost more weight (5.3 pounds vs. 2.9 pounds) and experienced a significantly greater decrease in BMI, waist size, and total body fat" - See iHerb or Vitacost green tea products.
• Harmful Fluoride Levels Found in Instant Tea - WebMD, 1/25/05
• Green tea for a healthy prostate? - MSNBC, 1/21/05 - "phytochemicals called polyphenols attack growth factors and proteins, interrupting processes that increase the size of tumors, thus preventing them from spreading to other parts of the body ... green tea in mice with an aggressive form of cancer can decrease the spread or metastasis of prostate cancer to liver, bone and other sites ... the phytochemicals in green tea could inhibit the early stages of prostate cancer development"
• Green Tea - Life Extension Magazine, 1/05 - "A powerful source of antioxidants, green tea may help to prevent cancer, protect the cardiovascular system, promote healthy blood sugar levels, and alleviate the neurological effects of aging"
• Green Tea - Delicious Living, 1/05
• Green Tea Capsules Loaded With Antioxidants - WebMD, 12/15/04 - "Green and black tea polyphenols have been extensively studied as cancer chemopreventive agents ... Green tea supplements produced the highest levels of antioxidants in the blood compared with liquid black or green tea"
• Green Tea Polyphenols Thwart Prostate Cancer Development At Multiple Levels - Science Daily, 12/15/04 - "The polyphenols present in green tea help prevent the spread of prostate cancer by targeting molecular pathways that shut down the proliferation and spread of tumor cells, as well as inhibiting the growth of tumor nurturing blood vessels"
• Capsules better delivery form for tea benefits than beverage - Nutra USA, 12/10/04 - "Our observations suggest that green tea extract supplements retain the beneficial effects of green and black tea and may be used in future chemoprevention studies to provide a large dose of tea polyphenols without the side effects of caffeine associated with green and black tea beverages"
• Green Tea May Stall Prostate Cancer Growth - WebMD, 12/1/04 - "the green tea antioxidant appeared to stall cell growth by decreasing production of several proteins that promote cell survival. In addition, it reduced the production of proteins that are known to be associated with the spread of cancer cells ... the study also suggests that the antioxidant in green tea appeared to starve prostate cancer tumor cells by inhibiting the formation of blood vessels, thereby suppressing the flow of nutrients to the cancerous cells" - See iHerb or Vitacost green tea products.
• Black, Green Tea May Slow Alzheimer's Disease - WebMD, 10/27/04
• Tea Drinkers Reap Blood Pressure Benefits - WebMD, 7/26/04 - "Those who drank at least a half-cup of moderate strength green or oolong tea per day for a year had a 46% lower risk of developing hypertension than those who didn't drink tea" - See iHerb or Vitacost green tea products.
• Green Tea Protects Against Cervical Cancer - Healthwell Exchange Daily News, 7/1/04
• Tea Slows Prostate Cancer - WebMD, 4/20/04
• Tea polyphenols to combat prostate cancer - Nutra USA, 4/20/04
• Green tea action on leukaemia - Nutra USA, 4/1/04 - "The active component in green tea, epigallocatechin-3-gallate (EGCG), already shown to fight several types of cancer, also appears to kill cells of the most common form of leukaemia"
• Sleep easy with green tea - Nutra USA, 3/16/04
• Green Tea's Cancer-Fighting Target Found - WebMD, 3/15/04 - "the antioxidant, known as EGCG, binds to a protein found on tumor cells and dramatically slows their growth ... the antioxidant required to produce these anticancer effects was equivalent to those found in the body after drinking only two to three cups of green tea"
• Green Tea Boosts Metabolism Without Increasing Heart Rate - Clinical Psychiatry News, 3/04 - "Patients took two 375-mg capsules twice daily, for a total daily epigallocatechin gallate dose of 270 mg ... By week 12, body weight decreased by a mean of 4.6% and waist circumference by 4.48%"
• Does tea really fight cancer? - MSNBC, 11/21/03 - "A new study of the potential link of green tea consumption with lower risk of breast cancer does suggest a protective benefit. Asian-American women who averaged at least three six-ounce cups of green tea per week were about half as likely to develop breast cancer as those who drank none ... One of the strengths of this study is that researchers statistically adjusted for the effects of many other influences on breast cancer risk"
• Hot Cocoa May Prevent Heart Disease - WebMD, 11/6/03 - "Hot cocoa has more disease-fighting antioxidants than tea or red wine ... black tea, green tea, red wine, and cocoa are "major" sources of antioxidants called phenols and flavonoids -- antioxidant chemicals found naturally in foods that can help prevent chronic diseases such as heart disease and cancer" - Yeah, but what about the sugar and calories.  See iHerb or Vitacost green tea products.
• Some Herbs May Fight Cancer - WebMD, 10/28/03
• Research Finds Tumor Preventive Qualities, Damage Reversal, In Green Tea - Intelihealth, 10/29/03 - "EGCG (epigallocatchin-3-gallate) is the most abundant and active chemopreventive agent in green tea, and has been associated with reduced risk of breast, pancreatic, colon, esophageal and lung cancers in humans ... At the same time, we see the value of green tea polyphenols in reducing excretion of 8-OHdG. All of this is good news for the prevention and early detection of liver cancer" - See iHerb or Vitacost green tea products.
• Tea Good for Heart Disease, Cancer - WebMD, 10/1/03
• Is Decaf Tea Less Protective? - Dr. Weil, 9/30/03
• Green Tea Lotion May Prevent Skin Cancer - WebMD, 9/8/03 - "a protein called JNK-2 appears to be directly related to the development of skin cancer and that this protein can be block blocked by the application of polyphenols. After the skin is exposed to UV light, levels of this protein rise and remain high ... green tea polyphenols reduce levels of JNK-2 in the skin and block the reaction that causes tumors to form ... a person would have to drink as many as ten cups of green tea a day in order to build up enough polyphenol molecules in the skin to produce any benefit"
• Enriched Green Tea Extract Lowers Cholesterol - New Hope Natural Media, 8/14/03
• Tea Extract Can Lower Cholesterol - WebMD, 6/23/03
• Green Tea Boosts Antimicrobial Properties Of Toothpaste - Intelihealth, 5/21/03 - "green tea extracts (GTE) and polyphenol (PP) have an adverse effect on bacteria that cause strep throat, dental caries, and other infections"
• Tea Fights Bad Breath, Mouth Bacteria - WebMD, 5/20/03
• Green Tea Gives Skin Healthy Glow - HealthDay, 5/15/03 - "Green tea contains compounds called polyphenols, which help eliminate free radicals. These free radicals can cause cancer by altering DNA. Polyphenols also protect healthy cells while promoting the death of cancer cells ... Cells that migrate toward the surface of the skin normally live about 28 days, and by day 20 they basically sit on the upper layer of the skin getting ready to die. But EGCG reactivates them ... EGCG may offer potential benefits for skin conditions including psoriasis, rosacea, wrinkles and wounds"
• Steeped In Health - Time, 5/5/05 - "The researchers found that drinking 20 oz. of tea every day for at least two weeks doubled or tripled the immune system's output of an infection-fighting substance called interferon gamma. The coffee drinkers, by contrast, registered no difference in interferon-gamma production. Apparently the body metabolizes the tea into molecules that mimic the surface proteins of bacteria, jump-starting the immune system so that when real bugs show up, they can more easily be dispatched ... Green tea has more of the chemically simpler antioxidants called catechins, whereas black tea contains more complex antioxidants called theaflavins and thearubigins"
• Health Benefit of Tea: Add Immune Boost That Helps Fight Germs - WebMD, 4/21/03
• Green Tea Supplement May Delay Diabetes - WebMD, 4/16/03
• A Derivative Of The Green Tea Leaf May Help With Metabolic Syndrome X, A Potentially Deadly Disorder - Intelihealth, 4/10/03 - "A new weapon might eventually be added to the arsenal: consumption of Tegreen, a tea polyphenols product containing in excess of 65 percent tea catechins, derived from the green tea leaf ... oral administration of Tegreen is capable of improving glucose and lipid metabolisms in an obese rat model induced by a high-calorie diet ... Tegreen intervention can significantly decrease visceral fat depot and increase the insulin's sensitivity, presumably touching one of the pathological root causes of this potentially deadly syndrome" - See iHerb or Vitacost green tea products.
• Green Tea Doesn't Help Prostate Cancer - WebMD, 3/5/03
• Herb Mix Nixes Prostate Cancer in Lab - WebMD, 12/13/02 - "A number of recent studies point to COX-2 as an important factor in cancer-cell growth. In the Columbia studies, Zyflamend decreased COX-2 activity about as well as a potent COX-2-inhibiting drug ... The herbal mix is called Zyflamend, from New Chapter Inc., and has 10 herbs: holy basil, turmeric, ginger, green tea, rosemary, hu zhang, Chinese goldthread, barberry, oregano, and Scutellaria biacalensis"
• More Good News on Tea - WebMD, 9/27/02 - "The latest studies suggest tea might lower cholesterol, improve heart health, prevent rectal cancer in women, and reduce cell damage in smokers"
• Green Tea, Allergy Fighter? - WebMD, 9/24/02
• Green Tea May Fight Allergies - Intelihealth, 9/19/02 - "Researchers in Japan identified a compound in green tea that, in laboratory tests, blocks a key cell receptor involved in producing an allergic response ... Researchers in Japan identified a compound in green tea that, in laboratory tests, blocks a key cell receptor involved in producing an allergic response ... Although similar compounds in green tea have previously been shown to be anti-allergenic, this particular compound appears to be the most potent"
• Green Tea Cancer Benefits Detailed - USA Today, 7/9/02 - "polyphenols in green tea help eliminate free radicals ... Hsu discovered the polyphenols actually separate healthy cells containing the P-57 protein from cancer cells, which lack the protein. While the healthy cells are sent to safety, the polyphenols attack the cancer cells ... The polyphenols go after the cancer cells' mitochondria, the main energy source in cells. The destruction of the mitochondria weakens the cancer cells, and eventually leads to their death" - See iHerb or Vitacost green tea products.
• Long-Time Tea Drinking Builds Strong Bones - WebMD, 5/14/02
• Habitual Tea Drinking Improves Adult Bone Mineral Density - Doctor's Guide, 5/13/02
• Tea May Strengthen Bones - Intelihealth, 5/13/02
• Drinking Tea May Help Prevent Heart Attacks - Doctor's Guide, 5/9/02 - "Drinking more tea and increasing flavonoid intake may help primary prevention of ischaemic heart disease ... The intake of the dietary flavonoids quercetin, kaempferol and myricetin was significantly associated inversely with fatal myocardial infarction only in upper tertiles of intake"
• Tea Prolongs Survival After Heart Attack - WebMD, 5/6/02 - "Researchers say the findings add to a growing notion that the antioxidant-rich flavonoids found in black and green teas prevent heart disease. But this is the first study to suggest that drinking tea can actually protect the heart after damage has already occurred"
• Tea Lowers Risk of Ischemic Heart Disease - Medscape, 4/29/02
• Tea Drinking Good for the Heart - WebMD, 4/25/02
• Green Tea May Aid Liver Disease Patients - WebMD, 4/23/02 - "survival rate was bumped up to 77% for rats that received a fatty liver bathed in green tea extract"
• A Green Tea Extract Could Help Alleviate Shortage Of Livers Available For Transplant - Intelihealth, 4/22/02 - "Polyphenols are efficient free radical and single oxygen scavengers, and green tea extracts inhibit lipid peroxidation in experimental animals and humans. Green tea contains high levels of polyphenols including catechin, epicatechin, gallocatechin, epigallocatechin, epicatechin gallate and gallocatechin gallate. Considerable epidemiological and experimental evidence shows beneficial effects of green tea extract in reducing the risk of heart disease and cancer, most likely due to the antioxidant property of polyphenols"
• Green Tea Protects Against Parkinson's - WebMD, 4/16/02 - "In a mouse study, the researchers found that polyphenol blocks MPP+ -- a substance that is known to kill brain cells and cause Parkinson's in mice -- from entering these brain cells ... if you want to try it and don't care for the taste of green tea, concentrated polyphenol capsules are available"
• Common Foods Help Prevent Cancer - WebMD, 4/10/02 - "found that regular green tea drinking cut cancer risk in half ... men who ate more than two servings of tomato sauce per week had a 23% lower risk of prostate cancer than men who ate less than one serving a week"
• How to Stay Healthy in 2002, Green Tea - Time Magazine, 1/21/02
• Green tea polyphenols inhibit prostate cancer in mouse model - Life Extension Magazine, 12/01 - "According to study findings published in the August 28, 2001 issue of the Proceedings of the National Academy of Sciences [PNAS 2001 Aug;98(18):10350-10355], green tea polyphenols—the equivalent found in about six cups of green tea per day in humans—helped to significantly reduce the risk of prostate cancer in a mouse model"
• Green Tea, Glycine May Slow Tumor Growth - WebMD, 11/2/01 - "polyphenols reduced the level of Bcl-XL protein in prostate cancer cell lines. Bcl-XL has been shown to protect cancer cells from death -- known scientifically as apoptosis ... The higher the concentration [of polyphenols] the more apoptosis"
• question regarding your new cholesterol-lowering supplement, Policosanol - Life Extension Magazine, 11/01 - "Green tea also has been shown to elevate levels of HDL while lowering serum triglyceride levels"
• Does Green Tea Aid in Cancer Prevention? - Life Extension Magazine, 10/01
• Tea leaves may foretell health benefits - CNN, 7/10/01
• Tea Time? Black Tea May Help Heart - WebMD, 7/9/01 - "drinking black tea may improve functioning of cells lining blood vessels in the heart and elsewhere-- known as endothelial cells -- which help regulate flow of blood. Abnormal functioning of these endothelial cells has been shown to be a key step on the path to the artery hardening disease atherosclerosis, which causes coronary artery disease"
• Tea Up Before Heading Out, Researchers Find Green Tea May Prevent Skin Cancer - WebMD, 12/22/00
• Research suggests tea might be good for the heart - CNN, 11/14/00
• Tea May Be Heart-Healthy - Intelihealth, 11/14/00
• Research Reveals Soy, Niacin, and Tea Offer Protection From Heart Attack and Stroke - WebMD, 11/13/00
• Green Tea Could Be Good for Your Skin, Study Finds - WebMD, 8/17/00
• Green tea may help prevent skin cancer - CNN, 8/15/00
• Tea's reputation as a healthy brew increasing - CNN, 6/19/00
• There's Something to Be Said for Having 'Tea Bones' - WebMD, 4/14/00
• Researchers Suggest Daily Tea May Fortify Bones Of Elderly Women - Intelihealth, 4/7/00
• Green Tea Could Promote Weight Loss - Nutrition Science News, 4/00
• Green Tea Lowers Cholesterol - Nutrition Science News, 10/99
• Part I: Anti-carcinogenic properties of green tea - Life Extension Magazine, 6/99
• Part II: Cardio-protective properties of green tea - Life Extension Magazine, 6/99
• Tea: Steeped in Anticancer Properties - Nutrition Science News, 3/99
• Study: Tea may be key to protecting against some cancers - CNN, 9/15/98
• The right cup of tea for good health? - CNN, 9/11/97

Green Tea Abstracts:

• The combination of epigallocatechin gallate and curcumin suppresses ERalpha-breast cancer cell growth in vitro and in vivo - Int J Cancer. 2007 Dec 20 - "Tumor volume in the EGCG + curcumin treated mice decreased 49% compared to vehicle control mice (p < 0.05), which correlated with a 78 +/- 6% decrease in levels of VEGFR-1 protein expression in the tumors. Curcumin treatment significantly decreased tumor protein levels of EGFR and Akt, however the expression of these proteins was not further decreased following combination treatment. Therefore, these results demonstrate that the combination of EGCG and curcumin is efficacious in both in vitro and in vivo models of ERalpha- breast cancer and that regulation of VEGFR-1 may play a key role in this effect"
• Effects of green tea on insulin sensitivity, lipid profile and expression of PPARalpha and PPARgamma and their target genes in obese dogs - Br J Nutr. 2007 Dec 6;:1-9 - "At 12 weeks in the green tea group, mean insulin sensitivity index was 60 (sem 11) % higher (P < 0.05) and TAG concentration 50 (sem 10) % lower (P < 0.001), than baseline ... These findings show that nutritional doses of green tea extract may improve insulin sensitivity and lipid profile and alter the expression of genes involved in glucose and lipid homeostasis"
• Prevention of hypertension, cardiovascular damage and endothelial dysfunction with green tea extracts - Am J Hypertens. 2007 Dec;20(12):1321-8 - "green tea extract (GTE) ... The GTE prevented hypertension and target organ damage induced by a high Ang II dose, likely by prevention or scavenging of superoxide anion generation"
• Chronic green tea extract supplementation reduces hemodialysis-enhanced production of hydrogen peroxide and hypochlorous acid, atherosclerotic factors, and proinflammatory cytokines - Am J Clin Nutr. 2007 Nov;86(5):1539-47 - "Catechins reduce hemodialysis-induced production of hydrogen peroxide and hypochlorous acid, atherosclerotic disease risk factors, and proinflammation"
• Tea drinking is associated with benefits on bone density in older women - Am J Clin Nutr. 2007 Oct;86(4):1243-1247 - "In the cross-sectional analysis, total hip aBMD was 2.8% greater in tea drinkers (x: 806; 95% CI: 797, 815 mg/cm(2)) than in non-tea drinkers (784; 764, 803 mg/cm(2)) (P < 0.05). In the prospective analysis over 4 y, tea drinkers lost an average of 1.6% of their total hip aBMD (-32; -45, -19 mg/cm(2)), but non-tea drinkers lost 4.0%"
• Green Tea Consumption and Prostate Cancer Risk in Japanese Men: A Prospective Study - Am J Epidemiol. 2007 Sep 29 - "The multivariate relative risk was 0.52 (95% confidence interval: 0.28, 0.96) for men drinking 5 or more cups/day compared with less than 1 cup/day (p(trend) = 0.01). Green tea may be associated with a decreased risk of advanced prostate cancer"
• Can EGCG Reduce Abdominal Fat in Obese Subjects? - J Am Coll Nutr. 2007 Aug;26(4):396S-402S - "heart rate (HR) ... Moderate consumption of EGCG can improve the health status of overweight individuals undergoing regular exercise by reducing HR and plasma glucose concentrations. Loss of body fat, however, may require a higher intake of EGCG, other catechins or addition of metabolic stimulants"
• The effects of epigallocatechin-3-gallate on thermogenesis and fat oxidation in obese men: a pilot study - J Am Coll Nutr. 2007 Aug;26(4):389S-95S - "These findings suggest that EGCG alone has the potential to increase fat oxidation in men and may thereby contribute to the anti-obesity effects of green tea"
• Synergic Anticandidal Effect of Epigallocatechin-O-gallate Combined with Amphotericin B in a Murine Model of Disseminated Candidiasis and Its Anticandidal Mechanism - Biol Pharm Bull. 2007 Sep;30(9):1693-6
• A Prospective Study of Green Tea Consumption and Oral Cancer Incidence in Japan - Ann Epidemiol. 2007 Jun 30 - "For women, the HRs of oral cancer for green tea consumption of 1-2, 3-4, and 5 or more cups per day were 0.51 (95% CI: 0.10-2.68), 0.60 (95% CI: 0.17-2.10), and 0.31 (95% CI: 0.09-1.07), respectively, compared with those who drank less than one cup per day (p for trend, 0.08). For men, no such trends were observed"
• Inhibition Of Tumorigenesis in Apc(Min/+) Mice by a Combination of (-)-Epigallocatechin-3-gallate and Fish Oil - J Agric Food Chem. 2007 Aug 16 - "The effect of a combination of (-)-epigallocatechin-3-gallate (EGCG) with fish oil on intestinal tumorigenesis in Apc (Min/+) mice fed a high-fat diet was investigated in the present study. The combined treatment of EGCG and fish oil for 9 weeks reduced the tumor number by 53% as compared to controls while neither agent alone had a significant effect. Apoptosis was significantly increased in all treatment groups"
• Green tea selectively targets initial stages of intestinal carcinogenesis in the AOM-ApcMin mouse model - Carcinogenesis. 2007 Jul 17 - "green tea specifically targets initial stages of colon carcinogenesis; the time of administration of green tea is pivotal for effective chemoprevention. Beverage levels of GT are not likely to inhibit the progress of any large adenomas or adenocarcinomas existing prior to the tea administration"
• Protective Effect of (-)-Epigallocatechin Gallate against Advanced Glycation Endproducts-Induced Injury in Neuronal Cells - Biol Pharm Bull. 2007 Aug;30(8):1369-73 - "Advanced glycation endproducts (AGEs) are believed to be secondary factors in the selective neuronal injury associated with several neurodegenerative disorders. In this study, we investigated the protective effects of (-)-epigallocatechin gallate (EGCG), a major monomer of green tea polyphenols, against AGEs-induced damage in neuron cells. The results showed that EGCG treatment protected against glyceraldehyde-derived AGE-induced neurotoxicity"
• Intakes of coffee, tea, milk, soda and juice and renal cell cancer in a pooled analysis of 13 prospective studies - Int J Cancer. 2007 Jun 21 - "Coffee consumption was associated with a modestly lower risk of renal cell cancer (pooled multivariate RR for 3 or more 8 oz (237 ml) cups/day versus less than one 8 oz (237 ml) cup/day = 0.84 ... Tea consumption was also inversely associated with renal cell cancer risk (pooled multivariate RR for 1 or more 8 oz (237 ml) cups/day versus nondrinkers = 0.85"
• Randomized controlled trial for an effect of green tea-extract powder supplementation on glucose abnormalities - Eur J Clin Nutr. 2007 Jun 6 - "consumed a packet of green tea-extract powder containing 544 mg polyphenols (456 mg catechins) daily ... A significant reduction in hemoglobin A1c level and a borderline significant reduction in diastolic blood pressure were associated with the intervention"
• Prospective cohort study of green tea consumption and colorectal cancer risk in women - Cancer Epidemiol Biomarkers Prev. 2007 Jun;16(6):1219-23 - "The multivariate relative risk of CRC was 0.63 (95% confidence interval, 0.45-0.88) for women who reported drinking green tea regularly at baseline compared with nonregular tea drinkers" - I read that as a 37% reduction in risk. - Ben
• Acute EGCG Supplementation Reverses Endothelial Dysfunction in Patients with Coronary Artery Disease - J Am Coll Nutr. 2007 Apr;26(2):95-102 - "epigallocatechin gallate (EGCG), a major catechin in tea ... EGCG acutely improves endothelial function in humans with coronary artery disease, and may account for a portion of the beneficial effects of flavonoid-rich food on endothelial function"
• Tea and lycopene protect against prostate cancer - Asia Pac J Clin Nutr. 2007;16 Suppl:453-7 - "The protective effect of green tea was significant (odds ratio 0.14, 95% CI: 0.06-0.35) for the highest quartile relative to the lowest after adjusting for total vegetables and fruits intakes and other potential confounding factors. Intakes of vegetables and fruits rich in lycopene were also inversely associated with prostate cancer risk (odds ratio 0.18 ... habitual drinking tea and intakes of vegetables and fruits rich in lycopene could lead to a reduced risk of prostate cancer in Chinese men. Together they have a stronger preventive effect than either component taken separately"
• Tea consumption and basal cell and squamous cell skin cancer: Results of a case-control study - J Am Acad Dermatol. 2007 Jan 26 - "Our findings support the existence of an inverse association between tea consumption and skin carcinogenesis"
• Green Tea Consumption and Mortality Due to Cardiovascular Disease, Cancer, and All Causes in Japan: The Ohsaki Study - JAMA, 9/13/06 - "Green tea consumption is associated with reduced mortality due to all causes and due to cardiovascular disease but not with reduced mortality due to cancer"
• Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya Project 1 - Am J Clin Nutr. 2006 Feb;83(2):355-61 - "A higher consumption of green tea is associated with a lower prevalence of cognitive impairment in humans"
• Tea consumption and ovarian cancer risk in a population-based cohort - Arch Intern Med. 2005 Dec 26;165(22):2683-6 - "Each additional cup of tea per day was associated with an 18% lower risk of ovarian cancer"
• Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men - Am J Clin Nutr. 2005 Jan;81(1):122-9 - "Body weight, BMI, waist circumference, body fat mass, and subcutaneous fat area were significantly lower in the green tea extract group than in the control group"
• Plasma-kinetic characteristics of purified and isolated green tea catechin epigallocatechin gallate (EGCG) after 10 days repeated dosing in healthy volunteers - Int J Vitam Nutr Res. 2004 Jul;74(4):269-78 - "Ten days' repeated administration of oral doses of EGCG of up to 800 mg per day were found to be safe and very well tolerated"
• Bioavailability and antioxidant activity of tea flavanols after consumption of green tea, black tea, or a green tea extract supplement - Am J Clin Nutr. 2004 Dec;80(6):1558-64 - "Flavanol absorption was enhanced when tea polyphenols were administered as a green tea supplement in capsule form and led to a small but significant increase in plasma antioxidant activity compared with when tea polyphenols were consumed as black tea or green tea. All 3 interventions provided similar amounts of (-)-epigallocatechin-3-gallate"
• Effects of green tea intake on the development of coronary artery disease - Circ J. 2004 Jul;68(7):665-70 - "the more green tea patients consume, the less likely they are to have CAD"
• The Protective Effect of Habitual Tea Consumption on Hypertension - Arch Intern Med. 2004;164:1534-1540
• VEGF Receptor Phosphorylation Status and Apoptosis is Modulated by a Green Tea Component, Epigallocatechin-3-gallate (EGCG) in B cell Chronic Lymphocytic Leukemia - Blood. 2004 Mar 2
• Antioxidant effects of tea: evidence from human clinical trials - J Nutr. 2003 Oct;133(10):3285S-92S - "tea flavonoids are potent antioxidants that are absorbed from the gut after consumption. Tea consumption consistently leads to a significant increase in the antioxidant capacity of the blood. Beneficial effects of increased antioxidant capacity in the body may be the reduction of oxidative damage to important biomolecules. The scientific support is strongest for the protection of DNA from oxidative damage after black or green tea consumption"
• Mechanisms of cancer prevention by tea constituents - J Nutr. 2003 Oct;133(10):3262S-7S - "Consumption of tea (Camellia sinensis) has been suggested to prevent cancer, heart disease and other diseases. Animal studies have shown that tea and tea constituents inhibit carcinogenesis of the skin, lung, oral cavity, esophagus, stomach, liver, prostate and other organs. In some studies, the inhibition correlated with an increase in tumor cell apoptosis and a decrease in cell proliferation"
• Tea Intake Is Inversely Related to Blood Pressure in Older Women - J Nutr. 2003 Sep;133(9):2883-2886 - "Tea is rich in polyphenols, which have activities consistent with blood pressure-lowering potential ... Higher tea intake and higher 4-O-methylgallic acid excretion were associated with significantly lower systolic (P = 0.002 and P = 0.040, respectively) and diastolic (P = 0.027 and P < 0.001, respectively) blood pressures. A 250 mL/d (1 cup) increase in tea intake was associated with a 2.2 (0.8, 3.6) mm Hg lower systolic blood pressure and a 0.9 (0.1, 1.7) mm Hg lower diastolic blood pressure" - See iHerb or Vitacost green tea products.
• Cholesterol-Lowering Effect of a Theaflavin-Enriched Green Tea Extract - Arch Intern Med. 2003;163:1448-1453 - "randomly assigned to receive a daily capsule containing theaflavin-enriched green tea extract (375 mg) or placebo for 12 weeks ... After 12 weeks, the mean +/- SEM changes from baseline in total cholesterol, LDL-C, HDL-C, and triglyceride levels were -11.3% +/- 0.9% (P = .01), -16.4% +/- 1.1% (P = .01), 2.3% +/- 2.1% (P = .27), and 2.6% +/- 3.5% (P = .47), respectively"

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