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Home > Anti-aging Research > Carotenoids.

Carotenoids

Specific Recommendations:

News & Research:

  • Astaxanthin compound found to switch on the FOX03 'Longevity Gene' in mice - Science Daily, 3/28/17 -"The Astaxanthin compound CDX-085 (developed by Cardax) showed the ability to significantly increase the expression of the FOXO3 gene, which plays a proven role in longevity ... We found a nearly 90% increase in the activation of the FOXO3 "Longevity Gene" in the mice fed the higher dose of the Astaxanthin compound CDX-085" - See BioAstin at Amazon.com
  • Plant compounds may boost brain function in older adults, study says - Science Daily, 11/29/16 - "People get these compounds, known as carotenoids, from their diets, and two of them -- lutein and zeaxanthin -- have been shown in previous research to bolster eye and cognitive health in older adults ... In this study, participants with lower levels of lutein and zeaxanthin had to use more brain power and relied more heavily on different parts of the brain in order to remember the word pairings they were taught. People with higher levels, on the other hand, were able to minimize the amount of brain activity necessary to complete the task. In other words, they were more "neurally efficient."" - See zeaxanthin lutein at Amazon.com.
  • Clinical Study Shows AstaReal(R) Astaxanthin Effective in Reducing both Mental and Physical Fatigue - yonhapnews.co.kr, 11/7/16 - "AstaReal® astaxanthin significantly reduced perceived symptoms of mental and physical fatigue compared to the placebo. These included improvements in clarity of thinking, concentration, motivation, and mood. Irritation and feeling of body heaviness were reduced. In the calculation test, an increase in errors observed in the placebo during the second half of the test was almost eliminated in the astaxanthin group. Supplementation with astaxanthin also significantly reduced salivary cortisol, a biomarker for stress" - [Nutra USA] - See astaxanthin at Amazon.com.
  • Beta-cryptoxanthin, a carotenoid, inhibits nicotine-linked lung cancer development in mice - Science Daily, 11/1/16 - "The team calculated that these doses are equivalent to approximately 0.087 and 0.87 milligrams of daily BCX intake in humans (eating a tangerine or cup of sweet red peppers per day, for example) ... At the end of the experimental period, mice fed BCX developed on average 50 to 60 percent fewer tumors than mice not fed BCX ... The team's findings corroborate human epidemiological studies that have found an association between higher BCX intake and lower risk of lung cancer in current smokers from North America and Asian countries"
  • Benefits of taking the natural pigment astaxanthin - Science Daily, 2/22/16 - "ASX has a powerful antioxidant effect, and it holds promise as a next-generation natural supplement. ASX is capable of penetrating the blood-brain barrier, entering the brain, where it acts directly on nerve cells. ASX is also known to have a neuroprotective effect in neurological animal disease model ... A research group led by University of Tsukuba Faculty of Health and Sport Sciences Professor Hideaki Soya and Professor Randeep Rakwal has investigated the effect on hippocampal function of the naturally-derived pigment ASX, which is believed to have the most powerful antioxidant activity among carotenoids. Their results showed for the first time that giving ASX to mice for four weeks promoted neurogenesis in the hippocampus in a concentration-dependent manner, and elevated the learning and memory capacity of the hippocampus" - See astaxanthin at Amazon.com.
  • Vitamin A is for anti-aging, at least when it comes to vision - The Washington Post, 7/14/15 - "There are essentially two forms of the vitamin: retinoids, or preformed vitamin A, found in animal products and carotenoids; and provitamin A, dark-colored plant pigments that are converted to vitamin A in the body ... Food sources: Liver, shrimp, salmon, sardines, halibut, cod, beef, lamb, eggs, whole milk, whole yogurt ... Carotenoids are antioxidants that prevent and repair cellular damage and aging and reduce inflammation in the eyes and elsewhere in the body. The carotenoids lutein and zeaxanthin are found in the retina of the human eye and have been shown to help prevent age-related macular degeneration. Carotenoids also may reduce the risk for cancer ... Food sources: Spinach, kale, Swiss chard, other dark leafy greens, carrots, sweet potatoes, winter squash, apricots and cantaloupe ... Not only does vitamin A help with eyesight by producing the pigments of the retina and preventing macular degeneration, but it also helps create and maintain healthy skin (hence the popularity of topical Retin-A skincare products) ... Avoid excessively bright light from harsh interior lighting or strong sunlight. Most offices are twice as bright as they need to be. Use low-intensity light bulbs and floor lamps instead of fluorescent lighting" - See Puritan's Pride Lutein 20 mg with Zeaxanthin-120 Softgels at Amazon.com.
  • Lycopene may ward off kidney cancer in older women - Science Daily, 3/2/15 - "after analyzing data from 96,196 women nationwide and in Detroit who enrolled in the Women's Health Initiative from 1993 to 1998 and were followed through July 2013 ... Compared with women who reported a lower intake of lycopene, those who ingested more had a 39 percent lower risk. No other micronutrient was significantly associated with the same risk" - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com.
  • Eat your fruits, vegetables for skin with sun-kissed glow - Science Daily, 8/27/14 - "Skin coloration can arise as a result of two distinct processes," explain the team leading the research: through tanning (melanisation) or the assimilation of fruit and vegetables (carotenoid ingestion) ... Results from both studies showed a clear preference for strong color values; 86% of the attendants to the first study voted for the high carotenoid version, while 78.5% of the participants to the second one opted for the high melanin variant ... in a third and final study, the team pitched 24 high carotenoid and high melanin faces against each other, asking attendants to choose the one deemed more appealing; results showed a 75.9% preference for carotenoid coloring over the melanin one" - See carotenoids at Amazon.com.
  • Fighting prostate cancer with tomato-rich diet - Science Daily, 8/27/14 - "the first study of its kind to develop a prostate cancer 'dietary index' which consists of dietary components -- selenium, calcium and foods rich in lycopene -- that have been linked to prostate cancer ... Men who had optimal intake of these three dietary components had a lower risk of prostate cancer ... Tomatoes and its products -- such as tomato juice and baked beans -- were shown to be most beneficial, with an 18 per cent reduction in risk found in men eating over 10 portions a week ... This is thought to be due to lycopene, an antioxidant which fights off toxins that can cause DNA and cell damage" - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com.
  • 'Tomato pill' improves function of blood vessels in patients with cardiovascular disease - Science Daily, 6/9/14 - "One component of the Mediterranean diet thought to play a role in reducing this risk is lycopene, a powerful antioxidant which is ten times more potent than vitamin E. Lycopene is found in tomatoes and other fruits, and its potency appears to be enhanced when it is consumed pureed, in ketchup or in the presence of olive oil ... Thirty-six cardiovascular disease patients and thirty-six healthy volunteers were given either Ateronon (an off-the-shelf supplement containing 7mg of lycopene) or a placebo treatment ... 7mg of oral lycopene supplementation improved and normalised endothelial function in the patients, but not in healthy volunteers. Lycopene improved the widening of the blood vessels by over a half (53%) compared to baseline in those taking the pill after correction for those who took the placebo" - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com.
  • Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration: the Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial - Medscape, 1/16/14 - "Serum levels of lutein at year 5 were lower in patients receiving lutein + zeaxanthin and beta carotene than in patients receiving lutein + zeaxanthin without beta carotene ... The study showed a protective effect of lutein + zeaxanthin on progression to advanced AMD, with omission of beta carotene" - Note:  I've been mentioning for years that taking large does of beta carotene can cause a deficiency of some of the over 600 carotenoids.  It doesn't mention the amount of beta carotene in this article.  I'm sticking with the broad array formulas of carotenoids.  See carotenoids at Amazon.com.
  • Lutein, Zeaxanthin, and Skin Health - Medscape, 6/7/13 - "Results from cell culture and animal studies showing that lutein and zeaxanthin exhibit positive skin health benefits have considerable merit and suggest an avenue by which these carotenoids may function. The results from one human study demonstrate that orally administered lutein and zeaxanthin can inhibit lipid peroxidation on the surface of the skin and help bolster the skin's photoprotective activity, potentially protecting the skin from exposure to light, particularly UV light. Since the typical diet of people in the United States is about 2 mg of lutein per day, due to the ingestion of foods such as green leafy vegetables that contain the highest levels of diet-derived lutein and zeaxanthin,[15] it may be considered advisable to increase the daily intake of lutein and zeaxanthin for optimal skin health and photoprotection"
  • Eating Bright-Colored Fruits and Vegetables May Prevent or Delay Amyotrophic Lateral Sclerosis - Science Daily, 1/29/13 - "Using data from five prospective groups: the National Institutes of Health (NIH)–AARP Diet and Health Study, the Cancer Prevention Study II-Nutrition Cohort, the Multiethnic Cohort, the Health Professionals Follow-up Study, and the Nurses’ Health Study, researchers investigated more than one million participants for the present study ... subjects with diets high in beta-carotene and lutein—found in dark green vegetables—had a lower risk ALS risk"
  • Antioxidants May Slow Age-Related Macular Degeneration - Medscape, 12/31/12 - "Oral antioxidant supplementation, including with lutein and zeaxanthin, was associated with some benefits in macular function and morphologic features among patients at high risk for progression to advanced age-related macular degeneration (AMD) ... This trial and several others indicate benefits to functional vision with lutein supplementation. What this trial has demonstrated over and above is the marginal slowing down of progression along the early AMD severity scale ... Participants in the supplement arm took a tablet twice daily to provide a daily dose of 12 mg lutein, 0.6 mg zeaxanthin, 15 mg d-α-tocopherol (vitamin E), 150 mg ascorbic acid (vitamin C), 20 mg zinc oxide, and 0.4 mg copper gluconate ... At 36 months, the difference in BCVA had increased to approximately 4.8 letters in favor of the supplement"
  • Cartenoids found to reduce hip fracture risk in lean men - Science Daily, 12/16/12 - "Elderly who are lean (BMI <20 kg/m2) are at higher risk of hip fracture compared to those with higher BMI ... researchers examined the association between dietary antioxidant carotenoids and hip fracture risk across a range of BMI in elderly Chinese men and women using data from the Singapore Chinese Health Study ... low BMI is a stronger risk factor for hip fracture risk among elderly men compared to women ... Also, in men, hip fracture risk decreased with increasing intakes of total vegetables and of total carotenoids, particularly β-carotene"
  • Women with higher carotenoid levels have reduced risk of breast cancer - Science Daily, 12/7/12 - "Carotenoids, which are micronutrients found in fruits and vegetables, have been found to have anticarcinogenic properties. Previous experimental studies have shown that carotenoids inhibit the tumor progression and reduce proliferation of estrogen receptor-positive (ER+) and estrogen receptor-negative (ER-) breast cancers ... Heather Eliassen, Channing Division of Network Medicine, Department of Medicine, Brigham & Women's Hospital and Harvard Medical School, and colleagues, conducted a pooled analysis of eight cohort studies, which gathered over 80% of the world's published prospective data on plasma or serum carotenoids and breast cancer ... The researchers found that in over 3,000 case subjects, there were statistically significantly inverse associations between circulating levels of individual and total carotenoids and breast cancer risk, with a stronger finding in ER- breast cancers"
  • Tomatoes May Lower Your Risk for Stroke - WebMD, 10/8/12 - "Men who had the highest levels of lycopene in their blood were 55% less likely to have a stroke, compared with men who had the lowest levels of the antioxidant in their blood ... The new study included slightly more than 1,000 men from Finland aged 46 to 65. Researchers measured the level of lycopene in their blood when the study began and followed the men for about 12 years" - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com.
  • Vitamin C and beta-carotene might protect against dementia - Science Daily, 9/11/12 - "A total of 74 AD-patients and 158 healthy controls were examined for the study that has been published in the Journal of Alzheimer's Disease (JAD) ... The concentration of vitamin C and beta-carotene in the serum of AD-patients was significantly lower than in the blood of control subjects. Whereas no such difference between the groups could be found for the other antioxidants (vitamin E, lycopene, coenzyme Q10)" - See Jarrow Formulas, CarotenALL at Amazon.com and vitamin C at Amazon.com.
  • Do Fruits and Veggies Make You More Attractive? - WebMD, 3/7/12 - "changes in the redness and yellowness of skin in white people may be linked to the number of servings of fruit and vegetables they eat on a daily basis. These antioxidant-rich foods, which are loaded with plant-based pigments, seem to affect skin tone ... They suggest it's the carotenoids -- the red, yellow, and orange pigments in fruits and vegetables -- that play an important role in skin tone. Foods such as carrots, sweet potatoes, squash, and apricots are rich in beta-carotene, as are some dark green vegetables, including spinach and kale ... Another carotenoid is lycopene, which is found in tomatoes and pink grapefruits" - See Jarrow Formulas, CarotenALL at Amazon.com and Garden of Life, Radical Fruits Antioxidant Complex at Amazon.com.
  • Repeated measurements of serum carotenoid, retinol and tocopherol levels in relation to colorectal cancer risk in the Women's Health Initiative - Eur J Clin Nutr. 2011 Dec 14 - "Previous cohort studies examining the association of serum antioxidant levels and risk of colorectal cancer have used a single (baseline) measurement only. In the present study, we assessed the association of serum levels of eight antioxidant nutrients in relation to risk of colorectal cancer, using repeated measurements ... Serum antioxidants measured at baseline generally showed no association with risk of colorectal cancer, although serum β-carotene at baseline showed a non-significant inverse association with colon cancer alone. Furthermore, using the repeated measurements of β-carotene, the average of all measurements was inversely associated with risk of both colorectal and colon cancer: HRs for highest vs lowest tertile 0.54, 95% CI 0.31-0.96, and 0.47, 95% CI 0.25-0.88, respectively. No associations were seen with other antioxidant nutrients in the repeated measure analyses" - See Jarrow Formulas, CarotenALL at Amazon.com.
  • Zeaxanthin Supplements as Effective as Lutein in AMD - Medscape, 11/1/11 - "Both lutein and zeaxanthin are carotenoids found in the color pigment of the eye ... Using a visual test designed to identify early signs of AMD, the researchers found that the vision in the zeaxanthin group sharpened from 0.97 to 0.57 (P > 0.06, 1-tail)" - See Jarrow Formulas, CarotenALL at Amazon.com.
  • Meta-analysis supports lutein’s eye health benefits - Nutra USA, 10/3/11 - "The new meta-analysis pooled data from only six longitudinal cohort studies. Crunching the numbers showed that the highest intakes of lutein and zeaxanthin were not associated with a reduced risk of early AMD ... On the other hand, the highest intake of these carotenoids was associated with 26% reduction in the risk of late AMD, and a significant reduction in the risk of neovascular AMD" - [Abstract] - See Jarrow Formulas, CarotenALL at Amazon.com.
  • Beta-carotene research shows conflicting results; dose and duration questions remain - Nutra USA, 3/16/11
  • Study unlocks lycopene’s heart health benefits - Nutra USA, 1/28/11
  • Eating vegetables gives skin a more healthy glow than the sun, study shows - Science Daily, 1/11/11 - "people who eat more portions of fruit and vegetables per day have a more golden skin colour, thanks to substances called carotenoids. Carotenoids are antioxidants that help soak up damaging compounds produced by the stresses and strains of everyday living, especially when the body is combating disease. Responsible for the red colouring in fruit and vegetables such as carrots and tomatoes, carotenoids are important for our immune and reproductive systems ... given the choice between skin colour caused by suntan and skin colour caused by carotenoids, people preferred the carotenoid skin colour"
  • Tomatoes found to contain nutrient which prevents vascular diseases - Science Daily, 1/6/11 - "Tomatoes are already known to contain many compounds beneficial to health. In this study the team analyzed 9-oxo-octadecadienoic acid, to test its potential anti-dyslipidemia properties ... The compound was found to enhance fatty acid oxidation and contributed to the regulation of hepatic lipid metabolism. These findings suggest that 9-oxo-octadecadienoic acid has anti-dyslipidemia affects and can therefore help prevent vascular diseases"
  • The effects of tomato consumption on serum glucose, apolipoprotein B, apolipoprotein A-I, homocysteine and blood pressure in type 2 diabetic patients - Int J Food Sci Nutr. 2010 Dec 8 - "32 type 2 diabetes patients received 200 g raw tomato daily for 8 weeks ... There were significant decreases in systolic and diastolic blood pressure and also a significant increase in apoA-I at the end of study compared with initial values"
  • High alpha-carotene levels associated with longer life - Science Daily, 11/22/10 - "Oxygen-related damage to DNA, proteins and fats may play a role in the development of chronic diseases like heart disease and cancer ... Carotenoids -- including beta-carotene, alpha-carotene and lycopene -- are produced by plants and microorganisms and act as antioxidants, counteracting this damage ... Compared with individuals with blood alpha-carotene levels between 0 and 1 micrograms per deciliter, the risk of death during the study period was 23 percent lower among who had concentrations between 2 and 3 micrograms per deciliter, 27 percent lower with levels between 4 and 5 micrograms per deciliter, 34 percent lower with levels between 6 and 8 micrograms per deciliter and 39 percent lower with levels of 9 micrograms per deciliter or higher" - Note:  There are over 600 carotenoids and some claim that taking large amounts of just one of them can cause a deficiency of the others. 
  • Lycopene-rich tomato paste helps skin from within: Study - Nutra USA, 9/23/10
  • Astaxanthin’s heart benefits get human data support - Nutra USA, 8/9/10 - "Daily supplements of the carotenoid astaxanthin may improve HDL ‘good’ cholesterol levels in people with mildly abnormal blood lipid levels ... participants receiving the two highest doses experienced significant reductions in their triglyceride levels, of 25 and 24 percent, respectively, compared to baseline. Furthermore, people receiving 6 or 12 mg per day experienced significant increases in their HDL-cholesterol levels of 10 and 15 percent, respectively ... Additionally, adiponectin levels increased in the two highest dose groups, with increases over 20 percent in the 12 mg per day group, and between 15 and 20 percent in the 18 percent group" - See Jarrow Formulas, CarotenALL, Mixed Carotenoid Complex at Amazon.com or astaxanthin at Amazon.com.
  • Carotenoids may reduce breast cancer risk in women: Study - Nutra USA, 2/8/10 - "The highest average levels of alpha- and beta-carotene were associated with a 68 and 65 per cent reduction in the risk of ER-PR breast cancer among smokers" - [Abstract] - See Jarrow Formulas, CarotenALL, Mixed Carotenoid Complex at Amazon.com.
  • Fruits, Leafy Greens Are Good for the Eyes - WebMD, 12/22/09 - "These foods contain the carotenoids such as lutein and zeaxanthin, which play an important role in vision and have a positive impact on the retina ... Lutein and zeaxanthin may help reduce disability and discomfort from glare, enhance contrast, and reduce photostress recovery times ... about 600 carotenoids can be identified in nature ... Lutein and zeaxanthin are found in kale and spinach, among other vegetables ... Of about 20 carotenoids found in human blood, only lutein and zeaxanthin are found in the visual system, the researchers write, suggesting these pigments play a "special role" in human vision"
  • Dietary carotenoids confirmed to benefit eye health: Study - Nutra USA, 12/22/09
  • Eat Fruits and Vegetable for Better Vision - Science Daily, 12/18/09 - "Carotenoids, found in green leafy vegetables and colored fruits, have been found to increase visual performance and may prevent age-related eye diseases ... macular pigments, such as lutein and zeaxanthin do have an effect on visual performance. Lutein and zeaxanthin can reduce disability and discomfort from glare, enhance contrast, and reduce photostress recovery times. They can also reduce glare from light absorption and increase the visual range"
  • Egg Yolks May Reduce Risk of Age-Related Macular Degeneration - Medscape, 11/13/09 - "Two eggs per day is probably all that is needed to maximize blood levels of lutein and zeaxanthin as well as macular pigment optic density (MPOD) status"
  • Lycopene linked to healthier blood vessels - Nutra USA, 8/13/09 - "Higher levels of lycopene in the blood are associated with lower stiffness in the arteries ... women with the highest average lycopene blood levels (more than 0.0431 millimoles per litre) had the lowest baPWV values, compared to people with the lowest average lycopene blood levels (less that 0.0342 mmol/L) ... According to their results, women with the highest average lycopene blood levels (more than 0.0431 millimoles per litre) had the lowest baPWV values, compared to people with the lowest average lycopene blood levels (less that 0.0342 mmol/L) ... these women also had lower oxidised LDL levels, as well as larger LDL particles ... Levels of C-reactive protein, a marker of inflammation, were also lower in the women with the highest lycopene levels" - See lycopene at Amazon.com.
  • Antioxidant vitamins may protect against female cancer - Nutra USA, 6/3/09 - "for every 1,000 microgram increase per 1,000 kcal of diet of beta-carotene was associated with a 12 per cent reduction in the risk of endometrial cancer ... Similarly, for every 50 milligram increase per 1,000 kcal of vitamin C the risk of endometrial cancer was reduced by 15 per cent, and for every 5 milligram increase per 1,000 kcal of vitamin E the risk of endometrial cancer was reduced by 9 per cent" - [Abstract]
  • Lutein, Zeaxanthin Supplements May Result in Better Macular Function in Early AMD - Medscape, 5/13/09 - "Although no statistically significant difference was seen in best corrected distance visual acuity (BC DVA) at 12 months, oral supplementation with lutein and zeaxanthin with coantioxidants may improve functional and morphologic outcomes at 36 months in patients at high risk for progression to late age-related macular degeneration (AMD) ... Results at 36 Months Significant" - See Jarrow Formulas, CarotenALL, Mixed Carotenoid Complex at Amazon.com.
  • Carotenoids linked to fewer hip fractures - Nutra USA, 3/26/09 - "higher lycopene intake was associated with a lower risk of hip fracture, and non-vertebral fracture ... a weak but statistically un-significant protective trend was recorded total beta-carotene, but only for hip fractures ... No protective effects were observed for the other carotenoids" - [Abstract] - See lycopene at Amazon.com.
  • Long-Term Use Of Nutrient Supplements May Increase Cancer Risk - Science Daily, 2/27/09 - "We believe beta-carotene is an antioxidant, but it seems that if you take too much, at some point it can have pro-oxidant effects, which can result in elevated cancer risk" - Note:  The problem with that study is that beta-carotene is just one of over 600 carotenoids and previous studies have shown that taking large quantities just one carotenoid can cause a deficiency of the others.  Those carotenoid deficiencies that it causes may be just as important if not more important in preventing cancer.  Plus it seems like an oxymoron to smoke and take vitamins.
  • Tomatoes for Endometriosis? - Dr. Weil, 2/13/09 - "A study from Wayne State University in Detroit suggests that lycopene, a powerful antioxidant and the carotenoid pigment that makes tomatoes bright red, can help prevent the scarring that occurs with endometriosis. In a laboratory study, researchers found that it reduced the formation of a protein that causes scar tissue and adhesions to develop by 80 to 90 percent" - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com.
  • Nutrient Supports Bone Health Over Time - Science Daily, 1/20/09 - "The results suggest there is a protective effect of carotenoids, particularly of lycopene, against bone loss in older adults. The researchers concluded that carotenoids may explain, in part, the previously observed protective effects of fruit and vegetable consumption on bone mineral density" - Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com.
  • LycoRed files patent for skin health science - Nutra USA, 11/7/08 - "According to LycoRed, subjects were supplemented by either Lyc-O-Mato capsules (10mg lycopene per day), or a placebo, for ten weeks. Following exposure to UV radiation at the end of the study, it was found that subjects in the tomato extract group had a sunburn cell count six times lower than in the placebo group. There was also evidence of reduced depletion of Langerhans cells, said the company" - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com.
  • Lycopene as effective as statins for artery health: rabbit study - Nutra USA, 7/3/08 - "The results of our experiment in the high-fat diet rabbit model showed that lycopene and fluvastatin lowered serum levels of total cholesterol and LDL-cholesterol, improved lipid metabolism, and reduced the amount of triacylglycerols ... Lycopene intervention reduced the increase in ox-LDL levels in rabbits on the high-fat diet, whereas fluvastatin did not show such an effect. The cause of this difference is at present not known, although the result speaks in favour of lycopene ... These findings provide a theoretical rationale for the use of lycopene as a preventive in atherosclerosis" - [Abstract] - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com.
  • Study supports lycopene protecting skin from within - Nutra USA, 4/29/08 - "Consuming lycopene-rich tomato paste may protect against sunburn and sun-induced skin ageing ... Skin samples taken from the subjects indicated that the tomato paste-supplemented individuals had higher skin levels of pro-collagen, a molecule which gives the skin its structure and loss of which leads to skin ageing and lack of elasticity" - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com.
  • Could foods prevent ovarian cancer? - MSNBC, 3/14/08 - "A 2007 study published in the British Journal of Nutrition linked greater consumption of carotenoid phytochemicals with a 67 percent lower risk of ovarian cancer. This included not only beta-carotene, the oft-cited carotenoid in deep-orange vegetables and fruits, but also alpha-carotene, beta-cryptoxanthin, lutein and zeaxanthin — carotenoids found in a wide range of red, orange, yellow and green vegetables" - See Jarrow Formulas, CarotenALL, Mixed Carotenoid Complex at Amazon.com.
  • Lutein, zeaxanthin for AMD protection: more science - Nutra USA, 3/13/08 - "people with the highest average intakes of dietary lutein and zeaxanthin had a 65 per cent reduced risk of neo-vascular AMD than those with the lowest average intakes" - [Abstract]
  • Vision: Antioxidants May Cut Cataracts - New York Times, 2/12/08 - "Compared with the one-fifth of women who consumed the least antioxidants, the one-fifth who consumed the most reduced their risk for cataracts by 14 percent with vitamin E and 18 percent with lutein"
  • Astaxanthin may boost muscle endurance and fat loss - Nutra USA, 2/5/08 - "astaxanthin supplementation "accelerated the decrease of body fat accumulation with exercise training" - [Abstract] - Note:  Astaxanthin is just one of over 600 carotenoids.  The problem with taking large doses of just one carotenoid is that it may cause a deficiency of the others.  I had a study on that but the link went dead.  I tried to find it via http://www.archive.org/web/web.php but it was a .asp web page and it appears that it doesn't work with those extensions. (Click here and see the OnHealth.com, 5/2/00 article).  I take Jarrow Formulas, CarotenALL, Mixed Carotenoid Complex at Amazon.com.
  • Eat Your Leafy Vegetables To Decreased Your Risk Of Cataracts - Science Daily, 1/14/08 - "When the participants were split into five groups based on the amount of lutein and zeaxanthin they consumed, those in the group who consumed the most (about 6,716 micrograms per day) had an 18 percent lower chance of developing cataracts than those who consumed the least (1,177 micrograms per day). The one-fifth who consumed the most vitamin E from food and supplements--about 262.4 milligrams per day--were 14 percent less likely than the one-fifth who got the least (4.4 milligrams per day)"
  • More support for lycopene's prostate benefits - Nutra USA, 1/9/08 - "At the end of the six month intervention period ... levels of prostate-specific antigen (PSA), a marker of prostate health, were reduced in the lycopene group showing improvements in health of the tissue. However, no changes were recorded in the placebo group ... Moreover, no enlargement of the prostate occurred in the lycopene group, whereas growth was observed in the placebo group" - [Abstract] - See Jarrow Lyco-Sorb at Amazon.com.
  • Long-term Beta Carotene Supplementation May Help Prevent Cognitive Decline, Study Suggests - Science Daily, 11/12/07 - "placebo or 50 milligrams of beta carotene every other day ... In this generally healthy population, the extent of protection conferred by long-term treatment appeared modest; nonetheless, studies have established that very modest differences in cognition, especially verbal memory, predict substantial differences in eventual risk of dementia; thus, the public health impact of long-term beta carotene use could be large" - Note:  The problem with beta-carotene is that it is just one of over 600 carotenoids and some studies show that taking large doses of just on carotenoid can cause a deficiency of the others.
  • Nutrients May Help Save Eyes - WebMD, 9/11/07 - "Those with the highest self-reported intake of foods rich in lutein and zeaxanthin were 35% less likely than those with the lowest lutein and zeaxanthin intake to have "wet" age-related macular degeneration"
  • Certain Nutrients Associated With Reduced Risk For Age-related Eye Disease - Science Daily, 9/10/07 - "If these cross-sectional results can be confirmed in prospective samples and experimental studies, lutein and zeaxanthin may be considered as useful agents in food or supplement-based interventions designed to reduce the risk of AMD"
  • Compounds That Color Fruits And Veggies May Protect Against Colon Cancer - Science Daily, 8/19/07 - "In animal studies, rats induced with colon cancer cells were fed a daily diet of anthocyanin extracts either from bilberries and chokeberries, which are most often used as flavorings or to make jams and juices. The dietary addition of the anthocyanin extracts reduced signs of colon tumors by 70 and 60 percent, respectively, when compared to control rats"
  • Lutein and Zeaxanthin review - ConsumerLab.com, 7/17/07
  • Prostate Cancer Confusion? - Dr. Weil, 6/18/07 - "while these investigators concluded that on the basis of their retrospective analytical methods lycopene and other carotenoids had no effect on prostate cancer, we have very good evidence from other studies that lycopene does in fact lower the risk"
  • No Magic Tomato? Study Breaks Link Between Lycopene And Prostate Cancer Prevention - Science Daily, 5/17/07
  • Could Carrots Be The Secret To A Long-life And Sex Appeal? - Science Daily, 5/10/07 - "males eating more carotenoids were better able to protect their cells from damage and so lived longer - and that females found these long-lived males particularly attractive"
  • Beta-Carotene Pills May Not Help Aging Eyes - WebMD, 3/14/07 -  "The difference between the two groups was so small that it could have been due to chance" - Note:  Beta-carotene is just one of over 600 carotenoids and many believe that taking mega-doses of just one carotenoid can cause a deficiency of the others.  I get my carotenoids from food, dunaliella salina algae (Body Wise), Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com, carotenoids at Amazon.com and Jarrow Formulas, CarotenALL at Amazon.com.
  • Tomato extract could stop platelet build-up, boost heart health - Nutra USA, 9/25/06 - "significant reductions in the build-up of platelets (stimulated by administration of ADP and collagen) were observed three hours after supplementation with tomato extract equivalent to two and six tomatoes (by 21.3 per cent for six tomato equivalents, and 12.7 per cent for the two tomato equivalents for the ADP administered groups, and by 17.5 per cent for six tomato equivalents, and 7.8 per cent for the two tomato equivalents for the collagen administered groups), while no significant effects were measured for control group"
  • Lutein skin health study elicits excited response at conference - Nutra USA, 9/13/06 - "the oral lutein supplement was seen to increase skin hydration by 38 per cent, skin elasticity by 8 per cent, and the level of superficial lipids by 33 per cent (after adjustments for placebo)"
  • Study boosts lutein safety rep and finds new research possibilities - Nutra USA, 7/20/06
  • Carotenoids linked to lower risk of non-Hodgkin lymphoma - Nutra USA, 6/12/06 - "High daily intakes of the carotenoids lutein and zeaxanthin, as well as vegetables in general, could reduce the risk of non-Hodgkin lymphoma by almost 50 per cent"
  • What causes age spots and is there anything that I can do to make them go away? - Dr. Murray
  • Study sheds light on lutein's anti-inflammatory effect - Nutra USA, 5/22/06
  • More support for lycopene protection against prostate cancer - Nutra USA, 5/3/06 - "half of these men to receive a daily supplement of eight milligrams of lycopene (LycoRed's Lyc-O-Mato) for one year and followed for a futher year ... blood levels of prostate-specific antigen (PSA), a protein that is used as a marker for the disease, decreased by 42 per cent after supplementation" - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com which contains Lyc-O-Mato.
  • Prostate tumours shrunk by lycopene, vitamin E combo - Nutra USA, 4/14/06 - "Compared with the control, the combined mixture of lycopene and vitamin E, at five mg/kg BW each, suppressed the growth of the prostate xenograft by 73 per cent at day 42 ... the mice receiving the combined supplement also lived 40 per cent longer"
  • Tomato Juice Keeps Emphysema From Developing In New Model; Lycopene Cited - Science Daily, 1/25/06 - "50% tomato juice drink "completely prevented" smoke-induced emphysema" - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com.
  • Tomato Juice Might Protect Lungs - HealthDay, 1/9/06 - "Tomato juice prevented emphysema in mice exposed to cigarette smoke ... They attributed the protective effect to lycopene"
  • Brightly-coloured Fruit And Veg May Protect Against Arthritis - Science Daily, 9/27/05 - "eating more brightly-coloured fruits and vegetables like oranges, carrots and sweetcorn may help reduce the risk of developing inflammatory disorders like rheumatoid arthritis ... the average daily beta-cryptoxanthin intake of the 88 patients who had developed inflammatory polyarthritis was 40% lower than those who hadn't, and their intake of another carotenoid, zeaxanthin, was 20% lower"
  • Smoking Plus Beta-Carotene May Up Cancer Odds - WebMD, 9/20/05 - "high beta-carotene intake (from foods or supplements) was linked to low levels of cancer in nonsmoking women and high levels of the same cancers in women who smoke"
  • Recently I have seen lycopene products being touted for their anticancer and antioxidant properties. Are these claims valid? - Dr. Murray
  • Carotenoid combo reduces damage to cells, may fight disease - Nutra USA, 3/15/05 - "The mixed carotenoids supplemented group showed significantly decreased DNA damage as early as day 15 (by around 22 per cent) and this further decreased at days 29 and 43. By day 57, it had been reduced by 36 per cent"
  • Antioxidant levels key to prostate cancer risk in some men - Nutra USA, 3/15/05 - "Greater levels of selenium, vitamin E and the tomato carotenoid lycopene have been shown to reduce prostate cancer in one out of every four Caucasian males, or those who inherit a specific genetic variation that is particularly sensitive to oxidative stress"
  • Lycopene intake linked to lower pancreatic cancer risk - Nutra USA, 3/10/05 - "lycopene, provided mainly by tomatoes, was associated with a 31 per cent reduction in pancreatic cancer risk among men in the highest quartile of intake compared with those in the lowest quartile"
  • Protective Effects of Oral Antioxidants on Skin and Eye Function - Medscape, 12/17/04 - "Carotenoids used as nutritional supplements seem to play an interesting photoprotective role for both skin and eyes"
  • Eat Spinach, Prevent Cataracts? - WebMD, 12/3/04 - "Our results are the first to provide physical evidence suggesting that lutein and zeaxanthin decrease damage caused by ultraviolet radiation"
  • Lycopene, Nature’s Most Potent Antioxidant Shows Broad Disease-Preventive Effects - Life Extension Magazine, 12/04
  • Vitamin E + Lycopene Fights Prostate Cancer - WebMD, 9/30/04 - "a combination treatment with low-dose lycopene and vitamin E had the strongest effect at slowing tumor growth -- a 73% slowing of growth on the 42nd day of the test ... The next best results came from the low dose of lycopene alone, which slowed tumor growth by 53% in the same time frame"
  • Long-Term Use of Beta Carotene Beneficial - Clinical Psychiatry News, 9/04 - "there was a highly significant improvement in cognitive scores—particularly in verbal memory—among the 2,029 men with long-term exposure to the supplements, compared with the 2,020 who had been taking placebo for nearly two decades"
  • Update on Lycopene - Dr. Murray's Natural Facts, 8/25/04 - "men who consumed the highest levels of lycopene (6.5 mg per day) in their diet showed a 21 percent decreased risk of prostate cancer compared with those eating the lowest levels. When the researchers looked at only advanced prostate cancer, the high lycopene eaters had an 86% decreased risk" - See iHerb lycopene products.
  • Lutein, zeaxanthin appear to restore eye cell health - Nutra USA, 8/25/04 - "Lutein and zeaxanthin are the primary components of macular pigment and have been associated with a reduced risk of age-related macular degeneration (AMD), the leading cause of vision loss for people over the age of 50 in the Western world"
  • Full-Fat Salad Dressings Enhance Bioabsorption of Carotenoids - Medscape, 8/5/04 - "By choosing reduced-fat or fat-free salad dressings, consumers could potentially compromise their exposure to the putative bioactivity of those carotenoids in preventing heart disease, cancer, and other chronic diseases"
  • A Little Fat Helps the Vegetables Go Down - WebMD, 7/27/04
  • ISU Research Says Fat Good With Veggies - Intelihealth, 7/26/04 - "A bit of fat added to fresh vegetables helps bodies absorb cancer-fighting lycopene and alpha- and beta-carotenes"
  • Carotenoids play role in cell communication - Nutra USA, 7/20/04
  • Major study backs carotenoids' protective effects on heart - Nutra USA, 6/14/04
  • Breakthrough research on lycopene - Nutra USA, 4/15/04 - "Men eating four to five tomato based-dishes per week were found to be protected by 25 per cent compared to men eating tomatoes only rarely" - See iHerb lycopene products.
  • Carotenoids Reduce HPV Symptoms - Physician's Weekly, 2/16/04 - "Patients who increased their intake of vitamin C and consumed carotenoid-rich papaya at least once per week had a lower risk of persistent HPV in the study"
  • The Prostate Cancer-Fighter - WebMD, 11/4/03 - "in rats made to develop prostate cancer in the laboratory, those who were fed a diet containing tomato powder experienced a longer survival prior to developing cancer and were 26% less likely to die from prostate cancer compared with those on a "control" diet containing no tomato or lycopene foods ... In rats fed a diet of lycopene alone, the death rates from prostate cancer were similar to those rats fed a control diet"
  • Pizza Prevents Cancer? It's Part of the Mediterranean Diet - WebMD, 7/21/03 - "Gallus and colleagues sifted through diet surveys completed by 5,500 Italians ... regular pizza eaters had 34% less risk of oral cavity and pharyngeal cancer, 59% less risk of esophageal cancer, and 25% less risk of colon cancer ... Italian pizza is less than 50% crust, 20% tomato sauce, 20% mozzarella cheese, and 4% olive oil ... There's less refined carbohydrates, plus cooked tomatoes, which are a rich source of lycopene, a natural chemical that has been shown in numerous studies to protect against cancer ... We think that there's a specific compound in cooked tomatoes that is protective"
  • What do you think of the new study showing that antioxidants don’t cut the risk of heart disease - Dr. Weil, 7/14/03 - "If you want to supplement your diet, take a product that provides as many members of this family of protective pigments as possible: alpha-carotene, lutein, zeaxanthin, lycopene, etc. As for vitamin E, most studies use synthetic alpha-tocopherol. I recommend using natural vitamin E supplements that provide all four tocopherols and all four tocotrienols"
  • Beta-Carotene and Other Carotenoids Protect Skin from Ultraviolet Damage - New Hope Natural Media, 3/13/03 - "36 adults between the ages of 22 and 55 were assigned to receive one of the following: (1) 24 mg per day of beta-carotene, (2) a mixed carotenoid supplement containing 8 mg per day each of beta-carotene, lutein and lycopene, or (3) a placebo for 12 weeks. Skin redness before and 24 hours after irradiation with UV light was measured initially and after 6 and 12 weeks of supplementation ... Both groups that took the nutritional supplements containing carotenoids had a significant decrease in UV light-induced redness of the skin after 12 weeks of treatment ... since lutein and lycopene are found in high amounts in other organs, the health benefits of these substances may go beyond just protecting the skin" - [Abstract]
  • Lutein for Cataract Sufferers - New Hope Natural Media, 3/13/03 - "15 individuals with age-related cataracts were randomly assigned to receive either 15 mg of lutein, 100 IU of vitamin E, or a placebo three times per week for up to two years. Visual acuity improved significantly in the lutein group, whereas no change was seen in the vitamin E and placebo groups"
  • Wow, You Coulda Had Some Lycopene! - Cancer Decisions Newsletter , 1/7/03 - "Men who received the lycopene supplement had lower prostate-specific antigen (PSA) levels and less aggressive tumors than the non-supplemented control group. Their tumors were smaller (80 percent of the tumors were under 4 milliliters (ml) in volume, compared to 45 percent in the control group). Their cancer was much more likely to be within the surgical margins and/or confined to the prostate gland (73 percent, compared to 18 percent of the control group). And the invasion of the prostate gland by cancer-like "PIN" cells was completely prevented in this group, compared to a 33 percent incidence of "PIN" cells in the control group" - See iHerb lycopene products.  My favorite is Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com, which has the brand name Lyc-O-Mato.
  • A Better Antioxidant [astaxanthin]? - Dr. Weil, 12/12/02 - "to my knowledge none of the specific claims for astaxanthin as a superior antioxidant have been proved in humans ... However, I do think we all need to make an effort to eat more foods containing carotenoids, including astaxanthin"
  • Watermelon for Prostate Cancer? - Dr. Weil, 12/10/02 - "Lycopene is a powerful antioxidant that a number of large studies have shown is particularly good at protecting against prostate, colon and rectal cancer, as well as heart disease ... contains 40 percent more lycopene than an equivalent weight of tomatoes ... The body converts about 500 different carotenoids into vitamin A ... If you don’t get enough of these foods in your diet, you may want to use an antioxidant supplement. I recommend a mixed carotenoid supplement containing lycopene, lutein, alpha-carotene, and zeaxanthin, as well as beta-carotene"
  • Cancer Researchers Keen on Tomatoes - WebMD, 11/11/02 - "For example, a five-year Japanese study shows daily use of a supplement that contained a combination of natural tomato extract, beta-carotene, and vitamin E might be an effective way to reduce the risk of liver cancer in those at risk. Researchers found that patients who received the supplement had a 50% suppression of liver cancer" - See iHerb lycopene products.
  • Should Smokers Avoid Beta-Carotene? - Dr. Weil, 9/12/02
  • Carotenoid-Rich Foods Protect Against Oxidative Stress, but Carotenoids Alone Don't Provide Benefit - Doctor's Guide, 7/3/02
  • High Oxidative Stress, Low Antioxidant Status In Alzheimer Disease - Doctor's Guide, 6/3/02 - "Lymphocyte DNA 8-OHdG content in people AD may thus reflect a condition of increased oxidative stress related to a poor antioxidant status ... researchers also noted a significant inverse relationship between lymphocyte DNA 8-OHdG content [a marker of oxidative damage to DNA] and plasma levels of lycopene, lutein, a-carotene and b-carotene, respectively"
  • Breast Cancer May Be Thwarted By Carotenoids - Doctor's Guide, 5/23/02 - "These results suggest carotenoids may protect against development of breast cancer"
  • Macular Degeneration Epidemic - Life Extension Magazine, 5/02 - "AMD patients who have begun taking high-dose lutein supplements (4 mg or more per day) appear to return to 'normal' levels after a few months. These findings are consistent with the hypothesis that a long-term deficiency of macular carotenoids may be associated with higher risk of AMD"
  • Common Foods Help Prevent Cancer - WebMD, 4/10/02 - "found that regular green tea drinking cut cancer risk in half ... men who ate more than two servings of tomato sauce per week had a 23% lower risk of prostate cancer than men who ate less than one serving a week"
  • Tomatoes Lower Prostate Cancer Risk - WebMD, 3/4/02 - "This newest investigation "confirmed our previous findings," ... "Frequent tomato or lycopene intake was associated with a reduced risk of prostate cancer. Intake of tomato sauce, the primary source of [ready available] lycopene, was associated with an even greater reduction in prostate cancer risk." ... Although all evidence points to lycopene as the beneficial ingredient, that remains to be proved" - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com.
  • Lycopene lowers PSA - Life Extension Magazine, 1/02 - "32 mostly African American patients who had been diagnosed with prostate cancer and were awaiting radical prostatectomy were put on diets that included enough tomato sauce to provide 30 mg/day of lycopene for three weeks. Prostate cancer is more frequent and serious among African Americans than among Caucasians ... Mean serum PSA concentrations fell by 17.5%, while a measure of oxidative status fell by 21.3%. DNA damage in the cancer cells fell by 40% after three weeks, of which author Phyllis E. Bowen says, “We don’t know whether that’s good or bad.” Most important, high concentration of lycopene in prostate tissues resulted in a nearly three-fold increase in programmed cell damage among cancer cells, which is a good thing"
  • Pasta Treatments for Prostate Cancer - WebMD, 12/18/01
  • The Wizard is Oz - Life Extension Magazine, 11/01 - "Best-selling author and nutritional guru to the rich and famous, Oz Garcia is singing the praises of the Life Extension Foundation and its products in his newest book, The Healthy High Tech Body, published in September 2001 ... Supplements at the top of Garcia's list of recommendations ... DHA ... NADH ... Alpah Lipoic Acid ... Acetyl-L-Carnitine ... An expanded list of his recommendations includes lycopene, gamma tocopherol, vinpocetine, SAMe, folic acid, carnosine, glutathione, DMAE, Huperzine A, probiotics, MSM, secretagogues, arginine pyroglutamate, IP-6, bioflavonoid formulas and grape skin/seed extracts"
  • Antioxidants, At Certain Levels, May Reduce Blood Pressure - Doctor's Guide, 11/14/01 - "increasing levels of serum beta- carotene were associated with significant reductions in systolic blood pressure, while increasing levels of serum vitamin C were associated with significant reductions in diastolic pressure ... In contrast, serum levels of vitamin E were associated with significant increases in diastolic blood pressure"
  • Carrots, tomatoes keep lung cancer away - Life Extension Magazine, 9/01
  • Scientists Think Roadside Berries Could Be Cancer Fighter - Intelihealth, 9/14/01
  • Study Provides New Evidence That Chemical In Tomato Sauce May Help Fight Prostate Cancer, Particularly In Black Men - Intelihealth, 8/30/01 - "Researchers at the University of Illinois in Chicago fed 32 volunteers with newly diagnosed prostate cancer three-fourths cup of tomato sauce daily for three weeks ... the treatment resulted in reduced blood levels of prostate specific antigen (PSA), a protein whose increased levels are strongly linked to a higher prostate cancer risk ...Researchers believe that lycopene, a red pigment with high antioxidant potential, is the most likely agent involved in this effect"
  • Tomato Extract May Have Role in Slowing Prostate Cancer - WebMD, 8/10/01 - "So when the results came in, Kucuk and colleagues were startled: the men who used the lycopene supplement actually had smaller tumors than the men who did not. Even more intriguing, the tumors taken from the men who used lycopene supplement were more likely to be confined to the prostate, and less likely to have advanced beyond it."
  • Newly Hip Nutrient May Stave Off Heart Disease - WebMD, 6/21/01 - "the team gave lutein supplements to two types of heart-disease prone mice. These treated mice had significantly less atherosclerosis than did similar mice that hadn't received the supplemental lutein"
  • Eye-opening Zeaxanthin - Nutrition Science News, 6/01
  • Tomatoes May Help Fight High Blood Pressure - Doctor's Guide, 5/20/01 - "patients were treated with a placebo for four weeks and then tomato extract (Lyc-O-Mato, LycoRed Natural Products Industries, Ltd.), for eight weeks ... Results showed a significant reduction in systolic blood pressure, from 144 mm Hg to 135 mm Hg, representing a mean 9 mm Hg reduction. Additionally, some favorable effects on diastolic blood pressure, blood lipids, lipoproteins, and oxidative stress markers were noted" - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com, which contains the Lyco-O-Mato.
  • Ulcer Therapy, Vitamins May Team Up to Prevent Stomach Cancer, Drugs Halted, Healed Abnormalities With Cancer Potential - WebMD, 12/8/00 - "people who took the three-drug combination alone or in combination with vitamin C and/or beta carotene were three to five times more likely than people who received no treatment to have a reduction in the size of precancerous stomach abnormalities."
  • Looking For Supplements That Aid Vision - OnHealth.com, 5/2/00 - "There are over 600 carotenoids in the food we eat," says Dr. Donald S. Fong, a California ophthalmologist who has done research at the National Institutes of Health on the importance of nutrients in retinal diseases. "So if you supplement with high doses of any single one, you block the absorption of other carotenoids you may need. And, in addition, you might increase the risk of disease in other parts of the body." (a good reason to go with a supplement like Body Wise, which has dunaliella salina algae for mixed carotenoids).

Abstracts:

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