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Home > Anti-aging Research > Fatty Acids

Omega-3 - Alpha Linolenic Acid, Eicosapentaenoic acid, Docosahexaenoic acid, Docosapentaenoic acid

See my essential fatty acids page for a brief summary of EFAs.

Related Topics:

Specific Recommendations:

Omega 3 in various fish oil capsules as a percentage of the total fat in the capsule

Brand

Total omega 3 EPA DHA Other omega 3 (DPA and ALA)
Twinlab TwinEPA (vcicon) 1,000 mg capsule 840/1000 = 84% 600/1000 = 60% 240/1000 = 24% 0%
Jarrow Max DHA * 500 mg capsule 400/500 = 80% 100/500 = 20% 250/500 = 50% 50/500 = 10%
Sun Ultra DHA 50 * 500 mg capsule 400/500 = 80% 100/500 = 20% 250/500 = 50% 50/500 = 10%
Sun Ultra 30/20 * 1,000 mg capsule 600/1000 = 60% 300/1000 = 30% 200/1000 = 20% 100/1000 = 10%
Source Naturals EPA 1,000 mg capsule 600/1000 = 60% 450/1000 = 45% 100/1000 = 10% 50/1000 = 5%
RxOmega-3 1,000 mg capsule 630/1065 = 59% 400/1065 = 38% 200/1065 = 19% 30/1065 = 3%
LEF Mega EPA 1,200 mg capsule 700/1200 = 58% 400/1200 = 33% 300/1200 = 25% 0%
Enzymatic Eskimo-3 500 mg capsule 200/500 = 40% 87/500 = 17% 55/500 = 11% 58/500 = 12%
NSI Superior EFAicon 1,000 mg capsule 400/1000 = 40% 100/1000 = 10% 250/1000 = 25% 50/1000 = 5%
Carlson Norwegian Salmon Oil 1,000 mg capsule 375/1000 = 38% 180/1000 = 18% 125/1000 = 13% 70/1000 = 7%
Twinlab Super MaxEPA (vcicon) 1,200 mg capsule  375/1200 = 31% 225/1200 = 19% 150/1200 = 12% 0%
Sun Ultra Omega 3 1,000 mg capsule 300/1000 = 30% 180/1000 = 18% 120/1000 = 12% 0%
Zone Perfecticon * 1000 mg capsule 267/1000 = 27% 160/1000 = 16% 107/1000 = 11%  
Now Foods Salmon Oil 400/2000 = 20% 240/2000 = 12% 160/2000 = 8% 0%

Vegetable oils (note that the omega 3 is in the form of ALA.  See "General Information" below for why this might not be as good)

Source Natural Omega Flaxicon 1,000 mg capsule 570/1000 = 57% 0% 0% 570/1000 = 57% (ALA)
Canola Oil 10% 0% 0% 10% (ALA)

vc - Vitacost price
* Molecular Distillation

CME:

  • Omega-3 Fatty Acids in the Management of Hypertriglyceridemia: New Findings and Formulations - Continuing Medical Education (CME):Princeton Media Associates, exp. 10/29/06 - "To lower TG levels, the dose of omega-3 therapy is ~4 g of EPA + DHA per day"
  • Omega-3 Fatty Acids: Recommendations for Therapeutics and Prevention - Medscape, exp. 10/19/06 - "Studies support low DHA as a risk factor for dementia. Low total n-3 fatty acids levels, EPA and DHA associate with greater risk of CVD, dietary intake and/or supplementation is supported as a secondary or tertiary prevention measure. Omega-3 fatty acids also help to prevent type 2 diabetes and the metabolic syndrome, two common precursors to CVD. There is some support for schizophrenia, depressive or aggressive disorders; however, large multi-center clinical trials have yet to be conducted. The anti-inflammatory properties of n-3 fatty acids are helpful in decreasing symptoms of rheumatoid arthritis and may possibly increase remission length in Crohn's patients"
  • Omega 3: Implications in human health and disease - PowerPak (CME course), exp. 8/1/03 - "On average, our society consumes around 35% of its caloric intake from fat, mainly as vegetable oil. The omega 6 LA comprises 7% to 9% of our daily caloric intake, while the omega 3 LNA makes up about 0.7% of energy. It is therefore estimated that the dietary ratio of LA to LNA ranges from 10 to 20:1, at which level the metabolism of LNA is strongly suppressed.2,25 Again, this is far more than the recommended ratio of 2.3:1" - See Mega Twin EPA at Vitacosticon or iHerb.

General Information:

  • Depression Protocol - Life Extension Foundation
  • Fish Oil and Cod Liver Oil (EPA & DHA)icon - Vitacost Health Library
  • An Evidence-Based Medicine Approach to the Appropriate Selection of Supplementation with Omega-3 Fatty - PowerPak.com, 6/1/07 - "Fish oils EPA and DHA appear to result in different physiologic effects than their precursor, the plant-derived ALA.12-14 Biosynthesis of EPA or DHA from ALA is limited. Although dietary consumption of ALA alone will prevent EFA deficiency, emerging scientific evidence indicates that for optimum health or body function, the fish oils EPA and DHA should also be ingested regularly, either from dietary or supplement sources. Use of ALA supplementation alone, even with high dose or long-term consumption, does not result in lowered triglyceride concentrations seen with EPA or DHA, nor does it demonstrate similar in vitro susceptibility to oxidation of LDL cholesterol"
  • The Heart-Healthy Benifits of Omega-3 Fatty Acids - John Hopkins University School of Medicine, 6/05 - "Fish-oil supplements appear to have much lower levels of toxins than fish. In a study of 5 over the-counter fish-oil preparations, levels of PCBs and organochlorines were below the detectable limit in all of the supplements ... Because consumption of this amount of fish in secondary prevention is difficult for most individuals, dietary supplementation is generally needed and should be recommended. The dose in secondary prevention should be at least 875 mg of EPA + DHA per day. This dose can generally be obtained by taking 2 capsules of concentrated fish oils (at least 50% EPA + DHA) per day. For example, such a preparation would contain 500 mg of EPA + DHA per each 1000-mg fish-oil capsule"
  • Omega 3: Implications in Human Health and Disease - PowerPak.com - "It should be noted, however, that flaxseed or flaxseed oil does not contain EPA or DHA. Thus flaxseed and fish oil are not interchangeable sources of omega 3 fatty acids per se" - I believe the same holds true for canola oil - Ben
  • Omega 3: Implications in Human Health and Disease -PowerPak.com -"The omega 6 LA comprises 7% to 9% of our daily caloric intake, while the omega 3 LNA makes up about 0.7% of energy. It is therefore estimated that the dietary ratio of LA to LNA ranges from 10 to 20:1, at which level the metabolism of LNA is strongly suppressed. Again, this is far more than the recommended ratio of 2.3:1 ... From an evolutionary perspective, a significant change in the diet has occurred in a very short time. The diet of our ancestors in the Paleolithic period (400,000 to 45,000 years ago) was lower in fat and balanced in omega 6 and omega 3—a ratio of 1:1, or 10- to 20-fold lower than today's standard."
  • THE A-Z's of OMEGA-3's - bipolarchild.com, Spring 2001
  • Omega-3 Fatty Acids - Pharmaceutical Grade Marine Lipids - Dr. Murray (.pdf)
  • Omega-3 Fatty Acids - The Natural Pharmacist
  • Heart Health - Fish Oil - natmedonline.com

News & Research:

  • Omega-3 carrier key to boosting children's attention: study - Nutra USA, 5/15/08 - "Test of Variables of Attention (TOVA) scores ... In terms of attention measures, both omega-3 supplemented groups produced increased in TOVA scores, with an increase of 94 per cent in the PL-omega-3 group and 37 per cent in the fish oil group" - [Abstract]
  • Diets With High Omega-6:Omega-3 Ratios Enhance Risk for Depression, Inflammatory Disease - Medscape, 4/25/08 - "Whereas the early hunter-gatherers had a dietary omega-6:omega-3 ratio of 2:1 to 3:1, this ratio is now 15:1 to 17:1 in North America today ... It is believed that these dietary changes might be related to increases in inflammatory-related diseases, including depression and cardiovascular disease ... at higher levels of depressive symptoms, as the omega-6:omega-3 ratio increased, there was a marked increase in proinflammatory cytokine levels ... compared with the study participants who did not have syndromal depression, the 6 participants who had depression had significantly higher omega-6:omega-3 ratios and higher levels of proinflammatory cytokines"
  • Dietary Fish Oil Has Antiarrhythmic Effects in Ischemic Heart Disease - Medscape, 4/22/08 - "This stabilizing effect may be one way in which fish oil reduces mortality in patients with coronary artery disease"
  • Omega-3 EPA may benefit depressives, says study - Nutra USA, 4/7/08 - [Abstract] - "were randomly assigned to receive a daily EPA supplement (1000 mg, supplied by Minami Nutrition, Belgium), or 20 mg fluoxetine daily, or a combination of the two for two months ... At the end of the study, data from the 48 people who finished the study showed a 50 per cent reduction in HDRS scores for people in the EPA group, a 56 per cent reduction in people in the fluoxetin group, and a 81 per cent reduction in people in the combined intervention group"
  • Mom's fish intake may boost child's brain power - MSMBC, 4/1/08 - "Preschoolers whose mothers regularly ate low-mercury fish during pregnancy may have sharper minds than their peers ... Oily fish such as tuna, salmon and sardines contain omega-3 fatty acids, which are important in fetal and child brain development. The problem is that fatty fish are more likely to be contaminated with mercury, a metal that is toxic to brain cells, particularly in fetuses and young children"
  • Omega-3 Fatty Acids May Be Useful for Cardioprotection - Medscape, 3/18/08 - "To date, the strongest evidence showing a CV benefit from omega-3 fatty acid intake derives from 3 large controlled trials in which a total of 32,000 participants were randomized to a control group or to receive omega-3 fatty acid supplements containing DHA and EPA. In these trials, the supplemented group had a 19% to 45% reduction in CV events vs the control group ... Patients with hypertriglyceridemia should consume 3 to 4 g/day of DHA and EPA, which can lower triglyceride levels by 20% to 50%"
  • Fish Diet May Cut Sudden Coronary Death - WebMD, 3/12/08 - "Men who reported eating an average of 6 grams of fatty fish daily -- that's two servings, according to the U.S. Department of Agriculture's serving-size guidelines -- were 55% less likely than men who ate no fatty fish to die of sudden coronary death ... The researchers chalk up the results to the omega-3 fatty acids EPA and DHA" - See Mega Twin EPA at iHerb and Jarrow Max DHA at iHerb.
  • Cardiovascular Benefits Of Omega-3 Fatty Acids Reviewed - Science Daily, 3/12/08 - "The most compelling evidence for the cardiovascular benefit provided by omega-3 fatty acids comes from three large controlled trials of 32,000 participants randomized to receive omega-3 fatty acid supplements containing DHA and EPA or to act as controls ... These trials showed reductions in cardiovascular events of 19 percent to 45 percent ... keeping fish oil capsules in the freezer ... may help reduce burping and upset stomach symptoms" - I've always done the freezer thing and haven't had any problem with the burp even on an empty stomach.  Also note that it's the DHA and EPA that count.  I have friends that buy cheap fish oil capsules that have very low DHA and EPA (omega-3) and they think they are getting a great deal.  I take Jarrow Max DHA at iHerb and Jarrow Max DHA at iHerb.  They've got the highest percentage of omega-3 that I've found.
  • Typical North American Diet Is Deficient In Omega-3 Fatty Acids - Science Daily, 3/7/08 - "the typical North American diet of eating lots of meat and not much fish is deficient in omega-3 fatty acids and this may pose a risk to infant neurological development ... the women who ate lots of meat and little fish were deficient in omega-3 fatty acids, and their babies didn't do as well on eye tests as babies from mothers who weren't deficient. The results were noticeable as early as two months of age"
  • Farmed Fish Fed Cheap Food May Be Less Nutritious For Humans - Science Daily, 2/26/08 - "Vegetable oils have been shown to stimulate the appetite and feed intake of fish, and to increase growth rate and carcase quality ... Marine oils are rich in long-chain omega-3 fatty acids (EPA and DHA), which have been shown to have beneficial effects on heart and circulatory system disease in man ... heart patients with atherosclerosis (disease of the cardiac arteries) were placed on three different diets, using salmon meat containing varying amounts of fish oil and vegetable oil. It was shown that the fat composition of the salmon meat affected the fatty acid profile of the patients’ blood and that the advantageous marine omega-3 fatty acids increased markedly in those patients that ate fish fed on feed containing pure fish oils. It was also shown that in these patients the levels of marker substances for heart and vessel disease were much better than in patients eating fish fed pure rapeseed oil"
  • Consumption of fish/fish oil associated with specific heart-rate variability parameters - theheart.org, 2/21/08 - "fish and omega-3 fatty-acid consumption are associated with "more optimal" values of various heart-rate variability (HRV) indices" - [Abstract]
  • Essential Fatty Acid Accelerates Treatment Response in Early Psychosis - Medscape, 1/22/08 - "For the primary and secondary prevention of emerging psychotic disorders, physicians should "keep an open mind towards neuroprotective substances, such as omega-3 fatty acids or other experimental neuroprotective substances,""
  • Alpha-Linolenic Acid May Lower Risk of Diabetic Peripheral Neuropathy - Medscape, 1/7/08 - "Alpha-linolenic acid is an omega-3 fatty acid found in many vegetable oils, including flaxseed, walnuts, and canola oil ... Relative to adults in the lowest quintile of alpha-linolenic acid intake (< 0.61 g/day), the multivariate-adjusted odds of having peripheral neuropathy was 0.54 for subjects in the fourth quintile (1.35 - 2.10 g/day) of intake and 0.40 for adults in the fifth quintile (2.11 g/day or higher)" - See flax seed products at iHerb.
  • More support for omega-3 and weight management - Nutra USA, 12/21/07 - "Laboratory mice fed a high fat diet and supplemented with eight per cent fish oil gained less weight and metabolised more fat than their murine counterparts not receiving the supplement" - [Abstract]
  • How Much Fish Is Enough? - Medscape, 12/19/07 - "the American Heart Association recommends the equivalent of 1 gram of active omega-3 compounds (eicosapentaenoic [EPA] and docosahexaenoic acids [DHA]) ingested daily.[3] This amount can be obtained by consuming a 4-ounce serving of white albacore tuna, 2 to 3 ounces of salmon (pink or red), 2 ounces of herring, and 2 to 3 ounces of sardines daily. Alternatively, significantly higher quantities of shellfish would need to be consumed, including 8 or more ounces of crab, shrimp, and lobster daily.[3] For significant TG-lowering effects (20% reduction and greater), the amount of EPA/DHA required is considerably higher (ie, 2 to 4 grams daily) and exceedingly difficult to obtain unless a person consumes vast quantities of fish every day. Therefore, patients with CHD can get the omega-3 fatty acids needed from a diet rich in oily fish. Similarly, patients with TG levels in the borderline-elevated range (150-199 mg/dL) may reduce TG levels by approximately 10% with consumption of fish equivalent to 1 gram of EPA/DHA. However, with higher TG levels, and especially when levels exceed 500 mg/dL, a diet rich in fish is most likely to be insufficient for reducing TG levels to an acceptable range"
  • Omega-3 shows benefits for fat loss in diabetics - Nutra USA, 12/13/07 - "either daily supplements of fish oil (three grams, providing 1.8 grams of omega-3) or placebo (paraffin oil) for two months ... At the end of the study, Kabir and co-workers report significant reductions in total fat mass and the diameter of fat cells beneath the surface of the skin (subcutaneous adipocytes) in the omega-3, but not the placebo, group ... risk factors for plaque formation in the arteries (atherogenic markers), such as triacylglycerol levels and the ration of triacylglycerol to HDL ('good') cholesterol, were significantly lower as a result of omega-3 supplementation" - [Abstract]
  • Omega-3 Fatty Acids Protect Against Parkinson's, Study Says - Science Daily, 11/26/07 - "Omega-3 fatty acids protect the brain against Parkinson's disease ... omega-3 fatty acids--in particular DHA (docosahexaenoic acid), a specific type of omega-3--had replaced the omega-6 fatty acids already present in the brains of the mice that had been given omega-3 supplementation" - See Jarrow Max DHA at iHerb.
  • The Ethyl Ester vs. Triglyceride Form of Fish Oils - Dr. Murray's Natural Living, 11/21/07 - "Some fish oil products are made by synthesizing the free fatty acids back to a triglyceride form while others, including the pharmaceutical forms, maintain the purified oil in the ethyl ester (EE) form. Some companies selling fish oils claim that the triglyceride form is more natural, has better stability, and is better absorbed than the EE form. None of these claims is true. The recombined triglycerides are not necessarily in their natural form, they are not more stable, and they certainly are not better utilized by the body. My personal opinion is that the EE form actually possesses some advantages: ... The specific fish oil product that I recommend is RxOmega-3 Factors from Natural Factors" - See RxOmega-3 products at iHerb.
  • Fish for brain health supported by trio of studies - Nutra USA, 11/14/07 - "These recent reports are novel in that they address the association of n-3 fatty acid intake and cognitive function in non-demented individuals and, thus, present a shift in the attention to earlier stages of cognitive decline with the hope of preventing progression to states of dementia and disability before they become irreversible"
  • Eating Fish, Omega-3 Oils, Fruits And Veggies Lowers Risk Of Memory Problems - Science Daily, 11/13/07 - "people who regularly consumed omega-3 rich oils, such as canola oil, flaxseed oil and walnut oil, reduced their risk of dementia by 60 percent compared to people who did not regularly consume such oils ... people who ate fish at least once a week had a 35-percent lower risk of Alzheimer's disease and 40-percent lower risk of dementia, but only if they did not carry the gene that increases the risk of Alzheimer's, called apolipoprotein E4, or ApoE4 ... Given that most people do not carry the ApoE4 gene, these results could have considerable implications in terms of public health"
  • Omega-3 Fish Oil Improves Lupus Symptoms, Shows Possible Cardiovascular Benefits - Doctor's Guide, 11/12/07 - "They received 3 grams of omega-3 fish oils, daily, for 24 weeks ... Low dose dietary supplementation with omega-3 fish oils in SLE not only has a therapeutic effect on disease activity but also improves endothelial function and reduces oxidative stress and may, therefore, confer cardiovascular benefits" - See Mega Twin EPA at iHerb.
  • Got omega-3? Not so much - USATODAY.com, 11/11/07 - "Most mayonnaise is made with soybean oil, which is a source of ALA (alpha-linolenic acid). But that kind of omega-3 fat, found most abundantly in flaxseed, has not been proven to convey the same health benefits as DHA plus EPA ... if the label just says omega-3 and makes no mention of DHA and EPA, there's a good chance it's ALA"
  • Eat Fish, Get Smarter? - WebMD, 11/8/07 - "Most participants ate fish, and the more fish they ate, the better their test scores were -- up to a point ... Test scores leveled off for people who ate more than about 2.5 to 2.8 daily ounces of fish" - Note:  The article includes a total of three studies.
  • Staving Off Alzheimer's Disease With The Right Diet, Prescriptions - Science Daily, 11/7/07 - "Fish oil elevated the level of a protein that prevents the formation of amyloid, the tell-tale protein found in Alzheimer's. Caffeine reversed memory impairment in animal models of the disease. In addition, environmental copper reduced the clearance of amyloid, from the brain to blood ... scientists have identified ways that essential omega-3 fatty acid -- docosahexaenoic acid (DHA) or fish oil -- can help prevent Alzheimer's ... DHA also reduced pro-inflammatory arachidonic acid in brains of Alzheimer's model mice, consistent with the anti-inflammatory effects of non-steroidal anti-inflammatory drugs (NSAIDs) that are associated with reduced Alzheimer's in people" - See Jarrow Max DHA at iHerb.
  • Fish Oil Supplements May Ease Lupus - WebMD, 11/7/07 - "Fish oil supplements may help improve the symptoms of lupus ... the supplements also improve blood flow and blood vessel function in people with lupus who are known to be at increased risk for heart disease"
  • Fish May Be Adjunct for Postpartum Depression - Clinical Psychiatry News, 11/07 - "The only study of omega-3 fatty acid supplements given specifically for postpartum depression was a dose-ranging study in 16 women. It found significant and similar reductions in depression in each of three dosage groups; patients received between 500 mg and 2.8 g per day of supplement capsules for 8 weeks"
  • Omega-3 to cut colon cancer: meta-analysis - Nutra USA, 10/25/07 - "the highest consumption of fish oil was associated with 12 per cent reduction in the incidence of colorectal cancer" - [Abstract] - See Mega Twin EPA at iHerb.
  • Recurrence of Atrial Fibrillation Reduced With Alpha-Linolenic Acid-Enriched Diet - Doctor's Guide, 10/17/07 - "The survival rate was 25.52% in the control group versus 63.09% in the ALA group at the end of the 12-month period" - Note:  ALA is the shorter chain omega-3 found in vegetable sources such as flaxseed.
  • Baby Formula WIth Fish Oil Added May Help Infants - Science Daily, 10/11/07 - "The researchers noticed that in the piglets that were fed the control formula, fewer proteins were produced in their body over time and, at the same time, their insulin became less effective at lowering blood sugar levels. But piglets that drunk the test formula showed increased protein production and their insulin was as effective at using the proteins in the test formula for their growth as when they were born"
  • Vitamin C May Slow Skin Wrinkling - WebMD, 10/8/07 - "After adjusting for other factors likely to influence skin aging, such as sun exposure and smoking, vitamin C and linoleic acid were independently associated with skin aging ... After digestion, linoleic acid is converted to DHA and EPA -- two fatty acids" - See vitamin C products at iHerb and Mega Twin EPA at iHerb. - Note:  I'm not sure that is correct.  Linoleic acid is an omega-6, which is not converted to DHA and EPA.  Most Americans get about ten time too much omega-6 already.
  • Omega-3 Fatty Acids and Borderline Personality Disorder - Clinical Psychiatry News, 10/07 - "Omega-3 fatty acids may be effective for reducing aggression and depression in females who suffer with moderate BPD. The results are consistent with prior findings on the efficacy of omega-3 fatty acids in the treatment of depression (Evidence-Based Psychiatric Medicine, CLINICAL PSYCHIATRY NEWS, May 2005, p. 28)"
  • Report: Fighting Depression And Improving Cognition With Omega-3 Fatty Acids - Life Extension Magazine, 10/07 - "subjects were randomly assigned to receive 1200 mg EPA plus 900 mg DHA, or placebo, for 12 weeks. At the end of the treatment period, the group receiving omega-3 fatty acids had significantly greater improvements compared with the placebo group in scores for depression, suicidality and daily stresses"
  • Omega-3 May Lower Type 1 Diabetes Risk - WebMD, 9/25/07 - "Eating a diet rich in omega-3 fats may help keep high-risk children from developing type 1 diabetes"
  • Omega-3 may boost blood vessel elasticity - study - Nutra USA, 9/21/07 - "fish oil supplementation improved large artery elasticity, compared to placebo (15.51.5 versus 12.83.7 ml.mm.Hg-1 x 10, respectively)"
  • Omega-3 Can Prevent Blindness In Premature Mice: Hospital Treatment Soon? - Science Daily, 8/18/07 - "Mice that ate omega-3 initially lost fewer blood vessels in their retinas than mice that ate omega-6, and they evinced only half as much abnormal vessel growth. Their retinas also showed lower inflammatory activity"
  • More Fish Oil, Less Vegetable Oil, Better For Your Health - Science Daily, 7/26/07 - "using more fish oil than vegetable oil in the diet decreases the formation of chemicals called prostanoids, which, when produced in excess, increase inflammation in various tissues and organs"
  • Different omega-3 may offer different colorectal protection - Nutra USA, 7/11/07 - "Increased intake of EPA was associated with a 41 per cent reduction in risk, while DHA was associated with a 37 per cent reduction in risk, comparing highest against lowest average intakes" - [Abstract]
  • Omega-3s May Help Prevent Blindness - WebMD, 6/25/07
  • Can Blindness Be Prevented Through Diet? - Science Daily, 6/24/07 - "Increasing intake of the omega-3 fatty acids DHA and EPA, found in popular fish-oil supplements, may protect against blindness resulting from abnormal blood vessel growth in the eye ... Mice on the omega-3 diet, rich in DHA (docosahexaenoic acid) and its precursor EPA (eicosapentaenoic acid), had less initial vessel loss in the retina than the omega-6-fed mice: the area with vessel loss was 40 to 50 percent smaller"
  • Omega-3 Fatty Acids May Help Slow Prostate Cancer Growth - Science Daily, 6/21/07
  • Omega-3 Fatty Acids May Lower Genetic Risk for Prostate Cancer - Medscape, 6/21/07 - "Overall, diets rich in omega-3 fatty acids reduced prostate tumor growth, slowed histopathological progression, and increased survival, the researchers write. The 12-month survival rate was 60% for mice fed a diet high in omega-3, 10% on the low–omega-3 diet, and 0% on the high–omega-6 diet. The ideal ratio of omega-6 to omega-3 fatty acids is 1:1, and mice fed diets with this ratio of fatty acids were able to delay both the formation and progression of prostate tumors and prolong their survival"
  • Omega-3 Supplements Can Help With Alzheimer's Symptoms, Study Suggests - Science Daily, 6/21/07 - "There was no observable difference in therapeutic effect between the patients receiving the omega-3 and the placebo group. However, when the researchers took into account which of the patients carried the susceptibility gene APOE4 and which did not, an appreciable difference appeared. Carriers of the gene who had received active treatment responded positively to the omega-3 as regards agitation symptoms, while non-bearers of the gene showed an improvement in depressive symptoms"
  • Omega-3s May Lower Blood Pressure - WebMD, 6/4/07 - "Participants with the highest intake of omega-3 fatty acids tended to have the lowest blood pressure"
  • Eating Fish May Preserve Eyesight - WebMD, 5/15/07
  • Higher Intake Of Fish And Vitamin D Levels Linked To Lower Risk Of Age-related Macular Disease - Science Daily, 5/14/07 - "Individuals who have higher dietary intake of foods with omega-3 fatty acids and higher fish consumption have a reduced risk of advanced age-related macular degeneration, while those with higher serum levels of vitamin D may have a reduced risk of the early stages of the disease"
  • Marine Omega-3 Fatty Acids Have Positive Effect On Muscle Mass, Study Shows - Science Daily, 5/9/07 - "In mammals, the ability to use nutrients from food and convert them into muscle proteins decreases with age. Though the exact cause of this phenomenon is still unclear, insulin resistance of aging muscle cells has been suggested as a possible answer ... omega-3 fatty acids are known to improve glucose metabolism in people and animals showing insulin resistance ... After five weeks, animals with the marine omega-3 diet showed increased sensitivity to insulin which, in turn, improved protein metabolism"
  • Preventing Breast Cancer? - Dr. Weil, 5/3/07 - "Take 2 grams of fish oil a day. High omega-3 fatty acid intake significantly reduces your risk of breast cancer"
  • Fish Oil May Help Kidney Disease Sufferers - Science Daily, 4/30/07 - "daily doses of fish oil in the form of a tablet or liquid had been shown to decrease inflammation - a common problem in people with kidney disease"
  • Fish-diabetes pollution link may boost supplements - Nutra USA, 4/13/07 - "the risk of pollutants from oily fish, such a methyl mercury, dioxins, and polychlorinated biphenols (PCBs) have led to some claims to reduce fresh fish intake, especially for pregnant women who may damage the development of their babies ... Most extracted fish oils are molecularly distilled and steam deodorised to remove contaminants ... The study, led by Professor Duk-Hee Lee observed a link between POP levels and diabetes"
  • Fish Oil: Getting to the Heart of It - Medscape, 4/12/07 - "A food-based approach to increasing intake of omega-3 fatty acids is preferable. However, for those with known CHD, the increased dose required to lower triglycerides could be as much as 4 g/day. Consuming fish 2.5 to 3 times a week would provide a combined intake of about 500 mg EPA and DHA/day.[21] It is unrealistic to think that these high daily doses could be achieved through diet alone, resulting in a requirement for supplementation"
  • Omega-3 Fatty Acid May Protect Heart - WebMD, 3/29/07 - "2.8% of those taking EPA along with statins experienced a major coronary event, compared with 3.5% of those only taking statins ... That's a 19% difference"
  • Supplement 'boosts' brain power - BBC News, 3/12/07 - "they were given two capsules a day of the VegEPA supplement, which contains an omega-3 fatty acid called EPA ... Tests done at the end of the three-month study found the children showed an increase in reading age of well over a year, their handwriting became neater and more accurate and they paid more attention in class ... In three months you might expect to see a small NAA increase ... But we saw as much growth as you would normally see in three years"
  • Omega-3 in fish oils might ease depression - USA Today, 3/6/07 - "The more DHA a person consumed, the more gray matter there was in three areas of the brain linked to mood: the amygdala, the hippocampus and the cingulate, Conklin says. Seriously depressed people tend to have less gray matter in these areas" [WebMD]
  • Balancing Omega-3 and Omega-6? - Dr. Weil, 2/22/07 - "Many nutrition experts believe that before we relied so heavily on processed foods, humans consumed omega-3 and omega-6 fatty acids in roughly equal amounts. But to our great detriment, most North Americans and Europeans now get far too much of the omega-6s and not enough of the omega-3s. This dietary imbalance may explain the rise of such diseases as asthma, coronary heart disease, many forms of cancer, autoimmunity and neurodegenerative diseases, all of which are believed to stem from inflammation in the body. The imbalance between omega-3 and omega-6 fatty acids may also contribute to obesity, depression, dyslexia, hyperactivity and even a tendency toward violence"
  • Omega-3 and joint health – more support - Nutra USA, 1/31/07 - "randomly assigned 24 patients with ankylosing spondylitis (AS), also known as Bechterews disease, to receive either high-dose (4.55 g) or low-dose (1.95 g) daily supplement of omega-3 (Epax 5500 TG) ... The patients in the high-dose group exhibited a significant decrease in disease activity according to the Bath Ankylosing Disease Activity Index, which was not seen in the low-dose group" - [Abstract]
  • Fish Oil for Moms May Benefit Babies - WebMD, 12/21/06 - "children of mothers who took fish oil supplements scored significantly higher on tests of hand-eye coordination than those who took olive oil supplements"
  • More support omega-3 may protect against colorectal cancer - Nutra USA, 11/22/06 - "A diet rich in omega-3 polyunsaturated fatty acids (PUFAs) could reduce the risk of colorectal cancer by 85 per cent"
  • Soy, Fish May Cut Cancer Risk - WebMD, 11/14/06 - "men who ate the most fish -- and that was five or more servings per week of fish -- compared to the least fish -- less than one time per week -- had a 40% lower risk of developing colorectal cancer"
  • Omega fatty acids to stop mental decline, says study - Nutra USA, 10/31/06 - "ARA plus DHA supplementation produced significant improvements in the immediate memory and attention RBANS scores (eight and five points, respectively)"
  • Omega 3 Fatty Acid Prescribing Behaviors - Medscape, 10/25/06 - "Fish oil intake, through diet or supplementation, is recommended by the AHA and can potentially reduce mortality in patients with CVD. Despite this, family physicians do not often advise increasing dietary fish intake to their patients with CVD. Improving physician awareness of fish oil's benefits on sudden death and simplifying the message should be explored further as potential strategies to increase physician recommendation of this important advice"
  • Omega-3 Fatty Acids May Slow Cognitive Decline In Some Patients With Very Mild Alzheimer's Disease - Science Daily, 10/11/06 - "For six months, 89 patients (51 women and 38 men) took 1.7 grams of docosahexaenoic acid (DHA) and .6 grams of eicosapentaenoic acid (EPA), while 85 patients (39 women and 46 men) took placebo ... among a subgroup of 32 patients with very mild cognitive impairment at the beginning of the study, those who took the fatty acids experienced less decline in six months compared with those who took placebo"
  • New Study Finds Omega-3's in Fatty Fish Can Reduce Risk of Cancer - Doctor's Guide, 9/26/06 - "At least one portion of fatty fish a week during the period (1987-2004) reduced the risk of renal cancer by 74 per cent compared with those who never ate fatty fish"
  • Fatty Fish Fight Cancer - WebMD, 9/19/06 - "Those who consistently ate lots of fatty fish over a 10-year period had a 74% lower risk of kidney cancer" - See Mega Twin EPA at Vitacosticon or iHerb.
  • Why You Need More Omega-3 Fatty Acids - Life Extension Magazine, 9/06
  • Protection for Aging Eyes - New Hope Natural Media Online, 8/31/06 - "A 40% reduction in the incidence of early age-related macular degeneration was associated with eating fish at least once a week; eating fish at least three times per week even reduced the incidence of late-stage age-related macular degeneration"
  • Fish Oils May Be Lifesavers - WebMD, 8/30/06 - "Sudden death risk dropped 6.4% with adequate omega-3 fatty acid intake, compared with 3.3% for implantable defibrillators, and less than 1% with easy access to AEDS"
  • Omega-3 Fatty Acids after Myocardial Infarction - Medscape, 8/30/06 - "OMACOR, containing 900 mg of highly purified n-3 PUFA (eicosapentaenoic acid, 46%; decosahexaenoic acid, 38%) ... The incremental number of life-years saved by OMACOR during the 4 years' follow-up was 0.054 per patient, or 54 per 1000 patients"
  • Altering Fatty Acid Levels In Diet May Reduce Prostate Cancer Growth Rate - Science Daily, 8/1/06 - "tumor cell growth rates decreased by 22 percent and PSA levels were 77 percent lower in the group receiving a healthier balance of fatty acids compared with the group that received predominantly omega-6 fatty acids"
  • Fatty Fish Helps Heart Keep Its Rhythm - WebMD, 7/28/06 - "suggests eating fish rich in omega-3 fatty acids regularly acts directly on the heart's electrical function, which regulates the heart rate and keeps it from beating too fast or too slow"
  • Fish Oil May Help Save Your Eyes - WebMD, 7/10/06 - "men with the highest fish consumption (at least two weekly servings) were 45% less likely to have AMD than those with the lowest fish consumption (less than one weekly serving)"
  • A Safer Alternative to NSAIDs? - Physician's Weekly, 7/3/06 - "omega-3 essential fatty acid (EFA) may be as effective as nonsteroidal anti-inflammatory drugs (NSAIDs) in relieving neck and lower back pain without the risk of harmful complications"
  • Omega-3s may help depressive kids - pilot study - Nutra USA, 6/23/06 - "seven out of ten children in the omega-3 group and none of the children in the placebo group had depression score reductions of 50 per cent or more"
  • Hypertriglyceridemia - Medscape, 6/1/06 - "Omega-3 fatty acids (4 g per day) will reduce triglyceride levels by 30%"
  • MIT Research Offers New Hope For Alzheimer's Patients - Science Daily, 4/27/06 - "The three compounds in the treatment cocktail - omega-3 fatty acids, uridine and choline - are all needed by brain neurons to make phospholipids, the primary component of cell membranes"
  • Does Eating Salmon Lower the Murder Rate? - New York Times, 4/16/06 - "enrolled 231 volunteers at a British prison in his study; one-half received a placebo, while the other half received fatty acids and other supplements. Over time, the antisocial behavior (as measured by assaults and other violations) of the inmates who had been given the supplements dropped by more than a third relative to their previous records"
  • Fish Oil May Help Ease Back Pain - WebMD, 4/6/06 - "88% of patients said they would keep taking fish oil supplements"
  • Fish Oil May Help Protect Against Retinal Degenerative Diseases - Science Daily, 4/6/06
  • Omega-3s could stop liver cancer cells growth - Nutra USA, 4/3/06 - "Both omega-3 fatty acids had a dose-dependent inhibitory effect"
  • Study: Benefits of Omega-3s Fishy - WebMD, 3/24/06
  • In search of those omega-3 fatty acids -  San Diego Union-Tribune, 3/7/06 - "Fish oils from supplements or dietary sources can reduce triglycerides by 20 percent to 50 percent ... Studies have used triglyceride-lowering doses of 1 to 4 grams (1,000 mg to 4,000 mg) daily"
  • In a Bad Mood? Eat Your Fish - WebMD, 3/3/06 - "People in our study who had low blood levels of omega-3 fatty acids were more likely to report mild to moderate symptoms of depression, more moodiness, and more impulsivity ... people with higher blood levels of omega-3s were found to be more agreeable"
  • Fish oils cool anger levels - Nutra USA, 1/23/06 - "The 13 patients who received the fish oil showed a clinically significant and progressive decrease in their POMS anger subscale scores"
  • Oily fish makes 'babies brainier' - BBC News, 1/20/06 - "mothers with the lowest intake of the essential fatty acid had children with a verbal IQ six points lower than the average ... Low intake of the crucial fatty acid also appeared to lead to more problems of social interactions - such as an inability to make friends"
  • Fish Oil Reduces Airway Inflammation Caused by Exercise-Induced Asthma - Doctor's Guide, 1/10/06 - "the post-exercise lung function of participants -- adults with mild-to-moderate persistent asthma -- improved by about 64% and their use of emergency inhalers decreased by 31% when they consumed a diet supplemented with fish oil, rich in omega-3 polyunsaturated fatty acids (n-3 PUFA), for three weeks"
  • Have a Daily Dose of Omega-3 - US News, 12/26/05 - "Farmed salmon are raised on fish oil pellets derived from local fish, which are often contaminated with cancer-causing PCB s. The most recent study, in the November issue of the Journal of Nutrition, reports that contaminant levels in farmed salmon from certain regions increase the risk of cancer enough to outweigh benefits"
  • Fish Oil Prevents Potentially Deadly Heart Rate Variability - Science Daily, 12/15/05 - "In this randomized controlled trial, fish oil supplementation prevented the reduction in heart rate variability associated with the same-day exposure to indoor particulate matter"
  • Fish Oil May Treat Lung Disease - WebMD, 12/12/05 - "People in the omega-3 group had two advantages. They had a significant drop in lung inflammation. They also walked farthest in the six-minute walking test"
  • Cortisol, Stress, and Health - Life Extension Magazine, 12/05 - "Supplements to reduce high cortisol levels secondary to stress ... Vitamin C: 1000-3000 mg/day ... Fish oil (omega-3 fatty acids):1-4 gm/day ... Phosphatidylserine: 300-800 mg/day ... Rhodiola rosea: 100-200 mg/day, standardized extract ... Ginseng: 100-300 mg/day, standardized extract ... Ginkgo biloba: 100-200 mg/day, standardized extract ... DHEA: 25-50 mg/day (any hormone supplementation should be monitored by your physician)"
  • Fatty Acids May Protect against Cardiovascular Disease - Doctor's Guide, 11/21/05 - "After 4.5 years of follow-up, patients taking EPA were 19% less likely to have adverse coronary events compared to controls"
  • The Nude Mouse Tale: Omega-3 Fats Save The Life Of A Terminal Cancer Patient - Science Daily, 11/14/05 - "In 2000 he was told by his doctor he had only a few months to live ... But five years later, he is still alive, and has even gained a little weight ... It was a nutritional intervention, drastically increasing the patient’s intake of omega-3 fatty acids"
  • Fish Oil Supplements Improve Lipid Risk Factors in Obese Children - Medscape, 11/14/05 - "given 3 g of a daily fish oil supplement ... After 12 weeks, the researchers found that triglyceride levels in the control group did not significantly differ from baseline. In contrast, triglyceride levels in children treated with fish oil significantly decreased. However, differences in other lipid measures were not statistically significant"
  • The Perricone Weight Loss Program - Life Extension Magazine, 11/05 - "The reason that traditional low-calorie diets fail is that they lack omega-3s, which are essential for healthy metabolism. If you follow the anti-inflammatory diet and ensure the intake of plenty of omega-3 fatty acids, you will successfully lose weight"
  • Oxidation Negates Fish Oil's Many Benefits - mercola.com, 10/31/05
  • Fish Oil Improves Endothelial Function of Healthy Subjects - Doctor's Guide, 10/27/05 - "fish oil supplementation resulted in a significant increase in endothelium-dependent brachial artery flow mediated vasodilation (EDV) and endothelium-independent nitroglycerin mediated vasodilation (EIDV)"
  • Fatty Acid Supplementation for ADHD - Medscape, 10/26/05 - "finally studies are emerging that are evaluating these possible benefits. One such study found significant improvements in reading, spelling, and behavior in a cohort of children who received dietary supplementation with omega-3 and omega-6 fatty acids.[1] In addition, studies of infants fed infant formula with fatty acid supplementation have suggested cognitive enhancement into the second year of life"
  • Dietary Fat Intake Linked To Dry Eye Syndrome In Women - Science Daily, 10/24/05 - "a high intake of omega 3 fatty acids, often referred to as a 'good' fat, commonly found in fish and walnuts, is associated with a protective effect. Conversely, a higher ratio of omega 6, a fat found in many cooking and salad oils and animal meats, compared to omega 3 in the diet, may increase the risk of dry eye syndrome"
  • Eating Fish Associated with Slower Cognitive Decline - Doctor's Guide, 10/12/05 - "Consuming fish at least once a week was associated with a 10% per year slower rate of cognitive decline in elderly people ... consumption of one omega-3 fatty acid in particular, docosahexaenoic acid (DHA), is important for memory performance in aged animals" - See DHA products at iHerb.
  • Balance of Essential Fats May Prevent Bone Loss After Menopause - Doctor's Guide, 7/13/05 - "After 12 weeks, rats with the lowest ratio of omega-6 to omega-3 fatty acids in their diet experienced significantly less bone loss than rats in the other dietary groups ... A 5-to-1 dietary ratio of omega-6 to omega-3 fatty acids led to a conservation of bone mineral content that we didn't see with a 10-to-1 ratio"
  • Omega-3, Omega-6 Fatty Acids Can Affect Bone Loss - CBS 2 Chicago, 7/12/05 - "eating foods rich in omega-3 fatty acids -- found in walnuts and salmon -- may prevent bone thinning. While excess amounts of omega-6 -- found in grains and beef -- may actually promote bone loss ... a low ratio of omega-6 to omega-3 appears to be best"
  • Getting Enough Omega-3? - Dr. Weil, 7/14/05
  • Fish Help the Heart by Fighting Inflammation - WebMD, 7/5/05 - "compared with those who said they didn't eat fish, those who ate at least 10.5 ounces of fish per week had 33% lower C-reactive protein and 33% lower tumor necrosis factor-alpha (another indicator of inflammation) levels as well as much lower levels of other signs of inflammation"
  • Omega-3 Offers Hope For New Anti-breast Cancer Drugs - Science Daily, 6/8/05 - "Compounds of Omega-3 fatty acids and propofol reduce the ability of breast cancer cells to develop into malignant tumours, inhibiting cancer cell migration by 50% and significantly reducing their metastatic activity ... Propofol is a potent anti-oxidant known to inhibit cancer cell migration by only 5-10%"
  • Modern diet may be causing depression - Nutra USA, 5/26/05 - "The finding lends itself nicely to the theory that increased omega-3 fatty acid intake may shift the balance between the two fatty acid families in the brain, since it has been demonstrated in animal studies that increased omega-3 fatty acid intake may result in decreased brain arachidonic acid"
  • Omega-3 Boosts Mood Throughout Pregnancy - Clinical Psychiatry News, 5/05 - "In a small, open-label, flexible-dose study of 15 patients using doses up to 2.8 g/day of the omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid, patients showed a mean decrease on the Edinburgh Postnatal Depression Scale (EPDS) of 39% and a mean decrease of 34% on the Hamilton Rating Scale for Depression"
  • Omega-3 Fatty Acids and Depression - Clinical Psychiatry News, 5/05 - "English investigators conducted a 12-week, double-blind, placebo-controlled trial evaluating the efficacy of EPA doses of 1,000, 2,000, or 4,000 mg/day in addition to unchanged standard treatment in 70 patients with persistent depression. The 1,000-mg group showed a significant decrease in depression as compared with placebo, but the other groups showed little evidence of efficacy ... The bulk of evidence suggests that omega-3 fatty acid supplementation is effective in treating depression in patients with low omega-3 diets"
  • Breast Cancer Protection Starts in the Womb - WebMD, 4/20/05 - "Mothers who choose foods packed with omega-3 fatty acids during pregnancy and while nursing and then feed their kids such a diet after weaning may reduce the risk of breast cancer in their daughters by nearly 90%, early research in mice indicates"
  • High-Dose Omega-3 Oils Used to Treat Non-Surgical Neck and Back Pain - Doctor's Guide, 4/20/05 - "this could be the answer to the adverse effects seen with nonsteroidal anti-inflammatory drugs (NSAIDs), including cyclooxygenase (COX)-2 inhibitors, which have been associated with potentially catastrophic adverse effects ... 88% percent said they were pleased enough with the outcomes that they planned to continue using the fish oils"
  • Fish, Soy Oil Supplements May Cut Heart Death - WebMD, 4/11/05 - "participants were randomly assigned to take fish oil supplements or soy oil pills (2 grams daily for both groups) for 11 weeks ... Both groups significantly increased their heart rate variability while taking the supplements. Greater heart rate variability reduces the risk of dangerous irregular heart beats or sudden death"
  • Fish Oil May Fight Alzheimer's Disease - WebMD, 3/22/05 - "Brain imaging showed that the high-DHA diet cut brain plaque by 40%. The largest drops were seen in brain areas vulnerable to Alzheimer's disease ... The high-DHA diet also delivered the biggest drop (70%) in levels of beta-amyloid protein in the brain, a building block of plaque"
  • The Mechanism of Action of Omega-3 Fatty Acids - Medscape, 3/16/05 - "omega-3 fatty acids play a significant role in secondary prevention post-myocardial infarction. The mechanisms through which two of these omega-3 fatty acids, eicosapentaenoic acid and docosahexanoic acid, exert their action appear to be distinct and adjuvant to the available standard secondary prevention therapies"
  • Eating Oily Fish May Reduce Inflammation - Science Daily, 3/24/05 - "This research group recently identified a new class of aspirin-triggered bioactive lipids, called resolvins, the activity of which may in part explain the beneficial effects of omega-3 fatty acids"
  • Oily fish helps cut inflammation - BBC News, 3/13/05 - "We always suggest that people with arthritis eat two or three portions of oily fish a week, or take 1,500mg fish oil capsules a day"
  • Low Fatty Acid Levels, Dementia Associated in Large Study - Clinical Psychiatry News, 3/05 - "The n-3 fatty acids are an important component of the neuronal membrane, influencing membrane fluidity and all the related functions, such as signal transduction and enzyme function ... Subjects with dementia had the lowest n-3 fatty acid plasma concentrations ... Subjects with dementia had the highest plasma concentrations of saturated fatty acids"
  • Applications of Omega-3 Fatty Acids - Medscape, 3/1/05 - "Fish saves lives, and physicians must recognize this potential life-saving treatment choice in patients with cardiovascular disease. In addition, family physicians can safely offer patients an alternative therapeutic approach for difficult-to-treat conditions such as hypertriglyceridemia and rheumatoid arthritis. For those without cardiovascular disease, including young mothers and women, it is reasonable to recommend 650 to 1000 mg of low-risk fish oils per day through dietary approaches as suggested by the National Institutes of Health working group, AHA, and the FDA—easily achieved by 1 to 2 fatty fish meals per week"
  • Antidepressant Foods - Forbes.com, 2/10/05 - "The Omega-3 diet showed results after one month, and uridine was effective as long as the rats were fed enough of it. But when given both together, within ten days the rats who were eating the good foods behaved as well as those on medications ... Uridine fuels mitochondria, and paired with the lubricating effect of the Omega-3s, helps them make more energy more efficiently"
  • Omega-3s to enter weight loss category? - Nutra USA, 1/25/05 - "The fish oil concentrates not only caused weight reduction in the mice but they also appeared to stop the animals from gaining weight when given free access to food"
  • Arthritis Patients Can Seek Natural Pain Relief - CBS Chicago, 1/15/05 - "They placed 120 patients on fish oil supplements. About 59 percent of reported decreased joint pain, and 68 percent were able to discontinue prescription drugs entirely"
  • Fish oil supplements slow ageing of brain - Nutra USA, 12/21/04 - "People who eat oily fish or take fish oil supplements score 13 per cent higher in IQ tests and are less likely to show early signs of Alzheimer’s disease ... The brains of fish oil users seemed to be faster. There was a strong relationship between mental test scores and the omega-3 content in the blood"
  • Fish Oil Could Help Crohn's Disease - WebMD, 12/10/04
  • Low-Fat Diet May Protect Against Alzheimer's - WebMD, 12/7/04 - "mice fed a low-fat diet rich in the omega-3 fatty acids found in fish and soy, produced more of a protein that helps eliminate the amyloid peptides that cause plaque in the brain"
  • The high five for hypertension - Functional Foods & Nutraceuticals, 12/04 - "Co-enzyme Q10 ... Omega-3 fatty acids ... Garlic ... L-arginine ... Calcium"
  • Alpha-Linolenic Acid Intake Inversely Associated With Cardiac Events - Medscape, 11/11/04 - "women who consumed the highest levels of ALA — defined as approximately 1.5 g per day — "had a 46% lower risk of sudden cardiac death than women who consumed the least amount of [ALA], which was just over half a gram a day ... 1.5 g equals "about two capfuls of flaxseed oil or a handful of walnuts"
  • Omega-3 Fatty Acids: Good For The Heart, And (maybe) Good For The Brain - Science Daily, 11/8/04 - "There is mounting evidence that a diet containing omega-3 fatty acids, already known to help prevent cardiovascular disease, may also prevent depression"
  • ConsumerLab.com - Omega-3 Fatty Acids (EPA and DHA) from Fish/Marine Oils review - ConsumerLab.com, 10/6/04 - "None of the products were found to contain detectable levels of mercury ... none of the products contained unsafe levels of PCBs ... none of these supplements contained unsafe levels of dioxins"
  • Fish Oil's Breast Cancer Benefits May Vary - WebMD, 9/23/04
  • Omega-3 Fatty Acids Get New Health Claim - WebMD, 9/8/04 - "The FDA now says it will allow foods and supplements containing eiscosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) omega-3 fatty acids to carry a qualified health claim that says eating the product may reduce the risk of heart disease"
  • Fish Containing N-3 Fatty Acids Reduce Risk of AF - Medscape, 7/19/04 - "Intake of fatty fish containing N-3 fatty acids reduces the risk of atrial fibrillation (AF), but fish sandwiches or fried fish are not protective"
  • Omega-3s appear to protect against prostate cancer - Nutra USA, 6/23/04 - "alpha-linolenic acid (ALA), an omega-6 fat, may raise the risk of advanced prostate cancer ... Men with the highest quintiles of EPA and DHA combined had an 11 per cent lower total prostate cancer risk and advanced prostate cancer risk was 26 per cent lower"
  • Fish Oil Prevents Deadly Irregular Heartbeats - WebMD, 4/30/04 - "If these and other trials confirm the anti-arrhythmic properties of these [omega-3 acids], fish oil may become a less toxic and more appetizing alternative to traditional anti-arrhythmic"
  • Salmon and Cod Liver Oil Contamination: Key Point - Rely on Pharmaceutical Grade Fish Oil for Your Omega-3 Fatty Acid Needs - Dr. Murray's Natural Facts, 4/21/04 - "To reduce your chances of eating salmon and other fish that is tainted with chemical toxins: ... Eat wild Alaskan salmon as opposed to farm-raised salmon ... Limit your intake of fresh water fish ... Eat smaller, young fish ... The specific product that I recommend is RxOmega-3 Factors from Natural Factors"
  • Improving Omega-3 Oils - ffnmag.com, 1/04
  • Omega-3 Fatty Acids Vital to a longer, healthier life - Life Extension Foundation, 12/03 - "While an omega-6 to omega-3 ratio of roughly 2:1 is optimal, most Americans consume far more omega-6s than omega-3s, yielding a ratio skewed at least 10:1 in favor of omega-6s. Some estimates put the ratio as high as 40:1 ... Because omega-6s break down into arachidonic acid in the body, and arachidonic acid is converted to highly inflammatory chemicals, a huge increase in the availability of arachidonic acid translates into a huge increase in the potential for inflammatory and autoimmune diseases"
  • Get Hooked On Fish - Wellness Insider, 11/25/03 - "Fish is a good source of omega 3s. Elderly individuals who consume fish three times per week can almost cut their risk in half for developing Alzheimer's disease"
  • Fish Oil May Help Elite Athletes - WebMD, 11/14/03
  • Recent Clinical Studies on Fish Oils - Dr. Murray's Natural Facts, 11/12/03
  • Fish And N-3 Fatty Acids Reduce Risk Of Alzheimer’s Disease - Life Extension Foundation, 11/03 - "A new study, from the Rush-Presbyterian, St. Lukes Medical Center, in Chicago, shows that people who consumed at least one serving of fish a week dramatically reduced their risk of Alzheimer’s disease, compared to those who rarely or never ate fish. Dietary intake of omega-3 fatty acids had a similar risk-lowering effect"
  • Diet and Exercise - Medscape, 9/9/03 - "Consumption of the omega-3 fatty acids is inversely related to the incidence of atherosclerosis and the risk of sudden death[1,2] and stroke.[3] In high doses, omega-3 fatty acids may reduce blood triglyceride levels, but in dietary amounts, they have little effect on blood lipids. Even in modest amounts, however, omega-3 fatty acids reduce platelet aggregation, impairing thrombogenesis. They may also have antiarrhythmic and plaque-stabilizing properties"
  • Inflammation Syndrome a Red-Hot Topic - Natural Foods Merchandiser, 9/03 - "What are some of the key anti-inflammatory supplements? ... At the top of the list are omega-3 fish oils, gamma-linolenic acid (GLA, an omega-6 fat that behaves more like an omega-3) and vitamin E. Several studies have shown that natural vitamin E supplements lower CRP levels by 30 percent to 50 percent"
  • The Omega Principle - WashingtonPost.com, 8/19/03 - "Omega-3s, dubbed the "happy" fats in some quarters, are under investigation for treating depression, bipolar disease, attention-deficit hyperactivity disorder, alcoholism, Alzheimer's disease and even the so-called baby blues, or postpartum depression ... there are many profound neurological disorders that are known to be caused by lipid problems ... The brain itself, is, in fact, about 60 percent fat ... while the body can manufacture saturated fat, cholesterol and even some unsaturated fat -- it is incapable of producing two of the fatty acids that are most vital ... there has been an 1,000-fold increase in [consumption of] omega-6 fatty acids ... Flooding brains and bodies with a diet rich in omega-6 fatty acids theoretically could give an unfair advantage to these molecules, allowing them to block omega-3s from getting inside cells" - See Mega Twin EPA at Vitacosticon or iHerb.
  • Eating Fish Lowers Heart Rate - WebMD, 8/12/03 - "This current study involves more than 9,700 men -- all between 50 and 59 years old -- who had no signs of heart disease. Researchers kept track of them from 1991 to 1993, documenting their heart rate, blood pressure, cholesterol, and other heart disease risk factors ... Fish eaters had the lowest heart rates. It's important information because even small reductions in heart rate can make a difference in sudden heart death"
  • Beyond the Mediterranean Diet: The Role of Omega-3 Fatty Acids in the Prevention of Coronary Heart Disease - Medscape, 8/1/03 - "The current US consumption of n-3 fatty acids is significantly below recommended levels and new American Heart Association recommendations suggest consuming at least two fish meals per week. Although additional trials are needed, the favorable safety profile and existing clinical trials suggest n-3 fatty acids should be considered a new important adjunct to existing cardiovascular prevention strategies"
  • Is Your Salmon Safe? - WebMD, 7/31/03 - "bought 10 salmon filets in grocery stores in Washington, D.C.; Portland, Ore.; and San Francisco. Lab analysis showed "high" PCB levels in seven of the 10 samples"
  • Fish Once a Week Cuts Alzheimer's Risk - WebMD, 7/21/03 - "Weekly fish eaters had a 60% lower risk of Alzheimer's than people who rarely or never ate fish ... The beneficial effects of [fatty acids] from fish may be counterbalanced by toxins ... A high antioxidant/low saturated fat diet pattern with a greater amount of fish, chicken, fruits, and vegetables and less red meat and dairy products is likely to lower the risk of AD, as well as that for heart disease and stroke ... Furthermore, B vitamin supplements, containing vitamins B12 and B6 and folic acid, lower plasma total homocysteine levels, possibly decreasing the risk of stroke, heart disease and perhaps Alzheimer's disease"
  • New Research Supports Omega-3's Benefits - Natural Foods Merchandiser, 7/03 - "Research keeps piling up to support omega-3 use for a whole host of purposes, from brain food to arrhythmia prevention. In fact, Andrew Weil, M.D., the alternative medicine promoter and guru, recommends omega-3s for no fewer than 20 conditions on his Web site"
  • Essential Fatty Acid Beneficial for Women with Personality Disorder - New Hope Natural Media, 7/3/03 - "30 women with moderately severe BPD between the ages of 18 and 40 received 500 mg twice a day of EPA or a similar looking placebo for eight weeks ... Compared with the placebo group, average aggression and depression scores decreased in the EPA treatment group by 44% and 22%, respectively ... a purified EPA product, called ethyl-eicosapentaenoic acid (E-EPA), was used in this study. This product is not yet commercially available" - See Mega Twin EPA at Vitacosticon or iHerb.
  • Pretty in Pink: Atlantic Salmon Under Fire - Natural Foods Merchandiser, 6/03 - "farm-bred salmon—which accounts for 95 percent of Atlantic salmon—is naturally gray. Wild salmon, on the other hand, derives its familiar pink hue from its diet of small crustaceans. So salmon farmers add a dye to their fish feed mix, making it indistinguishable from wild salmon and more appealing to consumers ... Many consumers, however, seek to avoid farm-raised salmon because of concerns about its exposure to antibiotics and PCBs, its higher fat content and its lower omega-3 profile. Research also suggests that canthaxanthin, the most common colorant, may cause an accumulation of pigments in the retina, resulting in impaired vision"
  • Fish May Fight Pregnancy Depression Risks - Intelihealth, 5/21/03 - "the more omega-3 fatty acids a woman consumed in seafood during the third trimester, the less likely she was to show signs of major depression at that time and for up to eight months after the birth"
  • Fish Oil Benefits Your Eyes - WebMD, 5/8/03 - "Why might fish oil protect eyes from age-related macular degeneration? One component of fish oil is docosahexaenoic acid -- DHA for short. It's one of the omega-3 fatty acids linked to other health benefits. Interestingly, DHA builds up in the eye near light-sensing nerve cells ... Those whose diets had the most fish oil were less likely to have dry eye syndrome than those whose diets had the least fish oil"
  • Dietary Omega-3 Fatty Acids May Reduce Risk of AMD - Medscape, 5/6/03 - "Dietary omega-3 fatty acids but not beta-carotene supplementation is associated with a reduced risk of age-related macular degeneration (AMD) ... omega-3 fatty acids may also reduce the risk of dry eye syndrome in women" - See Mega Twin EPA at Vitacosticon or iHerb.
  • Fatty Acids Added To Infant Formula May Cut Later Heart Disease Risks - Doctor's Guide, 5/1/03 - "Several studies have reported lower blood pressure in adults whose diet was supplemented with omega 3 fatty acids, but no published studies have looked at the effect of LCPUFA supplementation on blood pressure in children ... The LCPUFA group had significantly lower mean blood pressure: mean difference -3.0 mm Hg, and mean difference of -3.5 mm Hg diastolic"
  • Fortified Formulas Promote Healthy Heart - WebMD, 5/1/03
  • Anti-Inflammatory Diet Plus Fish Oil Effective for Rheumatoid Arthritis - New Hope Natural Media, 5/1/03 - "An anti-inflammatory diet and fish oil supplements are both helpful for people with rheumatoid arthritis (RA), but combining them has an even greater effect ... The anti-inflammatory diet improved joint pain, swelling, and overall ability to function by 14%, while the Western diet did not improve symptoms or functioning. Benefits were observed with the addition of fish oil, bringing total improvement to 17% in those eating a Western diet and 37% in those eating the anti-inflammatory diet. Furthermore, the need for anti-inflammatory medications was significantly reduced for those receiving fish oil on both diets, although the group eating the anti-inflammatory diet had greater medication reduction. Medication usage increased for those on the Western diet plus placebo"
  • Eating Fish Lowers Heart Disease Risk in Women With Diabetes - WebMD, 3/31/03 - "Women with type 2 diabetes who ate fish once a week were 40% less likely to develop heart disease than those who rarely ate it, and eating fish almost every day was associated with a two-thirds reduction in risk ... It is believed that omega-3 fatty acids abundant in the fat of many fish reduces the risk of heart disease by lowering triglyceride levels, improving blood vessel function, and reducing blood-clot formation"
  • Lipid Benefits With Monounsaturated-Fatty-Acids Diet In Healthy People - Doctor's Guide, 3/14/03 - "A moderate supplementation of long-chain n-3 fatty acids in healthy individuals reduces both fasting and post-prandial triacylglycerol concentrations but increases LDL cholesterol, irrespective of the type of diet"
  • New Fish Oil Guidelines Endorse Use of Supplements - Clinical Psychiatry News, 1/03 - "the American Heart Association (AHA) has recommended that these patients [documented coronary heart disease] consume about 1g of omega-3 fatty acids per day ... In a major departure, the AHA also said, for the first time, that a recommended nutrient could alternatively be consumed as a supplement"
  • The Importance of Pharmaceutical Grade Marine Lipids - Dr. Murray's Newsletter, 1/22/03 - "A diet that is deficient in omega-3 fatty acids, particularly EPA and DHA, results in altered cell membranes. Without a healthy membrane, cells lose their ability to hold water, vital nutrients, and electrolytes. They also lose their ability to communicate with other cells and be controlled by regulating hormones. They simply do not function properly. Cell membrane dysfunction is a critical factor in the development of virtually every chronic disease, especially cancer, diabetes, arthritis, and heart disease ...RxOmega-3 Factors from Natural Factors is an example of this revolutionary new source of long-chain fatty acids"
  • Fish Oil Soothes Personality Disorder - WebMD, 1/17/03 - "a new study shows daily fish oil supplementation can significantly reduce their symptoms without the negative side effects associated with other treatments" - See Mega Twin EPA at Vitacosticon or iHerb.
  • BPD Patients Respond To Omega-3 Fatty Acids - Psychiatric News, 1/17/03 - "recruited women for their study through ads placed in Boston newspapers. The ads asked questions such as, "Are you extremely moody? Do you often feel out of control? Are your relationships painful and difficult?" ... In an eight-week study period, 20 of the 30 subjects received daily two 500 mg capsules of an omega-3 fatty acid called E-EPA (ethyl-eicosapentaenoic acid). The remaining 10 subjects received a placebo daily—two capsules containing mineral oil ... They found that while depression and aggression levels had declined in the placebo group from the start of the study to the end, they had dropped even more so in the treatment group ... the omega-3 fatty acid used—E-EPA—"may be a safe and effective form of monotherapy for women with moderately severe borderline personality disorder." ... Perhaps it works, at least in part, through its ability to lead to [cell] membrane stabilization [in the brain] ... the brain is made up of at least 60 percent lipids"
  • E-EPA Helpful in Borderline Personality Disorder - Medscape, 1/16/03
  • Fatty Acid Effective against Depression - New Hope Natural Media, 1/9/03 - "E-EPA is a chemically modified form of EPA ... the best results were achieved with the smallest amount of E-EPA tested ... The authors of the study speculated that taking too much E-EPA might cause an imbalance between the two major classes of essential fatty acids: the omega-3 class (which includes EPA) and the omega-6 class (which includes linoleic and arachidonic acids ... E-EPA is not widely available at the present time"
  • Combating Skin Aging - Life Extension Magazine, 1/03 - "The oral ingestion of fish, flax or perilla oil provides abundant quantities of the omega-3 fatty acids that are so beneficial to the health and appearance of the skin"
  • Eicosapentaenoic Acid Enhances Vasodilatation in Coronary Artery Disease Patients - Doctor's Guide, 12/30/02 - "The omega-3 polyunsaturated fatty acid EPA has been shown to improve endothelium-dependent vasodilatation in atherosclerotic arteries"
  • Study in 43,000 men touts benefits of even a little fish - USA Today, 12/24/02 - "Men who ate about 3 to 5 ounces of fish one to three times a month were 43% less likely to have a stroke during 12 years of follow-up ... Omega-3 fatty acids, found in most fish, have been shown to lower levels of blood fats linked to cardiovascular disease and to help keep blood from clotting"
  • Evidence-based Products - Functional Foods & Nutraceuticals, 12/02 - "3g EPA/d and 3g DHA/d (ROPUFA) increased systemic arterial compliance in 38 dyslipidemic men and women, resulting in reduced pulse pressure and total vascular resistance ... Results showed that ROPUFA increased SAC—36 per cent with EPA and 27 per cent with DHA—compared with placebo"
  • Heart Risks Tied Directly To Mercury In Nine-Country Study - Doctor's Guide, 12/2/02 - "High mercury content in some fish may diminish the cardioprotective effects associated with consumption of omega-three fatty acids fish ... While the toenail mercury level was directly associated with risk of myocardial infarction, the fish oil level was inversely associated with this risk"
  • Losing Out on Omega-3s? - Dr. Weil, 11/26/02 - "Omega-3s can be destroyed by air, light and heat, which is why the less exposure and processing that fish undergo between being caught and ending up on your plate, the better"
  • Fatty acids from fish can ward off heart attacks - Intelihealth, 11/19/02 - "Studies now suggest that components of fish oil, called omega-3 fatty acids, can save the lives of people with heart disease ... The heart association also cited recent research indicating that even people with healthy hearts can benefit from a diet rich in such fish as salmon, bluefish, Arctic char, mackerel and swordfish ... fish can reduce a man's risk of dying from a heart attack by 80% ... omega-3 fatty acids can cut a woman's risk of death by heart attack by 33% ... Fatty fish can contain significant levels of mercury"
  • Those With Heart Disease Should Eat Fish - Intelihealth, 11/19/02 - "Various studies of fish or supplements showed a 4 percent to 30 percent reduction in triglycerides, but a doctor's care is advised because large doses can present a risk of bleeding in some people ... People can get the recommended 1 gram per day of DHA and EPA comb