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Home > Health Conditions > Cataracts.

Cataracts

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  • Healthy Vitamin C Amount Might Prevent Cataracts - WebMD, 3/24/16 - "The new study included more than 1,000 pairs of 60-year-old British female twins. The researchers found that those who took in high amounts of vitamin C in their diet had a one-third lower risk of cataract over 10 years ... Hammond's team now believes that a person's genetics probably account for 35 percent of the risk of cataract progression, while diet and other environmental factors may account for the other 65 percent"
  • Vitamin E and risk of age-related cataract: a meta-analysis - Public Health Nutr. 2015 Jan 16 - "age-related cataract (ARC) ... Dietary vitamin E intake, dietary and supplemental vitamin E intake, and high serum tocopherol levels were significantly associated with decreased risk of ARC, the pooled relative risk was 0.73 (95 % CI 0.58, 0.92), 0.86 (95 % CI 0.75, 0.99) and 0.77 (95 % CI 0.66, 0.91), respectively. Supplemental vitamin E intake was non-significantly associated with ARC risk (relative risk=0.92; 95 % CI 0.78, 1.07). The findings from dose-response analysis showed evidence of a non-linear association between dietary vitamin E intake and ARC. The risk of ARC decreased with dietary vitamin E intake from 7 mg/d (relative risk=0.94; 95 % CI 0.90, 0.97)" - See Jarrow FamilE (contains all eight members of the vitamin E family, includes Tocomin) at Amazon.com.
  • Grape seed extract and zinc containing nutritional food supplement prevents onset and progression of age-related cataract in wistar rats - J Nutr Health Aging. 2014;18(5):524-30 - "In the group treated with combined formulation of grape seed extract and Zincovit tablets, the formation of cataract was significantly prevented. In the normal and selenite induced senile cataract control group, the levels of lens oxidative stress markers, G6PD and ATP were substantially lower than in the grape seed extract with Zincovit tablets treated group" - See grape seed extract at Amazon.com and Health Aid Zincovit - C (Zinc, Vit C & Propolis) - Blister Pack 60 Tablets.
  • The effect of multivitamin/mineral supplements on age-related cataracts: a systematic review and meta-analysis - Nutrients. 2014 Feb 28;6(3):931-49 - "we searched multiple databases to identify relevant studies including both cohort studies and randomized controlled trials (RCTs) ... Pooled results from the cohort studies indicated that multivitamin/mineral supplements have a significant beneficial effect in decreasing the risk of nuclear cataracts (RR: 0.73; 95% CI: 0.64-0.82), cortical cataracts (RR: 0.81; 95% CI: 0.68-0.94), and any cataracts (RR: 0.66; 95% CI: 0.39-0.93)" - See Garden of Life, Vitamin Code, 50 & Wiser Men at Amazon.com and Garden of Life, Vitamin Code, 50 & Wiser Women at Amazon.com.
  • Long-term daily multivitamin supplement use decreases cataract risk in men, study finds - Science Daily, 2/20/14 - "researchers based at Brigham and Women's Hospital and Harvard Medical School -- as part of the Physicians' Health Study II (PHS II) -- conducted a randomized, double-blind study from 1997 to 2011 of 14,641 U.S. male doctors age 50 and older. Half took a common daily multivitamin, as well as vitamin C, vitamin E and beta carotene supplement ... The researchers found that in the placebo group 945 cases of cataract developed, which were self-reported and confirmed by medical records, while only 872 cases of cataract developed in the multivitamin group, representing a 9 percent decrease in risk"
  • Association between Lutein and Zeaxanthin Status and the Risk of Cataract: A Meta-Analysis - Nutrients. 2014 Jan 22;6(1):452-65 - "MEDLINE, EMBASE, ISI and Cochrane Library were searched to identify relevant studies up to April 2013 ... There were significant inverse associations between nuclear cataract and blood lutein and zeaxanthin concentrations, with the pooled RRs ranging from 0.63 (95% confidence interval (CI): 0.49, 0.77) for zeaxanthin to 0.73 (95% CI: 0.59, 0.87) for lutein" - See carotenoids at Amazon.com.
  • Daily Multivitamin May Lower Risk for Cataracts - Medscape, 12/2/13 - "The eye disease component of PHS II involved 11,497 male physicians randomly assigned to take a daily multivitamin (Centrum Silver, Pfizer) (n = 5736) or placebo (n = 5761) in the cataract part of the study, and 14,233 men randomly assigned to a multivitamin (n = 7111) or placebo (n = 7122) in the AMD part of the study. Study participants reported no cataract or AMD incidence at baseline ... The researchers found a 9% lower risk for cataract among participants in the multivitamin group compared with the placebo" - Note:  My opinion is that Centrum is one of those supplement designed by an accountant.  Examples, the dl-Alpha form of vitamin E, the least absorbable for of copper, etc.
  • Preventative Effects of Ginkgo biloba Extract (EGb761) on High Glucose-Cultured Opacity of Rat Lens - Phytother Res. 2013 Sep - "Diabetic cataract is one of the earliest secondary complications of diabetes ... we examined the protective effects of Ginkgo biloba extract (EGb761) on rat lenses cultured in high-glucose conditions ... The cultured rat lenses were divided into six groups: normal group, high-glucose group, high glucose plus low, medium, and high concentrations of EGb761 groups, and a high glucose plus bendazac lysine group ... Compared with the levels in the high glucose group, EGb761 decreased the intensity of oxidative stress, decreased aldose reductase activation and the level of advanced glycosylation end products, and suppress the transforming growth factor-β2 or Smad pathway activation, further increase the expression of E-cadherin and decrease α-smooth muscle actin, and therefore, prevents the pathological changes of high glucose-induced lens epithelial cells and ameliorated lens opacity. These results suggest that EGb761 has protective effects on several pharmacological targets in the progress of diabetic cataract and is a potential drug for the prevention of diabetic cataract" - See Ginkgo biloba at Amazon.com.
  • Association of blood antioxidants and vitamins with risk of age-related cataract: a meta-analysis of observational studies - Am J Clin Nutr. 2013 Jul 10 - "searched PubMed, EMBASE, and the Web of Science for relevant studies ... A pooled estimate showed vitamin E (OR: 0.75; 95% CI: 0.58, 0.96), α-carotene (OR: 0.72; 95% CI: 0.59, 0.88), lutein (OR: 0.75; 95% CI: 0.65, 0.87), and zeaxanthin (OR: 0.70; 95% CI: 0.60, 0.82) were inversely associated with age-related cataract. Vitamins A (OR: 0.69; 95% CI: 0.58, 0.83) and C (OR: 0.67; 95% CI: 0.57, 0.78) were inversely associated with age-related cataract in Asian populations but not in Western populations. β-Carotene (OR: 0.90; 95% CI: 0.78, 1.05), lycopene (OR: 0.86; 95% CI: 0.65, 1.15), and β-cryptoxanthin (OR: 0.83; 95% CI: 0.68, 1.02) had no significant association with risk of cataract" - See Jarrow Formulas, CarotenALL at Amazon.com and Jarrow FamilE (contains all eight members of the vitamin E family, includes Tocomin) at Amazon.com.
  • Nutrients Promote Eye Health in Aging, Says Panel - Medscape, 4/17/12 - "They pointed out that many multivitamin supplements do not contain nutrients important for eye health, including lutein, zeaxanthin, and long-chain omega-3 fatty acids. "Taking a supplement specifically designed for eye health that contains these key nutrients, in addition to a general nutritional supplement, may therefore be a better approach to filling dietary shortfalls,""
  • Plasma lutein and zeaxanthin and the risk of age-related nuclear cataract among the elderly Finnish population - Br J Nutr. 2011 Oct 18:1-7 - "After adjustment for age, examination year, sex, BMI, smoking, alcohol consumption, serum LDL-cholesterol, serum HDL-cholesterol, years of education, use of oral corticosteroids, history of diabetes and history of hypertension with current use of antihypertensive medication, subjects in the highest tertiles of plasma concentrations of lutein and zeaxanthin had 42 and 41 % lower risks of nuclear cataract, respectively, compared with those in the lowest tertiles (relative risk (RR) = 0.58, 95 % CI 0.35, 0.98; P = 0.041 for lutein and RR = 0.59, 95 % CI 0.35, 0.99; P = 0.046 for zeaxanthin)" - See Jarrow Formulas, CarotenALL at Amazon.com.
  • Diet, vegetarianism, and cataract risk - Am J Clin Nutr. 2011 Mar 23 - "There was a strong relation between cataract risk and diet group, with a progressive decrease in risk of cataract in high meat eaters to low meat eaters, fish eaters (participants who ate fish but not meat), vegetarians, and vegans. After multivariable adjustment, incidence rate ratios (95% CIs) for moderate meat eaters (50-99 g meat/d), low meat eaters (<50 g meat/d), fish eaters, vegetarians, and vegans compared with high-meat eaters (≥100 g meat/d) were 0.96 (0.84, 1.11), 0.85 (0.72, 0.99), 0.79 (0.65, 0.97), 0.70 (0.58, 0.84), and 0.60 (0.38, 0.96), respectively (P < 0.001 for heterogeneity). Associations between cataract risk and intakes of selected nutrients and foods generally reflected the strong association with diet group"
  • New Evidence That Popular Dietary Supplement May Help Prevent, Treat Cataracts - Science Daily, 7/15/09 - "The scientists exposed tissue cultures of healthy rat lenses to either guanidine — a substance known to form cataracts — or a combination of guanidine and carnosine. The guanidine lenses became completely cloudy, while the guanidine/carnosine lenses developed 50 to 60 percent less cloudiness. Carnosine also restored most of the clarity to clouded lenses. The results demonstrate the potential of using carnosine for preventing and treating cataracts, the scientists say" - See l-carnosine products at iHerb.
  • Eye Drops for Cataracts? - Dr. Weil, 6/26/09
  • Vision: Antioxidants May Cut Cataracts - New York Times, 2/12/08 - "Compared with the one-fifth of women who consumed the least antioxidants, the one-fifth who consumed the most reduced their risk for cataracts by 14 percent with vitamin E and 18 percent with lutein"
  • Dietary carotenoids, vitamins C and e, and risk of cataract in women: a prospective study - Arch Ophthalmol. 2008 Jan;126(1):102-9 - "In these prospective observational data from a large cohort of female health professionals, higher dietary intakes of lutein/zeaxanthin and vitamin E from food and supplements were associated with significantly decreased risks of cataract"
  • Eat Your Leafy Vegetables To Decreased Your Risk Of Cataracts - Science Daily, 1/14/08 - "When the participants were split into five groups based on the amount of lutein and zeaxanthin they consumed, those in the group who consumed the most (about 6,716 micrograms per day) had an 18 percent lower chance of developing cataracts than those who consumed the least (1,177 micrograms per day). The one-fifth who consumed the most vitamin E from food and supplements--about 262.4 milligrams per day--were 14 percent less likely than the one-fifth who got the least (4.4 milligrams per day)"
  • Diets With High Glycemic Index May Raise Cataract Risk - Medscape, 11/30/07 - "Glycemic load, a food's glycemic index multiplied by the total available carbohydrate content, was used to gauge both carbohydrate quantity and quality ... each standard deviation increase in dietary glycemic index was associated with a 19% increase in the risk of cortical cataract. Subjects in the highest glycemic index quartile were 77% more likely to develop cataract than those in the lowest quartile"
  • Carbohydrate nutrition, glycemic index, and the 10-y incidence of cataract - Am J Clin Nutr. 2007 Nov;86(5):1502-8 - "poorer dietary carbohydrate quality, reflected by high GI, predicted incident cortical cataract"
  • Nutritional Strategies for Preventing Age-Related Vision Loss - Life Extension Magazine, 5/06
  • Study: Fruits, Veggies May Help Avoid Cataracts - WebMD, 6/17/05 - "Over 10 years, the group had a total of 2,067 cataract cases. The women who ate the most fruits and vegetables were 10% to 15% less likely to be in that group"
  • Fruit and vegetable intake and the risk of cataract in women - Am J Clin Nutr. 2005 Jun;81(6):1417-1422 - "Compared with women in the lowest quintile of fruit and vegetable intake, women with higher intakes had modest 10-15% reduced risks of cataract"
  • Moderate Red Wine Drinking Reduces Risk for Cataract - Medscape, 5/5/05 - "Five-year incidence of cataract was 22% in drinkers and 32.2% in nondrinkers. Based on alcohol consumption, cataracts occurred in 23% of beer drinkers, 19% of spirit drinkers, and 13% of wine drinkers"
  • Tea May Help Prevent Diabetes And Cataracts - Science Daily, 4/19/05 - "At levels that would be equivalent to less than five cups of tea per day for a human, both teas significantly inhibited cataract formation relative to a control group which did not get tea, they say. The researchers found that both teas decreased glucose levels, which in turn affects other biochemical pathways that accelerate diabetic complications such as cataracts" - See iHerb or Vitacosticon green tea products.  My favorite is Jarrow Green Tea at Amazon.com.
  • Eat Spinach, Prevent Cataracts? - WebMD, 12/3/04 - "Our results are the first to provide physical evidence suggesting that lutein and zeaxanthin decrease damage caused by ultraviolet radiation"
  • Lutein for Cataract Sufferers - New Hope Natural Media, 3/13/03 - "15 individuals with age-related cataracts were randomly assigned to receive either 15 mg of lutein, 100 IU of vitamin E, or a placebo three times per week for up to two years. Visual acuity improved significantly in the lutein group, whereas no change was seen in the vitamin E and placebo groups"
  • Oxidative Stress Linked to Cataract Formation in Diabetics - Doctor's Guide, 1/16/03 - "Whole blood glutathione levels and erythrocyte superoxide dismutase activities were lower, while plasma levels of thiobarbituric acid reactive substances were higher in patients with cataracts compared to controls ... The authors suggest that their findings underscore the vital role of glutathione as a lens antioxidant" - Related Article:
    • Getting More Glutathione? - Dr. Weil, 8/29/02 - "To my knowledge, the only supplement that effectively raises glutathione levels in the body is N-acetyl-L-cysteine (NAC). My colleague Kathleen Johnson, a dietician here at the Program in Integrative Medicine, tells me that other glutathione supplements are ineffective because they’re digested before they can get into the bloodstream" - See iHerb or Vitacosticon NAC products.
  • Antioxidants Shrink Cataract Risk By More Than Half - Intelihealth, 2/28/02
  • The Aging Eye ...and what can be done to protect it - Life Extension Magazine, 2/02
  • Vitamin C Reduces The Odds Of Developing Early-Onset Cataract - Doctor's Guide, 2/22/02 - "A significant interaction was observed between age, vitamin C intake, and the prevalence of cataracts. For women younger than 60 years, the consumption of vitamin C >/= 362 mg/day was associated with a 57 percent lower risk of developing cortical opacities, and the use of vitamin C supplements for at least 10 years was associated with a 60 percent reduction in the risk of cataracts, when compared to no supplement use ... the incidence of posterior subcapsulary cataracts was considerably lower in women who had never smoked and who had high intakes of folate and carotenoids"
  • What constitutes a glycation-reduced diet? - Life Extension Magazine, 11/01 - "Glycation of proteins has been shown to play a prominent role in the development of many diseases related to diabetes, atherosclerosis and cataract formation. Glycation also occurs as a result of general aging. A glycation reduction diet would be one that is low in simple sugars and carbohydrates. There are also certain supplements that help reduce glycation, such as carnosine. Carnosine is the most effective natural anti-glycating agent ... Other supplements include alpha lipoic acid, chromium picolinate and calcium pyruvate ... Taking antioxidants can help [with cataracts]. These supplements include melatonin, N-acetyl-cysteine (NAC), vitamin C and bioflavonoids"
  • Vitamins and Vision, Lots of "C" May Help You See Later in Life- WebMD, 12/11/00 - "Risk of cataracts was 60% lower among people who took multivitamins or any supplement containing vitamin C or E for more than 10 years."
  • Long-Term Vitamin C Use Cuts Cataract Risk In Older Women - Doctor's Guide, 10/9/97 - "taking vitamin C supplements for more than 10 years lowers the risk of lens opacities that can lead to cataract surgery in older women"

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