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Anti-aging Research > IP-6
Inositol Hexaphosphate (IP-6)
Note: IP-6 was one of the supplements I took when
they told me I only had a small chance of survival from neck cancer.
Click here for the full story. I
still take it.
News & Research:
- Inositol, depression
and mania - biopsychiatry.com - "Inositol is a
simple polyol precursor in a second messenger system important in brain
myo-insitol, the natural isomer, which has been found to be therapeutically
effective in depression, panic disorder, and obsessive-compulsive disorder
in double-blind controlled trials"
Omega-3 Fatty Acids
Plus Inositol Promising in Pediatric BPD - Medscape, 6/26/14 -
"The effects that we saw with these products,
particularly the combination of high EPA omega-3 fatty acids plus inositol,
were comparable to the effects that we are accustomed to seeing with more
toxic drugs. It was quite surprising and quite impressive ... The small
study included 24 children aged 6 to 12 years ... randomly assigned to
receive either monotherapy with EPA/DHA (docosahexaenoic acid) omega-3 fatty
acids (3000 mg) plus placebo (n = 7), inositol (2000 mg for children
weighing 25 kg or more; 80 mg/kg for children weighing less than 25 kg) plus
placebo (n = 7), or the combined active treatment of omega-3 fatty acids and
inositol ... At the end of 12 weeks, the children who received the combined
treatment of omega-3 fatty acids and inositol showed significantly greater
improvement on the Young Mania Rating Scale (YMRS) than those treated with
inositol (P = .021) and omega-3 fatty acids (P = .046) alone" - See
fish oil supplements at Amazon.com
inositol at Amazon.com.
Fiber Diet Prevents Prostate Cancer Progression, Study Shows - Science
Daily, 1/9/13 - "The rate of prostate cancer
occurrence in Asian cultures is similar to the rate in Western cultures, but
in the West, prostate cancer tends to progress, whereas in Asian cultures it
does not. Why? .... the answer may be a high-fiber diet ... The study
compared mice fed with of inositol hexaphosphate (IP6), a major component of
high-fiber diets, to control mice that were not. Then the study used MRI to
monitor the progression of prostate cancer in these models ... The study's
results were really rather profound. We saw dramatically reduced tumor
volumes, primarily due to the anti-angiogenic effects of IP6 ... Basically,
feeding with the active ingredient of a high-fiber diet kept prostate tumors
from making the new blood vessels they needed to supply themselves with
energy" - See
IP-6 products at Amazon.com.
Postmenopausal Women With Metabolic Syndromed - Medscape, 2/7/11 -
"In conclusion, this first report concerning
myo-inositol supplementation for 6 months in postmenopausal women affected
by metabolic syndrome demonstrated that it may improve some of the metabolic
features of the syndrome such as carbohydrate metabolism, lipid profile, and
blood pressure. Further studies and a longer time of treatment are needed to
determine if the improvement in risk markers might provide a decrease in
cardiovascular morbidity among these women"
Antioxidants Could Provide All-purpose Radiation Protection - Science
Daily, 11/5/07 - "Inositol and inositol
hexaphosphate (IP6) protected both human skin cells and a skin cancer-prone
mouse from exposure to ultraviolet B (UVB) radiation, the damaging radiation
found in sunlight ... Twenty-three percent of treated mice developed tumors,
compared to 51 percent of untreated, or control mice, which developed
tumors. Moreover, the mice in the treated group that did develop cancer had
only half as many tumors as the control mice" - See
IP-6 products at Amazon.com.
The Wizard is Oz - Life Extension Magazine, 11/01 -
"Best-selling author and nutritional guru to the
rich and famous, Oz Garcia is singing the praises of the Life Extension
Foundation and its products in his newest book,
Healthy High Tech Body, published in September 2001 ... Supplements at
the top of Garcia's list of recommendations ...
DHA ... NADH ...
Alpah Lipoic Acid
... Acetyl-L-Carnitine ... An expanded list of his
recommendations includes lycopene,
gamma tocopherol, vinpocetine, SAMe,
folic acid, carnosine,
glutathione, DMAE, Huperzine A,
arginine pyroglutamate, IP-6, bioflavonoid
grape skin/seed extracts"
Scientists Find Model to Repair DNA - Nutrition Science News, 10/01
Natural Sugar-Phosphate Compound Shows Promise as Cancer Treatment -
University of Maryland Medicine -
"In a study of human liver cancer cells treated with
inositol hexaphosphate (IP6) and transplanted into mice ... IP6 slowed or
stopped the growth of liver cancer cells and shrank existing tumors three-
- Natural Sugar-Phosphate
Compound Shows Promise In Cancer - Doctor's Guide, 3/30/98 -
"What if a common, naturally occurring substance could shrink tumours, stop
their growth, even make cancer cells normal again? A University of Maryland
School of Medicine researcher is finding that it can."
- How We Die -
Colorado Futurescience, Inc
of myo-inositol supplementation in postmenopausal women with metabolic
syndrome: a perspective, randomized, placebo-controlled study -
Menopause. 2010 Aug 31 -
"Myo-inositol plus diet improved systolic and
diastolic blood pressure, HOMA index, cholesterol, and triglyceride serum
levels with highly significant differences, compared with the groups treated
only with diet and placebo. In the group treated with myo-inositol, a
decrease in diastolic blood pressure (-11%), HOMA index (-75%), and serum
triglycerides (-20%) and an improvement in high-density lipoprotein
cholesterol (22%) were shown ... CONCLUSIONS: Supplementation with
myo-inositol may be considered a reliable option in the treatment of
metabolic syndrome in postmenopausal women" - Note: See
http://en.wikipedia.org/wiki/Inositol which claim myo-inositol and
inositol are the same. See
myo inositol at Amazon.com.
Double-Blind Studies to Evaluate the Cognitive Effects of Inositol-Stabilized
Arginine Silicate in Healthy Physically Active Adults - Nutrients. 2016 Nov
18;8(11) - "Inositol-stabilized arginine silicate (ASI;
Nitrosigine®) has been validated to increase levels of arginine, silicon and
nitric oxide production. To evaluate potential enhancement of mental focus and
clarity, ASI (1500 mg/day) was tested in two double-blind placebo-controlled
crossover (DBPC-X) studies using the Trail Making Test (TMT, Parts A and B) ...
These findings show that ASI significantly improved the ability to perform
complex cognitive tests requiring mental flexibility, processing speed and
executive functioning" - See Nitrosigine®
Hexaphosphate and Inositol Inhibit Colorectal Cancer Metastasis to the Liver in
BALB/c Mice - Nutrients. 2016 May 12;8(5) -
"Inositol hexaphosphate (IP6) and inositol (Ins), naturally occurring
carbohydrates present in most mammals and plants, inhibit the growth of numerous
cancers both in vitro and in vivo ... the tumor weights of liver metastases and
the tumor inhibition rates were reduced in the experimental groups compared to
the control group and that treatment with the combination of IP6 and Ins
resulted in greater inhibition of tumor growth than treatment with either
compound alone" - See
IP-6 products at Amazon.com.
an Early Event in the Modulation of Gene Expression by Inositol Hexaphosphate in
Ethylnitrosourea Exposed Mouse Lungs - Nutr Cancer. 2010 Dec 13:1-11 -
"study indicates the possible role of epigenetics at
the early stage of tumor development and in the regulation of gene expression by
IP6 before the onset of ENU-induced lung tumors"
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