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Home > Anti-aging Research > IP-6

Inositol Hexaphosphate (IP-6)

Note:  IP-6 was one of the supplements I took when they told me I only had a small chance of survival from neck cancer.  Click here for the full story.  I still take it.

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News & Research:

  • Inositol, depression and mania - biopsychiatry.com - "Inositol is a simple polyol precursor in a second messenger system important in brain myo-insitol, the natural isomer, which has been found to be therapeutically effective in depression, panic disorder, and obsessive-compulsive disorder in double-blind controlled trials"
  • Omega-3 Fatty Acids Plus Inositol Promising in Pediatric BPD - Medscape, 6/26/14 - "The effects that we saw with these products, particularly the combination of high EPA omega-3 fatty acids plus inositol, were comparable to the effects that we are accustomed to seeing with more toxic drugs. It was quite surprising and quite impressive ... The small study included 24 children aged 6 to 12 years ... randomly assigned to receive either monotherapy with EPA/DHA (docosahexaenoic acid) omega-3 fatty acids (3000 mg) plus placebo (n = 7), inositol (2000 mg for children weighing 25 kg or more; 80 mg/kg for children weighing less than 25 kg) plus placebo (n = 7), or the combined active treatment of omega-3 fatty acids and inositol ... At the end of 12 weeks, the children who received the combined treatment of omega-3 fatty acids and inositol showed significantly greater improvement on the Young Mania Rating Scale (YMRS) than those treated with inositol (P = .021) and omega-3 fatty acids (P = .046) alone" - See fish oil supplements at Amazon.com and inositol at Amazon.com.
  • High Fiber Diet Prevents Prostate Cancer Progression, Study Shows - Science Daily, 1/9/13 - "The rate of prostate cancer occurrence in Asian cultures is similar to the rate in Western cultures, but in the West, prostate cancer tends to progress, whereas in Asian cultures it does not. Why? .... the answer may be a high-fiber diet ... The study compared mice fed with of inositol hexaphosphate (IP6), a major component of high-fiber diets, to control mice that were not. Then the study used MRI to monitor the progression of prostate cancer in these models ... The study's results were really rather profound. We saw dramatically reduced tumor volumes, primarily due to the anti-angiogenic effects of IP6 ... Basically, feeding with the active ingredient of a high-fiber diet kept prostate tumors from making the new blood vessels they needed to supply themselves with energy" - See IP-6 products at Amazon.com.
  • Myo-inositol in Postmenopausal Women With Metabolic Syndromed - Medscape, 2/7/11 - "In conclusion, this first report concerning myo-inositol supplementation for 6 months in postmenopausal women affected by metabolic syndrome demonstrated that it may improve some of the metabolic features of the syndrome such as carbohydrate metabolism, lipid profile, and blood pressure. Further studies and a longer time of treatment are needed to determine if the improvement in risk markers might provide a decrease in cardiovascular morbidity among these women"
  • Antioxidants Could Provide All-purpose Radiation Protection - Science Daily, 11/5/07 - "Inositol and inositol hexaphosphate (IP6) protected both human skin cells and a skin cancer-prone mouse from exposure to ultraviolet B (UVB) radiation, the damaging radiation found in sunlight ... Twenty-three percent of treated mice developed tumors, compared to 51 percent of untreated, or control mice, which developed tumors. Moreover, the mice in the treated group that did develop cancer had only half as many tumors as the control mice" - See IP-6 products at Amazon.com.
  • The Wizard is Oz - Life Extension Magazine, 11/01 - "Best-selling author and nutritional guru to the rich and famous, Oz Garcia is singing the praises of the Life Extension Foundation and its products in his newest book, The Healthy High Tech Body, published in September 2001 ... Supplements at the top of Garcia's list of recommendations ... DHA ... NADH ... Alpah Lipoic Acid ... Acetyl-L-Carnitine ... An expanded list of his recommendations includes lycopene, gamma tocopherol, vinpocetine, SAMe, folic acid, carnosine, glutathione, DMAE, Huperzine A, probiotics, MSM, secretagogues, arginine pyroglutamate, IP-6, bioflavonoid formulas and grape skin/seed extracts"
  • Scientists Find Model to Repair DNA - Nutrition Science News, 10/01
  • Natural Sugar-Phosphate Compound Shows Promise as Cancer Treatment - University of Maryland Medicine - "In a study of human liver cancer cells treated with inositol hexaphosphate (IP6) and transplanted into mice ... IP6 slowed or stopped the growth of liver cancer cells and shrank existing tumors three- to four-fold"
  • Natural Sugar-Phosphate Compound Shows Promise In Cancer - Doctor's Guide, 3/30/98 - "What if a common, naturally occurring substance could shrink tumours, stop their growth, even make cancer cells normal again? A University of Maryland School of Medicine researcher is finding that it can."
  • How We Die - Colorado Futurescience, Inc
  • Effects of myo-inositol supplementation in postmenopausal women with metabolic syndrome: a perspective, randomized, placebo-controlled study - Menopause. 2010 Aug 31 - "Myo-inositol plus diet improved systolic and diastolic blood pressure, HOMA index, cholesterol, and triglyceride serum levels with highly significant differences, compared with the groups treated only with diet and placebo. In the group treated with myo-inositol, a decrease in diastolic blood pressure (-11%), HOMA index (-75%), and serum triglycerides (-20%) and an improvement in high-density lipoprotein cholesterol (22%) were shown ... CONCLUSIONS: Supplementation with myo-inositol may be considered a reliable option in the treatment of metabolic syndrome in postmenopausal women" - Note:  See raysahelian.com/inositol.html  and http://en.wikipedia.org/wiki/Inositol which claim myo-inositol and inositol are the same.  See myo inositol at Amazon.com.

Abstracts:

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