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Anti-aging Research > Energy Supplements
News & Research:
Clinical Study Shows AstaReal(R) Astaxanthin Effective in Reducing both Mental
and Physical Fatigue - yonhapnews.co.kr, 11/7/16 - "AstaReal®
astaxanthin significantly reduced perceived symptoms of mental and physical
fatigue compared to the placebo. These included improvements in clarity of
thinking, concentration, motivation, and mood. Irritation and feeling of body
heaviness were reduced. In the calculation test, an increase in errors observed
in the placebo during the second half of the test was almost eliminated in the
astaxanthin group. Supplementation with astaxanthin also significantly reduced
salivary cortisol, a biomarker for stress" - [Nutra
USA] - See astaxanthin at Amazon.com.
Approach to Examine the Effects of Theacrine (TeaCrine®) Supplementation on
Oxygen Consumption, Hemodynamic Responses, and Subjective Measures of Cognitive
and Psychometric Parameters - J Diet Suppl. 2016 May 10:1-15 -
"Using a two-part approach in humans, the impact of
theacrine (TeaCrine®, TC) was used to examine subjective dose-response, daily
changes in cognitive and psychometric parameters, and changes in gas exchange
and vital signs. ... visual analog scale (VAS) ... Energy, focus, and
concentration increased from baseline values in both doses with no dose-response
effect. VAS responses in the 200 mg for willingness to exercise, anxiety,
motivation to train and libido increased across the measurement period while no
such change was seen with the 400 mg dose. After consuming a single 200 mg dose,
significant group × time interaction effects were seen for energy, fatigue, and
concentration. No changes in resting heart rate, gas exchange, systemic
hemodynamics or side effect profiles were noted" - See
TeaCrine® at Amazon.com.
of chronic trans-resveratrol supplementation on aspects of cognitive function,
mood, sleep, health and cerebral blood flow in healthy, young humans - Br J
Nutr. 2015 Sep 7 - "Subjective ratings of 'fatigue' were
significantly lower across the entire 28 d in the resveratrol condition"
ReserveAge Resveratrol Vegetarian Capsules, 500 Mg, 60-Count
Energizing sick mitochondria with vitamin B3: Effective treatment for
mitochondrial disease - Science Daily, 4/7/14 -
"Vitamins B have recently been turned out to be potent modifiers of energy
metabolism, especially the function of mitochondria. Vitamin B3, (niacin) has
been found to delay the signs of aging in animal models ... Mitochondria power
up all cells in our bodies, by generating fuel, ATP, for all cellular functions
... feeding mice with food supplemented with B3 form, nicotinamide riboside,
delayed their mitochondrial myopathy" - Note: It seems like you could
kill two birds with one stone by taking niacin to raise the good cholesterol.
What Is the Difference Between Niacin & Niacinamide? - LiveStrong.com -
"Your body can convert niacin into niacinamide ...
Niacin and niacinamide have identical function when used as vitamins ...
their pharmacologic properties differ. For example, high doses of niacin can
cause skin flushing. Niacinamide, however, does not have the same
vasodialating, or blood-vessel widening, effects, that niacin has, so it
does not lead to skin flushing" - Note: You'll find
contradictory information on the Internet but niacinamide will not raise HDL
and niacin will. See
niacin at Amazon.com.
One Iron Pill a Day Keeps
Fatigue Away? - Medscape, 8/20/13 - "evidence is
growing that fatigue in non-anaemic, menstruating women with low ferritin can be
influenced positively by iron supplementation ... the authors randomised 198
menstruating women with considerable fatigue (>6 on a 1–10 Likert scale),
ferritin levels less than 50 μg/l and haemoglobin ≥12 g/dl to have 80 mg oral
ferrous sulphate or placebo for 12 weeks ...A total of 47.7% of the patients in
the iron group compared with 28.8% in the placebo group reported decreased
fatigue. Quality of life, depression and anxiety were not affected ... As in all
oral iron trials, darkening of stool leads to possible differentiation of verum
from placebo, therefore, blinding was not totally assured; a substantial
limitation considering the huge placebo effect on fatigue reported in studies
using parenteral iron"
Magnolia officinalis and Phellodendron amurense (Relora(R)) on cortisol and
psychological mood state in moderately stressed subjects - J Int Soc Sports
Nutr. 2013 Aug 7;10(1):37 - "Magnolia (Magnolia
officinalis) and Phellodendron (Phellodendron amurense) barks are medicinal
plants commonly used as traditional remedies for reducing stress and anxiety ...
assessed salivary cortisol exposure and psychological mood state in 56 subjects
(35 men and 21 women) screened for moderate stress and supplemented with a
standardized/patented MP combination (Relora(R), Next Pharmaceuticals) or
Placebo for 4 weeks ... After 4 weeks of supplementation, salivary cortisol
exposure was significantly (p<0.05) lower (-18%) in the Relora group compared to
Placebo. Compared to Placebo, the Relora group had significantly better (p<0.05)
mood state parameters, including lower indices of Overall Stress (-11%), Tension
(-13%), Depression (-20%), Anger (-42%), Fatigue (-31%), and Confusion (-27%),
and higher indices of Global Mood State (+11%) and Vigor (+18%)" - Note:
The biggest affect was on anger (-42%). - See
Relora at Amazon.com.
and minerals can boost energy and enhance mood - Science Daily, 7/16/13 -
"In a series of studies she recently conducted in
Canada, Kaplan found of the 97 adults with diagnosed mood disorders who kept a
three-day food record, a higher intake of vitamins and minerals were
significantly correlated with overall enhanced mental functioning ... Other
vitamins that have been known to enhance mood, said C.J. Geiger, Ph.D.,
president of Geiger & Associates, LLC, and research associate professor in the
division of nutrition at the University of Utah, include 5-Hydroxytryptophan (5
HTP), Vitamins B and D, as well as ginkgo biloba and Omega 3" - See
5-HTP products at Amazon.com
Ginkgo biloba at Amazon.com.
Significant link found between daytime sleepiness and vitamin D - Science
Daily, 12/14/12 - "progressively higher levels of
daytime sleepiness were correlated inversely with progressively lower levels of
vitamin D" - See
vitamin D at Amazon.com.
depression found to be root causes of daytime sleepiness - Science Daily,
6/13/12 - "Three studies being presented June 13 at
sleep 2012 conclude that obesity and depression are the two main culprits making
us excessively sleepy while awake ... Insufficient sleep and obstructive sleep
apnea also play a role; both have been linked to high blood pressure, heart
disease, stroke, depression, diabetes, obesity and accidents"
Iron pills may help women
beat fatigue - BBC News, 6/4/12 -
"Prescribing iron supplements may help some women with fatigue even if they are
not officially anaemic ... A severe shortage of iron is the most common cause of
anaemia resulting in lethargy, weakness and feeling faint ... Nearly 200 women
reporting fatigue, with no medical explanation, took part in the study. Half
were given 80mg oral iron tablets every day, while half were given sugar pills
... iron supplementation for 12 weeks decreased fatigue [scores] by 50%"
- See iron supplements at Amazon.com.
Surprising reasons you're tired all the time - MSNBC, 2/7/12 -
"Anemia ... Diabetes ... Thyroid Disease ... Depression
... Rheumatoid Arthritis"
Top Tips for Fighting Fatigue - ABC News, 1/23/12 - it's a 5 minute video.
Pearls of wisdom from Lucy Liu - USATODAY.com, 1/17/12 -
"Drink water; eat healthy; take vitamins; avoid the sun,
exercise and stay clear of donuts (and other carbohydrates) which make you
Boosting supply of key brain chemical reduces fatigue in mice - Science
Daily, 12/10/10 - "Researchers at Vanderbilt
University have "engineered" a mouse that can run on a treadmill twice as
long as a normal mouse by increasing its supply of acetylcholine ... could
lead to new treatments for neuromuscular disorders such as myasthenia
gravis, which occurs when cholinergic nerve signals fail to reach the
muscles ... The choline transporter is vital to the capacity for muscle
contraction -- including the ability to breathe -- because it regulates the
supply of choline, the precursor to acetylcholine. "We reasoned that giving
more of this protein might enhance muscle function and reduce
nerve-dependent fatigue,"" - See
citicholine at Amazon.com.
Antioxidant Ingredient Proven To Relieve Stress - Science Daily, 9/14/09
- "The 35 people in our study who received capsules
containing superoxide dismutase showed improvement in several signs and
symptoms of perceived stress and fatigue" - See
SOD supplements at Amazon.com.
Fatigue Predicts Mortality in Older Adults - J Am Geriatr Soc. 2008 Sep
22 - "Mortality rates at 10 years were 59% (123/210)
for older adults with fatigue, versus 38% (106/282) for those without
Rhodiola for What Ails You? - Dr. Weil, 5/15/08 -
"A 2002 review in Herbalgram, the Journal of the
American Botanical Council, reported that over the years, numerous studies
of rhodiola in humans and animals have shown that it helps prevent fatigue,
stress and the damaging effects of oxygen deprivation. Evidence also
suggests that it has an antioxidant effect, enhances immune system function
and can increase sexual energy ... A study published in 2007 in the Nordic
Journal of Psychiatry showed that patients with mild-to-moderate depression
who took a rhodiola extract reported fewer symptoms than those who took a
placebo. And a study by researchers at the University of California at
Irvine found that fruit flies that ate a diet supplemented with rhodiola
lived an average of 10 percent longer than flies that didn't eat this herb"
Rhodiola rosea at Amazon.com.
Low-intensity Exercise Reduces Fatigue Symptoms By 65 Percent, Study Finds
- Science Daily, 2/28/08 - "Sedentary people who
regularly complain of fatigue can increase their energy levels by 20 percent
and decrease their fatigue by 65 percent by engaging in regular, low
Supplements: Myths and Facts - ABC News, 2/22/06
Rev Up Your
Energy - WebMD, 8/30/05
Energy for Sale - WebMD, 8/30/05
Foods to Fight
Fatigue - WebMD
Drowsy Days May Signal Depression - WebMD, 8/12/05 -
"After crunching the numbers, depression was the No.
1 risk factor for excessive daytime sleepiness. BMI came second. Typical
sleep duration was third, followed by diabetes, smoking, and, finally, sleep
- NADH, the supervitamin
body and mind energizer - by James South MA - See
nicotinamide adenine dinucleotide at Amazon.com.
- Energizing the
Elderly? - Dr. Weil, 3/24/05
- Drowsy During the Day?
- Dr. Weil, 7/8/04
Lack Energy? Maybe It's Your Magnesium Level - Science Daily, 5/10/04 -
"inadequate magnesium is associated with a need for
increased oxygen during exercise. They found that during moderate activity,
those with low magnesium levels in muscle are likely to use more energy—and
therefore to tire more quickly—than those with adequate levels" -
- Energy to Burn
- Men's Health/WebMD, 9/1/03
Iron Fights Fatigue in Women - Natural Foods Merchandiser, 9/03
Iron Supplements May Help Fatigued Women - Doctor's Guide, 5/22/03 - "Women
who experience unexplained fatigue, but who are not
may benefit from iron supplementation ...The level
of fatigue after one month decreased by - 1.82/6.37 points (29%) in the iron
group, compared with - 0.85/6.46 points (13%) in the placebo group ... the
lower limit for serum ferritin concentration is controversial: iron stores
in the bone marrow may serve as a better indicator of iron deficiency, they
add. The lower reference limits for serum ferritin and haemoglobin
concentrations have been considered too low for women and it has been
suggested should be the same as for men"
Ribose Recovery - Nutrition Science News, 3/01
Bioenergetic Therapy for Aging - Life Extension Magazine, 2/01
Enada Reduces Chronic Fatigue Symptoms - Nutrition Science News, 8/99
- Consult Your
Pharmacist - The Many Faces of Fatigue - Medscape, 12/98
Coenzyme Q10: It
May Just Be the Miracle Vitamin of the 1990s - The Nutrition Reporter
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