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Home > Anti-aging Research > Coenzyme Q10.

Coenzyme Q10 (ubiquinone)

Specific Recommendations:

News & Research:

  • Insulin Resistance - Dr. Weil - "Supplements: ... Coenzyme Q10 ... Alpha-lipoic acid ... Magnesium ... Chromium"
  • Low Coenzyme Q10 Linked to Multiple System Atrophy - Medscape, 7/13/16 - "We know now that the presence of CoQ10 levels are decreased in patients even without COQ2 variants. That means supplementation of CoQ10 may be effective for patients with or without COQ2 mutations, so it may be effective for all MSA patients ... MSA is a progressive neurodegenerative disease, with patients often experiencing rapid functional decline and poor response to medical therapy ... The study, he said, "presents new data," and the findings are "significant" as CoQ10 plays an important role in mitochondrial function and energy production in cells, in particular neurons in the brain" - See ubiquinol products at Amazon.com.
  • Coenzyme Q10 helps veterans battle gulf war illness symptoms - Science Daily, 11/3/14 - "Roughly one-third of the 700,000 United States troops who fought in the 1990-1991 Persian Gulf War have subsequently developed a distinct set of chronic health problems, dubbed Gulf War illness ... a high quality brand of coenzyme Q10 (CoQ10) -- a compound commonly sold as a dietary supplement -- provides health benefits to persons suffering from Gulf War illness symptoms ... Evidence instead links Gulf War illness to chemical exposures ... These chemicals can damage mitochondria, which generate the energy our cells need to do their jobs ... 80 percent of those who received 100mg of CoQ10 had improvement in physical function. The degree of improvement correlated to the degree in which CoQ10 levels in the blood increased ... Gulf War illness symptoms like headaches, fatigue with exertion, irritability, recall problems and muscle pain also improved"
  • Novel antioxidant makes old arteries seem young again, study shows - Science Daily, 5/6/14 - "When the research team gave old mice -- the equivalent of 70- to 80-year-old humans -- water containing an antioxidant known as MitoQ for four weeks, their arteries functioned as well as the arteries of mice with an equivalent human age of just 25 to 35 years ... MitoQ completely restored endothelial function in the old mice. They looked like young mice ... Biochemists manufactured MitoQ by adding a molecule to ubiquinone (also known as coenzyme Q10), a naturally occurring antioxidant. The additional molecule makes the ubiquinone become concentrated in mitochondria ... the MitoQ treatment increased levels of nitric oxide, reduced oxidative stress and improved the health of the mitochondria in the arteries of old mice" - See MitoQ at Amazon.com.
  • Antioxidant drug knocks down multiple sclerosis-like disease in mice - Science Daily, 12/26/13 - "The antioxidant -- called MitoQ -- has shown some promise in fighting neurodegenerative diseases. But this is the first time it has been shown to significantly reverse an MS-like disease in an animal ... the researchers induced mice to contract a disease called experimental autoimmune encephalomyelitis, or EAE, which is very similar to MS in humans ... After 14 days, the EAE mice that had been treated with the MitoQ exhibited reduced inflammatory markers and increased neuronal activity in the spinal cord -- an affected brain region in MS -- that showed their EAE symptoms were being improved by the treatment. The mice also showed reduced loss of axons, or nerve fibers and reduced neurological disabilities associated with the EAE. The mice that had been pre-treated with the MitoQ showed the least problems. The mice that had been treated with MitoQ after EAE also showed many fewer problems than mice who were just induced to get the EAE and then given no treatment"
  • First drug to significantly improve heart failure mortality in over a decade - Science Daily, 5/25/13 - "Coenzyme Q10 decreases all cause mortality by half ... is the first drug to improve heart failure mortality in over a decade and should be added to standard treatment ... Double blind controlled trials have shown that CoQ10 improves symptoms, functional capacity and quality of life in patients with heart failure with no side effects ... Other heart failure medications block rather than enhance cellular processes and may have side effects. Supplementation with CoQ10, which is a natural and safe substance, corrects a deficiency in the body and blocks the vicious metabolic cycle in chronic heart failure called the energy starved heart"
  • CoQ10 and L-carnitine for Statin Myalgia? - Medscape, 1/4/13 - "In summary, it has been proposed that CoQ10 can help to treat statin myalgia. While this is not conclusive, there are two randomized controlled trials showing significant improvements in the severity of muscle pain with the use of CoQ10 in patients treated with statins. Thus, it is not unreasonable to supplement a patient who is experiencing muscle pains on a statin with CoQ10. While there are no clinical trials showing improvements in muscle pain with the use of l-carnitine, patients who experience statin myalgia frequently have carnitine abnormalities. It is too soon to recommend l-carnitine for statin myalgia, but future trials should test this supplement to see if it has any place for this adverse effect. Other common alternatives for treating statin myalgias are supplementation with vitamin D or vitamin B12, especially in the setting of suboptimal serum levels" - See ubiquinol products at Amazon.com, Jarrow Formulas, GPLC, Glyco Carn, 500 mg, 60 Veggie Caps at iHerb and acetyl l-carnitine products at Amazon.com.
  • Cholesterol medicine affects energy production in muscles - Science Daily, 1/3/13 - "A well-known side effect of statin therapy is muscle pain. Up to 75 per cent of the physically active patients undergoing treatment for high cholesterol experience pain. This may keep people away from either taking their medicine or from taking exercise -- both of which are bad choices ... Scientists also showed that the patients examined who were being treated with statins had low levels of the key protein Q10. Q10 depletion and ensuing lower energy production in the muscles could be the biological cause of the muscle pain that is a problem for many patients"
  • Antioxidant has potential in the Alzheimer's fight - Science Daily, 12/14/11 - "When you cut an apple and leave it out, it turns brown. Squeeze the apple with lemon juice, an antioxidant, and the process slows down ... Simply put, that same "browning" process-known as oxidative stress-happens in the brain as Alzheimer's disease sets in ... an antioxidant can delay the onset of all the indicators of Alzheimer's disease, including cognitive decline. The researchers administered an antioxidant compound called MitoQ to mice genetically engineered to develop Alzheimer's. The results of their study were published in the Nov. 2 issue of the Journal of Neuroscience ... Oxidative stress is believed to cause neurons in the brain to die, resulting in Alzheimer's ... The brain consumes 20 percent of the oxygen in the body even though it only makes up 5 percent of the volume, so it's particularly susceptible to oxidative stress ... MitoQ selectively accumulates in the mitochondria" - Note:  I couldn't find the ingredients but it sounds like a form of co-enzyme Q10.  Here's the form I take: ubiquinol products at Amazon.com
  • CoQ10 may boost antioxidant defenses in people with atherosclerosis - Nutra USA, 10/28/11 - "A daily CoQ10 dose of 150 mg was associated with 29% lower levels of malondialdehyde (MDA - a reactive carbonyl compound and a well-established marker of oxidative stress) after eight weeks, compared with the placebo group ... In addition, after 12 weeks of supplementation, the CoQ10 supplement appeared to stimulate the body’s antioxidant defenses and levels of the antioxidant enzymes catalase and superoxide dismutase (SOD) were 230% and 78% higher than the placebo group, respectively ... blood levels increased of CoQ10 increased in the high dose group by 189% after 12 weeks, but no significant increases were observed in the 60 mg group" - [Abstract]
  • CoQ10 may reduce muscle damage during intensive exercise - Nutra USA, 10/27/11 - "Twenty ultra-runners participated in the study and were divided into two equal groups. One group received one 30 mg capsule of CoQ10 two days before the test, three 30 mg capsules the day before the test, and one capsule one hour before the test. The other group received placebo at the same time. The test involved a 50 km distance run across Europe’s highest road in the Sierra Nevada ... Results showed that the placebo group displayed a 100% increase in levels of 8-OHdG, which <i>“a sensitive indicator of DNA damage as a result of oxidative stress”,</i> said the researchers, compared with an increase of 37.5% in the runners taking the CoQ10 supplements ... The data also indicated that CoQ10 countered the over-expression of certain pro-inflammatory compounds after exercise ... a reduction in levels of creatinine in the urine was observed in the CoQ10 group, compared with the placebo group. Creatinine is produced from creatine and high levels are a marker of muscle break down (or kidney damage) ... CoQ10 supplementation reduces creatinine excretion and therefore decrease muscle damage during physical performance" - [Abstract]
  • Natural therapies: Cardiologists examine alternatives to halt high blood pressure - Science Daily, 8/30/11 - "The shining star among supplements is coenzyme Q10, an enzyme involved in energy production that also acts as an antioxidant. Patients with hypertension tend to have lower levels of the enzyme, and a meta-analysis -- an overarching analysis of past studies -- found that treatment with coenzyme Q10 supplements significantly reduced blood pressure ... Coenzyme Q10 has a pretty profound effect on blood pressure, but whenever research is based on a collection of other data you have to have some skepticism ... potassium helps lower blood pressure, and there is evidence that increasing the amount of potassium we get through the foods we eat could carry some of the same mild benefits as taking supplements" - See ubiquinol products at Amazon.com and potassium citrate at Amazon.com.
  • Pine bark extract plus CoQ10 shows benefits for heart failure patients - Nutra USA, 6/23/11 - "12 weeks of daily supplementation with 350 milligrams of CoQ10 (Kaneka) and 105 milligrams of the branded pine bark extract Pycnogenol ... recruited 53 heart failure patients aged between 54 and 68 were randomly assigned to receive either the PycnoQ10 supplement or placebo for 12 weeks ... systolic and diastolic blood pressure decreased following the CoQ10-pine bark combination, from 139.2 to 133.2 mmHg and 82.3 to 77.3 mmHg, respectively. Systolic and diastolic blood pressure decreased from 140.3 to 139.5 mmHg and 83.4 to 81.2 mmHg, respectively, in the placebo group ... In addition to increases in the amount of blood pumped by the heart, the researchers also reported improvements in heart rate were also observed in the PycnoQ10 supplement group from 78.4 to 74.2 beats per minute, compared with a decrease from 79.1 to 78.4 in the placebo group" - [Abstract] - See Pycnogenol at Amazon.com and ubiquinol products at Amazon.com.
  • CoQ10 may protect against obesity problems: Study - Nutra USA, 10/15/09 - "We propose, in view of our study, that CoQ10, when given orally, is able to target the liver tissue, and to lessen inflammatory stress associated with obesity in mice in this tissue, independent on any action on lipid peroxidation" - [Abstract]
  • CoQ10 may boost sperm quality: Study - Nutra USA, 6/16/09 - "randomly assigned them to receive a daily CoQ10 supplement (300 mg, Kaneka, Japan) or placebo for 26 weeks. This was followed by 30 weeks with no intervention ... The Tehran-based researchers reported a significant improvement in both sperm density and motility following supplements of the coenzyme. A positive association was also found with regards to sperm count. Further analysis showed an increase in the percent of normal forms of sperm" - [Abstract]
  • CoQ10 Improves Endothelial Dysfunction in Statin-Treated Type 2 Diabetics - Medscape, 5/29/09 - "Study subjects were randomized to receive either 200 mg/day of oral CoQ10 or placebo for 12 weeks ... Our absolute improvement in FMD of 1% with CoQ10 supplementation may potentially translate to a 10-25% reduction in residual cardiovascular risk in these patients"
  • Taking Statins? Five Ways to Boost Your Energy - ABC News, 4/14/09 - "It's a cruel irony that if statins make patients more lethargic, it could impair their ability to exercise or make dietary changes that would help them address their high cholesterol ... some studies have found that patients' energy levels increased while using CoQ10 and statins together ... Try pomegranate juice or a small chunk of dark chocolate, both of which have beneficial antioxidants ... Skimping on sleep has been found to increase calcium deposit build-up in your arteries"
  • Statin study: Lower cholesterol, diminished joy of sex linked - USA Today, 3/5/09 - "In the study, sexual pleasure sank along with LDL levels ... Some studies have found that statins improve sexual function, probably because the pills can improve blood flow to the genital area, Golomb says. But she says the drugs also may reduce Coenzyme Q10, a nutrient that helps cells convert oxygen, blood and glucose into energy. "Orgasm is a high-energy activity," so losing the nutrient could weaken sexual pleasure, she says" - See ubiquinol products at Amazon.com.
  • Statins' Adverse Effects Documented - Science Daily, 1/29/09 - "Coenzyme Q10 ("Q10") is a compound central to the process of making energy within mitochondria and quenching free radicals. However, statins lower Q10 levels because they work by blocking the pathway involved in cholesterol production – the same pathway by which Q10 is produced. Statins also reduce the blood cholesterol that transports Q10 and other fat-soluble antioxidants ... "The loss of Q10 leads to loss of cell energy and increased free radicals which, in turn, can further damage mitochondrial DNA," said Golomb, who explained that loss of Q10 may lead to a greater likelihood of symptoms arising from statins in patients with existing mitochondrial damage – since these people especially rely on ample Q10 to help bypass this damage" - My favorite is QH-Absorb by Jarrow.
  • Reduced CoQ10 shows superior bioavailability: SGTI study - Nutra USA, 1/21/09
  • Product Review: CoQ10 and Ubiquinol Supplements - consumerlab.com, 1/13/09
  • Wrinkle creams: Your guide to younger looking skin - CNN - "Coenzyme Q10 is a nutrient that helps regulate energy production in cells. Some studies have shown reduction in fine wrinkles around the eyes with no side effects"
  • CoQ10 bioavailability boost from soft gels: Study - Nutra USA, 1/12/09 - "Researchers from Canada’s KGK Synergize compared CoQ10 formulations from hard and soft gel capsules, and found the reduced form from the latter resulted in a 3.3-fold higher blood level of CoQ10 than the former ... formulated by Soft Gel Technologies" - See iHerb search of "Soft Gel Technologies".  I'm sticking with QH-Absorb by Jarrow because I don't trust the NOW brand.  I feel that it probably just hasn't been studied yet.
  • Coenzyme Q-10 Depletion Linked to Worse Heart Failure Outcomes - Medscape, 10/22/08 - "Low plasma concentration of coenzyme Q-10 is an independent predictor of reduced survival in patients with chronic heart failure"
  • New Health Drink? Chemist Goes Nano With CoQ10 - Science Daily, 7/24/08
  • CoQ10 may cut muscle injuries for athletes - Nutra USA, 5/5/08 - "The volunteers had daily training sessions of five and a half hours per day for six days during the intervention period. At day three and five of the six day training period, the researchers report that both groups experienced increased in serum creatine kinase activity and the concentration of myoglobin, but these increases were significantly lower in the group receiving the CoQ10 supplements ... Elevated levels of the enzyme are indicative of muscle damage and injury ... levels of lipid peroxide, a marker of oxidative stress, were also lower in the CoQ10 group after three and five days of training" - [Abstract]
  • Migraine Patients May Benefit From Magnesium or CoQ10 - Clinical Psychiatry News, 8/07 - "The most important supplement, according to Dr. Mauskop, is magnesium. “It's known that up to 50% of people with acute migraine have a magnesium deficiency. … It is much more effective to treat them with a product they're deficient in rather than using drugs,” ... Research has found that, for migraine, CoQ10 at 300 mg/day is effective, and that for Parkinson's disease 1,200 mg/day is effective"
  • Report: Has Your Coq10 Become Obsolete? - Life Extension Magazine, 1/07 - "scientists have demonstrated that the ubiquinol form of CoQ10 provides anti-aging effects that are far superior to those associated with the conventional ubiquinone form used by millions of Americans each day" - See ubiquinol products at Amazon.com.
  • Novel Form Of Coq10 - Life Extension Magazine, 12/06
  • Coenzyme Q10 review - ConsumerLab.com, 10/16/06
  • More support for CoQ10’s benefits for heart health - Nutra USA, 9/12/06 - "the heart's functional capacity improved significantly by nine per cent, as measured by the peak volume of oxygen consumed (VO2), for the CoQ10 compared to placebo"
  • Report: Coq10'S New Benefits - Life Extension Magazine, 8/06
  • CoQ10 may protect against Alzheimer’s - Nutra USA, 4/24/06
  • Coenzyme Q10 for Migraine Prophylaxis - Clinical Psychiatry News, 3/06 - "150 mg of coenzyme Q10 each day ... The study's primary outcome measure was the percentage of patients who achieved a greater than 50% reduction in the number of days with migraine. A total of 61.3% of patients met that outcome measure by 3 months, and 93.5% had at least a 25% reduction"
  • CoQ10’s “Other” Health Benefits - Life Extension Magazine, 2/06 - "The latest findings suggest that, along with its heart-protective effects, CoQ10 may slow or improve some degenerative diseases, support cancer remission, counteract the toxic effects of chemotherapy, and decrease the incidence of migraine headaches. Additionally, recent findings indicate that coenzyme Q10 may have applications in promoting fertility, protecting auditory function, supporting longevity, boosting learning capability, sustaining muscle health and much more"
  • Coenzyme Q10 New Applications for Cancer Therapy - Life Extension Magazine, 10/05
  • Four powerhouse nutrients - Functional Foods and Nutraceuticals, 4/05 - "L-carnitine shuttles fuel into cells to be burned as energy; coenzyme Q10 sparks the energy within the cells; ribose is a component of adenosine triphosphate (ATP); and alpha-lipoic acid increases ATP levels"
  • Coenzyme Q10 Lessens Muscle-Related Side Effects in Patients on Statins - Doctor's Guide, 3/7/05 - "Patients with significant myopathy who are taking statin therapy have a significant decrease in myopathic pain after 30 days of supplementation with coenzyme Q10" - See ubiquinol at Amazon.com.
  • The high five for hypertension - Functional Foods & Nutraceuticals, 12/04 - "Co-enzyme Q10 ... Omega-3 fatty acids ... Garlic ... L-arginine ... Calcium"
  • Innovative Research and Applications for CoQ10 - Life Extension Magazine, 8/04 - "biomedical researchers are discovering that CoQ10 shows promising effects against disorders as far-ranging as kidney failure, heart disease, muscular dystrophy, and macular degeneration"
  • Proprietary CoQ10 formulation demonstrates superior absorption - Nutra USA, 6/30/04
  • Atorvastatin Reduces Blood CoQ10 Levels - Medscape, 6/22/04 - "Even brief exposure to atorvastatin causes a marked decrease in blood CoQ10 concentration ... Widespread inhibition of CoQ10 synthesis could explain the most commonly reported adverse effects of statins, especially exercise intolerance, myalgia, and myoglobinuria"
  • Coenzyme Q10 May Ward Off Migraine Attacks - Medscape, 4/29/04 - "migraine may be caused by a decrease in mitochondrial energy reserve ... 100 mg of CoQ10 three times a day ... Approximately 48% of those who took CoQ10 had a 50% response rate during the three-month study, while this occurred in about 14% of those taking a placebo"
  • Coenzyme Q10 & Fertility - Physician's Weekly, 4/5/04
  • Cardiologists Overlook Lifesaving Discovery - Life Extension Magazine, 2/04
  • Coenzyme Q10 May Play Positive Role in Treatment of Male Infertility - Medscape, 1/30/04 - "Patients underwent oral administration of CoQ10, 200 mg/day twice daily for six months ... After treatment, CoQ10 levels increased in seminal plasma; the mean value rising significantly from 42.0 +/- 5.1 ng/mL at baseline to 127.1 +/- 1.9 ng/mL after six months of CoQ10 administration"
  • Coenzyme Q10 review - ConsumerLab.com, 1/13/03 - "There was no detectable CoQ10 in one product, another had only 71% of its claimed amount, and a third exceeded its claimed amount by 75%"
  • Coenzyme Q10 Helps Sperm Movement - WebMD, 1/12/04 - "Researchers say coenzyme Q10 is known to be active in the testes and is an antioxidant that plays an important role in forming the membranes and other structures within cells by fighting the effects of oxidative stress ... researchers looked at the effects of daily oral supplementation with 200 mg of coenzyme Q10"
  • Reason for concern? - Wellness Insider, 11/25/03 - "Dr. Golomb feels the potential side effects of statins, which include liver dysfunction, muscle pain (rhabdomyolysis), and potentially, muscle breakdown, have been significantly downplayed. She also feels that statins, especially at higher doses, contribute to memory loss and to the depletion of coenzyme Q10, a naturally occurring antioxidant-like nutrient vital to the production of energy"
  • Water Soluble Form of Coenzyme Q10 Suggested for Migraine Prophylaxis - Doctor's Guide, 9/30/03 - "researchers used a new water-soluble form of coenzyme Q10 at 100 mg three times daily for migraine prophylaxis ... Of the Q10 group, 47.6% of the patients had a 50% response for attack frequency, compared to 14.3% for the placebo group, resulting in a therapeutic gain of about 33.3%"
  • Coenzyme Q10 Beneficial for People with Kidney Failure - New Hope Natural Media, 7/17/03
  • Guarding Your Gums? - Dr. Weil, 6/16/03 - "Periodontal disease is a chronic gum infection caused by bacteria in plaque ... Coenzyme Q10: Take 120 mg per day of a soft-gel form with meals ... young women who get less than 800 mg of calcium a day have double the risk of periodontal disease" - See iHerb.  At least two randomized trials of the effects of coenzyme Q10 (another antioxidant) on blood pressure have been reported. In the first,[20] 59 treated hypertensives were randomized to either coenzyme Q10 (60 mg twice daily) or vitamin B (placebo); after 8 weeks, clinic blood pressure was 14/7 mm Hg lower in the treated group. In the second,[21] 83 patients with isolated systolic hypertension were treated with coenzyme Q10 (using the same dose as the earlier study) for 12 weeks. The mean reduction of blood pressure was 17.8/7.3 mm Hg"
  • Coenzyme Q10 Deficiency Associated with Genetic Coordination Disorder - New Hope Natural Media, 6/12/03
  • How To Prevent Breast Cancer Anti-Cancer Power of Coenzyme Q10 - Life Extension Magazine, 1/96
  • Coenzyme Q10 Improves High Blood Pressure - New Hope Natural Media, 1/9/03 - "recruited 83 people with a condition called isolated systolic hypertension (ISH), in which the higher blood pressure ... These people were assigned to take either 60 mg of CoQ10 twice daily or a placebo for 12 weeks ... The people taking CoQ10 had an 18-point (18 mm Hg) reduction in systolic blood pressure (from 165 to 147 mm Hg), compared with only a 2-point decline in the placebo group ... ISH is the most common type of high blood pressure in the United States"
  • The First Therapy Shown To Slow Progression of Parkinson's Disease - Life Extension Magazine, 1/03
  • Coenzyme Q10 Appears To Slow Parkinson's Disease Progression - Doctor's Guide, 11/6/02
  • Study Suggests Coenzyme Q10 Slows Functional Decline In Parkinson's Disease - Doctor's Guide, 10/15/02
  • Coenzyme Q10 May Slow Parkinson's - WebMD, 10/14/02 - "High doses of the popular supplement coenzyme Q10 helps slow the progression of Parkinson's disease in some patients by as much as half ... Their study, published in the Oct. 15 issue of Archives of Neurology, is the latest to examine the possible benefits of coenzyme Q10, a vitamin-like compound naturally produced in the body and used by cells to make energy and protect against cellular damage"
  • MEDLINE Abstracts: Antioxidants and the Aging Brain - Medscape, 9/27/02 - "Combinations of antioxidants might be of even greater potential benefit for AD, especially if the agents worked in different cellular compartments or had complementary activity (e.g. vitamins E, C and ubiquinone). Naturally-occurring compounds with antioxidant capacity are available and widely marketed (e.g. vitamin C, ubiquinone, lipoic acid, beta-carotene, creatine, melatonin, curcumin) and synthetic compounds are under development by industry" - Again, a broad spectrum of anti-oxidants, not just one or two.
  • CoQ10, the Wonder Nutrienticon - Vitacost, 9/6/02 - "It was found that the concentrations of CoQ10 were significantly decreased in both plasma and whole blood of asthmatic sufferers compared with that of the healthy volunteers. The researchers speculated that sub-optimal concentrations of CoQ10 may play a possible contribution in patients with asthma"
  • Dr. Julian M. Whitaker Petitions FDA to Include CoQ10 Use Recommendation in All Statin Drug Labeling - Life Extension Magazine, 8/02 - "On May 23, 2002, Dr. Julian M. Whitaker filed two citizens petitions with the Food and Drug Administration. The petitions call on the Commissioner of Food and Drugs to change the labeling of all HMG CoA reductase inhibitor drugs (the so-called statin drugs), and to issue a Medication Guide, warning consumers of the need to take coenzyme Q10 (CoQ10) whenever they take a statin drug"
  • Coenzyme Q10 Effective for Migraine Prevention - New Hope Natural Media, 7/18/02 - "In the new study, 31 migraine sufferers were given 150 mg of CoQ10 per day for three months. The average number of days per month on which participants experienced headaches was 60% lower during the last two months of CoQ10 treatment than during the month prior to treatment. In addition, the average number of migraine attacks per month decreased by 42% with CoQ10 ... Two other nutrients that play a role in intracellular energy production (magnesium and riboflavin) have also been shown to reduce the recurrence rate of migraines"
  • How CoQ10 Protects Brain Cells - Life Extension Magazine, 10/01 - "Newly published research suggests that CoQ10 can protect brain cells from neurotoxicity and excitotoxicity, while even powerful antioxidants cannot. CoQ10 proved highly effective, while simple antioxidants were ineffective, in protecting PC-12 cells (neuron-like rat adrenal cells commonly used in neurobiological research) from the excitotoxic effects of glutamate and from the Parkinson’s disease-like effects of the neurotoxin MPP+. L-deprenyl (the drug selegilene) also proved effective, though not as effective as CoQ10"
  • ACSM Conference Unveils Performance Enhancers - Nutrition Science News, 9/01 - "Researchers have found that coenzyme Q10 (Co-Q10 or ubiquinone) can lower blood pressure in hypertensive people"
  • Trial of Coenzyme Q10 in Isolated Systolic Hypertension - Medscape, South Med J 94(11):1112-1117, 2001 - "The mechanisms underlying essential hypertension remain uncertain. A causal role for insulin resistance has been suggested,[35] and high levels of plasma insulin have frequently been found in patients with high blood pressure"
  • How CoQ10 Protects Your Cardiovascular System - Life Extension Magazine, 4/00
  • Drugs That Deplete- Nutrients That Heal - Life Extension Magazine, 7/00 - "A large number of drugs deplete Coenzyme Q10. These include such widely used tricyclic antidepressants as Elavil (amitriptyline) and Tofranil (imipramine), the anti-psychotic drug Haloperidol, cholesterol-lowering statin drugs such as Lovastatin and Pravastatin, beta-blockers, anti-diabetic sulfonylurea drugs such as Glucotrol (glipizide) and Micronase (glyburide), and the anti-hypertension drug Clonidine."

Abstracts:

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