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Anafranil® (clomipramine)

Related Topics:

• Anafranil (clomipramine) / Auroix (moclobemide) / Buspar (buspirone) / Celexa (citalopram) / Cymbalta (duloxetine) / ECT / Edronax (reboxetine) / Effexor (venlafaxine) / gepirone / Lexapro (escitalopram) / Luvox (fluvoxamine) / Paxil (paroxetine) / Pristiq (desvenlafaxine) / Prozac (fluoxetine) / Remeron (mirtazapine) / RU-486 (mifepristone) / Serzone (nefazodone) / tianeptine / tricyclics / Wellbutrin (bupropion) / Zoloft (sertraline)

• St. John's wort / 5-HTP / SAMe / NADH / Omega-3 / tyrosine / acetyl-l-carnitine / DHEA / phenylalanine / ginkgo / phosphatidylserine / folate / antidepressants

News & Research:

• Bad Taste Of Drugs May Affect Treatment Compliance, Study Findings Suggest - Doctor's Guide, 3/29/00 - "four tricyclic anti-depressants Schiffman and Zervakis studied (clomipramine HCI, desipramine HCI, doxepin HCI and imipramine HCI) produced similar taste complaints among all subjects"
• Clomipramine More Effective Than Desipramine For Body Dysmorphic Disorder - Doctor's Guide, 10/26/99 - "Clomipramine at 25-75 mg was found to be significantly more effective than placebo in reducing irritability as well as other symptoms associated with PMDD"
• New Guidelines To Set Standards For Best Treatment Of OCD - Doctor's Guide, 5/12/97 - "Experts rated the side effects of the four SSRIs (fluoxetine, fluvoxamine, paroxetine and sertraline) as generally better tolerated than the one SRI, clomipramine"

Abstracts:

• Which antidepressants have demonstrated superior efficacy? A review of the evidence - Int Clin Psychopharmacol. 2007 Nov;22(6):323-329 - "Criteria were defined to judge the strength of evidence. Two pivotal studies in moderate-to-severe major depressive disorder that demonstrate superiority on the primary efficacy measure, or alternatively one pivotal study supported by consistent results from meta-analyses, was considered to constitute evidence for definite superiority. Three antidepressants met these criteria: clomipramine, venlafaxine, and escitalopram. Three antidepressants were found to have probable superiority: milnacipran, duloxetine, and mirtazapine. Only escitalopram was found to have definite superiority in the treatment of severe depression; probable superiority was identified for venlafaxine and possible superiority for milnacipran and clomipra"

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