Home > Anti-aging Research > Triglycerides

Triglycerides

Relate Topics  Popular Supplements  Alternative News  General Information  Other News  Supplement Stores  Related Searches

Note:  See my recommendation, Mega Twin EPA at Amazon.com or Jarrow Max DHA at Amazon.com.  Also my page on Essential Fatty Acids.

Related Topics:

• cholesterol concerns / HDL cholesterol / statins / homocysteine / inflammation / heart disease / strokes / red yeast rice / policosanol / guggul / pantethine / artichoke / inositol hexanicotinate / triglycerides / green tea / hesperidin / hypertension / trans fatty acids

Popular Supplements:

• omega-3 fish oil / pantethine / guggul / niacin / green tea / chromium / garlic / fructo-oligosaccharides (FOS) / inositol hexanicotinate / Sytrinol

Alternative News:

• Lipid metabolism disorders and lipid mediator changes of mice in response to long-term exposure to high-fat and high sucrose diets and ameliorative effects of mulberry leaves - Food Funct 2022 Mar 31 - "Mulberry leaves exhibit anti-lipogenic and lipid-lowering effects. However, the lipid biomarkers and underlying mechanisms for the improvement of the action of mulberry leaves on obesity and lipid metabolism disorders have not been sufficiently investigated yet ... mulberry leaf water extract (MLWE) ... Our results showed that MLWE supplementation not only decreased body weight gain, serum total triglycerides, low-density lipoprotein cholesterol, alanine transaminase and aspartate transaminase levels, but also increased the serum level of high-density lipoprotein cholesterol. In addition, MLWE supplementation also ameliorated hepatic steatosis and lipid accumulation" - See mulberry leaf extract at Amazon.com.
• Metformin maintains intrahepatic triglyceride content through increased hepatic de novo lipogenesis - Eur J Endocrinol 2022 Jan 1 - "intrahepatic triglyceride (IHTG) ... hepatic de novo lipogenesis (DNL) and fatty acid (FA) oxidation ... Twelve weeks treatment with metformin resulted in a significant reduction in body weight and improved insulin sensitivity, but IHTG content and FA oxidation remained unchanged. Metformin treatment was associated with a significant decrease in VLDL-triglyceride (TG) concentrations and a significant increase in the relative contribution of DNL-derived FAs to VLDL-TG. There were subtle and relatively few changes in subcutaneous adipose tissue FA metabolism and the plasma metabolome with metformin treatment" - See metformin at ReliableRX.
• Effects of artichoke leaf extract supplementation or artichoke juice consumption on lipid profile: A systematic review and dose-response meta-analysis of randomized controlled trials - Phytother Res 2021 Sep 27 - "artichoke significantly reduced TG (weighed mean difference [WMD]: -17.01 mg/dl, 95% CI: -23.88, -10.13, p = .011), TC (WMD: -17.01 mg/dl, 95% CI: -23.88, -10.13, p < .001), and LDL-C (WMD: -17.48 mg/dl, 95%CI: -25.44, -9.53, p < .001). No significant effect of artichoke on HDL-C level was detected (WMD: 0.78 mg/dl, 95%CI: -0.93, 2.49, p = .371). Combining the two effect sizes revealed that artichoke juice supplementation significantly reduced TG (WMD: -3.34 mg/dl, 95%CI: -5.51, -1.17, p = .003), TC (WMD: -18.04 mg/dl, 95%CI: -20.30, -15.78, p < .001), LDL-C (WMD: -1.75 mg/dl, 95%CI: -3.02, -0.48, p = .007), and HDL-C levels (WMD: -4.21 mg/dl, 95%CI: -5.49, -2.93, p < .001). In conclusion, we found that artichoke supplementation may favor CVD prevention by acting in improving the lipid profile" - See artichoke extract at Amazon.com.
• Effects of guar gum supplementation on the lipid profile: A systematic review and meta-analysis of randomized controlled trials - Nutr Metab Cardiovasc Dis 2021 Aug 21 - "Guar gum supplementation significantly reduced serum LDL-C and TC levels in patients with cardiometabolic problems, but had neutral effects on TG and HDL-C levels" - See guar gum capsules at Amazon.com.  It's also used in ice cream recipes to make it have a creamier texture.
• Triglyceride-induced cardiac lipotoxicity is mitigated by Silybum marianum - Atherosclerosis 2021 Mar 27 - "Silybum marianum (SM) is an herbal product with cytoprotective and antioxidant properties. We have previously demonstrated that SM ameliorates ventricular remodeling and improves cardiac performance. Here, we evaluated whether SM could exert beneficial effects against cardiac lipotoxicity in a pig model of closed-chest myocardial infarction (MI) ... SM administration reduces plasma triglyceride levels through attenuation of triglyceride intestinal absorption and modulates cardiac lipotoxicity in the ischemic myocardium, likely contributing to improve ventricular remodeling" - See silymarin at Amazon.com.
• Omega-3 Polyunsaturated Fatty Acid Supplementation in Patients with Lower Extremity Arterial Disease - J Am Coll Nutr 2021 Mar 22 - "This meta-analysis showed that the use of marine-based omega-3 PUFAs was significantly associated with a reduced level of triglycerides. The strength of the association depended on the dosage of eicosapentaenoic acid" - See omega-3 supplements at Amazon.com.
• Effectiveness of the piperine-supplemented Curcuma longa L. in metabolic control of patients with type 2 diabetes: a randomised double-blind placebo-controlled clinical trial - Int J Food Sci Nutr 2021 Feb 14 - "A randomised double-blind placebo-controlled clinical trial was conducted with 71 participants divided into a Curcuma longa L. group (500 mg/day with piperine 5 mg) and a placebo group, for 120 days ... The curcuma group presented a significantly decreased glycaemia (p=.013), glycated haemoglobin (p=.015), HOMA index (p=.037) and triglycerides (TGs) (p=.002). The use of piperine-added Curcuma longa L. was effective in the glycaemic and TG control of patients with type 2 diabetes" - [Nutra USA] - See curcumin at Amazon.com and piperine extract at Amazon.com.
• REDUCE-IT: CV Benefit of Icosapent Ethyl Directly Related to EPA Levels - Medscape, 4/2/20 - "The REDUCE-IT trial, reported in 2018, enrolled 8179 patients who had elevated cardiovascular risk already treated with statins. It found that a high dose of icosapent ethyl (4 g daily) reduced the rate of cardiovascular events by 25% over a median of 4.9 years of follow-up ... Prior to REDUCE-IT, icosapent ethyl was approved for the treatment of patients with triglycerides above 500 mg/dL, and it was anticipated that it would bring about benefits to a broader population of patients at cardiovascular risk primarily by lowering triglycerides ... However, the current analysis found that the lion's share of the drug's large cardiovascular benefit is driven by achieved EPA levels, and not the lowering of triglycerides"
• Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association - Circulation. 2019 Aug 19 - "In a 2002 American Heart Association scientific statement, the omega-3 fatty acids (n-3 FAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) were recommended (at a dose of 2-4 g/d) for reducing triglycerides in patients with elevated triglycerides. Since 2002, prescription agents containing EPA+DHA or EPA alone have been approved by the US Food and Drug Administration for treating very high triglycerides; these agents are also widely used for hypertriglyceridemia ... In treatment of very high triglycerides with 4 g/d, EPA+DHA agents reduce triglycerides by ≥30% with concurrent increases in low-density lipoprotein cholesterol, whereas EPA-only did not raise low-density lipoprotein cholesterol in very high triglycerides. When used to treat hypertriglyceridemia, n-3 FAs with EPA+DHA or with EPA-only appear roughly comparable for triglyceride lowering and do not increase low-density lipoprotein cholesterol when used as monotherapy or in combination with a statin. In the largest trials of 4 g/d prescription n-3 FA, non-high-density lipoprotein cholesterol and apolipoprotein B were modestly decreased, indicating reductions in total atherogenic lipoproteins. The use of n-3 FA (4 g/d) for improving atherosclerotic cardiovascular disease risk in patients with hypertriglyceridemia is supported by a 25% reduction in major adverse cardiovascular events in REDUCE-IT (Reduction of Cardiovascular Events With EPA Intervention Trial), a randomized placebo-controlled trial of EPA-only in high-risk patients treated with a statin" - [Nutra USA] - See omega-3 supplements at Amazon.com.
• Effect of Low Dose Docosahexaenoic Acid-Rich Fish Oil on Plasma Lipids and Lipoproteins in Pre-Menopausal Women: A Dose–Response Randomized Placebo-Controlled Trial - Nutrients 2018, 10(10) - "A randomized, double-blind, placebo-controlled trial was conducted, in which 53 healthy pre-menopausal women with mildly elevated plasma TG levels consumed 0, 0.35, 0.7, or 1 g/day n-3 LCPUFA as HiDHA™ tuna oil or placebo (Sunola oil) capsules for 8 weeks. Supplementation with 1 g/day n-3 LCPUFA, but not lower doses, reduced plasma TG by 23% in pre-menopausal women" - [Nutra USA] - See docosahexaenoic acid at Amazon.com.
• Effect of resveratrol supplementation on lipid profile in subjects with dyslipidemia: A randomized double-blind placebo-controlled trial - Nutri, Jul 2018 - "After intervention period, individuals in the resveratrol group showed a significant decrease in total cholesterol (201.4±34.4 vs 220.6±37.4, p=0.04) and triglyceride (133.4±55.3 vs 166.7±68.5, p=0.04) concentrations compared with the placebo group, without significant statistical differences for HDL-C and LDL-C levels" - [Nutra USA] - See resveratrol products at Amazon.com.
• Inulin Improves Postprandial Hypertriglyceridemia by Modulating Gene Expression in the Small Intestine - Nutrients. 2018 Apr 25;10(5) - "Inulin supplementation in western diet-fed mice decreases postprandial serum triglycerides concentration, decreases the mRNA expression levels of Cd36 (fatty acid receptor involved in lipid uptake and sensing) and apolipoprotein C3 (Apoc3, inhibitor of lipoprotein lipase) in the jejunum and increases fecal lipid excretion. In conclusion, inulin improves postprandial hypertriglyceridemia by targeting intestinal lipid metabolism. This work confirms the interest of using inulin supplementation in the management of dyslipidemia linked to obesity and cardiometabolic risk" - [Nutra USA] - See inulin at Amazon.com.
• A Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Assess the Efficacy and Safety of Ethyl-Ester Omega-3 Fatty Acid in Taiwanese Hypertriglyceridemic Patients - J Atheroscler Thromb. 2016 Sep 6 - "Omacor®, a prescription ethyl-ester omega-3 fatty acid for the treatment of hypertriglyceridemia ... After a five-week diet lead in period patients with triglycerides =200-1000 mg/dL were randomized to receive Omacor®, a concentrated preparation of omega-3 eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) in a dose of 1 g twice daily (2 g Omacor®), 2 g twice daily (4 g Omacor®) or placebo, for eight weeks ... the percentage change in triglyceride serum levels in both the Omacor® 4 g/day (－32.1%) and 2 g/day (－29.7%) groups was larger than in the placebo group (－5.4%)" - See fish oil supplements at Amazon.com.
• A systematic review and meta-analysis of the impact of Spirulina supplementation on plasma lipid concentrations - Clin Nutr. 2015 Sep 25 - "This meta-analysis showed a significant effect of supplementation with Spirulina in reducing plasma concentrations of total cholesterol, LDL-C, triglycerides and elevating those of HDL-C" - See Spirulina at Amazon.com.
• Supplementation with two probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032, reduces fasting triglycerides and enhances apolipoprotein A-V levels in non-diabetic subjects with hypertriglyceridemia - Atherosclerosis. 2015 Jun 18 - "After the treatment, the probiotic group showed an 18.3% (P < 0.001) reduction in TGs and increases of 21.1% (P = 0.001) and 15.6% (P < 0.001) in the apo A-V and LDL particle size, respectively. The probiotic group had a significant reduction in TGs (P = 0.040) and increases in the plasma apo A-V (P = 0.003) and LDL particle size (P < 0.001) compared with the placebo group" - See probiotic products at Amazon.com.
• A review of the effect of omega-3 polyunsaturated fatty acids on blood triacylglycerol levels in normolipidemic and borderline hyperlipidemic individuals - Lipids Health Dis. 2015 Jun 6 - "In summary, a 9-26 % reduction in circulating TG was demonstrated in studies where ≥ 4 g/day of n-3 PUFA were consumed from either marine or EPA/DHA-enriched food sources, while a 4-51 % reduction was found in studies where 1-5 g/day of EPA and/or DHA was consumed through supplements"  - See fish oil supplements at Amazon.com.
• The triglyceride-lowering effect of supplementation with dual probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032: Reduction of fasting plasma lysophosphatidylcholines in nondiabetic and hypertriglyceridemic subjects - Nutr Metab Cardiovasc Dis. 2015 May 14 - "After 12 weeks of treatment, the probiotic group displayed a 20% reduction (p = 0.001) in serum TGs and 25% increases (p=0.001) in apolipoprotein A-V (apoA-V). At the 12-week follow-up assessment, the following 11 plasma metabolites were significantly reduced in the probiotic group than the placebo group" - See probiotic products at Amazon.com.
• Fasting Triglycerides Predict CVD Risk in Statin-Treated Patients - Medscape, 5/29/15 - "those with the highest triglyceride levels at baseline (>175 mg/dL) had a significant 61% increased relative risk of cardiovascular events compared with individuals with the lowest triglyceride levels (<80 mg/dL) ... Even in patients with triglycerides in the 130-to-175-mg/dL range, which is at best considered minimally abnormal by current standards, we saw a significant increase in risk in those patients compared with those patients in the lowest quintile ... For the patient with moderately elevated triglycerides, say 150 mg/dL, lifestyle modification—diet, exercise, limiting alcohol intake, controlling existing diabetes, among other things—is first and foremost ... If triglycerides are still elevated, I might have a discussion with the patient regarding the adjunctive use of fish oil" - See fish oil supplements at Amazon.com.
• The effect of vitamin D supplementation on serum lipids in postmenopausal women with diabetes: A randomized controlled trial - Clin Nutr. 2014 Oct 13 - "total of 104 postmenopausal women with type 2 diabetes were randomly assigned in a double-blind manner to 1 of 2 groups taking a daily tablet for 6 months: a group consuming 4000 IU tablets of a vitamin D supplement (vitamin D group n = 52) or a group consuming placebo tablets (placebo group n = 52) ... Our findings revealed no significant changes in low density lipoproteins, high density lipoproteins and total cholesterol concentrations, but did identify a greater decrease in serum triglycerides in the vitamin D group. The average effect of supplementation on the treated group was -34.24 mg/dL (P = 0.021), while the average treatment effect was -31.8 mg/dL" - See vitamin D at Amazon.com.
• The effect of vitamin D supplementation on serum lipids in postmenopausal women with diabetes: A randomized controlled trial - j.clnu.2014.10.002 - "randomly assigned in a double-blind manner to 1 of 2 groups taking a daily tablet for 6 months: a group consuming 4000 IU tablets of a vitamin D supplement (vitamin D group n = 52) or a group consuming placebo tablets (placebo group n = 52) ... did identify a greater decrease in serum triglycerides in the vitamin D group. The average effect of supplementation on the treated group was −34.24 mg/dL (P = 0.021), while the average treatment effect was −31.8 mg/dL (P = 0.023)" - [Nutra USA] - See vitamin D at Amazon.com.
• Lipid-Lowering Effects of Curcumin in Patients with Metabolic Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial - Phytother Res. 2014 Aug 6 - "Sixty-five patients were randomized into two groups; 33 patients taking curcumin extract capsule (630 mg thrice daily) and 32 patients taking a placebo capsule thrice daily for 12 weeks. At 12 weeks after the curcumin extract consumption, the level of high-density lipoprotein cholesterol (HDL-C) significantly increased from 40.96 ± 8.59 to 43.76 ± 2.79 mg/dL (p < 0.05), and the level of low-density lipoprotein cholesterol (LDL) was significantly reduced (120.55 ± 36.81 to 106.51 ± 25.02 mg/dL, p < 0.05). The triglyceride-lowering effect, a reduction of 65 mg/dL, was also found in this study" - See curcumin products at Amazon.com.
• Effects of vitamin D on plasma lipid profiles in statin-treated patients with hypercholesterolemia: A randomized placebo-controlled trial - Clin Nutr. 2014 May 2 - "Patients with hypercholesterolemia were enrolled in this single-center, double-blind, placebo-controlled trial in Beijing (39°54' N). Fifty-six patients were randomly assigned to receive vitamin D (n = 28, 2000 IU/d) or a placebo (n = 28) as an add-on to statin ... At 6 months, the primary end point, a difference in the fall of serum total cholesterol levels between the vitamin D and placebo groups after 6 months of treatment was significant -22.1 mg/dl (95% CI -32.3; -12.2) (p < 0.001). The difference between the groups in the fall of serum triglyceride levels after 6 months of treatment was -28.2 mg/dl (95% CI -48.8; -8.4) (p < 0.001)" - See vitamin D at Amazon.com.
• Supplementation with carnosine decreases plasma triglycerides and modulates atherosclerotic plaque composition in diabetic apo E(-/-) mice - Atherosclerosis. 2014 Feb;232(2):403-9 - "a significant (~23%) lowering of triglyceride levels in the carnosine-supplemented groups ... These data indicate that in a well-established model of diabetes-associated atherosclerosis, prolonged carnosine supplementation enhances plasma levels, and has novel and significant effects on atherosclerotic lesion lipid, collagen and macrophage levels. These data are consistent with greater lesion stability, a key goal in treatment of existing cardiovascular disease. Carnosine supplementation may therefore be of benefit in lowering triglyceride levels and suppressing plaque instability in diabetes-associated atherosclerosis" - See carnosine products at Amazon.com.
• Atorvastatin plus omega-3 fatty acid ethyl ester decreases very-low-density lipoprotein triglyceride production in insulin resistant obese men - Diabetes Obes Metab. 2013 Dec 3 - "In insulin resistant, dyslipidemic, obese men, atorvastatin improves VLDL-TG metabolism by increasing VLDL-TG FCR. The addition of 4 g/day ω-3 FAEE to statin therapy provides further TG-lowering by lowering VLDL-TG PR" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• Blood lipids profile in hyperlipidemic children undergoing different dietary long chain polyunsaturated supplementations: a preliminary clinical trial - Int J Food Sci Nutr. 2013 Nov 14 - "Thirty-six children (8-13 years) were recruited. After an 8-week stabilization period on the Step I diet, they were randomized to additionally receive for a 16-week period one capsule (500 mg) daily of docosahexaenoic acid (DHA) alone or a DHA plus eicosapentaenoic acid (EPA) mixture (45.6% DHA; 41.6% EPA) or wheat germ oil (control). An effect size (as percentage change from baseline) of +8%, -12% and -16% for high-density lipoprotein cholesterol (HDL-C), total cholesterol/HDL-C ratio and triglycerides was observed in children supplemented with DHA, compared to +2%, -8% and -12%, respectively, in children supplemented with DHA plus EPA" - See Jarrow Max DHA at Amazon.com.  Here it is in table form which is easier to see:

  	DHA	DHA + EPA
  HDL	+8%	+2
  Total cholesterol/HDL	-12%	-8%
  Triglycerides	-16%	-12%

• Betaine supplement alleviates hepatic triglyceride accumulation of apolipoprotein E deficient mice via reducing methylation of peroxisomal proliferator-activated receptor alpha promoter - Lipids Health Dis. 2013 Mar 13;12(1):34 - "Our findings indicate that betaine supplement could alleviate hepatic triglyceride accumulation and improve antioxidant capacity by decreasing PPAR alpha promoter methylation and upregulating PPAR alpha and its target genes mRNA expression" - See TMG at Amazon.com.
• Titrating lovaza from 4 to 8 to 12 grams/day in patients with primary hypertriglyceridemia who had triglyceride levels >500 mg/dl despite conventional triglyceride lowering therapy - Lipids Health Dis. 2012 Oct 30;11(1):143 - "With TG >500 mg/dl despite Type V diet, hyperinsulinemia and diabetes control, and fibric acids, Lovaza (4 g/d) was added for 1 month, and if TG remained >500 mg/dl, increased to 8 g/d for 1 month, and then to 12 g/d for 1 month, and subsequently reduced to 4 g/day for 4 months ... Titration of Lovaza from 4 to 8 to 12 g/d safely offers an effective way to lower TG beyond conventional 4 g therapy" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• Effects of omega-3 fatty acids on postprandial triglycerides and monocyte activation - Atherosclerosis. 2012 Sep 13 - "Patients were treated with 4 g n3-FA/day or placebo for 3 weeks in a randomized, placebo-controlled, double-blind, crossover study. Relative postprandial TG increase reached its maximum 4 h after fat intake (185.1 +/- 10.9% of baseline). n3-FA reduced fasting TG from 137.1 +/- 12.9 to 112.2 +/- 8.6 mg/dl (p < 0.05), and maximum ppTG concentrations from 243.6 +/- 24.6 to 205.8 +/- 17.1 mg/dl (p < 0.05), while relative TG increase (192.8 +/- 12.7%) was comparable to placebo" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• Beneficial effects of combined olive oil ingestion and acute exercise on postprandial TAG concentrations in healthy young women - Br J Nutr. 2012 Jan 23:1-7 - "Foods high in monounsaturated fat, such as olive oil, and endurance exercise are both known to independently reduce postprandial TAG concentrations. We examined the combined effects of exercise and dietary fat composition on postprandial TAG concentrations in nine healthy pre-menopausal females (age 26.8 (sd 3.3) years, BMI 22.3 (sd 2.0) kg/m2). Each participant completed four, 2 d trials in a randomised order: (1) butter-no exercise, (2) olive oil-no exercise, (3) butter-exercise, (4) olive oil-exercise. On day 1 of the exercise trials, participants walked or ran on a treadmill for 60 min. On the no-exercise trials, participants rested on day 1. On day 2 of each trial, participants rested and consumed an olive oil meal (saturated fat 15 % and unsaturated fat 85 %) or a butter meal (saturated fat 71 % and unsaturated fat 29 %) for breakfast ... A significant main effect on physical activity (exercise or control) was obtained for plasma TAG concentration (three-way ANOVA, P = 0.043), and the total area under the concentration v. time curve for TAG was 26 % lower on the olive oil-exercise trial (4.40 (sd 0.40) mmol × 6 h/l) than the butter-no exercise trial (5.91 (sd 1.01) mmol × 6 h/l) (one-way ANOVA, P = 0.029). These findings suggest that the combination of exercise and a preference for monounsaturated dietary fat intake in the form of olive oil may be most beneficial for reducing postprandial TAG concentrations"
• Estimating health and economic benefits from using prescription omega-3 Fatty acids in patients with severe hypertriglyceridemia - Am J Cardiol. 2011 Sep 1;108(5):691-7 - "In patients with severe (≥500 mg/dl) hypertriglyceridemia (SHTG), clinical trials have demonstrated that prescription ω-3 fatty acids (P-OM3s) 4 g/day can decrease triglyceride levels by 45% ... Simulation results for the control arm indicated that subjects with SHTG are at about 2 times higher risk for myocardial infarction than those with normal triglyceride levels. Using estimates from previous epidemiologic studies and meta-analyses with OM3s, the model predicted 29% to 36% decreases in various measurements of adverse cardiac events for the intervention arm. The model also predicted a decrease in ischemic stroke of 24% (95% confidence interval 15 to 33)" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• Green tea intake lowers fasting serum total and LDL cholesterol in adults: a meta-analysis of 14 randomized controlled trials - Am J Clin Nutr. 2011 Jun 29 - "We performed a comprehensive literature search to identify relevant trials of green tea beverages and extracts on lipid profiles in adults ... The analysis of eligible studies showed that the administration of green tea beverages or extracts resulted in significant reductions in serum TC and LDL-cholesterol concentrations, but no effect on HDL cholesterol was observed" - See green tea extract at Amazon.com.
• Eicosapentaenoic Acid Ethyl Ester (AMR101) Therapy in Patients With Very High Triglyceride Levels (from the Multi-center, plAcebo-controlled, Randomized, double-blINd, 12-week study with an open-label Extension [MARINE] Trial) - Am J Cardiol. 2011 Jun 15 - "AMR101 is an omega-3 fatty acid agent containing ≥96% eicosapentaenoic acid ethyl ester and no docosahexaenoic acid ... AMR101 4 g/day reduced the placebo-corrected TG levels by 33.1%" - See Mega Twin EPA at Amazon.com.
• Dietary, lifestyle changes can significantly reduce triglycerides - 4/18/11 - "Changes such as substituting healthy, unsaturated dietary fats for saturated ones, engaging in physical activity and losing excess weight can decrease triglycerides by 20 percent to 50 percent ... analyzed more than 500 international studies from the past 30 years to formulate the scientific statement ... Recommended dietary changes for those outside the normal range of triglycerides include limiting: ... added sugar to less than 5 percent to 10 percent of calories consumed -- about 100 calories per day for women and 150 calories per day for men ... fructose from both processed foods and naturally occurring foods -less than 50 to 100 grams per day ... saturated fat to less than 7 percent of total calories ... trans fat to- less than 1 percent of total calories ... alcohol, especially if triglyceride levels are higher greater than 500 mg/dL ... nearly one-third (31 percent) of adults have elevated triglyceride levels (more than 150 mg/dL)"
• Pomegranate Juice Protects Macrophages from Triglyceride Accumulation: Inhibitory Effect on DGAT1 Activity and on Triglyceride Biosynthesis - Ann Nutr Metab. 2011 Jan 6;58(1):1-9 - "pomegranate juice (PJ) ... PJ (0-50 μM) significantly and dose-dependently decreased the triglyceride content and triglyceride biosynthesis rate in J774A.1 macrophages or in C57BL/6 MPM by about 30%. Similarly, punicalagin, the major PJ polyphenol, inhibited the MPM triglyceride biosynthesis rate by 40%. The triglyceride hydrolytic rate, however, was not significantly affected by PJ or punicalagin. The activity of diacylglycerol acyltransferase 1 (DGAT1; the rate-limiting enzyme in triglyceride biosynthesis) was significantly inhibited, by 54%, in C57BL/6 MPM that were treated with 50 μM PJ or punicalagin, with no significant effect on DGAT1 mRNA or protein expression. Both PJ and punicalagin increased (1.7-fold) MPM PON2 mRNA expression, and PON2 was previously shown to inhibit DGAT1 activity. However, the addition of PJ or punicalagin (50 μM) to microsomes from PON2-deficient MPM still resulted in a significant reduction (50-58%) in DGAT1 activity" - See pomegranate at Amazon.com.
• Dose-response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy persons with moderate hypertriglyceridemia - Am J Clin Nutr. 2010 Dec 15 - "effects of 0.85 and 3.4 g EPA+DHA/d ... The higher dose of EPA+DHA lowered triglycerides by 27% compared with placebo (173 +/- 17.5 compared with 237 +/- 17.5 mg/dL; P = 0.002), whereas no effect of the lower dose was observed on lipids. No effects on cholesterol (total, LDL, and HDL), endothelial function [as assessed by flow-mediated dilation, peripheral arterial tonometry/EndoPAT (Itamar Medical Ltd, Caesarea, Israel), or Doppler measures of hyperemia], inflammatory markers (interleukin-1β, interleukin-6, tumor necrosis factor-α, and high-sensitivity C-reactive protein), or the expression of inflammatory cytokine genes in isolated lymphocytes were observed" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• Prospective randomized comparison between omega-3 fatty acid supplements plus simvastatin versus simvastatin alone in Korean patients with mixed dyslipidemia: lipoprotein profiles and heart rate variability - Eur J Clin Nutr. 2010 Sep 29 - "After 6 weeks of drug treatment, triglyceride levels decreased by 41.0% in the combination treatment group and 13.9% in the simvastatin monotherapy group (from 309.2+/-95 mg per 100 ml to 177.7+/-66 versus 294.6+/-78 mg per 100 ml to 238.3+/-84 mg per 100 ml, respectively" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• Effects of myo-inositol supplementation in postmenopausal women with metabolic syndrome: a perspective, randomized, placebo-controlled study - Menopause. 2010 Aug 31 - "Myo-inositol plus diet improved systolic and diastolic blood pressure, HOMA index, cholesterol, and triglyceride serum levels with highly significant differences, compared with the groups treated only with diet and placebo. In the group treated with myo-inositol, a decrease in diastolic blood pressure (-11%), HOMA index (-75%), and serum triglycerides (-20%) and an improvement in high-density lipoprotein cholesterol (22%) were shown ... CONCLUSIONS: Supplementation with myo-inositol may be considered a reliable option in the treatment of metabolic syndrome in postmenopausal women" - Note:  See raysahelian.com/inositol.html  and http://en.wikipedia.org/wiki/Inositol which claim myo-inositol and inositol are the same.  See myo inositol at Amazon.com.
• Astaxanthin’s heart benefits get human data support - Nutra USA, 8/9/10 - "Daily supplements of the carotenoid astaxanthin may improve HDL ‘good’ cholesterol levels in people with mildly abnormal blood lipid levels ... participants receiving the two highest doses experienced significant reductions in their triglyceride levels, of 25 and 24 percent, respectively, compared to baseline. Furthermore, people receiving 6 or 12 mg per day experienced significant increases in their HDL-cholesterol levels of 10 and 15 percent, respectively ... Additionally, adiponectin levels increased in the two highest dose groups, with increases over 20 percent in the 12 mg per day group, and between 15 and 20 percent in the 18 percent group" - See Jarrow Formulas, CarotenALL, Mixed Carotenoid Complex at Amazon.comor astaxanthin products at iHerb.
• Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia - Atherosclerosis. 2010 Apr;209(2):520-3 - "Multiple comparison tests showed that 12 and 18 mg/day doses significantly reduced triglyceride, and 6 and 12 mg doses significantly increased HDL-cholesterol. Serum adiponectin was increased by astaxanthin (12 and 18 mg/day), and changes of adiponectin correlated positively with HDL-cholesterol changes independent of age and BMI" - See Jarrow Formulas, CarotenALL, Mixed Carotenoid Complex at Amazon.comor astaxanthin at Amazon.com.
• Effects of a 1-year dietary intervention with n-3 polyunsaturated fatty acid-enriched olive oil on non-alcoholic fatty liver disease patients: a preliminary study - Int J Food Sci Nutr. 2010 May 13 - "Consumption of olive oil enriched with n-3 PUFA demonstrated a significant improvement of liver echo-texture and of the Doppler Perfusion Index after 12 months (after: 0.19 +/- 0.02 vs. pre: 0.15 +/- 0.03; P < 0.05), whereas no significant changes were seen at the end of follow-up in controls. Moreover, patients who consumed the olive oil enriched with n-3 PUFA showed a significant amelioration of liver enzymes, and of triglycerides (post: 132.8 +/- 63.7 vs. pre: 164.5 +/- 85.5 mg/dl; P = 0.04) in a general linear model adjusted for age and gender. Interestingly, patients reported to have a significant increase of adiponectin levels (post: 1,487.9 +/- 96.7 vs. pre: 1,143 +/- 24.8 mug/ml; P = 0.04)"
• Successful Treatment of Severe Hypertriglyceridemia with a Formula Diet Rich in Omega-3 Fatty Acids and Medium-Chain Triglycerides - Ann Nutr Metab. 2010 Feb 12;56(3):170-175 - "Patients with highly increased plasma triglyceride levels are at risk of developing serious complications such as pancreatitis, coronary heart disease and stroke. Therefore it is important to rapidly decrease plasma triglyceride levels. A sufficient control of triglyceride levels with drugs like fibrates, statins or nicotinic acid can usually only be attained after a couple of weeks. Plasma exchange appears to be a fast but expensive method to reduce triglyceride levels. In this study we describe the use of a new omega-3 fatty acid and medium-chain triglyceride-rich formula diet as a therapeutic concept to reduce plasma triglyceride levels fast and effectively ... Thirty-two patients with severe hypertriglyceridemia were treated with the especially composed formula diet for a period of 7 days. Results: Within this period of time, plasma triglycerides decreased from 1,601 (402-4,555) to 554 (142-2,382) mg/dl (p < 0.05). Total cholesterol levels were reduced from 417 (211-841) to 287 (165-457) mg/dl (p < 0.001). Fasting glucose and uric acid levels also slightly decreased (-8%; -12%). The formula diet as a 1-week treatment was well tolerated and accepted by the patients" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• Dietary supplementation of n-3 PUFA reduces weight gain and improves postprandial lipaemia and the associated inflammatory response in the obese JCR:LA-cp rat - Diabetes Obes Metab. 2009 Nov 16 - "n-3 PUFA treatment resulted in a significant improvement (i.e. decrease) in the postprandial response for triglyceride (45%) (p < 0.05), apoB48 (45%) (p < 0.03) and LBP (33%) (p < 0.05) compared to controls (measured as area under the clearance curve). In contrast, we observed a significant elevation in postprandial haptoglobin (165%) (p < 0.001) in obese rats supplemented with 10% n-3 PUFA. Treatment with 5% n-3 PUFA in the JCR:LA-cp obese animals resulted in a complementary decrease in total body weight gain (6%) (p < 0.001) and an increase (i.e. improvement) in adiponectin (33%) (p < 0.05) compared to controls, without a concomitant reduction in food intake" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• The effects of [omega]3 fatty acids and coenzyme Q10 on blood pressure and heart rate in chronic kidney disease: a randomized controlled trial - J Hypertens. 2009 Sep;27(9):1863-72 - "patients were randomized to either omega3FA (4 g), CoQ (200 mg), both supplements or control (4 g), daily for 8 weeks ... omega3FA, but not CoQ, reduced 24-h ambulatory heart rate (P<0.0001) and blood pressure ... omega3FA reduced triglycerides 24%" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• Omega-3 fatty acid supplements improve the cardiovascular risk profile of subjects with metabolic syndrome, including markers of inflammation and auto-immunity - Acta Cardiol. 2009 Jun;64(3):321-7 - "were given 1 gram of fish oil as a single capsule, containing 180 mg eicosapentaenoic acid and 120 mg docosahexaenoic acid daily for 6 months. Control subjects did not receive any supplementation over the same period. RESULTS: The study was completed by 47 subjects in the intervention group and 42 subjects in the control group. Treatment with omega 3 supplements was associated with a significant fall in body weight (P < 0.05), systolic blood pressures (P < 0.05), serum low density lipoprotein cholesterol (P < 0.05), and total cholesterol (P < 0.05), triglycerides (P < 0.05), high-sensitivity C-reactive protein (hs-CRP) (P < 0.01), and Hsp27 antibody titres (P < 0.05). No significant changes were observed in the control group. CONCLUSION: It appears that omega 3 improves the cardiovascular risk profile of subjects with metabolic syndrome, having effects on weight, systolic blood pressure, lipid profile and markers of inflammation and autoimmunity" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• Quercetin inhibits fatty acid and triacylglycerol synthesis in rat-liver cells - Eur J Clin Invest. 2009 Jun 8 - "In hepatocytes from normal rats, the quercetin-induced decrease in both de novo fatty acid and TAG synthesis, with a consequent reduction in VLDL-TAG formation, may represent a potential mechanism contributing to the reported hypotriacylglycerolemic effect of quercetin" - See quercetin at Amazon.com.
• Triglycerides Too High? - Dr. Weil, 2/19/09
• New Approach Discovered To Lowering Triglycerides - Science Daily, 3/30/09 - "In the lab animals, supplements of lipoic acid lowered triglyceride levels up to 60 percent ... supplements of lipoic acid appeared to affect triglyceride levels through two pathways. After eating, lipoic acid supplementation increased the rate of disappearance of triglycerides in the bloodstream. And supplements also reduced the genetic expression of enzymes in the liver that synthesize triglycerides ... Lipoic acid supplements have in various studies been shown to be an appetite suppressant ... The amount of lipoic acid supplementation used in these laboratory experiments would equate to about two grams per day for a 150-pound person" - See alpha lipoic acid at Amazon.com.
• Late Bedtimes Linked to Heart Disease - WebMD, 3/30/09 - "The fewer hours a man slept each night, the higher his BMI, blood pressure, and triglyceride levels"
• Trans-10, cis-12-conjugated linoleic acid reduces the hepatic triacylglycerol content and the leptin mRNA level in adipose tissue in obese Zucker fa/fa rats - Br J Nutr. 2009 Mar 19:1-13 - "Conjugated linoleic acid (CLA) isomers have been reported to reduce body weight and beneficially affect glucose metabolism in animals, but the results are inconsistent and seem to depend on animal model and type of CLA isomer. In the present study, feeding male Zucker fa/fa rats diets supplemented with 1 % trans-10, cis-12-CLA for 10 d reduced the liver TAG content without improving the overall adiposity, and enhanced hepatic mitochondrial and peroxisomal beta-oxidation ... The present results suggest that dietary supplementation with trans-10, cis-12-CLA may increase the catabolism of lipids in liver and adipose tissue. Moreover, we provide new data suggesting that trans-10, cis-12-CLA modulates the expression of resistin and adiponectin inversely in adipose tissue. Hence, the present results suggest that trans-10, cis-12-CLA may have some beneficial effects on lipid metabolism and adiposity but possibly reduces insulin sensitivity" - See conjugated linoleic acid at Amazon.com.
• Resveratrol inhibits fatty acid and triacylglycerol synthesis in rat hepatocytes - Eur J Clin Invest. 2009 Mar;39(3):211-8 - "Results here reported show that in isolated hepatocytes from normal rats a resveratrol-induced short-term inhibition of fatty acid and triacylglycerol synthesis occurs. This finding may represent a potential mechanism contributing to the reported hypolipidemic effect of resveratrol" - See resveratrol products at Amazon.com.
• Dietary Green Tea Extract Lowers Plasma and Hepatic Triglyceride and Decreases the Expression of Sterol Regulatory Element-Binding Protein-1c mRNA and Its Responsive Genes in Fructose-Fed Ovariectomized Rats - J Nutr. 2009 Feb 4 - "Fructose elevated plasma TG and cholesterol compared with the S group. GT at 0.5 and 1.0% markedly lowered plasma and liver TG. Fructose increased the expression of SREBP-1c, fatty acid synthase, and stearoyl-CoA desaturase 1 mRNAs in the liver, whereas GT decreased the expression of these lipogenic genes. Similarly, fructose increased the abundance of hepatic 3-hydroxy-3-methyl-glutaryl-CoA reductase mRNA, whereas GT significantly decreased its expression ... the lipid-lowering effect of GT is mediated partly by its inhibition of hepatic lipogenesis involving SREBP-1c and its responsive genes without affecting lipoprotein assembly" - See green tea extract at Amazon.com.
• Fish Oil, Red Yeast Rice Cut Cholesterol - WebMD, 7/23/08 - "We followed them for a three-month period ... The LDL declined 42% in the supplement group and 39% in the Zocor group ... The supplement group also lost an average of 10 pounds in 12 weeks, but there was no significant weight loss in the medication group. Triglyceride levels, while on average normal in both groups at the start, decreased by 29% in the supplement group but just 9.3% in the medication group -- a significant difference" - See red yeast rice at Amazon.com and Mega Twin EPA at Amazon.com.
• Omega-3 fatty acid concentrates in the treatment of moderate hypertriglyceridemia - Expert Opin Pharmacother. 2008 May;9(7):1237-48 - "Prescription omega-3 fatty acid concentrates (P-OM3) are indicated for use in people with very high triglycerides ... P-OM3 are effective in reducing triglycerides by approximately 30% in this population" - See Mega Twin EPA at Amazon.com.
• Omega-3 fatty acid containing diets decrease plasma triglyceride concentrations in mice by reducing endogenous triglyceride synthesis and enhancing the blood clearance of triglyceride-rich particles - Clin Nutr. 2008 Mar 22 - "Levels of hepatic TG and apoB synthesis were 30-50% and 42% lower in mice fed with the fish oil diet compared to the other three diets. In addition, compared to soy oil diet, fish oil feeding significantly increased blood clearance of chylomicron-like lipid emulsions by 21-26%" - See Mega Twin EPA at Amazon.com.
• Omega-3 Fatty Acids May Be Useful for Cardioprotection - Medscape, 3/18/08 - "To date, the strongest evidence showing a CV benefit from omega-3 fatty acid intake derives from 3 large controlled trials in which a total of 32,000 participants were randomized to a control group or to receive omega-3 fatty acid supplements containing DHA and EPA. In these trials, the supplemented group had a 19% to 45% reduction in CV events vs the control group ... Patients with hypertriglyceridemia should consume 3 to 4 g/day of DHA and EPA, which can lower triglyceride levels by 20% to 50%" - See Mega Twin EPA at iHerb.
• Prescription omega-3 fatty acids and their lipid effects: physiologic mechanisms of action and clinical implications - Expert Rev Cardiovasc Ther. 2008 Mar;6(3):391-409 - "Hypertriglyceridemia is a risk factor for atherosclerotic coronary heart disease. Very high triglyceride (TG) levels (>/=500 mg/dl [5.65 mmol/l]) increase the risk of pancreatitis. One therapeutic option to lower TG levels is omega-3 fatty acids, which are derived from the oil of fish and other seafood. The American Heart Association has acknowledged that fish oils may decrease dysrhythmias, decrease sudden death, decrease the rate of atherosclerosis and slightly lower blood pressure, and has recommended fish consumption or fish oil supplementation as a therapeutic strategy to reduce cardiovascular disease. A prescription omega-3-acid ethyl esters (P-OM3) preparation has been available in many European nations for at least a decade, and was approved by the US FDA in 2004 to reduce very high TG levels (>/=500 mg/dl [5.65 mmol/l]). Mechanistically, most evidence suggests that omega-3 fatty acids reduce the synthesis and secretion of very-low-density lipoprotein (VLDL) particles, and increase TG removal from VLDL and chylomicron particles through the upregulation of enzymes, such as lipoprotein lipase. Omega-3 fatty acids differ mechanistically from other lipid-altering drugs, which helps to explain why therapies such as P-OM3 have complementary mechanisms of action and, thus, complementary lipid benefits when administered with statins" - See Mega Twin EPA at Amazon.com.
• Omega3 Fatty acids for cardioprotection - Mayo Clin Proc. 2008 Mar;83(3):324-32 - "The most compelling evidence for the cardiovascular benefit provided by omega-3 fatty acids comes from 3 large controlled trials of 32,000 participants randomized to receive omega-3 fatty acid supplements containing docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) or to act as controls. These trials showed reductions in cardiovascular events of 19% to 45%. These findings suggest that intake of omega-3 fatty acids, whether from dietary sources or fish oil supplements, should be increased, especially in those with or at risk for coronary artery disease. Patients should consume both DHA and EPA. The target DHA and EPA consumption levels are about 1 g/d for those with known coronary artery disease and at least 500 mg/d for those without disease. Patients with hypertriglyceridemia benefit from treatment with 3 to 4 g/d of DHA and EPA, a dosage that lowers triglyceride levels by 20% to 50%. Although 2 meals of oily fish per week can provide 400 to 500 mg/d of DHA and EPA, secondary prevention patients and those with hypertriglyceridemia must use fish oil supplements if they are to reach 1 g/d and 3 to 4 g/d of DHA and EPA, respectively" - See Mega Twin EPA at iHerb and Jarrow Max DHA at Amazon.com.  I take both because the percentage of omega-3 (EPA and DHA) is very low in other supplements.  I don't know what the rest of that oil is but your not saving anything by getting supplements with a low percentage.  Just do the math plus if the rest of the oil is an omega-6 you're not helping the omega-6/omega-3 ratio.
• Resveratrol attenuates the expression of HMG-CoA reductase mRNA in hamsters - Biochem Biophys Res Commun. 2007 Dec 28 - "The concentrations of serum total cholesterol and triglyceride were significantly lower in the resveratrol-fed group than in the control group. The resveratrol contained diet significantly decreased Apo B, Lp(a), and cholesterol-ester-transport protein (CETP) concentrations, but increased Apo A-I levels and the Apo A-I/Apo B ratio. The contents of cholesterol and triglyceride in hepatic tissue were significantly lower in the resveratrol group than in the control group. Real-time PCR analysis revealed that HMGR mRNA expression was significantly lower in the resveratrol group than in the control group" - See resveratrol products at Amazon.com.
• Combination Niacin-Laropiprant Plus Simvastatin Reduces Cholesterol by Almost 50% - Doctor's Guide, 11/6/07 - "When patients with dyslipidemia added simvastatin to their experimental combination of extended-release niacin and laropiprant -- a novel anti-flushing agent -- they reported reductions in low density lipoprotein cholesterol (LDL-C) of as much as 48% from baseline ... high density liopoprotein cholesterol (HDL-C) was increased by 28% and triglycerides decreased by 33%"
• Role of prescription omega-3 Fatty acids in the treatment of hypertriglyceridemia - Pharmacotherapy. 2007 May;27(5):715-28 - "In patients with triglyceride levels above 500 mg/dl, approximately 4 g/day of EPA and DHA reduces triglyceride levels 45% and very low-density lipoprotein cholesterol levels by more than 50%" - See Mega Twin EPA at Amazon.com or Jarrow Max DHA at Amazon.com.
• Effect of omega-3 Fatty Acid supplementation on the arachidonic Acid:eicosapentaenoic Acid ratio - Pharmacotherapy. 2007 May;27(5):633-8 - "Triglyceride levels were not reduced in patients with CAD but were significantly decreased in healthy subjects (by 20% decrease with omega-3 fatty acids 1.5 g/day and by 32% decrease with 3 g/day)"
• Effect of combination lipid-modifying therapy on the triglyceride lowering effect of fish oil - Am J Med Sci. 2007 Mar;333(3):168-72 - "Fish oil effectively reduces plasma triglyceride levels when administered with concomitant lipid medications"
• DHA alone can lower triglycerides, says study - Nutra USA, 2/7/07 - "Subjects were randomized to either 1000mg of DHA or 1252 mg of DHA + EPA for eight weeks ... triglycerides were lowered an average of 21.8 per cent in the DHA group and 18.3 per cent in the DHA + EPA group" - See Jarrow Max DHA at Amazon.com.
• The triglyceride-lowering effects of a modest dose of docosahexaenoic acid alone versus in combination with low dose eicosapentaenoic acid in patients with coronary artery disease and elevated triglycerides - J Am Coll Nutr. 2006 Dec;25(6):480-5 - "randomized to either 1000 mg of DHA or 1252 mg of DHA + EPA for eight weeks ... Triglycerides decreased by an average of 21.8% in the DHA group (p < 0.001) and 18.3% in the DHA + EPA group (p < 0.001). The difference between groups was not significant. A greater proportion of subjects in the DHA group achieved triglyceride goal (less than 150 mg/dL) compared to the DHA + EPA group (24.6% versus 10.2%, p < 0.05)" - See Jarrow Max DHA at Amazon.com or Mega Twin EPA at Amazon.com.
• Hypertriglyceridemia - Medscape, 6/1/06 - "Omega-3 fatty acids (4 g per day) will reduce triglyceride levels by 30% ... ER niacin has been shown to lower the triglyceride level by ~25% and raise the HDL level by almost 30%"
• In search of those omega-3 fatty acids -  San Diego Union-Tribune, 3/7/06 - "Fish oils from supplements or dietary sources can reduce triglycerides by 20 percent to 50 percent ... Studies have used triglyceride-lowering doses of 1 to 4 grams (1,000 mg to 4,000 mg) daily"
• Omega-3 Fatty Acids in the Management of Hypertriglyceridemia: New Findings and Formulations - Continuing Medical Education (CME):Princeton Media Associates, exp. 10/29/06 - "To lower TG levels, the dose of omega-3 therapy is ~4 g of EPA + DHA per day" - See Mega Twin EPA at Amazon.com.
• Fish Oil Supplements Improve Lipid Risk Factors in Obese Children - Medscape, 11/14/05 - "given 3 g of a daily fish oil supplement ... After 12 weeks, the researchers found that triglyceride levels in the control group did not significantly differ from baseline. In contrast, triglyceride levels in children treated with fish oil significantly decreased. However, differences in other lipid measures were not statistically significant" - See Mega Twin EPA at iHerb.
• Omega-3 Fatty Acids: Recommendations for Therapeutics and Prevention - Medscape, 10/19/05 - "Supplementation of 4 g EPA/DHA per day for 6 weeks resulted in a 20% TG decline in mildly hyperlipidemic middle-aged men"  - See Mega Twin EPA at iHerb.
• Plasma Triglyceride and the Risk for Vascular Disease - Medscape, 9/19/05 - "omega-3 fatty acid therapy, particularly when administered in moderate doses[42] on a scale matching natural fish consumption, significantly reduces plasma triglyceride"
• Women and Omega-3 Fatty Acids - Obstet Gynecol Surv. 2004 Oct;59(10):722-730 - "because elevated triglyceride levels are associated with cardiovascular disease, especially in women; and because omega-3 FA have powerful effects on triglycerides, women in particular gain from an increased intake of these fatty acids. This is especially important in women receiving hormone therapy, which can increase triglyceride levels." - See Mega Twin EPA at iHerb.
• Increased n-6 polyunsaturated fatty acids do not attenuate the effects of long-chain n-3 polyunsaturated fatty acids on insulin sensitivity or triacylglycerol reduction in Indian Asians - Am J Clin Nutr. 2004 Jun;79(6):983-991 - "were supplemented with 4.0 g fish oil/d (2.5 g eicosapentaenoic acid + docosahexaenoic acid) ... After the 6-wk period of fish oil supplementation, fasting and postprandial plasma triacylglycerol concentrations decreased significantly" - See Mega Twin EPA at iHerb.
• Soy protein reduces triglyceride levels and triglyceride fatty acid fractional synthesis rate in hypercholesterolemic subjects - Atherosclerosis. 2004 Apr;173(2):269-75 - "Soy protein reduced TG by 12.4% ( [Formula: see text] ) ... compared to animal protein"
• Dietary linolenic acid is inversely associated with plasma triacylglycerol: the National Heart, Lung, and Blood Institute Family Heart Study - Am J of Clin Nutr, Vol. 78, No. 6, 1098-1102, 12/03 - "We used generalized linear models to estimate adjusted mean triacylglycerol concentrations according to categories of total dietary linolenic acid (alpha- and gamma-linolenic acid) intake ... Consumption of total linolenic acid is inversely related to plasma triacylglycerol concentrations in both white men and white women. This suggests a pathway by which dietary linolenic acid might reduce cardiovascular disease risk" - The way I understand it, by linolenic acid they are talking about alpha (omega-3) and gamma (GLA, an omega-6). - Ben
• Eating Fish Lowers Heart Disease Risk in Women With Diabetes - WebMD, 3/31/03 - "It is believed that omega-3 fatty acids abundant in the fat of many fish reduces the risk of heart disease by lowering triglyceride levels, improving blood vessel function, and reducing blood-clot formation"
• Lipid Benefits With Monounsaturated-Fatty-Acids Diet In Healthy People - Doctor's Guide, 3/14/03 - "A moderate supplementation of long-chain n-3 fatty acids in healthy individuals reduces both fasting and post-prandial triacylglycerol concentrations but increases LDL cholesterol, irrespective of the type of diet"
• Differential effects of saturated and monounsaturated fats on postprandial lipemia and glucagon-like peptide 1 responses in patients with type 2 diabetes - Am J Clin Nutr 2003 Mar;77(3):605-11 - "Olive oil induced lower triacylglycerol concentrations and higher HDL-cholesterol concentrations than did butter, without eliciting significant changes in glucose, insulin, or fatty acids" - Olive oil is 76% omega-9.
• I take Lopid (gemfibrozil) to lower my blood triglyceride and cholesterol levels, but I am concerned about the side effects. Is there anything natural that I can take instead? - Dr. Murray - "Pantethine has been shown to significantly reduce serum triglyceride (-32%), total cholesterol (-19%), and LDL-cholesterol (-21%) levels while increasing HDL-cholesterol (+23%) levels in several clinical trials"
• Randomized controlled trial of the effect of n–3 fatty acid supplementation on the metabolism of apolipoprotein B-100 and chylomicron remnants in men with visceral obesity1 - Am. J. of Clin. Nutr., 2/03 - "randomly assigned to receive either fish oil capsules (4 g/d, consisting of 45% eicosapentaenoic acid and 39% docosahexaenoic acid as ethyl esters) or matching placebo ... Fish oil supplementation significantly (P < 0.05) lowered plasma concentrations of triacylglycerols (-18%) and VLDL apo B (-20%) and the hepatic secretion of VLDL apo B (-29%) compared with placebo" - Doing the math, 45% of 4 grams equals 1,800 mg of EPA,  39% of 4 grams equals 1,560 mg of DHA.  Three Mega Twin EPA at iHerb plus three Jarrow Max DHA at Amazon.com (the two strongest formulas I know) would be 2,100 mg EPA and 1,570 mg DHA.
• Chromium For Insulin Function - Functional Foods & Nutraceuticals, 1/03 - "28 patients received 200mcg/day chromium picolinate for two months. Although there was no change seen in HDL or LDL cholesterol, triglyceride levels dropped 17.4 per cent"
• Ispaghula Husk [psyllium] Nearly As Effective As Simvastatin For Hyperlipidemia - Doctor's Guide, 12/24/02 - "One group received 3.5 grams of ispaghula husk twice a day and the second group received 20 milligrams of simvastatin each day ... total cholesterol decreased by 15.8 percent and low-density lipoprotein (LDL) cholesterol decreased by 22.97 percent among patients taking ispaghula husk ... Triglycerides decreased by 20.89 percent and high-density lipoprotein (HDL) cholesterol increased by 10.69 percent in these patients ... Among patients taking simvastatin, total cholesterol decreased by 24.15 percent, LDL cholesterol decreased by 36.08 percent, triglycerides decreased by 20.47 percent and HDL cholesterol increased by 11.4 percent" - I've got that. See psyllium husk at Amazon.com.  3.5 grams is about one wafer (3.4 grams psyllium/wafer).  Plus 24 wafers runs about $4.49 versus about $116 for 30 of the 20 mg simvastatin.
• Atkins diet good for cholesterol - USA Today, 11/18/02 - "After six months, the people on the Atkins diet had lost an average of 31 pounds, compared with 20 pounds on the AHA diet, and more people stuck with the Atkins regimen ... Total cholesterol fell slightly in both groups. However, those on the Atkins diet had an 11% increase in HDL, the good cholesterol, and a 49% drop in triglycerides. On the AHA diet, HDL was unchanged, and triglycerides dropped 22%. High triglycerides may raise the risk of heart disease" - That may be true but what about a diet devoid of anti-oxidants making you old before your time.  Plus, how much of that extra 11 pounds was water loss? - Ben
• Silybin-Beta-Cyclodextrin Reduces Glucose, Triglyceride Levels In Diabetes With Liver Disease - Doctor's Guide, 11/12/02 - "Fasting blood glucose levels decreased by 14.7 percent from baseline in patients receiving silybin-beta-cyclodextrin ... Plasma triglycerides concentrations dropped from a mean 186 to 111 mg/dl at six months in those that received silybin-beta-cyclodextrin" - See iHerb silymarin products.
• Fish Oil May Augment Atorvastatin As Treatment For Dyslipidemia In Obese, Insulin-Resistant Men - Doctor's Guide, 8/7/02 - "fish oils significantly decreased plasma levels of triglycerides and very low density lipoprotein-apoB, decreased the very low density lipoprotein-apoB secretion rate" - See Mega Twin EPA at iHerb.
• Omega-3 Fatty Acids May Prevent Heart Disease By Improving Arterial Elasticity - Intelihealth, 7/25/02 - "Both omega-3 fatty acid supplement groups experienced significant declines in plasma total triacylglycerol concentrations"
• Omega 3: Implications in human health and disease - PowerPak (39 page CME course for Registered Dietitians), exp. 8/1/03 - "A substantial body of evidence supports the use of fish oil in the treatment of hypertriglyceridemia.130 In normolipidemic subjects, daily dosages of 2-25 g of omega 3 fatty acids produced decreases in triglyceride concentrations of 20-60%. In patients with hypertriglyceridemia, decreases of up to 81% have been reported" - See Mega Twin EPA at iHerb.
• Rice Bran Lowers Diabetic Blood Sugar - WebMD, 4/10/02 - "Rice bran was able to lower blood glucose by up to 30% in a small group of patients with type 1 or 2 diabetes ... also found that patients with elevated cholesterol who consumed 20 grams per day of stabilized rice bran lowered their total serum cholesterol and triglyceride levels between 5% and 15%"
• question regarding your new cholesterol-lowering supplement, Policosanol - Life Extension Magazine, 11/01 - "Studies show that niacin (B3) in doses of 1.5 grams to 3 grams lower triglycerides levels and raise HDL concentrations. Those who tolerated higher doses of niacin (nicotinic acid) showed even more improvement in lipid levels. Some people taking just 1000 mg of flush-free niacin see an elevation in beneficial HDL. Green tea also has been shown to elevate levels of HDL while lowering serum triglyceride levels. In the Journal of Molecular Cell Biochemistry, curcumin has been demonstrated, in vivo, to decrease triglycerides and increase HDL. In a study published in 1989 by the Journal of Associated Physicians-India, 125 patients receiving gugulipid showed a drop of 16.8% in triglycerides, and a 60% increase in HDL cholesterol within three to four weeks. Make sure you are taking at least six Mega EPA fish oil capsules daily, as low dose fish oil may not adequately suppress triglycerides. Finally, there are some lifestyle changes you may wish to consider. If you are overweight, weight loss would be recommended, as it would help to lower triglycerides and raise HDL. Also, try reducing carbohydrates, which can raise triglycerides"
• Product Review: Omega-3 Fatty Acids (EPA and DHA) from Fish/Marine Oils - ConsumerLabs.com, 11/20/01 - "It's been discovered that EPA and DHA may help prevent heart disease and atherosclerosis by lowering triglyceride levels, raising HDL ("good") cholesterol and, possibly "thinning" the blood ... By decreasing inflammation, EPA and DHA can also reduce the pain of rheumatoid arthritis ... Fish oils may also be useful in treating a host of conditions including bipolar (manic-depressive) disorder, Raynaud's phenomenon (abnormal sensitivity of hands and feet to cold), lupus, IgA nephropathy, kidney stones, chronic fatigue syndrome, Crohn's disease, cystic fibrosis, and ulcerative colitis ... EPA specifically may be helpful for schizophrenia, while DHA may be more helpful in reducing high blood pressure ... DHA may be helpful in the treatment of disorders such as attention deficit disorders, dyslexia, and cognitive impairment and dementia ... experts now believe that the American diet contains too little omega-3 fatty acids and too much omega-6 fatty acids"
• A Fish Story - Nutrition Science News, 4/01 - "daily consumption of very low daily doses of EPA/DHA (120 mg/180 mg, about one standard fish oil capsule) in an enriched milk led to a 19 percent decrease in blood triglycerides and a 19 percent increase in HDL cholesterol after six weeks ... It is unclear whether EPA is superior to DHA, although EPA has proven more potent in relaxing cow coronary arteries and producing the vasodilator gas, nitric oxide, in vitro"
• Fish Oil - The Natural Pharmacist - "Subsequent investigation found that the omega-3 fatty acids found in fish oil can lower blood triglyceride levels, "thin" the blood, and also decrease inflammation in various parts of the body."
• Niacin Reduces Triglycerides, Increases Good Cholesterol In Diabetics - Doctor's Guide, 3/20/01 - "There had been concern that niacin use in diabetic patients might increase blood sugar levels ... but we didn't see that in our study ... Patients were randomised to receive placebo, 1,000 mg of niacin or 1,500 mg of prescription niacin ... Patients taking the active agent increased high-density lipoprotein (HDL) cholesterol by 20 to 24 percent compared with a 4 percent increase among the placebo patients. At the same time, triglycerides were reduced 15 to 29 percent in the patients on niacin compared with a 5 percent reduction among patients taking placebo"
• Evaluation of the Antihyperlipidemic Properties of Dietary Supplements - Medscape, 4/1/01 - "[omega]-3 Fatty Acids ... Triglyceride concentrations decreased by 25% in subjects with normal triglyceride concentrations (< 177 mg/dl) and by 34% in those with elevated concentrations"
• Evaluation of the Antihyperlipidemic Properties of Dietary Supplements - Medscape, 4/1/01 - "After 24 weeks of gugulipid treatment, total cholesterol levels decreased by 25.2 mg/dl, compared with a 7.6 mg/dl increase in the placebo group (p<0.01). The LDL was 16.9 mg/dl lower and 4.0 mg/dl higher, respectively ... In addition, a significant reduction in triglycerides was seen in the gugulipid-treated arm compared with placebo (-18 vs +5.5 mg/dl"
• Using Creatine For More Than Muscles - Nutrition Science News, 10/99 - "A variety of published and unpublished research shows creatine may decrease tumor growth, increase body mass, decrease blood glucose, reduce triglycerides and cholesterol, extend exercise endurance in congestive heart failure patients, and even alter metabolism in people with neurodegenerative diseases such as Alzheimer's and Lou Gehrig's diseases"
• Green Tea Lowers Cholesterol - Nutrition Science News, 10/99
• Chromium Steels the Body Against Diabetes - Nutrition Science News, 2/99 - "The chromium treatment significantly lowered triglycerides"

Other News:

• Triglycerides are a predictive factor for arterial stiffness: a community-based 4.8-year prospective study - Lipids Health Dis. 2016 May 18;15(1):97 - "Lower triglyceride levels were significantly associated with decreases in carotid-femoral PWV, indicating that achieving low TG levels may be an additional therapeutic consideration in subjects with atherosclerotic disease"
• Triglycerides Predict Ten-Years All-Cause Mortality in T2DM - Medscape, 12/26/14 - "mean triglycerides levels during follow-up (III vs I tertile: HR:1.87; IC95%: 1.12–3.12) and lipid-lowering treatment (HR:0.56; IC95%: 0.35–0.90) were significantly associated with all-cause mortality, independent of confounding factors such as mean values of LDL-C, HDL-C, HbA1c, blood pressure, BMI, fasting glucose, and antihypertensive and antidiabetic treatment"
• Effects of blood triglycerides on cardiovascular and all-cause mortality: a systematic review and meta-analysis of 61 prospective studies - Lipids Health Dis. 2013 Oct 29;12(1):159 - "We identified 61 eligible studies, containing 17,018 CVDs deaths in 726,030 participants and 58,419 all-cause deaths in 330,566 participants. Twelve and fourteen studies, respectively, reported the effects estimates of CVDs and total mortality by TG categories. Compared to the referent (90--149 mg/dL), the pooled RRs (95% CI) of CVDs mortality for the lowest (< 90 mg/dL), borderline-high (150--199 mg/dL), and high TG (>= 200 mg/dL) groups were 0.83 (0.75 to 0.93), 1.15 (1.03 to 1.29), and 1.25 (1.05 to 1.50); for total mortality they were 0.94 (0.85 to 1.03), 1.09 (1.02 to 1.17), and 1.20 (1.04 to 1.38), respectively. The risks of CVDs and all-cause deaths were increased by 13% and 12% (p < 0.001) per 1-mmol/L TG increment in twenty-two and twenty-two studies reported RRs per unit TG, respectively"
• Relationship between dyslipidaemia and semen quality and serum sex hormone levels: an infertility study of 167 Japanese patients - Andrologia. 2012 Dec 22 - "serum triglyceride (TG) ... There was no significant relationship between serum TG levels and sperm concentration or motility; however, the serum TG level was positively associated with the sperm morphological traits. Furthermore, the serum levels of glutamic oxaloacetic transaminase and glutamic pyruvic transaminase were associated with the serum TG levels. By contrast, a negative relationship between serum testosterone and TG levels was discovered"
• Disrupted circadian rhythm may cause triglycerides to rise - Science Daily, 8/3/10
• Study: Too Much Sugar Increases Heart Risks - Time Magazine, 4/21/10 - "Compared with people consuming less than 5% of their daily calories in added sugar, those in the highest consumption group — who got 25% or more of their daily calories in added sugar — were twice as likely to have low levels of HDL cholesterol, the beneficial lipid that mops up artery-clogging LDL cholesterol. According to government health guidelines, HDL levels below 50 mg/dL for women and 40 mg/dL for men are considered low; 43% of the highest sugar consumers recorded low HDL, while only 22% of the lowest sugar consumers did ... People eating the most added sugar also recorded the highest triglyceride levels ... Low HDL and high triglyceride levels are two of the primary risk factors for heart disease"
• A high normal TSH is associated with the metabolic syndrome - Clin Endocrinol (Oxf). 2009 Sep 10 - "Subjects with a TSH in the upper normal range (2.5 to 4.5 mU/l, n = 119) had a significantly higher BMI (30.47 +/- 0.57 vs. 28.74 +/- 0.18 kg/m(2), p = 0.001) and higher fasting triglycerides (1.583 +/- 0.082 vs. 1.422 +/- 0.024 mmol/l, p = 0.023), and their likeliness for fulfilling the criteria of the MS was 1.7-fold increased"
• Fat In The Liver -- Not The Belly -- May Be A Better Marker For Disease Risk - Science Daily, 8/25/09 - "Having too much liver fat is known as nonalcoholic fatty liver disease ... when fat collects in the liver, people experience serious metabolic problems such as insulin resistance, which affects the body's ability to metabolize sugar. They also have increases in production of fat particles in the liver that are secreted into the bloodstream and increase the level of triglycerides"
• Triglycerides Implicated in Diabetic Neuropathy - Doctor's Guide, 5/22/09
• High Triglyceride Levels Common, Often Untreated Among Americans - Science Daily, 3/23/09
• Fructose-sweetened Drinks Increase Nonfasting Triglycerides In Obese Adults - Science Daily, 2/12/09 - "Obese people who drink fructose-sweetened beverages with their meals have an increased rise of triglycerides following the meal ... Increased triglycerides after a meal are known predictors of cardiovascular disease"
• Cortisol And Fatty Liver: Researchers Find Cause Of Severe Metabolic Disorders - Science Daily, 9/11/08 - "The researchers in Herzig's team specifically switched off the cortisol receptor in the livers of mice, thus blocking the hormone's effect. As a result, the triglyceride level in the livers of the experimental animals dropped considerably"
• Marijuana Users Have Increased apoC3, Triglycerides - Medscape, 5/19/08 - "Heavy, chronic use of marijuana causes increased levels of apolipoprotein C3 (apoC3), which in turn results in a major increase in triglyceride levels"
• Metformin May Delay Onset of Diabetes in At-Risk Subjects - Medscape, 3/24/08 - "Metformin treatment, compared with placebo or no treatment, reduced body mass index by 5.3%, fasting glucose by 4.5%, fasting insulin by 14.4%, and calculated insulin resistance by 22.6% ... Metformin treatment also reduced triglycerides and LDL cholesterol by 5.3% and 5.6%, respectively, and increased HDL cholesterol by 5.0% ... The incidence of new-onset diabetes was reduced by 40% (odds ratio, 0.6), with an absolute risk reduction of 6%, during a mean trial duration of 1.8 years" - I don't have diabetes yet still take 1,000 mg of metformin per day.  I still feel high blood sugar and advanced glycation end products are major causes of aging.  See metformin at OffshoreRx1.com.
• Low serum testosterone in men is inversely associated with non-fasting serum triglycerides: The Tromsø study - Nutr Metab Cardiovasc Dis. 2007 Jun 7 - "a linear increase in serum TG levels was found in men with total testosterone levels below the 50th percentile during the day (p for trend=0.004). In contrast, serum triglycerides did not change during the day in men with testosterone levels above the 50th percentile. In regression analyses, total testosterone and SHBG were inversely and independently associated with TG (p<0.001 and p<0.001 respectively), and positively and independently associated with HDL"
• The prevalence of newly diagnosed hyperlipidaemia in men with erectile dysfunction - BJU Int. 2007 Jun 6 - "This study shows the high prevalence of undiagnosed hypercholesterolaemia and hypertriglyceridaemia in men presenting with ED"
• Telmisartan improves lipid metabolism and adiponectin production but does not affect glycemic control in hypertensive patients with type 2 diabetes - Adv Ther. 2007 Jan-Feb;24(1):146-53 - "Triglyceride levels were significantly decreased, however, and adiponectin levels were significantly increased"
• Mixed Results for Cardiovascular Drug - WebMD, 11/14/05
• Big Waist + High Blood Fats = Heart Danger - WebMD, 4/18/05 - "heart deaths concentrate in women with just two factors -- high levels of triglycerides and a 34 2/3-inch waist or larger"
• Winning The Battle Of The Bulge: We're A Scrimmage Closer To Victory - Science Daily, 4/29/04 - "High triglycerides are blocking the leptin from getting into the brain. If leptin can't get into the brain, it can't tell you to stop eating ... If you lower triglycerides, you should theoretically help the body's own leptin to work better so people can get skinnier"
• Four Part Treatment Regimen Recommended for Severe Hypertriglyceridaemia - Doctor's Guide, 10/3/03
• Non-Fasting Triglyceride Levels May Be Useful in Coronary Heart Disease Risk Stratification - Doctor's Guide, 5/27/03
• Nonfasting Triglyceride Levels Predict Cardiovascular Risk - Doctor's Guide, 5/23/03
• Relation of Triglyceride Levels, Fasting and Nonfasting, to Fatal and Nonfatal Coronary Heart Disease - Archives of Internal Medicine, 5/12/03 - "nonfasting TG levels may be more useful than fasting ones for risk stratification"
• Unhealthy Trans Fats Not Labeled on Foods - WebMD, 2/10/03 - "[Trans fats] are there and they are not labeled ... Saturated fats are the only fats given special treatment on a product's label. Yet trans fats are just as bad. They may even be worse ... Trans fat increases 'bad' LDL cholesterol -- in some studies more than saturated fat ... It also has a tendency to reduce 'good' HDL cholesterol, which saturated fat doesn't do ... Trans fat also increases blood levels of two other bad actors. One is the kind of fat called triglycerides. The other is a particle called lipoprotein(a), which promotes clogged arteries ... Any amount of trans fat is bad"
• Ezetimibe Plus Simvastatin Safely Improves Lipid Profile - Doctor's Guide, 1/17/03 - "Ezetimibe and simvastatin given together reduced low-density lipoprotein cholesterol by 44 to 57%, reduced triglycerides by 20 to 28% and raised high-density lipoprotein cholesterol by 8 to 11%, depending on the simvastatin dose" - Ezetimibe is a cholesterol absorption inhibitor, simvastatin is a statin.
• Big gut, other factors can kill you - USA Today, 12/3/02 - "People with this syndrome have at least three of the following risk factors: high blood sugar; a waist circumference of greater than 40 inches for men or 35 inches for women; lower-than-average HDL cholesterol (the so-called good cholesterol); high triglycerides and high blood pressure ... men who had the syndrome at the study's start had a two to three times greater chance of dying of a heart attack or a stroke during the study than men who did not have this collection of risk factors ... People getting a checkup should ask their family doctor to look for metabolic syndrome"
• New Study Indicates Pioglitazone HCl/Metformin Combination Therapy Enhances Glycemic Control in Patients With Type 2 Diabetes - Doctor's Guide, 11/7/02 - "Diabetes patients taking the insulin sensitizer pioglitazone HCl in combination with metformin experienced significantly greater improvement in triglyceride levels than patients taking rosiglitazone maleate and metformin"
• High Triglycerides Common In Cystic Fibrosis Patients - Doctor's Guide, 6/11/02
• High Triglycerides, Higher Stroke Risk - Intelihealth, 12/19/01 - "Participants with high triglycerides had a 27 percent higher risk of ischemic strokes and transient ischemic attacks, or TIAs, than participants with normal triglyceride levels. People with high levels of high-density lipoprotein (HDL), so-called good cholesterol, were less likely to have strokes than those with lower HDL ... the results provide another reason for people with coronary heart disease to control triglycerides and not just cholesterol ... This also confirms that the high-density cholesterol, HDL, is very important"
• Triglycerides May Be Stroke Indicator - Intelihealth, 12/11/01 - "heart patients who have high levels of these fatty particles in their blood run a higher risk of a stroke, even if their cholesterol is low ... this study is the first to identify triglycerides as an independent risk factor for stroke ... The lesson from our study is, in addition to managing well the bad cholesterol, one should not ignore the triglycerides ... Those with high levels of triglycerides, or over 200 milligrams per deciliter, had a nearly 30 percent higher risk of stroke. The heart association says the normal level for triglycerides is less than 150"
• Atorvastatin May Lower LDL And Triglycerides In Type 2 Diabetics - Doctor's Guide, 6/24/01
• Low-Fat, High-Carbohydrate Diets Not Necessarily Cause Hypertriglyceridemia - Doctor's Guide, 5/31/01
• Niaspan (Niacin Extended Release Tablets) Safe And Effective For Diabetics - Doctor's Guide, 11/14/00 - "Results from the trial indicated that Niaspan therapy increased HDL up to 24 percent and decreased triglycerides as much as 30 percent"
• Do Triglyceride Tests Really Help Predict Heart Disease? - WebMD, 7/10/00
• Study: Heart risks rise with high triglycerides even if cholesterol normal - CNN, 6/20/00
• High Blood Triglycerides Linked To High Risk Of Heart Disease Mortality - Doctor's Guide, 6/19/00
• FDA Approves New Lescol Indication To Reduce Triglycerides And Apo B - Doctor's Guide, 3/9/99
• Very Low Fat Diets May Not Provide Additional Benefit - Doctor's Guide, 8/31/98 - "Very low fat diets, at least in the short term, tend to increase triglycerides and decrease good cholesterol, or HDL, levels without yielding additional decreases in LDL levels"
• TriCor, Micronized Fenofibrate, Now Available In U.S. For High Triglycerides - Doctor's Guide, 6/2/98
• Triglyceride Levels May Be Independent Risk Factor For Heart Attack - Doctor's Guide, 3/24/98
• FDA Approves Zocor To Lower Both Cholesterol and Triglycerides - Doctor's Guide, 11/6/97
• Triglyceride Blood Levels Predict Heart Attack - Doctor's Guide, 10/30/97