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Recent Longevity News for the seven days ending 12/17/08. You should consult your doctor if you are taking any medications. Low Dose Of Caffeine When Pregnant May Damage Heart Of Offspring For A Lifetime - Science Daily, 12/16/08 - "the equivalent of one dose of caffeine (just two cups of coffee) ingested during pregnancy may be enough to affect fetal heart development and then reduce heart function over the entire lifespan of the child" FDA OKs New Cholesterol Drug Trilipix - WebMD, 12/15/08 - "The FDA has approved a new drug called Triliplix for use along with diet to lower LDL ("bad") cholesterol, lower triglycerides, and raise HDL ("good") cholesterol" High Blood Pressure May Make It Difficult For The Elderly To Think Clearly - Science Daily, 12/15/08 - "subjects whose average systolic blood pressure was 130 or higher saw a significant decrease in cognitive function when their blood pressure spiked ... study subjects whose average blood pressure was low or normal saw no change in their cognitive functioning – even when their blood pressure shot up"
Nearly
Three-quarters Of Youths With Diabetes Insufficient In Vitamin D - Science
Daily, 12/15/08 - "Three-quarters of youths with type 1
diabetes were found to have insufficient levels
of vitamin D, according to a study by
researchers at the Joslin Diabetes Center – findings that suggest children with
the disease may need vitamin D supplementation to prevent bone fragility later
in life" - See
vitamin D at Amazon.com
Broccoli
Compound Targets Key Enzyme In Late-stage Cancer - Science Daily, 12/14/08 -
"The new findings are the first to explain how
indole-3-carbinol (I3C) stops cell growth, and thus
provides the basis for designing improved versions of the chemical that would be
more effective as a drug and could work against a broader range of breast as
well as prostate tumors ... I3C inhibits the enzyme elastase, which at high
levels in breast cancer cells heralds a poor prognosis: decreased response to
chemotherapy, reduced response to endocrine treatment and reduced survival
rates" - See
indole 3 carbinol at Amazon.com Berry extracts may ease age-related mental decline: Study - Nutra USA, 12/12/08 - "The results indicated that in aging rats, pterostilbene was effective in reversing the decline in cognitive function that occurs with naturally with age, and that precedes diseases such as Alzheimer's" - [Abstract] Healthier Holiday Cookie Recipes - WebD, 12/12/08 - "4 Healthier Holiday Cookie Recipes"
Pine bark extract may help joints and hearts: Study - Nutra USA, 12/11/08 -
"The decrease of systemic
inflammatory markers, particularly
CRP, suggests
Pycnogenol properties may be potent enough to
arrest the spread of inflammation from
osteoarthritic joints to the whole organisms ... subjects received either
two daily doses of 50 mg Pycnogenol or placebo for three months ... people
receiving the pine bark extract experienced significant reductions in CRP levels
from an average of 3.9 mg/L at the start of the study to 1.1 mg/L after three
months. This is equivalent to a 71 per cent reduction ... Moreover, a reduction
in the blood levels of reactive oxygen species (ROS) of 30 per cent was
recorded" - See
Pycnogenol at Amazon.com Are clinical trials short-changing us? - Nutra USA, 12/11/08 - "The same questions jump to my mind all the time: Where’s the control group? Are the people in the placebo group actually taking supplements on the side? How long is the latency period for the disease in question? ... Let’s address these one by one: ..." - Related article:
Low-carb Diets Can Affect Dieters' Cognition Skills - Science Daily, 12/11/08 - "A new study from the psychology department at Tufts University shows that when dieters eliminate carbohydrates from their meals, they performed more poorly on memory-based tasks than when they reduce calories, but maintain carbohydrates. When carbohydrates were reintroduced, cognition skills returned to normal"
Lack Of
Vitamin D Causes Weight Gain And Stunts Growth In Girls - Science Daily,
12/11/08 - The high prevalence of
vitamin D insufficiency in young people living
in a sun-rich area was surprising ... "We found young women with vitamin D
insufficiency were significantly heavier, with a
higher body mass index and increased
abdominal fat, than young women with normal levels" - See
vitamin D at Amazon.com
Vitamin D Deficiency Increases Risk of Cardiovascular Disease - Doctor's
Guide, 12/10/08 - "a review article published in the
December 9 issue of the Journal of the American College of Cardiology ...
patients with vitamin D levels below 15 ng/mL
were twice as likely to experience a heart attack,
stroke, or other CV event within
the next 5 years compared with those with higher levels" - See
vitamin D at Amazon.com Testosterone Gel Addition Benefits Men With Erectile Dysfunction Who Do Not Respond to PDE5s Alone if Testosterone Levels Are Low - Doctor's Guide, 12/10/08 - "Addition of testosterone gel to improve efficacy of the phosphodiesterase-5 (PDE5) inhibitor tadalafil in men with erectile dysfunction (ED) shows significant improvements for those with a serum testosterone level <=3 ng/mL at baseline" Popular Class Of Diabetes Drugs Doubles Risk Of Fractures In Women - Science Daily, 12/10/08 - "We knew going into this study that there was an association between thiazolidinediones and fracture risk ... these agents double the risk of fractures in women with type 2 diabetes" Abstracts from this week's Doctor's Guide Nutrition/Dietetics plus abstracts from my RSS feeds (Click here for the journals, the PubMed ones at the top):
Vitamin d,
respiratory infections, and asthma - Curr Allergy Asthma Rep. 2009
Jan;9(1):81-7 - "Emerging evidence indicates that
vitamin D-mediated innate immunity,
particularly through enhanced expression of the human cathelicidin antimicrobial
peptide (hCAP-18), is important in host defenses against respiratory tract
pathogens. Observational studies suggest that vitamin D deficiency increases
risk of respiratory infections.
This increased risk may contribute to incident wheezing illness in children and
adults and cause asthma exacerbations. Although
unproven, the increased risk of specific respiratory infections in susceptible
hosts may contribute to some cases of incident asthma. Vitamin D also modulates
regulatory T-cell function and interleukin-10 production, which may increase the
therapeutic response to glucocorticoids in steroid-resistant asthma" -
See
vitamin D at Amazon.com Flaxseed Supplementation (Not Dietary Fat Restrict...[Cancer Epidemiol Biomarkers Prev. 2008] - PubMed Result - Cancer Epidemiol Biomarkers Prev. 2008 Dec;17(12):3577-3587 - "Men were on protocol an average of 30 days. Proliferation rates were significantly lower (P < 0.002) among men assigned to the flaxseed arms. Median Ki-67-positive cells/total nuclei ratios (x100) were 1.66 (flaxseed-supplemented diet) and 1.50 (flaxseed-supplemented, low-fat diet) versus 3.23 (control) and 2.56 (low-fat diet) ... Findings suggest that flaxseed is safe and associated with biological alterations that may be protective for prostate cancer" Straight talk about high-fructose corn syrup: what it is and what it ain't - Am J Clin Nutr. 2008 Dec;88(6):1716S-1721S - "Although examples of pure fructose causing metabolic upset at high concentrations abound, especially when fed as the sole carbohydrate source, there is no evidence that the common fructose-glucose sweeteners do the same. Thus, studies using extreme carbohydrate diets may be useful for probing biochemical pathways, but they have no relevance to the human diet or to current consumption. I conclude that the HFCS-obesity hypothesis is supported neither in the United States nor worldwide"
Fish
consumption and risk of major chronic disease in men - Am J Clin Nutr. 2008
Dec;88(6):1618-1625 - "Compared with
fish consumption of <1 serving/mo,
consumption of 1 serving/wk and of 2-4 servings/wk was associated with a lower
risk of total cardiovascular disease
of approximately 15%"
- See
Mega Twin EPA at Amazon.com Differences in vitamin D status as a possible contributor to the racial disparity in peripheral arterial disease - Am J Clin Nutr. 2008 Dec;88(6):1469-1477 - "Differences in vitamin D status as a possible contributor to the racial disparity in peripheral arterial disease" Erectile Dysfunction in Men With Congenital Heart Disease - Am J Cardiol. 2008 Dec 15;102(12):1728-1730 - "beta blockers ... Men on BB were 3.13 times more likely to report ED" Neat Tech Stuff (PDF converters):
Supplement Focus (cranberry extract): Cranberry News & Research:
Cranberry Abstracts:
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