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Home > Health Conditions > Urinary Track Infections

Urinary Tract Infections

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  • Zinc could help as non-antibiotic treatment for UTIs - Science Daily, 3/8/19 -"UTIs are one of the most common bacterial infections worldwide with about 150 million cases each year, and can lead to serious conditions such as kidney infection and sepsis ... We confirmed by direct visualisation that cells in our immune system known as macrophages deploy zinc to clear bacterial infections ... Treatment strategies that don't use antibiotics have the advantage of bacteria not developing resistance; if we can reprogram our immune cells to make them stronger, or change the way they respond to bacteria, we would be better equipped to fight superbugs"
  • Drinking Enough Water Could Be Key to Avoiding UTIs - WebMD, 10/1/18 - "The new trial included 140 younger, premenopausal women in Europe who had all experienced high numbers of recurrent UTIs. Their total daily fluid intake at the start of the study totaled less than six 8-ounce glasses per day ... During the year-long trial, half of the women drank just over six cups more each day of water, in addition to their regular daily fluid intake. Intake remained the same for the other half of women ... The reduction in UTI frequency for those who drank the additional water was significant. While the average number of UTIs during the study period was 3.2 for women who did not increase their water intake, it fell to 1.7 for those women whose intake rose"
  • Urox containing concentrated extracts of Crataeva nurvala stem bark, Equisetum arvense stem and Lindera aggregata root, in the treatment of symptoms of overactive bladder and urinary incontinence: a phase 2, randomised, double-blind placebo controlled trial - BMC Complement Altern Med. 2018 Jan 31 - "Storage lower urinary tract symptoms (LUTS) including overactive bladder (OAB) and urinary incontinence (UI) affect millions of people worldwide, significantly impacting quality of life. Plant based medicines have been documented both empirically and in emerging scientific research to have varying benefits in reducing bladder symptoms. We assessed the efficacy of Urox®, a proprietary combination of phytomedicine extracts including, Cratevox™ (Crataeva nurvala) stem bark, Equisetem arvense stem and Lindera aggregata root, in reducing symptoms of OAB and UI ... The outcome of this study demonstrated both statistical significance and clinical relevance in reducing symptoms of OAB, urinary frequency and/or urgency and incontinence. The demonstrated viability of the herbal combination to serve as an effective treatment, with minimal side-effects, warrants further longer term research and consideration by clinicians" - See Urox® at Amazon.com.
  • Probiotics in Preventing Recurrent UTIs in Women - Medscape, 5/4/15 - "Lactobacillus probiotics, taken either orally or vaginally, are likely effective in reducing recurrent urinary tract infections in women. Although more research is needed, probiotics should be considered a useful and safe alternative to antibiotics. By minimizing exposure to antibiotics, nursing professionals have the potential to decrease antibiotic resistance in communities, de crease side effects in women, and in turn, improve their quality of life" - See probiotic products at Amazon.com.
  • Lactobacillus Probiotics May Prevent Recurrent UTIs - Medscape, 9/20/13 - "randomised double-blind non-inferiority trial comparing lactobacilli to trimethoprim–sulfamethoxazole (TMP-SMX) in 252 postmenopausal women with a history of at least three self-reported symptomatic UTIs within the preceding year ... After 12 months of prophylaxis, the mean number of clinical UTI recurrence (CR) was 2.9 in the TMP-SMX group and 3.3 in the lactobacilli group (p=0.42). The mean number of microbiological recurrence (MR) was significantly less in TMP-SMX group at 1.2 compared with 1.8 in the lactobacilli group (p=0.02). For both CR and MR, a higher proportion of women in the lactobacilli group experienced at least one UTI recurrence and the median time to first recurrence was significantly shorter in the lactobacilli group. In women with complicated UTIs, the mean number of CRs was 4.4 in the TMP-SMX group compared with 3.4 in the lactobacilli group (p<0.001), suggesting a favourable effect of lactobacilli in this subgroup. With regard to adverse events, there were no significant differences between groups, although the lactobacilli group had a non-significantly higher number of treatment-related withdrawals with gastrointestinal side effects being the most common" - See Garden of Life, Primal Defense at Amazon.com.
  • How Cranberries Impact Infection-Causing Bacteria - Science Daily, 7/15/13 - "cranberry powder can inhibit the ability of Proteus mirabilis, a bacterium frequently implicated in complicated UTIs, to swarm on agar plates and swim within the agar. The experiments also show that increasing concentrations of cranberry powder reduce the bacteria's production of urease, an enzyme that contributes to the virulence of infections" - See cranberry extract at Amazon.com.
  • Lactobacilli versus antibiotics to prevent urinary tract infections: a randomized, double-blind, noninferiority trial in postmenopausal women - Ned Tijdschr Geneeskd. 2013;157(7):A5674 - "In postmenopausal women with recurrent UTIs, L. rhamnosus GR-1 and L. reuteri RC-14 do not meet the noninferiority criteria in the prevention of UTIs when compared with CTX. However, unlike CTX, lactobacilli do not increase antibiotic resistance" - See lactobacillus products at iHerb.
  • Lactobacilli vs Antibiotics to Prevent Urinary Tract Infections: A Randomized, Double-blind, Noninferiority Trial in Postmenopausal Women - Arch Intern Med. 2012 May 14;172(9):704-12 - "Growing antibiotic resistance warrants studying nonantibiotic prophylaxis for recurrent urinary tract infections (UTIs). Use of lactobacilli appears to be promising ... Between January 2005 and August 2007, we randomized 252 postmenopausal women with recurrent UTIs taking part in a double-blind noninferiority trial to receive 12 months of prophylaxis with trimethoprim-sulfamethoxazole, 480 mg, once daily or oral capsules containing 109 colony-forming units of Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 twice daily ...The mean number of symptomatic UTIs in the year preceding randomization was 7.0 in the trimethoprim-sulfamethoxazole group and 6.8 in the lactobacilli group. In the intention-to-treat analysis, after 12 months of prophylaxis, these numbers were 2.9 and 3.3, respectively. The between-treatment difference of 0.4 UTIs per year (95% CI, -0.4 to 1.5) was outside our noninferiority margin. At least 1 symptomatic UTI occurred in 69.3% and 79.1% of the trimethoprim-sulfamethoxazole and lactobacilli participants, respectively; median times to the first UTI were 6 and 3 months, respectively. After 1 month of trimethoprim-sulfamethoxazole prophylaxis, resistance to trimethoprim-sulfamethoxazole, trimethoprim, and amoxicillin had increased from approximately 20% to 40% to approximately 80% to 95% in E coli from the feces and urine of asymptomatic women and among E coli causing a UTI. During the 3 months after trimethoprim-sulfamethoxazole discontinuation, resistance levels gradually decreased. Resistance did not increase during lactobacilli prophylaxis. CONCLUSIONS In postmenopausal women with recurrent UTIs, L rhamnosus GR-1 and L reuteri RC-14 do not meet the noninferiority criteria in the prevention of UTIs when compared with trimethoprim-sulfamethoxazole. However, unlike trimethoprim-sulfamethoxazole, lactobacilli do not increase antibiotic resistance" - See lactobacillus products at iHerb.
  • Cranberry Products May Prevent Urinary Tract Infections - Medscape, 7/9/12 - "Several new studies have been published since the last meta-analysis on this issue ... Dr. Wang and colleagues analyzed 10 trials with a total of 1494 participants ... cranberry-containing products appeared to effectively prevent UTIs (RR, 0.62; 95% CI, 0.49 - 0.80) (I2 = 43%)" - [Abstract] - See cranberry extract at Amazon.com.
  • Vitamin D and Lower Urinary Tract Symptoms Among US Men: Results From the 2005-2006 National Health and Nutrition Examination Survey - Urology. 2011 Oct 17 - "vitamin D deficiency was associated with the presence of moderate-severe UI (POR 1.8, 95% CI 1.1, 3.0) and at least 1 LUTS (POR 1.4, 95% CI 1.0, 2.0)" - See vitamin D at Amazon.com.
  • Probiotic may reduce rate of recurrent urinary tract infections in women, study suggests - Science Daily, 4/15/11 - "Of the 100 women who participated in the study, 50 received LACTIN-V, and 50 received the placebo. Seven of the women who received LACTIN-V had at least one urinary tract infection, compared to 13 in the placebo group" - See probiotics at Amazon.com.
  • Whole cranberry powder shows activity against recurrent UTIs - Nutra USA, 4/5/11 - "The volunteers were randomly assigned to receive no intervention, or a low (500 mg) or high dose (1,000 mg) daily dose of the PACran whole cranberry powder for 90 days ... At the end of the study, the control group did not show any changes in concentrations of E. coli, while a significant reduction in the cranberry groups were observed. Specifically, the researchers report a reductions of E. coli in urine culture analysis of between 25 and 45 percent after 10 days of cranberry consumption, and this was maintained over 90 days" - See cranberry extract at Amazon.com.
  • How Cranberry Products Prevent Urinary Tract Infections - Science Daily, 5/9/08 - "Chemicals present in cranberries—and not the acidity of cranberry juice, as previously thought—prevent infection-causing bacteria from attaching to the cells that line the urinary tract ... Chemicals found in cranberry products called proanthocyanidins (PACs) prevent E. coli, which is the cause of about 85% of UTIs and 90% of cases of acute pyelonephritis, from adhering to these urinary tract epithelial cells by affecting the surface properties of the bacteria" - See cranberry extract at Amazon.com.
  • Cranberry near match for antibiotic UTI potential - study - Nutra USA, 12/23/08
  • Cranberries Might Help Prevent Urinary Infections In Women - Science Daily, 1/22/07 - "cranberry products significantly reduced UTIs over 12 months compared to the placebo/control groups. The cranberry treatment was more effective for women who suffered from recurrent UTIs" - See cranberry extract at Amazon.com.
  • Cranberries Help Combat Urinary Tract Infections In Women, Researcher Finds - Science Daily, 1/14/08
  • The Chemistry Behind UTIs - mercola.com, 3/30/05
  • More Cranberries, Fewer Urine Infections - WebMD, 9/30/04
  • What can women do about recurrent bladder infections? - Natural Foods Merchandiser, 10/03
  • Diet May Protect Women against Urinary Tract Infections - New Hope Natural Media, 5/29/03
  • Dietary factors protecting women from urinary tract infection - Am. J. of Clin. Nutri., 3/1/03 - "Frequent consumption of fresh juices, especially berry juices, and fermented milk products containing probiotic bacteria was associated with a decreased risk of recurrence of UTI"
  • Diet Drops Bladder-Infection Risk - WebMD, 2/27/03
  • Cranberry Juice May Prevent Urinary Tract Infections - New Hope Natural Media, 7/18/02 - "Women who consume cranberry juice (Vaccinium macrocarpon) on a daily basis may help prevent the urinary tract infections (UTIs), according to a new study in the Journal of the American Medical Association ... Another herbal treatment that may be helpful for UTIs is uva ursi"
  • The Cranberry Cure, A Glass a Day Could Keep Urinary Infections Away - WebMD, 6/29/01 - "After six months, only eight women taking cranberry juice had experienced a UTI, compared with 19 of those taking Lactobacillus, and 18 not taking anything"
  • Cranberry Juice Helps Urinary Tract - Intelihealth, 6/29/01
  • The Cranberry Cure, A Glass a Day Could Keep Urinary Infections Away - WebMD, 9/14/00
  • Does drinking cranberry juice stop bladder infections? - Nutrition Science News, 5/99

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