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Home > Health
Conditions > Urinary Track Infections
Urinary Tract Infections
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Alternative News:
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Zinc
could help as non-antibiotic treatment for UTIs - Science Daily, 3/8/19 -"UTIs
are one of the most common bacterial infections worldwide with about 150 million
cases each year, and can lead to serious conditions such as kidney infection and
sepsis ... We confirmed by direct visualisation that cells in our immune system
known as macrophages deploy zinc to clear bacterial infections ... Treatment
strategies that don't use antibiotics have the advantage of bacteria not
developing resistance; if we can reprogram our immune cells to make them
stronger, or change the way they respond to bacteria, we would be better
equipped to fight superbugs"
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Drinking Enough Water Could Be Key to Avoiding UTIs - WebMD, 10/1/18 -
"The new trial included 140 younger, premenopausal women
in Europe who had all experienced high numbers of recurrent UTIs. Their total
daily fluid intake at the start of the study totaled less than six 8-ounce
glasses per day ... During the year-long trial, half of the women drank just
over six cups more each day of water, in addition to their regular daily fluid
intake. Intake remained the same for the other half of women ... The reduction
in UTI frequency for those who drank the additional water was significant. While
the average number of UTIs during the study period was 3.2 for women who did not
increase their water intake, it fell to 1.7 for those women whose intake rose"
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Urox containing
concentrated extracts of Crataeva nurvala stem bark, Equisetum arvense stem and
Lindera aggregata root, in the treatment of symptoms of overactive bladder and
urinary incontinence: a phase 2, randomised, double-blind placebo controlled
trial - BMC Complement Altern Med. 2018 Jan 31 - "Storage lower urinary
tract symptoms (LUTS) including overactive bladder (OAB) and urinary
incontinence (UI) affect millions of people worldwide, significantly impacting
quality of life. Plant based medicines have been documented both empirically and
in emerging scientific research to have varying benefits in reducing bladder
symptoms. We assessed the efficacy of Urox®, a proprietary combination of
phytomedicine extracts including, Cratevox™ (Crataeva nurvala) stem bark,
Equisetem arvense stem and Lindera aggregata root, in reducing symptoms of OAB
and UI ... The outcome of this study demonstrated both statistical significance
and clinical relevance in reducing symptoms of OAB, urinary frequency and/or
urgency and incontinence. The demonstrated viability of the herbal combination
to serve as an effective treatment, with minimal side-effects, warrants further
longer term research and consideration by clinicians" - See
Urox® at Amazon.com.
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Probiotics in Preventing
Recurrent UTIs in Women - Medscape, 5/4/15 -
"Lactobacillus probiotics, taken either orally or vaginally, are likely
effective in reducing recurrent urinary tract infections in women. Although more
research is needed, probiotics should be considered a useful and safe
alternative to antibiotics. By minimizing exposure to antibiotics, nursing
professionals have the potential to decrease antibiotic resistance in
communities, de crease side effects in women, and in turn, improve their quality
of life" - See
probiotic products at Amazon.com.
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Lactobacillus Probiotics
May Prevent Recurrent UTIs - Medscape, 9/20/13 -
"randomised double-blind non-inferiority trial comparing lactobacilli to
trimethoprim–sulfamethoxazole (TMP-SMX) in 252 postmenopausal women with a
history of at least three self-reported symptomatic UTIs within the preceding
year ... After 12 months of prophylaxis, the mean number of clinical UTI
recurrence (CR) was 2.9 in the TMP-SMX group and 3.3 in the lactobacilli group
(p=0.42). The mean number of microbiological recurrence (MR) was significantly
less in TMP-SMX group at 1.2 compared with 1.8 in the lactobacilli group
(p=0.02). For both CR and MR, a higher proportion of women in the lactobacilli
group experienced at least one UTI recurrence and the median time to first
recurrence was significantly shorter in the lactobacilli group. In women with
complicated UTIs, the mean number of CRs was 4.4 in the TMP-SMX group compared
with 3.4 in the lactobacilli group (p<0.001), suggesting a favourable effect of
lactobacilli in this subgroup. With regard to adverse events, there were no
significant differences between groups, although the lactobacilli group had a
non-significantly higher number of treatment-related withdrawals with
gastrointestinal side effects being the most common" - See
Garden of Life, Primal Defense at Amazon.com.
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How
Cranberries Impact Infection-Causing Bacteria - Science Daily, 7/15/13 -
"cranberry powder can inhibit the ability of Proteus
mirabilis, a bacterium frequently implicated in complicated UTIs, to swarm on
agar plates and swim within the agar. The experiments also show that increasing
concentrations of cranberry powder reduce the bacteria's production of urease,
an enzyme that contributes to the virulence of infections" - See
cranberry extract at Amazon.com.
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Lactobacilli versus
antibiotics to prevent urinary tract infections: a randomized, double-blind,
noninferiority trial in postmenopausal women - Ned Tijdschr Geneeskd.
2013;157(7):A5674 - "In postmenopausal women with
recurrent UTIs, L. rhamnosus GR-1 and L. reuteri RC-14 do not meet the
noninferiority criteria in the prevention of UTIs when compared with CTX.
However, unlike CTX, lactobacilli do not increase antibiotic resistance"
- See
lactobacillus products at iHerb.
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Lactobacilli
vs Antibiotics to Prevent Urinary Tract Infections: A Randomized, Double-blind,
Noninferiority Trial in Postmenopausal Women - Arch Intern Med. 2012 May
14;172(9):704-12 - "Growing antibiotic resistance
warrants studying nonantibiotic prophylaxis for recurrent urinary tract
infections (UTIs). Use of lactobacilli appears to be promising ... Between
January 2005 and August 2007, we randomized 252 postmenopausal women with
recurrent UTIs taking part in a double-blind noninferiority trial to receive 12
months of prophylaxis with trimethoprim-sulfamethoxazole, 480 mg, once daily or
oral capsules containing 109 colony-forming units of Lactobacillus rhamnosus
GR-1 and Lactobacillus reuteri RC-14 twice daily ...The mean number of
symptomatic UTIs in the year preceding randomization was 7.0 in the
trimethoprim-sulfamethoxazole group and 6.8 in the lactobacilli group. In the
intention-to-treat analysis, after 12 months of prophylaxis, these numbers were
2.9 and 3.3, respectively. The between-treatment difference of 0.4 UTIs per year
(95% CI, -0.4 to 1.5) was outside our noninferiority margin. At least 1
symptomatic UTI occurred in 69.3% and 79.1% of the trimethoprim-sulfamethoxazole
and lactobacilli participants, respectively; median times to the first UTI were
6 and 3 months, respectively. After 1 month of trimethoprim-sulfamethoxazole
prophylaxis, resistance to trimethoprim-sulfamethoxazole, trimethoprim, and
amoxicillin had increased from approximately 20% to 40% to approximately 80% to
95% in E coli from the feces and urine of asymptomatic women and among E coli
causing a UTI. During the 3 months after trimethoprim-sulfamethoxazole
discontinuation, resistance levels gradually decreased. Resistance did not
increase during lactobacilli prophylaxis. CONCLUSIONS In postmenopausal women
with recurrent UTIs, L rhamnosus GR-1 and L reuteri RC-14 do not meet the
noninferiority criteria in the prevention of UTIs when compared with
trimethoprim-sulfamethoxazole. However, unlike trimethoprim-sulfamethoxazole,
lactobacilli do not increase antibiotic resistance" - See
lactobacillus products at iHerb.
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Cranberry Products
May Prevent Urinary Tract Infections - Medscape, 7/9/12 -
"Several new studies have been published since the last
meta-analysis on this issue ... Dr. Wang and colleagues analyzed 10 trials with
a total of 1494 participants ... cranberry-containing products appeared to
effectively prevent UTIs (RR, 0.62; 95% CI, 0.49 - 0.80) (I2 = 43%)"
- [Abstract]
- See
cranberry extract at Amazon.com.
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Vitamin D
and Lower Urinary Tract Symptoms Among US Men: Results From the 2005-2006
National Health and Nutrition Examination Survey - Urology. 2011 Oct 17 -
"vitamin D deficiency was associated with the presence
of moderate-severe UI (POR 1.8, 95% CI 1.1, 3.0) and at least 1 LUTS (POR 1.4,
95% CI 1.0, 2.0)" - See
vitamin D at Amazon.com.
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Probiotic may reduce rate of recurrent urinary tract infections in women, study
suggests - Science Daily, 4/15/11 - "Of the 100
women who participated in the study, 50 received LACTIN-V, and 50 received the
placebo. Seven of the women who received LACTIN-V had at least one urinary tract
infection, compared to 13 in the placebo group" - See
probiotics at Amazon.com.
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Whole cranberry powder shows activity against recurrent UTIs - Nutra USA,
4/5/11 - "The volunteers were randomly assigned to
receive no intervention, or a low (500 mg) or high dose (1,000 mg) daily dose of
the PACran whole cranberry powder for 90 days ... At the end of the study, the
control group did not show any changes in concentrations of E. coli, while a
significant reduction in the cranberry groups were observed. Specifically, the
researchers report a reductions of E. coli in urine culture analysis of between
25 and 45 percent after 10 days of cranberry consumption, and this was
maintained over 90 days"
- See
cranberry extract at Amazon.com.
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How
Cranberry Products Prevent Urinary Tract Infections - Science Daily,
5/9/08 - "Chemicals present in cranberries—and not
the acidity of cranberry juice, as previously thought—prevent
infection-causing bacteria from attaching to the cells that line the urinary
tract ... Chemicals found in cranberry products called proanthocyanidins
(PACs) prevent E. coli, which is the cause of about 85% of UTIs and 90% of
cases of acute pyelonephritis, from adhering to these urinary tract
epithelial cells by affecting the surface properties of the bacteria"
- See
cranberry extract at Amazon.com.
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Cranberry near match for antibiotic UTI potential - study - Nutra USA,
12/23/08
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Cranberries Might Help Prevent Urinary Infections In Women - Science
Daily, 1/22/07 - "cranberry products significantly
reduced UTIs over 12 months compared to the placebo/control groups. The
cranberry treatment was more effective for women who suffered from recurrent
UTIs" - See
cranberry extract at Amazon.com.
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Cranberries Help Combat Urinary Tract Infections In Women, Researcher Finds
- Science Daily, 1/14/08
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The Chemistry Behind UTIs - mercola.com, 3/30/05
- More
Cranberries, Fewer Urine Infections - WebMD, 9/30/04
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What can women do about recurrent bladder infections? - Natural Foods
Merchandiser, 10/03
- Diet May Protect Women
against Urinary Tract Infections - New Hope Natural Media, 5/29/03
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Dietary factors protecting women from urinary tract infection - Am. J.
of Clin. Nutri., 3/1/03 -
"Frequent consumption of fresh juices, especially
berry juices, and fermented milk products containing
probiotic bacteria was associated with a decreased risk of recurrence of
UTI"
- Diet Drops
Bladder-Infection Risk - WebMD, 2/27/03
- Cranberry Juice May
Prevent Urinary Tract Infections - New Hope Natural Media, 7/18/02 -
"Women who consume
cranberry juice (Vaccinium macrocarpon) on a daily basis may help
prevent the urinary tract infections (UTIs), according to a new study in the
Journal of the American Medical Association ... Another herbal treatment
that may be helpful for UTIs is
uva ursi"
- The Cranberry
Cure, A Glass a Day Could Keep Urinary Infections Away - WebMD, 6/29/01
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"After six months, only eight women taking cranberry
juice had experienced a UTI, compared with 19 of those taking Lactobacillus,
and 18 not taking anything"
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Cranberry Juice Helps Urinary Tract - Intelihealth, 6/29/01
- The Cranberry
Cure, A Glass a Day Could Keep Urinary Infections Away - WebMD, 9/14/00
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Does drinking cranberry juice stop bladder infections? - Nutrition
Science News, 5/99
Other News:
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The
Influence of Urinary pH on Antibiotic Efficacy Against Bacterial
Uropathogens - Urology. 2014 Sep;84(3):731.e1-7 -
"Because human urine can substantially vary from
acidic (pH 4.5) to alkaline (pH 8) conditions and can be easily clinically
manipulated, it would be a great advantage to better understand the role of
pH in antibiotic treatment of urinary tract infection ... The
fluoroquinolones, co-trimoxazole, aminoglycosides, and macrolides all
functioned optimally at alkaline pH, whereas the tetracyclines,
nitrofurantoin, and many of the β-lactams tested exhibited their highest
activity under more acidic conditions. Sulfamethoxazole, oxacillin,
amoxicillin and clavulanic acid, vancomycin, imipenem, and clindamycin were
largely unaffected by pH"
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New
study on UTIs suggests flagellin is key in stimulating body's natural
defenses - Science Daily, 3/17/13 - "There is
rapidly growing resistance exhibited by organisms, especially E. coli, to
conventional antimicrobials which makes infections potentially more and more
difficult to treat ... This is confounded by the fact that there have been
no new classes of antibiotics to treat Gram-negative bacilli like E. coli
for more than 40 years. It is amazing that the fluoroquinolones were the
last new class of antibiotics to treat Gram-negative bacilli! Our ultimate
aim is to develop agents that enhance the immune response and help the body
defend itself better as an alternative to conventional antibiotics which
work against the pathogen alone"
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Common medications can contribute to lower urinary tract symptoms in men,
study finds - Science Daily, 10/11/11
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Retail meat linked to urinary tract infections: Strong new evidence -
Science Daily, 1/20/10 - "Chicken sold in
supermarkets, restaurants and other outlets may place young women at risk of
urinary tract infections (UTI) ... E. coli (Escherichia coli) bacteria
originating from these food sources can cause common urinary tract
infections"
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Why
Urinary Tract Infections Commonly Recur In Women - Science Daily, 1/3/08
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Bacteria That Cause Urinary Tract Infections Invade Bladder Cells -
Science Daily, 12/17/07
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FDA Approves New Drug to Treat Complicated Urinary Tract and Intra-Abdominal
Infections - Doctor's Guide, 10/18/07
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Oral
Antibiotics Effective To Treat Severe Urinary Tract Infections - Science
Daily, 10/16/07
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Depomed Receives FDA Approval of Proquin XR for Uncomplicated Urinary Tract
Infections - Doctor's Guide, 5/20/05
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Urinary-tract Infection Common After Pre-term Delivery - Doctor's Guide,
10/18/04
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Cipro XR (Ciprofloxacin) Demonstrates Rapid Symptom Improvement, Early
Return to Activities in Women With Uncomplicated Urinary Tract Infections
- Doctor's Guide, 10/18/04
- Medical Treatments
Effective for Urge, Stress, Mixed Urinary Incontinence - Medscape,
5/4/04
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Pivmecillinam Safe for Treating Pregnant Women with Urinary-Tract Infections
- Doctor's Guide, 5/4/04
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Extended-Release Ciprocloxacin In Management of Uncomplicated Urinary Tract
Infections - Doctor's Guide, 4/6/04
- Urinary tract infections going
untreated - MSNBC, 3/16/04
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Short Course of Antibiotics For Urinary Tract Infection In Elderly Women
Appears Safe, Effective - Doctor's Guide, 3/4/04
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Prior Fluoroquinolone Use Linked to Ciprofloxacin-Resistant Urinary-Tract
Infections - Doctor's Guide, 9/17/03
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Bladder Infections Can Be Managed by Telephone Communication with Patients
- Doctor's Guide, 9/17/03
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Macrobid (Nitrofurantoin Monohydrate/Macrocrystals) May Be Effective in
Treatment of Urinary Tract Infections After Surgery - Doctor's Guide,
9/12/03
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FDA Approves Once-Daily Cipro XR (Ciprofloxacin) for Treatment of
Complicated Urinary Tract Infections - Doctor's Guide, 8/29/03
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Bacteria Can Gang Up On You - CBS News, 7/4/03
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Oral Antibiotic Prophylaxis Reduces Post-Cystoscopy Infection - Doctor's
Guide, 4/28/03
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Ciprofloxacin XR Rivals Conventional Regimen for Some Urinary Tract
Infections and Acute Pyelonephritis - Doctor's Guide, 4/28/03
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Prior Antimicrobial Exposure Risk Factor For
Trimethoprim-Sulfamethoxazole-Resistant Urinary Tract Infections -
Doctor's Guide, 4/10/03
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FDA Approves Once-Daily Cipro (Ciprofloxacin) XR For Uncomplicated Urinary
Tract Infections - Doctor's Guide, 12/16/02
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Once Daily Extended Release Ciprofloxacin As Effective As Regular Dosing In
Urinary Tract Infections - Doctor's Guide, 10/28/02
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Check for Interstitial Cystitis in Repeated UTI - Doctor's Guide,
10/21/02
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Extended-Release Ciprofloxacin Safe, Effective in Urinary Tract Infections
- Doctor's Guide, 10/7/02
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Immuno-Active E. Coli Fractions Prevent Recurrent Urinary Tract Infections
- Doctor's Guide, 8/20/02
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Short Antibiotic Course Controls Paediatric Urinary Tract Infection -
Doctor's Guide, 8/5/02
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Spermicide Coated Condoms Increases Urinary Tract Infection Rates Among
Women - Doctor's Guide, 7/29/02
- Children With UTI
Need Longer Antibiotic Course - Medscape, 5/9/02
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Risk Factors in Upper Urinary Tract Infection Caused by E. Coli -
Doctor's Guide, 4/8/02
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Transvaginal Ultrasonography Detects Uterine Myomas - Doctor's Guide,
4/8/02
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Oral Treatment As Safe, Effective As Intravenous For Paediatric Febrile
Urinary Tract Infection - Doctor's Guide, 3/26/02
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Urine Dipstick Cannot Replace Microscopy to Predict UTI - Doctor's
Guide, 3/18/02
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MDs Neglect Some Guidelines - Intelihealth, 1/14/02
- Cipro (Ciprofloxacin)
Remains Most Active In Fighting Urinary Tract Infections - Doctor's
Guide, 12/19/01
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New Vaccine Prevents Urinary Infection - Intelihealth, 12/18/01
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E. Coli Linked To Urinary Infection - Intelihealth, 10/4/01
- Cefixime Safe For Children
With Relapsing Urinary Tract Infection - Doctor's Guide, 7/3/01
- New Prescription Treatment
Available For Uncomplicated Urinary Tract Infection - Doctor's Guide,
12/21/98
- First One-Dose Treatment
for Uncomplicated UTIs in Women Now Available - Doctor's Guide, 4/30/97
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