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Bromelain

Specific Recommendations:

• Bromelain at Amazon.com and iHerb

• Wobenzym / enzymes

• Supplement Use in Sickness and in Health - WebMD, 5/24/04 - "Bromelain is an anti-inflammatory [that] prevents soft tissue swelling, and decreases various markers of pain and inflammation ... In one study of 74 boxers, 80% of minor injuries from bruising and swelling cleared in just four days in those boxers who took bromelain supplements after a big fight, compared with only 14% clearing of minor injuries in those who took placebo"
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• New Mechanisms of Bromelain in Alleviating Non-Alcoholic Fatty Liver Disease-Induced Deregulation of Blood Coagulation - Nutrients 2022 Jun 1 - "Bromelain, an enzyme extracted from the stems of pineapples, exerts anticoagulant effects; however, the regulatory mechanisms are not fully understood ... these findings suggest that bromelain exerts anticoagulant effects on NAFLD-induced deregulation of coagulation by inhibiting the activation of the coagulation cascade, decreasing the stability of clots, and promoting fibrinolytic activity. The present study provides new insights into the potential therapeutic value of bromelain for the prevention and treatment of thrombosis-related diseases" - See bromelain at Amazon.com.
• Combined anthocyanins and bromelain supplement improves endothelial function and skeletal muscle oxygenation status in adults: a double-blind placebo-controlled randomised crossover clinical trial - Br J Nutr 2020 Jul 14 - "Anthocyanins and bromelain have gained significant attention due to their antioxidative and anti-inflammatory properties. Both have been shown to improve endothelial function, blood pressure (BP) and oxygen utility capacity in humans; however, the combination of these two and the impacts on endothelial function, BP, total antioxidant capacity (TAC) and oxygen utility capacity have not been previously investigated ... bromelain supplement (BE) ... flow-mediated dilation (FMD) ... The BE group showed significantly increased FMD, reduced systolic BP and improved oxygen utility capacity compared with the placebo group (P < 0·05). Tissue saturation and oxygenated Hb significantly increased following BE intake, while deoxygenated Hb significantly decreased (P < 0·05) during exercise. Additionally, TAC was significantly increased following BE intake (P < 0·05). There were no significant differences for resting heart rate, diastolic BP or fatigability index. These results suggest that BE intake is an effective nutritional therapy for improving endothelial function, BP, TAC and oxygen utility capacity, which may be beneficial to support vascular health in humans" - [Nutra USA] - See anthocyanins at Amazon.com and iHerb and bromelain at Amazon.com and iHerb.
• Supplement Use in Sickness and in Health - WebMD, 5/24/04 - "Bromelain is an anti-inflammatory [that] prevents soft tissue swelling, and decreases various markers of pain and inflammation ... In one study of 74 boxers, 80% of minor injuries from bruising and swelling cleared in just four days in those boxers who took bromelain supplements after a big fight, compared with only 14% clearing of minor injuries in those who took placebo"