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Recent Longevity News for the seven days ending 8/27/08. You should consult your doctor if you are taking any medications. Broccoli Could Reverse The Heart Damaging Effects Of Diabetes - Science Daily, 8/26/08 - "Our study suggests that compounds such as Sulforaphane from broccoli may help counter processes linked to the development of vascular disease in diabetes" Rice bran contains high arsenic levels, study - Nutra USA, 8/26/08 - "rice bran and rice bran solubles contain inorganic arsenic levels of around 1mg/kg dry weight, which is around 10-20 times the concentration found in bulk grain ... The tests were conducted on four bran solubles, one defatted bran, one riceo-ex and three bran products ... Out of the bran solubles, testing found the highest inorganic arsenic level of 0.86mg/kg in a sample from Holistic Enterprises, Santa Ana, USA. A sample from NutraCea, USA was found to contain 0.82mg/kg. A sample from Pure Planet Products, Long Beach, CA, USA, contained 0.71mg/kg and one from Integris, RiSO Triene, USA, contained 0.61mg/kg ... The rice bran products tested were from: General Dietary, UK & Eire; The Barry Farm, Ohio, USA; and Tsuno Rice Fine Chemicals Co, Japan. They contained levels of 0.48, 0.64 and 1.65mg/kg respectively ... The defatted bran and the riceo-ex products were again sourced from Japan’s Tsuno Rice, and contained 1.16 and 1.88mg/kg respectively" - That doesn't help me out much. I've been getting the Tinkyada brown rice noodles at Henry's. Rickets and Vitamin D Deficiency May Lurk in Breastfed Babies - New York Times, 8/25/08 - "Some experts fear that vitamin D deficiency, which can be asymptomatic, may be more common than pediatricians realize and that rickets — perceived to be a 19th-century scourge that was wiped out with the fortification of milk — may be going undetected ... Physicians have known for more than a century that exclusive breast-feeding may be associated with vitamin D deficiency and rickets, and that the condition is easily prevented and treated with inexpensive vitamin drops or cod liver oil. But doctors are reluctant to say anything that might discourage breast-feeding" MSG Use Is Linked to Obesity - New York Times, 8/25/08 - "After controlling for body mass index, smoking, physical activity and almost two dozen measures of daily nutrient intake, they found that the one-third of people who used the most MSG were almost three times as likely to be overweight — that is, to have a body mass index over 25 — as those who used none" How Diet, Antioxidants Prevent Blindness In Aging Population - Science Daily, 8/25/08 - "They found antioxidants disrupt the link and extend the lifetime of irreplaceable photoreceptors and other retinal cells ... The implication is that people at risk of macular degeneration could help prevent the disease by consuming antioxidants ... The experiments performed with visual cells from rats, cows and humans showed that antioxidants could completely counter the damage"
Mushroom extract demonstrates immunity benefits - Nutra USA, 8/25/08 -
"measured the production of two cytokines – Interferon
(IFN-y) and Tumor Necrosis Factor (TNF-a) – for 30 and 60 days ... These
cytokines are produced by white blood cells and used by the body to prevent the
growth of
abnormal and cancerous cells
... the production of IFN-y and TNF-a increased within four weeks of taking the
recommended of
AHCC and continued to
boost the immune system for at least four weeks after AHCC consumption stopped"
- See
AHCC at Amazon.com Burning incense linked to respiratory cancers - MSNBC, 8/25/08 - "Constant users were 80 percent more likely to develop disease" Hormone Replacement Therapy Improves Sleep, Sexuality And Joint Pain In Older Women - Science Daily, 8/21/08 - "post-menopausal women on HRT gain significant improvements in quality of life ... For most women with significant menopause symptoms the benefits of HRT outweigh the risks. The latest analyses of the main long-term randomized control trial of HRT (The Women's Health Initiative) show that breast cancer is not increased by oestrogen-only HRT and is only increased in women using combined oestrogen and progestogen HRT after seven years of use. This increased risk is less than 0.1% per year of use"
Vitamin D deficiency increases hip fracture risk: researchers - Nutra
USA, 8/20/08 - "women with the lowest 25(OH)
vitamin D concentrations (47.6 nmol/L) at study
entry had a significantly greater increased risk for subsequent
hip fracture during the next seven years than did women with the highest
concentrations (70.7 nmol/L)" - [Abstract]
- See
vitamin D at Amazon.com Abstracts from this week's Doctor's Guide Nutrition/Dietetics plus abstracts from my RSS feeds (Click here for the journals, the PubMed ones at the top):
The role of parenteral
glutamine supplement for surgical patient perioperatively: result of a single
center, prospective and controlled study - Langenbecks Arch Surg. 2008 Aug
20 - "In terms of morbidity, there was no difference
between the two groups, but two patients in the control group had wound
infection; none was noted in the Gln group (p
= 1.0). No surgical mortality was noted in this study. CONCLUSIONS:
Perioperative parenteral nutrition supplemented with Gln is beneficial for
patients undergoing GI surgery. Gln supplementation significantly attenuated
postoperative inflammation and ameliorated postoperative immunodepression as
well as nutritional depression in GI surgery"
- See
L-glutamine at Amazon.com Comparison of the effects of telmisartan and olmesartan on home blood pressure, glucose, and lipid profiles in patients with hypertension, chronic heart failure, and metabolic syndrome - Hypertens Res. 2008 May;31(5):921-9 - "telmisartan had more beneficial effects on glucose and lipid profiles in patients with relatively high HbA1c, serum total and low-density lipoprotein cholesterol, and triglyceride levels. Therefore, we concluded that telmisartan was more beneficial than olmesartan for controlling blood pressure in the early morning, as well as for improving glucose and lipid profiles in patients with hypertension, chronic heart failure, and metabolic syndrome" - Click here for why I feel that telmisartan should be the first line treatment for hypertension.
Resveratrol, at
concentrations attainable with moderate wine consumption, stimulates human
platelet nitric oxide production - J Nutr. 2008 Sep;138(9):1602-8 -
"resveratrol, at
concentrations attainable after moderate wine intake, activates platelet eNOS
and in this way blunts the proinflammatory pathway linked to p38MAPK, thus
inhibiting ROS production and ultimately platelet function. This activity may
contribute to the beneficial effects of moderate wine intake on ischemic
cardiovascular disease" - See
resveratrol products at Amazon.com
The major green tea
polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic
syndrome, and Fatty liver disease in high-fat-fed mice - J Nutr. 2008
Sep;138(9):1677-83 - "In mice fed a high-fat diet (60%
energy as fat), supplementation with dietary EGCG
treatment (3.2 g/kg diet) for 16 wk reduced body weight (BW) gain, percent body
fat, and visceral fat weight (P < 0.05) compared with mice without EGCG
treatment ... EGCG treatment attenuated insulin resistance, plasma cholesterol,
and monocyte chemoattractant protein concentrations in high-fat-fed mice (P <
0.05). EGCG treatment also decreased liver weight, liver triglycerides, and
plasma alanine aminotransferase concentrations in high-fat-fed mice (P < 0.05).
Histological analyses of liver samples revealed decreased lipid accumulation in
hepatocytes in mice treated with EGCG compared with high-fat diet-fed mice
without EGCG treatment. In another experiment, 3-mo-old high-fat-induced obese
mice receiving short-term EGCG treatment (3.2 g/kg diet, 4 wk) had decreased
mesenteric fat weight and blood glucose compared with high-fat-fed control mice
(P < 0.05). Our results indicate that long-term EGCG treatment attenuated the
development of obesity, symptoms associated with the
metabolic syndrome, and fatty liver. Short-term
EGCG treatment appeared to reverse preexisting high-fat-induced metabolic
pathologies in obese mice. These effects may be mediated by decreased lipid
absorption, decreased inflammation, and other mechanisms" - See
green tea extract at Amazon.com Telmisartan prevented cognitive decline partly due to PPAR-gamma activation - Biochem Biophys Res Commun. 2008 Aug 17 - "Pretreatment with a non-hypotensive dose of telmisartan significantly inhibited such cognitive decline. Interestingly, co-treatment with GW9662, a PPAR-gamma antagonist, partially inhibited this improvement of cognitive decline. Another ARB, losartan, which has less PPAR-gamma agonistic effect, also inhibited Abeta-injection-induced cognitive decline; however the effect was smaller than that of telmisartan and was not affected by GW9662. Immunohistochemical staining for Abeta showed the reduced Abeta deposition in telmisartan-treated mice. However, this reduction was not observed in mice co-administered GW9662. These findings suggest that ARB has a preventive effect on cognitive impairment in Alzheimer disease, and telmisartan, with PPAR-gamma activation, could exert a stronger effect"
Vitamin D intake and
breast cancer risk: a case-control study in Italy - Ann Oncol. 2008 Aug 18 -
"The OR for subjects in the three highest deciles of
consumption compared with those in the lowest ones combined was 0.79 (95% CI
0.70-0.90). Intake of vitamin D >3.57 mug or 143 IU appeared to have a
protective effect against breast cancer. The
inverse association was consistent across strata of menopausal status ... This
study adds to the existing evidence that vitamin D
intake in inversely associated with breast cancer risk" - See
vitamin D at Amazon.com Antioxidant treatment with alpha-tocopherol improves erectile function in hypertensive rats - Hypertens Res. 2008 May;31(5):1007-13 - "Treatment with 24 mg alpha-tocopherol decreased TBARS levels and increased SOD activity in the serum and corpus cavernosum. Relaxation in response to acetylcholine chloride in the corpus cavernosum was improved with alpha-tocopherol treatment at each dose. These results suggest that alpha-tocopherol treatment increases the diminished relaxation in the corpus cavernosum of SHRs by improving neuronal or endothelial function related to nitric oxide and carbon monoxide. This, in turn, indicates that antioxidant therapy may play a role in treatment for ED in hypertensive patients" Coffee consumption and risk of coronary heart diseases: A meta-analysis of 21 prospective cohort studies - Int J Cardiol. 2008 Aug 14 - "Our findings do not support the hypothesis that coffee consumption increases the long-term risk of coronary heart disease. Habitual moderate coffee drinking was associated with a lower risk of CHD in women"
Serum 25-hydroxyvitamin D
concentrations and risk for hip fractures - Ann Intern Med. 2008 Aug
19;149(4):242-50 - "Low serum 25(OH)
vitamin D concentrations are associated with a higher risk for
hip fracture" - [Nutra
USA] - See
vitamin D at Amazon.com Coffee consumption and risk of endometrial cancer: A prospective study in Japan - Int J Cancer. 2008 Aug 18 - "After adjustment for age, study area, body mass index, menopausal status, age at menopause for postmenopausal women, parity, use of exogenous female hormones, smoking status and by consumption of green vegetables, beef, pork and green tea, the multivariate HRs (95% CI) of endometrial cancer in women who drank coffee </=2 days/week, 3-4 days/week, 1-2 cups/day and >/=3 cups/day were 1.00, 0.97 (0.56-1.68), 0.61 (0.39-0.97) and 0.38 (0.16-0.91), respectively ... Coffee consumption may be associated with a decreased risk of endometrial cancer" Flaxseed oil prevents trans-10, cis-12-conjugated linoleic acid-induced insulin resistance in mice - Br J Nutr. 2008 Aug 19:1-8 - "The present results suggest that some adverse effects of CLA may be due to n-3 PUFA deficiency and that these can be corrected by a concomitant increase in the intake of alpha-linolenic acid, 18 : 3n-3" - Note: There are different isomers of CLA, some improve and some worsen insulin resistance. The most popular brand of CLA is Tonalin. That's what I take but I haven't been able to figure out if that's one that improves or worsens insulin resistance.
Health Focus (White Blood Cells): Alternative News on White Blood Cells:
Other News on White Blood Cells:
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