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Attention-Deficit/Hyperactivity Disorder (ADHD)

Popular Drugs:

• Adderall (amphetamine dextroamphetamine) / Provigil (modafinil) / Ritalin (Methylphenidate) / Strattera (atomoxetine) / Vyvanse (lisdexamfetamine) / Wellbutrin (bupropion)

Popular Supplements:

• Omega-3 / phosphatidylserine (PS) / zinc / magnesium / iron / 5-HTP / B vitamins / L-tyrosine / L-phenylalanine / melatonin / Vitamin C / proanthocyanidins

Alternative News:

• Complementary effects of pine bark extract supplementation on inattention, impulsivity, and antioxidative status in children with attention-deficit hyperactivity disorder: A double-blinded randomized placebo-controlled cross-over study - Phytother Res 2021 Feb 8 - "The purpose of this study was to investigate the complementary effects of polyphenolic compounds from pine bark extract (PE) as a strong antioxidative substrate on the symptoms of inattention and impulsivity in children with attention-deficit hyperactivity disorder (ADHD) ... PE supplementation caused a significant reduction in the inattention and hyperactivity-impulsivity items of SNAP-IV. During the period of PE supplementation, the item of commissions in the Continuous Performance Test III (CPT III) significantly decreased, which was used to evaluate the symptoms of inattention and impulsivity. In addition, the erythrocytic reduced glutathione/oxidized glutathione ratio significantly increased, and the plasma TBARs level significantly decreased after 4 weeks of PE supplementation. However, there was no significant correlation between CPT III (commission) and antioxidative status indictors. PE supplementation may have potential effects of ameliorating inattention and impulsivity, and elevating the antioxidative status in children with ADHD" - See pine bark extract at Amazon.com.
• Vitamin D deficiency during pregnancy connected to elevated risk of ADHD - Science Daily, 2/10/20 - "despite the recommendations, vitamin D deficiency is still a global problem ... This research offers strong evidence that a low level of vitamin D during pregnancy is related to attention deficiency in offspring. As ADHD is one of the most common chronic diseases in children, the research results have a great significance for public health" - See vitamin D at Amazon.com.
• High-dose eicosapentaenoic acid (EPA) improves attention and vigilance in children and adolescents with attention deficit hyperactivity disorder (ADHD) and low endogenous EPA levels - Transl Psychiatry. 2019 Nov 20;9(1):303 - "EPA treatment improves cognitive symptoms in ADHD youth, especially if they have a low baseline endogenous EPA level, while youth with high EPA levels may be negatively affected by this treatment" - [Nutra USA] - See omega-3 supplements at Amazon.com.
• Supplementation with high-content docosahexaenoic acid triglyceride in attention-deficit hyperactivity disorder: a randomized double-blind placebo-controlled trial - Neuropsychiatr Dis Treat. 2019 May 8 - "This study provides further evidence of the beneficial effect of supplementation with ω-3 DHA in the management of ADHD" - [Nutra USA] - See docosahexaenoic acid at Amazon.com.
• Reduced Symptoms of Inattention after Dietary Omega-3 Fatty Acid Supplementation in Boys with and without Attention Deficit/Hyperactivity Disorder - Neuropsychopharmacology. 2015 Sep - "Participants consumed 10 g of margarine daily, enriched with either 650 mg of eicosapentaenoic acid (EPA)/docosahexaenoic acid (DHA) each or placebo ... EPA/DHA supplementation improved parent-rated attention in both children with ADHD and typically developing children ... EPA/DHA supplementation improved parent-rated attention in both children with ADHD and typically developing children ... this study offers support that omega-3 supplementation may be an effective augmentation for pharmacological treatments of ADHD" - [Nutra USA] - See fish oil supplements at Amazon.com.
• Micronutrient Supplement May Ease Adult ADHD, Boost Mood - Medscape, 1/30/14 - "The study involved 80 adults with untreated ADHD. For 8 weeks, 42 took the micronutrient supplement (15 capsules per day, in 3 doses of 5 capsules, taken with food and water), and 38 took matching placebo ... the micronutrient treatment induced "statistically robust improvements in several indices, from ADHD symptoms to global assessment of functioning, compared with placebo, with effect sizes ranging from 0.46 to 0.67." ... Minerals and vitamins work in synergy, and combinations are often required for the body to utilize to perform many neurochemical activities (such as those that influence maintaining concentration or mood)"
• Omega-3 reduces ADHD symptoms in rats - Science Daily, 8/23/13 - "The results show a clear improvement in ADHD-related behaviour from supplements of omega-3 fatty acids, as well as a faster turnover of the signal substances dopamine, serotonin and glutamate in the nervous system ... The new findings indicate that ADHD has a biological component and that the intake of omega-3 may influence ADHD symptoms ... we have without a doubt found molecular changes in the brain after rats with ADHD were given omega-3 ... We saw that the turnover of dopamine and serotonin took place much faster among the male rats that had been given omega-3 than among those that had not. For serotonin the turnover ratio was three times higher, and for dopamine it was just over two and a half times higher" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• Low Omega-3 in Kids Linked to Behavior, Cognitive Deficits - Medscape, 7/23/13 - "This study formed the screening stage of a previously published randomized controlled intervention study that included 362 healthy children aged 7 to 9 years from primary schools in Oxfordshire, a large county in the UK, who had low reading scores. The DOLAB study reported that supplementation with 600 mg DHA daily for 16 weeks improved reading and behavior in children with the lowest 20% of reading scores ... The study showed that reading scores were significantly and positively associated with the omega-3 fatty acids DHA (P < .003), docosapentaenoic acid (DPA; P < .04), eicosapentaenoic acid (EPA; P < .005), and the omega-3 index (EPA+DHA; P < .04). Total omega-6 fatty acids also showed a positive correlation with reading ... Results were similar for working memory. Scores for Recall of Digits Forward were significantly and positively associated with DHA (P < .003), DPA (P < .04), EPA (P < .005), the omega-3 index (P < .001), and total omega-3 (P < .004)" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
• Vitamin B: Choline intake improves memory and attention-holding capacity, experts say - Science Daily, 7/11/13 - "In the first experiment, scientists administered choline to rats during the third term of gestation ... the scientists concluded that prenatal choline intake improves long-term memory in the resulting offspring once they reach adulthood ... In the second experiment, the researchers measured changes in attention that occurred in adult rats fed a choline supplement for 12 weeks, versus those with no choline intake. They found that the rats which had ingested choline maintained better attention that the others when presented with a familiar stimulus" - See citicholine at Amazon.com.
• Iron supplements reduce ADHD in low birth weight infants - Science Daily, 12/10/12 - "researchers in Sweden gave 285 marginally low birth weight infants either 0, 1 or 2 mg/kg and day of iron supplements from 6 weeks to 6 months of age. At age three-and-a-half, these infants and 95 who had a normal birth weight were assessed for intelligence and behavior. There were no significant differences in IQ between the low birth weight groups and the normal-weight control group. However, for behavioral problems like ADHD, there was a significant effect from the iron supplements. Of the low birth weight infants who received no iron supplements, 12.7 percent showed signs of behavior problems, compared to 2.9 percent of infants in the 1-mg group and 2.7 percent of the 2-mg group. In the control group, 3.2 percent of children showed signs of behavioral problems"
• Omega-3 Effective for Treating Child ADHD - Medscape, 9/8/11 - "In an evaluation of 10 trials with 699 total children with ADHD, investigators found that those who received omega-3 supplements had a "small but significant" improvement in symptom severity compared with those who were given placebo. This effect was also significant in the children who received supplements that specifically contained higher doses of eicosapentaenoic acid ... Omega-3 supplements that included higher doses of eicosapentaenoic acid were also significantly associated with lowering ADHD symptoms ... There were no significant differences found for any dose of docosahexaenoic acid or α-linolenic acid, or between omega-3 monotherapy vs augmenting traditional ADHD medications with omega-3" - See Mega Twin EPA at Amazon.com.
• Ritalin may ease early iron deficiency damage - Science Daily, 2/2/11 - "When children are deprived of iron at any point during the last trimester of pregnancy or the first six months of life -- a critical period of brain development -- they suffer brain damage at least through early adulthood, and possibly beyond. In particular, their motor function can be impaired as well as their ability to focus ... Iron-deficient adults often have restless leg syndrome. People who become iron deficient after three years of age can recover by taking iron supplements ... iron deficiency has a major hit on dopamine systems" - See Slow Fe Slow Release Iron Tablets 90-Count Box at Amazon.com.
• Serum ferritin and amphetamine response in youth with attention-deficit/hyperactivity disorder - J Child Adolesc Psychopharmacol. 2010 Dec;20(6):495-502 - "Their ADHD symptoms were moderately severe at baseline (SNAP item mean = 2.1). Their mean ferritin concentration was 18.4 ng/mL, with 23% of the participants having a level below 7, the assay-defined threshold for ID. Serum ferritin was inversely correlated with baseline inattention, hyperactivity/impulsivity, and total ADHD symptom scores (Partial Spearman's r = -0.31, p = 0.04; r = -0.42, p < 0.006; and r = -0.43, p < 0.004, respectively) and with the weight-adjusted dose of amphetamine used to optimize clinical response (Partial Spearman's r = -0.45, p < 0.007). Psychotropic-treatment history moderated some, but not all, of these associations, with previously medicated children showing a stronger association between ferritin concentration and ADHD symptom severity" - See Slow Fe Slow Release Iron Tablets 90-Count Box.
• Supplementation of polyunsaturated fatty acids, magnesium and zinc in children seeking medical advice for attention-deficit/hyperactivity problems - an observational cohort study - Lipids Health Dis. 2010 Sep 24;9(1):105 - "After 12 weeks of consumption of a combination of omega-3 and omega-6 fatty acids as well as magnesium and zinc most subjects showed a considerable reduction in symptoms of attention deficit and hyperactivity/impulsivity assessed by SNAP-IV. Further, the assessment by SDQ revealed fewer emotional problems at the end of the study period compared to baseline and also sleeping disorders. Mainly problems to fall asleep, decreased during the 12 week nutritional therapy" - Note:  If it were me I'd skip the omega-6.  Most people get way too much as it is.
• EPA supplementation improves teacher rated behaviour and oppositional symptoms in children with ADHD - Acta Paediatr. 2010 May 19 - "Two ADHD subgroups (oppositional and less hyperactive/impulsive children) improved after 15 weeks EPA treatment. Increasing EPA and decreasing omega-6 fatty acid concentrations in phospholipids were related to clinical improvement" - See Mega Twin EPA at Amazon.com.
• Tea compounds may boost attention span: Unilever - Nutra USA, 1/19/10 - "This study provided further evidence that the L-theanine/caffeine combination improves attention on the switch task ... The improvement in accuracy in combination with unaltered response speed is in line with previous studies ... Tentative evidence was [also] found that the effect of the L-theanine/caffeine combination on attention is not specific to the visual modality, as we found faster responses in both the visual and auditory modality on the intersensory task after the combination as compared to placebo ... Taken together with the previous studies, we conclude that a high dose of L-theanine combined with caffeine, at the level of a single cup of tea, can help to improve attention" - [Abstract] - See theanine at Amazon.com.
• L-theanine and caffeine improve task switching but not intersensory attention or subjective alertness - Appetite. 2010 Jan 13 - "The results support previous evidence that L-theanine and caffeine in combination can improve attention" - See Jarrow Formulas, Theanine 200.
• Melatonin Treatment for Insomnia in Pediatric Patients with Attention-Deficit/Hyperactivity Disorder (January) - Ann Pharmacother. 2009 Dec 22 - "Available data suggest that melatonin is a well-tolerated and efficacious treatment option for pediatric patients with chronic SOI and ADHD" - See melatonin at Amazon.com.
• New study links DHA type of omega-3 to better nervous-system function - Science Daily, 12/16/09 - "The omega-3 essential fatty acids commonly found in fatty fish and algae help animals avoid sensory overload ... The finding connects low omega-3s to the information-processing problems found in people with schizophrenia; bipolar, obsessive-compulsive, and attention-deficit hyperactivity disorders; Huntington's disease; and other afflictions of the nervous system" - See Jarrow Max DHA at Amazon.com.
• Children With ADHD at Risk for Zinc and Copper Deficiency - Medscape, 11/3/09 - "this patient population is at risk for low trace mineral status, including deficiencies in zinc and copper — minerals that may play a crucial role in the production of dopamine, norepinephrine, and melatonin, which regulates sleep ... Presented here at the American Academy of Child & Adolescent Psychiatry 56th Annual Meeting, a study conducted by investigators at the University of British Columbia and the Children's and Women's Health Centre in Vancouver, Canada, showed among 44 children aged 6 to 12 years with ADHD, rates of zinc and copper deficiency were 45% and 35%, respectively" - See Jarrow Zinc Balance at Amazon.com.
• Attention-deficit/hyperactivity Problems Associated With Low Folate Levels In Pregnant Women - Science Daily, 10/28/09 - "A study published in an upcoming issue of The Journal of Child Psychology and Psychiatry finds that low maternal folate levels is linked to the development of attention-deficit/hyperactivity problems in children at age seven to nine years"
• Multivitamins and minerals help children's brain function: study - Nutra USA, 11/5/08 - "the children in the vitamin/mineral group performed more accurately on two tests of attention. Indeed, the researchers noted the first signs of improvement only three hours after the first dose on the first day" - [Abstract]
• Multivitamins and minerals help children's brain function: study - Br J Nutr. 2008 Nov;100(5):1086-96 - "these results would seem to suggest that vitamin/mineral supplementation has the potential to improve brain function in healthy children"
• Omega-3 carrier key to boosting children's attention: study - Nutra USA, 5/15/08 - "Test of Variables of Attention (TOVA) scores ... In terms of attention measures, both omega-3 supplemented groups produced increased in TOVA scores, with an increase of 94 per cent in the PL-omega-3 group and 37 per cent in the fish oil group" - [Abstract] - See Mega Twin EPA at Amazon.com.
• Correlation between changes in blood fatty acid composition and visual sustained attention performance in children with inattention: effect of dietary n-3 fatty acids containing phospholipids - Am J Clin Nutr. 2008 May;87(5):1170-80 - "Test of Variables of Attention; TOVA ... Total TOVA scores increased in the PL-n-3 (mean +/- SD: 3.35 +/- 1.86) and FO (1.72 +/- 1.67) groups but not in the placebo group (-0.42 +/- 2.51) (PL-n-3 > FO > placebo; P < 0.001). A significant correlation between the alterations in FAs and increased TOVA scores mainly occurred in the PL-n-3 group"
• L-Acetylcarnitine Curbs ADHD Associated With Fragile X Syndrome - Medscape, 3/12/08 - "L-acetylcarnitine (LAC) may be considered an alternative to stimulants for the treatment of attention deficit hyperactivity disorder (ADHD) in children with fragile X syndrome, based on results of a double-blind, placebo-controlled study" - See acetyl l-carnitine products at Amazon.com.
• Fatty acid status and behavioural symptoms of Attention Deficit Hyperactivity Disorder in adolescents: A case-control study - Nutr J. 2008 Feb 14;7(1):8 - "ADHD adolescents consumed more energy and fat than controls but had similar anthropometry. ADHD children consumed equivalent amounts of omega-3 and omega-6 fatty acids to controls, however they had significantly lower levels of docosahexaenoic acid (DHA, 22:6n-3) and total omega-3 fatty acids, higher omega-6 fatty acids and a lower ratio of n-3:n-6 fatty acids than control subjects. In addition, low omega-3 status correlated with higher scores on several Conners' behavioural scales ... These data suggest that adolescents with ADHD continue to display abnormal essential fatty acid profiles that are often observed in younger children and distinctly different from normal controls of similar age. Further these red blood cell fatty acid differences are not explained by differences in intake. This suggests that there are metabolic differences in fatty acid handling between ADHD adolescents and normal controls. The value of omega-3 supplements to improve fatty acid profiles and possibly behaviours associated with ADHD, need to be examined" - See Jarrow Max DHA at Amazon.com and Mega Twin EPA at Amazon.com.
• Effects of an open-label pilot study with high-dose EPA/DHA concentrates on plasma phospholipids and behavior in children with attention deficit hyperactivity disorder - Nutr J. 2007 Jul 13;6(1):16 - "Nine children were initially supplemented with 16.2g EPA/DHA concentrates per day. The dosage was adjusted dependent on the ratio of arachidonic acid (AA) to EPA in the isolated plasma phospholipids at four weeks to reach a level normally found in the Japanese population ... A psychiatrist (blind to supplement compliance or dosage modifications) reported significant improvements in behavior (inattention, hyperactivity, oppositional/defiant behavior, and conduct disorder). There was also a significant correlation between the reduction in the AA:EPA ratio and global severity of illness scores" - See Mega Twin EPA at Amazon.com.
• Fish Oil for ADHD? - Dr. Weil, 8/7/06
• More support for omega-3 calming ADHD kids - Nutra USA, 6/22/06
• Pine Bark Extract May Effectively Treat ADHD in Boys - Medscape, 6/23/06 - "61 children with ADHD were randomized 2:1 to receive 1 mg/kg/day pine bark extract or placebo for 4 weeks. Average age was 9.5 years ... The pine bark extract group had a significant reduction in hyperactivity and improved attention, visual-motor coordination, and concentration, whereas there were no positive effects noted in the placebo group" - See iHerb Pycnogenol products.
• Treatment of ADHD with French maritime pine bark extract, Pycnogenol - Eur Child Adolesc Psychiatry. 2006 Sep;15(6):329-35 - "1-month Pycnogenol administration caused a significant reduction of hyperactivity, improves attention and visual-motoric coordination and concentration of children with ADHD. In the placebo group no positive effects were found. One month after termination of Pycnogenol administration a relapse of symptoms was noted. Our results point to an option to use Pycnogenol as a natural supplement to relieve ADHD symptoms of children" - See iHerb Pycnogenol products.
• Omega-3 fatty acids in ADHD and related neurodevelopmental disorders - Int Rev Psychiatry. 2006 Apr;18(2):155-72 - "Dietary supplementation with fish oils (providing EPA and DHA) appears to alleviate ADHD-related symptoms in at least some children, and one study of DCD children also found benefits for academic achievement" - See Mega Twin EPA at iHerb.
• ADHD teens calmed by omega oils - Nutra USA, 3/28/06
• Advances in Nutritional Therapy for Attention Deficit Hyperactivity Disorder - Life Extension Magazine, 7/05
• Study Links Low Iron to ADHD - WebMD, 12/17/04 - "Low iron levels in the brain are known to alter the activity of dopamine, a chemical involved in controlling movement. The researchers suggest that this could explain the observed link between iron stores and ADHD"
• Iron Supplementation May Help Children With ADHD - Medscape, 12/6/04 - "Iron deficiency has been previously considered a potent cause of poor cognitive impairment, learning disability, and psychomotor instability ... ferritin levels were significantly lower in children with ADHD"
• Treating Attention Deficit Disorder in Adults? - Dr. Weil, 6/7/04
• Distracted Young Women May Need More Iron - Intelihealth, 4/28/04 - "Women in the Penn State study who were iron-deficient performed significantly worse on memory and attention tests than healthy women, and an iron supplement was all it took to correct the problem" - See iron supplements at Amazon.com.
• Reducing Anxiety Related to ADHD? - Dr. Weil, 4/13/04
• Zinc to underpin ADHD treatment? - Nutra USA, 4/8/04 - "Zinc supplements could increase the effectiveness of stimulants used to treat children with attention deficit hyperactivity disorder"
• Melatonin Helpful for Delayed Sleep Onset in Children With ADHD - Medscape, 10/21/03
• Phospholipids: Versatile Nutraceutical Ingredients For Functional Foods - Functional Foods & Nutraceuticals, 12/02 - "Ryser concluded that PS yielded clinically significant benefit to 25 of the 27 children. PS improved attention, concentration, learning, behaviour and academic performance, seemingly extending their level of benefit once they had "plateaued" on fish oil and other nutritional supplements. Those prescribed methylphenidate (Ritalin) or other pharmaceuticals also seemed to derive additional benefit from PS which also benefited the depression and anxiety commonly seen in these children" - See iHerb PS products.
• Herbs for ADD? - Dr. Weil, 10/8/02 - "Dr. Newmark does recommend a dietary supplement, omega-3 fatty acids, for all children with ADHD because levels of omega-3s in the plasma and red blood cells of children with ADHD are lower than in normal children"
• L-Carnitine Effective for Attention Deficit-Hyperactivity Disorder - New Hope Natural Media, 12/19/02 - "According to the parents’ ratings, 54% of the children showed significant improvement in their behavior while taking L-carnitine, whereas only 13% improved during the placebo period. The teachers’ ratings showed a similar, though slightly less pronounced, advantage of L-carnitine over placebo" - See l-carnitine at Amazon.com.  Also see acetyl-l-carnitine.
• Essential Fatty Acids Improve Thought Process and Behavior in Children with ADHD - New Hope Natural Media Online, 6/13/02 - "ADHD is characterized by impulsive behavior, lack of concentration, restlessness and, in some cases, learning disabilities ... The children were given either a supplement containing 186 mg of eicosapentaenoic acid (EPA), 480 mg of docosahexaenoic acid (DHA), 96 mg of gamma-linolenic acid (GLA), 864 mg of linoleic acid, and 60 IU of vitamin E per day, or a placebo ... the children who took the essential fatty acid supplement had significant improvement in symptom scores related to learning and behavior"
• Omega 3: Implications in human health and disease - PowerPak (39 page CME course for Registered Dietitians), exp. 8/1/03 - "In 53 ADHD patients, Burgess reported significant deficits of PUFA, including EPA and DHA, in plasma and red blood cell lipids.179 Twenty-one of these patients exhibited symptoms of EFA deficiency, including dry skin and hair abnormalities, increased thirst and urination, and brittle nails. Subsets of the ADHD population with lower compositions of blood lipid omega 3 had significantly more behavioral problems (including temper tantrums) and learning, health, and sleep-related problems than subjects with higher levels of omega 3"
• Many Parents Use Alternative Therapies for ADHD - Clinical Psychiatry News, 4/02
• Can Fructose Trigger Hyperactivity in Kids? - Dr. Weil, 2/26/02
• Dietary Supplement [docosahexaenoic acid] Not Effective in Treating ADHD - WebMD, 8/16/01
• Be Careful of Alternative Treatments for ADHD - WebMD, 9/11/00 - "Abramowitz agrees that one dietary supplement that seems promising in the research so far is alpha omega-3 fatty acids."
• Polyunsaturated Fats and Neurological Disorders - Nutrition Science News, 9/00
• ADHD A Modern Malady - Nutrition Science News, 8/00

Other News:

• Is Immaturity Being Mistaken for ADHD? - WebMD, 3/5/12 - "Compared to children whose birthdays were in January, boys born in December were about 30% more likely to be diagnosed with ADHD. Girls born in December were 70% more likely to be diagnosed with ADHD"
• Adults with attention deficit hyperactivity disorder score high in creativity - Science Daily, 3/11/11
• ADHD Now, Dementia Later? - WebMD, 1/20/11 - "Adults with symptoms of ADHD, or attention deficit hyperactivity disorder, are more than three times as likely as other adults to develop a form of dementia later in life ... Our hypothesis is that ADHD could be the clinical result of the first step in these pathway disorders, and after a long time, this problem degenerates to a more severe pathology with structural changes in the brain, as Lewy Body Dementia is"
• Gene linked to ADHD allows memory task to be interrupted by brain regions tied to daydreaming - Science Daily, 11/16/10
• Widely used chemicals linked to ADHD in children - Science Daily, 7/20/10 - "PFCs are highly stable compounds used in industrial and commercial products like stain-resistance coatings, food packaging, and fire-fighting foams. In a 2003-2004 survey, NHANES examined 2,094 blood samples taken from the U.S. population and found more than 98 percent of the sample had detectable serum levels of PFCs, according to the study. Once absorbed into the body, it can take years for some types of PFCs to be partially eliminated ... children with this outcome tend to have higher levels of PFCs in their blood." Because the PFC measurements were collected at the same time as the parental report of ADHD diagnosis, Hoffman said it is unknown whether children with ADHD engage in behavior leading to increased PFC exposure or if higher serum PFC levels in children result in ADHD"
• Pesticide exposure may contribute to ADHD, study finds - Science Daily, 5/17/10
• Common plastics chemicals -- phthalates -- linked to ADHD symptoms - Science Daily, 11/19/09 - "Researchers found a significant positive association between phthalate exposure and ADHD, meaning that the higher the concentration of phthalate metabolites in the urine, the worse the ADHD symptoms and/or test scores"
• Deficits In Brain's Reward System Observed In ADHD Patients; Low Levels Of Dopamine Markers May Underlie Symptoms - Science Daily, 9/9/09
• ADHD Tied to Brain's Reward Pathway - WebMD, 9/8/09
• Once-Daily Guanfacine Approved to Treat ADHD - Medscape, 9/3/09 - "Guanfacine is the first selective alpha-2a adrenergic receptor agonist to be approved for treating ADHD. It is thought to exert its effects by directly engaging receptors in the prefrontal cortex to reduce susceptibility to distraction and improve working memory, attention regulation, behavioral inhibition, and impulse control"
• Stimulant Medications for ADHD and Academic Performance - Medscape, 8/10/09
• Adults With ADHD Miss More Workdays - WebMD, 5/27/08
• ADHD Drugs: Heart Screen Recommended - WebMD, 4/21/08
• Study Raises Questions About Diagnosis, Medical Treatment Of ADHD - Science Daily, 1/24/08
• Even Low Lead Exposure Linked To ADHD - Science Daily, 12/5/07
• Brain Matures A Few Years Late In ADHD, But Follows Normal Pattern - Science Daily, 11/13/07
• Preschoolers With Three or More Coexisting Disorders Show No Response to ADHD Medication Treatment - Doctor's Guide, 11/5/07
• Early Pharmacotherapy in Children With ADHD Might Reduce Risk of Comorbid Depressive Disorder - Doctor's Guide, 11/1/07
• Reducing the Symptoms of Attention-Deficit Hyperactivity Disorder Reflects Behavioural and Social Improvements - Doctor's Guide, 10/31/07
• Emerging Treatment Advances in ADHD - Physician's Weekly, 10/15/07
• Stimulant Treatment Linked With Improved Long-Term School Outcomes in ADHD - Medscape, 10/8/07 - "compared with the children with ADHD who did not receive stimulants, those who did were 1.8 times less likely to be held back a grade, and they had a lower rate of absenteeism"
• Stimulants Help Students With ADHD - WebMD, 9/20/07 - "Kids with attention deficit hyperactivity disorder (ADHD) who take Ritalin or other prescription stimulants are more likely to achieve long-term academic success than children with ADHD who don’t take drugs"
• ADHD Appears to Be Associated With Depressed Dopamine Activity in the Brain - Doctor's Guide, 8/6/07
• Medication For ADHD May Help Students Succeed At School - Science Daily, 9/18/07
• Food Additives Linked To Hyperactivity In Children, Study Shows - Science Daily, 9/9/07 - "A study by researchers at the University of Southampton has shown evidence of increased levels of hyperactivity in young children consuming mixtures of some artificial food colours and the preservative sodium benzoate"
• Treating ADHD: Drugs or Therapy Work - WebMD, 7/20/07
• Improvement Following ADHD Treatment Sustained In Most Children - Science Daily, 7/20/07
• Does Stimulant Treatment For ADHD Increase Risk Of Drug Abuse? - Science Daily, 6/18/07
• TSH concentration within the normal range is associated with cognitive function and ADHD symptoms in healthy preschoolers - Clin Endocrinol (Oxf). 2007 Jun;66(6):890-8 - "Children with TSH concentrations in the upper quartile of the normal range performed lower on McCarthy's scales and were at higher risk for attention deficit and hyperactivity/impulsivity symptoms"
• Many Children Discontinuing Use Of ADHD Medication - Science Daily, 12/17/06
• 1/3 ADHD Cases Linked to Lead, Smoking - WebMD, 9/20/06
• Parents seek ADHD meds to boost kids' grades - MSNBC, 9/7/06
• ADHD Symptoms Worsen After Years of Stable Stimulant Dose - Medscape, 8/30/06
• Modafinil for ADHD May Be Another Alternative to Stimulants - Medscape, 8/7/06
• Effects of ADHD on Employment and Household Income - Medscape, 7/18/06
• Study Reveals How ADHD Drugs Work In Brain - Science Daily, 6/26/06
• Do ADHD Drugs Stunt Kids' Growth? - WebMD, 5/1/06
• Tonsil Surgery Helps Kids With ADHD - WebMD, 4/3/06
• Functional Roles of Norepinephrine and Dopamine in ADHD - Medscape, 3/9/06
• Choose Nonstimulants With Care in ADHD - Clinical Psychiatry News, 9/05
• Smoking During Pregnancy May Double ADHD Risk - WebMD, 8/2/05
• Conduct, Bipolar Disorder Often Comorbid With ADHD - Clinical Psychiatry News, 7/05
• Antinarcolepsy Drug May Improve ADHD - Clinical Psychiatry News, 7/05
• Women With ADHD Have More Severe Symptoms Than Men - Doctor's Guide, 5/27/05
• Caffeinated Colas Linked to Inattention, Hyperactivity in First-Graders - Doctor's Guide, 5/27/05
• Workplace May Overwhelm Adults With ADHD - WebMD, 5/26/05
• Modafinil (Provigil) Pediatric Formulation Shows Early, Sustained Effects in Attention Deficit/Hyperactivity Disorder - Doctor's Guide, 5/26/05
• Adult ADHD Sufferers Face Lost Income, Jobs - WebMD, 5/25/05
• Medication Combined with Behavior Therapy Works Best for ADHD Children, Study Finds - Doctor's Guide, 5/6/05
• Should control children be given a stimulant for an ADHD study at the National Institutes of Health? - Clinical Psychiatry News, 4/6/05
• Screen ADHD Patients for Problems With Sleep - Clinical Psychiatry News, 4/05
• Novel Imaging Technique Shows Abnormal Brain Anatomy In Children With ADHD - Science Daily, 12/8/04
• Attention Deficit Disorder Grows Up - CBS Chicago, 12/5/04
• Brain Changes Seen in Kids With ADHD - WebMD, 11/29/04
• Stimulants Normalize Dysfunctional Brain Circuitry in Attention Deficit/Hyperactivity Disorder - Doctor's Guide, 11/29/04
• Sleep Disorders, Attention Problems Linked - WebMD, 10/25/04
• Study Confirms ADHD Is More Common in Boys - WebMD, 9/15/04
• ADHD Costs Adults $77 Billion in Lost Income - Doctor's Guide, 9/9/04
• Methylin Chewable Tablets and Methylin Oral Solution for Treatment of Attention Deficit Hyperactivity Disorder Launched in US - Doctor's Guide, 9/7/04
• 10-Year Study: ADHD Persists as Boys Become Men - Clinical Psychiatry News, 8/04
• Test Predicts ADHD Response to Ritalin - WebMD, 6/22/04
• Approaches, Perspectives on ADHD - Clinical Psychiatry News, 6/04
• Living with Adult ADD - US News, 4/26/04
• Bupropion XL Useful for Adult ADHD - Clinical Psychiatry News, 4/04
• The Challenge of Treating ADHD - Clinical Psychiatry News, 4/04
• Effects of ADHD Treatment May Vary Over Time - WebMD, 4/5/04
• ADHD Medication Does Not Alter Height or Weight - Clinical Psychiatry News, 2/04
• Undiagnosed ADHD Affects Millions of Adults - Clinical Psychiatry News, 2/04
• Test Parents of ADHD Kids, Too - WebMD, 1/8/04
• After-School Treatment of ADHD - WebMD, 12/19/03
• Brain Scans Reveal ADHD Differences - WebMD, 12/4/03
• ADHD focuses on adults - USA Today, 12/2/03
• Nicotine as Good as Ritalin on Core Measure of Attention Deficit/Hyperactivity Disorder - Doctor's Guide, 11/13/03
• Attention Deficit Hyperactivity Disorder Symptoms In Children Linked to Maternal Smoking - Doctor's Guide, 11/12/03
• Attention Deficit/Hyperactivity Disorder Treatments Cause Mild Blood Pressure, Heart Rate Changes in Adults - Doctor's Guide, 10/27/03
• Substance Abuse More Common In Adolescents With Untreated Compared To Treated Attention-Deficit/Hyperactivity Disorder - Doctor's Guide, 10/20/03
• Older Adolescents with Attention Deficit/Hyperactivity Disorder More Likely to Smoke - Doctor's Guide, 10/20/03
• Teachers Usually First to Report ADHD - WebMD, 9/30/03
• ADHD Linked to Later Substance Abuse - WebMD, 8/18/03
• Routine Screening Strategy Needed for ADHD in Adults - Clinical Psychiatry News, 8/03
• Adult ADHD: Breaking the Barriers to Awareness - Physician's Weekly, 7/21/03
• Adult ADHD, Bipolar Disorder May Overlap - WebMD, 7/11/03
• Modafinil Treats Core Symptoms of ADHD - Clinical Psychiatry News, 7/03
• PET, SPECT Studies Find More Evidence of Dopamine's Role in ADHD - Medscape, 6/24/03
• Transdermal MAO Inhibitor Patch Effective for ADHD - Clinical Psychiatry News, 6/03 - "A transdermal patch containing the selective monoamine oxidase inhibitor selegiline applied daily appeared effective and well tolerated in a pilot study of children and adolescents with attention-deficit hyperactivity disorder ... Selegiline is a specific monoamine oxidase (MAO) type B inhibitor, so it “is essentially devoid of the tyramine-cheese effect we think about with MAO [type A] inhibitors" - Selegiline is used my many for anti-aging.
• Treating Comorbid Bipolar Disorder and ADHD - Clinical Psychiatry News, 6/03
• Kodak devises a promising tool for diagnosing hyperactivity - USA Today, 5/23/03
• Adults Benefit From Drug Treatment for ADHD - Medscape, 5/22/03
• Bipolar Disorder Often Mistaken For ADHD In Kids - TheSanDiegoChannel.com, 5/7/03
• Psychopharmacology for ADHD in Adolescents: Quo Vadis? - Psychiatric Times, 5/03
• Children with Attention Deficit and Social Anxiety Disorder Show Major Deficits over kids with ADHD Alone - Doctor's Guide, 3/30/03
• Children With Eczema More Likely to Develop ADD - WebMD, 3/25/03
• Sleep Disorders Mimic ADHD Symptoms - WebMD, 3/3/03
• Sleep Deprivation in Normal Kids Leads To ADHD Symptoms - Clinical Psychiatry News, 3/03
• Behavior Training Helps ADHD Kids' Symptoms, Parents' Coping Skills - WebMD, 2/13/03
• Classes May Be Effective Treatment For ADHD Patients, Parents - Intelihealth, 2/13/03
• Stimulant Therapy In Attention Deficit Children Does Not Contribute To Later Drug Use - Doctor's Guide, 1/9/03
• ADHD Drugs Don't Lead to Drug Abuse - WebMD, 1/6/03
• 73% of Children Who Have ADHD Respond Favorably to Treatment With Stimulants - Clinical Psychiatry News, 12/02
• ADHD Kids May Have Bipolar Disorder, Too - WebMD, 10/29/02
• Screening for Comorbid Paediatric-Onset Bipolar Disorder Urged in Patients with Attention Deficit Hyperactivity Disorder - Doctor's Guide, 10/28/02
• Substance Use No More Likely in Adolescents with Attention Deficit/Hyperactivity Disorder Than Others with Psychiatric Disorders - Doctor's Guide, 10/28/02
• Donepezil (Aricept) May Improve Executive Functioning in ADHD - Doctor's Guide, 10/28/02
• Genetic, Early Influences On Brain Development Fixed In Attention Deficit Patients - Doctor's Guide, 10/9/02
• ADHD Kids Have Smaller Brains - WebMD, 10/8/02
• Attention Deficit Disorder May Plague More Girls Than Believed - Intelihealth, 10/2/02
• ADHD Is Often Overlooked in Girls - WebMD, 10/1/02
• Cephalon Announces Positive Results from a Study of Provigil (Modafinil) in Children with Attention Deficit Hyperactivity Disorder (ADHD) - Doctor's Guide, 9/17/02
• Optimizing ADHD Treatment - Psychiatric Times, 9/02
• ADHD--Overcoming the Specter of Overdiagnosis - Psychiatric Times, 8/02
• Surge in drugs given to kids draws concern - USA Today, 7/23/02
• Behavioral drugs should be researched first - USA Today, 7/14/02
• Hyperactivity Incidence Reports Depend On Criteria Used - Doctor's Guide, 3/18/02
• Mayo Clinic Studies Attention Deficit - Intelihealth, 3/14/02
• Child's View Of Anxiety Important In Attention Deficit Disorder - Doctor's Guide, 3/8/02
• Drug Guidelines Shift For Attention Deficit Disorder With Tics - Doctor's Guide, 3/6/02
• Study Links Snoring, ADHD - Intelihealth, 3/4/02
• Sleep and Behavioral Problems Linked - WebMD, 3/4/02
• Nonstimulants Important Alternatives, Adjuncts in ADHD - Clinical Psychiatry News, 3/02
• Risperidone Quells Disruptive Behavior in ADHD Patients - Clinical Psychiatry News, 3/02
• Learning Disorders Sink Some Kids With ADHD - Clinical Psychiatry News, 2/02
• Brief Questions Separate ADHD From Epilepsy - Clinical Psychiatry News, 2/02
• ADHD's Social Deficits Become Clear With Age - Clinical Psychiatry News, 12/01
• ADHD-Like Cognitive Deficits May Actually Be a Learning Disorder - Clinical Psychiatry News, 12/01
• Attention Deficit Plus Oppositional Defiant Disorder Increase Risk of Conduct Disorder - Doctor's Guide, 11/19/01
• New Guidelines Released for Managing Attention Deficit/Hyperactivity Disorder - Doctor's Guide, 10/24/01
• ADHD Meds May Worsen Adult-Onset Psychoses - Clinical Psychiatry News, 10/01
• Older Girls with Attention Deficit Hyperactivity Disorder Have More Depression, Anxiety - Doctor's Guide, 10/11/01
• New ADHD Drugs -- New Problems - WebMD, 9/7/01
• Addressing Pregnancy in Women on ADHD Medication - Clinical Psychiatry News, 9/01
• Sustained Release Bupropion May Aid Teen ADHD, Substance Abuse - Clinical Psychiatry News, 9/01
• Addressing Pregnancy in Women on ADHD Medication - Clinical Psychiatry News, 9/01
• Smarter Treatments Ahead for ADHD - WebMD, 8/24/01
• Paediatric Tic Disorders, Attention Deficit Hyperactivity Disorder Corrected With Guanfacine - Doctor's Guide, 8/7/01
• Pay Attention! - USA Today, 7/15/01
• How Ritalin Works in ADHD - WebMD, 7/12/01 - "the brains of children with ADHD have too little dopamine, a brain chemical needed for several vital brain functions. Why? It's because the children's brains have too many molecules that suck up dopamine before it does its thing. Ritalin gums up these molecules, so they leave the dopamine alone"
• Extended-Release Concerta (Methylphenidate) As Effective As Thrice Daily Doses For Attention Deficit Hyperactivity Disorder - Doctor's Guide, 6/5/01
• Ritalin (Methylphenidate)/Behaviour Therapy Combo Most Effective for Teens With Attention Deficit Hyperactivity Disorder - Doctor's Guide, 6/1/01
• Ritalin, Behavior Modification Make the Grade for ADHD, Teens With Disorder See Boost in Grades With Drugs, Guidance - WebMD, 5/31/01
• ADHD Treatment Can Stave Off Substance Abuse - Clinical Psychiatry News, 5/01
• ADHD: New Info, New Drug, Stimulants Don't Promote Substance Abuse, But If You Prefer, a New Nonstimulant in the Works - WebMD, 5/17/01 - "Early treatment of attention deficit hyperactivity disorder, or ADHD, with drugs is liable to protect kids from abusing substances later in life ... In related news at the meeting, researchers reported what appears to be successful treatment of ADHD using a nonstimulant drug called Atomoxetine"
• FDA Approves Metadate (Methylphenidate) Extended Release For Attention Deficit Hyperactivity Disorder - Doctor's Guide, 4/4/01 - "a once-daily biphasic formulation of methylphenidate"
• Study Raises Hopes For ADHD Medical Test - Intelihealth, 3/13/01
• Metronome said to help ADHD - CNN, 3/9/01 - "Not all ADHD specialists are convinced. They say the study was too small to draw conclusions and point out that children who used the metronome did little better than those who played video games instead ... The interactive metronome is available in 300 hospitals and clinics across the U.S., administered by therapists who have had 15 hours of training. It's not designed to replace existing therapies, but to complement them."
• Kids With ADHD Have Higher Healthcare Costs, But the ADHD May Not Be to Blame - WebMD, 1/2/01
• Attention Deficit Discovery - WebMD, 11/6/00 - ""When we gave these animals [Prozac], which affects the serotonin system, it had a dramatic effect on learning and memory, improving performance fourfold." Wetsel says."
• New ADHD Drug Rivals Ritalin's Effectiveness - WebMD, 10/26/00
• Kid's Behavior: Only as Good as Their Breakfast - WebMD, 9/21/00
• Survey: Attention-deficit disorder goes undiagnosed - CNN, 9/10/00
• FDA Approves ADHD Drug [Concerta] - Intelihealth, 8/2/00
• OROS Methylphenidate Reduces Attention Deficit Hyperactivity Disorder Symptoms - Doctor's Guide, 5/19/00
• Provigil (Modafinil) Reduced Attention Deficit/Hyperactivity Disorder Symptoms - Doctor's Guide, 5/18/00
• FDA Approves Extended Release Methylin (Methylphenidate) for Attention Deficit Hyperactivity Disorder - Doctor's Guide, 5/16/00
• Extended Release Concerta (Methylphenidate) As Effective as More Frequent Dosing - Doctor's Guide, 5/15/00
• Ritalin (Methylphenidate) and Prozac (Fluoxetine) Combined Frequently in Children - Doctor's Guide, 5/15/00
• Adderall (Amphetamine/Dextroamphetamine) Significantly More Effective Than Methylphenidate in ADHD - Doctor's Guide, 5/15/00
• Concerta (methylphenidate HCl) ER improves attention, behaviour in ADD/ADHD - Doctor's Guide, 5/5/00
• Professional group seeks consistency in diagnosing attention deficiency in children - CNN, 5/2/00
• Pediatrics Academy Issues ADHD Guide - Intelihealth, 5/2/00
• Bipolar Disorder Can Affect Young Children, May Co-Exist With ADHD - Doctor's Guide, 4/28/00
• Researchers Find Hyperactive Children Get Less Blood To Brain - Intelihealth, 3/29/00
• FDA Approves Metadate ER, New Extended-Release Drug For ADHD - Doctor's Guide, 12/6/99
• Single-Dose Of Adderall Lasts Entire School Day In Children With ADHD - Doctor's Guide, 12/6/99
• Busting the sugar-hyperactivity myth - CNN, 11/22/99
• Treat Depression First, Then AD/HD, Says Researcher - Doctor's Guide, 10/27/99
• AD/HD A Major Factor In Tic Disorder - Doctor's Guide, 10/27/99
• Bupropion SR Effective In Treating Adult AD/HD - Doctor's Guide, 10/26/99
• Guanfacine Effective For AD/HD And Tic Disorder - Doctor's Guide, 10/26/99
• Nicotine Patches Improve Adult AD/HD Symptoms - Doctor's Guide, 10/26/99
• Ritalin Has No Effect On Reading Disorders - Doctor's Guide, 10/26/99
• Deprenyl May Result In AD/HD Symptom Improvements - Doctor's Guide, 10/26/99
• Behavioral Intervention Decreases Need For Medication In AD/HD Children - Doctor's Guide, 10/26/99
• Adderall Offers Alternative To Ritalin - Doctor's Guide, 10/26/99
• Concerta May Provide Once-Daily Treatment For ADD/ADHD - Doctor's Guide, 10/25/99
• Attenade Offers Longer Duration Of Action Than Ritalin - Doctor's Guide, 10/25/99
• Tamoxetine Effective For AD/HD - Doctor's Guide, 10/25/99
• Attenade Effective In the Treatment Of ADD And ADHD - Doctor's Guide, 9/9/99
• Boys Treated With Stimulants Less Likely To Abuse Drugs As Adults - Doctor's Guide, 8/3/99
• Study Eases Hyperactivity Drug Worry - Intelihealth, 8/3/99
• Could your child have ADHD? - CNN, 7/9/99
• Once-Daily Adderall As Effective As Twice Daily For ADHD - Doctor's Guide, 6/29/99
• Once-Daily Adderall More Effective Than Ritalin For ADHD - Doctor's Guide, 5/19/99
• ADHD Treatments Effective In Patients With Sleeping Disorders - Doctor's Guide, 4/26/99
• Little Evidence Found Of Incorrect Diagnosis Or Overprescription For ADHD - Doctor's Guide, 4/7/98
• Improved Ritalin Offers Smaller Doses And Fewer Side Effects - Doctor's Guide, 3/23/99
• ADHD May Be Undertreated, Not Overtreated, Researcher Says - Doctor's Guide, 3/12/99
• Researchers learn how Ritalin works to calm hyperactivity - CNN, 1/15/99
• Smoking During Pregnancy Risk Factor For Attention Deficit Disorder - Doctor's Guide, 9/2/98
• Levodopa May Improve Attention Deficit Symptoms - Doctor's Guide, 4/30/98
• Findings Suggest Neuroanatomical Basis To ADHD - Doctor's Guide, 2/6/98