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Recent Longevity News for the seven days ending 1/15/03:

The Life Extension Foundation annual sale ends 1/31/03.  Logitec/Amazon.com have a $20 rebate on the Logitech QuickCam Pro 4000 until 1/31/03.  It comes to $69.99 delivered after rebate.  Yahoo wants $99.99 plus shipping for the same thing.  See Super Webcam.

A Better Way to Eat - Newsweek (cover story), 1/20/03 - "The Healthy Eating Pyramid has some controversial features, including a strong endorsement of calorie-rich vegetable oils and a virtual prohibition of potatoes and white rice. But its health effects have been cleverly evaluated and affirmed. The diet is designed not for short-term weight loss but for lifelong health ... a diet rich in refined carbs and simple sugars can erode that system. Cells become increasingly resistant to insulin, forcing the body to produce it in ever-greater amounts. Eventually the system breaks down, triggering diabetes and fostering heart disease ... Dairy products—which shoulder half of the USDA pyramid’s protein load—are optional in Willett’s pyramid, easily replaced by a calcium supplement"

How Your Mind Can Heal Your Body - Time Magazine, 1/20/03 - "More and more doctors—and patients—recognize that mental states and physical well-being are intimately connected. An unhealthy body can lead to an unhealthy mind, and an illness of the mind can trigger or worsen diseases in the body. Fixing a problem in one place, moreover, can often help the other ... Somehow depression makes the body less responsive to insulin, the hormone that processes blood sugar—plausibly through the action of cortisol, a hormone that can interfere with insulin sensitivity and that is often elevated in depressed patients ... Cortisol may also make depressed patients more prone to osteoporosis ... Cizza estimates that some 350,000 women get osteoporosis each year because of depression. Cortisol appears to interfere with the ability of the bones to absorb calcium and offset the natural calcium loss that comes with menopause and aging"

Bad Boy in the Blood: CRP - WebMD, 1/15/03 - "CRP doesn't just mark risk. It contributes to plaque formation in the blood-vessel wall. It promotes cholesterol uptake ... The most dazzling observation has been that in postmenopausal women, even those with low cholesterol levels, CRP identifies a three-fold increased risk for coronary artery disease ... When they added CRP to these cells, they saw dramatic effects. The cells began to secrete a substance called PAI-1. Increased PAI-1 secretion predicts formation of blood clots and heart disease. It also predicts diabetes and the pre-diabetes condition known as metabolic disorder ... You can lower your CRP levels by doing the same things you would do to lower your cholesterol levels: lose weight, eat fewer calories and a very low fat diet, take the cholesterol-lowering drugs known as statins, and the natural form of vitamin E"

Immune System May Sway Ovarian Cancer Survival - Yahoo, 1/15/03 - "among women with advanced ovarian cancer, those whose tumor samples contained T cells lived nearly three times longer than women whose tumors lacked the cells ... T cells help orchestrate the body's overall immune response, and can directly attack foreign, infected or cancerous cells ... The same association has already been found for several other cancers" - Ways to boost T cells?:

Tamoxifen Prevents Breast Cancer in Some - WebMD, 1/14/03 - "Tamoxifen reduced the risks for women with specific high-risk factors of developing the type of breast cancer that is estrogen-dependent (ER+). It was associated with an 82% reduction in risk ... One very important message is that every woman over 40 ought to discuss her level of risk with her physician ... And the 15% to 20% of women who are truly at increased risk should be referred for a formal risk assessment to determine if they are candidates for preventive therapy"

Intense Heart-Smart Program Pays Off - WebMD, 1/14/03 - "The healthy benefits of a low-fat diet, regular exercise, and cholesterol-lowering statin drugs may be much greater in combination than alone in helping people with heart disease prevent future heart attack, stroke, and even death. New research shows following a strict program that combines all three approaches can lower a person's chances of suffering a major heart-related problem from one in three to one in 15"

Exercise Alone Trims Tummy, Health Risks - WebMD, 1/14/03 - "173 sedentary, overweight menopausal women between the ages of 50 and 75 were randomly assigned ... Women in the exercise group participated in moderate exercise, such as brisk walking or riding a stationary bike for an average total of about 171 minutes a week ... After 12 months, researchers found that weight loss among the exercisers was modest, but the loss of intra-abdominal fat was considerable and increased with the amount of exercise. Women who exercised for more than 195 minutes a week lost almost 7% of intra-abdominal fat compared to a loss of about 4% among those who exercised between 136 to 195 minutes per week"

Depression tied to early menopause - MSNBC, 1/13/03 - "Women with a lifetime history of depression run a risk of entering the first stages of menopause years earlier than usual ... putting them at risk sooner in life for osteoporosis and other health problems ... it is possible depression itself has a direct impact on the production of hormones"

Depression Causes Brittle Bones - ABC News, 1/13/03 - "Cindy Uhl, a lab technician in Rochester, Minn., was one of those people determined to stay healthy. She exercised regularly, ate well, and routinely took vitamin and mineral supplements. Then one day two years ago, walking to work, she slipped and fell. Her wrist was shattered ... During the operation, doctors discovered why. Uhl had remarkably brittle bones. At only 46, she had advanced osteoporosis ... Cindy had the bones that were the equivalent of someone who's 15 to 20 years older than she was ... One likely explanation, doctors said, was that Uhl had suffered from a bout of depression years earlier".

C-Reactive Protein as a Predictor for Incident Diabetes Mellitus Among Middle-aged Men - Archives of Internal Medicine, 1/13/03 - "Low-grade systemic inflammation is associated with an increased risk of type 2 diabetes mellitus in middle-aged men. Inflammation could be one mechanism by which known risk factors for diabetes mellitus, such as obesity, smoking, and hypertension, promote the development of diabetes mellitus" - Inflammation has been associated with diabetes, arthritis, heart disease, Alzheimer's disease and stoke.  See my inflammation page for ways to reduce it.

Arthritis drug helps in heart disease - MSNBC, 1/13/03 - "Anti-inflammatory drugs used to treat arthritis may also reduce the risk of heart disease by keeping the arteries limber ... Their findings add to a growing body of research that suggests inflammation plays an important role in heart disease — perhaps as important as a fatty diet ... measured markers of heart disease, such as endothelial function — a measure of how efficiently blood vessels are working — levels of C-reactive protein, which is associated with both inflammation and heart disease, and levels of the fat that blocks arteries — oxidized low-density lipoprotein ... All three improved while the patients were on COX-2 inhibitors" [WebMD]

Ketoconazole Shampoo Superior In Treating Severe Dandruff, Seborrheic Dermatitis - Doctor's Guide, 1/13/03 - "Ketoconazole 2% shampoo is significantly better in treating severe dandruff or seborrheic dermatitis of the scalp than is zinc pyrithione 1% shampoo" - See Nizoral Shampoo at drugstore.comicon. Related article:

One electric toothbrush tops study - MSNBC, 1/12/03 - "Of five types of brushes examined, only the “rotational oscillation” design of the Braun Oral-B device was clearly more effective than manual toothbrushes ... Compared to manual brushes, that design removed about 11 percent more of the build-up on teeth known as plaque, and reduced by about 17 percent the development of gum disease, or gingivitis ... None of the other brushes evaluated — the Philips Sonicare, the Interplak, the Teledyne Aqua Tech, the Ultrasonex, the Rowenta Dentiphant and the Rowenta Plaque Dentacontrol Plus — performed better than manual brushes" - See Drugstore.com Braun Oral-B productsicon.

Calcium benefits more than bones - MSNBC, 1/10/03 - "Research from the University of Tennessee, published in the Journal of the American College of Nutrition and elsewhere, suggests that greater dietary calcium makes cells less likely to store fat and more likely to burn fat when calorie intake is reduced. In a complex chain of events, too little calcium in the diet brings cell changes that lead to decreased fat-burning and increased fat storage ... In two large studies reported in the Journal of the National Cancer Institute, people with higher calcium consumption developed 35 percent fewer cases of a certain type of colon cancer than people with low-calcium diets ... pre-menopausal women with higher calcium consumption developed about 30 percent less breast cancer than those who consumed very little. Another study suggests that calcium may offer some protection against ovarian cancer ... In studies of cancer risk, calcium was protective at levels of 700 to 900 mg a day. Studies of weight control found benefits from 1,000 to 1,500 mg daily" - The problem with taking calcium supplements that articles like this never cover is that calcium interferes with magnesium, zinc and copper absorption and zinc interferes with magnesium and copper absorption.  You should take a supplement that has these in the proper rations like Body Wise Essential Calcium.  See:

Coenzyme Q10 Improves High Blood Pressure - New Hope Natural Media, 1/9/03 - "recruited 83 people with a condition called isolated systolic hypertension (ISH), in which the higher blood pressure ... These people were assigned to take either 60 mg of CoQ10 twice daily or a placebo for 12 weeks ... The people taking CoQ10 had an 18-point (18 mm Hg) reduction in systolic blood pressure (from 165 to 147 mm Hg), compared with only a 2-point decline in the placebo group ... ISH is the most common type of high blood pressure in the United States" - See iHerb (5% discount code "qc") and Vitacosticon coenzyme Q10 products.

Mystery of Viagra Deaths Unravels - WebMD, 1/9/03 - "the drug may actually encourage potentially dangerous blood clots to form in men with certain risk factors, such as hardening of the arteries"

Folic acid intake tied to colon cancer risk - Reuters, 1/9/03 - "the incidence of the disease was 40% higher for patients who were heavy drinkers and had diets deficient in folate and the essential amino acid methionine"

Vitamins C and E Improve Outcome in Critically Ill Surgical Patients - New Hope Natural Media, 1/9/03 - "Five-hundred and ninety-five people admitted to a surgical intensive care unit (ICU), 91% of whom were victims of trauma, were randomly assigned to receive standard care (control group) or standard care plus vitamins C and E. Vitamin E was given orally in the amount of 1,000 IU three times per day, and vitamin C was given intravenously in the amount of 1,000 mg three times per day ... The incidence of multiple organ failure was significantly lower (by 57%) in the group receiving antioxidants than in the control group (2.7% vs. 6.1%). In addition, the average length of stay in the ICU was significantly lower (by 17%) in the antioxidant group.  After 28 days, the mortality rate was 44% lower in the antioxidant group than in the control group (1.3% vs. 2.4%), but this difference was not statistically significant" - Click here for the Medscape article on same study.

More Booze, Fewer Heart Attacks? - WebMD, 1/8/02 - "men who drank alcohol three to four times or more per week were about 30-40% less likely to have a heart attack during the 12-year period, compared with men who drank less than once a week ... the type of alcohol beverage didn't matter -- beer, wine, or liquor -- they all provided some protection against heart disease, although the strongest association for the reduced risk was with beer and liquor"

Policosanol Improves Lipid Profiles - Natural Foods Merchandiser, 1/03 - "In one eight-week study with 68 older patients who had both elevated LDL levels and various coronary heart disease risk factors, researchers found 10 mg of Cuban policosanol taken once daily reduced (from baseline) LDL levels by 19 percent and triglycerides by 14 percent, and increased HDL levels by 18 percent, all statistically significant changes.26 The statin group (10 mg per day of pravastatin, the lowest dose recommended) triggered a 16 percent reduction in LDL levels, no change in triglycerides, and a 6 percent increase in HDL levels" - See iHerb (5% discount code "qc") and Vitacost policosanol productsicon policosanol products.

The Anti-Aging Effects of Carnosine - Life Extension Magazine, 1/03 - "Carnosine quenches the most destructive protein-oxidizing agent (the hydroxyl radical). One study showed carnosine was the only antioxidant to significantly protect cellular chromosomes from oxidative damage.2 Antioxidants cannot completely protect proteins. Nature's second line of defense is to repair or remove damaged proteins.3 This is where carnosine demonstrates its most profound anti-aging effect ... Studies show that carnosine is effective against cross-linking and the formation of advanced glycation end products (AGE).6,7 Glycated proteins produce 50-fold more free radicals than nonglycated proteins and carnosine may be the most effective anti-glycating agent known" - See iHerb (5% discount code "qc") and Vitacosticon carnosine products.

Affiliates (I could sure use some sales.  Click here for more stores):

Life Extension Foundation / iHerb - use this link to receive a 5% discount (discount code "qc") plus free shipping on orders over $60 / Vitacost.com / VitaminShoppe / Gerovital / Free Shipping at drugstore.com / GNC / Bare Necessities (everyone needs underwear) / Body Wise International / DiabetesStore.Com (syringes for hGH) / Gero Vita International / DermaDoctor / Dr. Whitaker / Online Prescriptions / Body by Jake / Love Scents Pheromones / Mass Quantities / Netrition.com / Road Runner Sports / Amazon.com / Office Depot / The Sports Authority / J & R Appliance Store / Dell Computer / Buy.com / Lands' End / Walmart / Tupperware / REI / Verizon Wireless!

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iHerb policosanol products - use this link to receive a 5% discount (discount code "qc") plus free shipping on orders over $60 - see policosanol

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