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Anti-aging Research > Astragalus (Astragalus membranaceus)
Astragalus (Astragalus membranaceus)
Specific Recommendations:
News & Research:
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Astragalus (Astragalus membranaceus) - Delicious Living, 10/05
- The Herbal Way
To Keep Flu at Bay - WebMD, 12/12/03 -
"Astragalus is an immune-enhancing herb to ward off flu," Weil says""
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Astragalus Asserts Immunity - Nutrition Science News, 10/00
-
Herbal Aids for Cancer - Nutrition Science News, 3/00
-
Immune Enhancers - Nutrition Science News, 2/99
Abstracts:
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Protective Effect of a
Mixture of Astragalus membranaceus and Lithospermum erythrorhizon Extract
against Hepatic Steatosis in High Fat Diet-Induced Nonalcoholic Fatty Liver
Disease Mice - Evid Based Complement Alternat Med. 2020 Mar 19 -
"The present study aimed to evaluate the potential
synergistic and protective effects of ALM16, a mixture of Astragalus
membranaceus (AM) and Lithospermum erythrorhizon (LE) extract in a ratio of
7 : 3, against hepatic steatosis in high fat diet (HFD)-induced nonalcoholic
fatty liver disease (NAFLD) mice. Forty-eight mice were randomly divided
into eight groups and orally administered daily for 6 weeks with a normal
diet (ND) or high fat diet alone (HFD), HFD with AM (HFD + 100 mg/kg AM
extract), HFD with LE (HFD + 100 mg/kg LE extract), HFD with ALM16
(HFD + 50, 100, and 200 mg/kg ALM16), or HFD with MT (HFD + 100 mg/kg Milk
thistle extract) as a positive control. ALM16 significantly decreased the
body and liver weight, serum and hepatic lipid profiles, including
triglyceride (TG), total cholesterol (TC), high-density
lipoprotein-cholesterol (HDL), and low-density lipoprotein-cholesterol
(LDL), and serum glucose levels, compared to the HFD group. Moreover, ALM16
significantly ameliorated the HFD-induced increased hepatic injury markers,
including aspartate aminotransferase (AST), alanine aminotransferase (ALT),
alkaline phosphatase (ALP), lactate dehydrogenase (LDH), and gamma-glutamyltransferase
(GGT)-1. Furthermore, as compared to the mice fed HFD alone, ALM16 increased
the levels of phosphorylated AMP-activated protein kinase (p-AMPK) and
acetyl-CoA carboxylase (p-ACC), thereby upregulating the expression of
carnitine palmitoyltransferase (CPT)-1 and downregulating the expression of
sterol regulatory element-binding protein (SREBP)-1c and fatty acid synthase
(FAS)" - See Astragalus at
Amazon.com and Lithospermum
erythrorhizon at Amazon.com.
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