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Health Conditions > Lupus
Lupus
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Alternative News:
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Quercetin Ameliorates Renal
Injury and Pyroptosis in Lupus Nephritis through Inhibiting IL-33/ST2 Pathway In
Vitro and In Vivo - Antioxidants (Basel) 2022 Nov 1 -
"Lupus nephritis (LN) is a common and serious symptom in
patients with systemic lupus erythematosus (SLE). Tubular interstitial fibrosis
is a common underlying mechanism in the development of lupus nephritis to
end-stage renal failure (ESRD). Quercetin is widely proven to prevent tissue
fibrosis ... The in vivo results showed that quercetin improved the renal
function and inhibited both fibrosis- and inflammation-related markers in MRL/lpr
mice animal models. The in vitro results indicated that quercetin ameliorated
the accumulation of fibrosis- and inflammation-related proteins in IL-33-induced
HK-2 cells and improved renal cell pyroptosis via the IL33/ST2 pathway. Overall,
quercetin can improve LN-related renal fibrosis and inflammation, which may
offer an effective potential therapeutic strategy for lupus nephritis" -
See quercetin at Amazon.com.
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Effects of Melatonin
Supplementation on Serum Oxidative Stress Markers and Disease Activity in
Systemic Lupus Erythematosus Patients: A Randomized, Double-Blind,
Placebo-Controlled Trial - Int J Clin Pract 2021 Apr 20 -
"This study demonstrated affirmative effects of
melatonin in decreasing oxidative stress in SLE patients without any effect on
disease activity" - See melatonin at Amazon.com.
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Vitamin D supplements may benefit lupus patients - Science Daily,
10/17/12
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Beneficial Effects of Taurine on Cardiac Abnormality in NZB/W F1 Mice Fed
with a High-Cholesterol Diet J Agric Food Chem. 2009 Aug 14 -
"Improved cardiac histopathological changes were
observed in left ventricle tissues from the cholesterol/taurine group as
compared to the control or cholesterol group. Significant reductions of
TUNEL-positive cells, Fas death receptor-related components,
mitochondrial-dependent apoptosis, cardiac fibrosis, and fibrotic signaling
components were detected in the left ventricle tissues from the
cholesterol/taurine group as compared to the control or cholesterol group.
Additionally, cardiac IGR1R survival signaling components were significantly
increased in the left ventricle tissues from the cholesterol/taurine group
as compared to the control or cholesterol group. These findings revealed the
protective effects of taurine against the cardiac abnormalities in NZB/W F1
mice and may suggest the potential for clinical application of taurine in
treatment of CVD in SLE" - See
taurine at Amazon.com
 .
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Omega-3 Fish Oil Improves Lupus Symptoms, Shows Possible Cardiovascular
Benefits - Doctor's Guide, 11/12/07 - "They
received 3 grams of omega-3 fish oils, daily, for 24 weeks ... Low dose
dietary supplementation with omega-3 fish oils in SLE not only has a
therapeutic effect on disease activity but also improves endothelial
function and reduces oxidative stress and may, therefore, confer
cardiovascular benefits" - See Mega Twin EPA at Amazon.com.
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Fish Oil Supplements May Ease Lupus - WebMD, 11/7/07 -
"Fish oil supplements may help improve the symptoms
of lupus ... the supplements also improve blood flow and blood vessel
function in people with lupus who are known to be at increased risk for
heart disease" - See Mega Twin EPA at Amazon.com.
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A randomised placebo-controlled interventional trial of
omega-3-polyunsaturated fatty acids on endothelial function and disease
activity in systemic lupus erythematosus - Ann Rheum Dis. 2007 Sep 17 -
"Low dose dietary supplementation with omega-3 fish
oils in SLE not only has a therapeutic effect on disease activity but also
improves endothelial function and reduces oxidative stress and may therefore
confer cardiovascular benefits"
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Exercise Cuts
Fatigue of Lupus, MS - WebMD, 11/30/06
- Fish Oil Helpful for
People with Lupus - Healthwell.com, 9/23/04
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'Antiaging' Hormone Helps Women With Lupus - WebMD, 9/9/04
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The Clinical Effect of Dietary Supplementation with Omega-3 Fish Oils and/or
Copper in Systemic Lupus Erythematosus - J Rheumatol. 2004
Aug;31(8):1551-6 - "There was a significant decline
in SLAM-R score from 6.12 to 4.69 (p < 0.05) in those subjects taking fish
oil compared to placebo" - See Mega Twin EPA at Amazon.com
or
Vitacost
 .
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DHEA Supplementation Linked to Improved Quality of Life in Women with
Systemic Lupus Erythematosus - Doctor's Guide, 6/15/04 -
"Their partners reported greater responses to the "gets more done" question
compared to placebo ... DHEA replacement decreased high-density lipid (HDL)
cholesterol, and it increased insulin-like growth factor (IGF-I) and
haematocrit"
- DHEA Improves Quality
of Life in Women With SLE - Medscape, 6/14/04
- Can Broccoli
Prevent Lupus? - WebMD, 11/6/03 -
"I3C is believed to act as
an anti-estrogen ... At 12 months of age, 80% of the mice fed the I3C diet
from soon after birth were alive, compared with only 10% of the
non-supplemented mice. Normal mice live from one to two years ... I3C-fed
mice had far fewer kidney problems than the mice whose diets were not
supplemented, and researchers say this is the reason that they lived much
longer. Kidney disease is one of the main, life-threatening complications of
lupus" - See
indole-3-carbinol at Amazon.com.
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Dehydroepiandrosterone Reduces Flares in Mild-to-Moderate Systemic Lupus
Erythematosus - Doctor's Guide, 12/6/02
- Lupus: A Natural Approach?
- Dr. Weil, 6/26/02
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Health Supplement [DHEA] A Hit Among Lupus Sufferers
- Intelihealth, 8/13/01
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Studies Show DHEA Quells Lupus - Nutrition Science News, 10/00
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Could Drug Containing DHEA Be an Answer for Lupus? - WebMD, 6/23/00
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Dipping DHEA Levels May Trigger Lupus - Nutrition Science News, 1/99
CME:
General Information:
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Lupus - American Academy of Family Physicians
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Lupus - emedicine.com
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Lupus - FamilyDoctor.org
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Lupus - Intelihealth
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Lupus Basics - Medscape
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Lupus - Veritas Medicine
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Treatments for lupus
- Medifocus.com
Other News:
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New Drug May Reduce Severity of Lupus - WebMD, 10/20/09
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Insecticides May Raise Risk of Lupus, RA - WebMD, 10/20/09
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Lupus May Lessen Sense of Smell - WebMD, 5/7/09
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Lupus Kidney Damage Linked To Malfunction Of Immune Cells - Science
Daily, 4/21/09
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Alternative Therapy For Lupus Nephritis - Science Daily, 4/15/09
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Birth Control Pills May Raise Lupus Risk - WebMD, 4/13/09
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Lupus More Severe In Patients With Southern European Ancestry - Science
Daily, 6/11/08
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Existing Drugs Show Promise For Treating End-stage Renal Disease In Lupus
- Science Daily, 11/27/07
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New
Way To Detect Lupus-associated Kidney Disease - Science Daily, 11/25/07
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Mycophenolate Mofetil Reduces Lupus Flares and Cuts Prednisone Use -
Doctor's Guide, 11/13/07
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New
Way To Detect Lupus-associated Kidney Disease - Science Daily, 11/13/07
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Targeted Treatment Strategies For Lupus Suggested By Research - Science
Daily, 11/11/07
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Existing Drugs Show Promise For Treating End-stage Renal Disease In Lupus
- Science Daily, 11/9/07
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Therapy Effective For Reducing Lupus Flares, Study Suggests - Science
Daily, 11/9/07
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New Vaccine May Treat Lupus - WebMD, 10/1/07
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Men's Lupus Treatment Linked to Fertility Woes - WebMD, 6/28/07
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Belimumab Improved Symptoms in Almost Half of Lupus Patients - Doctor's
Guide, 6/20/07
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Spleen May Be Target Of Successful Therapy For Lupus - Science Daily,
9/15/06
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Anti-Malarials Most Effective in Lupus Patients Genetically at Risk of High
Levels of TNF-Alpha - Doctor's Guide, 2/13/06
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Stem Cells May Ease Severe Lupus - WebMD, 1/31/06
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Stress Hormone Enables Lupus Antibodies to Alter Behavior, Damage Cognition
- Doctor's Guide, 1/24/06
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Study Demonstrates Safety of Oral Contraceptives in Women with Lupus -
Doctor's Guide, 12/22/05
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Research Published in The New England Journal of Medicine Challenges
30-Year- Old Standard of Care for Lupus Patients - Doctor's Guide,
11/24/05
- Drug helps treat kidney
issues in lupus patients - MSNBC, 11/23/05
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Patients with Lupus Living Longer, Aggressive Use of Immunosuppressants May
Be the Reason - Doctor's Guide, 11/21/05
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Drug
May Fight Lupus And Atherosclerosis Simultaneously - Science Daily,
11/21/05
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Common Anti-seizure Drug Could Be Effective For Lupus Patients - Science
Daily, 11/21/05
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Lipstick, Hair Dyes Raise Lupus Risk? - WebMD, 11/17/05
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Lupus Survival Getting Better - WebMD, 11/16/05
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Study Uncovers Potential Biomarker For Lupus Atherosclerosis - Doctor's
Guide, 11/16/05
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Genelabs Receives Confirmation of Orphan Drug Designation for Prestara
(Prasterone) and Provides Update on Its Development - Doctor's Guide,
6/23/05
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A
Candidate Biomarker To Improve Treatment Of Lupus Patients - Science
Daily, 5/8/05
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Lupus And The Role Of Epstein-Barr Virus - Science Daily, 4/16/05
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Lupus And The Role Of Epstein-Barr Virus - Doctor's Guide, 4/7/05
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Pitt Researchers Identify Biomarkers Of Lupus Which Could Lead To Quicker
And Better Diagnosis - Science Daily, 11/9/04
- Organ
Transplant Drug Controls Lupus Symptoms - WebMD, 10/18/04
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Cancer Drug Shows Promise Against Lupus - Science Daily, 9/16/04
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Prasterone Therapy Appears to Benefit Women With Lupus
- Doctor's Guide, 9/9/04
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Mycophenolate Mofetil May Be as Effective as Cyclophosphamide in Treating
Paediatric Lupus - Doctor's Guide, 5/3/04
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Patients With Lupus At High Risk of Urinary Tract Infections
- Doctor's Guide, 4/12/04
- Cigarette
Smoking Increases Lupus Risk - WebMD, 3/4/04
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Mycophenolate Mofetil Appears Safe, Effective for Lupus Nephritis
- Doctor's Guide, 1/27/04
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Early and Frequent Development of Atherosclerosis in Patients with Systemic
Lupus Erythematosus Appears Disease Related - Doctor's Guide, 12/19/03
- Lupus Patients
Risk Early Heart Disease - WebMD, 12/17/03
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Simple Blood Test Effective for Diagnosing Lupus - Physician's Weekly,
11/24/03
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Mycophenolate Mofetil Equivalent to Cyclophosphamide for Treatment of Lupus
Nephritis - Doctor's Guide, 11/18/03
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Cumulative Prednisone Dose Among Important Risk Factors Identified For
Atherosclerosis in Systemic Lupus Erythematosus Patients
- Doctor's Guide, 11/12/03
- More Heart
Disease Risks With Lupus - WebMD, 11/10/03
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Treatment with Mycophenolate Mofetil May Become First Line of Therapy for
Lupus Nephritis - Doctor's Guide, 11/4/03
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Mycophenolate Mofetil (CellCept) Tops Standard Intravenous Cyclophosphamide
for Severe Lupus - Doctor's Guide, 10/30/03
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Patients With Systemic Lupus Erythematosus More Likely to Have Increased
Prolactin Levels - Doctor's Guide, 10/23/03
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Systemic Lupus Erythematosus Autoantibodies Progressively Develop While
Patients Are Asymptomatic - Doctor's Guide, 10/20/03
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Statins may play a role in the treatment of inflammatory rheumatic diseases
- Doctor's Guide, 9/28/03 - "the administration of
simvastatin for 8 days was associated with a rapid and significant reduction
in proteinuria levels in the three patients with SLE, as well as in the 2
patients with systemic vasculitis. In the five patients with
RA, atorvastatin for 8 days was associated with a reduction in
C-reactive protein levels and clinical improvement ... statins may have
an important therapeutic potential for different inflammatory diseases"
- Note: Red yeast rice is a non-prescription
statin but check with your doctor. See
iHerb
or
Vitacost
red yeast rice products.
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Renal Disease in Systemic Lupus Erythematosus: a Review
- Doctor's Guide, 9/22/03
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Common Link Suggested Between Non-Hodgkin's Lymphoma, Lupus, and
Epstein-Barr Virus - Doctor's Guide, 8/12/03
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Mycophenolate Mofetil Effective, Tolerable in Patients with Systemic Lupus
Erythematosus - Doctor's Guide, 8/6/03
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Improved Survival in Systemic Lupus Erythematosus Associated with Changes in
Mortality Patterns - Doctor's Guide, 6/20/03
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Immunosuppression for Lupus Nephritis Safely Modified in Tropical Climate
- Doctor's Guide, 6/16/03
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Anti-Chromatin Antibodies Marker For Systemic Lupus Erythematosus
Nephropathy - Doctor's Guide, 5/2/03
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Adverse Drug Reactions to Sulfa Antibiotics in Patients with Systemic Lupus
Erythematosus than in Those with Other Inflammatory Arthritic Diseases
- Doctor's Guide, 4/17/03
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Antibodies Not Linked to Organ Damage in Systemic Lupus Erythematosus
- Doctor's Guide, 3/13/03
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Low-Dose Thalidomide Combats Refractory Lupus - Doctor's Guide, 2/18/03
- Drug
[Trichostatin A] Helps Fight Lupus Kidney Problems
- WebMD, 2/18/03
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Cyclophosphamide Cancer Therapy May Offer Lupus Patients New Hope
- Doctor's Guide, 1/10/03
- High-Dose
Cyclophosphamide Promising in Refractory Lupus
- Medscape, 1/8/03
- Lupus Hope:
No-Transplant Chemotherapy - WebMD, 1/6/03
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Diet Programme Comprehensively Benefits Lupus Patients
- Doctor's Guide, 11/7/02
- Rituximab Improves
Symptoms in Patients With SLE - Medscape, 10/29/02
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Angiotensin II Receptor Blockers Reduce Proteinuria In Lupus Nephritis
- Doctor's Guide, 10/29/02
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Cancer Drug Rituximab Benefits Patients With Systemic Lupus Erythematosus
- Doctor's Guide, 10/28/02
- Compound Holds
Promise for Lupus - WebMD, 10/16/02
- Cancer Drug
[Rituxan] Shows Promise in Lupus - WebMD, 10/4/02
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Intravenous Cyclophosphamide Has Marked Impact In Child Lupus Nephritis
- Doctor's Guide, 9/25/02
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Cyclophosphamide Effective in Children with Lupus Nephritis
- Doctor's Guide, 9/9/02
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Watson Notified of Approvable Letter for Aslera (GL701)
- Doctor's Guide, 8/30/02
- Environmental
Reason for Lupus? - WebMD, 8/5/02
- Stem Cells Save
Another Lupus Patient - WebMD, 6/5/02
- Deaths From Lupus
on the Rise - WebMD, 5/2/02
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Total Lymphoid Irradiation An Option For Unresponsive Severe Lupus Nephritis
- Doctor's Guide, 4/15/02
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Improving Aerobic Fitness in Systemic Lupus Erythematosus
- Doctor's Guide, 3/12/02
- Living With Lupus
- WebMD, 3/6/02
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Clue Suggested For Inflammation In Lupus Patients
- Doctor's Guide, 2/4/02
- LJP 394 Improves/Sustains
Health-Related Quality of Life in Lupus Renal Disease
- Doctor's Guide, 1/10/02
- LJP 394 as Effective as
Current Immunosuppressive Therapy for Renal Disease in Lupus
- Doctor's Guide, 11/14/01
- Finding May
Explain Why Lupus Affects the Brain - WebMD, 11/1/01
- Aslera (GL701 Or
Prasterone) Reduces Lupus Disease Activity And Symptoms
- Doctor's Guide, 10/31/00
- LJP 394 Reduces Renal
Flares In Lupus Patients With Poor Renal Function
- Doctor's Guide, 10/31/01
- LJP 394 Shows Promise in
Lupus Nephritis - Doctor's Guide, 10/16/01
- Alendronate Used To Treat
Some Pediatric Bone Mineral Loss - Doctor's Guide, 9/25/00
-
Cure for Lupus May Be in Sight, Stem Cell Transplant Also May Help Similar
Diseases - WebMD, 8/25/00
- New Diagnostic Test For
Lupus To Bridge Detection Gap
- Doctor's Guide, 8/8/00
-
Enzyme Blamed As Cause Of Lupus - Intelihealth, 5/31/00
- LJP 394 shows encouraging
results in lupus patients - Doctor's Guide, 5/3/00
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Lupus-Associated Antibodies Reduced With Toleragen - Doctor's Guide,
2/16/00
- Chemo Drug Effective For
Autoimmune Disorders Such As Rheumatoid Arthritis, Lupus
- Doctor's Guide, 12/15/98
-
Researchers look to stop bone loss in lupus patients - CNN, 10/13/98
- Researchers Find New
Pathway For Kidney Disease In Lupus - Doctor's Guide, 2/16/98
- Misunderstanding About
Lupus Puts Young People At Risk
- Doctor's Guide, 12/29/97
- Common Virus May Be Linked
To Lupus - Doctor's Guide, 12/16/97
- Discovery Of Protein
Fragments May Lead to Cure, Prevention Of Lupus
- Doctor's Guide, 6/2/97
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