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Recent Longevity News for the seven days ending 7/23/03:
Study Supports Potential of Nonsteroidal Anti-inflammatory Drugs to Protect
Against Alzheimer's - Doctor's Guide, 7/22/03 -
"The pooled combined data from the cohort and case-control studies showed a
relative risk of Alzheimer's disease was 0.72
among NSAID users ... The analysis specific to
aspirin users included eight studies that showed a pooled relative risk of 0.87
for developing Alzheimer's disease" - See
drugstore.com ibuprofen products Low-Cholesterol Diet as Good as Drugs - WebMD, 7/22/03 - "a vegetarian diet combining four types of cholesterol-lowering foods works as well as cholesterol-lowering drugs known as statins ... It had four basic components: plant sterols in the form of a cholesterol-lowering margarine; soy proteins; sticky or soluble fibers such as fruits, vegetables, oats, and legumes; and almonds" - If you look at their sample menu, it contained a lot of psyllium. That alone could have been responsible for a lot of the drop in cholesterol. See:
A Tomato a Day Keeps Heart Disease Away - HealthDay, 7/21/03 - "reviewed the diets of approximately 40,000 women from the ongoing Women's Health Study, which was begun 11 years ago to follow women who, at the time, were free from cancer and cardiovascular disease ... women who consumed seven or more servings of tomato-based foods a week -- including tomato juice, tomatoes, tomato sauce or pizza -- had a nearly 30 percent reduction in risk for cardiovascular disease" - See Lycosorb (with Lyc-O-Mato™) at iHerb. Pizza Prevents Cancer? It's Part of the Mediterranean Diet - WebMD, 7/21/03 - "Gallus and colleagues sifted through diet surveys completed by 5,500 Italians ... regular pizza eaters had 34% less risk of oral cavity and pharyngeal cancer, 59% less risk of esophageal cancer, and 25% less risk of colon cancer ... Italian pizza is less than 50% crust, 20% tomato sauce, 20% mozzarella cheese, and 4% olive oil ... There's less refined carbohydrates, plus cooked tomatoes, which are a rich source of lycopene, a natural chemical that has been shown in numerous studies to protect against cancer ... We think that there's a specific compound in cooked tomatoes that is protective" Osteoporosis Linked to Joint Destruction in Postmenopausal Rheumatoid Arthritis - Doctor's Guide, 7/21/03 - "Up to 56% of postmenopausal women with rheumatoid arthritis (RA) who are not treated with hormone replacement therapy (HRT) or bisphosphonates develop osteoporosis" Raloxifene Increases Bone Mineral Density and Decreases Osteoporosis Incidence Over 5 Years - Doctor's Guide, 7/21/03 - "Compared with placebo, raloxifene treatment significantly reduced values of bone turnover markers, including osteocalcin, bone-specific alkaline phosphatase, and urinary C-telopeptide. In addition, raloxifene treatment was associated with 2.8% increase in BMD in the lumbar spine (P<0.001) and a 2.6% increase in total hip BMD ... Incidence of hot flashes was higher among women taking raloxifene"
Fish Once a Week Cuts Alzheimer's Risk - WebMD,
7/21/03 - "Weekly
fish eaters had a 60% lower risk of
Alzheimer's than people who rarely or never ate fish ... The beneficial
effects of [fatty acids] from fish may be counterbalanced by toxins ... A high
antioxidant/low saturated fat diet pattern with a greater amount of fish,
chicken, fruits, and vegetables and less red meat and dairy products is likely
to lower the risk of AD, as well as that for heart disease and stroke ...
Furthermore, B vitamin supplements, containing vitamins B12 and B6 and folic
acid, lower plasma total homocysteine levels, possibly decreasing the risk of
stroke, heart disease and perhaps Alzheimer's disease" [USA
Today] - See Mega Twin EPA at
Vitacost Cholesterol Ratio More Indicative Than LDL - Physician's Weekly, 7/21/03 - "the ratio of LDL and HDL cholesterol may be better for identifying the risk of heart disease compared to relying solely on the individual levels of each kind of cholesterol. The study found that the ratio of LDL to HDL cholesterol and the ratio of total cholesterol to HDL cholesterol can better predict the risk of heart disease rather than measuring LDL levels alone. LDL/HDL ratios may more effective at identifying high-risk individuals and tracking their progress on cholesterol-lowering drugs. The researchers noted that despite newer recommendations incorporating HDL into risk assessment, LDL continues to be the major target of cholesterol-lowering therapy ... Certain low-fat diets that reduce both LDL and HDL levels may be less beneficial than diets that boost HDL cholesterol levels. Losing weight, quitting smoking, and exercising more often can increase HDL cholesterol" Lower cholesterol for healthy kidneys - USA Today, 7/20/03 - "men who had low levels of HDL or "good cholesterol" and elevated "bad" or LDL cholesterol were twice as likely to have evidence of kidney malfunction" Low "Good" Cholesterol Predicts Death in Elderly - Medline Plus, 7/18/03 - "measured cholesterol levels in 561 subjects who had recently reached 85 years of age. The subjects were then followed for 4 years ... Levels of LDL, the "bad" type of cholesterol, did not influence the risk of death from cardiovascular disease ... Subjects with HDL cholesterol levels below 40 mg/dL were twice as likely to die from stroke or heart disease than were subjects with levels above 46 mg/dL ... Low levels of HDL as well as LDL cholesterol more than doubled the risk of death from infection" - See my HDL page for possible ways to raise it. Depression Most Costly Illness for Employers - Psychiatric News, 7/18/03 - "workers with depression cost employers more than three times the amount associated with lost productivity from all other illness ... Twenty percent of the $44 billion cost of depression was accounted for by absenteeism, while 80 percent of the costs associated with depression, or $35.7 billion, was linked to "presenteeism"—that is, present on the job but with significantly reduced productivity"
Vitamin D and Calcium Supplementation Effective for Prevention and Treatment of
Osteoporosis - Doctor's Guide, 7/18/03 -
"Adequate
vitamin D and
calcium intake is essential to the prevention and treatment of
osteoporosis. The Institute of Medicine (IOM) recommends 200 IU/day of
vitamin D for women aged 50 or younger years, 400 IU/day for those aged 51-70
years, and 600 IU/day for those older than 70 years ... In women over the age of
65, there is increased risk of
osteoporotic fracture of the hip
and non-vertebral sites. Daily vitamin D intake between 800 and 900 IU and
1200-1300 mg of calcium for this population results in increased bone density,
decreased bone turnover, and decreased non-vertebral fractures ... Studies have
linked vitamin D supplementation to a decrease in body sway, suggesting that
vitamin D supplementation may protect against fracture by preventing falls"
- See
drugstore.com/GNC calcium plus vitamin D supplements
Keep Up Your Calcium - ABC News, 7/17/03 -
"A high calcium intake may also helps you lose weight if you're on a weight
reduction regimen. Low calcium intakes force the body to secrete hormones that
help conserve calcium. Some of the effects of these hormones cause the body's
fat cells to go into storage mode. As a result, during dieting a low calcium
intake tells the cells to hang onto the fat they have and try to get more"
- See
drugstore.com/GNC calcium supplements Ritalin Seen as Possible Aid to Seniors - Medline Plus, 7/17/03 - "in older people, Ritalin helps them get up and moving. Most doctors though are wary of the drug because of potential side effects such as loss of appetite, elevated blood pressure and increased heart rates ... The Journal cited the case of Edie Dominquez, a 62-year-old liver-transplant patient, exhausted and dejected following his operation, feeling "like garbage." But, a generic form of Ritalin soon had him more responsive, talkative and eating better" High-Fat Diet, Breast Cancer Linked - CBS News, 7/17/03 - "those who average more than 90 grams of fat a day have roughly double the risk of those who eat just 37 grams" - That's another area that hasn't been fully researched regarding the Atkin's diet. Related article:
Glucosamine Has Structural/Symptomatic Efficacy while Chondroitin Has
Symptomatic Efficacy in Knee Osteoarthritis - Doctor's
Guide, 7/17/03 - "Glucosamine
has structural efficacy and both glucosamine and
chondroitin have indistinguishable symptomatic efficacies in knee
osteoarthritis" [WebMD]
- See
iHerb or
Vitacost Studies Associate Fish And Multivitamins With Reduced Risk For Colorectal Cancer - Doctor's Guide, 7/16/03 - "Only fish consumption was associated with a reduction in risk ... Both processed meat and red meat consumption were associated with increased risk ... Duration of multivitamin use was associated with a decreased risk of rectal cancer" Herbalife International Introduces Niteworks(TM) to Boost Production of Nitric Oxide to Promote Cardiovascular Health - NPI Center, 7/8/03 - "The amino acid complex includes: L-arginine, which is transported into endothelial cells to produce NO, and L-citrulline, which is transported by a different mechanism and then is recycled into L-arginine, creating more NO. This different mechanism is important because when the L-arginine transporter sees too much L-arginine, it stops absorbing, so less L-arginine in the systems means less NO production" - See iHerb l-citrulline products. Innovative New Form of Folate Supplementation - NPI Center, 6/26/03 - "recent studies have shown that as many as half of all Americans carry genetic mutations that interfere with their ability to metabolize folate. Their tissues may be folate deficient, even when their diet is not ... Because Metafolin comes pre-methylated, it is readily usable by the cells, and more efficiently crosses the blood-brain barrier, which mediates the uptake of circulating nutrients" - See the 7/16/03 newsletter regarding depression and folate. This might be a consideration. See Metafolin at iHerb. Abstracts from this week's Doctor's Guide Nutrition/Dietetics:
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