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> Acomplia (rimonabant)
Acomplia (rimonabant)
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News & Research:
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Study Suggests Caution On A New Anti-obesity Drug In Children - Science
Daily, 5/8/08
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Study Shows Weight-Loss Drug Rimonabant Associated With Severe Adverse
Psychiatric Events - Doctor's Guide, 11/15/07 -
"patients given rimonabant had a 4.7kg greater weight reduction after one
year than did those given placebo. However, patients given rimonabant were
at 40% higher risk of having adverse events or serious adverse events.
Patients given rimonabant were 2.5 times more likely to discontinue
treatment because of depressive disorders than were those given placebo, and
three times more likely to discontinue treatment due to anxiety" -
Note: 4.7 kg is 10.3 pounds.
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European Medicines Agency Recommends Acomplia Must Not Be Used in Patients
on Antidepressants or With Major Depression - Doctor's Guide, 7/19/07
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Weight loss pill
warning issued - BBC News, 7/19/07
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Anti-obesity Drug May Prevent And Treat Obesity-related Liver Disease -
Science Daily, 7/2/07
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Rimonabant May Reduce Risk for Diabetes Complications - Medscape,
12/7/06 - "At the end of 1 year, patients receiving
rimonabant 20 mg had an average weight loss of 5.3 kg, compared with 1.4 kg
in the placebo group. Average levels of HbA1C decreased by 0.7 percent in
the rimonabant 20-mg group from a baseline level of 7.3%, but increased in
the placebo group by 0.1%. In fact, 43% of all subjects treated with
rimonabant 20 mg/day achieved an HbA1C level of less than 6.5%, compared
with just 21% in the placebo group"
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New Data Shows Rimonabant Benefited Patients with Type 2 Diabetes by
Improving Blood Sugar Control, Reducing Weight and Acting on Other
Cardiometabolic Risk Factors - Doctor's Guide, 12/5/06 -
"treatment-naive type 2 diabetes patients receiving
rimonabant 20mg per day for a duration of six months significantly lowered
their HbA1c levels by 0.8% from a baseline value of 7.9 as compared to a
reduction of 0.3% in the placebo group (P =.002). In addition, patients with
an HbA1c level greater than or equal to 8.5% at baseline, significantly
reduced their HbA1c by 1.9% with rimonabant as compared to 0.7% with
placebo"
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Acomplia May Be Effective for Diabetes - WebMD, 10/26/06 -
"improvements in cholesterol and blood sugar were
twice what would have been expected from weight loss alone, indicating that
the weight loss drug has an independent effect on these diabetes risk
factors"
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Latest Weight-Loss Pill Offers Modest Results, Blocks 'Munchies' -
Doctor's Guide, 10/19/06
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Acomplia Shows 'Modest' Weight Loss - WebMD, 10/17/06 -
"In a year's time, they lost about 11 more pounds,
on average, than those taking the placebo"
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Obesity pill now available in UK - BBC News, 6/29/06
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Acomplia Cuts Diabetes Patients' Risks - WebMD, 6/12/06 -
"Acomplia's beneficial effect on blood sugars and
fats went 57% beyond the benefit that would have been expected from weight
loss alone"
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Rimonabant May Reduce Weight and Cardiovascular Risk Factors - Medscape,
4/18/06
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Up to Half of Metabolic Improvement Seen With Rimonabant Is Attributable to
Drug Rather Than Weight-Loss Alone - Doctor's Guide, 3/15/06
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Sanofi-aventis Received from the FDA an Approvable Letter for Rimonabant for
Weight Management and a Non Approvable Letter for Smoking Cessation -
Doctor's Guide, 2/20/06
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Medication Shows Modest Benefit In Reducing Weight, Improving HDL,
Triglyceride Levels - Science Daily, 2/16/06
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RIO-North America Study Shows Rimonabant Maintains Improvements in Multiple
Cardiometabolic Risk Factors for Up to 2 Years - Doctor's Guide, 2/15/06
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Can New Diet Pill Keep the Weight Off? - WebMD, 2/14/06
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New Obesity Drug May Help Heart, Too - WebMD, 11/16/05
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Rimonabant Shows Promise for Prevention of Type 2 Diabetes - Medscape,
9/19/05
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Rimonabant Study Shows Significant Improvements in Hba1c and Cardiometabolic
Risk Factors in People With Type 2 Diabetes - Doctor's Guide, 6/16/05
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Rimonabant Reduces Lipids, Weight, and Adiposity - Medscape, 6/14/05
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Rimonabant May Reduce Weight and Cardiovascular Risk Factors - Medscape,
4/18/05
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New Weight Loss Drug May Help Dieters - WebMD, 4/14/05
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Diet Pill Acomplia Keeps the Pounds Off - Doctor's Guide, 3/8/05
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Patients Keep Smaller Waistline, Less Weight After Two Years on Rimonabant
Therapy - Doctor's Guide, 3/8/05
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Anti-Obesity Drug No Cure-All - mercola.com, 3/8/05
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Will a New Drug Melt the Pounds? It May, but Doctors Urge Caution - NY
Times, 12/5/04
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Smoking Cessation Drug Also Keeps Weight Off - Doctor's Guide, 11/15/04
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Anti-Obesity Pill Might Fight Drug Abuse - Intelihealth, 11/15/04 -
"The French pharmaceutical firm Sanofi-Aventis plans
to seek federal approval for rimonabant next year"
- Rimonabant Maintains
Both Weight and Waist Reductions at 2 Years - Medscape, 11/10/04
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Early Improvement in Coronary Risk Factor Profile with Rimonabant Persists
At 2-Year Follow-up - Doctor's Guide, 11/10/04
- Experimental
Diet Drug [Acomplia] Has Staying Power - WebMD, 11/9/04
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Can taking a pill really help you to lose weight and stop smoking? -
Guardian Unlimited, 9/2/04
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Investigative Drug Rimonabant Helps Obese Subjects Lose Weight and Reduce
Waist Size - Doctor's Guide, 8/30/04
- A New 'Wonder'
Drug for Weight Loss? - WebMD, 8/30/04
- 8 1/2 Pounds
Lost in 16 Weeks With New Drug - WebMD, 6/17/04
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A New Smoking and Obesity Drug? - Physician's Weekly, 4/19/04
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Rimonabant Equally Effective as Smoking Cessation or Weight Loss Treatment
- Doctor's Guide, 3/10/04
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