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Recent Longevity News for the week ending 2/22/17

Vitamin B3 prevents glaucoma in laboratory mice - Science Daily, 2/16/17 - "In mice genetically predisposed to glaucoma, vitamin B3 added to drinking water is effective at preventing the disease ... The vitamin administration was surprisingly effective, eliminating the vast majority of age-related molecular changes and providing a remarkably robust protection against glaucoma. It offers promise for developing inexpensive and safe treatments for glaucoma patients" - See vitamin B3 at Amazon.com.

B vitamins reduce schizophrenia symptoms, study finds - Science Daily, 2/16/17 - "A review of worldwide studies has found that add-on treatment with high-dose b-vitamins -- including B6, B8 and B12 -- can significantly reduce symptoms of schizophrenia more than standard treatments alone ... B-vitamin interventions which used higher dosages or combined several vitamins were consistently effective for reducing psychiatric symptoms, whereas those which used lower doses were ineffective"

Vitamin D Tied to Lower Risk of Colds, Infections - WebMD, 2/16/17 - "The 12 percent reduction meant that 33 people would need to take vitamin D supplements to prevent one acute respiratory tract infection. The benefit of the supplements was greater among people who took daily or weekly vitamin D without additional large doses ... The protective effect of vitamin D supplements was strongest for those with severe vitamin D deficiency. In this group, only four people would need to take vitamin D supplements to prevent one acute respiratory infection" - See vitamin D at Amazon.com.

Increased levels of active vitamin D can help to optimize muscle strength - Science Daily, 2/15/17 - "Individuals with an increased lean mass, and muscle bulk, had a higher level of active vitamin D in the bloodstream" - See vitamin D at Amazon.com.

Abstracts from this week:

Supplemental Selenium May Decrease Ovarian Cancer Risk in African-American Women - J Nutr. 2017 Feb 15 - "Women with the highest intakes of supplemental selenium (>20 μg/d) had an ~30% lower risk of ovarian cancer than those with no supplemental intake (OR: 0.67"

Supplementation with macular carotenoids reduces psychological stress, serum cortisol, and sub-optimal symptoms of physical and emotional health in young adults - Nutr Neurosci. 2017 Feb 15:1-11 - "Oxidative stress and systemic inflammation are the root cause of several deleterious effects of chronic psychological stress. We hypothesize that the antioxidant and anti-inflammatory capabilities of the macular carotenoids (MCs) lutein, zeaxanthin, and meso-zeaxanthin could, via daily supplementation, provide a dietary means of benefit ... Supplementation with the MCs significantly reduces stress, cortisol, and symptoms of sub-optimal emotional and physical health" - See carotenoids supplement at Amazon.com.  Recent similar study:

  • Clinical Study Shows AstaReal(R) Astaxanthin Effective in Reducing both Mental and Physical Fatigue - yonhapnews.co.kr, 11/7/16 - "AstaReal® astaxanthin significantly reduced perceived symptoms of mental and physical fatigue compared to the placebo. These included improvements in clarity of thinking, concentration, motivation, and mood. Irritation and feeling of body heaviness were reduced. In the calculation test, an increase in errors observed in the placebo during the second half of the test was almost eliminated in the astaxanthin group. Supplementation with astaxanthin also significantly reduced salivary cortisol, a biomarker for stress" - [Nutra USA] - See astaxanthin at Amazon.com.

Differential effects of metformin on age related comorbidities in older men with type 2 diabetes - J Diabetes Complications. 2017 Jan 28 - "age-related comorbidity (ARC) ... frailty-related diseases (FRD) ... 'Healthy Class' (53.6%): metformin reduced likelihoods of all ARCs (from 0.14% in dementia to 6.1% in CVD). 'High Cancer Risk Class' (11.6%): metformin reduced likelihoods of CVD (13.3%), cancer (45.5%), depression (5.0%), and FRD (13.7%). 'High CVD Risk Class' (17.4%): metformin reduced likelihoods of CVD (48.6%), cancer (3.2%), depression (2.8%), and FRD (6.3%). 'High Frailty Risk Class' (17.2%): metformin reduced likelihoods of CVD (18.8%), cancer (3.9%), dementia (3.8%), depression (15.6%), and FRD (23.8%)" - See metformin at IAS.

The Dietary Inflammatory Index Is Associated with Colorectal Cancer Risk in the Multiethnic Cohort - J Nutr. 2017 Feb 8. pii: jn242529 - "Among all participants, more-proinflammatory diets (highest quartile compared with lowest quartile) were associated with an increased risk of CRC (HR: 1.21" - Related study from a couple weeks ago:

Supplemental Citrulline Is More Efficient than Arginine in Increasing Systemic Arginine Availability in Mice - J Nutr. 2017 Feb 8 - "Arginine is considered to be an essential amino acid in various (patho)physiologic conditions of high demand. However, dietary arginine supplementation suffers from various drawbacks, including extensive first-pass extraction. Citrulline supplementation may be a better alternative than arginine, because its only fate in vivo is conversion into arginine ... Citrulline supplementation is more efficient at increasing arginine availability than is arginine supplementation itself in mice" - See BulkSupplements Pure L-Citrulline DL-Malate 2:1 Powder at Amazon.com and BulkSupplements Pure L-Arginine HCL Powder at Amazon.com.

Preventive effect of dietary astaxanthin on UVA-induced skin photoaging in hairless mice - PLoS One. 2017 Feb 7;12(2):e0171178 - "Our results indicate that dietary astaxanthin accumulates in the skin and appears to prevent the effects of UVA irradiation on filaggrin metabolism and desquamation in the epidermis and the extracellular matrix in the dermis" - [Nutra USA] - See BioAstin at Amazon.com.  Note:  Astaxanthin may also reduce cortisol which is why I added it to my sleep coctail:

  • Clinical Study Shows AstaReal(R) Astaxanthin Effective in Reducing both Mental and Physical Fatigue - yonhapnews.co.kr, 11/7/16 - "AstaReal® astaxanthin significantly reduced perceived symptoms of mental and physical fatigue compared to the placebo. These included improvements in clarity of thinking, concentration, motivation, and mood. Irritation and feeling of body heaviness were reduced. In the calculation test, an increase in errors observed in the placebo during the second half of the test was almost eliminated in the astaxanthin group. Supplementation with astaxanthin also significantly reduced salivary cortisol, a biomarker for stress" - [Nutra USA] - See astaxanthin at Amazon.com.

Neat Tech Stuff / "How To's":

How to stream movies from your computer to your TV via you iPhone:

  1. Requirements: AnyDVD, Videosteam for Google Chromecast, Nero Recode (part of Nero Platinum) and Chromecast.

  2. With AnyDVD activated, use Nero Recode to convert the DVD to the .mp4 format in a subdirectory of your PC video folder.

  3. Install Chromecast on your TV.

  4. Download the Videosteam for Google Chromecast Google Chrome add-on on your PC and the Videosteam for Google Chromecast app on your iPhone and follow the dialog.

  5. Sync the videos by selecting "Sync" in the Videostream app on your iPhone then select the video.

  6. To have you computer shutdown automatically after the movie, see: Put a shutdown timer on your Windows desktop with this command - CNET, 6/9/16 - https://www.cnet.com/how-to/put-a-shutdown-timer-on-your-windows-desktop-with-this-command/

  7. Added advantage:  You can drag the .mp4 into the iCloud Drive directory on your PC.  Then select iCloud on your iPhone or iPad and select the video to download it to your iPhone or iPad.  Make sure you're connected to a WiFi or it will eat up your data.  Also, you'll probably need to upgrade your iCloud data storage plan to the 99 cents per month plan for 100 GB.  Plug it into the iPod jack on your car’s stereo.  Plus in the .mp4 format you can put it on a SD card or memory stick to view on any computer.

  8. BTW, Looper is one of the best brainteaser movies out there.

 

Health Focus (Vitamin D):

 

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