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Welcome to the Quality Counts. For those health conscious consumers and medical professionals that are looking to purchase nutritional supplements, vitamins, herbs, learning about medications, losing weight, health food, low carbs, high protein nutrition, and exercise, you have come to the right place. Quality Counts serves both the medical practitioner and consumer interested in nutritional therapy and alternative medicine.
Home > Health Conditions > Inflammation
Inflammation
Related Topics:
Popular Medications:
Popular Supplements:
Alternative News:
-
Inflammation:
Chronic - Life Extension Foundation
- Bursitis
- Vitacost Health Library
-
Natural Remedies for Inflammation - thenutritionreporter.com
-
MSM and DMSO
- thenutritionreporter.com
-
Diets With High Omega-6:Omega-3 Ratios Enhance Risk for Depression,
Inflammatory Disease - Medscape, 4/25/08 -
"Whereas the early hunter-gatherers had a dietary omega-6:omega-3 ratio of
2:1 to 3:1, this ratio is now 15:1 to 17:1 in North America today ... It is
believed that these dietary changes might be related to increases in
inflammatory-related diseases, including depression and cardiovascular
disease ... at higher levels of depressive symptoms, as the omega-6:omega-3
ratio increased, there was a marked increase in proinflammatory cytokine
levels ... compared with the study participants who did not have syndromal
depression, the 6 participants who had depression had significantly higher
omega-6:omega-3 ratios and higher levels of proinflammatory cytokines" - See
Mega Twin EPA at iHerb
.
-
"Anti-Inflammatory" Diet Improves Postprandial Glucose, CV Health -
Medscape, 1/23/08 - "Specific recommendations to
improve postprandial glucose and triglycerides are as follows: ... Select
high-fiber carbohydrates with low glycemic index, including vegetables,
fruits, whole grains, legumes, and nuts ... At all 3 meals, consume lean
protein"
-
Coffee consumption is associated with higher plasma adiponectin
concentrations in women with and without type 2 diabetes: a prospective
cohort study - Diabetes Care. 2007 Dec 10 -
"High consumption of caffeine-containing coffee is associated with higher
adiponectin and lower inflammatory marker concentrations"
-
Study gives vitamin K anti-inflammation boost - Nutra USA, 12/3/07 -
"Limited in vitro data support the inverse
association between vitamin K and interleukin-6, and this may influence the
association between vitamin K and other cytokines, such as osteoprotegerin"
- [Abstract]
- See
vitamin K products at iHerb
.
-
Vitamin K and Vitamin D Status: Associations with Inflammatory Markers in
the Framingham Offspring Study - Am J Epidemiol. 2007 Nov 15 -
"Vitamin K status, measured by plasma phylloquinone
concentration and phylloquinone intake, was inversely associated with
circulating inflammatory markers as a group and with several individual
inflammatory biomarkers" - See
vitamin K products at iHerb
.
-
Exercise May Play Role In Reducing Inflammation In Damaged Skin Tissue -
Science Daily, 11/28/07 - "moderate exercise sped up
how fast wounds heal in old mice ... the improved healing response “may be
the result of an exercise-induced anti-inflammatory response in the wound.”
... Cytokines are molecules that signal and direct immune cells, such as
macrophages, to the site of an infection ..."
-
Fitness Reduces Inflammation, Study Suggests - Science Daily, 7/6/07 -
"the research “certainly suggests that fitness may
be associated with a decrease in inflammation even independent of body fat
and several things, and the mechanism may involve a parasympathetic
anti-inflammatory reflex"
-
Diets With High Omega-6:Omega-3 Ratios Enhance Risk for Depression,
Inflammatory Disease - Medscape, 4/26/07 -
"Whereas the early hunter-gatherers
had a dietary omega-6:omega-3 ratio of 2:1 to 3:1, this ratio is now 15:1 to
17:1 in North America today ... compared with the study participants who did
not have syndromal depression, the 6 participants who had depression had
significantly higher omega-6:omega-3 ratios and higher levels of
proinflammatory cytokines"
-
Depressive Symptoms, omega-6:omega-3 Fatty Acids, and Inflammation in Older
Adults - Psychosom Med. 2007 Mar 30 -
"Diets with high n-6:n-3 PUFA ratios
may enhance the risk for both depression and inflammatory diseases"
-
Soy Consumption, Markers of Inflammation, and Endothelial Function: A
cross-over study in postmenopausal women with the metabolic syndrome -
Diabetes Care. 2007 Apr;30(4):967-73 -
"Short-term soy nut consumption
reduced some markers of inflammation and increased plasma nitric oxide
levels in postmenopausal women with the metabolic syndrome"
-
Natural
Solutions for Inflammation - Dr. Murray's Natural Living, 5/23/06
- Does
Inflammation Cause Heart Disease? - Dr. Weil, 5/18/06
- How to fight
inflammation - MSNBC, 5/12/06 - "The
intensity of this general inflammation can be measured by blood tests for
markers like C-reactive protein (CRP), which is produced by the liver during
periods of inflammation ... People with increased levels of CRP seem to have a
greater risk of heart disease from damage to their blood vessels ... Chronic
inflammation may also be connected to cancers of the esophagus, stomach, colon
and liver"
-
MIT
Research Links Cancer, Inflammatory Disease - Science Daily, 4/5/06 -
"The studies uncovered a surprising
link between inflammatory diseases and cancer that may change how these
diseases are treated in the future"
-
Reducing inflammation is the key to a stronger ticker. Six practical steps
- deliciouslivingmag.com, 2/06
-
Supplements to decrease inflammation - deliciouslivingmag.com, 2/06
- Influencing
Inflammation? - Dr. Weil, 11/3/05
-
Fish Help the Heart by Fighting Inflammation - WebMD, 7/5/05 -
"compared with those who said they
didn't eat fish, those who ate at least 10.5 ounces of fish per week had 33%
lower C-reactive protein and 33% lower tumor necrosis factor-alpha (another
indicator of inflammation) levels as well as much lower levels of other
signs of inflammation"
-
Healthy Gums May Help Fight Alzheimer's - WebMD, 6/20/05 -
"Brushing your teeth may be one of
many ways to help keep your mind healthy and lower the risk of Alzheimer's
disease"
-
Eating Oily Fish May Reduce Inflammation - Science Daily, 3/24/05 -
"This research group recently
identified a new class of aspirin-triggered bioactive lipids, called
resolvins, the activity of which may in part explain the beneficial effects
of omega-3 fatty acids"
- The dangers of inflammation - Functional Foods & Nutraceuticals, 2/05
- Effect of CLA supplementation on immune function in young healthy volunteers - Eur J Clin Nutr. 2005 Jan 12 -
"CLA
supplementation also decreased the levels of the proinflammatory cytokines, TNF-alpha and IL-1beta (P<0.05), but increased the
levels of the anti-inflammatory cytokine, IL-10 ... This is the first study to show that CLA, a fatty acid naturally found in dairy and meat products, can beneficially affect immune function in healthy human volunteers" - See
iHerb
or
Vitacost CLA products.
- Ease inflammation - Delicious Living, 11/04
- Inflammation Syndrome a Red-Hot Topic - Natural Foods Merchandiser, 9/03 -
"What are some of the key anti-inflammatory supplements? ... At the top of the
list are omega-3 fish oils, gamma-linolenic acid (GLA, an omega-6 fat that behaves more like an omega-3) and vitamin E. Several studies have shown that natural vitamin E supplements lower
CRP levels by 30 percent to 50 percent"
- Fish Oil Supplementation Reduces Severity of Exercise-Induced Bronchoconstriction in Elite Athletes - Am J Respir Crit Care Med. 2003 Aug 6 -
"These data suggest that dietary fish oil supplementation has a markedly protective effect in suppressing EIB in elite athletes and this may be attributed to
their anti-inflammatory properties"
- Habitual Dietary Intake of n-3 and n-6 Fatty Acids in Relation to Inflammatory Markers Among US Men and Women - Circulation. 2003 Jun 23 -
"These results suggest that n-6 fatty acids do not inhibit the antiinflammatory effects of n-3 fatty acids and that the combination of both types of fatty acids is associated with the lowest levels of
inflammation. The inhibition of inflammatory cytokines may be one possible mechanism for the observed beneficial effects of these fatty acids on chronic inflammatory-related diseases" - See Mega Twin EPA at
iHerb
or
Vitacost .
- Eating to Ease Inflammation? - Dr. Weil, 5/7/03
- Anti-Inflammatory Diet Plus Fish Oil Effective for Rheumatoid Arthritis - New Hope Natural Media, 5/1/03 -
"An anti-inflammatory diet and
fish oil supplements are both helpful for people with rheumatoid arthritis (RA), but combining them has an even greater effect ... The anti-inflammatory diet improved joint pain, swelling, and overall ability to function by 14%, while the Western diet did not improve symptoms or
functioning. Benefits were observed with the addition of fish oil, bringing total improvement to 17% in those eating a Western diet and 37% in those eating the anti-inflammatory diet. Furthermore, the need for anti-inflammatory medications was significantly reduced for those receiving fish oil on both diets,
although the group eating the anti-inflammatory diet had greater medication reduction. Medication usage increased for those on the Western diet plus placebo"
- Protecting Blood Vessels From Stress - WebMD, 1/15/02 -
"vitamins can improve blood flow and prevent the long-term development of atherosclerosis -- or
hardening of the arteries -- when given in combination with an amino acid known as L-arginine ... antioxidants might work together with L-arginine to prevent inflammation in the branch areas of blood vessels ... although antioxidants may not
reverse or repair pre-existing damage within blood vessels, they may slow the long-term progression of atherosclerosis"
- See
iHerb
and
Vitacost
l-arginine products.
- Can Herbs Combat Inflammation? - Dr. Weil, 12/3/02 -
"Take 400 to 600 milligrams of turmeric extracts (available in tablets or capsules) three times per day or as directed on the
product label. Whole turmeric is more effective than isolated curcumin, its major constituent. Look for products standardized for 95% curcuminoids. Be patient: the full benefit takes two months to develop. Don’t use turmeric if you have gallstones or bile duct dysfunction"
- Scientists Say Inflammation Even Worse For Heart Than Cholesterol - Intelihealth, 8/6/02
- A Message from Dr. Cooper - Wellness Insider, 5/22/02 -
"the higher the pulse pressure, the greater the risk of having an elevated CRP ... "the findings suggest
that a wide pulse pressure is associated with higher levels of inflammation," and that inflammation is increasingly "being seen as a risk factor for adverse cardiovascular events." ... Several things are known to lower CRP, including aspirin, vitamin E, and
statins (cholesterol lowering drugs). Unpublished data from The Cooper Institute has also shown that exercise lowers CRP ... Early data from the double-blind, placebo-controlled clinical trial of Cooper Complete multivitamins is also showing a reduction of CRP"
- Active Life Keeps Brain Healthy - WebMD, 5/21/02 -
"An active lifestyle -- even if begun only in middle age -- spurs brain-cell growth and lowers
risk of Alzheimer's disease ... In another study published in the same issue of the Annals of Neurology, researchers find that a particular chemical in the blood may be linked to Alzheimer's and other dementing diseases ... The chemical is called hs-CRP. It is a sign of inflammation
-- the body's protective response to injury or infection"
- Omega-3 Fatty Acid Reduces Pro-Inflammatory Cytokines In Heart Transplant Patients - Doctor's Guide, 4/11/02 -
"gave 25 stable heart transplant
patients two capsules of omega-3 fatty acid daily - each capsule contained 500 mg of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) ... The results suggest that omega-3 fatty acid
supplementation increased concentrations of the anti-inflammatory interleukin (IL)-10, from 119 to 268 pg/mL (p=0.00008). There were reductions in systemic levels of pro-inflammatory IL-12, from 473 to 376 pg/mL
(p=0.001), and IL-6, from 695 to 569 pg/mL (p<0.0001)"
- Soy Fights Pain - WebMD, 3/15/02
- Weight Loss Eases Harmful Inflammation - WebMD, 2/4/02 -
"They measured levels of a blood chemical called "C-reactive protein," or CRP. This chemical goes
up when inflammation in the body rises. Then, 25 of the women were put on a weight-loss program ... On average, CRP levels fell by 32% after a weight loss of about 33 pounds over 14 months"
-
Chronic
Inflammation, The Epidemic Disease of Aging - Life Extension Magazine, 1/02 -
"Chronic inflammation inflicts devastating effects, especially as humans grow older. The pathological consequences of inflammation are fully documented in the medical
literature. Regrettably, the dangers of systemic inflammation continue to be ignored, even though proven ways exist to reverse this process"
-
Inflammation
and Heart Disease - Life Extension Magazine, 1/01
- Diet and Exercise Alone Shown to Lower C-Reactive Protein - Doctor's Guide, 11/14/01 -
"Hs-CRP, a marker of low level inflammation, has been found to be a strong predictor of myocardial
infarction and stroke in men and women, as well as subsequent clinical events in patients following major cardiac events ... a structured program involving a low-fat, Mediterranean diet and a supervised, three-times weekly exercise program for three months ... Values of hs-CRP dropped 31 percent after the three
months ... body fat was reduced by 5 percent ... exercise capacity improved 36 percent"
- Robert Culp spies arthritis relief - USA Today, 7/20/01 -
"MSM — sometimes called DMSO2 — is similar, but has an additional oxygen molecule and a
few advantages over DMSO ... Unlike its parent, MSM does not produce a sweet, garlic-like odor in the user. While DMSO was used primarily as a topical lotion, its ability to permeate tissue also brought contaminants with it. Impure industrial-grade DMSO, not of a pharmceutical quality, became common. Although MSM is
available in lotion form, it is more commonly taken orally ... The most common theory is that MSM relieves arthritic pain through anti-inflammatory processes, perhaps through stimulating the circulation of oxygen-rich blood ... Other experts theorize that DMSO and MSM may both owe their efficacy to rich organic
sulfur compounds"
- Vitamin E Works As Anti-Inflammatory Agent In Type II Diabetes - Doctor's Guide, 7/10/00
- Scientists Discover How Aspirin Reduces Inflammation - Doctor's Guide, 11/4/98
- Drug therapy of activated arthrosis. On the effectiveness of an enzyme mixture versus diclofenac - Medline, 1996 (I thought this study was interesting because it showed that
Wobenzym® was as effective as diclofenac. In another study, diclofenac was show to be as effective as Vioxx. That said, it would make sense that Wobenzym should be as effective as Vioxx.)
General Information:
-
Inflammation - American Academy of Family Physicians
- Inflammation - emedicine.com
-
Inflammation - FamilyDoctor.org
- Treatments for inflammation
- Medifocus.com
Other News:
-
Inflammatory Markers and Albuminuria Independently Predict Heart Failure
- Medscape, 5/2/08 - "Interleukin (IL)-6, C-reactive
protein, and macroalbuminuria are significant predictors of congestive heart
failure, independent of obesity and other established risk factors"
-
Role of
Inflammation in Initiation and Perpetuation of Atrial Fibrillation -
Medscape, 11/19/07
-
Salary, Schooling, Inflammation Linked - WebMD. 11/19/07
-
UCSD Researchers Discover Inflammation, Not Obesity, Cause of Insulin
Resistance - Doctor's Guide, 11/6/07 - "The
research also proved that obesity without inflammation does not result in
insulin resistance ... when an animal or a human being becomes obese, they
develop steatosis, or increased fat in the liver. The steatosis leads to
liver inflammation and hepatic insulin resistance"
-
Inflammation, Metabolic Syndrome, Erectile Dysfunction, and Coronary Artery
Disease: Common Links - Eur Urol. 2007 Aug 13 -
"Increased circulating levels of inflammatory and endothelial-prothrombotic
compounds are related to the presence and severity of ED"
-
Inflammation May Play Role In Metastasis Of Prostate Cancer - Science
Daily, 3/18/07 - "inflammation
associated with the progression of tumors actually plays a key role in the
metastasis of prostate cancer"
-
Strong Link Seen Between Depression, Inflammation - Clinical Psychiatry
News, 6/06 - "depressed patients
have elevated inflammatory markers—such as interleukin-6 and C-reactive
protein. In fact, the levels of proinflammatory cytokines correlate with the
severity of depressive symptoms in studies. In addition, administration of
cytokine antagonists can effectively reverse depressive symptoms in
patients"
-
White Blood Cell Count, Inflammation Linked to Cancer Deaths - Doctor's
Guide, 1/24/06 - "those with a
higher white blood cell count, a sign of inflammation, were more likely to
die of cancer ... The study also suggests that aspirin may have a greater
protective effect against cancer for those with high WBC"
-
Inflammation Markers Tied to Narrow, Blocked Arteries - Doctor's Guide,
1/23/06 - "Hardening of the arteries
in the legs is strongly associated with biological markers of inflammation,
which may be a warning sign of heart trouble"
-
Caloric Restriction Appears to Prevent Primary Aging in the Heart -
Doctor's Guide, 1/12/06 - "Our
hypothesis is that low-grade, chronic inflammation is mediating primary
aging"
-
Inflammation Linked To Chronic Pain: Study - Science Daily, 12/7/05
-
Extra Weight May Age You Faster - WebMD, 5/25/05 -
"inflammation burns out white blood
cells faster, and the effort of replacing them wears down the telomeres"
-
Simple Blood Test May Help To Predict Cardiovascular Risk In Older Women
- Science Daily, 3/31/05 -
"Increasing evidence supports a role for inflammation in the development of
atherosclerosis, thickening and hardening of the arteries ... Women in the
fourth quartile (highest WBC) had a doubled risk for coronary heart disease
death compared with women in the first quartile (lowest WBC) ... the WBC
count was an independent predictor of coronary heart disease risk,
comparable in magnitude to C-reactive protein (CRP)"
- Metabolic Syndrome Associated with Cognitive Decline in Elderly Persons - Doctor's Guide, 11/9/04 -
"persons with the
metabolic syndrome (n = 1016) were 20 percent more likely to develop cognitive impairment ... Those with both metabolic syndrome and high inflammation (n = 348) were 66 percent more likely to have cognitive impairment than those without the metabolic syndrome"
- Aspirin May Delay Prostate Cancer, Extend Life - WebMD, 10/4/04 -
"evidence is mounting that prostate cancer may develop
in areas with chronic inflammation"
- Longevity May Have Roots In Childhood - Science Daily, 9/20/04 -
"Infectious diseases cause chronic inflammation in the blood that, decades
later, leads to heart attacks, strokes and cancers – the classic killers of old age"
- UCSD Researchers Are First To Demonstrate Molecular Link Between Inflammation And Cancer - Science Daily, 8/6/04
- Missing Link Ties Cancer to Chronic Infection - WebMD, 8/5/04 -
"Infections provoke an immune response from the body. Part of this response is inflammation. Inflamed tissues
swell, redden, and leak fluids full of chemical signals to the immune system"
- Fast Food Breakfast Triggers Inflammation - WebMD, 4/19/04
- The Secret Killer - Time Magazine Cover Story, 2/23/04 -
"Inflammation is the body's first defense against infection, but when it goes awry, it can lead to heart
attacks, colon cancer, Alzheimer's and a host of other diseases ... exercise more, eat better and floss"
- Examining Inflammation - Physician's Weekly, 2/2/04
- Blood test can warn of heart attack - USA Today, 10/22/03
- Hormone Replacement Therapy Beneficial in Post-Menopausal Women with Rheumatoid Arthritis - Doctor's Guide, 8/14/03 -
"Women with rheumatoid arthritis (RA) who are receiving hormone replacement therapy (HRT) show greater improvements in disease activity, inflammation, bone mineral density, and radiological progression than women not receiving HRT ... Treatment with HRT
also led to better control of inflammation"
- Inflammation May Affect Osteoarthritis - WebMD, 8/1/03
- Depression in Obese Men Associated with Increased C-Reactive Protein - Doctor's Guide, 7/15/03
- When Diet Doesn't Lower Cholesterol - WebMD, 7/7/03 -
"Study participants whose CRP levels were originally below average saw dramatic
reductions in cholesterol after 12 weeks on the DASH diet. Total cholesterol dropped by almost 9% and LDL, or bad cholesterol, dropped by almost 12%. In participants with higher than average CRP levels, total and LDL cholesterol levels dropped by just 3% each ... This is the first study to suggest that inflammation
impacts the response to a traditional cholesterol lowering diet ... Several recent studies have shown that people who lost weight on high-protein, relatively high-fat diets lowered their cholesterol, suggesting that weight loss alone, no matter how it is achieved, plays a significant role in lowering cholesterol"
- Inflammation Linked to Age-Related Maculopathy - Doctor's Guide, 6/11/03 -
"2 physiological signs of systemic inflammation, high white blood
cell (WBC) count and low serum albumin levels, were associated with long term incidence of lesions characteristic of ARM ... Specifically, higher WBC
count at baseline was linked to 2 early signs of ARM, an increase in large retinal drusen and RPE depigmentation, as well as progression of ARM. Lower serum albumin was associated with a late sign of ARM, exudative macular
degeneration"
- Infection, Autoimmune Reaction, Inflammation Trigger Heart Attack - WebMD, 5/12/03
- Effect of metformin and sulfonylurea on C-reactive protein level in well-controlled type 2 diabetics with metabolic syndrome - Endocrine 2003 Apr;20(3):215-8 -
"CRP level was significantly lower in patients using metformin for blood glucose control compared with those using glibenclamide, 5.56
and 8.3 mg/L, respectively ... The data showed that metformin decreases the level of circulating CRP, a marker of inflammation, more than glibenclamide"
- C-reactive protein is independently associated with fasting insulin in nondiabetic women - Arterioscler Thromb Vasc Biol 2003 Apr 1;23(4):650-5 -
"increasing levels of CRP were associated with a stepwise gradient in odds for elevated fasting insulin among both lean and overweight women"
- Estrogen Patch More Heart-Friendly Than Pills - WebMD, 4/15/03 -
"the C-reactive protein increased to an average of almost twice their baseline levels
when the women took oral estrogen replacement, but not when they were on the estrogen patch"
- Birth Control Pill Linked to Heart Disease Protein - WebMD, 4/11/03 -
"young women who took birth control pills had twice as much C-reactive protein in their blood as a
similar group of women who did not use birth control pills ... It is possible that oral contraceptive use promotes inflammation"
- C-Reactive Protein Linked to Stroke Risk - WebMD, 4/7/03
- Aspirin May Protect Against Parkinson's Disease - Doctor's Guide, 4/4/03 -
"Dr. Ross hypothesized that since
inflammation is thought to play a role in the neurodegenerative process leading to Parkinson's disease, anti-inflammatory drugs such as aspirin may help slow the progression of the disease ... The study showed that there were 17.7 cases of Parkinson's per
10,000 person-years in the patients who never took aspirin or were taking it on one occasion, compared with 6.8 cases per 10,000 person-years in the men who were taking aspirin on both assessments ... No conclusion could be drawn regarding the use of other NSAIDs and Parkinson's, he said,
because too few of the men reported taking the drugs" - See drugstore.com aspirin
products.
- Ezetimibe Plus Simvastatin Reduces C-Reactive Protein in Patients with High Cholesterol - Doctor's Guide, 4/4/03 -
"C-reactive protein is
considered an emerging risk factor and risk marker for coronary heart disease ... the levels of C-reactive protein were about halved when the pooled ezetimibe plus simvastatin results were compared with simvastatin alone. The
combination produced about a 34.8% reduction compared to an 18.2% reduction if the statin was used as monotherapy"
- Level Of C-Reactive Protein Tied To Abdominal Aortic Aneurysm Size - Doctor's Guide, 3/13/03
- Statins/Beta Blockers Impact On Certain C-Reactive Protein Levels - Doctor's Guide, 1/29/03 -
"Some 93% of the 89 patients who did not use
beta-blockers and were in the highest CRP category and had exercise-induced
ischaemia, compared with 42% among patients in the lower four categories. Similarly, 94% of the 67 patients who did not use
statins and were in the highest CRP category had exercise-induced ischaemia, compared with 44% in the lower four categories"
- CRP improves cardiovascular risk prediction in metabolic syndrome - American Hearth Association, 1/28/03
- New Heart Disease Blood Test Discouraged - WebMD, 1/27/03 -
"hs-CRP is most
useful when a doctor is "sitting on the fence" while determining the right treatment strategy for a person with intermediate risk of heart disease. In those cases -- meaning someone who, based on cholesterol, blood pressure, smoking history, and weight, is believed to have about 10% to 20% increased risk for heart
attack over the next 10 years -- an elevated hs-CRP could tip the scale toward more aggressive treatment"
- Bad Boy in the Blood: CRP - WebMD, 1/15/03 -
"CRP doesn't just mark risk. It contributes to plaque formation in the blood-vessel wall. It promotes
cholesterol uptake ... The most dazzling observation has been that in postmenopausal women, even those with low cholesterol levels, CRP identifies a three-fold increased risk for coronary artery disease ... When they added CRP to these cells, they saw dramatic effects. The
cells began to secrete a substance called PAI-1. Increased PAI-1 secretion predicts formation of blood clots and heart disease. It also predicts diabetes and the pre-diabetes condition known as metabolic disorder ... You can lower your CRP levels by doing the same things you would do to
lower your cholesterol levels: lose weight, eat fewer calories and a very low fat diet, take the cholesterol-lowering drugs known as statins, and the natural form of vitamin E"
- Finger Arthritis Predicts Heart Disease - WebMD, 1/15/03 -
"Men with osteoarthritis (OA) in any finger joint were 40%
more likely to die of heart disease than their counterparts without finger OA. ... While "hardening of the arteries" was once thought to result from a buildup of cholesterol, increasing evidence indicates that it's the result of some type of inflammation of blood vessels"
- C-Reactive Protein as a Predictor for Incident Diabetes Mellitus Among Middle-aged Men - Archives of Internal Medicine, 1/13/03 -
"Low-grade
systemic inflammation is associated with an increased risk of type 2 diabetes mellitus in middle-aged men. Inflammation could be one mechanism by which known risk factors for diabetes mellitus, such as obesity, smoking, and hypertension, promote the development of diabetes mellitus"
- Rheumatoid Arthritis Linked With Other Inflammatory Diseases In Study - Doctor's Guide, 12/11/02
- Low-dose Periostat (Doxycycline) Shows Benefits in Patients with Heart Failure - Doctor's Guide, 11/20/02 -
"At six-month follow-up,
sub-antimicrobial dose doxycyline significantly reduced CRP levels by 45.8 percent compared to baseline values (p<0.05). The drug was also associated with a 33.5 percent reduction in interleukin-6 and a 50 percent reduction in metalloproteinase ... The findings are
exciting, since research is now showing that CRP is both a key marker of inflammation leading to future acute coronary events, but also that CRP itself may contribute to the initiation and progression of atherosclerosis"
- Study finds alcohol may lessen inflammation - USA Today, 11/17/02 -
"alcohol exerted the greatest benefit
in those with the highest levels of a chemical called C-reactive protein, CRP, which builds up when arteries become inflamed. Some researchers now believe that CRP itself may be a previously unrecognized cause of heart disease ... Although LDL has long been considered the best measure of heart attack risk, about
half of people who have heart attacks don't have high cholesterol ... "I think this is a fundamental shift in our thinking about (artery) disease""
- Simple Blood Test Predicts Heart Disease - WebMD, 11/13/02
- Inflammation Triggers Heart Attacks - Intelihealth, 11/14/02
- Periodontal Diseases Increase C-Reactive Protein In Haemodialysis Patients - Doctor's Guide, 11/7/02
- Inflammation May Increase Stroke Risk In Men With Hypertension - Doctor's Guide, 11/1/02 -
"The study found that men with systolic
blood pressure (the top number in a blood pressure reading) at or above 140 millimeters of mercury (mm Hg) and elevated levels of inflammation-sensitive plasma proteins (ISP) were four times as likely to have a stroke as were men who had normal blood
pressure and normal ISP levels. Moreover, the inflammatory proteins predicted stroke risk for 10 or more years."
- Pain Relievers May Prevent Alzheimer's - WebMD, 9/23/02 -
"previous studies have suggested that aspirin and other NSAIDs might protect against Alzheimer's disease by reducing
inflammation in the brain"
- C-Reactive Protein, IL-6 Levels Tied to Heart Disease in Postmenopausal Women - Doctor's Guide, 8/28/02 -
"Baseline levels
of the inflammatory biomarkers C-reactive protein (CRP) and interleukin-6 (IL-6) are independently associated with a two-fold increase in risk of healthy postmenopausal women developing coronary heart disease (CHD)"
- Antibiotics Aid Heart Patients - WebMD, 8/19/02 -
"A year later, those who received an antibiotic were 36% less likely to be rehospitalized for a heart attack or chest pain than those who took a placebo ... The question, Mendall
says, is whether the antibiotics are working by fighting infection or inflammation in these patients"
- Increased Inflammation May Play A Role In Vascular Dysfunction In Type 2 Diabetes - Doctor's Guide, 8/1/02
- Ulcer-Causing Bacteria Linked to Stroke - WebMD, 7/8/02 -
"H. pylori causes ulcers in the stomach ... those who had suffered a
stroke from a blocked large artery had significantly higher levels of the more potent strains of the bacteria ... The study also found that levels of a substance known as C-reactive protein (CRP) that indicates inflammation within the body were also higher in the stroke groups. But
patients with the potent strains of H. pylori had the highest CRP levels ... treating patients with H. pylori infection may be an easy way to reduce the risk of stroke"
- New Test Predicts Sudden Death Risk - WebMD, 4/15/02 -
"those who suffered sudden cardiac death had higher levels of a substance called C-reactive protein (CRP) ... CRP is
released when blood vessels are inflamed ... the findings of this study show that the levels of CRP in the blood are even more telling than once thought ... we can intervene with lifestyle counseling and drugs like statins and aspirin"
- Statin Drugs May Fight Alzheimer's, Too - WebMD, 4/9/02 -
"Statins block the vasoconstrictive [blood-vessel narrowing] effect of the A-beta protein
-- a critical protein involved in Alzheimer's disease ... These drugs appear to have anti-inflammatory properties, independent of their benefit in lowering cholesterol, that may help protect against dementia" - Note:
Red yeast rice is a non-prescription statin.
- Combining Statin With Estrogen May Maximise Post-Menopausal Cardiovascular Benefits - Doctor's Guide, 4/5/02 -
"Oral
estrogen alone increased the median level of C-reactive protein from 0.27 to 0.46 mg/dL, equivalent to a 70 percent rise. On the other hand, simvastatin decreased C-reactive protein levels from 0.29 to 0.28 mg/dL. Oral estrogen combined with simvastatin increased C-reactive protein
levels by 29 percent from 0.28 to 0.36 mg/dL" - Note: Red yeast rice is a non-prescription statin.
- Lipitor (Atorvastatin Calcium) Reduces C-Reactive Protein In Acute Coronary Syndrome - Doctor's Guide, 3/19/02
- Statins May Preserve Brain Power - WebMD, 3/18/02 -
"The study also found that statin use was associated with a lower risk of memory problems or dementia, regardless of total
cholesterol level. The authors say more research is needed to understand exactly how statins seem to protect the brain, but they suspect that the drugs may work by improving muscle function and reducing inflammation"
- Scientists Examine Long-Term Risks And Gains Of Painkillers - Intelihealth, 1/22/02 -
"The studies reflect scientists' growing interest in the idea that a
common condition, inflammation, may underlie many chronic and debilitating diseases - like Alzheimer's, heart disease, osteoporosis and diabetes - and that drugs that fight inflammation may have a role in preventing or delaying those diseases, or at least slowing them down ... Originally, the effect was attributed
to aspirin's ability to prevent blood clots, which can cause heart attacks or strokes. But now, researchers think part of the protective effect may come from aspirin's ability to quell inflammation in the arteries, helping to prevent blockages"
- Statin Treatment In Coronary Heart Disease Lowers Levels Of Marker C-Reactive Protein - Doctor's Guide, 11/29/01
- C-Reactive Protein Levels Indicative of Ischemic Risk in Some Men - Doctor's Guide, 11/12/01
- Studies Bolster Inflammation-Heart Disease Link; May Prove Better Predictor Than Cholesterol - Intelihealth, 11/6/01
- Inflammation May Contribute to Pre-eclampsia - Doctor's Guide, 10/3/01
- Insulin Produces Anti-Inflammatory Effect On Vessel Walls - Doctor's Guide, 8/9/01
- Another Study Suggests Inflammation May Trigger Diabetes - WebMD, 7/17/01 -
"The immune system and inflammation may be factors causing type 2 diabetes ... women who had high
levels of immune system substances called C-reactive protein or interleukin-6, or both, in their blood were more likely to develop type 2 diabetes ... Both C-reactive protein, called CRP, and interleukin-6, or IL-6, are considered indicators for inflammation"
- Cholesterol drug has wider benefit - USA Today, 6/28/01 - [in addition to lowering cholesterol]
"Cholesterol-lowering drugs, called statins,
apparently work by reducing levels of a chemical known as C-reactive protein. This protein causes inflammation, promotes blood clotting and weakens fat-encased blockages inside arteries, causing them to burst"
- Blood Test Could Indicate Who Might Benefit From Cholesterol-Lowering Drugs - Intelihealth, 6/27/01 -
"Half of all heart attack
patients have normal cholesterol levels. A blood test can detect high levels of C-reactive protein - a sign of inflammation"
- Brushing your teeth may be good for your ticker - Scientific America, 5/01 -
"Acute periodontitis may lead to heart disease because it might
cause low-level inflammation in the whole body: chemicals produced by the immune reaction in the gum pockets probably spill over into the bloodstream and trigger the liver to make proteins that inflame arterial walls and clot blood. Atherosclerosis and, ultimately, heart attack may result. One such factor,
C-reactive protein—a predictor of heart disease—is elevated in patients with periodontitis. Alternatively, the microbes themselves may travel from the mouth and affect blood vessels"
- Antibiotics Reduce Inflammation In Heart Disease, Effect On Heart Attacks Unproven - Doctor's Guide, 3/29/99
- New Agents May Provide Relief From Inflammation And Pain - Doctor's Guide, 3/4/98
- Alzheimer's Disease Directly Linked To Inflammation -- Animal Study - Doctor's Guide, 7/22/97
- Link Shown Between Inflammation and Heart Attack - Doctor's Guide, 4/2/97
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