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Recent Longevity News for the seven days ending 7/18/07.  You should consult your doctor if you are taking any medications.

Low vitamin D levels may increase metabolic syndrome risk - Nutra USA, 7/17/07 - "The most relevant finding in our study was the association of vitamin D concentrations with lipid levels. Our results are in concordance with the concept that vitamin D appears to be necessary to maintain adequate apolipoprotein A-I concentrations, the main component of HDL cholesterol" -  [Abstract] - See vitamin D at Amazon.com.

Curry Spice May Counter Alzheimer's - WebMD, 7/16/07 - "In preliminary lab tests, the chemical helped rid the blood of a key ingredient in Alzheimer's brain plaque"

Breast Cancer: More Veggies Not Better - WebMD, 7/17/07 - "eating more than five daily servings of fruits and vegetables doesn't offer extra benefit"

National Osteoporosis Foundation's Updated Recommendations for Calcium and Vitamin D3 Intake - Doctor's Guide, 7/16/07 - "adults aged 50 years and older should have 1200 mg of calcium/day and 800 to 1,000 I.U. of vitamin D3/day"

New Proof of Genistein's Efficacy and Safety for Osteopenia and Osteoporosis Published in Annals of Internal Medicine - Doctor's Guide, 7/16/07 - "85% of the women taking genistein showed a gain in bone density ... In addition, women taking genistein with calcium and vitamin D achieved a gain in bone density of approximately 3% per year over baseline and 6% per year over those taking the placebo"

Vitamin E: Friend or Foe During Radiation Therapy? - Physician's Weekly, 7/16/07 - "Not only did it show that vitamin E supplementation was of no benefit to patients, but it was also associated with a nearly 40% increased risk of death when compared to study counterparts who received a placebo. Vitamin E, despite what patients may think, appears to be much more harmful for patients who have head and neck cancer who are receiving radiation therapy" - Note:  Alpha tocopherol is the only one in the vitamin E family that is measured in IU, so that must have used alpha tocopherol in this study.  I had cancer of the tonsil that spread to a lymph node in the neck.  It was a stage III and they said my five years survival was 30% if I got surgery and radiation and that I was a goner if I refused the radiation.  Well I figured I was a goner anyway so I refused the radiation and thought that the surgery would buy me more time yet I still cancer free going on three years.  I took the mixed form of vitamin E the whole time.

Adult-Strength Aspirin Cuts Cancer Risk - Physician's Weekly, 7/16/07 - "Patients who had a daily intake of adult-strength aspirin (325 mg or more) for at least 5 years had a 15% lower overall risk of developing cancer. “Long-term daily aspirin use was associated with lower incidence of colorectal cancer (rate ratio = 0.68 among men and women combined) and prostate cancer (rate ratio = 0.81) and a non–statistically significant lower risk of female breast cancer (rate ratio =0.83)"

Grapefruit link to breast cancer - BBC News, 7/16/07 - "eating just a quarter of a grapefruit daily raised the risk by up to 30% ... The fruit is thought to boost levels of oestrogen - the hormone associated with a higher risk of the disease"

High-Sugar Foods May Affect Eyesight - WebMD, 7/13/07 - "People with the diets highest on the glycemic index were the most likely to have advanced AMD in at least one eye"

Drinking milk cuts diabetes risk - BBC News, 7/13/07 - "metabolic syndrome increased the risk of death by 50% ... men were 62% less likely to have the syndrome if they drank a pint or more of milk every day, and 56% less likely to have it if they regularly ate other dairy produce"

Mistletoe in Supportive Care for Colorectal and Pancreatic Cancers - Doctor's Guide, 7/12/07 - "Use of a fermented mistletoe extract (MEx; Iscador®) in long-term supportive care in hospitals and private practices demonstrated significant survival benefit and improvements in quality of life for patients with surgically treated primary, nonmetastatic colorectal carcinoma and for patients with all-stages pancreatic carcinoma, when combined with adjuvant chemotherapy and/or radiotherapy or passive aftercare in two multicentre, controlled, retrospective, epidemiological, observational, cohort studies"

Different omega-3 may offer different colorectal protection - Nutra USA, 7/11/07 - "Increased intake of EPA was associated with a 41 per cent reduction in risk, while DHA was associated with a 37 per cent reduction in risk, comparing highest against lowest average intakes" - [Abstract] - See Mega Twin EPA at Amazon.com.

Hormone Therapy Not for Older Women - WebMD, 7/11/07 - "Hormone therapy is a two-edged sword. It seems to help the earliest stages of heart disease, but may increase the risk of blood clots and arterial plaque rupture if continued into older age"

Meat, Sweets Boost Breast Cancer Risk - WebMD, 7/10/07 - "A meat-sweet diet raised the risk [of breast cancer] by 60% in postmenopausal women ... it would be prudent at the minimum to stay away from a diet heavy in meat, processed grains, sweets, and desserts"

Vitamin D Fights Colon Cancer - WebMD, 7/10/07 - "The findings support a number of previous studies that link vitamin D to colon cancer protection, to protection against breast and ovarian cancer, to protection against pancreatic cancer, and to overall reduction of cancer risk" - See vitamin D at Amazon.com.

Abstracts from this week's Doctor's Guide Nutrition/Dietetics plus abstracts from my RSS feeds:

Effects of an open-label pilot study with high-dose EPA/DHA concentrates on plasma phospholipids and behavior in children with attention deficit hyperactivity disorder - Nutr J. 2007 Jul 13;6(1):16 - "Nine children were initially supplemented with 16.2g EPA/DHA concentrates per day. The dosage was adjusted dependent on the ratio of arachidonic acid (AA) to EPA in the isolated plasma phospholipids at four weeks to reach a level normally found in the Japanese population ... A psychiatrist (blind to supplement compliance or dosage modifications) reported significant improvements in behavior (inattention, hyperactivity, oppositional/defiant behavior, and conduct disorder). There was also a significant correlation between the reduction in the AA:EPA ratio and global severity of illness scores" - See Mega Twin EPA at Amazon.com.

Vitamin D deficiency is associated with the metabolic syndrome in morbid obesity - Clin Nutr. 2007 Jul 9 - "Vitamin D deficiency is associated with the metabolic syndrome in morbidly obese patients"

Prevalence of vitamin D inadequacy in European postmenopausal women - Curr Med Res Opin. 2007 Jul 12 - "In the whole study population, the prevalence of 25(OH)D inadequacy was 79.6% and 32.1% when considering cut-offs of 80 and 50 nmol/L, respectively and when considering patients aged less than 65 years, the prevalence reached 86% (cut-off of 80 nmol/L) and 45% (cut-off of 50 nmol/L)"

Exposure to traffic emissions throughout life and risk of breast cancer: the Western New York Exposures and Breast Cancer (WEB) study - Cancer Causes Control. 2007 Jul 14 - "Higher exposure to traffic emissions at the time of menarche was associated with increased risk of premenopausal breast cancer (OR 2.05, 95% CI 0.92-4.54, p for trend 0.03); and at the time of a woman's first birth for postmenopausal breast cancer (OR 2.57"

A Nested Case-Control Study of Plasma 25-Hydroxyvitamin D Concentrations and Risk of Colorectal Cancer - J Natl Cancer Inst. 2007 Jul 10 - "we observed a non-statistically significant inverse association between higher plasma 25(OH)D concentration and risk of colorectal cancer and a statistically significant inverse association for colon cancer (highest versus lowest quintile: odds ratio [OR] = 0.46, 95% confidence interval [CI] = 0.24 to 0.89; P(trend) = .005). After pooling the results from the HPFS and NHS, higher plasma 25(OH)D concentrations were statistically significantly associated with decreased risks of both colorectal cancer (highest versus lowest quintile, OR = 0.66, 95% CI = 0.42 to 1.05; P(trend) = .01) and colon cancer (highest versus lowest quintile, OR = 0.54" - See vitamin D at Amazon.com.

Effects of milk supplementation with conjugated linoleic acid (isomers cis-9, trans-11 and trans-10, cis-12) on body composition and metabolic syndrome components - Br J Nutr. 2007 Jul 11;:1-8 - "Subjects were randomised to a daily intake of 500 ml milk supplemented with 3 g CLA (using a mixture of the bioactive isomers cis-9, trans-11 and trans-10, cis-12, marketed as Tonalin(R), Naturlinea; Central Lechera Asturiana) or placebo for 12 weeks ... The supplementation of milk with 3 g CLA over 12 weeks results in a significant reduction of fat mass in overweight but not in obese subjects. CLA supplementation was not associated with any adverse effects or biological changes" - See conjugated linoleic acid at Amazon.com.

Rosiglitazone reduces office and diastolic ambulatory blood pressure following 1-year treatment in non-diabetic subjects with insulin resistance - Blood Press. 2007;16(2):95-100 - "After 1 year, the office BP decreased by -3.1 mmHg systolic (p<0.05) and -3.8 mmHg diastolic (p<0.001) in the RSG group versus placebo"

Dietary Fatty acids and colorectal cancer: a case-control study - Am J Epidemiol. 2007 Jul 15;166(2):181-95 - "Significant dose-dependent reductions in risk were associated with increased consumption of omega-3 polyunsaturated fatty acids (highest vs. lowest quartile of intake: odds ratio = 0.63, 95% confidence interval: 0.50, 0.80; p < 0.0005 for trend) and of eicosapentaenoic (odds ratio = 0.59, 95% confidence interval: 0.47, 0.75; p < 0.0005 for trend) and docosahexaenoic (odds ratio = 0.63" - See Mega Twinlab Mega Twin EPA at Amazon.com.

Selective Vitamin Supplementation May Improve Cognitive Functions - Clinical Psychiatry News, 6/07 - "Supplementation with vitamins B6 and B12 and folate in younger to middle-aged adults improves motor speed and sequencing ability on neuropsychological tests ... participants who took the supplements performed the task significantly faster than they had a month before, which indicated increased motor speed. The placebo group patients had no improvement on this test ... Among people who entered the trial with vitamin B12 levels on the low end of the normal range, those who received supplementation significantly improved their performance on the Trail Making Test Parts A and B. Part B includes some assessment of executive function"

I joined an affiliate program with MyFax.com.  I joined it myself.  It is only $10 per month with no signup fee or a little over $9 per month if you pay by the year.  It would cost you more than twice that for a dedicated number for your fax machine.  You are offered the choice of an 800 number or local number.  The advantage of a local number is that you can receive international faxes.

Supplement Focus (omega-3):

  1. Omega-3 Fatty Acids in the Management of Hypertriglyceridemia: New Findings and Formulations - Continuing Medical Education (CME):Princeton Media Associates, exp. 10/29/06 - "To lower TG levels, the dose of omega-3 therapy is ~4 g of EPA + DHA per day"
  2. Omega-3 Fatty Acids: Recommendations for Therapeutics and Prevention - Medscape, exp. 10/19/06 - "Studies support low DHA as a risk factor for dementia. Low total n-3 fatty acids levels, EPA and DHA associate with greater risk of CVD, dietary intake and/or supplementation is supported as a secondary or tertiary prevention measure. Omega-3 fatty acids also help to prevent type 2 diabetes and the metabolic syndrome, two common precursors to CVD. There is some support for schizophrenia, depressive or aggressive disorders; however, large multi-center clinical trials have yet to be conducted. The anti-inflammatory properties of n-3 fatty acids are helpful in decreasing symptoms of rheumatoid arthritis and may possibly increase remission length in Crohn's patients"
  3. Omega 3: Implications in human health and disease - PowerPak (CME course), exp. 8/1/03 - "On average, our society consumes around 35% of its caloric intake from fat, mainly as vegetable oil. The omega 6 LA comprises 7% to 9% of our daily caloric intake, while the omega 3 LNA makes up about 0.7% of energy. It is therefore estimated that the dietary ratio of LA to LNA ranges from 10 to 20:1, at which level the metabolism of LNA is strongly suppressed.2,25 Again, this is far more than the recommended ratio of 2.3:1"
  4. An Evidence-Based Me dicine Approach to the Appropriate Selection of Supplementation with Omega-3 Fatty - PowerPak.com, 6/1/07 - "Fish oils EPA and DHA appear to result in different physiologic effects than their precursor, the plant-derived ALA.12-14 Biosynthesis of EPA or DHA from ALA is limited. Although dietary consumption of ALA alone will prevent EFA deficiency, emerging scientific evidence indicates that for optimum health or body function, the fish oils EPA and DHA should also be ingested regularly, either from dietary or supplement sources. Use of ALA supplementation alone, even with high dose or long-term consumption, does not result in lowered triglyceride concentrations seen with EPA or DHA, nor does it demonstrate similar in vitro susceptibility to oxidation of LDL cholesterol"
  5. The Heart-Healthy Benifits of Omega-3 Fatty Acids - John Hopkins University School of Medicine, 6/05 - "Fish-oil supplements appear to have much lower levels of toxins than fish. In a study of 5 over the-counter fish-oil preparations, levels of PCBs and organochlorines were below the detectable limit in all of the supplements ... Because consumption of this amount of fish in secondary prevention is difficult for most individuals, dietary supplementation is generally needed and should be recommended. The dose in secondary prevention should be at least 875 mg of EPA + DHA per day. This dose can generally be obtained by taking 2 capsules of concentrated fish oils (at least 50% EPA + DHA) per day. For example, such a preparation would contain 500 mg of EPA + DHA per each 1000-mg fish-oil capsule"
  6. Omega 3: Implications in Human Health and Disease - PowerPak.com - "It should be noted, however, that flaxseed or flaxseed oil does not contain EPA or DHA. Thus flaxseed and fish oil are not interchangeable sources of omega 3 fatty acids per se"
  7. Can Blindness Be Prevented Through Diet? - Science Daily, 6/24/07 - "Increasing intake of the omega-3 fatty acids DHA and EPA, found in popular fish-oil supplements, may protect against blindness resulting from abnormal blood vessel growth in the eye ... Mice on the omega-3 diet, rich in DHA (docosahexaenoic acid) and its precursor EPA (eicosapentaenoic acid), had less initial vessel loss in the retina than the omega-6-fed mice: the area with vessel loss was 40 to 50 percent smaller"
  8. Omega-3 Fatty Acids May Lower Genetic Risk for Prostate Cancer - Medscape, 6/21/07 - "Overall, diets rich in omega-3 fatty acids reduced prostate tumor growth, slowed histopathological progression, and increased survival, the researchers write. The 12-month survival rate was 60% for mice fed a diet high in omega-3, 10% on the low–omega-3 diet, and 0% on the high–omega-6 diet. The ideal ratio of omega-6 to omega-3 fatty acids is 1:1, and mice fed diets with this ratio of fatty acids were able to delay both the formation and progression of prostate tumors and prolong their survival"
  9. Omega-3s May Lower Blood Pressure - WebMD, 6/4/07 - "Participants with the highest intake of omega-3 fatty acids tended to have the lowest blood pressure"
  10. Higher Intake Of Fish And Vitamin D Levels Linked To Lower Risk Of Age-related Macular Disease - Science Daily, 5/14/07 - "Individuals who have higher dietary intake of foods with omega-3 fatty acids and higher fish consumption have a reduced risk of advanced age-related macular degeneration, while those with higher serum levels of vitamin D may have a reduced risk of the early stages of the disease"
  11. Marine Omega-3 Fatty Acids Have Positive Effect On Muscle Mass, Study Shows - Science Daily, 5/9/07 - "In mammals, the ability to use nutrients from food and convert them into muscle proteins decreases with age. Though the exact cause of this phenomenon is still unclear, insulin resistance of aging muscle cells has been suggested as a possible answer ... omega-3 fatty acids are known to improve glucose metabolism in people and animals showing insulin resistance ... After five weeks, animals with the marine omega-3 diet showed increased sensitivity to insulin which, in turn, improved protein metabolism"
  12. Preventing Breast Cancer? - Dr. Weil, 5/3/07 - "Take 2 grams of fish oil a day. High omega-3 fatty acid intake significantly reduces your risk of breast cancer"
  13. Supplement 'boosts' brain power - BBC News, 3/12/07 - "they were given two capsules a day of the VegEPA supplement, which contains an omega-3 fatty acid called EPA ... Tests done at the end of the three-month study found the children showed an increase in reading age of well over a year, their handwriting became neater and more accurate and they paid more attention in class ... In three months you might expect to see a small NAA increase ... But we saw as much growth as you would normally see in three years"
  14. Omega-3 in fish oils might ease depression - USA Today, 3/6/07 - "The more DHA a person consumed, the more gray matter there was in three areas of the brain linked to mood: the amygdala, the hippocampus and the cingulate, Conklin says. Seriously depressed people tend to have less gray matter in these areas" [WebMD]
  15. Fish Oil for Moms May Benefit Babies - WebMD, 12/21/06 - "children of mothers who took fish oil supplements scored significantly higher on tests of hand-eye coordination than those who took olive oil supplements"
  16. More support omega-3 may protect against colorectal cancer - Nutra USA, 11/22/06 - "A diet rich in omega-3 polyunsaturated fatty acids (PUFAs) could reduce the risk of colorectal cancer by 85 per cent"
  17. Omega-3 Fatty Acids May Slow Cognitive Decline In Some Patients With Very Mild Alzheimer's Disease - Science Daily, 10/11/06 - "For six months, 89 patients (51 women and 38 men) took 1.7 grams of docosahexaenoic acid (DHA) and .6 grams of eicosapentaenoic acid (EPA), while 85 patients (39 women and 46 men) took placebo ... among a subgroup of 32 patients with very mild cognitive impairment at the beginning of the study, those who took the fatty acids experienced less decline in six months compared with those who took placebo"
  18. New Study Finds Omega-3's in Fatty Fish Can Reduce Risk of Cancer - Doctor's Guide, 9/26/06 - "At least one portion of fatty fish a week during the period (1987-2004) reduced the risk of renal cancer by 74 per cent compared with those who never ate fatty fish"
  19. Protection for Aging Eyes - New Hope Natural Media Online, 8/31/06 - "A 40% reduction in the incidence of early age-related macular degeneration was associated with eating fish at least once a week; eating fish at least three times per week even reduced the incidence of late-stage age-related macular degeneration"
  20. Altering Fatty Acid Levels In Diet May Reduce Prostate Cancer Growth Rate - Science Daily, 8/1/06 - "tumor cell growth rates decreased by 22 percent and PSA levels were 77 percent lower in the group receiving a healthier balance of fatty acids compared with the group that received predominantly omega-6 fatty acids"
  21. Fish Oil May Help Save Your Eyes - WebMD, 7/10/06 - "men with the highest fish consumption (at least two weekly servings) were 45% less likely to have AMD than those with the lowest fish consumption (less than one weekly serving)"
  22. A Safer Alternative to NSAIDs? - Physician's Weekly, 7/3/06 - "omega-3 essential fatty acid (EFA) may be as effective as nonsteroidal anti-inflammatory drugs (NSAIDs) in relieving neck and lower back pain without the risk of harmful complications"
  23. Omega-3s may help depressive kids - pilot study - Nutra USA, 6/23/06 - "seven out of ten children in the omega-3 group and none of the children in the placebo group had depression score reductions of 50 per cent or more"
  24. Hypertriglyceridemia - Medscape, 6/1/06 - "Omega-3 fatty acids (4 g per day) will reduce triglyceride levels by 30%"
  25. Fish Oil May Help Ease Back Pain - WebMD, 4/6/06 - "88% of patients said they would keep taking fish oil supplements"
  26. In a Bad Mood? Eat Your Fish - WebMD, 3/3/06 - "People in our study who had low blood levels of omega-3 fatty acids were more likely to report mild to moderate symptoms of depression, more moodiness, and more impulsivity ... people with higher blood levels of omega-3s were found to be more agreeable"
  27. Oily fish makes 'babies brainier' - BBC News, 1/20/06 - "mothers with the lowest intake of the essential fatty acid had children with a verbal IQ six points lower than the average ... Low intake of the crucial fatty acid also appeared to lead to more problems of social interactions - such as an inability to make friends"
  28. Fatty Acids May Protect against Cardiovascular Disease - Doctor's Guide, 11/21/05 - "After 4.5 years of follow-up, patients taking EPA were 19% less likely to have adverse coronary events compared to controls"
  29. Eating Fish Associated with Slower Cognitive Decline - Doctor's Guide, 10/12/05 - "Consuming fish at least once a week was associated with a 10% per year slower rate of cognitive decline in elderly people ... consumption of one omega-3 fatty acid in particular, docosahexaenoic acid (DHA), is important for memory performance in aged animals"
  30. Omega-3, Omega-6 Fatty Acids Can Affect Bone Loss - CBS 2 Chicago, 7/12/05 - "eating foods rich in omega-3 fatty acids -- found in walnuts and salmon -- may prevent bone thinning. While excess amounts of omega-6 -- found in grains and beef -- may actually promote bone loss ... a low ratio of omega-6 to omega-3 appears to be best"
  31. Fish Help the Heart by Fighting Inflammation - WebMD, 7/5/05 - "compared with those who said they didn't eat fish, those who ate at least 10.5 ounces of fish per week had 33% lower C-reactive protein and 33% lower tumor necrosis factor-alpha (another indicator of inflammation) levels as well as much lower levels of other signs of inflammation"
  32. Omega-3 Offers Hope For New Anti-breast Cancer Drugs - Science Daily, 6/8/05 - "Compounds of Omega-3 fatty acids and propofol reduce the ability of breast cancer cells to develop into malignant tumours, inhibiting cancer cell migration by 50% and significantly reducing their metastatic activity ... Propofol is a potent anti-oxidant known to inhibit cancer cell migration by only 5-10%"
  33. Omega-3 Fatty Acids and Depression - Clinical Psychiatry News, 5/05 - "English investigators conducted a 12-week, double-blind, placebo-controlled trial evaluating the efficacy of EPA doses of 1,000, 2,000, or 4,000 mg/day in addition to unchanged standard treatment in 70 patients with persistent depression. The 1,000-mg group showed a significant decrease in depression as compared with placebo, but the other groups showed little evidence of efficacy ... The bulk of evidence suggests that omega-3 fatty acid supplementation is effective in treating depression in patients with low omega-3 diets"
  34. Breast Cancer Protection Starts in the Womb - WebMD, 4/20/05 - "Mothers who choose foods packed with omega-3 fatty acids during pregnancy and while nursing and then feed their kids such a diet after weaning may reduce the risk of breast cancer in their daughters by nearly 90%, early research in mice indicates"
  35. High-Dose Omega-3 Oils Used to Treat Non-Surgical Neck and Back Pain - Doctor's Guide, 4/20/05 - "this could be the answer to the adverse effects seen with nonsteroidal anti-inflammatory drugs (NSAIDs), including cyclooxygenase (COX)-2 inhibitors, which have been associated with potentially catastrophic adverse effects ... 88% percent said they were pleased enough with the outcomes that they planned to continue using the fish oils"
  36. Fish Oil May Fight Alzheimer's Disease - WebMD, 3/22/05 - "Brain imaging showed that the high-DHA diet cut brain plaque by 40%. The largest drops were seen in brain areas vulnerable to Alzheimer's disease ... The high-DHA diet also delivered the biggest drop (70%) in levels of beta-amyloid protein in the brain, a building block of plaque"
  37. Oily fish helps cut inflammation - BBC News, 3/13/05 - "We always suggest that people with arthritis eat two or three portions of oily fish a week, or take 1,500mg fish oil capsules a day"
  38. Arthritis Patients Can Seek Natural Pain Relief - CBS Chicago, 1/15/05 - "They placed 120 patients on fish oil supplements. About 59 percent of reported decreased joint pain, and 68 percent were able to discontinue prescription drugs entirely"
  39. Fish oil supplements slow ageing of brain - Nutra USA, 12/21/04 - "People who eat oily fish or take fish oil supplements score 13 per cent higher in IQ tests and are less likely to show early signs of Alzheimer’s disease ... The brains of fish oil users seemed to be faster. There was a strong relationship between mental test scores and the omega-3 content in the blood"
  40. Omega-3 Fatty Acids: Good For The Heart, And (maybe) Good For The Brain - Science Daily, 11/8/04 - "There is mounting evidence that a diet containing omega-3 fatty acids, already known to help prevent cardiovascular disease, may also prevent depression"
  41. ConsumerLab.com - Omega-3 Fatty Acids (EPA and DHA) from Fish/Marine Oils review - ConsumerLab.com, 10/6/04 - "None of the products were found to contain detectable levels of mercury ... none of the products contained unsafe levels of PCBs ... none of these supplements contained unsafe levels of dioxins"
  42. Fish Once a Week Cuts Alzheimer's Risk - WebMD, 7/21/03 - "Weekly fish eaters had a 60% lower risk of Alzheimer's than people who rarely or never ate fish ... The beneficial effects of [fatty acids] from fish may be counterbalanced by toxins ... A high antioxidant/low saturated fat diet pattern with a greater amount of fish, chicken, fruits, and vegetables and less red meat and dairy products is likely to lower the risk of AD, as well as that for heart disease and stroke ... Furthermore, B vitamin supplements, containing vitamins B12 and B6 and folic acid, lower plasma total homocysteine levels, possibly decreasing the risk of stroke, heart disease and perhaps Alzheimer's disease"
  43. Dietary Omega-3 Fatty Acids May Reduce Risk of AMD - Medscape, 5/6/03 - "Dietary omega-3 fatty acids but not beta-carotene supplementation is associated with a reduced risk of age-related macular degeneration (AMD) ... omega-3 fatty acids may also reduce the risk of dry eye syndrome in women"
  44. Eating Fish Lowers Heart Disease Risk in Women With Diabetes - WebMD, 3/31/03 - "Women with type 2 diabetes who ate fish once a week were 40% less likely to develop heart disease than those who rarely ate it, and eating fish almost every day was associated with a two-thirds reduction in risk ... It is believed that omega-3 fatty acids abundant in the fat of many fish reduces the risk of heart disease by lowering triglyceride levels, improving blood vessel function, and reducing blood-clot formation"
  45. Fish Oil Eases Depression - WebMD, 10/18/02 - "people who added a daily dose of omega-3 fatty acids to their regular antidepressant treatment had significant improvement in symptoms, including anxiety, sleeping problems, sadness, decreased sexual desire, and suicidal tendencies ... Previous studies have suggested that depressed people have lower-than-normal levels of a fatty acid known as EPA (eicosapentaenoic acid), which plays an important role in maintaining normal brain function"
  46. EPA Useful Add-on Therapy in Schizophrenia - Medscape, 9/9/02 - "After 12 weeks of treatment, the EPA group had significantly greater reduction of Positive and Negative Syndrome Scale total scores and of dyskinesia scores than the placebo group ... We regard these results as remarkable, considering the refractory nature of schizophrenia in the subjects"
  47. Omega-3 Fatty Acids May Prevent Heart Disease By Improving Arterial Elasticity - Intelihealth, 7/25/02 - "The research focused on the effects of two forms of omega-3 fatty acid--eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)--on systemic arterial compliance, a measure of the degree of large artery elasticity. Increased stiffness in the large arteries can lead to systolic hypertension and increased pulse pressure (the difference between diastolic and systolic pressure), both factors that may contribute to increased coronary risk. Thirty-eight middle-aged men and women with elevated plasma total cholesterol consumed an EPA supplement, a DHA supplement, or a placebo during a 7-week dietary intervention. In contrast to the placebo group who showed no change, systemic arterial compliance rose 36% in the EPA group and 27% in the DHA group, while there was a trend toward reduced systolic and pulse pressure. Both omega-3 fatty acid supplement groups experienced significant declines in plasma total triacylglycerol concentrations"
  48. See Mega Twin EPA at Amazon.com or Vitacosticon. - This is my first pick.  Don't be fooled by cheap fish oil capsules.  Omega-3 is the sum of the sum of the eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaenoic acids (DHA), not the total fish oil that it says on the label.  Ref. x

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