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Fibromyalgia Syndrome

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• Comparison between Acupuncture and Nutraceutical Treatment with Migratens® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial - Nutrients. 2020 Mar 19 - "Fibromyalgia syndrome (FMS) ... A total of 60 FMS female patients were randomized for treatment with a nutritional combination containing coenzyme Q10, vitamin D, alpha-lipoic acid, magnesium, and tryptophan (Migratens® Group) or acupuncture treatment (Acupuncture Group) performed according the principles of traditional Chinese medicine (TCM), both for 3 months. Changes in pain and in quality of life (QoL) measured with a Fibromyalgia Impact Questionnaire Score-Revised (FIQ-R) and the Fibromyalgia Severity Scale (FSS) were performed at 1, 3, and 6 months after the start of treatments ... Migratens® treatment shows a statistically significant reduction of pain 1 month after the start of therapy (T1, p = 0.025), strengthened after 3 months with maintenance of treatment (p = 0.012). The efficacy in reducing pain was apparent in the Acupuncture Group at all post-treatment determinations and at follow-up (T1 and T2 p = <0.001). Regarding QoL, improvement in FIQ-R and FSS values was revealed in both groups ... The nutraceutical approach with Migratens® seems to be an effective option to for patients with FMS. Our experience confirmed also the validity of acupuncture in these patients. Considering the complexity of the management of FMS patients, our results suggest a cyclical and sequential, or even concurrent treatment with different approaches, to improve the efficacy and the compliance of patients to long-term treatment"
• 'First Evidence' Links Gut Bacteria, Fibromyalgia - Medscape, 7/9/19 - "women with fibromyalgia had significant differences in 19 species of gut bacteria compared with healthy controls. They also had higher serum levels of butyrate and lower levels of propionate ... Evidence is mounting on the critical role of the gut microbiota in a variety of pathologies, including, but not limited to, metabolic, cardiovascular, oncologic, neurologic, and psychiatric disorders" - See probiotic products at Amazon.com.
• Altered microbiome composition in individuals with fibromyalgia - Pain. 2019 Jun 18 - "When comparing FM patients to unrelated controls using differential abundance analysis, significant differences were revealed in several bacterial taxa. Variance in the composition of the microbiomes was explained by FM-related variables more than by any other innate or environmental variable and correlated with clinical indices of FM. In line with observed alteration in butyrate metabolising species, targeted serum metabolite analysis verified differences in the serum levels of butyrate and propionate in FM patients. Using machine learning algorithms, the microbiome composition alone allowed for the classification of patients and controls (ROC AUC 87.8%)" - [Nutra USA] - See probiotic products at Amazon.com.
• Gut bacteria associated with chronic pain for first time - Science Daily, 6/20/19 - "We also saw that the severity of a patient's symptoms was directly correlated with an increased presence or a more pronounced absence of certain bacteria -- something which has never been reported before ... At this point, it's not clear whether the changes in gut bacteria seen in patients with fibromyalgia are simply markers of the disease or whether they play a role in causing it" - See probiotic products at Amazon.com.
• Vitamin D supplements reduce pain in fibromyalgia sufferers - Science Daily, 1/17/14 - "30 women with FMS with low serum calcifediol levels (below 32ng/ml) were randomized to a treatment or control group. The goal for the treatment group was to achieve serum calcifediol levels between 32 and 48ng/ml for 20 weeks via oral cholecalciferol supplements ... Twenty-four weeks after supplementation was stopped, a marked reduction in the level of perceived pain occurred in the treatment group. Between the first and the 25th week on supplementation, the treatment group improved significantly on a scale of physical role functioning, while the placebo group remained unchanged. The treatment group also scored significantly better on a Fibromalgia Impact Questionnaire (FIQ) on the question of "morning fatigue."" - See vitamin D at Amazon.com.
• Fibromyalgia symptoms improved by lifestyle adjustments - Science Daily, 3/29/10
• Association between serum ferritin level and fibromyalgia syndrome - Eur J Clin Nutr. 2010 Jan 20 - "The mean serum ferritin levels in the fibromyalgia (FM) and control groups were 27.3+/-20.9 and 43.8+/-30.8 ng/ml, respectively, and the difference was statistically significant ...having a serum ferritin level <50 ng/ml caused a 6.5-fold increased risk for FMS" - See Feosol Ferrous Sulfate Iron Supplement Therapy, Tablets - 125 ea (Pack of 2) at Amazon.com.
• Treating Chronic Fatigue and Fibromyalgia? - Dr. Weil, 8/17/09
• Inadequate Vitamin D Levels Linked To High Use Of Narcotic Medication By Patients In Chronic Pain - Science Daily, 3/20/09 - "Mayo Clinic research shows a correlation between inadequate vitamin D levels and the amount of narcotic medication taken by patients who have chronic pain ... Physicians who care for patients with chronic, diffuse pain that seems musculoskeletal — and involves many areas of tenderness to palpation — should strongly consider checking a vitamin D level ... many patients who have been labeled with fibromyalgia are, in fact, suffering from symptomatic vitamin D inadequacy" - See vitamin D at Amazon.com.
• Treating Chronic Fatigue and Fibromyalgia? - Dr. Weil, 1/13/09
• The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study - J Altern Complement Med. 2006 Nov;12(9):857-62 - "D-ribose significantly reduced clinical symptoms in patients suffering from fibromyalgia and chronic fatigue syndrome" - See D-ribose at Amazon.com.
• Acupuncture Helps Fibromyalgia - WebMD, 8/24/05
• DHEA no help for fibromyalgia - Nutra USA, 8/8/05
• Benefit of Ribose in a Patient With Fibromyalgia - Medscape, 1/7/05 - "Ribose is a naturally occurring carbohydrate with documented medical benefits in patients with cardiovascular disease. To our knowledge, this is the first report to suggest its potential benefit in a patient with fibromyalgia, who had had suboptimal results with conventional therapies"
• Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis - Am J Clin Nutr. 2004 Mar;79(3):362-71 - "Vitamin D deficiency is often misdiagnosed as fibromyalgia ... Studies in both human and animal models add strength to the hypothesis that the unrecognized epidemic of vitamin D deficiency worldwide is a contributing factor of many chronic debilitating diseases ... The recommended adequate intakes for vitamin D are inadequate, and, in the absence of exposure to sunlight, a minimum of 1000 IU vitamin D/d is required to maintain a healthy concentration of 25(OH)D in the blood" - See vitamin D at Amazon.com.
• Individualized Homeopathy Helps Fibromyalgia Sufferers - Healthwell Exchange Daily News, 2/26/04
• Increased Free Radical Levels May Cause Fibromyalgia - Doctor's Guide, 1/7/04 - "These data suggest, claim the authors, that the "oxidant/antioxidant imbalance related to the disease process, and the increase in free radical levels may be responsible for the development of fibromyalgia.""
• Mild Exercise Effective for Fibromyalgia - New Hope Natural Media, 9/5/02
• Exercise Helps In Fibromyalgia Despite Initial Pain - Doctor's Guide, 7/25/02
• Exercise Can Ease Fibromyalgia - WebMD, 7/25/02
• Massage Helps Fibromyalgia - WebMD, 5/9/02
• Intensifying Aerobics Does Not Provide Big Improvement In Fibromyalgia - Doctor's Guide, 3/11/02
• Living Food Diet Eases Fibromyalgia - Nutrition Science News, 3/01 - "A low-salt, uncooked vegan diet of "living food" relieves fibromyalgia symptoms ... Despite its benefits, none of the patients chose to adhere to the diet beyond the study period. They did report, however, that their pain gradually returned as they drifted back to their previous omnivorous diet"
• She's Back! A woman reclaims her life after battling fibromyalgia - Life Extension Magazine, 12/99
• Persistent Pain - Nutrition Science News, 10/99

Other News:

• Drugs to Treat Fibromyalgia Just as Likely to Harm as Help, Review Finds - Science Daily, 2/20/13
• High rate of restless legs syndrome found in adults with fibromyalgia - Science Daily, 10/15/10
• Obesity associated with increased risk of fibromyalgia - Science Daily, 4/29/10
• Fibromyalgia affects mental health of those diagnosed and their spouses, study finds - Science Daily, 4/28/10
• Inexpensive Drug Appears To Relieve Fibromyalgia Pain - Science Daily, 4/17/09
• FDA Approves Milnacipran for Fibromyalgia - Medscape, 1/15/09
• Antidepressants Help Treat Fibromyalgia - WebMD, 1/13/09
• Newly Approved Fibromyalgia Treatment - Physician's Weekly Article, 9/15/08
• Cymbalta Approved for Fibromyalgia - Medscape, 6/20/08
• Fibromyalgia: The Invisible Disease - Science Daily, 5/13/08
• Growth Hormone Therapy May Benefit Some Fibromyalgia Patients - Medscape, 12/14/07
• Pooled Analysis Confirms Efficacy of Pregabalin for Fibromyalgia Pain - Doctor's Guide, 11/13/07
• Exercise And Education Helps Women With Fibromyalgia - Science Daily, 11/13/07
• Pregabalin Therapy for Fibromyalgia Eases Pain and Improves Sleep Patterns - Doctor's Guide, 10/9/07
• Why Don't Painkillers Work For People With Fibromyalgia? - Science Daily, 9/27/07
• Further Legitimization Of Fibromyalgia As A True Medical Condition - Science Daily, 6/25/07
• FDA Approves First Drug for Treating Fibromyalgia - Doctor's Guide, 6/21/07
• Gabapentin Shown Effective For Fibromyalgia Pain - Science Daily, 6/11/07
• Fibromyalgia: The Misunderstood Disease - Science Daily, 6/1/07
• Lyrica May Help Ease Fibromyalgia Pain - WebMD, 5/23/07
• Fibromyalgia Patients More Sensitive? - WebMD, 5/14/07
• Lyrica May Relieve Fibromyalgia Pain - WebMD, 11/14/06
• Pramipexole May Decrease Fibromyalgia Symptoms - Medscape, 7/28/06
• Sodium Oxybate May Reduce Fibromyalgia Pain - Doctor's Guide, 2/24/06
• Shedding Weight Aids Fibromyalgia - Clinical Psychiatry News, 2/06
• Drug Used To Treat Parkinson's Disease May Be Beneficial In Treating Fibromyalgia - Science Daily, 7/28/05
• Duloxetine (Cymbalta) Effective for Women With Fibromyalgia, With or Without Comorbid Depression - Doctor's Guide, 5/30/05
• Study of Brain Activity of Fibromyalgia Patients Supports Treating Depression and Physical Pain Independently, Even When They Co-Exist - Doctor's Guide, 4/28/05
• Pregabalin Cuts Pain in Tough-To-Treat Patients With Neuropathic Pain and Fibromyalgia Syndrome - Doctor's Guide, 4/13/05
• Fibromyalgia Pain Responds to Pramipexole - Clinical Psychiatry News, 2/05
• Being Active Won't Worsen Fibromyalgia - WebMD, 1/26/05
• Most Fibromyalgia Patients Turn to Alternative Medicine - Clinical Psychiatry News, 11/04
• Paroxetine Controlled Release May Relieve Fibromyalgia Symptoms - Medscape, 10/12/04
• Help for Breastfeeding Moms With Fibromyalgia - WebMD, 9/23/04
• Study Finds Fibromyalgia Prohibits Sufferers From Breast-feeding - Science Daily, 9/23/04
• Study Finds Patients With Fibromyalgia Have Difficulty Breast-Feeding - Doctor's Guide, 9/21/04
• Duloxetine Effective in Fibromyalgia - Medscape, 9/10/04
• Antidepressant Duloxetine Aids in Improving Symptoms, Relieving Pain in Fibromyalgia - Doctor's Guide, 9/9/04
• Pregabalin Could Be Next Step in Fibromyalgia Tx - Clinical Psychiatry News, 9/04
• Watch for Headache in Fibromyalgia - Clinical Psychiatry News, 8/04
• Acupuncture May Aid Some With Fibromyalgia - Clinical Psychiatry News, 8/04
• Cyclic Alternating Pattern Correlated to Severity of Symptoms in Fibromyalgia - Doctor's Guide, 6/11/04
• Posttraumatic Stress, Fibromyalgia Linked - WebMD, 6/10/04
• Duloxetine Benefits Women With Fibromyalgia - Clinical Psychiatry News, 6/04
• Fibromyalgia Patients May Respond Well to an Interdisciplinary Approach - Doctor's Guide, 3/9/04
• Duloxetine May Be Effective for Treatment of Fibromyalgia Symptoms - Doctor's Guide, 3/5/04
• Fibromyalgia Isn't Depression - WebMD, 10/24/03
• Fibromyalgia Comes in 3 Shapes and Sizes - WebMD, 10/3/03
• Ropinirole May Resolve Refractory Fibromyalgia - Clinical Psychiatry News, 5/03
• Central Nociceptive Hyperexcitability Important in Fibromyalgia - Medscape, 5/1/03
• Fibromyalgia Patients Feel Pain More Acutely - WebMD, 4/30/03
• Fibromyalgia's Musculoskeletal Pain May Ease With Pregabalin Therapy - Clinical Psychiatry News, 3/03
• Doctors Over-Diagnose Fibromyalgia, Miss Other Rheumatological Ills - Doctor's Guide, 3/7/03
• Improving Examination for Fibromyalgia of Intervertebral Disc Origin - Doctor's Guide, 2/24/03
• Citalopram Shows Promise in Treating Symptoms of Fibromyalgia - Doctor's Guide, 2/21/03
• Standard Fibromyalgia Care Often Has Favourable Outcome - Doctor's Guide, 2/20/03
• Fibromyalgia More Than Growing Pains - TheSanDiegoChannel.com, 2/6/03
• Lifting the Veil - The Face of Fibromyalgia - Physician's Weekly, 1/30/03
• Sleep Mediates Pain and Fatigue in Fibromyalgia - Doctor's Guide, 12/17/02
• Fibromyalgia Overtreatment Can Be Toxic - Clinical Psychiatry News, 12/02
• Pregabalin Effective in Treating Symptoms of Fibromyalgia - Doctor's Guide, 10/30/02
• Pregabalin Improves Pain and Fatigue Symptoms in Patients With Fibromyalgia - Medscape, 10/30/02
• Lower-Back and Fibromyalgia Pain Linked, Possible Source Identified - Doctor's Guide, 10/28/02
• Laser Therapy And Amitriptyline Both Effective For Fibromyalgia - Doctor's Guide, 10/24/02
• Women with Fibromyalgia Experience Significant Pain During Routine Mammography - Doctor's Guide, 8/22/02
• Fibromyalgia Patients Benefit From Balneotherapy - Doctor's Guide, 8/1/02
• Growth Hormone Eases Fibromyalgia Pain - WebMD, 6/27/02
• Fibromyalgia Responds to Growth Hormone Treatment - Doctor's Guide, 6/20/02 - "Patients with fibromyalgia get relief from many of their symptoms when they are treated with growth hormone therapy ... We had previously found that a high number of patients with fibromyalgia have low levels of insulin-like growth factor-1 [IGF-1] ... The results suggest that a secondary growth hormone deficiency may be responsible for some symptoms of fibromyalgia"
• Fibromyalgia Pain Is Real - WebMD, 6/12/02
• Fibromyalgia Pain Isn't All In Patients' Heads, New Brain Study Finds - Doctor's Guide, 6/6/02
• Women With Fibromyalgia Have Impaired Growth Hormone Secretion - Doctor's Guide, 5/22/02
• GH Response to Exercise Impaired in Fibromyalgia - Medscape, 5/6/02
• Fibromyalgia: A Growth-Hormone Defect? - WebMD, 5/3/02 - "They found that growth-hormone levels went up in the healthy women, but not in the women with fibromyalgia ... What caused this growth-hormone defect? The researchers guessed that it might be too much of another hormone -- somatostatin -- which blocks growth hormone"
• Daytime Hypersomnolence Linked To Severity Of Fibromyalgia Symptoms - Doctor's Guide, 5/2/02
• Fibromyalgia Treatment Raises Eyebrows - WebMD, 4/19/02
• How do you treat fibromyalgia and does yoga or other forms of exercise work? - CNN, 4/4/02
• Fluoxetine Effective In Women With Fibromyalgia - Doctor's Guide, 3/28/02
• Fibromyalgia Husbands Suffer, Too - WebMD, 3/21/02
• Pain Scores Not an Accurate Reflection of Fibromyalgia Severity - Doctor's Guide, 11/16/01
• Bad News for Breast Implants, Leaky Silicone Implants Linked to Painful Condition - WebMD, 5/18/01 - "a recent study introduces a new twist: Women whose ruptured implants leak silicone into their bodies seem to have a higher incidence of a painful syndrome called fibromyalgia, a study shows"
• These Brain Waves May Tame Fibromyalgia, Electrotherapy Looks Promising -- but Are Results Too Good to Be True? - WebMD, 5/1/01
• Fibromyalgia: Brief, Intense Treatment Can Help - WebMD, 4/11/01 - "Three intense half-day sessions focusing on stress management, exercise, and relaxation therapies resulted in less pain, stiffness, anxiety, sleep disturbances, and other symptoms for a group of fibromyalgia sufferers"
• Brief Fibromyalgia Treatment Program Reduces Some Symptoms - Doctor's Guide, 4/10/01
• Low Doses Of Oral IFN-Alpha Offers Some Relief In Fibromyalgia - Doctor's Guide, 3/10/00
• Chronic Fatigue Associated With Additional Health Problems - Doctor's Guide, 1/10/01
• Low Doses Of Oral IFN-Alpha Offers Some Relief In Fibromyalgia - Doctor's Guide, 3/10/00
• Living with fibromyalgia - CNN, 8/3/99
• Anti-depression Drugs Effective in Treating Fibromyalgia - Doctor's Guide, 10/24/95
• Studies Cast Doubt on Link Between Silicone Implants and Rheumatic Disease - Doctor's Guide, 10/24/95