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Reminyl/Razadyne® (galantamine hydrobromide) (Janssen Pharmaceuticals, Titusville, New Jersey, 5/01)

Related Topics:

• Alzheimer's / Reminyl® (Galantamine hydrobromide) / Seroquel® (quetiapine) / Aricept™ (donepezil hydrochloride) / Exelon (rivastigmine tartrate) / Axura (memantine) / Procaine HCl

Where to purchase:

• Galantamine at International Anti-aging Systems

News & Research:

• Galantamine Effective, Well Tolerated in Patients with Alzheimer's Disease Unresponsive to Other Antidementia Medications - Doctor's Guide, 8/30/07
• Trio of Drugs May Improve Alzheimer's - WebMD, 1/25/06
• Cholinesterase inhibitors for patients with Alzheimer's disease: systematic review of randomised clinical trials - BMJ. 2005 Aug 6;331(7512):321-327 - "Because of flawed methods and small clinical benefits, the scientific basis for recommendations of cholinesterase inhibitors for the treatment of Alzheimer's disease is questionable"
• Razadyne ER (Galantamine Hydrobromide), Once-Daily Treatment, Now Available for Patients With Mild to Moderate Alzheimer's Disease - Doctor's Guide, 5/23/05
• Reminyl Renamed Razadyne to End Mix-Ups With Diabetes Rx - Clinical Psychiatry News, 5/05
• Alzheimer's Drug Linked to Higher Mortality - Clinical Psychiatry News, 3/05
• Long-Term Treatment With Reminyl (Galantamine) May Be Associated With Reduced Risk Of Institutionalisation In Patients With Dementia - Doctor's Guide, 11/9/04
• Galantamine Shows Safety and Efficacy As Tx for Dementia With Lewy Bodies - Clinical Psychiatry News, 10/04
• Dementia Drug Ineffective for Chronic Fatigue Syndome - HealthDay, 9/7/04
• Patients with Alzheimer's Disease who Discontinue Reminyl (Galantamine) Treatment with Seem to Experience Cognitive Decline - Doctor's Guide, 8/23/04
• Reminyl (Galantamine) May Help Patients With Alzheimer's Disease to Maintain Activities of Daily Living - Doctor's Guide, 8/23/04
• Switch Safe from Donepezil to Galantamine - Doctor's Guide, 5/19/04
• Galantamine Confers Benefits in Patients With Pure Vascular Dementia - Doctor's Guide, 4/29/04
• Reminyl (Galantamine) May Reduce Specific Behavioral Symptoms in Patients With Alzheimer's Disease - Doctor's Guide, 4/19/04
• Mild Alzheimer's Disease May Respond Well to Galantamine - Clinical Psychiatry News, 4/04
• Cognitive Benefits of Galantamine Sustained During Long-term Use - Medscape, 2/20/04
• Continuous Galantamine Therapy Slows Cognitive Decline In Alzheimer's Disease for Up to 3 Years - Doctor's Guide, 2/18/04
• Long-term Galantamine Shows Continued Safety, Efficacy in Patients with Vascular Dementia or Alzheimer's Disease with Cerebrovascular Disease - Doctor's Guide, 12/19/03
• ADHD Symptoms Respond To Cholinergic Drugs - Psychiatric News, 11/21/03
• Patients Treated With Alzheimer's Drug Reminyl (Galantamine HBr) Require Less Caregiver Time - Doctor's Guide, 10/28/03
• Drug Interactions with Cholinesterase Inhibitors: a Review - Doctor's Guide, 10/23/03
• Long-term Benefits of Galantamine Treatment for Patients with Vascular Dementia or Alzheimer's disease - Doctor's Guide, 9/23/03
• Long-Term Galantamine Therapy Safe, Effective for Dementia Patients - Doctor's Guide, 8/6/03
• Start Cholinesterase Inhibitor Immediately After Alzheimer's Dx - Clinical Psychiatry News, 6/03
• Long-Term Benefits Seen from Galantamine in Mild to Moderate Alzheimer's Disease - Doctor's Guide, 5/26/03
• Galantamine Achieves Sustained Cognitive Benefits for Alzheimer's Patients - Doctor's Guide, 5/17/03
• Antipsychotics Effective for Elderly Patients With Dementia - Psychiatric News, 4/18/03 - "atypical antipsychotics have been used to alleviate deteriorating behavioral symptoms in dementia patients, such as agitation and aggression. New research that she cited shows some atypical antipsychotics can actually improve cognition through activating the release of acetylcholine in the cortex. Clozapine, olanzapine, and risperidone, she reported, robustly increased acetylcholine release in the cortex, while ziprasidone only moderately increased levels, compared with haloperidol and thioridazine, which did not elevate acetylcholine levels at all ... atypical antipsychotics increase cortical dopamine and cholinesterase inhibitors at the very least increase cortical acetylcholine action, leading to an improvement in memory and thinking, as well as improvement in psychosis and behavior"
• Galantamine May Provide Long-term Non-cognitive Benefits in Alzheimer's Disease - Doctor's Guide, 3/6/03
• Galantamine Effective Long-term in Treating Vascular Dementia or Alzheimer's Disease - Doctor's Guide, 3/5/03
• Alzheimer’s Drugs May Offer Psychiatric Benefits - psychiatryonline.org, 2/7/02
• Drug Update: Alzheimer's Disease - Clinical Psychiatry News, 2/03
• Alzheimer's Drugs Help More Than Memory - WebMD, 1/7/03 - "Four such drugs have been approved by the FDA for use in the U.S. -- Reminyl, approved in 2001; Exelon, approved in 2000; Aricept, approved in 1996; and Cognex, approved in 1993, but rarely used now because it can cause liver problems ... treatment with one of these drugs for at least one month slowed the worsening of functional skills such as the ability to dress, bathe and shop. And it improved psychiatric symptoms including depression, hallucinations, delusions, anxiety, and apathy"
• Galantamine's Long-Term Safety, Efficacy In Alzheimer's Confirmed - Doctor's Guide, 10/15/02
• Effectiveness of Galantamine is Not Altered by Disease Severity - Doctor's Guide, 10/14/02
• Galantamine Delays Decline in Cognition by 12 to 18 Months - Doctor's Guide, 10/9/02
• Cognitive Decline Rapid and not Regained Following Discontinuation of Acetylecholinesterase Inhibitors - Doctor's Guide, 7/22/02
• Galantamine More Efffective and Less Costly Than Other Drugs in its Class - Doctor's Guide, 7/22/02
• Galantamine Hydrobromide Delays Alzheimer's Symptoms by 18 Months - Doctor's Guide, 5/23/02
• Study Suggests Reminyl May Provide Long-Term Benefits in Treating Alzheimer's Disease - Doctor's Guide, 5/22/02
• Galantamine Improves Broad Spectrum of Symptoms in Elderly Patients with Alzheimer's Disease - Doctor's Guide, 5/15/02
• Acetylcholinesterase Inhibitors Improve Behavior - Clinical Psychiatry News, 4/02
• Galantamine Shows Lasting Benefits in Alzheimer's Disease Patients - Doctor's Guide, 4/18/02
• Aricept Wins First Head-to-Head Match-Up Against Reminyl - WebMD, 4/12/02
• Galantamine Showing Early Promise In Some Dementias - Doctor's Guide, 4/11/02
• Aricept (Donepezil) Significantly Improves Cognition/Daily Living over Reminyl (Galantamine) in Alzheimer's Disease - Doctor's Guide, 4/4/02
• Reminyl (Galantamine) May Ease Both Patient/Caregiver Burden in Alzheimer’s - Doctor's Guide, 9/14/01
• New Alzheimer’s Drug, Reminyl (Galantamine), Effective in Mixed/Vascular Dementia - Doctor's Guide, 6/19/01
• Alzheimer's Drug: Benefits Seen for Two Years, Advantages of Reminyl Are Modest, Though - WebMD, 5/16/01 - "At the end of two years, those who took the drug throughout the study had on average slightly less than half the degree of decline in mental function and physical abilities of those who initially received the placebo pill"
• Drug Therapy [Reminyl (galantamine hydrobromide)] Can Treat Dementia In Patients With Cerebrovascular Disease - Doctor's Guide, 5/10/01
• FDA Approves Reminyl (Galantamine Hydrobromide) For Mild To Moderate Alzheimer’s Disease - Doctor's Guide, 3/1/01
• Reminyl (Galantamine) Offers Hope In Alzheimer's Disease - Doctor's Guide, 6/26/00
• Galantamine improves symptoms of Alzheimer's - Doctor's Guide, 5/5/00
• Investigational Alzheimer’s Drug, Reminyl (Galantamine), Improves Memory And Behavior - Doctor's Guide, 4/7/00
• Galantamine Improves Memory And Learning Ability In Alzheimer’s Patients - Doctor's Guide, 7/20/98

Abstracts:

• Cholinesterase inhibitors for patients with Alzheimer's disease: systematic review of randomised clinical trials - BMJ. 2005 Aug 6;331(7512):321-327 - "Because of flawed methods and small clinical benefits, the scientific basis for recommendations of cholinesterase inhibitors for the treatment of Alzheimer's disease is questionable"