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Home >
Health Conditions > Schizophrenia >
Antidepressants & Psychotropics > Risperdal®
(risperidone)
Risperdal® (risperidone)
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News & Research:
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Risperdal (risperidone) - rxlist.com
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Risperidone at drugstore.com
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Newer Antipsychotic Drugs Increase the Risk of Sudden Cardiac Death -
WebMD, 1/14/09 - "because these older agents cause
movement disorders in some patients, they have largely been replaced with
newer medications such as Zyprexa, Risperdal, and Seroquel ... Although the
study's results reaffirmed that people who use the older antipsychotic drugs
are twice as likely as nonusers to have sudden cardiac death, it also showed
a similar increase in risk for the newer medications. For these, the rate of
sudden cardiac death was more than twice that for nonusers"
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Antipsychotic Drug May Treat Depression - WebMD, 11/2/07 -
"depression was in remission for about 24.5% of the
Risperdal patients, compared with almost 11% of those taking the placebo"
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FDA Approves Extended-Release Drug for Schizophrenia - Clinical
Psychiatry News, 1/07
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Adjunctive Risperidone Effective for Treatment-Resistant Major Depressive
Disorder - Doctor's Guide, 9/22/06
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Study Finds Long-Acting Risperidone Associated With Low Relapse Rates -
Doctor's Guide, 9/8/06
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Study Confirms Seroquel(R) as Effective as Risperidone for Treatment of
Schizophrenia - Doctor's Guide, 8/3/06
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Orally Disintegrating Risperidone Tablets in Patients With Major Depressive
Disorder, Bipolar Disorder or Dementia - Doctor's Guide, 5/24/06
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New Dosages of Risperdal (Risperidone) Now Available - Doctor's Guide,
3/24/06
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Study Shows Equivalent Efficacy and Superior Tolerability of Quetiapine
Compared to Risperidone in the Treatment of Schizophrenia - Doctor's
Guide, 1/4/06
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Risperidone Use Linked to Pituitary Tumors - Clinical Psychiatry News,
1/06
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Risperidone Eases Some Symptoms of Dementia: Dose of about 1 mg per day
brings improvements, but risk of cerebrovascular events rises threefold
- Clinical Psychiatry News, 11/05
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Interim Results Show Long-Acting Injectable Risperidone Comparable in
Efficacy and Safety as Oral Antipsychotic in Bipolar Disorder - Doctor's
Guide, 11/14/05
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Older Adults with Treatment-Resistant Depression Respond to Risperidone
- Doctor's Guide, 10/31/05
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CAFE Study Shows
Varying Benefits Among Atypical Antipsychotics - Medscape, 10/25/05
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Atypical Antipsychotics Offer Equivalent Benefit in First-Episode Psychosis
- Doctor's Guide, 10/25/05
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Risperidone Provides Some Improvement in Behaviour for Children with Autism
- Doctor's Guide, 10/24/05
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Antipsychotic Drugs: OK for Dementia Patients? - WebMD, 10/18/05
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Olanzapine vs. Risperidone in Schizophrenia - Clinical Psychiatry News,
9/05
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New Study Suggests Patients With Schizophrenia Improved With Treatment
Change to Risperdal Consta (Risperidone) - Doctor's Guide, 8/4/05
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Antipsychotic Drug May Help Kids With Autism - WebMD, 7/1/05
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Second-Generation Antipsychotics Equally Effective in Schizophrenia -
Medscape, 6/30/05
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Many Patients With Schizophrenia Who Transitioned to Risperdal Consta
Avoided Relapse and Experienced Symptom Improvement - Doctor's Guide,
6/16/05
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Geodon as Effective as, and Better Tolerated Than, Risperdal for
Schizophrenia Treatment, First Head-to-Head Study Shows - Doctor's
Guide, 1/21/05
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Long-Term Treatment With Zyprexa (Olanzapine) Appears to Reduce Violent
Behavior in People With Schizophrenia Compared To Risperidone - Doctor's
Guide, 12/14/04
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Risperidone Linked to Several Improvements in Children With Autism -
Doctor's Guide, 10/22/04
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Some Anti-Psychotic Medications May Trigger Diabetes - Science Daily,
10/8/04 -
"The rate is five to 10 times higher than the
estimated rate of 6.3 cases per 1,000 in the general U.S. population"
- Risperidone
Associated With Increased Risk of Hyperglycemia, Diabetes - Medscape,
8/5/04
- Seizure
Drug Combats Antipsychotic Side Effects - Psychiatric News, 6/18/04
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Concern About Increased Stroke Risk With Risperidone Unfounded -
Doctor's Guide, 6/21/04
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Risperdal (Risperidone) Shown to Rapidly Reduce Manic Symptoms Associated
With Bipolar I Disorder - Doctor's Guide, 6/2/04
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Risperidone Helps Reduce Psychosis in Alzheimer's Patients - Doctor's
Guide, 5/20/04
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Risperidone Appears Safe, Effective in Children With Severe Disruptive
Behaviours and Below-Average Intelligence - Doctor's Guide, 5/5/04
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Risperidone Might Be Effective as Augmentation in Treatment-Resistant
Patients With Generalized Anxiety Disorder - Doctor's Guide, 3/22/04
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Glycine Reduces Negative And Cognitive Symptoms in Schizophrenic Patients
Taking Olanzapine Or Risperidone - Doctor's Guide, 3/16/04 - See
Vitacost
glycine products.
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Risperidone Might Be Safe and Effective Augmentative Treatment for Anxiety
Disorders - Doctor's Guide, 3/15/04
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Risperdal Consta (Risperidone Long-Acting Injection) Significantly Reduces
Need for Institutional Psychiatric Care - Doctor's Guide, 2/10/04
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Study Demonstrates Key Benefits of Risperdal Consta (Risperidone Long Acting
Injection) In Young Adults With Schizophrenia - Doctor's Guide, 2/10/04
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Haloperidol and Risperidone May Produce Opposite Effects on Human
Corticospinal System in Schizophrenic Patients - Doctor's Guide, 1/15/04
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FDA Approves Risperdal (Risperidone) for Treatment of Bipolar Mania -
Doctor's Guide, 12/5/03
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Risperdal Consta (Risperidone), Newer-Generation Schizophrenia Treatment,
Now Available in US - Doctor's Guide, 12/4/03
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Risperidone Appears Safe, Effective as Augmentation Strategy in Patients
With Resistant Obsessive-Compulsive Disorder - Doctor's Guide, 12/2/03
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FDA Approves Risperdal (Risperidone) Consta for Treating Schizophrenia -
Doctor's Guide, 10/30/03
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Risperidone-associated Steatohepatitis and Excessive Weight-gain -
Pharmacopsychiatry. 2003 Sep;36(5):206-7
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Risperidone Reduces Disruptive Behavior and Severe Mood Disregulation in
Children - Doctor's Guide, 10/17/03
- FDA to
Require Diabetes Warning On Antipsychotics - Psychiatric News, 10/17/03
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Weight Gain is Potential Problem in Patients Switched from Risperidone to
Olanzapine - Doctor's Guide, 10/16/03
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Risperidone Reduces Aggression in Children With Disruptive Behaviour
Disorders - Doctor's Guide, 10/14/03
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Switch From Oral Olanzapine to Depot Risperidone Safe, May Improve Symptoms
- Doctor's Guide, 10/3/03
- Risperidone May
Lower Risk of Falls - Psychiatric Times, 10/03
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Therapeutic Dose Equivalency Calculation Method Proposed for Atypical
Antipsychotic Medications - Doctor's Guide, 7/16/03 -
"The reported minimum effective doses identified
were 4 mg/day for risperidone, 10 mg/day for olanzapine, 150 mg/day for
quetiapine, 120 mg/day for ziprasidone, 15 mg/day for aripiprazole, and 4
mg/day for haloperidol"
- Long-Acting
Risperidone Well Tolerated, Effective in Schizophrenia - Medscape,
6/6/03
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Risperdal Consta (Risperidone) Provides Significant Schizophrenia Symptom
Relief - Doctor's Guide, 6/2/03
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Motor and Sexual Side Effects More Likely with Risperidone than Quetiapine
- Doctor's Guide, 5/23/03
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Risperdal (Risperidone) Quick Dissolve Tablets Launched In US - Doctor's
Guide, 5/6/03
- Risperidone Linked to
Stroke, Transient Ischemic Attack - Medscape, 4/25/03
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Antipsychotics Effective for Elderly Patients With Dementia -
Psychiatric News, 4/18/03 -
"atypical
antipsychotics have been used to alleviate deteriorating behavioral
symptoms in dementia patients, such as agitation and aggression. New
research that she cited shows some atypical antipsychotics can actually
improve cognition through activating the release of acetylcholine in the
cortex. Clozapine,
olanzapine, and risperidone, she reported, robustly increased
acetylcholine release in the cortex, while
ziprasidone only moderately increased levels, compared with
haloperidol and thioridazine, which did not elevate acetylcholine levels
at all ... atypical antipsychotics increase cortical dopamine and
cholinesterase inhibitors at the very least increase cortical
acetylcholine action, leading to an improvement in memory and thinking, as
well as improvement in psychosis and behavior"
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Risperidone Shows Efficacy in Post Traumatic Stress Disorder - Doctor's
Guide, 4/1/03
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Risperidone Demonstrates Conventional Antidepressant Characteristic -
Doctor's Guide, 3/19/03
- Antipsychotics and
Glucose Dysregulation: Their Relationship to Treatment Decisions -
Psychiatric Times, 3/03
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Multi-Trial Analysis Shows Risperidone Effective in Treating
Dementia-Related Agitation, Aggression - Doctor's Guide, 3/6/03
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Non-aggressive Symptoms in Dementia Patients Also Respond to Risperidone
- Doctor's Guide, 3/5/03
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Risperidone More Effective than Conventional Neuroleptics in Reducing
Dementia Symptoms - Doctor's Guide, 3/4/03
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Risperidone Safe for Tx of Disruptive Behavior Disorders - Clinical
Psychiatry News, 3/03
- Amisulpride as Good
as Risperidone in Chronic Schizophrenia - Medscape, 1/8/03
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Hippocampal Volume May Predict Response of Schizophrenics to Risperidone
- Doctor's Guide, 11/29/02
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Risperdal (Risperidone) Relieves Affective Symptoms in Children with
Disruptive Behaviour Disorders - Doctor's Guide, 10/29/02
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Risperidone (Risperdal) Beneficial in Children Pervasive Developmental
Disorder - Doctor's Guide, 10/28/02
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Risperidone Effective In Children With Low Intelligence/Disruptive
Behaviours - Doctor's Guide, 10/22/02
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Updated Safety Information For Risperdal* (Risperidone) In Elderly Dementia
Patients, Announced In Canada - Doctor's Guide, 10/18/02
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Risperidone Effective in Treating Disruptive Behaviours In Children With
Subaverage IQ - Doctor's Guide, 9/10/02
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Olanzapine Versus Risperidone: A Comparison Of Hospital Length Of Stay In
Adult Inpatients With Schizophrenia - Doctor's Guide, 9/2/02
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Risperidone Effective For Nursing Home Population With Behavioural And
Psychological Symptoms Of Dementia - Doctor's Guide, 8/29/02
- Risperidone Controls
Behavior in Children With Subaverage IQ - Medscape, 8/14/02
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Risperdal Consta to be Launched in United Kingdom - Doctor's Guide,
8/12/02
- Germany Approves Risperdal
Consta (Risperidone), First Atypical Antipsychotic To Be Available As
Long-Acting Injection - Doctor's Guide, 8/1/02
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Risperidone For Autistic Children Appears To Control Aggressive Behaviour
- Doctor's Guide, 8/1/02
- Schizophrenia Drug
[Risperdal] Helps Autistic Kids - WebMD, 7/31/02
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Research Suggests Risperdal (Risperidone) Improves Treatment of manic phase
of Bipolar Disorder - Doctor's Guide, 7/24/02
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Rivastigmine-Risperidone Co-administration Safe in Dementia Patients with
Behavioural Disturbances - Doctor's Guide, 7/23/02
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Pooled Analysis Supports Risperidone As First-Line Treatment For Behavioural
and Psychological Symptoms of Dementia - Doctor's Guide, 7/23/02
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Low-Dose Risperidone Demonstrates Efficacy in Nonaggressive Agitated
Patients with Dementia - Doctor's Guide, 7/22/02
- Risperidone Plus Mood
Stabilizer Helpful in Acute Mania - Medscape, 7/18/02
- Risperidone Improves
Disruptive Behavior in Intellectually Handicapped Children - Doctor's
Guide, 6/28/02
- Long-Acting Risperidone
Injections Decrease Hospitalization Rates for Schizophrenia Patients -
Doctor's Guide, 6/28/02
- Switching to Risperidone
Has Positive Impact on Caregivers, Patients with Dementia - Doctor's
Guide, 6/26/02
- Ziprasidone Has Fewer Side
Effects than Risperidone in Patients with Schizophrenia - Doctor's
Guide, 6/26/02
- Risperidone/Topiramate
Combination Effective for Bipolar Disorder - Doctor's Guide, 6/26/02
- Outpatient Risperidone
Effective for Dementia Symptoms - Doctor's Guide, 6/25/02
- Optimal
Management of Psychosis & Agitation in the Elderly - Medscape, 3/20/02
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Risperdal (Risperidone) Approved For Delaying Relapse In Long-Term Treatment
Of Schizophrenia - Doctor's Guide, 3/14/02
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Risperidone and Olanzapine May Reduce Risk of Extrapyramidal Symptoms -
Doctor's Guide, 1/17/02
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Anti-Metabolic Effects Of Risperidone May Counter Psychosis - Doctor's
Guide, 1/16/02
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Risperidone Reduces Relapse Risk In Schizophrenics - Doctor's Guide,
1/3/02
- Injectable Antipsychotic
Risperdal Consta (Risperidone) Significantly Improves Schizophrenia Symptoms
- Doctor's Guide, 12/17/01
- Anti-Psychotic Seroquel
(Quetiapine) Equal In Efficacy And Tolerability To Risperidone, Better
Symptom Profile - Doctor's Guide, 12/6/01
- Oral Risperidone Safe and
Effective for Long-Term Treatment of Behaviour Disorders - Doctor's
Guide, 11/19/01
- Newer Antipsychotics
Linked to Weight Gain - Doctor's Guide, 11/19/01
- Risperidone Safe And
Effective For Dementia-Related Behavioral And Psychological Problems -
Doctor's Guide, 6/18/01
- Quetiapine (Seroquel) Has
Important Advantages Over Commonly Prescribed Agents In Treating
Schizophrenia - Doctor's Guide, 5/8/01 -
"while equally effective in alleviating the symptoms
of schizophrenia, has important tolerability advantages over other commonly
prescribed agents ... quetiapine was not associated with significant weight
gain ... sexual dysfunction is a frequent side effect of risperidone,
olanzapine, and haloperidol, but not of quetiapine ... results revealed that
the quetiapine patient group experienced a much lower incidence of EPS than
the other agents in the study"
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Risperidone, Clozapine Seem Equally Effective In Refractory Schizophrenia
- Doctor's Guide, 10/25/00
- Risperidone May Treat
Aggression In Youths - Doctor's Guide, 10/27/99
- Risperidone More Cost
Effective Than Olanzapine - Doctor's Guide, 9/24/99
- Risperidone Reduces
Aggression and Agitation in Patients with Severe Dementia - Doctor's
Guide, 9/22/99
- Zyprexa Reduces
Hyperprolactinemia Prevalence In Schizophrenia Patients - Doctor's
Guide, 8/2/99
- Study Compares Two Main
Schizophrenia Drugs - Doctor's Guide, 5/21/97
Abstracts:
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Risperidone for
treatment-refractory major depressive disorder: a randomized trial - Ann
Intern Med. 2007 Nov 6;147(9):593-602 - "Risperidone
augmentation produced a statistically significant mean reduction in
depression symptoms, substantially increased remission and response, and
improved other patient- and clinician-rated measures"
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Placebo-Controlled Study of Relapse Prevention With Risperidone Augmentation
in Older Patients with Resistant Depression - Am J Geriatr Psychiatry.
2007 Oct 10 - "In older patients with resistant
depression and poor response to standard treatments, risperidone
augmentation resulted in symptom resolution in a substantial number of
patients and a nonsignificant delay in time to relapse"
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Glucose and lipid metabolism of long-term risperidone monotherapy in
patients with schizophrenia - Psychiatry Clin Neurosci. 2007
Feb;61(1):54-8 - "The body fat percentage (P =
0.0018), body mass index (BMI) (P = 0.0150), fasting blood glucose (P =
0.0358), triglyceride (P = 0.0377), leptin (P = 0.0243), total ghrelin (P =
0.0067), active ghrelin (P = 0.0241) and prolactin (P < 0.0001) levels of
patients treated with risperidone were significantly higher than those of
healthy volunteers, while the HDL-cholesterol level (P = 0.0222) was
significantly lower"
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Risk of diabetes mellitus associated with atypical antipsychotic use among
medicaid patients with bipolar disorder: a nested case-control study -
Pharmacotherapy. 2007 Jan;27(1):27-35 -
"the risk of diabetes was greatest among patients
taking risperidone (hazard ratio [HR] 3.8, 95% confidence interval [CI]
2.7-5.3), olanzapine (3.7, 95% CI 2.5-5.3), and quetiapine (2.5, 95% CI
1.4-4.3). The risk for developing diabetes was also associated with weight
gain (HR 2.5, 95% CI 1.9-3.4), hypertension (HR 1.6, 95% CI 1.2-2.2), and
substance abuse (HR 1.5"
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An Assessment of the Independent Effects of Olanzapine and Risperidone
Exposure on the Risk of Hyperlipidemia in Schizophrenic Patients -
Archives of General Psychiatry, 11/02 -
"Olanzapine use was associated with nearly a 5-fold
increase in the odds of developing hyperlipidemia compared with no
antipsychotic exposure"
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