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Recent Longevity News for the week ending 9/13/17

The Longevity Pill - Today.com, 9/8/17 - See the video.  I've been saying that about metformin since Moby-Dick was a minnow.  See metformin at The Antiaging Store.

Substance in coffee delays onset of diabetes in laboratory mice - Science Daily, 9/6/17 - "Two of the groups were fed differing doses of cafestol. After 10 weeks, both sets of cafestol-fed mice had lower blood glucose levels and improved insulin secretory capacity compared to a control group, which was not given the compound. Cafestol also didn't result in hypoglycemia, or low blood sugar, a possible side effect of some antidiabetic medications. The researchers conclude that daily consumption of cafestol can delay the onset of Type 2 diabetes in these mice, and that it is a good candidate for drug development to treat or prevent the disease in humans"

Improved vaccine that protects against nine types of HPV is highly effective - Science Daily, 9/6/17 - "HPV is an extremely common virus. It is estimated that by age 50, four out of five women have been infected with the virus at one point throughout their lifetimes. HPV causes ailments such as genital and anal warts and, in some instances, continued infection can lead to the development of benign or cancerous growths of the cervix, vulva, vagina, anus, penis, tonsils, and base of the tongue. There are more than 100 types of HPV, but only approximately 13 types are associated with cancer development. HPV 16 and 18 alone are estimated to cause 70 percent of all cervical cancers ... 9vHPV, known as Gardasil 9, became available in 2015 to protect females and males ages 9 through 26 years against HPV-associated cancers and genital warts"

Cannot sleep due to stress? Here is the cure - Science Daily, 9/5/17 - "Octacosanol reduced corticosterone level in blood plasma, which is a stress marker. The octacosanol-administered mice also showed normal sleep, which was previously disturbed due to stress. They therefore claim that the octacosanol mitigates stress in mice and restores stress-affected sleep to normal in mice. The sleep induced by octacosanol was similar to natural sleep and physiological in nature. However, authors also claimed that octacosanol does not affect sleep in normal animals. These results clearly demonstrated that octacosanol is an active compound that has potential to reduce stress and to increase sleep, and it could potentially be useful for the therapy of insomnia caused by stress" - See policosanol at Amazon.com.

Abstracts from this week:

Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway - Biochem Biophys Res Commun. 2017 Sep 4 - "Altogether, these data suggested that curcumin inhibited the activities of BCSCs through suppressing Shh pathway, which might be an effective chemopreventive agent for bladder cancer intervention" - See curcumin products at Amazon.com.

The Association Between the Use of Zolpidem and the Risk of Alzheimer's Disease Among Older People - J Am Geriatr Soc. 2017 Sep 7 - "Zolpidem [Ambien] users with a high cumulative dose (>180 cDDD) in the first year after initiation had a significantly greater risk of Alzheimer's disease than non-zolpidem users (HR = 2.97, 95% CI = 1.61-5.49) and low cumulative dose (<28 cDDD) users (HR = 4.18"

Neat Tech Stuff / "How To's":

6 Aromatherapy Essential Oils for Stress Relief and Sleep - Huffington, 4/29/16 - "Lavender essential oil is one of the most well-studied essential oils in terms of its relaxing effects. One study found that lavender oil aromatherapy calmed the nervous system — lowering blood pressure, heart rate, and skin temperature as well as changing brain waves to a more relaxed state.

Lavender can also help with mild insomnia and provide better quality of sleep. Lavender aromatherapy has also been found to help reduce anxiety and depression in women with postpartum depression. Lavender has also been found to help reduce anxiety in many medical settings, such as dental offices, the intensive care unit, and during preparations before surgery.

The scent of lavender stimulates brain pathways, including our limbic system, which is connected to our emotional response and memories. Studies using electroencephalography (EEG), which measures brain waves, and brain imaging using functional magnetic resonance imaging (fMRI) show significant changes during lavender aromatherapy consistent with its relaxing effects"


Health Focus (Iron):