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Stomach Ulcers/H. Pylori

Popular Supplements:

• Deglycyrrhizinated Licorice (DGL) / aloe / probiotics

Alternative News:

• Probiotic identified to treat ulcers - Science Daily, 2/24/11 - "H. pylori is considered one of the major risk factors underlying the development of gastritis and gastric and duodenal ulcers ... Currently, antibiotic-based treatment for H. pylori infection is neither sufficient nor satisfactory, with the most successful treatments reaching 75 to 90% eradication rates ... Among probiotics Bifidobacterium is one of the favorite genera in studies focused on the prevention of gastrointestinal infection and is often used in fermented dairy products or food supplements ... They identified one strain (Bifidobacterium bifidum CECT 7366) that under certain conditions had an inhibition level of nearly 95% in vitro and tested its activitity against infection in mi ... After 21 days, mice treated with the potentially probiotic strain developed significantly less ulcers than the control group" - See probiotics at Amazon.com.
• Effect of resveratrol on helicobacter pylori-induced interleukin-8 secretion, reactive oxygen species generation and morphological changes in human gastric epithelial cells - Biol Pharm Bull. 2009 Nov;32(11):1931-5 - "preincubation of the cells with 75 and 100 muM of resveratrol significantly (p<0.05 and p<0.01 respectively) inhibited the secretion of IL-8 from H. pylori-infected cells. In addition, resveratrol pretreatment at 1-100 muM suppressed H. pylori-induced ROS generation in a concentration dependent manner. Moreover, H. pylori-initiated morphological changes were markedly blocked by resveratrol. Hence, resveratrol can be considered as a potential candidate against various H. pylori related gastric pathogenic processes" - See resveratrol products at Amazon.com.
• Glutamine Supplements Show Promise In Treating Stomach Ulcers - Science Daily, 5/15/09 - "the amino acid glutamine, found in many foods as well as in dietary supplements, may prove beneficial in offsetting gastric damage caused by H. pylori infection ... at six-weeks-post infection, the animals exhibited increased expression of three cytokines – interleukin 4, interleukin 10 and transforming growth factor-alpha mRNA. "These all play an important role in the stomach's ability to protect against damaging effects resulting from other responses to H. pylori infection ... Of even greater significance, by week 20, the study results showed that, among the H. pylori-infected animals, the mice that were fed the L-glutamine diet exhibited lower levels of inflammation than did the mice that received the standard control diet" - See L-glutamine at Amazon.com.
• New Yogurt Fights Stomach Ulcers - WebMD, 3/22/09 - "H. pylori uses an enzyme called urease to attach to and infect the inside of the stomach. This latest yogurt, designed to fight stomach ulcers, contains an antibody called IgY-urease. The yogurt is marketed as Dr. Piro in Japan and as Gut in Korea. Researchers are hopeful that their clinical trial will pave the way for approval in the United States ... For the trial, scientists recruited 42 people who tested positive for H. pylori. Some participants ate the yogurt with the antibody three times a day for four weeks. Some participants ate the same amount of regular yogurt that didn't contain the antibody. H. pylori activity was significantly reduced in the antibody yogurt group"
• Grape Extracts May Be Effective Against Harmful Gut Bacteria - Science Daily, 3/4/09 - "H. pylori is the bacterial agent most commonly associated with peptic ulcers, gastritis, mucosa-associated lymphoid tissue lymphoma, and gastric cancer ... The antibacterial effects of extracts from red, white, black and muscadine grapes as well as the pure compounds resveratrol, ellagic acid, and myricetin were tested for anti-H. pylori activity using agar dilution, laser scanning microscopy and cell proliferation. Following 24 hour treatment, results showed that muscadine grape skin extract had the highest anti-H. pylori effect, followed by muscadine grape synergy and seed extract. Additionally, two of the three compounds, resveratrol and ellagic acid, also inhibited H. pylori" - See grape seed extract at Amazon.com and resveratrol products at Amazon.com.
• Cyanocobalamin May be Beneficial in the Treatment of Recurrent Aphthous Ulcers Even When Vitamin B12 Levels Are Normal - Am J Med Sci. 2008 Nov;336(5):379-382. - "recurrent aphthous ulcers (RAUs) ... vitamin B12 (cobalamin) ... cobalamin normal group (CNG) ... A significant increase in cobalamin levels was observed after cyanocobalamin treatment in both groups. A significant decrease in aphthous ulcer frequency was also concurrently observed. 96% of the patients showed good response to replacement treatment, 4% of the study population did not respond to the treatment ... Cyanocobalamin treatment maybe beneficial for patients with RAU even when serum cobalamin levels are normal. We suggest that higher serum cobalamin levels should be attained in patients with RAU for mucosal protection" - See vitamin B12 at Amazon.com.
• Olive Oil May Prevent Ulcers - WebMD, 2/13/07 - "A new Spanish study suggests virgin olive oil may help prevent and treat H. pylori infections, which are responsible for millions of cases of gastritis and ulcers each year"
• Probiotic Yogurt May Help Eradicate H. pylori Infection - Medscape, 4/17/06
• Broccoli fights cancer-causing bacteria in humans - Nutra USA, 11/3/05
• Grapefruit Seed Extract May Help Ulcers Heal - WebMD, 5/17/05
• Battling Ulcers? - Dr. Weil, 4/1/05
• Regular Intake of Yogurt Can Suppress H. pylori Infection - Medscape, 9/2/04
• Effects of ingesting Lactobacillus- and Bifidobacterium-containing yogurt in subjects with colonized Helicobacter pylori - Am J Clin Nutr. 2004 Sep;80(3):737-41 - "Regular intake of yogurt containing Bb12 and La5 effectively suppressed H. pylori infection in humans"
• Ulcer Agent Lowered in Vitamin C Study - Natural Foods Merchandiser, 11/03
• Can Vitamin C Prevent Ulcers? - Dr. Weil, 8/28/03
• Vitamin C May Protect Against Ulcer-Causing Bacteria - Doctor's Guide, 8/1/03 - "the lower the level of vitamin C in the blood the more likely a person will become infected by Helicobacter pylori, the bacteria that can cause peptic ulcers and stomach cancer ... The bottom line is that higher levels of vitamin C may have the potential to prevent peptic ulcers and stomach cancer"
• Low Levels of Serum Vitamin B May Be Related to Helicobacter Pylori Infection - Doctor's Guide, 2/14/03 - "Of 25 subjects with vitamin B >145-180 pg/mL, 92% were seropositive ... Eighty-nine percent of the 47 subjects with vitamin B greater than 180-250 pg/mL were found to be seropositive compared with 51%, 31 out of 61, of subjects with B less than 250 pg/mL" - [abstract] - See the abstract.  I think they are talking about vitamin B12.  See vitamin B12 at Amazon.com.
• With Beer or Wine, The Stomach's Fine - WebMD, 12/30/02
• Vitamins C And E Do Not Aid In Helicobacter Pylori Eradication - Doctor's Guide, 11/7/02
• “Friendly Bacteria” Help Eradicate the Peptic-Ulcer Organism - New Hope Natural Media, 10/17/02 - "Taking a supplement of “friendly bacteria” (probiotics) increases the effectiveness of conventional antibiotic therapy in eradicating Helicobacter pylori (H. pylori), the organism that causes peptic ulcers"
• Egg Yolk A Possible Alternative To Antibiotic Treatment Of Ulcers - Intelihealth, 9/20/02
• Broccoli Beats Ulcers, Cancer - WebMD, 5/28/02
• Lactobacillus GG A Premier Probiotic - Nutrition Science News, 6/01 - "In a third study, 60 subjects with asymptomatic Helicobacter pylori infection (the bacterial ulcer perpetrator) used LGG (12 billion live bacteria/day) during H. pylori eradication therapy. Subjects using LGG experienced significantly fewer side effects, all of which were less severe compared with placebo"
• Vitamin B12: Surprising New Findings - Life Extension Magazine, 12/00 - "Researchers have discovered a connection between anemia, B12 deficiency, and infection with H. Pylori, the organism that causes stomach ulcers."
• Probiotics Counter Antibiotics - Nutrition Science News, 12/00

News & Research:

• Ulcer bacteria may contribute to development of Parkinson's disease - Science Daily, 5/22/11 - "Infection of late middle-aged mice with a particular strain of the bacteria Helicobacter pylori results in development of Parkinson's disease symptoms after 3-5 months ... Our mouse model demonstrates a direct effect of H. pylori infection on the development of Parkinson's disease. The observation that not all H. pylori strains are equally able to cause symptoms will allow us to investigate bacterial factors and/or immune response to H. pylori infection that increase the risk for Parkinson's disease"
• Helicobacter pylori infection linked to decreased iron levels in otherwise healthy children - Science Daily, 3/7/11 - "Half of the world's population is infected with H. pylori and most of the individuals are asymptomatically infected ... Previous research has shown that iron levels correlate with several body functions including brain activity and have well documented long-term health consequences such as increased morbidity and mortality and loss of productivity ... the infection causes a decrease in the levels of iron in children who do not have anemia or an iron deficiency. The bacterium H. pylori infects the lining of the stomach resulting in chronic swelling of tissue, a condition known as gastritis. H. pylori is also a major cause of peptic ulcer disease and the cause of most cancers of the stomach ... Over time markers of iron stored in the body increased in children no longer infected. However, children who remained infected lagged in levels of one marker, serum ferritin, at their six month follow-up. The protein serum ferritin measures the amount of iron stored in your body"
• Cancer-causing bacterium targets tumor-suppressor protein - Science Daily. 8/2/10
• ACE Inhibitors May Protect Diabetics From Cancer, Peptic Ulcer - Medscape, 12/19/08 - "There was a significant association between ACE inhibitor use and the risk for cancer, with an adjusted odds ratio of 0.59 ... The rate of cancer among users of ACE inhibitors was 10% vs 15% for nonusers ... There was also a significant association between ACE inhibitor use and peptic ulcer disease, with an odds ratio of 0.68 ... The rate of peptic ulcer disease among ACE inhibitor users was 12% vs 16% among nonusers"
• Stomach Ulcer Bug Causes Bad Breath - Science Daily, 11/24/08
• High-salt diet link to ulcer risk - BBC News, 5/22/07
• Treatment Reduces Gastric Ulcers in at-Risk Patients Using Long-Term NSAIDS - Doctor's Guide, 3/30/06
• Nexium Can Reduce Stomach Ulcer in High Risk Patients - Doctor's Guide, 3/23/06
• Nexium Shown to Reduce Gastric Ulcers in At-Risk Patients Using Long-Term NSAIDs - Doctor's Guide, 3/22/06
• New Treatment for Bleeding Ulcers Reduces Surgery, Death Rates - Doctor's Guide, 1/25/06
• Everyday Pain Relief: Ulcers - WebMD, 5/26/05
• FDA Approves New Indication for Nexium (Esomeprazole Magnesium), Now Also for Reduced Risk of Stomach Ulcer Development Among NSAID Users - Doctor's Guide, 11/29/04
• Pantoprazole Tops Ranitidine for Prevention of Rebleeding in High-Risk Ulcer Patients - Doctor's Guide, 5/21/04
• Eradication of Helicobacter pylori: A Clinical Update - Medscape, 2/17/04
• Helicobacter pylori Eradication Therapy May be Highly Effective Treatment for Gastric Marginal Zone B cell Lymphoma of Mucosa Associated Lymphoid Tissue - Doctor's Guide, 1/15/04
• Levofloxacin May Be Effective Option in Second Line Treatment of Helicobacter pylori Infection - Doctor's Guide, 12/5/03
• Chronic Urticaria Remission More Likely After Helicobacter Pylori Eradication - Doctor's Guide, 11/28/03
• Somatostatin Maintains High Intragastric pH in Patients With Peptic Ulcer Bleeding - Doctor's Guide, 11/6/03
• Endoscope-Delivered Laser Kills Helicobacter Pylori - Doctor's Guide, 10/20/03
• Quinolone-Based Triple Therapy May Be Superior to Conventional Treatment for H. Pylori Eradication - Doctor's Guide, 10/15/03
• One-Day Quadruple Therapy Effective for H. pylori Infection - Medscape, 9/23/03
• Stool Test Predicts H. pylori Infection in Children - Medscape, 6/27/03
• Presumptive Diagnosis of Peptic Ulcer Disease Often Incorrect - Medscape, 5/30/03
• H. pylori Eradication Can Result in Significant Weight Gain - Medscape, 5/27/03
• New Triple-Therapy Regimen Eradicates Helicobacter Pylori - Doctor's Guide, 5/25/03
• Race Not a Factor in H.Ppylori Treatment - Doctor's Guide, 5/25/03
• Helicobacter pylori May Help Lower Risk for Oesophageal Cancer - Doctor's Guide, 5/23/03
• Test-And-Treat Strategy Preferred Approach In Treating Dyspepsia - Doctor's Guide, 5/22/03
• NSAIDs Cause Ulcers and Bleeding in Small Intestine - Doctor's Guide, 5/21/03 - "Research using video capsule endoscopy (VCE) shows small intestinal ulcerations, lesions, and bleeding related to the use of nonsteroidal anti-inflammatory drugs (NSAIDs) occur 40% more often than previously thought"
• Pantoprazole Treatment Prevents Relapse over Three Years in Erosive Esophagitis - Doctor's Guide, 5/19/03
• Somatostatin Secretion into the Gastric Juice Enhanced, Basal Acid Output Recovered Following Helicobacter Pylori Eradication in Gastric Ulcers - Doctor's Guide, 5/6/03
• Rifabutin Rescue Therapy Effective After Helicobacter Eradication Failures - Doctor's Guide, 4/16/03
• Omeprazole/Bismuth Biskalcitrate/Metronidazole/Tetracycline Combo Effective Helicobacter Pylori Metronidazole Resistance - Doctor's Guide, 4/11/03
• Antibiotic Combinations Only Partially Effective For Helicobacter Pylori - Doctor's Guide, 4/1/03
• Rabeprazole Plus Antibiotics Effectively Eradicates Helicobacter Pylori Infection - Doctor's Guide, 3/26/03
• Rabeprazole/ Levofloxacin/Rifabutin Therapy Equally Effective as Quadruple Therapy in Second-Line Treatment of Helicobacter Pylori - Doctor's Guide, 3/18/03
• Canada Approves Helcide, Single Capsule Triple Therapy For Eradication Of Helicobacter Pylori - Doctor's Guide, 3/18/03
• Peptic Ulcer Disease Patients Seem To Benefit More from Helicobacter Pylori Eradication Than Other Gastro Patients - Doctor's Guide, 2/5/03
• H. pylori Vaccine Approved as an Investigational New Drug - Medscape, 1/28/03
• Peptic Ulcer Disease Patients Should be Tested for H.Pylori before Treating the Infection - Doctor's Guide, 1/21/03
• New Protocol for H. pylori Urea Breath Test - Medscape, 1/10/03
• PPI Triple Therapy Almost as Effective as Quadruple Therapy Against H. pylori - Medscape, 12/20/02
• Levofloxacin Triple Therapy Best Eradicates Helicobacter Pylori - Doctor's Guide, 12/19/02
• Tetracycline Resistance in Helicobacter Pylori Requires Multiple Mutations - Doctor's Guide, 12/2/02
• Omeprazole Triple Therapy As First-Line Treatment For Helicobacter Pylori In Patients With Active Duodenal Ulcers - Doctor's Guide, 12/2/02
• First Seven-Day Treatment of H. Pylori Infection Approved by FDA - Doctor's Guide, 11/14/02
• H. Pylori Eradication After Five Years Follow-Up - Doctor's Guide, 10/31/02
• Helicobacter Pylori Antibiotic Resistance In Children - Doctor's Guide, 10/29/02
• H. Pylori Lessens Activity Of Class IV Alcohol Dehydrogenate In The Stomach Of Gastric Ulcer Patients - Doctor's Guide, 10/29/02
• National Survey Shows Primary Care Physicians Unclear on Treatment of Gastrointestinal Disorders - Doctor's Guide, 10/25/02
• Helicobacter Pylori Could Play Role In Familial Gastric Cancer - Doctor's Guide, 10/25/02
• H. pylori Therapy Not Necessary for Some Dyspepsia Patients - Doctor's Guide, 10/24/02
• H. Pylori Not Linked To Stomach Polyps In Inherited Polyposis - Doctor's Guide, 10/4/02
• Rheumatoid Arthritis May Improve After Helicobacter Pylori Eradication - Doctor's Guide, 8/29/02
• Infected Parents Key in Paediatric Transmission of Helicobacter Pylori - Doctor's Guide, 8/14/02
• Iron Metabolism and Serum Ferritin Levels Reduced in Children with Helicobacter Pylori Infection - Doctor's Guide, 8/12/02
• Impact Of Lactobacillus F19 On Intestinal Microflora In Children And The Elderly - Doctor's Guide, 7/26/02
• Role of Helicobacter Pylori Infection and Other Factors in Gastroduodenal Pathology - Doctor's Guide, 7/25/02
• Ulcer-Causing Bacteria Linked to Stroke - WebMD, 7/8/02 - "H. pylori causes ulcers in the stomach ... those who had suffered a stroke from a blocked large artery had significantly higher levels of the more potent strains of the bacteria ... The study also found that levels of a substance known as C-reactive protein (CRP) that indicates inflammation within the body were also higher in the stroke groups. But patients with the potent strains of H. pylori had the highest CRP levels ... treating patients with H. pylori infection may be an easy way to reduce the risk of stroke"
• Heartburn Drug [Prevacid] Can Let Some Heart Patients Take Aspirin - Intelihealth, 6/26/02
• Proton Pump Inhibitor Therapy Reduces Bioavailability of Dietary Vitamin C - Doctor's Guide, 5/20/02 - "The mean pre-treatment plasma vitamin C concentration in H. pylori -negative subjects was 25.1 mg/mL (range 16.1-33) and 17.4 mg/mL (6.7-29) in H. pylori-positive subjects (p<0.001). Mean daily dietary intake of vitamin C was 44 mg/day (range 10-130) in H. pylori positive subjects compared to 141 mg/day (range 23-282) negative subjects (p<0.001) ... Four week of omeprazole [Prilosec - the purple pill] treatment achieved reductions in mean plasma vitamin C concentrations of 15 percent (p=0.005) in H. pylori-positive and -negative subjects"
• Patients Awaiting Laparoscopic Cholecystectomy - Could Helicobacter pylori Be the Main Cause of the Symptoms? - Doctor's Guide, 5/20/02
• Breath Test As Effective As Endoscopy In H. Pylori Detection - Doctor's Guide, 4/25/02
• H. Pylori Eradication Reduced By Resistance To Commonly Used Antibiotics - Doctor's Guide, 4/12/02
• Ulcer Patients May Need Warning - Intelihealth, 10/24/01
• Researcher Focuses On Ulcer Germ - Intelihealth, 9/13/01
• Get Your ZZZs, Your Tummy Will Thank You, Natural Stomach Protein Repairs Damage, Protects Against Ulcers While You Sleep - WebMD, 5/9/01 - "late hours, too much alcohol, and other lifestyle factors that prevent a good night's sleep, disrupt the stomach's natural repair cycle and may lead to ulcers, or tearing of the stomach lining"
• Shorter Treatment Effective In Treating H. Pylori Stomach Ulcers - Doctor's Guide, 8/10/98
• Ulcer-Causing Bacteria Also May Be Associated With Heart Disease - Doctor's Guide, 5/4/98
• H. Pylori Linked To Stroke - Doctor's Guide, 2/9/98