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Radiation Therapy
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Evidence for
the use of curcumin in radioprotection and radiosensitization
- Phytother Res 2023 Mar 10 - "Curcumin
has antineoplastic properties and is considered a
chemotherapeutic and chemopreventive agent. Curcumin may be
associated with radiation therapy (RT) as a radiosensitizer for
cancer cells and a radioprotector for normal cells. In
principle, it may result in a reduction of RT dosage for the
same therapeutic effect on cancer cells, and further reduced
damage to normal cells. Though the overall level of evidence is
modest, limited to in vivo and in vitro experiences and
practically no clinical trials, as the risks of adverse effects
are extremely low, it is reasonable to promote the general
supplementation with curcumin during RT targeting the reduction
of side effects through anti-inflammatory mechanisms" -
See curcumin at Amazon.com.
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Lacticaseibacillus casei ATCC334 Ameliorates Radiation-Induced
Intestinal Injury in Rats by Targeting Microbes and Metabolites
- Mol Nutr Food Res 2022 Nov 21 - "These
results highlight that medium and high doses of L. casei ATCC334 alleviate
radiation-induced intestinal damage by enhancing the mucosal barrier and
remodeling the gut microbiota structure and metabolic activity" - See probiotic supplements at Amazon.com.
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Astaxanthin attenuates
irradiation-induced osteoporosis in mice by inhibiting oxidative stress,
osteocyte senescence, and SASP - Food Funct 2022 Oct 26 -
"Radiation therapy (RT) is a crucial part of many
treatment plans for cancer patients. However, major undesired side effects are
associated with this treatment, including impaired bone remodeling and bone
loss. Irradiation induces bone loss due to promoted osteoclastic bone resorption
and reduced osteoblastic bone formation. Astaxanthin (AST) is a natural
antioxidant with anti-oxidative and anti-aging properties ... Reduced BMD, bone
biomechanical strength, bone formation, elevated oxidative stress, and
osteoclast activity with microarchitectural deterioration of trabecular and
cortical bones were observed in IR mice. Supplementation with AST corrected
these osteoporotic phenotypes, caused by IR, by inhibiting oxidative stress, DNA
damage, osteocyte senescence, and senescence-associated secretory phenotype
(SASP), subsequently promoting osteoblastic bone formation and inhibiting
osteoclastic bone resorption. The results from our study provide experimental
evidence for the clinical use of AST to prevent IR-induced osteoporosis in
cancer patients" - See astaxanthin at Amazon.com.
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Potentialities of Ginkgo
extract on toxicants, toxins, and radiation: a critical review - Food Funct
2022 Jul 8 - "Exposure to toxins is a severe threat to
human health and life in today's developing and industrialized world. Therefore,
identifying a protective chemical could be valuable and fascinating in this
case. The purpose of this article was to bring together thorough review of
studies on Ginkgo biloba to aid in the creation of ways for delivering its
phytoconstituents to treat toxicants and radiation. This review gathered and
evaluated studies on the defensive impact of Ginkgo biloba extract (GBE) against
toxicities caused by toxic chemical agents (such as lead, cadmium, and
aluminum), natural toxins (for example, lipopolysaccharide-induced toxicity and
damage, gossypol, latadenes, and lotaustralin), and radiation (for example,
gamma, ultra-violet, and radio-frequency radiation). According to this review,
GBE has a considerable therapeutic effect by influencing specific
pathophysiological targets. Furthermore, GBE has antioxidant, anti-inflammatory,
anti-apoptotic, and antigenotoxicity properties against various toxicities.
These are due to flavone glycosides (primarily isorhamnetin, kaempferol, and
quercetin) and terpene trilactones (ginkgolides A, B, C, and bilobalide) that
aid GBEs' neutralizing effect against radiation and toxins by acting
independently or synergistically" - See
Ginkgo biloba at Amazon.com.
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L-arginine Enhances Effect
of Radiation on Brain Metastases - Medscape, 11/17/21 -
"63 patients with brain metastases related to solid
tumors — such as non-small cell lung cancer (51%), triple-negative breast cancer
(21%), and melanoma (8%) — were randomized to receive oral L-arginine 10 g or
placebo prior to each fraction of radiation. The whole-brain radiation therapy
protocol consisted of a total dose of 32.0 Gy, administered in 20 fractions,
followed by a boost of 22.4 Gy that adhered to the same fractionation schedule.
The investigators used the Fisher's exact test or the Cox-Mantel test to compare
responses ... The majority of patients had an uncontrolled primary tumor,
multiple metastatic sites, and multiple brain metastases. The median follow-up
after the end of the treatment was 5 months (range, 1 - 55 months) ...
L-arginine was well tolerated and did not produce short- or long-term (more than
6 months) adverse events. The overall response rate was significantly higher in
the L-arginine group than in the placebo group (77.4% vs 22.0%; P < .001), as
was the symptomatic response rate (93.5% vs 50.0%; P = .002) ... Complete
neurologic responses were three times more likely in patients pretreated with
L-arginine than in those pretreated with placebo, although the difference was
not significant (29.0% vs 9.4%; P = .059). And at 6 months, patients in the
L-arginine group were four times more likely to be free from neurologic
progression than patients in the placebo group (82.0% vs 20.0%; ... Median
overall progression-free survival was longer in the L-arginine group than in the
placebo group (5 vs 2 months" - See L-arginine products at Amazon.com.
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Arginine, an inexpensive oral drug, could enhance radiation therapy for cancer
- Science Daily, 11/6/21 - "Arginine, also called
L-arginine, is inexpensive and widely available, generally considered safe, and
can get relatively easily from the bloodstream into the brain. The idea of using
it to treat cancer arose from observations that tumors often aid their own
survival by producing high levels of the related molecule nitric oxide (NO). The
latter regulates multiple processes in the body including the flow of blood
through blood vessels, and tumors cells often make more NO by upregulating their
production of special enzymes called NO synthases, which synthesize NO from
arginine ... patients were treated with high-dose arginine or placebo oral
suspensions an hour before radiotherapy for their brain metastases -- tumors in
the brain that represent the spread from primary tumors elsewhere, such as the
lungs ... Six months after their courses of radiotherapy, 82 percent of the
arginine group had improvement, or at least no worsening, of their neurological
symptoms, compared with 20 percent in the placebo group. Most of the
arginine-treated patients who died during the study did so because of their
cancers' spread elsewhere in the body ... Moreover, although metastatic cancer
usually has a dire prognosis, there were some arginine-treated patients whose
tumors in and outside the brain disappeared, suggesting the possibility of
cures" - See L-arginine products at Amazon.com
and
L-arginine at iHerb.
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Radiosensitizing Effect of
Curcumin on Human Bladder Cancer Cell Lines: Impact on DNA Repair Mechanisms
- Nutr Cancer 2021 Oct 13 - "Chemo-radiotherapy is one
of the promising approaches to treat bladder cancer, but its effectiveness is
limited to sensitive patients. Polyphenol curcumin has shown anticancer and
radiosensitizing potentials, but the mechanism is not fully understood ...
curcumin treatment increased the radiosensitivity by modifying the DNA
double-strand breaks repair kinetics of the most radioresistant cells UM-UC6
without affecting the radiosensitive UM-UC5. Moreover, UM-UC6 cell survival and
proliferation was significantly decreased after the combination of curcumin with
radiation. Bladder cell migration was also inhibited considerably. Curcumin was
also shown to reduce the number and the volume of bladder cancer spheres of both
cell lines. This study revealed that curcumin was able to radiosensitize
resistant bladder cell line without affecting the sensitive one with minimal
side effects through enhancing DNA damage signaling and repair pathway" -
See curcumin at Amazon.com and
iHerb.
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Berberine-A potent
chemosensitizer and chemoprotector to conventional cancer therapies -
Phytother Res 2021 Feb 8 - "Chemotherapy and
radiotherapy are mainstay treatments for cancer patients. However, their
clinical outcomes are highly limited by the resistance of malignant tumors to
these therapies and the incurrence of serious damages in vital organs. This in
turn necessitates the development of adjunct drugs that overcomes chemo/radioresistance
in refractory cancers and protects vital organs from the cytotoxic effects of
cancer therapies. In recent years, Berberine (BBR), a natural isoquinoline
alkaloid has garnered more attention due to its potent chemosensitizing and
chemoprotective properties. BBR effectively sensitizes refractory cancers to
chemotherapy and radiotherapy by ameliorating the diverse events underlying
therapy resistance. Furthermore, it protects the heart, liver, lungs, and
kidneys from severe damages caused by these therapies. In this review, we
discuss the molecular mechanisms underlying the chemo/radiosensitizing and
chemo/radioprotective potential of BBR during cancer treatment." - See
berberine at Amazon.com.
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Resveratrol treatment may
preserve the erectile function after radiotherapy by restoring antioxidant
defence mechanisms, SIRT1 and NOS protein expressions - Int J Impot Res.
2018 Jul 5 - "Radiotherapy (RT) for prostate cancer (PC)
can cause erectile dysfunction (ED) by damaging neurovascular structures with
oxidative stress. In this study, we evaluated the effects of resveratrol, an
antioxidant, on post-RT ED. Fifty rats in five groups were evaluated; control
(C), prostate-confined radiotherapy with short- and long-term vehicle or
resveratrol treatment ... Radiotherapy caused a decrease in sirtuin-1, nNOS, and
eNOS protein expressions. These parameters were reversed by resveratrol
treatment ... Resveratrol preserved the metabolic pathways involved in erectile
function and provided functional protection. Resveratrol can be used as a
supplementary agent in patients undergoing radiotherapy to preserve erectile
function" - See
resveratrol products at Amazon.com.
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Pomegranate Intake
Protects Against Genomic Instability Induced by Medical X-rays In Vivo in Mice
- Nutr Cancer. 2016 Nov-Dec;68(8):1349-1356 - "Ionizing
radiation (IR) is a well-documented human carcinogen. The increased use of IR in
medical procedures has doubled the annual radiation dose and may increase cancer
risk. Genomic instability is an intermediate lesion in IR-induced cancer. We
examined whether pomegranate extract (PE) suppresses genomic instability induced
by x-rays ... glutathione (GSH) ... Thus, ingestion of pomegranate polyphenols
is associated with inhibition of x-ray-induced genomic instability and elevated
GSH, which may reduce cancer risk" - See
pomegranate extract at Amazon.com.
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Effect of Oral Silymarin
Administration on Prevention of Radiotherapy Induced Mucositis: A Randomized,
Double-Blinded, Placebo-Controlled Clinical Trial - Phytother Res. 2016 Aug
23 - "Mucositis is a frequent severe complication of
radiation therapy in patient with head and neck cancer ... oral silymarin 420 mg
daily in three divided doses starting at the first day of radiotherapy for
6 weeks, on oral mucositis occurrence was assessed ... The median World Health
Organization and National Cancer Institute Common Terminology Criteria scores
were significantly lower in silymarin group at the end of the first to sixth
week (p < 0.05). The scores increased significantly in both placebo and
silymarin groups during radiotherapy, but there was a delay for mucositis
development and progression in silymarin group. Prophylactic administration of
conventional form of silymarin tablets could significantly reduce the severity
of radiotherapy induced mucositis and delay its occurrence in patients with head
and neck cancer" - See
silymarin at Amazon.com.
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Modulation
of Radiation-Induced Alterations in Oxidative Stress and Cytokine Expression in
Lung Tissue by Panax Ginseng Extract - Phytother Res. 2014 Sep 15 -
"We investigated the modulating effect of Panax ginseng
extract (PGE) on radiation-induced lung injury (RILI) ... A high pretreatment
dose of PGE may be a useful pharmacological approach for protection against
RILI" - See
ginseng at Amazon.com.
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Antioxidant
supplementation has a positive effect on oxidative stress and hematological
toxicity during oncology treatment in cervical cancer patients - Support
Care Cancer. 2012 Dec 14 - "Hematological toxicity and
oxidative stress are common in cancer patients ... Randomized, single-blinded
controlled trial in women with cervical cancer treated with radiotherapy and
chemotherapy with cisplatin. Subjects were randomly assigned to receive
antioxidant supplement or placebo supplement ... At the end of the oncology
treatment, hemoglobin levels were maintained, and global QoL was better only in
the supplemented group ... Antioxidant supplementation in patients treated with
chemotherapy and radiotherapy apparently decreased oxidative stress, maintained
hemoglobin levels, and improved QoL" - See
Garden of Life, Radical Fruits Antioxidant Complex at Amazon.com.
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Probiotic protects intestine from radiation injury - Science Daily, 11/16/11
- "the therapy can kill both cancer cells and healthy
ones, leading to severe bouts of diarrhea if the lining of the intestine gets
damaged ... For many patients, this means radiation therapy must be
discontinued, or the radiation dose reduced, while the intestine heals ...
Probiotics may provide a way to protect the lining of the small intestine from
some of that damage ... the probiotic bacteria Lactobacillus rhamnosus GG (LGG),
among other Lactobacillus probiotic strains, protected the lining of the small
intestine in mice receiving radiation ... the probiotic was effective only if
given to mice before radiation exposure ... The bacteria we use is similar to
what's found in yogurt or in commercially available probiotics ... So
theoretically, there shouldn't be risk associated with this preventative
treatment strategy any more than there would be in a patient with abdominal
cancer eating yogurt" - See
probiotics at Amazon.com.
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Protective
Effect of Lycopene against Radiation-induced Hepatic Toxicity in Rats - J
Int Med Res. 2011;39(4):1239-52 - "Lycopene
supplementation significantly reduced radiotherapy-induced oxidative liver
injury" - See
lycopene at Amazon.com.
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Green Tea
Extract (Epigallocatechin-3-Gallate) Reduces Efficacy of Radiotherapy on
Prostate Cancer Cells - Urology. 2011 Jun 13 -
"Radiotherapy is effective in inducing apoptosis in DU145 cells, but its effect
was significantly reduced in the presence of EGCG, and this was associated with
an increase in the induction of manganese superoxide dismutase"
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Protective
Role of Tea Polyphenols in Combination against Radiation-induced Haematopoietic
and Biochemical Alterations in Mice - Phytother Res. 2011 Mar 31 -
"The purpose of this study was to investigate the
radioprotective effects of tea polyphenols (TPs) in various combinations against
radiation-induced damage in mice. Mice were divided into different groups:
non-irradiated control, irradiated control, amifostine (43.6 mg/kg, i.v. 30 min
before irradiation; positive control) and various combinations of tea
polyphenols in different doses. The radioprotective effect on the haematopoietic
system, serum cytokines and endogenous antioxidant enzymes were studied. TP50,
containing approximately 50% of (-)-epigallochatechin-3-gallate in addition to
other catechins, showed the greatest radioprotective effect against
radiation-induced changes in haematological parameters (red blood cell count,
white blood cell count and haemoglobin), and maintained the spleen and thymus
indices unchanged (spleen or thymus weight/body weight × 1000). Tea polyphenols
also significantly decreased radiation-induced lipid peroxidation
(malondialdehyde levels), elevated endogenous antioxidant enzymes (superoxide
dismutase) and reduced the serum cytokines which were elevated in
radiation-induced toxicity. This evidence shows the potential of tea
polyphenols, particularly in the combination found in TP50, as radioprotectors
in mice, especially regarding recovery of the haematopoietic system, antioxidant
potential activity and reduction of inflammatory cytokines"
- See
green tea extract at Amazon.com.
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Soy
increases radiation's ability to kill lung cancer cells, study shows -
Science Daily, 4/1/11 - "These natural soy isoflavones
can sensitize cancer cells to the effects of radiotherapy, by inhibiting
survival mechanisms which cancer cells activate to protect themselves ... At the
same time, soy isoflavones can also act as antioxidants in normal tissues, which
protect them against unintended damage from the radiotherapy ... soy isoflavones
increase killing of cancer cells by radiation via blocking DNA repair
mechanisms, which are turned on by the cancer cells to survive the damage caused
by radiation ... Researchers used a formulation consisting of the three main
isoflavones found in soybeans, including genistein, daidzein and glycitein ...
Previously, researchers had found that pure genistein demonstrated antitumor
activity in human NSCLC cell lines and enhanced the effects of EGFR-tyrosine
kinase inhibitors. This study showed that the soy mixture had an even greater
antitumor effect than pure genistein" - See
soy isoflavones at Amazon.com.
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Antioxidant formula prior to radiation exposure may prevent DNA injury, trial
suggests - Science Daily, 3/29/11 - "In what the
researchers say is the first clinical trial of its kind, as much as a 50 percent
reduction in DNA injury was observed after administering the formula prior to CT
scans"
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Vitamin
supplement use during breast cancer treatment and survival: a prospective cohort
study - Cancer Epidemiol Biomarkers Prev. 2010 Dec 21 -
"Antioxidants may protect normal cells from the
oxidative damage that occurs during radiotherapy and certain chemotherapy
regimens, however, the same mechanism could protect tumor cells and potentially
reduce effectiveness of cancer treatments ... Vitamin use shortly after breast
cancer diagnosis was associated with reduced mortality and recurrence risk,
adjusted for multiple lifestyle factors, sociodemographics, and known clinical
prognostic factors. Women who used antioxidants (vitamin E, vitamin C,
multivitamins) had 18% reduced mortality risk (hazard ratio (HR) = 0.82, 95%
confidence interval (CI): 0.65-1.02) and 22% reduced recurrence risk (HR = 0.78,
95% CI: 0.63-0.95). The inverse association was found regardless of whether
vitamin use was concurrent or non-concurrent with chemotherapy, but was only
present among patients who did not receive radiotherapy"
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High dietary
niacin intake is associated with decreased chromosome translocation frequency in
airline pilots - Br J Nutr. 2010 Oct 8:1-9 -
"Experimental studies suggest that B vitamins such as niacin, folate,
riboflavin, vitamin B6 and vitamin B12 may protect against DNA damage induced by
ionising radiation (IR) ... We observed a significant inverse association
between translocation frequency and dietary intake of niacin (P = 0.02):
adjusted rate ratio for subjects in the highest tertile compared with the lowest
tertile was 0.58 (95 % CI 0.40, 0.83). Translocation frequency was not
associated with total niacin intake from food and supplements as well as dietary
or total intake of folate, riboflavin or vitamin B6 or B12. However, the
adjusted rate ratios were significant for subjects with ≥ median compared with <
median intake of whole grains (P = 0.03) and red and processed meat (P = 0.01):
0.69 (95 % CI 0.50, 0.96) and 1.56 (95 % CI 1.13, 2.16), respectively. Our data
suggest that a high intake of niacin from food or a diet high in whole grains
but low in red and processed meat may protect against cumulative DNA damage in
IR-exposed persons"
-
Airplane Radiation Exposure Protection - "During
a cross country flight from NY to LA you are subjected to more radiation
from the plane then you are during a chest X-ray" - Note:. Think
about it, if a pilot were to average two round trips per week (very
reasonable), that's 4 chest x-rays per week or 208 chest x-rays per year.
-
Soy
isoflavones in conjunction with radiation therapy in patients with prostate
cancer - Nutr Cancer. 2010 Oct;62(7):996-1000 - "Soy
isoflavones sensitize prostate cancer cells to radiation therapy by inhibiting
cell survival pathways activated by radiation. At the same time, soy isoflavones
have significant antioxidant and anti-inflammatory activity, which may help
prevent the side effects of radiation ... Adverse effects of radiation therapy
on bladder, bowel, and sexual function were assessed by a self-administered
quality of life questionnaire at 3 and 6 mo. Only 26 and 27 patients returned
completed questionnaires at 3 and 6 mo, respectively. At each time point,
urinary, bowel, and sexual adverse symptoms induced by radiation therapy were
decreased in the soy isoflavone group compared to placebo group. At 3 mo,
soy-treated patients had less urinary incontinence, less urgency, and better
erectile function as compared to the placebo group. At 6 mo, the symptoms in
soy-treated patients were further improved as compared to the placebo group.
These patients had less dripping/leakage of urine (7.7% in Group 1 vs. 28.4% in
Group 2), less rectal cramping/diarrhea (7.7% vs. 21.4%), and less pain with
bowel movements (0% vs. 14.8%) than placebo-treated patients. There was also a
higher overall ability to have erections (77% vs. 57.1%). The results suggest
that soy isoflavones taken in conjunction with radiation therapy could reduce
the urinary, intestinal, and sexual adverse effects in patients with prostate
cancer" - See
soy isoflavones at Amazon.com.
-
Lycopene in
the prevention of gastrointestinal toxicity of radiotherapy - Nutr Cancer.
2009 Nov;61(6):784-8 - "The rats receiving RT only had
significantly higher weight loss rate compared to the lycopene plus RT group (P
= 0.001). Plasma TBARS levels after RT were also significantly higher in the RT
only group compared to lycopene plus RT group (P = 0.001). In conclusion,
lycopene supplementation significantly reduced the weight loss and prevented
oxidative stress in rats treated with abdominopelvic radiation" - See
lycopene at Amazon.com.
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Herbal Tonic For Radiotherapy? Gingko Biloba Tree May Protect Cells From
Radiation Damage - Science Daily, 10/26/09 -
"They found that there was a significant increase in apoptosis in the
untreated cells compared with those treated with G. biloba extract. Almost a
third of the untreated cells underwent apoptosis compared with approximately
one in twenty of the treated cells. Parallel studies with laboratory mice
also demonstrated a similar protective effect against radiation poisoning"
- See
Ginkgo biloba at Amazon.com.
-
Could Vitamin D Save Us From Radiation? - Science Daily, 11/7/08 -
"calcitriol, the active form of vitamin D, may
protect us from background radiation and could be used as a safe protective
agent before or after a low-level nuclear incident" - See
vitamin D at Amazon.com.
-
Plant Antioxidant May Protect Against Radiation Exposure - Science
Daily, 9/23/08 - "Resveratrol, the natural
antioxidant commonly found in red wine and many plants, may offer protection
against radiation exposure ... Currently there are no drugs on the market
that protect against or counteract radiation exposure"
-
Antioxidant Supplements May Lessen Benefit Of Radiation And Chemotherapy
- Science Daily, 5/27/08
-
Antioxidants Could Provide All-purpose Radiation Protection - Science
Daily, 11/5/07 - "Inositol and inositol
hexaphosphate (IP6) protected both human skin cells and a skin cancer-prone
mouse from exposure to ultraviolet B (UVB) radiation, the damaging radiation
found in sunlight ... Twenty-three percent of treated mice developed tumors,
compared to 51 percent of untreated, or control mice, which developed
tumors. Moreover, the mice in the treated group that did develop cancer had
only half as many tumors as the control mice" - See
IP-6 products at Amazon.com. Note: IP-6 was one
of the supplements I took when they told me I only had a small chance of
survival from neck cancer.
Click here for the full story. I
still take it.
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Vitamin E: Friend or Foe During Radiation Therapy? - Physician's Weekly,
7/16/07 - "Not only did it show that vitamin E
supplementation was of no benefit to patients, but it was also associated
with a nearly 40% increased risk of death when compared to study
counterparts who received a placebo. Vitamin E, despite what patients may
think, appears to be much more harmful for patients who have head and neck
cancer who are receiving radiation therapy"
-
Tea
Extracts Help Treat Damaged Skin In Cancer Patients - Science Daily,
11/1/06 - "tea extracts reduce the duration of
radiation-induced skin damage by up to 10 days in patients who received
radiation treatment"
-
Research Finds Antioxidant Therapies Do Not Interfere With Radiation
Treatment - Science Daily, 11/12/06 -
"Radiation Therapy for Prostate Cancer, was
conducted by researchers ... Researchers found no difference between
patients taking antioxidants and those who did not. Antioxidants used in the
study included green tea extract, melatonin, high-potency multivitamins,
vitamin C and vitamin E"
- Are Antioxidants
Safe During Chemotherapy and Radiation Treatment? - Healthwell Exchange
Daily News, 9/29/05
-
Antioxidants may hamper cancer therapies - Nutra USA, 9/22/05 -
"there are some indications that antioxidants can
actually be harmful for patients being treated with chemotherapy or
radiotherapy, since they may be unable to differentiate between normal cells
and cancer cells. This may mean that treatment is rendered less effective"
- Phytoestrogens and
Antioxidants - Medscape, 1/26/05 -
"What if exogenous antioxidants also protect the
tumor? Should physicians, and in particular radiotherapists, advise against
their use for patients undergoing radiation treatments? Or should they,
instead, recommend them to prevent damage to normal tissues associated with
treatment? ... No significant difference was seen in the amount of radiation
required for tumor control between mice receiving antioxidants in their diet
and control animals. There was, however, a trend toward a slightly higher
dose needed for tumor eradication in antioxidant-treated mice. On the other
hand, there was a significant difference in the damages induced by radiation
treatment in the 2 groups: Vitamin E and GTE-treated mice showed partial
protection of normal tissues from radiation injury"
- Exercise
Fights Fatigue of Radiation Therapy - WebMD, 8/4/04
- Vitamin E Prevents
Painful Radiation Therapy Side Effect - Healthwell Exchange Daily News,
6/10/04
- Treatment for a
Serious Side Effect: Vitamin E Improves Radiation Damage - Healthwell
Exchange Daily News, 4/15/04
- Natural Relief for
Radiation Burns? - Dr. Weil, 1/29/04
-
Vitamin D May Augment Breast Cancer Treatments - Physician's Weekly,
5/19/03 -
"treatment with vitamin D
was three times more effective in preventing new tumor growth when compared
to radiation therapy alone"
- Curry Spice Takes
Burn Out of Radiation - WebMD, 10/10/02 -
"The study showed that
curcumin, the substance in turmeric that gives it and the dishes it
flavors a characteristic yellow color, is a natural anti-inflammatory
compound. It works in ways similar to the popular Cox-2 inhibiting drugs,
including aspirin and Celebrex"- - See
curcumin supplements at Amazon.com.
- In Praise of Spirulina
- CancerDecisions.com, 12/12/02 -
"Spirulina also shows
potential for decreasing the adverse effects of both
chemotherapy and radiation"
-
Oral Enzyme Therapy Reduces Radiation-Related Side Effects In Cervical
Cancer - Doctor's Guide, 11/28/01 - See enzymes
-
Antioxidants Resolve Radiation Side Effects - Nutrition Science News,
9/01
Other News:
-
MRI
contrast agents accumulate in the brain - Science Daily, 8/7/17
-
Expert
opinion: Are CT scans safe? - Science Daily, 10/6/15 -
"Areas that have higher background radiation levels
(e.g., from the sun and radon in the ground) have lower cancer rates. If there
is a cause and effect, it's simply too small to measure. And, because of
increased research and updates in technology, less radiation also is used these
days in medical imaging"
-
DNA
damage seen in patients undergoing CT scanning, study finds - Science Daily,
7/22/15 - "A CT scan, which is used for imaging and
diagnostic procedures throughout the body, exposes patients to at least 150
times the amount of radiation from a single chest X-ray ... Researchers
examined the blood of 67 patients undergoing cardiac CT angiograms ...
Results showed an increase in DNA damage and cell death, as well as
increased expression of genes involved in cell repair and death ... Although
most cells damaged by the scan were repaired, a small percentage of the
cells died ... radiation exposure from cardiac CT angiography may cause DNA
damage that can lead to mutations if damaged cells are not repaired or
eliminated properly ... It is important to note that we did not detect any
DNA damage in patients receiving the lowest doses of radiation and who were
of average weight and had regular heart rates"
-
How much does an MRI cost? Good luck finding out - nbcnews.com, 12/10/12
- "Blue Cross plan for my MRI: $600 for the MRI
without the contrast dye, and $1,200 for the MRI with the dye is its
negotiated rate with my health plan"
-
Breast cancer risk estimates increased with repeated prior CT and nuclear
imaging - Science Daily, 11/27/12 - "Young women
receiving several chest and or cardiac CTs had the greatest increased risk
of developing breast cancer at approximately 20 percent ... A 15-year-old
girl with no risk factors for breast cancer would double her 10-year risk of
developing breast cancer at 25"
-
Child Cancer Radiation Raises Breast Cancer Risk - WebMD, 6/4/12
-
Cancer risk from medical radiation may have been overestimated - Science
Daily, 12/1/10
-
Radiation risk from flying trumps body scanners - MSNBC, 11/24/10 -
"what's often overlooked is that flying itself
dwarfs the radiation doses delivered by the new body scanners ... You'd get
as much radiation in a whole-body scanner as you'd get in two minutes at
30,000 feet ... And with that designation, they should be educated and
monitored appropriately, much like doctors who routinely deliver X-rays and
cancer treatments ... As our sun enters a new phase of activity in its
11-year-or-so cycle, the risks of flying may be rising"
-
`Fed Up' Travelers, Unions Balk at Airport Body Scans - Bloomberg,
11/17/10 - "You would need 1,000 or 2,000 airport
scans just to equal one dental X-ray"
-
How Much Radiation Do You Get From Dental X-Rays? - Idaho State
University - "A typical dental x-ray image
exposes you to only about 2 or 3 mrem ... about 5 mrem for one
cross-country flight because of the increased altitude" - It's
something to consider, every time you fly across the United States you
get the equivalent of about two dental x-rays.
-
Risk
of cancer due to radiation exposure in middle age may be higher than
previously estimated - Science Daily, 10/25/10
-
Radiation after mastectomy underused, study finds - Science Daily,
3/29/10
-
Most
early-stage breast cancer patients may not need radiation after mastectomy
- Science Daily, 3/6/10
-
Long
waits for radiotherapy linked to increased recurrence of breast cancer -
Science Daily, 3/2/10
-
Airport full-body scanners expose passengers to less harmful radiation than
most flights, experts say - Science Daily, 1/7/10 -
"An airline passenger flying cross-country is
exposed to more radiation from the flight than from screening by one of
these devices"
-
Study:
15,000 will die from CT scans done in 1 year - Cancer- msnbc.com -
12/14/09 -
"Radiation from CT scans done in 2007 will cause
29,000 cancers and kill nearly 15,000 Americans ... What we learned is there
is a significant amount of radiation with these CT scans, more than what we
thought, and there is a significant number of cancers" - Also see
Are CT Scans Sometimes Too Risky? - WebMD, 12/14/09
-
How
Low Doses Of Radiation Can Cause Heart Disease And Stroke - Science
Daily, 10/22/09 - "If the mechanism is valid it
implies that risks from low dose radiation exposures (e.g., medical and
dental X-rays), which until now have been assumed to result only from
cancer, may have been substantially underestimated"
-
'Holy Grail' Of Cancer Therapy: Researchers Find Way To Protect Healthy
Cells From Radiation Damage - Science Daily, 10/21/09
-
PET/CT Scans May Help Detect Recurring Prostate Cancer Earlier - Science
Daily, 9/1/09
-
How
Safe Or Unsafe Are Medical Imaging Procedures? - Science Daily, 8/27/09
-
Too Much Radiation From Medical Imaging? - WebMD, 8/26/09
-
Radiation Therapy May Increase Diabetes Risk In Childhood Cancer Survivors
- Science Daily, 8/11/09
-
New
Pill May Prevent Injury After Radiation Exposure - Science Daily,
7/10/09
-
Reducing Patient Radiation Dose During Pulmonary CT Angiography -
Science Daily, 6/30/09
-
New
MRI Technique Could Mean Fewer Breast Biopsies In High-risk Women -
Science Daily, 6/29/09
-
Radiation Dose Drastically Reduced During Whole Chest MDCT - Science
Daily, 6/23/09
-
Lithium May Help Radiation Target Cancer, Spare Healthy Tissue - Science
Daily, 5/4/09
-
Majority Of Ordering Physicians Lack Knowledge Of Radiation Exposure Risks
From CT - Science Daily, 4/30/09
-
Experimental Agents May Prevent Radiation-induced Leukemia - Science
Daily, 4/19/09
-
Some
Radiation Therapy Treatments Can Decrease Fertility - Science Daily,
4/1/09
-
Multiple CT Scans Raise Cancer Risk - WebMD, 3/31/09
-
Study: Proton Beam Radiation Therapy May Cut Risk of Second Cancer -
WebMD, 9/22/08
-
New
Therapy Shows Promise For Fighting Treatment-resistant Cancer Cells -
Science Daily, 6/18/08
-
Speedier Precise Cancer Radiotherapy Now Available - Science Daily,
5/7/08
-
Trimming Breast Cancer Radiation Time - WebMD, 3/18/08
-
Over
20 Million People Unnecessarily Exposed To Radiation From CT Scans Each
Year, Study Suggests - Science Daily, 11/28/07
-
It kills thyroid cancer, but is radiation safe? - USATODAY.com, 11/19/07
-
Study Estimates Cancer Risk From Radiation Exposure During Cardiac CT Scans
- Science Daily, 7/18/07
-
Radiation for Breast Cancer Not Likely to Increase Heart Attack Risk -
Doctor's Guide, 5/7/07
-
Diabetes Drug [Actos® (pioglitazone)] Shows Promise For Preventing Brain
Injury From Radiation Therapy - Science Daily, 1/12/07 -
"the diabetes drug pioglitazone prevents
inflammation. The drug activates a specific type of peroxisome
proliferator-activated receptors (PPARs) that control fat and glucose
metabolism, and may be involved in inflammation"
-
Childhood Cancer Survivors Treated With Radiation Face Increased Risk Of
Tumors Later In Life - Science Daily, 11/13/06
-
Radiation Treatment: Myths Persist - WebMD, 11/7/06
-
Radiation Increases Risk Of Second Primary Tumors For Childhood Survivors
- Science Daily, 11/1/06
-
Proton Treatment Could Replace X-ray Use In Radiation Therapy - Science
Daily, 9/13/06
-
Loss of Memory and Concentration Common in Cancer Patients Undergoing
Chemotherapy or Radiation - Doctor's Guide, 6/7/06
-
Drug
Helps Cognitive Function In Brain Tumor Patients After Radiation -
Science Daily, 3/18/06
-
Think Twice Before Exercising When Getting That PET Scan - Science
Daily, 3/9/06
-
Even Mild Muscle Activity Impacts Positron Emission Tomography Results -
Doctor's Guide, 3/8/06
-
Shorter Radiation for Breast Cancer - WebMD, 1/4/06
-
FDA Clears Xoft's Axxent Electronic Brachytherapy System for Treatment of
Breast Cancer - Doctor's Guide, 1/4/06
-
Radiation may raise hip fracture risk in women - MSNBC, 11/22/05
-
Even
Low Exposure To X-rays, Gamma Rays Increases Cancer Risk, Study Finds -
Science Daily, 10/27/05
-
Patients May Want To Skip That Cup Of Coffee Before Undergoing PET/CT Scans
- Science Daily, 6/21/05
-
Radiation Therapy for Prostate Cancer Nearly Doubles Risk for Rectal Cancer
- Doctor's Guide, 4/1/05
-
Breast Cancer Radiation Has Become Safer - WebMD, 3/15/05
-
Whole-Body Computed Tomography Screening Costs Overshadow Benefits -
Doctor's Guide, 1/25/05
- Focused
Breast-Cancer Radiation Effective - WebMD, 8/19/03
-
Trend in Omitting Radiation Therapy in Breast Cancer Patients Exponentially
Increases Relative Mortality Risk - Doctor's Guide, 7/3/03
-
Young Radiation-Exposed Cancer Survivors at Risk for Non-Melanoma Skin
Cancer - Doctor's Guide, 6/4/03
-
Concurrent Chemo-Radiation Improves Survival in Stage Three Non-Small Cell
Lung Cancer - Doctor's Guide, 6/2/03
-
Patients Not Told About Risks, Benefits of Radiology Procedures -
Doctor's Guide, 5/5/03
-
Avoid Post-Surgical Radiotherapy for Non-Secreting Pituitary Adenomas -
Doctor's Guide, 4/28/03
-
Accelerated Radiation Treatment For Early Stage Breast Cancer Into Clinical
Settings - Doctor's Guide, 4/16/03
- Cancer
Treatment Shrinks Tumors Faster - WebMD, 2/28/03
-
Chemotherapy Followed By Radiotherapy Gives Excellent In-Field Control In
Hodgkin's Disease - Doctor's Guide, 1/7/03
-
Abdominal CT Dose Can Be Cut in Half for "Thinner" Patients, A New Study
Indicates - Doctor's Guide, 11/18/02
-
Haemoglobin And Quality Of Life For Cancer Patients Can Improve With
Erythropoietin - Doctor's Guide, 10/21/02
-
Photodynamic Therapy Useful in Breast Cancer Patients That Have Reached
Radiation Dose Limits - Doctor's Guide, 10/10/02
-
Prophylactic Alpha-Blockers Reduce Urinary Morbidity after Prostate
Brachytherapy - Doctor's Guide, 10/9/02
-
Radiation Reduces Risk of Recurrence in Node-Positive Mastectomy Patients
- Doctor's Guide, 10/9/02
-
Once-daily Kytril (Granisetron) Most Effective for Nausea in Abdominal
Radiation Therapy - Doctor's Guide, 10/9/02
-
Characteristics of Breast Cancers Missed by Magnetic Resonance Imaging -
Doctor's Guide, 9/9/02
-
Paclitaxel with Concurrent Radiation and Androgen Ablation Investigated for
Recurrent or Locally Advanced Prostate Cancer - Doctor's Guide, 5/21/02
-
Breast Cancer Radiation Doses Once Considered Safe Cause Later Problems
- Doctor's Guide, 5/16/02
- Radiation Damage
Lasts Through Generations - WebMD, 5/10/02
-
Mutations Can Carry Over Generations - Intelihealth, 5/7/02
- High-Dose Radiation
Treatment Effective At Fighting Some Cancers In Children - Doctor's
Guide, 12/13/01
- Laser-Induced
Thermotherapy Destroys Cancer Metastases, Relieves Pain - Doctor's
Guide, 11/29/01
- Radiofrequency Energy
Kills Kidney Cancers, Prevents Early Recurrence - Doctor's Guide,
11/28/01
- Studies Suggest Role for
Brachytherapy after Lumpectomy - Doctor's Guide, 11/27/01
-
Lab Tests Show That Tiny 'Smart Bomb' Can Invade And Kill Cancer Cells With
Radiation - Intelihealth, 11/15/01
- Novel
Chemotherapy/Radiation Regimen Improves Outlook in Early-Stage Hodgkin’s
Disease - Doctor's Guide, 11/14/01
- Tamoxifen and Radiation
Therapy Lowers Relapse in Breast Cancer Patients - Doctor's Guide,
11/7/01
- Hormone Therapy with High
Dose Radiation Improves Prostate Cancer Outcome - Doctor's Guide,
11/7/01
- Radiation Effective In
Treating In-Stent Restenosis - Doctor's Guide, 11/7/01
- Booster Radiation
Cuts Chance of Breast Cancer Coming Back - WebMD, 11/7/01
- Brachytherapy Shows More
Side Effects Than External Radiation in Prostate Cancer - Doctor's
Guide, 11/6/01
- Radiation Doesn't Help
Hodgkin's Lymphoma Patients Who Are In Remission - Doctor's Guide,
11/6/01
- Positron Emission
Tomography Scan Results in Management Changes for Majority of Breast Cancer
Patients - Doctor's Guide, 9/4/01
- Early Radiation Therapy
After Prostatectomy May Reduce Cancer Recurrence - Doctor's Guide,
6/4/01
- No Extra Benefit With
Radiation For Intermediate Stage Endometrial Cancer - Doctor's Guide,
6/4/01
- More Precise 3D Radiation
Yields Fewer Side Effects For Prostate Cancer Patients - Doctor's Guide,
5/14/01
- Some Children May Be
Getting Too Much Radiation From Computed Tomography Scans - Doctor's
Guide, 1/22/01
- Radiation Safe, Effective
For Breast Cancer Patients With BRCA1, BRCA2 Mutations - Doctor's Guide,
9/29/00
- Patients With Prostate
Cancer Live Longer With Radiation Therapy - Doctor's Guide, 7/17/00
- Chemoradiation Improves
Curative Resection Rates In Rectal Adenocarcinoma - Doctor's Guide,
6/27/00
- Better Response Rate With
Irinotecan + 5-FU + Irradiation In Rectal Cancer Patients - Doctor's
Guide, 6/27/00
- Radiation, Hormones Reduce
Breast Cancer Recurrence - Doctor's Guide, 5/23/00
- Higher doses of radiation
better than expected for early prostate cancer - Doctor's Guide, 5/1/00
- Beta Radiation May Prevent
Repeat Heart Blockages After Angioplasty - Doctor's Guide, 4/5/00
- Beta Radiation Seeds
Reduce In-stent Restenosis - Doctor's Guide, 3/14/00
- Increased Radiation For
Prostate Cancer Increases Cure Rate - Doctor's Guide, 3/1/00
- Rest Periods Help Prevent
Nerve Damage During Tumor Treatment - Doctor's Guide, 12/8/99
- RSR13 Plus Radiotherapy
Improves Brain Cancer Survival - Doctor's Guide, 11/5/99
- Amifostine Saves Salivary
Glands During Radiation Treatment - Doctor's Guide, 11/2/99
- Chemotherapy Plus
Radiation Increases Survival In Some Head And Neck Cancer Patients -
Doctor's Guide, 11/1/99
- New Radiation Treatment
For Large Tumors - Doctor's Guide, 9/30/99
- Kytril Approved For The
Prevention Of Radiation-Induced Nausea And Vomiting - Doctor's Guide,
7/29/99
- FDA Approves Ethyol To
Reduce Radiation-Induced Dry Mouth - Doctor's Guide, 6/25/99
- FDA Panel Recommends
Ethyol For Radiation-Induced Xerostomia - Doctor's Guide, 6/9/99
- Adding Chemotherapy To
Radiation Therapy Increases Cervical Cancer Survival - Doctor's Guide,
3/22/99
- Radiation + Cisplatin +
5-Fluorouracil Achieves Better Survival In Cervical Cancer Patients -
Doctor's Guide, 2/24/99
- Cervical Cancer Mortality
Rate Cut In Half By Radiation Plus Cisplatin - Doctor's Guide, 2/23/99
- Adding Two Chemotherapy
Agents To Radiation Improves Cervical Cancer Survival - Doctor's Guide,
2/23/99
- NCI Says Chemotherapy Plus
Radiation Improves Cervical Cancer Survival - Doctor's Guide, 2/22/99
- New Radiation/Chemotherapy
Regimen Improves Lung Cancer Survival - Doctor's Guide, 2/3/99
- Radiation Therapy Offers
Hope To Patients With Blindness - Doctor's Guide, 12/3/98
- Radiation Therapy Technique
May Improve Prostate Cancer Survival - Doctor's Guide, 12/1/98
- Hormonal Treatment With
Radiation Effective In Prostate Cancer - Doctor's Guide, 10/26/98
- Higher Doses Of Radiation
Are Tolerated - Doctor's Guide, 10/21/98
- Radiation Offers Better
Prognosis After Brain Cancer Surgery - Doctor's Guide, 11/3/98
- New Radiation Procedure
Targets Liver Cancer - Doctor's Guide, 6/1/98
- Ethyol Reduces Radiation
Side Effects In Head And Neck Cancer - Doctor's Guide, 5/19/98
- Combination Of Radiation
Therapy Tools Advances The Fight Against Cancer - Doctor's Guide,
12/1/97
- Innovative Device Helps
Reduce Radiation Exposure - Doctor's Guide, 11/27/97
- Paternal Irradiation Not
Linked To Childhood Leukemia - Doctor's Guide, 11/7/97
- New Cancer Treatments May
Improve Survival Rates, Reduce Radiation Side Effects - Doctor's Guide,
11/6/97
- Radiation Technique Offers
Alternative To Surgery For Brain Tumours - Doctor's Guide, 11/4/97
- Melanoma Can Be Treated
With Radiation, Study Suggests - Doctor's Guide, 10/6/97
- Radiotherapy For Lung
Cancer -- Little And Often Is The Answer - Doctor's Guide, 7/18/97
- Radiation Oncology Center
Launches Breakthrough Cancer Treatment - Doctor's Guide, 3/27/97
- Radiation As Effective as
Surgery for Early Stage Prostate Cancer - Doctor's Guide, 10/29/96
- Beth Israel Reports Benefits
of Chemotherapy Given Before Radiation - Doctor's Guide, 5/22/96
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