Home > Health Conditions > Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome (IBS)

Popular Medications:

•  Zelmac (tegaserod) / Effexor

Popular Supplement:

• NutraFlora® FOS / artichoke extract / acidophilus / fiber / enzymes / peppermint / chamomile / valerian / arabinogalactan / evening primrose oil

Alternative News:

• Human Milk Oligosaccharides Support Normal Bowel Function and Improve Symptoms of Irritable Bowel Syndrome: A Multicenter, Open-Label Trial - Clin Transl Gastroenterol 2020 Dec;11 - "Patients received daily orally administrated 5-g intervention of the HMOs 2'-fucosyllactose and lacto-N-neotetraose in a 4:1 mix ... Patients had a significant improvement from baseline to 12 weeks in total percentage of bowel movements with abnormal stool consistency (mean and [95% confidence interval]: 90.7 [88.9–92.9] vs 57.2% [53.9–60.5], P < 0.0001), overall IBS Symptom Severity Score (323 [314–332] vs 144 [133–155], P < 0.0001) and health-rela,ted quality of life (50.4 [48.0–52.8] vs 74.6 [72.3–76.9], P < 0.0001). Improvement was similar across IBS subtypes. Symptoms improved most in the first 4 weeks of intervention. The most common side effects were mild gastrointestinal symptoms such as flatulence, abdominal pain and discomfort, and distension" -  [Nutra USA] - See human milk oligosaccharides at Amazon.com.
• Vitamin D supplements could ease painful IBS symptoms - Science Daily, 1/25/18 - "IBS -- a condition which affects two in 10 people in the UK ... The study showed a high prevalence of vitamin D deficiency in IBS patients -- regardless of their ethnicity ... IBS accounts for 10 per cent of visits to GP surgeries and the condition has a significant and escalating burden on society as a consequence of lost work days and time spent on regular hospital appointments " - See vitamin D at Amazon.com.
• Homemade Yogurt Resolves Irritable Bowel Symptoms - Medscape, 12/7/17 - "We had 189 patients in the study, and 169 had remission within 6 months ... And some of the participants had lived with symptoms of irritable bowel syndrome for 9 or 10 years ... Complete remission — defined as the relief of pre-existing irritable bowel syndrome symptoms and one or two normal bowel movements daily — was achieved by 89% of the study participants" - Note:  I've had yogurt made the way indicated in this article many times made by different people.  It's not palatable.   Try the recipe on my yogurt page.
• Probiotic use linked to improved symptoms of depression - Science Daily, 5/23/17 - "twice as many adults with irritable bowel syndrome (IBS) reported improvements from co-existing depression when they took a specific probiotic than adults with IBS who took a placebo ... The study provides further evidence of the microbiota environment in the intestines being in direct communication with the brain" - [Abstract] [Nutra USA] - See probiotic products at Amazon.com.
• Symbiotics in irritable bowel syndrome - better than probiotics alone? - Curr Opin Clin Nutr Metab Care. 2015 Jun 23 - "Probiotics appear to be beneficial in IBS. Data supporting the use of symbiotics is sparse. Whether symbiotics are superior to probiotics is unclear"
• Effect of Probiotics on Irritable Bowel Syndrome - Medscape, 1/27/14 - "Patients were randomly assigned to two groups: either to receive multispecies probiotics (a mixture of Bifidobacterium longum, B. bifidum, B. lactis, Lactobacillus acidophilus, L. rhamnosus, and Streptococcus thermophilus ) twice a day for 4 weeks or to receive a placebo twice a day for 4 weeks ... The proportion of patients whose IBS symptoms were substantially relieved at week 4 was significantly higher in the probiotics group than in the placebo group: 68.0% (17/25) versus 37.5% (9/24) (P < 0.05). Secondary end-points such as improvement in abdominal pain/discomfort and bloating occurred in the probiotics group but not in the placebo group" - See probiotic products at Amazon.com.
• Probiotics reduce stress-induced intestinal flare-ups, study finds - Science Daily, 3/14/13 - "while stress does not cause IBS, it does alter brain-gut interactions and induces the intestinal inflammation that often leads to severe or chronic belly pain, loss of appetite and diarrhea ... Stress has a way of suppressing an important component called an inflammasome which is needed to maintain normal gut microbiota, but probiotics reversed the effect in animal models ... The effect of stress could be protected with probiotics which reversed the inhibition of the inflammasome" - See probiotic products at Amazon.com.
• Probiotics and prebiotics in the management of irritable bowel syndrome: a review of recent clinical trials and systematic reviews - Curr Opin Clin Nutr Metab Care. 2011 Sep 1 - "Most systematic reviews indicate that probiotics have a beneficial impact on global IBS symptoms, abdominal pain and flatulence. However, recent trials indicate that different probiotics can improve, have no effect, or even worsen symptoms, confirming that benefits are likely to be strain and symptom-specific. There are no recent clinical trials of prebiotics in IBS, although previous studies indicate potential benefit at lower doses ... Clearly, some probiotics have considerable potential in the management of IBS; however, the benefits are likely to be strain-specific. Preliminary studies suggest low doses of prebiotics may improve symptoms of IBS, although further robust clinical trials are required" - See probiotics at Amazon.com.
• Probiotics may ease bloating for people with bowel disorders: Study - Nutra USA, 5/12/11 - "Compared to results at the start and end of the study, bloating symptoms were reduced by 15 percent in the probiotic group"
• How peppermint helps to relieve irritable bowel syndrome - Science Daily, 4/19/11 - "peppermint acts through a specific anti-pain channel called TRPM8 to reduce pain sensing fibres, particularly those activated by mustard and chilli. This is potentially the first step in determining a new type of mainstream clinical treatment for Irritable Bowel Syndrome (IBS)" - See peppermint products at iHerb.
• Exercise improve symptoms in irritable bowel syndrome - Science Daily, 1/25/11
• Probiotics again show potential for IBS relief - Nutra USA, 5/21/10
• Psyllium Fiber Helps IBS - WebMD, 8/28/09
• Prebiotic may offer ray of light for IBS sufferers: Study - Nutra USA, 1/19/09
• Peppermint Oil, Fiber Can Treat IBS - WebMD, 11/13/08
• Probiotics May Relieve Symptoms of Irritable Bowel Syndrome - Medscape, 3/20/09 - "In patients with IBS, probiotics showed a modest improvement in overall symptoms, using both dichotomous and continuous data"
• Efficacy of Probiotics in Irritable Bowel Syndrome: A Meta-Analysis of Randomized, Controlled Trials - Dis Colon Rectum. 2008 May 9 - "Pooling of eight trials for the outcome of clinical improvement yielded a significant relative risk of 1.22 ... Probiotics may improve symptoms of irritable bowel syndrome and can be used as supplement to standard therapy" - See probiotics at Amazon.com.
• Clinical trial: multispecies probiotic supplementation alleviates the symptoms of IBS and stabilises intestinal microbiota - Aliment Pharmacol Ther. 2007 Oct 6 - "The composite IBS score had at five months decreased 14 points (95% CI: -19 to -9) from baseline with the multispecies probiotic versus 3 points (95% CI: -8 to 1) with placebo (p=0.0083). Especially distension and abdominal pain were affected" - See probiotics at Amazon.com.
• Elderly 'should take probiotics' - BBC News, 8/7/06 - "the drinks, yoghurts or capsules could help protect older people against bowel conditions, such as Irritable Bowel Syndrome (IBS)" - See iHerb probiotics.
• Hypnotherapy Improves Quality Of Life For People With Irritable Bowel Syndrome - Science Daily, 5/30/06
• Irritable Bowel Syndrome: Herbal Help? - WebMD, 1/25/06
• Placebo-Controlled Trial Shows Which IBS Patients Respond to Probiotic Treatment - Doctor's Guide, 11/3/05
• Good Gut 'Bugs' Help Irritable Bowel Syndrome - WebMD, 10/31/05
• Jury still out on probiotics for IBS - Nutra USA, 10/31/05
• Melatonin May Reduce the Pain of Irritable Bowel Syndrome - Medscape, 10/14/05 - "Use of 3 mg of melatonin once daily for two weeks in IBS patients is associated with improvement in bowel pain and rectal distension thresholds for urgency and pain but not with a change in stool frequency, type, or quality of life"
• Exercise Cuts Irritable Bowel, Other Gut Woes - WebMD, 10/3/05
• Hypnotherapy An Effective Treatment For Irritable Bowel Syndrome - Science Daily, 9/28/05
• Probiotic Mixture Alleviates Symptoms in IBS Patients - Medscape, 9/2/05
• Probiotic bacteria helps irritable bowel syndrome - Nutra USA, 3/31/05
• Hypnotherapy for Irritable Bowel Syndrome - Clinical Psychiatry News, 3/05
• Melatonin Effective in Relieving Pain But Not Sleep Disturbance Related to Irritable Bowel Syndrome - Doctor's Guide, 9/30/04
• Hypnosis May Be Useful IBS Treatment - WebMD, 10/21/03
• Many Patients Have Dual Gastric Woes - WebMD, 10/14/03
• Fat, Fructose May Worsen Gastric Upset - WebMD, 10/13/03
• Probiotic VSL#3 Could Relieve Some Irritable Bowel Abdominal Bloating - Doctor's Guide, 4/1/03
• Peppermint Oil for Irritable Bowel Syndrome - Clinical Psychiatry News, 4/03
• Low Vitamin B6 Increases Thrombosis Risk In Inflammatory Bowel Disease - Doctor's Guide, 1/29/03
• High-Fiber Diet, Paroxetine Provide a One-Two Punch for Treatment of IBS - Clinical Psychiatry News, 12/02
• Colonic Fermentation in Irritable Bowel Not Affected By Lactobacillus Plantarum - Doctor's Guide, 12/17/02
• Probiotic LP299V Could Help Patients With Irritable Bowel - Doctor's Guide, 10/31/01 - "The probiotic Lactobacillus plantarum 299V (LP299V) appears to have a beneficial effect on patients with irritable bowel syndrome (IBS) ... All patients treated with LP299V reported resolution of their abdominal pain as compared to 11 patients from the placebo group"
• Hypnosis for Irritable Bowel - WebMD, 8/23/01
• Artichoke Leaf Extract May Provide Irritable Bowel Syndrome Relief - Doctor's Guide, 3/22/01 - "Investigators report that the IBS patients had significant reductions in the severity of their IBS symptoms. They also note that both patients and their doctors gave favourable evaluation of the overall effectiveness of the extract ... Furthermore, 96 percent of patients rated artichoke leaf extract as better than or equal to previous therapies administered for their symptoms ... Patients were found to tolerate the extract well"
• Lactobacillus Plantarum 299v Reduces Irritable Bowel Bloating -  Doctor's Guide, 3/12/01 - "Animal research has shown that it decreases translocation and improves mucosal and liver status. It also improves the immunological status of mucosa and reduces mucosal inflammation ... "Should probiotics be administered through foods," the researchers point out, "the probiotic organism must remain vigorous in the food until consumption, and the food must remain palatable.""
• Peppermint Oil Soothes Irritable Bowel Syndrome in Kids - WebMD, 2/13/01
• Behavioral Therapy Can Help Ease Irritable Bowel Syndrome - WebMD, 5/9/00
• Don't Let Vitamin D Level Dip If You Have Bowel Disease - WebMD, 4/18/00
• Arrowroot as a treatment for diarrhoea in irritable bowel syndrome patients: a pilot study - Arq Gastroenterol. 2000 Jan-Mar;37(1):20-4

Other News:

• Irritable bowel syndrome: Common gastrointestinal disorder linked to bacterial overgrowth, food poisoning - Science Daily, 5/11/11
• Antibiotic treatment effective in treating irritable bowel syndrome - Science Daily, 1/5/11
• Proof that a gut-wrenching complaint -- irritable bowel syndrome -- is not in your head - Science Daily, 8/19/10
• Cognitive behavior therapy may rapidly relieve severe irritable bowel syndrome (IBS) symptoms - Science Daily, 4/27/10
• IBS Pain Bad, Stigma Worse - WebMD, 8/20/09
• New IBS Guidelines Offer Treatment Ideas - WebMD, 12/19/08
• Soluble Fiber, Antispasmodics And Peppermint Oil Should Be Used To Treat Irritable Bowel Syndrome, Study Suggests - Science daily, 11/24/08
• New Guidelines for Treatment of Irritable Bowel Syndrome in Adults - Medscape, 5/14/08
• Amitriptyline May Alleviate Irritable Bowel Symptoms in Teens - Medscape, 5/9/08
• Breath Test Can Discriminate Between A Bacterial Overgrowth And IBS - Science Daily, 12/19/07
• Pain in IBS Linked to Psychological Factors - Physician's Weekly, 11/26/07
• Watch for Panic, Mood Disorders in IBS Patients - Clinical Psychiatry News, 11/07
• Novel Treatments May Help Alleviate Constipation, Irritable Bowel Syndrome In Women - Science Daily, 5/22/07
• Effectiveness Of Serotonin And Nerve Stimulants On Irritable Bowel Syndromes Evaluated - Science Daily, 5/22/07
• New Guidelines for Treatment of Irritable Bowel Syndrome in Adults - Medscape, 5/11/07
• Targeted Antibiotics Lead to Prolonged Improvement in IBS Symptoms - Doctor's Guide, 10/19/06
• Antibiotic May Aid Irritable Bowel - WebMD, 10/16/06
• Irritable Bowel, Pain Syndromes Linked - WebMD, 9/28/06
• Citalopram Improves Symptoms of Irritable Bowel Syndrome - Medscape, 7/24/06
• New Study Demonstrates that Amitizia (Lubiprostone) May Help Improve Symptoms of Irritable Bowel Syndrome with Constipation - Doctor's Guide, 5/30/06
• IBS Study Shows that Targeted Antibiotics Lead to Long-Lasting Improvement in Symptoms - Doctor's Guide, 11/9/05
• Rifaximin Helps in the Treatment of Irritable Bowel Syndrome - Doctor's Guide, 11/2/05
• Irritable Bowel Syndrome: Many False Fears - WebMD, 10/31/05
• Modest Efficacy Seen With Tegaserod for Treatment of Irritable Bowel Syndrome or Chronic Constipation: Presented at WCOG - Doctor's Guide, 9/19/05
• New Remedies for a Frustrating Illness. But Do They Work? - NY Times, 12/7/04
• Tegaserod Maleate Improves Productivity in Working Women With Irritable Bowel Syndrome - Doctor's Guide, 11/5/04
• New Drug Therapy May Improve Irritable Bowel Syndrome With Diarrhea - Doctor's Guide, 11/3/04
• Cilansetron Appears to Improve Health Related Quality of Life in Patients with Irritable Bowel Syndrome with Diarrhoea Predominance - Doctor's Guide, 11/2/04
• New IBS Drug May Help Stop 'Silent Suffering' - WebMD, 11/1/04
• Irritable Bowel Syndrome - Physician's Weekly, 10/11/04
• Paroxetine Effective for Irritable Bowel Syndrome - Clinical Psychiatry News, 10/04
• Stress Therapy Can Help Irritable Bowel - WebMD, 9/13/04
• Many Factors Influence Quality of Life for Patients with Irritable Bowel Syndrome - Doctor's Guide, 9/13/04
• Bacteria May Be The Cause Of Irritable Bowel Syndrome - Science Daily, 9/3/04
• Cilansetron Offers Significant Symptom Relief in Patients with Irritable Bowel Syndrome with Diarrhoea Predominance - Doctor's Guide, 5/26/04
• Anti-Depressant Drug, Paroxetine, Improves Symptoms Of Irritable Bowel Syndrome - Doctor's Guide, 5/7/04
• Treatment Options for Patients With IBS With Constipation? - Medscape, 4/8/04
• Lotronex (Alosetron HCl) 0.5mg Tablets Available in US - Doctor's Guide, 3/10/04
• Irritable Bowel Syndrome Runs in Family - WebMD, 12/18/03
• Study Suggests Familial Aggregation of IBS - Medscape, 12/17/03
• Tegaserod Rapidly Effective in Patients With Constipation-Predominant Irritable Bowel Syndrome - Doctor's Guide, 11/4/03
• Renzapride Improves Symptoms in Constipation-Predominant Irritable Bowel Syndrome - Doctor's Guide, 11/4/03
• Combo Treatment Best for IBS - WebMD, 11/3/03
• Travelers' Diarrhoea Can Trigger Irritable Bowel - Doctor's Guide, 10/22/03
• Risk of Low Bone Mineral Density Higher in Inflammatory Bowel Disease - Doctor's Guide, 10/21/03
• Advances in IBS and Other Functional GI Disorders: A Newsmaker Interview With Eamonn Quigley, MD - Medscape, 10/20/03
• Fructose Linked to Irritable Bowel Symptoms - Doctor's Guide, 10/17/03
• Many Patients with Irritable Bowel Also Suffer from Dyspepsia - Doctor's Guide, 10/17/03
• After Menopause, Women Have Same Severity of Irritable Bowel Syndrome As Men - Doctor's Guide, 10/15/03
• Infectious Gastroenteritis Linked to Irritable Bowel Syndrome - Medscape, 9/25/03
• Anxiety May Hurt Sleep Quality in Women With IBS - Clinical Psychiatry News, 9/03
• Study Links Submissive Interpersonal Style With More Severe IBS Symptoms - Clinical Psychiatry News, 9/03
• Patients with Irritable Bowel Syndrome and Constipation Unhappy with Conventional Treatments Because of Side Effects and Lack of Efficacy - Doctor's Guide, 6/9/03
• Tegaserod Helpful in Irritable Bowel Syndrome - Medscape, 5/29/03
• Subtherapeutic Doses of Antidepressants Can Control GI Symptoms - Medscape, 5/21/03
• Pattern-Specific Brain Activation and Personalities Seen in IBS - Medscape, 5/21/03
• IBS: Under-Diagnosed and Under-Treated - Physician's Weekly, 5/19/03
• Excess Body Weight and Speed of Colon Transit Linked to Idiopathic Bile Acid Malabsorption - Doctor's Guide, 5/19/03
• No Large Association Between Traveller's Diarrhoea, Risk Of Irritable Bowel Disease - Doctor's Guide, 3/31/03
• Peripheral Inflammatory Response Enhanced In Post-Gastroenteritis Irritable Bowel Syndrome - Doctor's Guide, 3/21/03
• Irritable Bowel Syndrome:  Life-threatening for none, Life Altering for many - Physician's Weekly, 3/17/03
• Irritable Bowel Syndrome More Frequent In Bacterial Gastroenteritis Patients - Doctor's Guide, 3/10/03
• Alosetron Has Positive Impact On Irritable Bowel Symptoms, Pain And Discomfort - Doctor's Guide, 3/4/03
• Antibiotic Improves Irritable Bowel Syndrome - WebMD, 2/27/03
• Normalising Abnormal Lactulose Breath Tests With Neomycin Reduces Irritable Bowel Symptoms - Doctor's Guide, 2/26/03
• Neomycin Improves Lactulose Breath Test in IBS - Medscape, 2/26/03
• One-Quarter Of Irritable Bowel Syndrome Patients Fit Alternating Bowel Habits Subtype - Doctor's Guide, 2/7/03
• Irritable Bowel Symptomatology Scoring Measures Scored - Doctor's Guide, 2/5/03
• Peptide, Neuropeptide Levels Differ among Patients with Irritable Bowel Syndrome - Doctor's Guide, 1/30/03
• Altered Visceral Perception Modulation Confirmed In Irritable Bowel Patients - Doctor's Guide, 1/29/03
• Rome I May Not Be Sensitive Enough To Detect All Irritable Bowel Patients - Doctor's Guide, 1/20/03
• Ending Bacterial Overgrowth Results in Better Motility in Some Irritable Bowel Patients - Doctor's Guide, 1/17/03
• Irritable Bowel Patients Most Often Self-Classify Symptoms As Discomfort, Not Pain - Doctor's Guide, 1/17/03
• Some Irritable Bowel Patients Genetically Predisposed To Produce Less Interleukin-10 - Doctor's Guide, 1/13/03
• Women With Diarrhoea-Predominant Irritable Bowel Satisfied With Alosetron Therapy - Doctor's Guide, 1/7/03
• Otilonium Bromide Confirmed As More Effective Than Placebo For Irritable Bowel Pain - Doctor's Guide, 12/23/02
• Two Surveys Stress High Costs of IBS - Clinical Psychiatry News, 12/02
• High-Fiber Diet, Paroxetine Provide a One-Two Punch for Treatment of IBS - Clinical Psychiatry News, 12/02
• Guidelines Target Irritable Bowel Syndrome - Clinical Psychiatry News, 12/02
• Gender Differences Reported In Vitality, Mental Health Among Irritable Bowel Patients - Doctor's Guide, 12/11/02
• Irritable Bowel Pathogenesis Involves Myenteric Plexus Neuronal Degeneration - Doctor's Guide, 12/10/02
• Osteoporosis Risks Often Overlooked Among Irritable Bowel Patients - Doctor's Guide, 12/5/02
• Irritable Bowel Syndrome Benign Despite Patient Concerns - Doctor's Guide, 12/4/02
• Lactose Intolerance Unlikely in Aetiology of Post-Infectious Irritable Bowel - Doctor's Guide, 12/3/02
• Irritable Bowel Syndrome Affects Large Number of Patients with Symptomatic Giardiasis - Doctor's Guide, 12/2/02
• Enhanced Central Nervous System Reactivity Reported in Irritable Bowel - Doctor's Guide, 11/29/02
• No Evidence for Standardised Testing in Patients Meeting Symptom-Based Irritable Bowel Criteria - Doctor's Guide, 11/26/02
• Rome I Could Be More Sensitive Than Rome II in Irritable Bowel Diagnosis - Doctor's Guide, 11/25/02
• Delayed Gastric Emptying Associated with Post-Prandial Irritable Bowel Fullness - Doctor's Guide, 11/21/02
• Lotronex (Alosetron Hydrochloride) Tablets Now Available For Women With Severe Diarrhea-Predominant Irritable Bowel Syndrome - Doctor's Guide, 11/20/02
• ACG Report Finds Drugs Effective in Irritable Bowel Syndrome - Doctor's Guide, 10/24/02
• New Study Shows Zelmac (Tegaserod) Effective and Safe for People with Non-Diarrhea Irritable Bowel Syndrome - Doctor's Guide, 10/22/02
• Inflammatory Bowel Disease Associated with Increased Risk of Fractures - Doctor's Guide, 9/23/02
• Naloxone Improves Pain Management, Symptom Control In Irritable Bowel Syndrome - Doctor's Guide, 9/2/02
• FDA Approves Zelnorm (Tegaserod Maleate), A Novel Treatment For Irritable Bowel Syndrome In Women With Constipation - Doctor's Guide, 7/24/02
• New Drug [Zelnorm] Approved to Treat IBS - WebMD, 7/24/02
• Rectal Characteristics Differ In Irritable Bowel Subtypes - Doctor's Guide, 6/25/02
• Lotronex (Alosetron) Tablets To Be Re-Introduced For Women With Severe Diarrhea-Predominant Irritable Bowel Syndrome - Doctor's Guide, 6/7/02
• Return of the Controversial Bowel Drug - WebMD, 6/7/02
• Meta-Analysis Shows Tegaserod Effective, Safe in Treatment of IBS - Doctor's Guide, 5/23/02
• Irritable Bowel Linked to Bacteria - WebMD, 5/22/02
• Higher Prevalence Of Irritable Bowel Syndrome In Patients With Gastroesophogeal Reflux Disease - Doctor's Guide, 4/11/02
• Irritable Bowel Syndrome Worse During Periods - WebMD, 3/14/02
• FDA Seeks Comments on IBS Drug [Lotronex] - WebMD, 1/25/03
• Tegaserod Benefits Some Women with Irritable Bowel - Doctor's Guide, 12/27/01
• Researchers Study Bowel Disorder - Intelihealth, 11/17/01
• Some Pain Relief Drugs Could Alleviate Irritable Bowel Syndrome - Doctor's Guide, 11/14/01
• Irritable Bowel Syndrome Patients Should Be Checked For Celiac Disease - Doctor's Guide, 11/6/01
• Zelnorm (Tegaserod) Safe, Effective for Multiple Symptoms of Irritable Bowel Syndrome - Doctor's Guide, 11/1/01
• Colas, Juices May Be Common Culprits in Intestinal Distress - WebMD, 10/22/01
• Dexloxiglumide Shows Results in Constipation-Predominant Irritable Bowel Syndrome - Doctor's Guide, 10/18/01
• Alosetron Controls Urgency in Irritable Bowel Women - Doctor's Guide, 10/10/01
• Electrogastrography Helps Distinguish Irritable Bowel From Dyspepsia - Doctor's Guide, 10/4/01
• Irritable Bowel Pain, Constipation Relief Sustained with Tegaserod - Doctor's Guide, 10/4/01
• FDA rejects Novartis IBS drug - CNN, 6/18/01
• New hope for those with irritable bowel syndrome - CNN, 5/24/01 - "The drug, called Zelnorm, improves a number of symptoms and is safe"
• Real Help for Irritable Bowel Syndrome - WebMD, 5/23/01 - "Zelnorm "stimulates motility or movement of the digestive tract, stimulates intestinal secretions, and inhibits visceral sensitivity or the perception of pain ... works by mimicking the effects of the naturally occurring chemical called serotonin"
• Patients Demand Return of Irritable Bowel Drug - WebMD, 4/20/01
• Acupuncture Not Significantly Beneficial In IBS Symptoms - Doctor's Guide, 3/13/00
• Breath Test Helps Sniff Out Irritable Bowel Syndrome - WebMD, 12/13/00
• IBS Drug Withdrawn After Less Than a Year on the Market - WebMD, 11/28/00
• More Upsetting News About Irritable Bowel Treatment - WebMD, 10/31/00
• Death Reports Prompt Another FDA Probe Of Bowel Drug - Intelihealth, 10/31/00
• Alosetron Reduces Lost Work Time in Women with Irritable Bowel Syndrome - Doctor's Guide, 10/16/00
• FDA Warns Women About Side Effects From Irritable Bowel Treatment - Intelihealth, 8/25/00
• FDA Meets On Lotronex Bowel Drug - Intelihealth, 6/28/00
• FDA Committee Recommends Zelmac (Tegaserod) For Women With Irritable Bowel Syndrome - Doctor's Guide, 6/27/00
• Venlafaxine Extended Release Effective And Safe For Generalized Anxiety Disorder - Doctor's Guide, 6/20/00
• Sleep Disruptions Common In Irritable Bowel Syndrome - Doctor's Guide, 5/25/00
• Zelmac (Tegaserod) Relieves Multiple Symptoms Of Irritable Bowel Syndrome - Doctor's Guide, 5/24/00
• High Prevalence of Irritable Bowel Syndrome Linked To Anxiety Disorder In Men - Doctor's Guide, 5/23/00
• Patient-reported Questionnaire Reliable For Irritable Bowel Syndrome - Doctor's Guide, 5/23/00
• Acupuncture Not Significantly Beneficial In IBS Symptoms - Doctor's Guide, 3/13/00
• FDA Approves Lotronex (alosetron) For Irritable Bowel Syndrome In Women - Doctor's Guide, 2/9/00
• Zelmac Shows Promise In Irritable Bowel Syndrome - Doctor's Guide, 10/25/99
• Alosetron Yields Relief In Non-Constipated Women With IBS - Doctor's Guide, 10/21/99
• Tegaserod Reduces Discomfort, Improves Bowel Function - Doctor's Guide, 10/20/99
• New Treatments Show Promise For IBS And Chronic Constipation - Doctor's Guide, 10/18/99
• Research Links Irritable Bowel And Mitral Valve Prolapse - Doctor's Guide, 9/7/99
• Lotronex Benefits Women With Irritable Bowel Syndrome - Doctor's Guide, 5/25/99
• Lotronex Appears Promising As Treatment For IBS - Doctor's Guide, 5/18/99
• Male Sex Hormones May Protect Against Irritable Bowel Syndrome - Doctor's Guide, 5/18/99 (see second article)
• Fermentation May Be At Root Of Irritable Bowel Syndrome - Doctor's Guide, 10/9/98
• What Really Causes Irritable Bowel Syndrome? - Doctor's Guide, 1/27/98
• Cause Of IBS Still A Mystery Leading Some To Doubt Its Existence - Doctor's Guide, 12/5/97
• Millions Suffer From Irritable Bowel Syndrome, But Most Never Heard Of It - Doctor's Guide, 4/29/97