|
|
Home >
Anti-aging Research > Yoghurt
Yogurt
My yogurt recipe:
I use the
Yogourmet Electric Yogurt Maker.
I worried about the BPA in the plastic container I use the
glass jars sold at Amazon. I mix one
and three quarters cups of Peak whole milk powder and one
and three quarters cups of Carnation non-fat dry milk with water in a blender.
The cheaper brands of whole milk powder don't work for some reason, use the
Peak brand. I pour that in the yogurt
jar and top it off with water. Then I put that in the microwave for four
minutes to bring it to about 110 degrees. Then
I add one container of vanilla flavored Activia
for the culture. Don't use the Activia that says "70 calories". It
doesn't come out right for some reason. I put that in the Yogourment for
10 hours. Then I pour that into the
yogurt strainer for another 20 hours in the refrigerator. I flavor it with
Smucker's Orchard's Finest Strawberry.
The Pyrex is the perfect size to store the Greek
yogurt.
News & Research:
-
A daily
dose of yogurt could be the go-to food to manage high blood pressure -
Science Daily, 12/7/21 - "Dairy foods, especially
yoghurt, may be capable of reducing blood pressure ... This is because dairy
foods contain a range of micronutrients, including calcium, magnesium and
potassium, all of which are involved in the regulation of blood pressure ...
Yoghurt is especially interesting because it also contains bacteria that promote
the release of proteins which lowers blood pressure ... This study showed for
people with elevated blood pressure, even small amounts of yoghurt were
associated with lower blood pressure ... And for those who consumed yoghurt
regularly, the results were even stronger, with blood pressure readings nearly
seven points lower than those who did not consume yoghurt" - Note:
Go with the recipe on this page or go with the Noosa brand at the grocery store.
-
The association between
daily yogurt consumption and serum lipid profiles in the general adult
population: the TCLSIH cohort study - Int J Food Sci Nutr 2021 Nov 9 -
"In the final multivariate model, daily yogurt
consumption was negatively associated with triglyceride (TG) (p for trend
<0.001) and positively associated with high density lipoprotein cholesterol
(HDL-C) (p for trend = 0.02). There were no significant differences (p for trend
>0.05) between daily yogurt consumption and total cholesterol (TC) or low
density lipoprotein cholesterol (LDL-C). Results suggested that higher daily
yogurt consumption was negatively correlated with TG and positively correlated
with HDL-C in the general Chinese population"
-
Eating
yogurt may reduce cardiovascular disease risk - Science Daily, 2/15/18 -
"Higher intakes of yogurt were associated with a 30
percent reduction in risk of myocardial infarction among the Nurses' Health
Study women and a 19 percent reduction in the Health Professionals Follow-Up
Study me ... In both groups, participants consuming more than two servings a
week of yogurt had an approximately 20 percent lower risks of major coronary
heart disease or stroke during the follow-up period"
-
Homemade Yogurt Resolves
Irritable Bowel Symptoms - Medscape, 12/7/17 - "We
had 189 patients in the study, and 169 had remission within 6 months ... And
some of the participants had lived with symptoms of irritable bowel syndrome for
9 or 10 years ... Complete remission — defined as the relief of pre-existing
irritable bowel syndrome symptoms and one or two normal bowel movements daily —
was achieved by 89% of the study participants" - Note: I've had
yogurt made the way indicated in this article many times made by different
people. It's not palatable. Try the recipe on my
yogurt page.
-
Daily Yogurt Consumption
Leads to Better Bone Health - Medscape, 9/23/16 -
"Healthy postmenopausal women who eat at least one serving of yogurt a day have
a lower body mass index (BMI), less fat, and better bone density — at least at
some skeletal sites — than women who never consume yogurt ... Yogurt is a source
of nutrients, in particular calcium and protein, but it also contains fermented
daily products and probiotics, all of which are potentially beneficial for bone
health ... At baseline, women who consumed yogurt (over 91% of the cohort) had a
4.4% higher BMD value at the lumbar spine than women who never consumed yogurt
... Women who consumed yogurt were also 6.4% leaner than those who never ate it,
again independent of total energy intake and physical activity ... the
prevalence of low trauma fractures trended toward a lower rate, at 19% among
yogurt consumers vs 29% for nonconsumers"
-
Greek? Nonfat? Fruit-flavored? A dietitian dishes on yogurt - NYT, 5/3/16 -
"A key recommendation in the latest Dietary Guidelines
for Americans is to choose low-fat or fat-free because dairy fat is mostly
saturated, the type linked with increased cholesterol and risk of heart disease.
Also, full-fat dairy has more calories than nonfat, so it seems logical that
forgoing the fat would be a better choice for keeping weight in check ... But
this view has been challenged recently with a few well-publicized studies that
surprisingly link the fat in dairy with a lower risk of obesity, heart disease
and diabetes. Researchers surmise that full-fat dairy might offer some
as-yet-unknown health benefit. It also might help with weight management because
the fat in it makes it more satisfying, helping keep your appetite in check ...
It’s worth repeating that there’s no need to worry about the sugars that are
inherent in dairy products. They’re naturally “packaged” with so many important
nutrients that it would be misguided to avoid them. It’s the sweeteners added to
these foods that are best kept to a minimum"
-
Dairy Consumption and Risk
of Frailty in Older Adults: A Prospective Cohort Study - Medscape, 10/29/15
- "Participants consuming seven or more servings per
week of low-fat milk and yogurt had lower incidence of frailty (OR = 0.52; 95%
confidence interval (CI) = 0.29–0.90; P for trend = .03) than those consuming
less than one serving per week. Specifically, consumers of seven or more
servings per week of low-fat milk and yogurt had less risk of slow walking speed
(OR = 0.64, 95% CI = 0.44–0.92, P trend = .01) and of weight loss (OR = 0.54,
95% CI = 0.33–0.87, P trend = .02). Consuming seven or more servings per week of
whole milk or yogurt (OR = 1.53, 95% CI = 0.90–2.60, P trend = .10) or of cheese
(OR = 0.91, 95% CI = 0.52–1.61; P trend = .61) was not associated with incident
frailty"
-
Milk and
dairy consumption correlates with cerebral cortical as well as cerebral white
matter volume in healthy young adults - Int J Food Sci Nutr. 2015 Oct 5:1-4
- "Total cerebral cortex, total cerebral white matter,
and total cerebral parenchyma were significantly related with cottage cheese and
total protein intake from milk and dairy also when controlled for age and gender
in the multivariate model. Our results indicate that dietary habits related with
milk and dairy are proportionally associated with volumes of both cerebral
cortex and cerebral white matter"
-
Yogurt May Lower Diabetes Risk - NYTimes.com, 11/24/14 -
"Researchers followed almost 200,000 men and women ages
25 to 75 for as long as 30 years, tracking their health with periodic interviews
and their diets with detailed food questionnaires ... total dairy consumption,
either high-fat or low-fat, was not associated with the risk for Type 2 diabetes
... But yogurt was different. Compared to eating the average amount of 4 ounces
a day, eating 12 ounces a day was associated with an 18 percent reduction in the
risk for Type 2 diabetes"
-
Best and Worst Foods for Bloating - ABC News, 5/7/14 -
"Best: Yogurt with probiotics ... Get some of those good
bacteria into your gut! Called probiotics, they help regulate digestion and
champion the overall health of your digestive tract. Sure, you can take
probiotic supplements, but you may as well get a breakfast out of it"
-
Top 4 Foods for Thicker, Shinier Hair - ABC News, 4/29/14 -
"Yogurt ... These good bacteria help balance the
community of microorganisms that live in our intestines. And a recent study by
MIT researchers suggests that probiotics help produce that “healthy glow” we all
want, by making skin more radiant and hair more shiny, thick, and lustrous"
-
Top 3 Foods for a Longer Life - ABC News, 4/21/14 -
"resveratrol increases the activity of specific genes called sirtuins that
protect against diseases of aging by revving up the mitochondria, the little
batteries inside our cells ... mice fed the bacterial strain Bifidobacterium
animalis lactis lived longer and were healthier than mice that did not receive
the probiotic ... people who consume 650 mg a day of polyphenols live longer
than those who get less then that" - See
resveratrol products at Amazon.com
and
Garden of Life, Radical Fruits Antioxidant Complex at Amazon.com.
-
Could Low-Fat Yogurt Help Ward Off Diabetes? - WebMD, 2/5/14 -
"Emerging research suggests that gut microbes play
important roles in the development of type 2 diabetes, inflammation and other
diseases ... Forouhi and colleagues collected data on 4,255 men and women who
were part of a larger British study. This group included 753 people who
developed type 2 diabetes over 11 years of follow-up and 3,502 randomly selected
people for comparison ... the amount of high-fat dairy or total low-fat dairy
was not linked to the risk of developing diabetes -- once factors like healthy
lifestyles, education, obesity, other eating habits and total calorie intake
were taken into account ... Milk and cheese consumption was also not associated
with the risk of developing diabetes ... what was significant was the amount of
low-fat fermented dairy products, such as yogurt, fromage frais (a fresh,
low-fat curd cheese similar to cottage cheese), and low-fat cottage cheese
participants ate ... For those who ate the most of these foods, the risk of
developing diabetes shrank 24 percent, compared with those who didn't eat any
... When the investigators looked specifically at yogurt, the risk of developing
diabetes was reduced by 28 percent ... The lowered risk was seen among people
who ate about 4.5 standard 125-gram cups (about 4.4 ounces each) of yogurt a
week"
-
Probiotics a Potential
Treatment for Mental Illness - Medscape, 11/19/13 -
"Another study of 124 volunteers (mean age, 61.8 years) showed that those who
consumed probiotic-containing yogurt for 3 weeks had significantly improved mood
compared with those who received placebo" - See
probiotic products at Amazon.com.
-
Is Dairy
Intake Associated to Breast Cancer? A Case Control Study of Iranian Women -
Nutr Cancer. 2013 Sep 25 - "100 cases and 175 controls
... Dietary data were assessed using a validated food frequency questionnaire
... We observed that higher consumption of total dairy intake was accompanied
with reduced breast cancer risk [odds ratio (OR) = 0.14, 95% CI = 0.04-0.38]. A
similar inverse association was also observed for higher intakes of low-fat and
fermented dairy products (P for trend <0.05). Lower intake of high-fat dairy was
associated with reduced odds of breast cancer, and no significant association
was found between nonfermented dairy and breast cancer risk. Our study
demonstrates the protective effects of high intakes of total dairy, low-fat and
fermented dairy, as well as low intakes of high-fat dairy products against
breast cancer risk and shows no association with nonfermented dairy" -
Note: Did I read that right, '0.14' or an 86% reduction in risk? See my yogurt
recipe at the top of this page.
-
Changing
Gut Bacteria Through Diet Affects Brain Function - Science Daily, 5/28/13 -
"Time and time again, we hear from patients that they
never felt depressed or anxious until they started experiencing problems with
their gut ... Researchers divided the women into three groups: one group ate a
specific yogurt containing a mix of several probiotics -- bacteria thought to
have a positive effect on the intestines -- twice a day for four weeks; another
group consumed a dairy product that looked and tasted like the yogurt but
contained no probiotics; and a third group ate no product at all ... compared
with the women who didn't consume the probiotic yogurt, those who did showed a
decrease in activity in both the insula -- which processes and integrates
internal body sensations, like those form the gut -- and the somatosensory
cortex during the emotional reactivity task ... Further, in response to the
task, these women had a decrease in the engagement of a widespread network in
the brain that includes emotion-, cognition- and sensory-related areas. The
women in the other two groups showed a stable or increased activity in this
network" - See
probiotic products at Amazon.com
or my yogurt recipe above.
-
Stressful day ahead? Grab a yogurt for breakfast - TODAY Health, 10/12/12 -
"Researchers from the University of Cork fed mice a diet
full of Lactobacillus rhamnosus (JB-1), bacteria that colonize the gut that
provide healthy digestion and prevent diarrhea, and found that the mice
exhibited fewer signs of depression and anxiety and expressed less
corticosterone, a stress hormone. A regular diet of probiotics changed the brain
chemistry in the mice -- probiotics modified how the mice expressed receptors
for the neurotransmitter GABA, suggesting that probiotics change neurochemistry"
-
Sesame & Rice Bran Oil, Yogurt Help Blood Pressure - WebMD, 9/19/12 -
"The first study showed a sesame and rice bran oil blend
reduced blood pressure almost as well as a commonly used medication. And the
second study found that people who routinely eat yogurt are less likely to
develop high blood pressure ... In the yogurt study, about 2,000 adults without
high blood pressure were followed for 14 years. The researchers found that
participants were 31% less likely to develop high blood pressure if more than 2%
of their daily calories came from yogurt" - See
sesame seed oil at Amazon.com and
rice bran oil at Amazon.com.
-
Yogurt Makes Mice Slimmer, Sexier - ABC News, 5/7/12 -
"Not only does yogurt make mice slimmer; it also makes
them sexier ... Maybe probiotics in the yogurt have something to do with the
effects on weight ... It turns out their testicles were 5 percent bigger than
those of their non-yogurt eating counterparts, and 15 percent bigger than those
of mice on a diet designed to mimic “junk food” in humans. And in this case,
bigger was better ... And let’s not forget the ladies. Female mice that ate
yogurt were even shinier than the males, and tended to be better moms to their
larger litters"
-
Greek yogurt on a marathon-like growth spurt - USATODAY.com, 1/23/12 -
"Greek yogurt is made a bit differently than the
thinner, more watery product that dominated U.S. supermarket shelves for
decades. The whey is strained off, leaving a creamier yogurt high in protein and
low in fat"
-
Probiotic intake linked to fewer birth complications - Nutra USA, 9/13/11 -
"The Norwegian researchers analyzed data from 33,399
women participating in the Norwegian Mother and Child Cohort Study ... The
intake of lactobacilli-containing milk-based products was determined using a
food frequency questionnaire, while pre-eclampsia was determined using the
Norwegian Medical Birth Registry ... the daily intake of at least 140 mL of
probiotic milk products was associated with a 20% reduced risk of pre-eclampsia
... The effects were more pronounced for severe pre-eclampsia, with daily and
weekly intakes of probiotic products associated with a 39% and 25%,
respectively" - [Abstract]
-
Foods
rich in protein, dairy products help dieters preserve muscle and lose belly fat
- Science Daily, 8/29/11 - "a higher-protein,
lower-carbohydrate energy-restricted diet has a major positive impact on body
composition, trimming belly fat and increasing lean muscle, particularly when
the proteins come from dairy products ... compared three groups of overweight
and obese, but otherwise healthy, premenopausal women. Each consumed either low,
medium or high amounts of dairy foods coupled with higher or lower amounts of
protein and carbohydrates ... there were identical total weight losses among the
groups, but the higher-protein, high-dairy group experienced greater whole-body
fat and abdomen fat losses, greater lean mass gains and greater increases in
strength ... One hundred per cent of the weight lost in the higher-protein,
high-dairy group was fat. And the participants gained muscle mass, which is a
major change in body composition ... the lower-protein, low-dairy group lost
about a pound and half of muscle whereas the lower-protein, medium dairy group
lost almost no muscle. In marked contrast, the higher-protein, high-dairy group
actually gained a pound and half of muscle, representing a three-pound
difference between the low- and high-dairy groups ... On top of the muscle mass
differences, the higher-protein, high-dairy group lost twice as much belly fat
than the lower-protein, low-dairy group ... These women also got fitter and
stronger"
-
Potatoes bad, nuts good for staying slim, Harvard study finds - The
Washington Post, 6/22/11 - "But is a serving of boiled
potatoes really much worse than a helping of nuts? Is some white bread as bad as
a candy bar? Could yogurt be a key to staying slim? ... The answer to all those
questions is yes, according to the provocative revelations produced by a big
Harvard project that for the first time details how much weight individual foods
make people put on or keep off ... Although calories remain crucial, some foods
clearly cause people to put on more weight than others, perhaps because of their
chemical makeup and how our bodies process them ... starches and refined
carbohydrates such as potatoes cause blood sugar and insulin to surge, which
makes people feel less satisfied and eat more as a result ... Researchers will
surely scramble to try to explain why
yogurt appears so helpful. It may be because of
subtle shifts of microbes in the digestive tract, or perhaps because people who
eat more yogurt also tend to do other healthy things"
-
You don’t want fries with that - The Washington Post, 6/22/11 - It's the
full graphic from the above article. A must see.
-
Study: Some foods help shed pounds, others help pack them on - The
Washington Post, 6/22/11 - It's a nine slide slideshow on the above
article. It's a little confusing. You need to select "Autoplay" plus read
what is says on the right.
-
To Keep Off Pounds: Pass The Nuts, Hold The Chips - NPR, 6/23/11 - NPR
article on the same study.
-
Harvard Study Measures Four-Year Weight Gain Associated With One More Daily
Serving of Potato Chips, French Fries - WSJ.com, 6/23/11 -
"An additional daily serving of certain foods was
associated with weight loss over a four year period ... Yogurt -0.82 pounds
... Nuts -0.57 pounds ... Fruits -0.49 pounds ... Whole grains -0.37 pounds
... Vegetables -0.22 pounds ... Source: NEJM"
- See my yogurt recipe at the top of my Yogurt
Page. I practically live on that stuff because I have trouble
swallowing after my throat cancer surgery
six and a half years ago. See
New
way to identify patients at risk of dysphagia after head and neck cancer
treatment - Science Daily, 2/25/11 - "Dysphagia
may be acute (starting in direct association with treatment) or late
(starting months to years after treatment). Risk factors for developing
severe acute dysphagia were large tumours, spreading of cancer cells to the
lymph nodes"
-
Yogurt may boost immune function in at-risk populations - Nutra USA, 6/21/11
-
Comfort
food: Protein from probiotic bacteria may alleviate inflammatory bowel disorders
- Science Daily, 5/23/11 - "A protein isolated from
beneficial bacteria found in yogurt and dairy products could offer a new, oral
therapeutic option for inflammatory bowel disorders (IBD) ... the protein
supports intestinal epithelial cell growth and function, and reduces
inflammatory responses that can cause intestinal cells to die. Importantly, the
investigators showed that oral consumption of p40 by mice in a protective
delivery system prevents and treats colitis in multiple models of the disease
... Many of the hundreds of bacterial species that live in our gut (known as the
"human microbiome") are helpful to us: they help us digest certain substances,
produce vitamins and fight off more dangerous bacteria. But miscommunication
between these bacteria and our gut lining can lead to conditions like ulcerative
colitis and Crohn's disease"
-
Component in common dairy foods may cut diabetes risk, study suggests -
Science Daily, 12/20/10 - "The compound,
trans-palmitoleic acid, is a fatty acid found in milk, cheese, yogurt, and
butter ... trans-palmitoleic acid may underlie epidemiological evidence in
recent years that diets rich in dairy foods are linked to lower risk of type
2 diabetes and related metabolic abnormalities. Health experts generally
advise reducing full-fat dairy products, but trans-palmitoleic acid is found
in dairy fat ... At baseline, higher circulating levels of trans-palmitoleic
acid were associated with healthier levels of blood cholesterol,
inflammatory markers, insulin levels, and insulin sensitivity, after
adjustment for other risk factors. During follow-up, individuals with higher
circulating levels of trans-palmitoleic acid had a much lower risk of
developing diabetes, with about a 60% lower risk among participants in the
highest quintile (fifth) of trans-palmitoleic acid levels"
-
Dannon's Activia, DanActive health claims draw $21M fine - USATODAY.com,
12/15/10 - "Dannon will stop claiming that one daily
serving of Activia yogurt relieves irregularity and that DanActive helps
people avoid catching colds" - Here's the reason I used Activia to
make my own yoghurt (first bullet). This article doesn't address it. I
never did buy off on the irregularity claim but there might be some support
for colds:
-
Dannon Activia | How Activia Helps - Activia.com -
"This is where Activia, with Bifidus Regularis®,
can help! Activia is shown in several clinical studies to survive
passage through the digestive system and arrive in the gut in enough
quantities to help have a positive impact on slow intestinal transit"
-
Probiotics show potential against common cold: Study - Nutra USA 9/21/10
-
"daily consumption of Lactobacillus plantarum HEAL 9
(DSM 15312) and Lactobacillus paracasei 8700:2 (DSM 13434) reduced the
incidence of one or more episodes of the common cold from 67 percent in the
placebo group to 55 percent, according to findings published in the European
Journal of Nutrition ... Furthermore, the number of days of symptoms for the
cold was significantly reduced in people taking the probiotic supplements,
from an average of 8.6 to 6.2, compared with placebo ... the total symptom
score was reduced during the study period from a mean of 44.4 for the
control group to 33.6 for the probiotic group"
-
The Benefits
of Yogurt - WebMD, 3/7/07 - "your body needs to
have a healthy amount of ''good'' bacteria in the digestive tract ... Yogurt
May Help Prevent Osteoporosis ... Yogurt May Reduce the Risk of High Blood
Pressure ... Yogurt With Active Cultures Helps the Gut ... Yogurt With
Active Cultures May Discourage Vaginal Infections ... Yogurt May Help You
Feel Fuller"
-
Gut
bacteria could be key indicator of colon cancer risk - Science Daily,
6/24/10-
"a shift in the balance between the "good" bacteria
and the "bad" bacteria that populate our gut could be a harbinger of colon
cancer ... We think something happens to tip the balance away from the
beneficial bacteria and in favor of microbes that make toxic metabolites and
are detrimental to our health ... By pinpointing these bacterial culprits,
we can not only identify people at risk, but also suggest that they include
the good bacteria in their diet .. And what a great way to address colon
cancer -- you could know your risk and lower it by eating your yogurt every
day" - Note: Dannon claims that only their Activia brand reaches the
gut. see:
-
Activia by Dannon
- "Specialists at Dannon® selected Bifidus
Regularis™ for Activia® because it survives passage through the
digestive tract, arriving in the colon as a living culture. Once there,
it plays a beneficial role in your intestinal ecosystem"
-
15 best age-erasing superfoods - MSNBC, 5/25/10 -
"Yogurt ... Various cultures claim yogurt as their
own creation, but the 2,000-year-old food’s health benefits are not
disputed: Fermentation spawns hundreds of millions of probiotic organisms
that serve as reinforcements to the battalions of beneficial bacteria in
your body, which keep your digestive tract healthy and your immune system in
top form, and provide protection against cancer. Not all yogurts are
probiotic, though, so make sure the label says “live and active cultures.”"
-
Yogurt-like drink DanActive reduced rate of common infections in daycare
children - Science Daily, 5/19/10 - "Researchers
found a 19 percent decrease of common infections among the children who
drank the yogurt-like drink with L. casei DN-114 001 compared to those whose
drink did not have the probiotic. More specifically, those who drank
DanActive had 24 percent fewer gastrointestinal infections (such as
diarrhea, nausea, and vomiting), and 18 percent fewer upper respiratory
tract infections (such as ear infections, sinusitis and strep). However, the
reduction in infections did not result in fewer missed school days or
activities -- also a primary outcome of the study" - [Abstract]
-
New Yogurt Fights Stomach Ulcers - WebMD, 3/22/09 -
"H. pylori uses an enzyme called urease to attach to
and infect the inside of the stomach. This latest yogurt, designed to fight
stomach ulcers, contains an antibody called
IgY-urease. The yogurt is marketed as Dr. Piro in Japan and as Gut in Korea.
Researchers are hopeful that their clinical trial will pave the way for
approval in the United States ... For the trial, scientists recruited 42
people who tested positive for H. pylori. Some participants ate the yogurt
with the antibody three times a day for four weeks. Some participants ate
the same amount of regular yogurt that didn't contain the antibody. H.
pylori activity was significantly reduced in the antibody yogurt group"
-
Probiotic Yogurt May Help Eradicate H. pylori Infection - Medscape,
4/17/06 - "Four weeks of pretreatment with AB-yogurt
before quadruple therapy improves eradication rate of residual H. pylori after
failed triple therapy"
Abstracts:
-
Total dairy consumption in
relation to overweight and obesity in children and adolescents: A systematic
review and meta-analysis - Obes Rev 2021 Dec 8 -
"results showed an inverse association between total dairy consumption and
obesity prevalence (OR (95% CI): 0.66 (0.48-0.91). No significant associations
were found between milk or yogurt and obesity prevalence risk. Regarding
prospective studies, total milk consumption was positively associated with
overweight prevalence (OR (95% CI): 1.13 (1.01-1.26)) and incidence (RR (95%CI):
1.17 (1.01-1.35)) risk. Evidence from pooled analysis of cross-sectional studies
suggested an inverse association between total dairy consumption and obesity"
-
Probiotic-containing yogurt protects against microbiome changes that lead to
antibiotic-induced diarrhea - Science Daily, 9/14/21 -
"The study found that yogurt containing the probiotic
Bifidobacterium lactis BB-12 worked better than a placebo at maintaining the
community of bacteria in the colon"
-
Effect of the Lactococcus
Lactis 11/19-B1 Strain on Atopic Dermatitis in a Clinical Test and Mouse Model
- Nutrients. 2020 Mar 14 - "Some lactic acid bacteria
(LAB) are known to improve atopic dermatitis (AD) through the regulation and
stimulation of the host immune system. In this study, we found that ingestion of
yogurt containing Lactococcus lactis 11/19-B1 strain (L. lactis 11/19-B1) daily
for 8 weeks significantly improved the severity scoring of atopic dermatitis
(SCORAD) system score from 38.8 ± 14.4 to 24.2 ± 12.0 in children suffering from
AD ... AD-like skin lesions on the dorsal skin and ear were most improved by L.
lactis 11/19-B1 intake among the five LAB species. In addition, analysis of CD4+
T cell subsets in Peyer's patches (PPs) and cervical lymph nodes (CLNs)
indicated that the intake of L. lactis 11/19-B1 generally suppressed all subsets
related to inflammation, i.e., Th1, Th2 and Th17, instead of activating the
suppressive system, Treg, in the AD mouse model. Histological observations
showed ingestion of L. lactis 11/19-B1 significantly suppressed severe
inflammatory findings, such as inflammatory cell filtration, epidermal erosion
and eosinophil infiltration. These results suggest that the immunomodulatory
effects of L. lactis 11/19-B1 contribute to improvements in AD pathology"
- [Nutra
USA]
-
Effects of 12-Week Ingestion
of Yogurt Containing Lactobacillus plantarum OLL2712 on Glucose Metabolism and
Chronic Inflammation in Prediabetic Adults: A Randomized Placebo-Controlled
Trial - Nutrients. 2020 Jan 31 - "The ingestion of
Lactobacillus plantarum OLL2712 (OLL2712) cells improved glucose metabolism by
suppressing chronic inflammation in mouse models and in a preliminary clinical
study. We aimed to clarify the effect of OLL2712 on glucose metabolism and
chronic inflammation for healthy adults. Prediabetic adults (n = 130, age range:
20-64 years) were randomly assigned to either the placebo or OLL2712 groups (n =
65 each) and were administered conventional yogurt or yogurt containing more
than 5 × 109 heat-treated OLL2712 cells, respectively, daily for 12 weeks.
Reduced HbA1c levels after 12 weeks of treatment were observed in both groups
compared to those at baseline; however, the 12-week reduction of HbA1c levels
was significantly greater in the OLL2712 group than in the placebo group.
Increased chronic inflammation marker levels and insulin-resistant index
(HOMA-IR) occurred in the placebo group but not in the OLL2712 group. Fasting
blood glucose (FBG) levels did not change significantly in both groups; however,
in subgroup analyses including participants with higher FBG levels, FBG levels
were significantly reduced only in the OLL2712 group compared to baseline. These
results suggest that OLL2712 cell ingestion can reduce HbA1c levels and can
prevent the aggravation of chronic inflammation and insulin resistance" -
[Nutra
USA]
-
Yogurt Is a Low-Glycemic
Index Food - J Nutr. 2017 Jun 14 - "Because the GI
of yogurt is lower than that of most other carbohydrate foods, exchanging yogurt
for other protein and carbohydrate sources can reduce the GI and GL of the diet,
and is in line with recommended dietary patterns, which include whole grains,
fruits, vegetables, nuts, legumes, fish, vegetable oils, and yogurt"
-
Yogurt and Diabetes:
Overview of Recent Observational Studies - J Nutr. 2017 Jun 14 -
"We found that 13 prospective studies evaluated the
association between yogurt intake and type 2 diabetes, most of which showed an
inverse association between the frequency of yogurt consumption and the risk of
diabetes. In addition to the scientific evidence accumulated from individual
prospective studies, several meta-analyses have shown that yogurt consumption
has a potential role in diabetes prevention. The most recent analysis shows a
14% lower risk of type 2 diabetes when yogurt consumption was 80-125 g/d
compared with no yogurt consumption"
-
Consumption of Dairy
Yogurt Containing Lactobacillus paracasei ssp. paracasei, Bifidobacterium
animalis ssp. lactis and Heat-Treated Lactobacillus plantarum Improves Immune
Function Including Natural Killer Cell Activity - Nutrients. 2017 May
31;9(6) - "Over a twelve-week period, the test group
consumed dairy yogurt containing probiotics each day, whereas the placebo group
consumed milk. Natural killer (NK) cell activity, interleukin (IL)-12 and
immunoglobulin (Ig) G1 levels were significantly increased in the test group at
twelve weeks compared to baseline. Additionally, the test group had
significantly greater increases in serum NK cell activity and interferon (IFN)-γ
and IgG1 than placebo group" - [Nutra
USA]
-
The Potential Role of
Yogurt in Weight Management and Prevention of Type 2 Diabetes - J Am Coll
Nutr. 2016 Jun 22:1-15 - "Yogurt possesses unique
properties, including its nutritional composition; lactic acid bacteria, which
may affect gut microbiota; and food matrix, which may have a potential role in
appetite and glycemic control ... Potential mechanisms of action of yogurt
include an increase in body fat loss, decrease in food intake and increase in
satiety, decrease in glycemic and insulin response, altered gut hormone
response, replacement of less healthy foods, and altered gut microbiota ... The
relative energy and nutrient content and contribution of a standard portion of
yogurt to the overall diet suggest that the percentage daily intake of these
nutrients largely contributes to nutrient requirements and provides a strong
contribution to the regulation of energy metabolism"
-
Yogurt
consumption and abdominal obesity reversion in the PREDIMED study - Nutr
Metab Cardiovasc Dis. 2015 Dec 12 - "consumption of
whole-fat yogurt was associated with changes in waist circumference and higher
probability for reversion of abdominal obesity. Therefore, it seems that
whole-fat yogurt has more beneficial effects in management of abdominal obesity
in elderly population at high cardiovascular risk"
-
Dairy
Consumption Lowers Systemic Inflammation and Liver Enzymes in Typically
Low-Dairy Consumers with Clinical Characteristics of Metabolic Syndrome - J
Am Coll Nutr. 2015 Nov 23:1-7 - "This was a randomized
study in which participants consumed low-fat dairy (LFD) (10 oz 1% milk, 6 oz
nonfat yogurt, 4 oz 2% cheese) or a carbohydrate-based control (CNT) (1.5 oz
granola bar and 12 oz 100% juice) for 6 weeks ... Participants had lower
concentrations of both hepatic alanine aminotransferase (p < 0.05) and aspartate
aminotransferase (p < 0.005) after the LFD period. No significant changes in any
of the plasma inflammatory compounds were found when all data were analyzed
together. In contrast, expression of IL-1b and IL-6 were reduced by 46% and 63%,
respectively, compared to the control period ... We conclude that three dairy
servings per day improved both liver function and systemic inflammation in
subjects with MetS"
-
Longitudinal
association of dairy consumption with the changes in blood pressure and the risk
of incident hypertension: the Framingham Heart Study - Br J Nutr. 2015 Sep
23 - "incident hypertension (HTN) ... Greater intakes of total dairy foods,
total low-fat/fat-free dairy foods, low-fat/skimmed milk and yoghurt were
associated with smaller annualised increments in SBP and a lower risk of
projected HTN incidence. However, with the exception of total dairy foods and
yoghurt, these inverse associations with HTN risk were attenuated as the
follow-up time increased. For yoghurt, each additional serving was associated
with 6 (95 % CI 1, 10) % reduced risk of incident HTN. Total dairy and total
low-fat/fat-free dairy intakes were found to be inversely related to changes in
DBP. Dairy consumption, as part of a nutritious and energy-balanced diet
pattern, may benefit BP control and prevent or delay the onset of HTN"
-
Consumption
of Yogurt, Low-Fat Milk, and Other Low-Fat Dairy Products Is Associated with
Lower Risk of Metabolic Syndrome Incidence in an Elderly Mediterranean
Population - J Nutr. 2015 Aug 19 - "dietary habits
by a 137-item validated food-frequency questionnaire, and blood biochemistry
determinations ... median follow-up of 3.2 y ... the comparison of extreme
tertiles of dairy product consumption were 0.72 (0.61, 0.86) for low-fat dairy,
0.73 (0.62, 0.86) for low-fat yogurt, 0.78 (0.66, 0.92) for whole-fat yogurt,
and 0.80 (0.67, 0.95) for low-fat milk. The respective HR for cheese was 1.31"
-
Associations
between Yogurt, Dairy, Calcium, and Vitamin D Intake and Obesity among U.S.
Children Aged 8-18 Years: NHANES, 2005-2008 - Nutrients. 2015 Mar
3;7(3):1577-93 - "Yogurt intake was associated with
lower total fat and saturated fat intakes and body fat as measured by
subscapular skinfold thickness"
-
Yogurt
consumption, weight change and risk of overweight/obesity: The SUN cohort study
- Nutr Metab Cardiovasc Dis. 2014 Jun 15 - "Participants
were classified in 5 categories of yogurt consumption at baseline: 0-2, >2-<5,
5-<7, 7 and ≥7 servings/week. Outcomes were: 1) average yearly weight change
during follow-up; and 2) incidence of overweight/obesity. Linear regression
models and Cox models were used to adjust for potential confounders. After a
median follow-up of 6.6 years, 1860 incident cases of overweight/obesity were
identified. A high (>7 servings/week) consumption of total and whole-fat yogurt
was associated with lower incidence of overweight/obesity [multivariable
adjusted hazard ratios = 0.80 (95% CI: 0.68-0.94); and 0.62 (0.47-0.82)
respectively] in comparison with low consumption (0-2 servings/week). This
inverse association was stronger among participants with higher fruit
consumption"
-
Probiotic
supplementation for respiratory and gastrointestinal illness symptoms in healthy
physically active individuals - Clin Nutr. 2013 Oct 10 -
"Four hundred and sixty five participants (241 males;
age 35 ± 12 y (mean ± SD) and 224 females; age 36 ± 12 y) were assigned to one
of three groups: Group 1 - Bifidobacterium animalis subsp. lactis Bl-04 (Bl-04)
2.0 × 109colony forming units per day, CFU per day, Group 2 - Lactobacillus
acidophilus NCFM and Bifidobacterium animalis subsp. lactis Bi-07 (NCFM & Bi-07)
5 × 109 CFU each per day) or Group 3 - placebo mixed in a drink ... The risk of
an upper respiratory illness episode was significantly lower in the Bl-04 group
(hazard ratio 0.73; 95% confidence interval 0.55-0.95; P = 0.022) compared to
placebo. There was no significant difference in illness risk between the NCFM &
Bi-07 group (hazard ratio 0.81; 0.62-1.08; P = 0.15) and the placebo group.
There was a 0.7 and 0.9 month delay in the median time to an illness episode in
the Bl-04 and NCFM & Bi-07 groups respectively compared to placebo (placebo 2.5
months; Bl-04 3.2 months; NCFM & Bi-07 3.4 months). There were insufficient GI
illness episodes for analysis" - See
Bifidobacterium animalis products at iHerb.
- Activia - Wikipedia,
the free encyclopedia - "Activia products thus
contain Bifidobacterium animalis DN 173,010, a proprietary strain of
Bifidobacterium, a probiotic which is marketed by Dannon under the trade
names Bifidus Regularis, Bifidus Actiregularis, Bifidus Digestivum and
Bifidobacterium Lactis" - See my yogurt recipe which is made with
Activia on my yogurt page.
-
Dairy Foods
and Dairy Protein Consumption Is Inversely Related to Markers of Adiposity in
Obese Men and Women - Nutrients. 2013 Nov 20;5(11):4665-4684 -
"We sought to examine relationships between energy,
protein and calcium consumption from dairy foods (milk, yoghurt, cheese, dairy
spreads, ice-cream) and adiposity including body mass index (BMI), waist (WC)
and hip circumference (HC), and direct measures of body composition using dual
energy X-ray absorptiometry (% body fat and abdominal fat) in an opportunistic
sample of 720 overweight/obese Australian men and women ... Overall dairy food
consumption (g/day) was inversely associated with BMI, % body fat and WC (all p
< 0.05). Dairy protein and dairy calcium (g/day) were both inversely associated
with all adiposity measures (all p < 0.05). Yoghurt consumption (g/day) was
inversely associated with % body fat, abdominal fat, WC and HC (all p < 0.05),
while reduced fat milk consumption was inversely associated with BMI, WC, HC and
% body fat (all p < 0.05). Within a sample of obese adults, consumption of dairy
products, dairy protein, and calcium was associated with more favourable body
composition"
-
Dairy
products and the risk of type 2 diabetes: a systematic review and dose-response
meta-analysis of cohort studies - Am J Clin Nutr. 2013 Aug 14 -
"searched the PubMed database for prospective cohort
and nested case-control studies of dairy product intake and risk of type 2
diabetes up to 5 June 2013 ... the summary RRs (95% CIs) were 0.93 (0.87, 0.99;
I2 = 33%) per 400 g total dairy products/d (n = 12), 0.98 (0.94, 1.03; I2 = 8%)
per 200 g high-fat dairy products/d (n = 9), 0.91 (0.86, 0.96; I2 = 40%) per 200
g low-fat dairy products/d (n = 9), 0.87 (0.72, 1.04; I2 = 94%) per 200 g milk/d
(n = 7), 0.92 (0.86, 0.99; I2 = 0%) per 50 g cheese/d (n = 8), and 0.78 (0.60,
1.02; I2 = 70%) per 200 g yogurt/d (n = 7) ... This meta-analysis suggests that
there is a significant inverse association between intakes of dairy products,
low-fat dairy products, and cheese and risk of type 2 diabetes" - Note:
Yogurt was the most protective at .78 per 200 grams. 200 grams is 7 ounces.
-
Effects
of synbiotic food consumption on metabolic status of diabetic patients: A
double-blind randomized cross-over controlled clinical trial - Clin
Nutr. 2013 Jun 7 - "This randomized double-blinded
cross-over controlled clinical trial was performed among 62 diabetic
patients aged 35-70 y. After a 2-wk run-in period, subjects were randomly
assigned to consume either a synbiotic (n = 62) or control food (n = 62) for
6 weeks ... The synbiotic food consisted of a probiotic viable and
heat-resistant Lactobacillus sporogenes (1 × 107 CFU), 0.04 g inulin (HPX)
as prebiotic with 0.38 g isomalt, 0.36 g sorbitol and 0.05 g stevia as
sweetener per 1 g. Control food (the same substance without probiotic
bacteria and prebiotic inulin) was packed in identical 9-gram packages.
Patients were asked to consume the synbiotic and control foods three times a
day ... In conclusion, consumption of a synbiotic food for 6 weeks among
diabetic patients had significant effects on serum insulin, hs-CRP, uric
acid and plasma total GSH levels" - Note: I not sure whether they
are talking about probiotic supplements
added to the food or something like yogurt. See
probiotic products at Amazon.com
and my yogurt recipe at the top of my Yogurt Page.
-
Effects
of low-fat or full-fat fermented and non-fermented dairy foods on selected
cardiovascular biomarkers in overweight adults - Br J Nutr. 2013 Jun
12:1-8 - "In a randomised cross-over study, twelve
overweight/obese subjects consumed during two 3-week periods two full-fat
dairy diets containing either yogurt plus cheese (fermented) or butter,
cream and ice cream (non-fermented) or a low-fat milk plus yogurt diet, with
the latter being consumed between and at the end of the full-fat dairy
dietary periods ... In conclusion, short-term diets containing low-fat dairy
products did not lead to a more favourable biomarker profile associated with
CVD risk compared with the full-fat dairy products, suggesting that full-fat
fermented dairy products may be the more favourable"
-
Cholesterol-lowering efficacy of a microencapsulated bile salt
hydrolase-active Lactobacillus reuteri NCIMB 30242 yoghurt formulation in
hypercholesterolaemic adults - Br J Nutr. 2011 Nov 9:1-9 -
"Over the intervention period, subjects consuming
yoghurts containing microencapsulated L. reuteri NCIMB 30242 attained
significant reductions in LDL-cholesterol (LDL-C) of 8.92 % (P = 0.016),
total cholesterol (TC) of 4.81 % (P = 0.031) and non-HDL-cholesterol (HDL-C)
of 6.01 % (P = 0.029) over placebo, and a significant absolute change in
apoB-100 of - 0.19 mmol/l (P = 0.049). Serum concentrations of TAG and HDL-C
were unchanged over the course of the study. Present results show that
consumption of microencapsulated BSH-active L. reuteri NCIMB 30242 yoghurt
is efficacious and safe for lowering LDL-C, TC, apoB-100 and non-HDL-C in
hypercholesterolaemic subjects. The efficacy of microencapsulated BSH-active
L. reuteri NCIMB 30242 yoghurts appears to be superior to traditional
probiotic therapy and akin to that of other cholesterol-lowering
ingredients"
-
A Diet
High in Low-Fat Dairy Products Lowers Diabetes Risk in Postmenopausal Women
- J Nutr. 2011 Sep 21 - "After multivariable
adjustment, low-fat dairy product consumption was inversely associated with
the risk of type 2 diabetes. RR was roughly 0.5-0.6 in the upper quintiles
compared with the lowest quintile (median servings/d, 2.8 in the 5th
quintile and 1.5 in the 4th quintile vs. 0.05 in the first quintile; P-trend
< 0.001). The inverse relationship was more pronounced in women with a
higher BMI. High yogurt consumption was associated with a significant
decrease in diabetes risk, whereas there was no relationship between
high-fat dairy product consumption and diabetes risk"
-
Increased Consumption of Dairy Foods and Protein during Diet- and
Exercise-Induced Weight Loss Promotes Fat Mass Loss and Lean Mass Gain in
Overweight and Obese Premenopausal Women - J Nutr. 2011 Jul 20 -
"Weight loss can have substantial health benefits
for overweight or obese persons; however, the ratio of fat:lean tissue loss
may be more important. We aimed to determine how daily exercise (resistance
and/or aerobic) and a hypoenergetic diet varying in protein and calcium
content from dairy foods would affect the composition of weight lost in
otherwise healthy, premenopausal, overweight, and obese women. Ninety
participants were randomized to 3 groups (n = 30/group): high protein, high
dairy (HPHD), adequate protein, medium dairy (APMD), and adequate protein,
low dairy (APLD) differing in the quantity of total dietary protein and
dairy food-source protein consumed: 30 and 15%, 15 and 7.5%, or 15 and <2%
of energy, respectively. Body composition was measured by DXA at 0, 8, and
16 wk and MRI (n = 39) to assess visceral adipose tissue (VAT) volume at 0
and 16 wk. All groups lost body weight (P < 0.05) and fat (P < 0.01);
however, fat loss during wk 8-16 was greater in the HPHD group than in the
APMD and APLD groups (P < 0.05). The HPHD group gained lean tissue with a
greater increase during 8-16 wk than the APMD group, which maintained lean
mass and the APLD group, which lost lean mass (P < 0.05). The HPHD group
also lost more VAT as assessed by MRI (P < 0.05) and trunk fat as assessed
by DXA (P < 0.005) than the APLD group. The reduction in VAT in all groups
was correlated with intakes of calcium (r = 0.40; P < 0.05) and protein (r =
0.32; P < 0.05). Therefore, diet- and exercise-induced weight loss with
higher protein and increased dairy product intakes promotes more favorable
body composition changes in women characterized by greater total and
visceral fat loss and lean mass gain"
-
Effect
of functional yogurt NY-YP901 in improving the trait of metabolic syndrome
- Eur J Clin Nutr. 2011 Jun 22 - "This study was
aimed to assess the beneficial effects on metabolic syndrome of functional
yogurt NY-YP901 (Namyang Dairy Product Co. Ltd and Nutra R&BT Inc., Seoul,
Korea) supplemented with mixture of Streptococcus thermophilus,
Lactobacillus acidophilus, Bifidobacterium infantis and extra-ingredients
containing Bifidobacterium breve (CBG-C2), Enterococcus faecalis FK-23,
fibersol-2 and so on ... In the treatment group consuming NY-YP901,
statistically significant beneficial changes were observed in body weight
(treatment group vs control group=-0.24+/-1.50 vs +0.64+/-1.39 kg, P<0.05),
BMI (-0.10+/-0.58 vs +0.24+/-0.50 kg/m(2), P<0.05 ) and low-density
lipoprotein (LDL)-cholesterol (-7.71+/-14.14 vs -0.43+/-15.32 mg/dl, P<0.05)
after 8 weeks. The change in other parameters was not different between the
treatment and the control groups.Conclusions:The functional yogurt NY-YP901
reduced LDL-cholesterol, body weight and BMI in the subjects at a 300-ml
consumption daily for 8 weeks. From these findings, regular intake of
functional yogurt NY-YP901 may be consequently related to improve metabolic
syndrome" - So how does that compare as far as active culture to what
you actually be able to buy in a local store in the U.S.:
-
Activia Ingredients - livestrong.com -
"Activia has Lactobacillus bulgaricus, Streptococcus thermophilus and
Bifidobacteria lactis, also known as Bifidobacteria regularis"
-
Association between yogurt, milk, and cheese consumption and common carotid
artery intima-media thickness and cardiovascular disease risk factors in
elderly women - Am J Clin Nutr. 2011 May 25 -
"Total dairy product, milk, and cheese consumption was not associated with
CCA-IMT (P > 0.05), whereas yogurt consumption was negatively associated
with CCA-IMT (unadjusted standardized β = -0.081, P = 0.008; baseline risk
factor-adjusted standardized β = -0.075, P = 0.015). Participants who
consumed >100 g yogurt/d had a significantly lower CCA-IMT than did
participants with lower consumption (unadjusted = -0.024 mm, P = 0.002).
This relation remained significant after adjustment for baseline, dietary,
and lifestyle risk factors (multivariable analysis = -0.023 mm, P = 0.003)
... Increased consumption of yogurt, but not of other dairy products, is
associated with a lower CCA-IMT, independent of other risk factors"
-
Dairy
consumption and risk of type 2 diabetes mellitus: a meta-analysis of cohort
studies - Eur J Clin Nutr. 2011 May 11 - "A
combined RR of 0.86 (95% confidence interval (CI), 0.79-0.92) was revealed
on T2DM risk associated to dairy intake, with little evidence of
heterogeneity. For subgroup analysis, a combined RR was 0.82 (95% CI,
0.74-0.90), 1.00 (95% CI, 0.89-1.10), 0.95 (95% CI, 0.86-1.05) and 0.83 (95%
CI, 0.74-0.93) for the intake of low-fat dairy, high-fat dairy, whole milk
and yogurt, respectively. Dose-response analysis showed that T2DM risk could
be reduced 5% for total dairy products and 10% for low-fat dairy products.
Conclusion: An inverse association of daily intake of dairy products,
especially low-fat dairy, with T2DM was revealed, indicating a beneficial
effect of dairy consumption in the prevention of T2DM development"
-
Yogurt
consumption and risk of colorectal cancer in the italian EPIC cohort - Int J
Cancer. 2011 May 23 - "Yogurt intake was inversely
associated with CRC risk. For the energy-adjusted model, HR for CRC in the
highest vs. lowest tertile of yogurt intake was 0.62 (95%CI, 0.46-0.83). In the
full model adjusted for energy, simple sugar, calcium, fiber, animal fat,
alcohol, and red meat intake, as well as body mass index, smoking, education and
physical activity, HR was 0.65 (95%CI, 0.48-0.89) in the highest vs. lowest
tertile. The protective effect of yogurt was evident in the entire cohort, but
was stronger in men, although there was no interaction of sex with the
yogurt-CRC association (P-interaction 0.20, fully-adjusted model). In this
prospective study, high yogurt intake was significantly associated with
decreased CRC risk, suggesting that yogurt should be part of a diet to prevent
the disease"
-
Cultured
milk, yogurt, and dairy intake in relation to bladder cancer risk in a
prospective study of Swedish women and men - Am J Clin Nutr. 2008
Oct;88(4):1083-7 - "Total dairy intake was not
significantly associated with risk of bladder cancer [> or =7.0 servings/d
compared with < 3.5 servings/d: multivariate rate ratio (RR) = 0.87; 95% CI:
0.66, 1.15; P for trend = 0.33]. However, a statistically significant
inverse association was observed for the intake of cultured milk (sour milk
and yogurt). The multivariate RRs for the highest category of cultured milk
intake (> or =2 servings/d) compared with the lowest category (0 serving/d)
were 0.62 (95% CI: 0.46, 0.85; P for trend = 0.006) in women and men
combined, 0.55 (95% CI: 0.25, 1.22; P for trend = 0.06) in women, and 0.64
(95% CI: 0.46, 0.89; P for trend = 0.03) in men. The intake of milk or
cheese was not associated with bladder cancer risk ... These findings
suggest that a high intake of cultured milk may lower the risk of developing
bladder cancer"
-
Effects of ingesting Lactobacillus- and Bifidobacterium-containing yogurt in
subjects with colonized Helicobacter pylori - Am J Clin Nutr. 2004
Sep;80(3):737-41 - "Regular intake of yogurt containing
Bb12 and La5 effectively suppressed H. pylori infection in humans"
|
|