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Home > Health
Conditions > Claudication.
Claudication
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Intermittent Claudication
- Vitacost Health Library
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Chronic Venous Insufficiency
- Vitacost Health Library
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Claudication
- The Natural Pharmacist
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Do you have any product suggestions for someone who suffers from
intermittent claudication? - Life Extension Magazine, 12/03
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The Best Kept Secret in Heart Health - Natural Foods Merchandiser, 11/03
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"There's a lot of material in the scientific
journals [on carnitine's benefit for] intermittent claudication
[atherosclerosis-induced leg pain], angina pectoris [chest pain] and
congestive heart failure ... individuals with intermittent claudication
experienced a 73 percent improvement in walking distance when they took 2
grams of carnitine daily"
- Policosanol more
Effective than Lovastatin for Intermittent Claudication - New Hope
Natural Media, 5/29/03 -
"Those taking
policosanol had a 34% increase in pain-free walking distance, while no
change was observed in those taking lovastatin.
Quality of life was also reported as being significantly better in the
policosanol group compared with the lovastatin group. Both treatment groups
had significant reductions in total cholesterol and LDL cholesterol.
However, participants taking policosanol had a significant 32% increase in
HDL cholesterol and a 6% decrease in fibrinogen, while these parameters
remained unchanged in those receiving lovastatin" - See
iHerb or
Vitacost
policosanol products. Claudication gets my attention because my father has
it and if there is a hereditary factor, I want to prevent it. - Ben
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Natural
products to lower cholesterol levels - Don't forget niacin - Dr.
Murray's Newsletter , 4/23/03 -
"The percentage increase in HDL
cholesterol, a more significant indicator for coronary heart disease,
was dramatically in favor of niacin (33 vs. 7%).
Equally as impressive was the percentage decrease in Lp(a) for niacin. While
niacin produced a 35% reduction in Lp(a) lipoprotein levels,
lovastatin did not produce any effect. Other studies have shown that
niacin can lower Lp(a) levels by an average of 38% ... Another approach to
reduce flushing is to use inositol
hexaniacinate. This form of niacin has long been used in Europe to lower
cholesterol levels and also to improve blood flow in intermittent
claudication - a peripheral vascular disease that is quite common in
diabetes. It yields slightly better clinical results than standard niacin,
but is much better tolerated, in terms of both flushing and, more
importantly, long-term side-effects"
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L-Carnitine Aids Circulation in Legs - Nutrition Science News, 12/01
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Cuban Lipid Crisis - Nutrition Science News, 11/01 -
"Policosanol is similar in function and potency to
some statin drugs ... After using 10 mg/day policosanol for two years, study
participants tripled their treadmill walking distance. The placebo group
experienced insignificant change"
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A long-term study of policosanol in the treatment of intermittent
claudication - Angiology 2001 Feb;52(2):115-125 -
"After 6 months of therapy, policosanol significantly
increased (p < 0.01) the initial claudication distance from 125.9 +/- 8.7 m
to 201.1 +/- 24.8 m and the absolute claudication distance from 219.5 +/-
14.1 m to 380.7 +/- 50.2 m. Both variables remained unchanged in the placebo
group (p < 0.01). These effects did not wear off but improved after
long-term therapy, so that final values were 333.5 +/- 28.6 m (initial
claudication distance) and 648.9 +/- 54.1 m (absolute claudication
distance); both significantly greater (p < 0.0001) than those obtained in
the placebo group, which showed values of 137.9 +/- 21.8 m (initial
claudication distance) and 237.7 +/- 28.1 m (absolute claudication
distance), respectively"
- Ginkgo Biloba May
Help Some With Painful Leg Cramps - WebMD, 3/30/00
C
Other News:
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It is
never too late to start statins for clogged leg arteries - Science Daily,
9/3/19 - "Around 200 million people worldwide have
peripheral arterial disease (PAD), a condition in which arteries in the legs
are clogged. This restricts blood flow to the legs and raises the chances of
stroke and heart attack. Around 30% of patients have pain and cramping in
their legs when they walk -- referred to as intermittent claudication --
while others have gangrene in the feet due to poor circulation ... This
study examined whether adherence to statin therapy influenced survival in
patients with symptomatic PAD ... The dose of drug also increased between
the two time periods, which was paralleled by a significant drop in LDL
cholesterol from 97 to 82 mg/dL ... Patients who stopped taking a statin had
a similar mortality rate (33%) to those who never took the drug (34%).
Adhering to statins throughout the 50 months was linked with a 20% rate of
death ... Taking high-dose statins throughout the study was linked with the
lowest mortality rate (10%), while reducing the dosage during the study was
related to the highest death rate (43%) ... All PAD patients should take
statins, preferably very potent statins, like rosuvastatin 40 mg or
atorvastatin 80 mg, or at the highest tolerable dose. In the rare case of
statin intolerance, which was around 2% in our study, alternative lipid
lowering therapies must be considered"
- Doctors try again to fight
clogged leg arteries - MSNBC, 8/31/04
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Cryoplasty Treatment Beneficial for In-stent Restenosis in Lower Extremities
- Doctor's Guide, 3/29/04
- New Treatment
Stops Claudication Leg Pain - WebMD, 3/29/04
- Cholesterol
Drug May Ease Intermittent Claudication - WebMD, 9/2/03 -
"Lipitor has the added
benefit of improving walking ability in people with intermittent
claudication, a condition caused by blocked leg arteries that leads to
cramping and fatigue in the legs and buttocks during exercise, such as
walking"
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Statin, Atorvastatin, Increases Pain-Free Walking Distance In Patients With
Intermittent Claudication - Doctor's Guide, 9/2/03
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Cilostazol Effective For Claudication In Both Diabetics And Non-Diabetics
- Doctor's Guide, 2/11/03
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Potassium Administration Helps Leg Blood Flow in Heart Failure Patients
- Doctor's Guide, 11/19/02
- Fibroblast Growth
Factor Improves Severe Claudication - Medscape, 6/14/02
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Angiogenic Therapy Appears To Reduce Claudication - Doctor's Guide,
6/13/02
- Exercise Tolerance
Increased With Angiogenesis Drugs In Angina And Peripheral Artery Disease
Patients - Doctor's Guide, 3/20/01
- Pletal (Cilostazol) More
Effective In Relieving Leg Pain Than Trental (Pentoxifylline) - Doctor's
Guide, 10/27/00
- FDA Approves Pletal For
Intermittent Claudication - Doctor's Guide, 1/18/99
- Study Shows Zocor Reduces
Risk Of Stroke - Doctor's Guide, 2/2/98 -
"The drug was also shown to reduce the development
of new or worsened signs and symptoms of reduced blood flow in the legs -- a
painful condition known as claudication -- by 38 percent. Claudication is
caused by a narrowing of the arteries in the leg resulting from an
accumulation of cholesterol plaque, or fat deposits and often occurs in
smokers"
- Clopidogrel Demonstrates
Superior Benefit in Patients at Risk of Stroke - Doctor's Guide,
11/13/96
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