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Anti-aging Research > Ammonia Scavengers.
Popular supplements to remove ammonia:
supplementation to reverse hyperammonemia in a patient undergoing chronic
valproic acid treatment: A case report - J Int Med Res. 2017 Jan 1 -
"Carnitine supplementation was useful for reversal
of her hyperammonemia, allowing her to continue valproic acid for seizure
control" - See
L-carnitine at Amazon.com.
Probiotics found to reduce hepatic encephalopathy - Science Daily,
4/25/13 - "Ammonia, produced by gut bacteria, is
thought to be one of the main mediators of cerebral dysfunction in HE.
Probiotics work by enriching the gut flora with a non-urease producing
microorganisms, which decrease ammonia production ... Twice as many patients
taking a placebo developed overt HE (the study's primary endpoint) compared
to patients taking probiotics in the form of a capsule ... Hepatic
encephalopathy is an insidious disease that's caused by an accumulation of
toxins in the blood that are normally removed by the liver ... Hepatic
encephalopathy is a spectrum of neuropsychiatric abnormalities including
personality changes, intellectual impairment and reduced levels of
consciousness in patients with liver failure, after exclusion of other known
brain disease" - See
Garden of Life Primal Defense HSO Probiotic Formula at Amazon.com.
News & Research:
FDA Approves Drug to Treat Hyperammonemi - Doctor's Guide, 3/18/10
- Researchers Warn:
Ammonia Levels May Increase After Lung Transplant Surgery - Doctor's
Ammonia accumulation during highly intensive long-lasting cycling:
individual observations - Int J Sports Med. 1990 May;11 Suppl 2:S78-84 -
"Acute quantitative ammonia production during
intensive endurance exercise may be enhanced by a reduced glycogen
availability in muscle. However, adequate amounts of glycogen itself do not
prevent ammonia production when exercise is at high intensity and
long-lasting. The continuous ammonia accumulation in blood during endurance
exercise in trained individuals may be the result of a relatively low blood
flow to the liver and thereby low clearance in contrast to lactate which may
not accumulate due to a high clearance rate in both active and nonactive
oxidative muscle fibers. In a number of subjects it was observed that
exhaustion, when performing endurance exercise at high exercise intensities,
occurred when plasma ammonia levels were high. Muscle cramps occurred in
subjects who reached their highest individual ammonia values and seemed not
to be related to serum potassium, plasma lactate, or muscle glycogen. These
individual observations give rise to the hypothesis that high intramuscular
ammonia levels may be related to the etiology of muscle exhaustion and
muscle cramping during highly intensive endurance exercise"
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