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Home > Anti-aging Research > Antibiotics.

Antibiotics and Antibacterial

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  • Lactoferrin modulates gut microbiota and Toll-like receptors (TLRs) in mice with dysbiosis induced by antibiotics - Food Funct 2022 May 1 - "Antibiotic administration can result in gut microbiota and immune system alterations that impact health. Bovine lactoferrin is a milk protein with anticancer, anti-inflammatory, antimicrobial and immune modulatory activities ... In a situation of intestinal dysbiosis induced by clindamycin, lactoferrin restores the normal levels of some anti-inflammatory bacteria and TLRs and, therefore, could be a good ingredient to be added to functional foods" - See lactoferrin at Amazon.com.
  • Probiotic Lactobacillus reuteri Prevents Postantibiotic Bone Loss by Reducing Intestinal Dysbiosis and Preventing Barrier Disruption - J Bone Miner Res. 2019 Jan 28 - "Antibiotic treatment, commonly prescribed for bacterial infections, depletes and subsequently causes long-term alterations in intestinal microbiota composition. Knowing the importance of the microbiome in the regulation of bone density, we investigated the effect of postantibiotic treatment on gut and bone health ... A link between the microbiome composition and bone density was demonstrated by supplementing the mice with probiotic bacteria. Specifically, Lactobacillus reuteri, but not Lactobacillus rhamnosus GG or nonpathogenic Escherichia coli, reduced the postantibiotic elevation of the Firmicutes:Bacteroidetes ratio and prevented femoral and vertebral trabecular bone loss. Consistent with causing bone loss, postantibiotic-induced dysbiosis decreased osteoblast and increased osteoclast activities, changes that were prevented by both L. reuteri and MDY. These data underscore the importance of microbial dysbiosis in the regulation of intestinal permeability and bone health, as well as identify L. reuteri and MDY as novel therapies for preventing these adverse effects" - See probiotic products at Amazon.com.
  • Older Age, Long-term Antibiotic Use Linked to Mortality Risk - Medscape, 4/2/18 - "women who used antibiotics for 2 months or longer were 27% more likely to die of all causes and were as much as 57% more likely to die of cardiovascular causes compared with those with no antibiotic use ... Antibiotic use has been linked with changes to the gut microbiome that can in fact last for years, while infections from antibiotic resistances remain an ever-increasing concern" - See  probiotic products at Amazon.com.
  • Probiotics Prevent Diarrhea Related to Antibiotic Use, Review Shows - Science Daily, 5/30/13 - "Antibiotics disturb the beneficial bacteria that live in the gut and allow other harmful bacteria like C. difficile to take hold. Although some people infected with C. difficile show no symptoms, others suffer diarrhea or colitis. The so-called "good bacteria" or yeast in probiotic foods and supplements may offer a safe, low-cost way to help prevent C. difficile-associated diarrhea (CDAD). This finding is important because CDAD is expensive to treat ... Probiotics taken in conjunction with antibiotics reduced the number of people who suffered diarrhea by 64%" - See probiotic products at Amazon.com.
  • Probiotics Reduce Antibiotic Diarrhea - Science Daily, 5/8/12 - "Diarrhea is a common side effect of antibiotic use, occurring in almost 1 in 3 people who take the drugs ... By affecting good bacteria, as well as bad, antibiotics can disrupt the delicate microbial balance in the intestines, but the live microorganisms marketed as probiotics can help restore this balance to reduce diarrhea risk ... in people taking antibiotics, those who used probiotics were 42% less likely to develop diarrhea" - See probiotics at Amazon.com.
  • Some Doctors Warming Up to Probiotics - WebMD, 11/4/11 - "A review of 22 studies involving 3,096 patients presented at the meeting showed that taking probiotics while on antibiotics may cut the risk of developing antibiotic-associated diarrhea by about 60% ...antibiotics kill "good" bacteria along with the bacteria that cause illness. A decrease in beneficial bacteria may lead to digestive problems. Taking probiotics may help replace the lost beneficial bacteria and help prevent diarrhea ... Probiotics also appeared to provide protection against potentially deadly bouts of diarrhea caused by the bug Clostridium difficile, or C. diff. ... Look for a brand you trust and whose label offers that information" - See probiotics at Amazon.com.
  • Antibiotics Take Toll On Beneficial Microbes In Gut - Science Daily, 6/18/09 - "Normally, a set of thousands of different kinds of microbes lives in the gut – a distinctive mix for each person, and thought to be passed on from mother to baby. The microbes, including many different bacteria, aid digestion and nutrition, appear to help maintain a healthy immune system, and keep order when harmful microbes invade ... Mice, which normally develop a diverse set of microbes after being born without one, then were given either cefoperazone, a broad-spectrum cephalosporin antibiotic, or a combination of three antibiotics (amoxicillin, bismuth and metronidazole) ... Both antibiotic treatments caused significant changes in the gut microbial community. However, in the mice given cefoperazone, there was no recovery of normal diversity. In other mice given the amoxicillin-containing combination, the microbiota largely recovered, but not completely ... Probiotics may be part of the solution, but we don’t know that yet" - See probiotics at Amazon.com.
  • Probiotics May Help People Taking Antibiotics - Science Daily, 12/17/08 - "Up to one in five people on antibiotics stop taking their full course of antibiotic therapy due to diarrhea. Physicians could help patients avoid this problem by prescribing probiotics" - See probiotics at Amazon.com.
  • Green Tea Helps Beat Superbugs, Study Suggests - Science Daily, 3/30/08 - "drinking green tea helps the action of important antibiotics in their fight against resistant superbugs, making them up to three times more effective" - See green tea extract at Amazon.com.
  • Do Alcohol and Antibiotics Mix? - Dr. Weil, 14/9/04
  • Bacterial Infections - Life Extension Magazine
  • Antibiotic Antidote? - Dr. Weil, 5/20/03

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