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Antibiotics and Antibacterial

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Alternative News:

• Lactoferrin modulates gut microbiota and Toll-like receptors (TLRs) in mice with dysbiosis induced by antibiotics - Food Funct 2022 May 1 - "Antibiotic administration can result in gut microbiota and immune system alterations that impact health. Bovine lactoferrin is a milk protein with anticancer, anti-inflammatory, antimicrobial and immune modulatory activities ... In a situation of intestinal dysbiosis induced by clindamycin, lactoferrin restores the normal levels of some anti-inflammatory bacteria and TLRs and, therefore, could be a good ingredient to be added to functional foods" - See lactoferrin at Amazon.com.
• Probiotic Lactobacillus reuteri Prevents Postantibiotic Bone Loss by Reducing Intestinal Dysbiosis and Preventing Barrier Disruption - J Bone Miner Res. 2019 Jan 28 - "Antibiotic treatment, commonly prescribed for bacterial infections, depletes and subsequently causes long-term alterations in intestinal microbiota composition. Knowing the importance of the microbiome in the regulation of bone density, we investigated the effect of postantibiotic treatment on gut and bone health ... A link between the microbiome composition and bone density was demonstrated by supplementing the mice with probiotic bacteria. Specifically, Lactobacillus reuteri, but not Lactobacillus rhamnosus GG or nonpathogenic Escherichia coli, reduced the postantibiotic elevation of the Firmicutes:Bacteroidetes ratio and prevented femoral and vertebral trabecular bone loss. Consistent with causing bone loss, postantibiotic-induced dysbiosis decreased osteoblast and increased osteoclast activities, changes that were prevented by both L. reuteri and MDY. These data underscore the importance of microbial dysbiosis in the regulation of intestinal permeability and bone health, as well as identify L. reuteri and MDY as novel therapies for preventing these adverse effects" - See probiotic products at Amazon.com.
• Older Age, Long-term Antibiotic Use Linked to Mortality Risk - Medscape, 4/2/18 - "women who used antibiotics for 2 months or longer were 27% more likely to die of all causes and were as much as 57% more likely to die of cardiovascular causes compared with those with no antibiotic use ... Antibiotic use has been linked with changes to the gut microbiome that can in fact last for years, while infections from antibiotic resistances remain an ever-increasing concern" - See  probiotic products at Amazon.com.
• Probiotics Prevent Diarrhea Related to Antibiotic Use, Review Shows - Science Daily, 5/30/13 - "Antibiotics disturb the beneficial bacteria that live in the gut and allow other harmful bacteria like C. difficile to take hold. Although some people infected with C. difficile show no symptoms, others suffer diarrhea or colitis. The so-called "good bacteria" or yeast in probiotic foods and supplements may offer a safe, low-cost way to help prevent C. difficile-associated diarrhea (CDAD). This finding is important because CDAD is expensive to treat ... Probiotics taken in conjunction with antibiotics reduced the number of people who suffered diarrhea by 64%" - See probiotic products at Amazon.com.
• Probiotics Reduce Antibiotic Diarrhea - Science Daily, 5/8/12 - "Diarrhea is a common side effect of antibiotic use, occurring in almost 1 in 3 people who take the drugs ... By affecting good bacteria, as well as bad, antibiotics can disrupt the delicate microbial balance in the intestines, but the live microorganisms marketed as probiotics can help restore this balance to reduce diarrhea risk ... in people taking antibiotics, those who used probiotics were 42% less likely to develop diarrhea" - See probiotics at Amazon.com.
• Some Doctors Warming Up to Probiotics - WebMD, 11/4/11 - "A review of 22 studies involving 3,096 patients presented at the meeting showed that taking probiotics while on antibiotics may cut the risk of developing antibiotic-associated diarrhea by about 60% ...antibiotics kill "good" bacteria along with the bacteria that cause illness. A decrease in beneficial bacteria may lead to digestive problems. Taking probiotics may help replace the lost beneficial bacteria and help prevent diarrhea ... Probiotics also appeared to provide protection against potentially deadly bouts of diarrhea caused by the bug Clostridium difficile, or C. diff. ... Look for a brand you trust and whose label offers that information" - See probiotics at Amazon.com.
• Antibiotics Take Toll On Beneficial Microbes In Gut - Science Daily, 6/18/09 - "Normally, a set of thousands of different kinds of microbes lives in the gut – a distinctive mix for each person, and thought to be passed on from mother to baby. The microbes, including many different bacteria, aid digestion and nutrition, appear to help maintain a healthy immune system, and keep order when harmful microbes invade ... Mice, which normally develop a diverse set of microbes after being born without one, then were given either cefoperazone, a broad-spectrum cephalosporin antibiotic, or a combination of three antibiotics (amoxicillin, bismuth and metronidazole) ... Both antibiotic treatments caused significant changes in the gut microbial community. However, in the mice given cefoperazone, there was no recovery of normal diversity. In other mice given the amoxicillin-containing combination, the microbiota largely recovered, but not completely ... Probiotics may be part of the solution, but we don’t know that yet" - See probiotics at Amazon.com.
• Probiotics May Help People Taking Antibiotics - Science Daily, 12/17/08 - "Up to one in five people on antibiotics stop taking their full course of antibiotic therapy due to diarrhea. Physicians could help patients avoid this problem by prescribing probiotics" - See probiotics at Amazon.com.
• Green Tea Helps Beat Superbugs, Study Suggests - Science Daily, 3/30/08 - "drinking green tea helps the action of important antibiotics in their fight against resistant superbugs, making them up to three times more effective" - See green tea extract at Amazon.com.
• Do Alcohol and Antibiotics Mix? - Dr. Weil, 14/9/04
• Bacterial Infections - Life Extension Magazine
• Antibiotic Antidote? - Dr. Weil, 5/20/03

Other News:

• Antibiotics wreak havoc on athletic performance - Science Daily, 6/1/22 - "by killing essential gut bacteria, antibiotics ravage athletes' motivation and endurance ... when wheel running in the athletic mice was reduced by 21 percent, researchers were certain the microbiome damage was responsible. In addition, the high runner mice did not recover their running behavior even 12 days after the antibiotic treatment stopped" - See probiotic supplements at Amazon.com.
• Antibiotic Use in Midlife Ups Risk of Cognitive Decline - Medscape, 4/1/22 - "scientists paired self-reported antibiotic use of 14,000 middle-aged nurses with outcomes on neuropsychological tests conducted 7 years later. The results revealed that those nurses who took antibiotics for at least 2 months during a period of 4 years had lower scores on tasks involving memory, learning, attention, and psychomotor speed. Overall, the negative effects of antibiotics on cognition were comparable to those caused by 3 to 4 years of aging"
• Antibiotics linked to increased risk of colon cancer - Science Daily, 9/1/21 - "women and men who took antibiotics for over six months ran a 17 per cent greater risk of developing cancer in the ascending colon, the first part of the colon to be reached by food after the small intestine, than those who were not prescribed any antibiotics. However, no increased risk was found for cancer in the descending colon. Nor was there an increased risk of rectal cancer in men taking antibiotics, while women taking antibiotics had a slightly reduced incidence of rectal cancer ... The increased risk of colon cancer was visible already five to ten years after taking antibiotics. Although the increase in risk was greatest for those taking most antibiotics, it was also possible to observe an admittedly small, but statistically significant, increase in the risk of cancer after a single course of antibiotics"
• Antibiotics in early life could affect brain development - Science Daily, 7/14/21 - "The study compared mice that were exposed to low-dose penicillin in utero or immediately after birth to those that were not exposed. They found that mice given penicillin experienced substantial changes in their intestinal microbiota and had altered gene expression in the frontal cortex and amygdala, two key areas in the brain responsible for the development of memory as well as fear and stress responses"
• Antibiotic Link to Rise in Early Onset Colon Cancer? - Medscape, 7/5/21 - "The team conducted a nested case-control study using data from primary care in Scotland, which involved almost 8000 cases of CRC and over 30,000 healthy controls ... The analysis suggests that a history of antibiotic use among individuals younger than 50 appeared to increase the risk of developing colon cancer (but not rectal) by 49%."
• Increased use of antibiotics may predispose to Parkinson's disease - Science Daily, 11/22/19 - "The strongest associations were found for broad spectrum antibiotics and those that act against against anaerobic bacteria and fungi. The timing of antibiotic exposure also seemed to matter ... The study suggests that excessive use of certain antibiotics can predispose to Parkinson's disease with a delay of up to 10 to 15 years. This connection may be explained by their disruptive effects on the gut microbial ecosystem" - See probiotic supplements at Amazon.com.
• Commonly used antibiotics may lead to heart problems - Science Daily, 9/10/19 - "current users of fluoroquinolone antibiotics, such as Ciprofloxacin or Cipro, face a 2.4 times greater risk of developing aortic and mitral regurgitation, where the blood backflows into the heart, compared to patients who take amoxicillin, a different type of antibiotic. The greatest risk is within 30 days of use"
• Antibiotic Use and Increased Risk of Colon Cancer - Medscape, 8/21/19 - "Even a single course of antibiotics was found to be associated with an increase in the risk of developing colon cancer nearly a decade later ... oral exposure to anti-anaerobic antibiotics produced the most significant effect on colon cancer risk is intriguing ... these agents "markedly disrupt" the gut microbiome, which is predominantly composed of anaerobes ... The primary message of this study is the importance of antibiotic stewardship: not treating common viral infections with antibiotics, using them for the shortest time period possible, and using targeted antibiotics rather than broad spectrum ones"
• Study: Dentists Prescribe Antibiotics Far Too Often - WebMD, 6/5/19 - "Antibiotics have been recommended to dental patients who have certain heart conditions to prevent mouth bacteria from infecting the heart ... But antibiotics can cause serious side effects and contribute to the growing problem of antibiotic resistance ... In the Northeast, 78% of the prescriptions were unnecessary, as were 83% in the Midwest and 80% in the South"
• Antibiotics destroy 'good bacteria' and worsen oral infection - Science Daily, 9/25/18 - "What we found was that antibiotics can kill short-chain fatty acids produced by body's own good bacteria ... We have good bacteria doing good work every day, why kill them? ... As is the case with many infections, if you leave them alone, they will leave on their own"
• Oral Antibiotics May Increase Risk for Kidney Stones - Medscape, 3/10/18 - "Looking at 12 classes of antibiotics, the investigators found an association between nephrolithiasis risk and five types taken 3 to 12 months before the index kidney stone date. The excess relative risk ranged from 27% for broad-spectrum penicillins to 133% for sulfa drugs"
• Antibiotic Use Linked to Juvenile Arthritis - Medscape, 7/20/15 - "One or more courses of antibiotic therapy was associated with an increased risk of developing JIA when compared with control subjects (adjusted odds ratio [OR], 2.1; 95% confidence interval [CI], 1.2 - 3.5), and "[t]he magnitude of the association increased with additional antibiotic courses." This association was noted after adjusting for matching, previous infection, or other autoimmune disease"
• Gut check: Does a hospital stay set patients up for sepsis by disrupting the body’s microbiome? - Science Daily, 6/1/15 - "We know that a major cause of microbiome disruption is antibiotic use. This study hints -- it does not prove, but it hints -- that profligate use of antibiotics might not just be bad because of antibiotic resistance. Profligate use of antibiotics might also, via the microbiome, put patients at increased risk of both all kinds of other infections, and to having a particularly bad response ('sepsis') to those infections" - Note:  It just seems like even if you go in for minor surgery they give you enough antibiotics via IV to kill an elephant.  See probiotic products at Amazon.com.
• Gut Microbiota Disturbance During Antibiotic Therapy - Medscape, 11/14/13 - "Antibiotic (AB) usage ... The results demonstrate that ABs targeting specific pathogenic infections and diseases may alter gut microbial ecology and interactions with host metabolism at a much higher level than previously assumed"
• Too Many Antibiotics Still Prescribed for Sore Throats, Bronchitis: Studies - WebMD, 10/3/13 - "Antibiotics only work against bacterial infections, and yet they are prescribed at a rate of 60 percent for sore throats and 73 percent for bronchitis, conditions that are typically caused by viruses ... There's plenty of blame to go around ... It's a lot easier to write a prescription than to have a five-minute conversation about why antibiotics aren't necessary ... The vast majority of sore throats, and virtually all of bronchitis [cases], get better on its own ... This leads to more antibiotic-resistant bacteria, and when we do that we don't have the antibiotics when we need them because the body has developed resistance ... There is concern about antibiotic overuse causing super bugs and things we are not going to be able to treat down the line ... I think what's missing from the conversation is the fact that we are prescribing and people are taking a medicine that has nearly a zero chance of helping them and a very real chance of hurting them"
• Effects of antibiotics on gut flora analyzed - Science Daily, 1/9/13 - "In the gut live one trillion bacteria, which are known as microbiota or gut flora, and that have co-evolved in symbiosis with humans. According to this study, treatment with antibiotics can alter this symbiosis from early stages of the treatment. "Although some of the changes are oscillatory and can be reversed at the end of the treatment, others seem irreversible,""
• Antibiotic use in infants before six months associated with being overweight in childhood - Science Daily, 8/21/12 - "on average, children exposed to antibiotics from birth to 5 months of age weighed more for their height than children who weren't exposed. Between the ages of 10 to 20 months, this translated into small increases in body mass percentile, based on models that incorporated the potential impacts of diet, physical activity, and parental obesity. By 38 months of age, exposed children had a 22% greater likelihood of being overweight. However, the timing of exposure mattered: children exposed from 6 months to 14 months did not have significantly higher body mass than children who did not receive antibiotics in that same time period"
• Common antibiotics pose a rare risk of severe liver injury in older patients - Science Daily, 8/13/12 - "Compared with clarithromycin, moxifloxacin was associated with a more than 2-fold increased risk of admission to hospital for acute liver injury ... Levofloxacin was also associated with a statistically significant but lower risk of hepatotoxicity than…moxifloxacin"
• Kill the germs, spare the ears: Encouraging study shows how - Science Daily, 6/11/12 - "a team from Switzerland, England and the University of Michigan show apramycin's high efficacy against bacteria, and low potential for causing hearing loss, through a broad range of tests in animals ... The research aims to overcome a serious limitation of aminoglycoside antibiotics, a class of drugs which includes the widely used kanamycin, gentamicin and amikacin ... While great at stopping bacterial infections, these drugs also cause permanent partial hearing loss in 20 percent of people who take them for a short course, and up to 100 percent of people who take them over months or years ... the drugs produce damaging free radicals inside the hair cells of the inner ear ... The research also lends more evidence to support the use of antioxidants to protect the hearing of patients taking current aminoglycoside antibiotics. Schacht has already led a clinical trial in China that showed a major reduction in hearing loss if aspirin was given at the same time as aminoglycoside antibiotics"
• Antibiotic Overuse May Be Bad for Body's Good Bacteria - WebMD, 8/24/11 - "Antibiotic overuse doesn’t just lead to drug-resistant superbugs, it may also permanently wipe out the body’s good bacteria ... in a developed country like the U.S., the average child gets 10 to 20 courses of antibiotics by age 18 ... doctors often prescribe antibiotics before they know whether an infection is viral or bacterial. If the problem is a virus, antibiotics don't help ... a 2003 study published in the Journal of the American Medical Association showed that doctors prescribed antibiotics for more than 60% of adults with upper respiratory tract infections, which are usually caused by viruses ... Antibiotics, he thinks, may also be contributing to obesity in humans, though Blaser says no one yet understands how ... a child’s risk for inflammatory bowel disease increases with the number of courses of antibiotics taken ... antibiotics may be a factor behind the unexplained rises in allergies, asthma, and type 1 diabetes in children ... There’s really only a limited number of studies that have been done on this so far, but I think we’re going to see more because I think it’s going to be a big deal for us to understand this ... effective probiotics are needed to replace lost good bacteria" - See probiotics at Amazon.com.
• Why long-term antibiotic use increases infection with a mycobacterium - Science Daily, 8/1/11
• Gut bacteria linked to behavior: That anxiety may be in your gut, not in your head - Science Daily, 5/17/11 - "For each person, the gut is home to about 1,000 trillium bacteria with which we live in harmony. These bacteria perform a number of functions vital to health: They harvest energy from the diet, protect against infections and provide nutrition to cells in the gut. Any disruption can result in life-threatening conditions, such as antibiotic-induced colitis from infection with the "superbug" Clostridium difficile ... Working with healthy adult mice, the researchers showed that disrupting the normal bacterial content of the gut with antibiotics produced changes in behaviour; the mice became less cautious or anxious. This change was accompanied by an increase in brain derived neurotrophic factor (BDNF), which has been linked, to depression and anxiety ... When oral antibiotics were discontinued, bacteria in the gut returned to normal. "This was accompanied by restoration of normal behaviour and brain chemistry,""
• C. difficile colonization accompanied by changes in gut microbiota: Study hints at probiotics as treatment - Science Daily, 4/19/11 - "Asymptomatic colonization by Clostridium difficile, absent the use of antibiotics, is common in infants and when it happens changes occur in the composition of the gut microbiota ... The adult human gut is an ecosystem containing several pounds of bacteria, including hundreds of species and more than 100 trillion (100,000,000,000,000) individuals. A healthy microbial ecosystem protects the host against Clostridium difficile, which frequently colonizes the gut after its ecological balance has been disrupted by broad spectrum antibiotics ... Our results suggest that Bifidobacterium species, which are used as probiotics, can participate in that barrier effect against C. difficile" - See probiotics at Amazon.com.
• C. difficile increases risk of death six-fold in patients with inflammatory bowel disease - Science Daily, 4/19/11 - "C. difficile bacteria are present naturally in the gut in around two thirds of children and 3 per cent of adults, but they do not cause problems in healthy people. Broad spectrum antibiotics can cause problems by killing harmless bacteria that usually reside in the gut, allowing C. difficile to flourish and produce toxins that cause diarrhea and fever. The infection is rarely fatal in people who are not already severely ill or elderly; a review published in 2010 estimated the overall mortality rate for patients with C. difficile to be 6 per cent ... IBD patients who contract C. difficile in hospital are six times more likely to die in hospital than patients who are admitted for IBD alone. In the patients followed in the study, the mortality rate for IBD patients with C. difficile at 30 days was 25 per cent, compared with 3 per cent for patients with IBD alone ... IBD patients with C. difficile also stay in hospital for longer, with a median length of stay of 26 days compared with five days, and are almost twice as likely to need gastrointestinal surgery ... At St. George's Hospital, we have seen a 70 per cent reduction in hospital-acquired infections after implementing a range of control measures, such as careful handwashing and reduced use of broad spectrum antibiotics"
• Antibiotics disrupt gut ecology, metabolism - Science Daily, 4/19/11 - "carry several pounds of microbes in our gastro-intestinal tracts. Recent research suggests that this microbial ecosystem plays a variety of critical roles in our health ... antibiotics profoundly disrupt intestinal homeostasis ... Intestinal microbes help us digest our food, provide us with vitamins that we cannot make on our own, and protect us from microbes that make us sick, amongst other things ... administered antibiotics to the mice, to kill off most of their gut microbiota, and analyzed the feces anew ... The levels of 87 percent of the molecules detected had been shifted up or down by factors ranging from 2-fold to 10,000-fold ... the unnecessary use of antibiotics has deleterious effects on human health that were previously unappreciated ... our gut microbes control these important molecules raises the possibility that manipulating these microbes could be used to modulate diseases that have hormonal or metabolic origins (such as inmmunodeficiency, depression, diabetes and others)" - See probiotics at Amazon.com.
• Antibiotics May Make Fighting Flu Harder - Science News, 3/14/11 - "Iwasaki and her colleagues treated mice for a month with four antibiotics commonly given to people with bacterial infections, then infected the rodents with the flu. Antibiotic treatment impaired the mice’s ability to make an important flu-fighting molecule called interleukin-1 beta or IL-1 beta, the researchers found. IL-1 beta is necessary to combat influenza and other viruses ... Gut bacteria are constantly priming the immune system to make IL-1 beta, keeping the immune system vigilant against the flu and other viruses ... Some Lactobacillus bacteria, on the other hand, are known as “friendly” gut bacteria and may play a role in virus defense. Mice treated with an antibiotic called neomycin, which wipes out most types of Lactobacillus bacteria while leaving Sphingomonas bacteria alone, have a hard time fighting the flu" - Note:  It seems to be a common misconception of nearly everyone I know that if you've got a bad case of the flu you need to go to a doctor and get antibiotics when in reality, it probably slows recovery.
• Early antibiotic use can lead to increased risk of childhood asthma, study suggests - Science Daily, 1/27/11 - "When babies are given antibiotics, their risk of developing asthma by age 6 may increase by 50 percent"
• How bacteria keep ahead of vaccines and antibiotics - Science Daily, 1/27/11
• Early Antibiotic Use Linked to Asthma and Allergy at Age 6 Years - Medscape, 1/11/11 - "Children with early antibiotic exposure had an increased risk for asthma, with an adjusted odds ratio (OR) of 1.52 (95% confidence interval [CI], 1.07 - 2.16). In children in whom asthma was first diagnosed after age 3 years, the adjusted OR was 1.66 (95% CI, 0.99 - 2.79). In children who had no history of lower respiratory tract infection before age 1 year, the adjusted OR was 1.66 ... Children with no family history of asthma had an even stronger association of early antibiotic use with subsequent development of asthma (adjusted OR, 1.89; 95% CI, 1.00 - 3.58; P for interaction = .03). Adjusted OR for a positive blood or skin test result for allergy was 1.59"
• Antibiotics have long-term impacts on gut flora - Science Daily, 11/1/10 - "Short courses of antibiotics can leave normal gut bacteria harbouring antibiotic resistance genes for up to two years after treatment"
• How bacteria become resistant to antibiotics - Science Daily, 10/4/10
• High potassium? Check your antibiotic - Science Daily, 7/1/10
• Antibiotic resistance lasts up to a year, primary care patient study finds - Science Daily, 5/18/10
• Evidence of increasing antibiotic resistance - Science Daily, 3/3/10
• Low levels of antibiotics cause multidrug resistance in 'superbugs' - Science Daily, 2/11/10
• Why Some Antibiotic Drugs Pack Such A Punch - WebMD, 8/20/09
• Drug Has Potential to Slow Aging - WebMD, 7/10/09 - "At first, the drug was not readily absorbed into the bloodstream of the mice, so a specialized feed was developed with an encapsulated, timed-release form of rapamycin"
• Antibiotic Delayed Aging in Mice - NYTimes.com, 7/8/09 - "The effectiveness of rapamycin in extending the life of elderly mice was discovered by accident. The researchers found that the mice fed rapamycin were not getting the proper dose in their bloodstream. They reformulated the drug in the form of capsules that fed slow doses to the intestine, but by that time the mice were elderly. Nonetheless, life span increased by 14 percent in the females and 9 percent in the males"
• Antibiotics: Single Largest Class Of Drugs Causing Liver Injury - Science Daily, 12/8/08 - "Antibiotics are the single largest class of agents that cause idiosyncratic drug-induced liver injury (DILI) ... DILI is the most common cause of death from acute liver failure and accounts for approximately 13 percent of cases of acute liver failure in the U.S"
• World Faces Global Pandemic Of Antibiotic Resistance, Experts Warn - Science Daily, 9/18/08
• Scientists Strike Blow In Superbugs Struggle - Science Daily, 12/5/07
• Antibiotics Overprescribed By Doctors, Study Suggests - Science Daily, 9/19/07
• Antibiotic Resistance: Doctors' Antibiotic Prescribing Practices Still Contributing to Problem - Science Daily, 7/26/07
• New Hope For Fighting Antibiotic Resistance - Science Daily, 4/26/07
• FDA Weighs Fate of Antibiotic Ketek - WebMD, 12/14/06
• Antibiotic Gets Stronger Liver Warning - WebMD, 6/29/06
• Are Antibiotics Being Used for Too Long? - Doctor's Guide, 6/9/06
• Antibiotic Linked to Liver Problems - Intelihealth, 5/22/06
• Antibiotic Ketek (Telithromycin) and Possible Association With Liver Failure - Doctor's Guide, 2/7/06
• Ketek (Telithromycin) Linked to Two Cases of Liver Failure and Implicated in a Third Case of Hepatitis - Doctor's Guide, 1/20/06
• Antibiotics: Overused for Sore Throats? - WebMD, 11/8/06
• Children Overprescribed Antibiotics for Sore Throat - Doctor's Guide, 11/8/05
• Inappropriate Prescribing Of Antibiotics By Nurses And Doctors Continues - Science Daily, 10/6/05
• Gaining Ground In The Race Against Antibiotic Resistance - Science Daily, 9/22/05
• Use of Antibiotics for Acne May Increase Risk of Common Illness - Doctor's Guide, 9/21/05
• Recent Use Of Antibiotics Doubles Your Chances Of Being Resistant - Science Daily, 7/20/05
• FDA Approves Tygacil (Tigecycline), First-In-Class Antibiotic - Doctor's Guide, 6/16/05
• Pfizer's Single-Dose Antibiotic Zmax (Azithromycin Extended Release) Receives FDA Approval - Doctor's Guide, 6/13/05
• Researchers Make Gains In Understanding Antibiotic Resistance - Science Daily, 4/27/05
• Antibiotics Gain Strength With Natural Compound - Science Daily, 7/21/04
• Antibiotic-Resistant Infection Spreading - WebMD, 4/20/04
• FDA Approves Cefixime Suspension; Product to be Relaunched Under Suprax Brand - Doctor's Guide, 2/25/04
• Antibiotics Linked to Breast Cancer - WebMD, 2/18/04
• FAQ: Antibiotics and Breast Cancer - WebMD, 2/17/04
• Physicians Still Contributing to Antibiotic Resistance by Inappropriate Prescription Practices - Doctor's Guide, 10/20/03
• Antibiotic Resistance in Healthy Adults - WebMD, 10/9/03
• Early Antibiotics Tied to Asthma, Allergy - WebMD, 9/30/03
• Clarithromycin Appears To Defeat Bacterial Infections In Wheezing Children - Doctor's Guide, 9/24/03
• Voriconazole Clears Aspergillosis Infections With Less Overall Expense than Amphotericin - Doctor's Guide, 9/24/03
• Tigecycline Effective for Complicated Infections in Hospitalized Patients - Doctor's Guide, 9/22/03
• "Hidden" Clindamycin Resistance in Erythromycin-Resistant Staphylococci - Doctor's Guide, 9/19/03
• FDA Approves Cubicin (Daptomycin), First In New Class Of Antibiotics - Doctor's Guide, 9/15/03
• Fluoroquinolone Resistance 'Rampant' in Nursing Homes - Doctor's Guide, 9/15/03
• Linezolid Better Tolerated, As Effective As Vancomycin In Treating Resistant Gram-positive Paediatric Infections - Doctor's Guide, 8/27/03
• Azithromycin, but not Tetracycline, Effective Treatment for Mycoplasma Genitalium Infection - Doctor's Guide, 8/19/03
• Linezolid Effective Against Multiple Species of Anaerobes - Doctor's Guide, 8/4/03
• Linezolid May Be Useful Alternative For Treating Resistant Gram-Positive Bacteria - Doctor's Guide, 7/30/03
• Overview of Antibiotic Resistance in Staphylococcus Aureus - Doctor's Guide, 7/24/03
• Azithromycin Associated with Acute Delirium in two Elderly People - Doctor's Guide, 7/22/03
• Study Indicates Vancomycin Overuse - Doctor's Guide, 6/11/03
• Antibacterial Products Don't Cut Germs - WebMD, 5/21/03
• Similar Cure Rates With Ertapenem Or Piperacillin-Tazobactam For Surgical Infections With Or Without Enterococcus - Doctor's Guide, 4/29/03
• Olympics Offer Model for Cutting Antibiotic Use - Doctor's Guide, 4/8/03
• Overuse of Potent Antibiotics Now a Growing Problem - WebMD, 3/31/03
• Common Drug-Resistant Bacteria Spreading - WebMD, 3/10/03
• Sharp Jump Seen For Drug-Resistant Germs - Intelihealth, 3/10/03
• FDA Gives Approvable Letter For Ketek (Telithromycin) Tablets For Treatment Of Community-Acquired Respiratory Tract Infections - Doctor's Guide, 1/27/03
• Inappropriate Antibiotic Use Still Common In Children In United States - Doctor's Guide, 12/4/02
• Nosocomial Pneumonia Indication Approved For Levaquin (Levofloxacin) - Doctor's Guide, 11/5/02
• Antibacterial Soap a Wash - WebMD, 10/24/02
• Antibiotics May Help Your Arteries - WebMD, 10/14/02
• Antibiotic resistance on the rise - USA Today, 9/29/02
• Glaxosmithkline Receives FDA Approval For Augmentin XR (Amoxicillin/Clavulanate Potassium) Extended Release Tablets - Doctor's Guide, 9/26/02
• Antibiotics Aid Heart Patients - WebMD, 8/19/02 - "A year later, those who received an antibiotic were 36% less likely to be rehospitalized for a heart attack or chest pain than those who took a placebo ... The question, Mendall says, is whether the antibiotics are working by fighting infection or inflammation in these patients"
• Topical Antibiotics Reduce Postoperative Infections In Staphylococcus aureus Carriers - Doctor's Guide, 6/13/02
• CyDex, Inc. Announces First U.S. Approval of a Captisol-Enabled Medication - Doctor's Guide, 6/10/02
• First Novel Antifungal Agent In 40 Years, Cancidas*, Is Merck's Latest Discovery - Doctor's Guide, 6/5/02
• FDA Approves Pfizer Antifungal Medicine Vfend (Voriconazole) - Doctor's Guide, 5/28/02
• Telithromycin Effective Against Community-Acquired Pneumonia - Doctor's Guide, 5/16/02
• Safety-Net Antibiotics for Ear Infections - WebMD, 5/8/02
• Recent Antibiotic Use A Risk Factor For Trimethoprim-Sulfamethoxazole Resistance - Doctor's Guide, 5/6/02
• Ketek Shown To Be More Active Than Commonly Used Antibiotics In Children With Community-Acquired Respiratory Tract Infections - Doctor's Guide, 4/30/02
• Once Daily Ketek As Safe And Effective As Levofloxacin Three Times Daily In Treating Patients With Community Acquired Pneumonia (Cap) - Doctor's Guide, 4/29/02
• Ketek Shown To Be More Active Than Commonly Used Antibiotics In Children With Community-Acquired Respiratory Tract Infections - Doctor's Guide, 4/29/02
• Headaches-Germ Link Suggested - Intelihealth, 4/29/02 - "about 18 percent of chronic migraine sufferers were infected with the stomach bug helicobacter pylori and antibiotics appeared to clear the headaches ... Adding the friendly bacteria Lactobacillus seemed to work even better ... Helicobacter pylori, the bug that causes gut ulcers, has recently been linked to a growing list of diseases, including heart disease, autoimmune diseases and skin conditions"
• Ketek (Telithromycin) Shows Activity in Acute Maxillary Sinusitis Caused By Drug Resistant Bacteria - Doctor's Guide, 3/5/02
• Azithromycin Proves Safe and Better Tolerated than Other Antibacterials in Children - Doctor's Guide, 1/25/02
• Zithromax Receives FDA Approval as Single-Dose Treatment for Pediatric Ear Infections - Doctor's Guide, 12/18/01
• Vancomycin/Synercid Combination More Active Than Vancomycin Alone in Treating Resistant Staphylococcus Aureus Infections - Doctor's Guide, 12/17/01
• Ketek (Telithromycin) Active In Treating Community-Acquired Pneumonia Caused By Streptococcus Pneumoniae - Doctor's Guide, 12/17/01
• Bacteria More Resistant to Newer Therapy Than to Older Penicillin - Doctor's Guide, 12/17/01
• New Antibiotic, Quinupristin-Dalfopristin, For Severe Gram-Positive Infections - Doctor's Guide, 12/14/01
• First-Line Antibiotics Recommended for Uncomplicated Sinusitis - Doctor's Guide, 10/17/01
• Macrolide Resistance Doubles In Five Years - Doctor's Guide, 10/17/01
• Erythromycin Linked to Newborns' Intestinal Disorder - Doctor's Guide, 10/1/01
• FDA Approves New Cephalosporin Antibiotic, Spectracef (Cefditoren Pivoxil) - Doctor's Guide, 9/12/01
• Fewer Antibiotics For Kids Suggested - Intelihealth, 9/5/01
• Antibiotics May Help Heart Trouble - Intelihealth, 9/4/01
• New Blockbuster Antibiotics Beat Up on Bugs - WebMD, 7/25/01
• New Class Of Antibiotics Looks Good - Intelihealth, 7/25/01
• High-Dose, Short-Term Antibiotics May Help Curb Drug Resistance - Intelihealth, 7/3/01
• Antibiotics May Prevent Lyme Disease - WebMD, 6/12/01
• Treating Acne With Antibiotics Leads To Antibiotic Resistance - Doctor's Guide, 5/23/01
• Health Focus: Are Antibiotics Really Necessary For Ear Infections? - Intelihealth, 5/9/01 - "patients may be served just as well by giving them eardrops for pain and letting the infection heal itself"
• FDA Committee OKs Antibiotic - Intelihealth, 4/27/01 - "group was worried about ``silent toxicity'' if the drug interacted with other products, potentially causing an increase in liver enzymes and also possibly a prolongation of the heartbeat"
• FDA Panel Limits Recommendation of New Antibiotic, Advisers Stop Short of Saying Ketek Works Against Drug Resistance - WebMD, 4/26/01
• Missing Intestinal Bacterium Linked To Kidney Stones In CF Patients - Doctor's Guide, 9/25/98 - "The study is one of the first to directly link an absence of the organism, known as Oxalobacter formigenes, to the formation of the painful crystals ... O. formigenes appears to break down calcium oxalate before it can form crystals that evolve into kidney stones ... Peck and colleagues suspect prolonged antibiotic use and other high-dose drug regimens may preclude natural colonisation with the organism, or may irreversibly destroy the colonies"