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Home > Anti-aging Research > Splenda

Splenda/sucralose

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News & Research:

  • Open Access Article on Biological Effects of the Popular Artificial Sweetener Sucralose - Science Daily, 12/12/13 - "Some of the biological effects of sucralose described by Schiffman and Rother include: alterations in insulin, blood glucose, and glucagon-like peptide 1 (GLP-1) levels, metabolism of sucralose in the gastrointestinal tract to metabolites whose identity and safety profile are unknown, induction of cyctochrome P450 and P-glycoprotein in the gastrointestinal tract to levels that may limit the bioavailability of therapeutic drugs, reduction in the number and balance of beneficial bacteria in the gastrointestinal tract, histopathological findings in gastrointestinal tract including lymphocytic infiltrates into epithelium, epithelial scarring, mild depletion of goblet cells and glandular disorganization in the colon, decomposition and generation of chloropropanols (a potentially toxic class of compounds) during baking, and mutagenic alterations using several types of biological assays"
  • Artificial sweeteners may do more than sweeten: It can affect how the body reacts to glucose - Science Daily, 5/29/13 - "Our results indicate that this artificial sweetener is not inert -- it does have an effect ... we need to do more studies to determine whether this observation means long-term use could be harmful ... gave subjects either water or sucralose to drink before they consumed a glucose challenge test ... When study participants drank sucralose, their blood sugar peaked at a higher level than when they drank only water before consuming glucose ... Insulin levels also rose about 20 percent higher ... when people routinely secrete more insulin, they can become resistant to its effects, a path that leads to type 2 diabetes"
  • Are Artificial Sweeteners Safe? - WebMD, 3/25/05
  • Beware of More Deceptive Splenda Propaganda - mercola.com, 3/16/05
  • Sweetener in the Spotlight: Is Splenda Safe? - WebMD, 2/16/05 - "there are currently only a handful of studies that question Splenda's safety and more than 100 which attest to it's safe use ... it simply hasn't been around long enough to amass any long-term data -- or even short-term data involving heavy consumption"
  • Consumer Group Questions Splenda's Claims - mercola.com, 1/17/05
  • The skinny on sweeteners - MSNBC, 1/1/04 - "Based on what sweeteners are available now, my choice is Splenda, or sucralose, when used by itself" - See Splendaicon at drugstore.com.
  • The Potential Dangers of Sucralose - Dr. Mercola, 12/3/00
  • The Truth on Artificial Sweeteners - WebMD
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