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Recent Longevity News for the week ending 6/28/17

Drinking makes you older at the cellular level - Science Daily, 6/26/17 - "alcoholic patients had shortened telomere lengths, placing them at greater risk for age-related illnesses, such as cardiovascular disease, diabetes, cancer and dementia"

Extra-virgin olive oil preserves memory, protects brain against Alzheimer's - Science Daily, 6/21/17 - "consumption of extra-virgin olive oil protects memory and learning ability and reduces the formation of amyloid-beta plaques and neurofibrillary tangles in the brain -- classic markers of Alzheimer's disease ... at age 9 months and 12 months, mice on the extra virgin olive oil-enriched diet performed significantly better on tests designed to evaluate working memory, spatial memory, and learning abilities ... Studies of brain tissue from both groups of mice revealed dramatic differences in nerve cell appearance and function"

Grape-based compounds kill colon cancer stem cells in mice - Science Daily, 6/19/17 - "The combination of resveratrol and grape seed extract is very effective at killing colon cancer cells ... The incidence of tumors was suppressed in the mice consuming the grape compounds alone by 50 percent, similar to the rate in the group consuming the diet with sulindac" - See Best Naturals Grape Seed Extract 400 mg Veggie Capsule, 120 Count and Reserveage Nutrition - Resveratrol with Pterostilbene 500mg, Cellular Age-Defying Formula, 60 veg capsules at Amazon.com.

Veterans increasingly filing disability claims due to MRE exposure - duffelblog.com, 3/21/17 - “There honestly wasn’t a day that went by where I didn’t eat at least one — even at home,” he said, noting that he now averages just one bowel movement per month. “This [lack of] shit isn’t funny anymore.” - Note:  This article showed up on the militarytimes.com feed on Facebook.

Abstracts from this week:

Citrulline decreases hepatic endotoxin-induced injury in fructose-induced non-alcoholic liver disease: an ex vivo study in the isolated perfused rat liver - Br J Nutr. 2017 Jun 22:1-8 - "In vivo, citrulline significantly decreased dyslipidaemia induced by a high-fructose diet and insulin resistance. In the isolated perfused rat livers, endotoxaemia resulted in higher cytolysis (alanine aminotransferase release) and higher inflammation (Toll-like receptor 4) in livers of fructose-fed rats, and it was prevented by citrulline supplementation ... In this context of mild steatosis, our results suggest that fructose-induced NAFLD leads to an increased hepatic sensitivity to LPS-induced inflammation. Citrulline-induced restriction of the inflammatory process may thus contribute to the prevention of NAFLD" - See BulkSupplements Pure L-Citrulline Powder.

Sauna Bathing and Incident Hypertension: A Prospective Cohort Study - Am J Hypertens. 2017 Jun 13 - "In Cox regression analysis adjusted for baseline age, smoking, body mass index, and SBP; compared to participants reporting 1 sauna session per week, the hazard ratio for incident hypertension in participants reporting 2 to 3 sessions and 4 to 7 sessions was 0.76 (95% confidence interval: 0.57-1.02) and 0.54 (0.32-0.91), respectively" - See Crystal Saunas at Amazon.com.

  • Frequent sauna bathing protects men against dementia - Science Daily, 12/16/16 - "the study participants were divided into three groups: those taking a sauna once a week, those taking a sauna 2-3 times a week, and those taking a sauna 4-7 times a week ... The more frequently saunas were taken, the lower was the risk of dementia. Among those taking a sauna 4-7 times a week, the risk of any form of dementia was 66% lower and the risk of Alzheimer's disease 65% lower than among those taking a sauna just once a week ... Previous results from the KIHD study have shown that frequent sauna bathing also significantly reduces the risk of sudden cardiac death, the risk of death due to coronary artery disease and other cardiac events, as well as overall mortality" - See JNH Lifestyle saunas at Amazon.com.

Curcuminoids modify lipid profile in type 2 diabetes mellitus: A randomized controlled trial - Complementary Therapies in Medicine, Aug 2017 - "In this 12-week randomized double-blind placebo-controlled trial, subjects with T2D (n = 118) were assigned to curcuminoids (1000 mg/day plus piperine 10 mg/day) or placebo plus standard of care for T2D ... Between-group comparison of change in the study parameters revealed significant reductions in serum levels of TC (−21.86 ± 25.78 versus −17.06 ± 41.51, respectively; p = 0.023), non-HDL-C (−23.42 ± 25.13 versus −16.84 ± 41.42, respectively; p = 0.014) and Lp(a) (−1.50 ± 1.61 versus −0.34 ± 1.73, respectively; p = 0.001) and elevations in serum HDL-C levels (1.56 ± 4.25 versus −0.22 ± 4.62, respectively; p = 0.048) in the curcuminoids group as compared with the placebo group (p < 0.05)" - [Nutra USA] - See curcumin products at Amazon.com and piperine extract at Amazon.com.

International Society of Sports Nutrition Position Stand: protein and exercise - Journal of the International Society of Sports Nutrition, Jun 3, 2017 - "muscle protein synthesis (MPS) ... Acute protein doses should strive to contain 700–3000 mg of leucine and/or a higher relative leucine content, in addition to a balanced array of the essential amino acids (EAAs) ... Rapidly digested proteins that contain high proportions of essential amino acids (EAAs) and adequate leucine, are most effective in stimulating MPS" - [Nutra USA] - See BulkSupplements Pure L-Leucine Powder (1 Kilogram).

Impact of Vitamin D deficiency on subclinical carotid atherosclerosis: a pooled analysis of cohort studies - J Clin Endocrinol Metab. 2017 May 9 - "Both Vitamin D deficiency and Vitamin D insufficiency are associated with subclinical atherosclerosis, potentially suggesting an increased CV risk in these clinical settings" - See vitamin D at Amazon.com.

Impact of phenolic-rich olive leaf extract on blood pressure, plasma lipids and inflammatory markers: a randomised controlled trial - Eur J Nutr. 2017 Jun;56(4):1421-1432 - "A total of 60 pre-hypertensive [systolic blood pressure (SBP): 121-140 mmHg; diastolic blood pressure (DBP): 81-90 mmHg] males [mean age 45 (±SD 12.7 years, BMI 26.7 (±3.21) kg/m2] consumed either OLE (136 mg oleuropein; 6 mg hydroxytyrosol) or a polyphenol-free control daily for 6 weeks before switching to the alternate arm after a 4-week washout ... Daytime [-3.95 (±SD 11.48) mmHg, p = 0.027] and 24-h SBP [-3.33 (±SD 10.81) mmHg, p = 0.045] and daytime and 24-h DBP [-3.00 (±SD 8.54) mmHg, p = 0.025; -2.42 (±SD 7.61) mmHg, p = 0.039] were all significantly lower following OLE intake, relative to the control. Reductions in plasma total cholesterol [-0.32 (±SD 0.70) mmol/L, p = 0.002], LDL cholesterol [-0.19 (±SD 0.56) mmol/L, p = 0.017] and triglycerides [-0.18 (±SD 0.48), p = 0.008] were also induced by OLE compared to control, whilst a reduction in interleukin-8 [-0.63 (±SD 1.13) pg/ml; p = 0.026] was also detected" - [Nutra USA] - See Olive leaf extract at Amazon.com.

Neat Tech Stuff / "How To's":

3 cheap fixes for your TV's awful speakers - CNET, 6/20/17 - Here's my solution: TaoTronics Wireless Portable Bluetooth Transmitter Connected to 3.5mm Audio Devices, Paired with Bluetooth Receiver, TV Ears, Bluetooth Dongle, A2DP Stereo Music Transmission and Bose SoundLink Mini Bluetooth Speaker II.  Plus you put the speaker at the head of the bed so that you're not cranking up the sound at the other end of the room and waking up other people in the house.

Get notified of Amazon price drops - CNET, 6/19/17 - "If you're a Chrome user, try installing Honey. Originally just a coupon-code lookup tool, the service now offers an Amazon-specific price tracker called DropList"

Health Focus (Telomeres):