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Home > Health Conditions > Skin Care

Skin Care

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  • Successful Treatment of Bullous Pemphigoid Lesions by Berberine Stamp Therapy: A Case Report and Literature Review - Front Med (Lausanne) 2022 Jul 1 - "Bullous pemphigoid (BP) is a life-threatening autoimmune disease of the skin that is mainly characterized by a large range of tension blisters and intense itching of the skin. The 1-year mortality rate of BP was 23.5%. Superinfection caused by skin lesion ulceration is one of the important causes of disease death. Therefore, it is challenging to control infection and improve skin wound healing. Here, we report the case of an elderly woman who presented with BP and involved the oral mucosa. The patient was successfully treated with hormones combined with topical berberine, and 95% of the patients' lesions healed completely after 1 month. In addition, we inductively analyzed the current treatments for BP to provide a reference for BP clinical treatment" - See berberine at Amazon.com.
  • Skin dryness induced in the KK-Ay/TaJcl type 2 diabetes mouse model deteriorates following dapagliflozin administration - Biol Pharm Bull 2022 May 17 - "SGLT-2 inhibitors cause skin dryness ... Dapagliflozin treatment decreased collagen type I and hyaluronic acid levels in mice; additionally, it affected the TGF-β/hyaluronan synthase pathway, further reducing hyaluronic acid levels. The results indicate that the reduction in hyaluronic acid levels plays an important role in the occurrence of dry skin in diabetes" - See collagen supplements at Amazon.com and hyaluronic acid at Amazon.com.
  • The impact of vitamin D supplementation as an adjuvant therapy on clinical outcomes in patients with severe atopic dermatitis: A randomized controlled trial - Pharmacol Res Perspect 2020 Dec - "Vitamin D supplementation with standard treatment yielded positive clinical outcomes in mild and moderate atopic dermatitis; however, the potential benefit of vitamin D in severe cases remains unclear ... The patients were randomized to receive either vitamin D 3 1600 IU/day or placebo, plus baseline therapy of topical 1% hydrocortisone cream twice daily for 12 weeks. The primary endpoints were the change in mean Eczema Area and Severity Index (EASI) score at the end of the study and the mean percent change in EASI score from baseline to week 12. Eighty-six subjects completed the study. The treated group achieved a significant higher level of 25 hydroxy vitamin D (P < .001) compared to control group at week 12. The mean EASI score was significantly lower in the treatment group compared to placebo group (P = .035). The percent change in EASI score from baseline differed significantly between the supplementation (56.44 ± 29.33) and placebo (42.09 ± 19.22) groups after intervention (P = .039). Vitamin D supplementation could be an effective adjuvant treatment that improves the clinical outcomes in severe atopic dermatitis" - [Nutra USA] - See vitamin D at Amazon.com and vitamin D at iHerb.
  • Effect of the Lactococcus Lactis 11/19-B1 Strain on Atopic Dermatitis in a Clinical Test and Mouse Model - Nutrients. 2020 Mar 14 - "Some lactic acid bacteria (LAB) are known to improve atopic dermatitis (AD) through the regulation and stimulation of the host immune system. In this study, we found that ingestion of yogurt containing Lactococcus lactis 11/19-B1 strain (L. lactis 11/19-B1) daily for 8 weeks significantly improved the severity scoring of atopic dermatitis (SCORAD) system score from 38.8 ± 14.4 to 24.2 ± 12.0 in children suffering from AD ... AD-like skin lesions on the dorsal skin and ear were most improved by L. lactis 11/19-B1 intake among the five LAB species. In addition, analysis of CD4+ T cell subsets in Peyer's patches (PPs) and cervical lymph nodes (CLNs) indicated that the intake of L. lactis 11/19-B1 generally suppressed all subsets related to inflammation, i.e., Th1, Th2 and Th17, instead of activating the suppressive system, Treg, in the AD mouse model. Histological observations showed ingestion of L. lactis 11/19-B1 significantly suppressed severe inflammatory findings, such as inflammatory cell filtration, epidermal erosion and eosinophil infiltration. These results suggest that the immunomodulatory effects of L. lactis 11/19-B1 contribute to improvements in AD pathology" - [Nutra USA]
  • Skincare 101: The only products you need to get good skin - CNET, 1/1/20 - "According to dermatologist Amie Sessa, you should use a gentle cleanser and avoid using too-hot water (which can be harsh on your face). Campbell's favorite cleansers are Cetaphil Gentle, CeraVe Hydrating or Skinceuticals Gentle Cleanser ... Once you cleanse, you can immediately follow with a moisturizer, or add an antioxidant serum before you moisturize if you'd like. "Antioxidants should be used during the day, as this is when you are most exposed to sun and pollution. They cause reactive oxygen species (i.e., free radicals) that break down collagen and elastin (the building blocks of the skin) and mutate DNA leading to sagging, dull and pigmented skin," Campbell says ... For dry or combination skin types she recommends a moisturizing serum with Vitamin C and ferulic acid, and for oily skin, an antioxidant serum that is lightweight or oil-free if you're prone to breakouts. If you want to add an extra boost of hydration, hyaluronic acid is a great option for layering under a moisturizer and works for most skin types. It also layers well with other products and is gentle."
  • Benefits of Hesperidin for Cutaneous Functions - Evid Based Complement Alternat Med. 2019 Apr 2;2019:2676307 - "Hesperidin is a bioflavonoid, with high concentration in citrus fruits. In addition to its well-known benefits for cardiovascular function, type II diabetes, and anti-inflammation, recent studies have demonstrated multiple benefits of hesperidin for cutaneous functions, including wound healing, UV protection, anti-inflammation, antimicrobial, antiskin cancer, and skin lightening. In addition, hesperidin enhances epidermal permeability barrier homeostasis in both normal young and aged skin. The mechanisms by which hesperidin benefits cutaneous functions are attributable to its antioxidant properties, inhibition of MAPK-dependent signaling pathways, and stimulation of epidermal proliferation, differentiation, and lipid production. Because of its low cost, wide availability, and superior safety, hesperidin could prove useful for the management of a variety of cutaneous conditions" - See hesperidin at Amazon.com.
  • You might be able to fight dry winter skin with these three nutrition hacks - Washington Post, 1/23/19 - "Staying well hydrated helps keep all of our bodily systems functioning smoothly, so at a minimum, you should aim for the recommended daily intake of 91 ounces of liquid for women and 125 ounces for men, amounts which include not only water, but all nonalcoholic liquids consumed ... Since most of us get plenty of omega-6, it’s a smart strategy to focus on upping our intake of omega-3 ... Two nutrients bountiful in richly hued fruit and vegetables which researchers have begun to home in on are carotenoids (including beta-carotene, a form of vitamin A, lutein, zeaxanthin and others) and vitamin C. They act as antioxidants, protecting cells from damage, and they are essential for the skin’s growth and repair. "
  • Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence - Phytother Res. 2016 May 23 - "Overall, there is early evidence that turmeric/curcumin products and supplements, both oral and topical, may provide therapeutic benefits for skin health" - See curcumin products at Amazon.com.
  • Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology - J Med Food. 2015 Dec;18(12):1340-8 - "specific bioactive collagen peptides (BCP) on the cellulite treatment of normal and overweight women. In total, 105 women aged 24-50 years with moderate cellulite ... 105 women aged 24-50 years with moderate cellulite were randomized to orally receive a daily dosage of 2.5 g BCP or a placebo over 6 months ... The results of the study demonstrated that a regular ingestion of BCP over a period of 6 months led to a clear improvement of the skin appearance in women suffering from moderate cellulite. Based on the current data, it can be concluded that a long-term therapy with orally administered BCP leads to an improvement of cellulite and has a positive impact on skin health" - [Nutra USA] - Here's what I take: Peptan® Hydrolyzed Collagen Protein Powder - For Hair - Nails - Joint Pain Relief - Skin Care - Appetite Suppressant - Building Muscle - Bone Density - Osteopenia at Amazon.com.
  • Influence of Topical, Systemic and Combined Application of Antioxidants on the Barrier Properties of the Human Skin - Skin Pharmacol Physiol. 2016 Jan 23 - "The formation of free radicals in human skin by solar ultraviolet radiation is considered to be the main reason for extrinsic skin aging. The antioxidants in human tissue represent an efficient protection system against the destructive action of these reactive free radicals ... The study included 5 groups of 15 volunteers each, who were treated for 2 months with antioxidant-containing or placebo tablets, creams or a combination of antioxidant-containing tablets and cream ... The verum cream had a positive influence on epidermal thickness, elasticity and skin moisture, but the verum tablets improved the epidermal thickness only. The combined application of verum tablets and creams led to a significant improvement of all investigated skin parameters, whereas the application of placebo tablets or cream did not influence any parameters" - See OZ Naturals- THE BEST Vitamin C Serum For Your Face Contains Clinical Strength 20% Vitamin C + Hyaluronic Acid Anti Wrinkle Anti Aging Serum For A Radiant & More Youthful Glow!, Protein Essentials Hydrolyzed Collagen Protein Powder with Peptan® (16oz) at Amazon.com and Sunkist Grower Select Blueberry Capsules, 500 mg, 90 Count Bottle.
  • French Maritime Pine Bark Extract (Pycnogenol®) Effects on Human Skin: Clinical and Molecular Evidence - Skin Pharmacol Physiol. 2015 Oct 23 - "the existing data provide compelling evidence that Pycnogenol® intake does not only provide photoprotection, but may be used to (i) reduce hyperpigmentation of human skin and (ii) improve skin barrier function and extracellular matrix homeostasis" - See Pycnogenol at Amazon.com.
  • The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials - J Cosmet Dermatol. 2015 Sep 12 - "Skin dryness and an accelerated fragmentation of the collagen network in the dermis are hallmarks of skin aging. Nutrition is a key factor influencing skin health and consequently its appearance. A wide range of dietary supplements is offered to improve skin health. Collagen peptides are used as a bioactive ingredient in nutricosmetic products and have been shown in preclinical studies to improve skin barrier function, to induce the synthesis of collagen and hyaluronic acid, and to promote fibroblast growth and migration ... Oral collagen peptide supplementation significantly increased skin hydration after 8 weeks of intake. The collagen density in the dermis significantly increased and the fragmentation of the dermal collagen network significantly decreased already after 4 weeks of supplementation. Both effects persisted after 12 weeks. Ex vivo experiments demonstrated that collagen peptides induce collagen as well as glycosaminoglycan production, offering a mechanistic explanation for the observed clinical effects" - [Nutra USA] - See Protein Essentials Hydrolyzed Collagen Protein Powder with Peptan® (16oz) at Amazon.com. It's the Rousselot Peptan collagen brand talked about in the Nutra USA article.  See the Rousselot Peptan collagen website.
  • Fruit, Vegetable and Dietary Carotenoid Intakes Explain Variation in Skin-Color in Young Caucasian Women: A Cross-Sectional Study - Nutrients. 2015 Jul 15 - "Fruit and vegetables contain carotenoid pigments, which accumulate in human skin, contributing to its yellowness. This effect has a beneficial impact on appearance ... Higher combined fruit and vegetable intakes (β = 0.8, p = 0.017) were associated with higher overall skin yellowness values. Higher fruit combined fruit and vegetable intakes (β = 1.0, p = 0.004) were associated with increased unexposed skin yellowness. Combined fruit and vegetables plus dietary carotenoid intakes contribute to skin yellowness in young Caucasian women. Evaluation of interventions using improvements in appearance as an incentive for increasing fruit and vegetable consumption in young women is warranted"
  • Lifestyle and Youthful Looks - Medscape, 7/7/14 - "In Dutch men, smoking, having skin that went red in the sun, being outside in the sun most of the summer, sunbed use, wearing false teeth and not flossing teeth were all significantly associated (P < 0·05) with a total 9.3-year higher perceived facial age in a multivariate model adjusting for chronological age. In Dutch women, smoking, sunbathing, sunbed use, few remaining teeth and a low body mass index (BMI) were associated with a total 10.9-year higher perceived facial age. In English women, cleaning teeth only once a day, wearing false teeth, irregular skin moisturization and having skin that went red in the sun were associated with a total 9.1-year higher perceived facial age. Smoking and sunbed use were associated more strongly with wrinkling in women than in men. BMI, sun exposure and skincare were associated predominantly with perceived facial age via wrinkling, whereas oral care was associated via other facial features"
  • Eat your fruits, vegetables for skin with sun-kissed glow - Science Daily, 8/27/14 - "Skin coloration can arise as a result of two distinct processes," explain the team leading the research: through tanning (melanisation) or the assimilation of fruit and vegetables (carotenoid ingestion) ... Results from both studies showed a clear preference for strong color values; 86% of the attendants to the first study voted for the high carotenoid version, while 78.5% of the participants to the second one opted for the high melanin variant ... in a third and final study, the team pitched 24 high carotenoid and high melanin faces against each other, asking attendants to choose the one deemed more appealing; results showed a 75.9% preference for carotenoid coloring over the melanin one" - See carotenoids at Amazon.com.
  • Top 4 Foods for Thicker, Shinier Hair - ABC News, 4/29/14 - "Yogurt ... These good bacteria help balance the community of microorganisms that live in our intestines. And a recent study by MIT researchers suggests that probiotics help produce that “healthy glow” we all want, by making skin more radiant and hair more shiny, thick, and lustrous ... The researchers suggest that probiotics decrease inflammation in the top layers of the skin leading to healthier skin and hair ... Vitamin D is essential for keeping your hair growing strong and preventing breakage—it helps keep the follicles healthy, through the growth, shedding, and regrowth of new hairs ... Zinc is a powerful nutrient for hair growth—it helps accelerate the repair of damaged hair follicles, which keeps your hair healthy through all of its growth phases. Zinc deficiency is also associated with hair loss ... The brassicas (cabbage, Brussels sprouts, broccoli, kale) are packed full of healthy nutrients and have been shown to help decrease the risk of heart disease and cancer. They are also rich in phosphatidic acid, little fatty acid messengers involved in cell creation and survival. A study in the Journal of Investigative Dermatology found that phosphatidic acid also promotes hair growth due to its growth-promoting effects on the cells in our hair follicles"
  • Younger Skin Through Exercise - NYTimes.com, 4/16/14 - "The scientists biopsied skin samples from each volunteer and examined them microscopically. When compared strictly by age, the skin samples overall aligned with what would be expected. Older volunteers generally had thicker outer layers of skin and significantly thinner inner layers ... But those results shifted noticeably when the researchers further subdivided their samples by exercise habits. They found that after age 40, the men and women who exercised frequently had markedly thinner, healthier stratum corneums and thicker dermis layers in their skin. Their skin was much closer in composition to that of the 20- and 30-year-olds than to that of others of their age, even if they were past age 65 ... the researchers next set a group of sedentary volunteers to exercising ... I don’t want to over-hype the results, but, really, it was pretty remarkable to see ... Under a microscope, the volunteers’ skin “looked like that of a much younger person, and all that they had done differently was exercise"
  • New Treatments For Blotchy Skin - ABC News, 3/24/14 - "Niacinimide ... This is an ingredient used in some “cosmeceuticals,” particularly in moisturizers. Halder says it prevents small melanin particles (what turns your skin brown) from moving from the bottom layer to the top layer of the skin. It is a form of vitamin B3 that blocks the pigment pockets from moving to the skin’s surface ... Ellagic Acid ... The name sounds scary, but it is actually derived from strawberries, cherries and pomegranates" - Note:  It seems like you could raise the good cholesterol at the same time by taking niacin:
    • What Is the Difference Between Niacin & Niacinamide? - LiveStrong.com - "Your body can convert niacin into niacinamide ... Niacin and niacinamide have identical function when used as vitamins ... their pharmacologic properties differ. For example, high doses of niacin can cause skin flushing. Niacinamide, however, does not have the same vasodialating, or blood-vessel widening, effects, that niacin has, so it does not lead to skin flushing" - Note:  You'll find contradictory information on the Internet but niacinamide will not raise HDL and niacin will.  See niacin at Amazon.com.
  • Foods that help save your skin - The Washington Post, 2/26/14 - "Antioxidants ... Omega 3 fatty acids ... Vitamin A ... Zinc ... Water ... probiotic supplement in the diet to help restore good bacteria to the digestive tract ... skin enemies ... Sugary foods ... Processed fats and oils such as trans fats, corn oil, vegetable oil and canola oil"
  • Gamma-Linolenic Acid Levels Correlate with Clinical Efficacy of Evening Primrose Oil in Patients with Atopic Dermatitis - Adv Ther. 2014 Jan 17 - "Atopic dermatitis (AD) has been related to a deficiency of delta-6-desaturase, an enzyme responsible for the conversion of linoleic acid to gamma-linolenic acid (GLA). Evening primrose oil (EPO) contains high amounts of GLA. Therefore, this study investigated whether EPO supplementation results in an increase in plasma GLA and its metabolite dihomo-gamma-linolenic acid (DGLA) correlating with clinical improvement of AD, assessed by the SCORing Atopic Dermatitis (SCORAD) index ... The clinical disease activity under EPO treatment correlates with the individual increase in plasma GLA levels. Thus, the results of this pilot study indicate that an increase in plasma GLA might be used as predictive parameter for responsiveness of AD to EPO therapy" - See evening primrose oil at Amazon.com.
  • The best foods for clear skin - washingtonpost.com, 9/18/13 - "Stay away from anything that comes in a box ... both because of the added sugars and because of other additives ... gobble up produce of all colors, plus nuts and seeds, to get minerals, fiber and vitamins A, C and E ... Foods that keep your blood sugar low are also good for the skin ... avoid sugar ... omega-3 fatty acids, which are found in wild salmon, help support healthy cell membranes ... Another smart move is the addition into the diet of probiotics, which can be found in yogurt and kefir as well as nutritional supplements. (She prefers supplements over yogurt because they contain much higher amounts of probiotics.)" - See Garden of Life Primal Defense HSO Probiotic Formula at Amazon.com.
  • 5 Foods for Healthy Skin - ABC News, 9/12/13 - "Strawberries ... Olive oil ... Green tea ... Pumpkin ... Pomegranate"
  • Sleep deprivation linked to aging skin, study suggests - Science Daily, 7/23/13 - "Our study is the first to conclusively demonstrate that inadequate sleep is correlated with reduced skin health and accelerates skin aging. Sleep deprived women show signs of premature skin aging and a decrease in their skin's ability to recover after sun exposure ... The study involved 60 pre-menopausal women between the ages of 30 and 49, with half of participants falling into the poor quality sleep category ... Using the SCINEXA skin aging scoring system, poor quality sleepers showed increased signs of intrinsic skin aging including fine lines, uneven pigmentation and slackening of skin and reduced elasticity. In this system, a higher score means a more aged appearance. The average score in the good quality sleepers was 2.2 versus 4.4 in poor quality sleepers"
  • Lutein, Zeaxanthin, and Skin Health - Medscape, 6/7/13 - "Results from cell culture and animal studies showing that lutein and zeaxanthin exhibit positive skin health benefits have considerable merit and suggest an avenue by which these carotenoids may function. The results from one human study demonstrate that orally administered lutein and zeaxanthin can inhibit lipid peroxidation on the surface of the skin and help bolster the skin's photoprotective activity, potentially protecting the skin from exposure to light, particularly UV light. Since the typical diet of people in the United States is about 2 mg of lutein per day, due to the ingestion of foods such as green leafy vegetables that contain the highest levels of diet-derived lutein and zeaxanthin,[15] it may be considered advisable to increase the daily intake of lutein and zeaxanthin for optimal skin health and photoprotection" - See Jarrow Formulas, CarotenALL at Amazon.com.
  • 9 Best Foods for Your Skin - US News and World Report, 5/16/12 - "Tomatoes ... Mangoes, papaya, and apricots ... Cocoa powder ... Flaxseeds ... Sweet potatoes ... Mussels ... Spinach ... Canned tuna ... Safflower Oil" - Note:  I'm not buying the chocolate or safflower oil suggestions.
  • Do Fruits and Veggies Make You More Attractive? - WebMD, 3/7/12 - "changes in the redness and yellowness of skin in white people may be linked to the number of servings of fruit and vegetables they eat on a daily basis. These antioxidant-rich foods, which are loaded with plant-based pigments, seem to affect skin tone ... They suggest it's the carotenoids -- the red, yellow, and orange pigments in fruits and vegetables -- that play an important role in skin tone. Foods such as carrots, sweet potatoes, squash, and apricots are rich in beta-carotene, as are some dark green vegetables, including spinach and kale ... Another carotenoid is lycopene, which is found in tomatoes and pink grapefruits" - See Jarrow Formulas, CarotenALL at Amazon.com and Garden of Life, Radical Fruits Antioxidant Complex at Amazon.com.
  • Which Foods Can Help Your Skin Look Better - CBS Chicago, 7/14/11 - "Experts say that what you eat has a big effect on how you look ... people who switched to a hypoglycemic – or low sugar – diet for three months reduced their pimples by 20 percent ... So what should we eat to prevent or even get rid of wrinkles? ... What you want to do is build up the collagen and there’s certain collagen builders, such as Vitamin C and Vitamin E ... To avoid dry, flaky skin or eczema, increase your omega 3s ... There’s less scientific proof about cellulite, but many nutritionists also feel you can reduce the appearance of those unsightly bulges by eating dark red and purple foods, which help rid the body of toxins – things like cranberry juice, blueberries, cherries and radicchio lettuce ... If you’re looking for a cure-all for nearly any skin problem, it’s extra virgin olive oil. It helps reduce inflammation, and can help everything from psoriasis to eczema to acne .. dairy, even skim-milk, seems to make nearly every skin problem worse"
  • Eating vegetables gives skin a more healthy glow than the sun, study shows - Science Daily, 1/11/11 - "people who eat more portions of fruit and vegetables per day have a more golden skin colour, thanks to substances called carotenoids. Carotenoids are antioxidants that help soak up damaging compounds produced by the stresses and strains of everyday living, especially when the body is combating disease. Responsible for the red colouring in fruit and vegetables such as carrots and tomatoes, carotenoids are important for our immune and reproductive systems ... given the choice between skin colour caused by suntan and skin colour caused by carotenoids, people preferred the carotenoid skin colour" - See Jarrow Formulas, CarotenALL, Mixed Carotenoid Complex at Amazon.com.
  • Pomegranate compounds show skin health potential - Nutra USA, 8/10/10 - "ellagic acid may prevent the degradation of collagen in human skin cells, which would maintain skin structure and slow the formation of wrinkles ... Topical or dietary interventions with berries and pomegranate rich in ellagic acid and ellagitannins are promising strategies in curtailing skin wrinkling and cutaneous inflammation associated with chronic UV exposure leading to photoageing" - [Abstract] - See pomegranate at Amazon.com.
  • Dietary compound ellagic acid alleviates skin wrinkle and inflammation induced by UV-B irradiation - Exp Dermatol. 2010 Aug;19(8):e182-90 - "Ellagic acid, a polyphenol compound present in berries and pomegranate, has received attention as an agent that may have potential bioactivities preventing chronic diseases ... These results demonstrate that ellagic acid prevented collagen destruction and inflammatory responses caused by UV-B. Therefore, dietary and pharmacological interventions with berries rich in ellagic acid may be promising treatment strategies interrupting skin wrinkle and inflammation associated with chronic UV exposure leading to photoageing" - See pomegranate at Amazon.com.
  • Lack of omega-6 fatty acid linked to severe dermatitis - Science Daily, 4/14/10 - "Without arachidonic acid, the mice developed severe ulcerative dermatitis. The animals were very itchy, they scratched themselves continuously, and they developed a lot of bleeding sores" - Note:  I doubt if that's a problem in America where they get way to much omega-6 already.
  • New Role Of Vitamin C In Skin Protection; Relevance To The Cosmetics Industry - Science Daily, 9/8/09 - "a form of Vitamin C helped to promote wound healing and also helped protect the DNA damage of skin cells ... Previously, the group has published evidence that DNA repair is upregulated in people consuming vitamin C supplements ... The results demonstrated that vitamin C may improve wound healing by stimulating quiescent fibroblasts to divide and by promoting their migration into the wounded area. Vitamin C could also protect the skin by increasing the capacity of fibroblasts to repair potentially mutagenic DNA lesions ... Free radicals are associated with premature skin aging, and antioxidants, such as vitamin C, are known to counter these highly damaging compounds. This new evidence suggest that, in addition to ‘mopping up’ free radicals, vitamin C can help remove the DNA damage they form, if they get past the cell’s defences"
  • Better skin from the beauty aisle - MSNBC, 1/18/09 - Has a doctor's evaluation of various skin aging solutions.
  • LycoRed files patent for skin health science - Nutra USA, 11/7/08 - "According to LycoRed, subjects were supplemented by either Lyc-O-Mato capsules (10mg lycopene per day), or a placebo, for ten weeks. Following exposure to UV radiation at the end of the study, it was found that subjects in the tomato extract group had a sunburn cell count six times lower than in the placebo group. There was also evidence of reduced depletion of Langerhans cells, said the company" - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com.
  • Vitamin D may protect skin from within: Study - Nutra USA, 10/8/08 - "Atopic dermatitis (AD) ... All of the participants were given daily vitamin D supplements of 4000 IUs for 21 days ... After supplementation, the skin of people with AD showed statistically significant increases in cathelicidin from 3.53 to 23.91 relative copy units (RCU). Moreover, normal skin showed a “modest increase”, said the researchers, from 1.0 to 1.78 RCU" - See vitamin D at Amazon.com.
  • Flax and borage oil may boost skin health from within - 10/3/08 - "the researchers noted a significant decrease in reddening of the skin in the flaxseed and borage oil groups of 45 and 35 per cent, respectively, compared to baseline values. No differences were recorded in the placebo group ... blood flow to the in skin also decreased in the oil groups ... Measurements of water loss from the skin showed that the oil supplements were associated with decreases of about 10 per cent after six weeks, with only the flaxseed oil group showing further decreases at the end of 12 weeks (25 per cent) ... The roughness and scaling – dry peeling skin – was also decreased significantly after 12 weeks of flaxseed and borage oil supplementation, with no differences in the placebo group" - [Abstract]
  • What To Eat For Glowing Healthy Skin - Science Daily, 11/14/07 - "the antioxidants in vitamins C and E can protect the skin from sun damage and help reduce damage in skin cells caused by harmful free radicals, which contribute to aging skin. Similarly, we have long known that the B vitamin biotin is responsible for forming the basis of skin, hair and nail cells, and vitamin A – found in many fruits and vegetables – maintains and repairs skin tissue"
  • On The Cover: Scientifically Advanced Skin Care - Life Extension Magazine, 1/07
  • Eat Right To Keep Healthy Skin - CBS 2 Chicago, 4/30/05 - "Clinical studies have found that eating a diet rich in fruits, vegetables, whole grains, legumes and omega-3 fatty acids can help skin retain its healthy glow and look youthful ... foods for healthy skin include those rich in lycopene. That's a pigment that gives many fruits and vegetables their red color. It's a proven antioxidant, and antioxidants are important because they reduce the risk of several types of cancer and they prevent the formation of harmful byproducts of metabolism called free radicals"
  • Rub Away Aged Skin - Life Extension Magazine, 6/04
  • What do you recommend for thin, dry skin and hair and brittle nails? - Dr. Weil, 10/21/03
  • Rejuvenate Your Skin While You Sleep - Life Extension Magazine cover story, 8/03
  • Green Tea Gives Skin Healthy Glow - HealthDay, 5/15/03 - "Green tea contains compounds called polyphenols, which help eliminate free radicals. These free radicals can cause cancer by altering DNA. Polyphenols also protect healthy cells while promoting the death of cancer cells ... Cells that migrate toward the surface of the skin normally live about 28 days, and by day 20 they basically sit on the upper layer of the skin getting ready to die. But EGCG reactivates them ... EGCG may offer potential benefits for skin conditions including psoriasis, rosacea, wrinkles and wounds" - See iHerb green tea extracts.  My favorite is Jarrow green tea at iHerb.
  • GLA: The Right Remedy for Eczema? - Dr. Weil, 11/21/02 - "It has specific nourishing effects on skin, hair, and nails that are not duplicated by omega–3 fatty acids ... It is true that a high ratio of omega-6 to omega-3 fatty acids in the diet promotes inflammation by favoring synthesis of pro-inflammatory hormones (prostaglandins). But the amount of GLA needed to treat eczema and other skin conditions (500 milligrams twice a day) is too small to affect that ratio significantly" - See gamma linolenic acid at Amazon.com.
  • Increased Blood Antioxidants And Selenium Levels May Augur A Promising Therapy For Patients With Vitiligo - Doctor's Guide, 11/8/02
  • Link Found Between Vitamin E Intake and Immunoglobulin E In Treatment Of Atopic Dermatitis - Doctor's Guide, 5/31/02 - "Dietary vitamin E (VE) could be an excellent tool in treating atopic dermatitis"
  • Nutrition for the Skin - What You Should Know Before Undergoing a Surgical Procedure - Wellness Insider, 5/23/02 - "free radicals can accelerate the aging process of the skin, resulting in wrinkles and sunspots, not to mention an increased risk of skin cancer ... These antioxidants are important in protecting you from disease and can help shield you from skin cancer, maintain youthful, healthy skin, and even help to promote and expedite the healing process after a surgical procedure"
  • Few Vitamins Effectively Prevent or Reverse Skin Damage - Medscape, 3/02 - "Despite advertising claims, almost all available topical formulations contain very low concentrations of antioxidants that are not well absorbed by the skin ... There are 3 antioxidants that have been proven to decrease the effect of the sun on the skin and actually prevent further damage: selenium, vitamin E, and vitamin C ... Recent animal studies have found that when selenium is taken orally or through the skin in the form of L-selenomethionine, it provided protection against both everyday and excessive UV damage ... New laboratory studies suggest vitamin E helps inactivate free radicals, making them less likely to cause damage ... Even minimal UV exposure can decrease the vitamin C levels in the skin by 30%, while exposure from the ozone of city pollution can decrease the level by 55%"
  • Topical Vitamin C May Have Beneficial Effect On Photaged Skin - Doctor's Guide, 4/13/01 - "vitamin C levels of the skin can be severely depleted following UV irradiation ... By comparison with placebo controls, there was a highly significant increase in the skin microrelief density and a decrease of the deep furrows on the side of the neck treated with Vitamin C cream"

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