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Successful Treatment of
Bullous Pemphigoid Lesions by Berberine Stamp Therapy: A Case Report and
Literature Review - Front Med (Lausanne) 2022 Jul 1 -
"Bullous pemphigoid (BP) is a life-threatening
autoimmune disease of the skin that is mainly characterized by a large range of
tension blisters and intense itching of the skin. The 1-year mortality rate of
BP was 23.5%. Superinfection caused by skin lesion ulceration is one of the
important causes of disease death. Therefore, it is challenging to control
infection and improve skin wound healing. Here, we report the case of an elderly
woman who presented with BP and involved the oral mucosa. The patient was
successfully treated with hormones combined with topical berberine, and 95% of
the patients' lesions healed completely after 1 month. In addition, we
inductively analyzed the current treatments for BP to provide a reference for BP
clinical treatment" - See berberine at Amazon.com.
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Skin dryness induced in the
KK-Ay/TaJcl type 2 diabetes mouse model deteriorates following dapagliflozin
administration - Biol Pharm Bull 2022 May 17 -
"SGLT-2 inhibitors cause skin dryness ... Dapagliflozin treatment decreased
collagen type I and hyaluronic acid levels in mice; additionally, it affected
the TGF-β/hyaluronan synthase pathway, further reducing hyaluronic acid levels.
The results indicate that the reduction in hyaluronic acid levels plays an
important role in the occurrence of dry skin in diabetes" - See
collagen supplements at Amazon.com and
hyaluronic acid at Amazon.com.
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The impact of vitamin D
supplementation as an adjuvant therapy on clinical outcomes in patients with
severe atopic dermatitis: A randomized controlled trial - Pharmacol Res
Perspect 2020 Dec - "Vitamin D supplementation with
standard treatment yielded positive clinical outcomes in mild and moderate
atopic dermatitis; however, the potential benefit of vitamin D in severe cases
remains unclear ... The patients were randomized to receive either vitamin D 3
1600 IU/day or placebo, plus baseline therapy of topical 1% hydrocortisone cream
twice daily for 12 weeks. The primary endpoints were the change in mean Eczema
Area and Severity Index (EASI) score at the end of the study and the mean
percent change in EASI score from baseline to week 12. Eighty-six subjects
completed the study. The treated group achieved a significant higher level of 25
hydroxy vitamin D (P < .001) compared to control group at week 12. The mean EASI
score was significantly lower in the treatment group compared to placebo group
(P = .035). The percent change in EASI score from baseline differed
significantly between the supplementation (56.44 ± 29.33) and placebo (42.09 ±
19.22) groups after intervention (P = .039). Vitamin D supplementation could be
an effective adjuvant treatment that improves the clinical outcomes in severe
atopic dermatitis" - [Nutra
USA] - See vitamin D at Amazon.com and
vitamin D
at iHerb.
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Effect of the Lactococcus
Lactis 11/19-B1 Strain on Atopic Dermatitis in a Clinical Test and Mouse Model
- Nutrients. 2020 Mar 14 - "Some lactic acid bacteria
(LAB) are known to improve atopic dermatitis (AD) through the regulation and
stimulation of the host immune system. In this study, we found that ingestion of
yogurt containing Lactococcus lactis 11/19-B1 strain (L. lactis 11/19-B1) daily
for 8 weeks significantly improved the severity scoring of atopic dermatitis
(SCORAD) system score from 38.8 ± 14.4 to 24.2 ± 12.0 in children suffering from
AD ... AD-like skin lesions on the dorsal skin and ear were most improved by L.
lactis 11/19-B1 intake among the five LAB species. In addition, analysis of CD4+
T cell subsets in Peyer's patches (PPs) and cervical lymph nodes (CLNs)
indicated that the intake of L. lactis 11/19-B1 generally suppressed all subsets
related to inflammation, i.e., Th1, Th2 and Th17, instead of activating the
suppressive system, Treg, in the AD mouse model. Histological observations
showed ingestion of L. lactis 11/19-B1 significantly suppressed severe
inflammatory findings, such as inflammatory cell filtration, epidermal erosion
and eosinophil infiltration. These results suggest that the immunomodulatory
effects of L. lactis 11/19-B1 contribute to improvements in AD pathology"
- [Nutra
USA]
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Skincare 101: The only products you need to get good skin - CNET, 1/1/20 -
"According to dermatologist Amie Sessa, you should
use a gentle cleanser and avoid using too-hot water (which can be harsh on your
face). Campbell's favorite cleansers are
Cetaphil Gentle, CeraVe Hydrating or
Skinceuticals Gentle Cleanser ... Once you
cleanse, you can immediately follow with a moisturizer, or add an antioxidant
serum before you moisturize if you'd like. "Antioxidants should be used during
the day, as this is when you are most exposed to sun and pollution. They cause
reactive oxygen species (i.e., free radicals) that break down collagen and
elastin (the building blocks of the skin) and mutate DNA leading to sagging,
dull and pigmented skin," Campbell says ... For dry or combination skin types
she recommends a moisturizing serum with Vitamin C and ferulic acid, and for
oily skin, an antioxidant serum that is lightweight or oil-free if you're prone
to breakouts. If you want to add an extra boost of hydration, hyaluronic acid is
a great option for layering under a moisturizer and works for most skin types.
It also layers well with other products and is gentle."
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Benefits of Hesperidin
for Cutaneous Functions - Evid Based Complement Alternat Med. 2019 Apr
2;2019:2676307 - "Hesperidin is a bioflavonoid, with high concentration in
citrus fruits. In addition to its well-known benefits for cardiovascular
function, type II diabetes, and anti-inflammation, recent studies have
demonstrated multiple benefits of hesperidin for cutaneous functions, including
wound healing, UV protection, anti-inflammation, antimicrobial, antiskin cancer,
and skin lightening. In addition, hesperidin enhances epidermal permeability
barrier homeostasis in both normal young and aged skin. The mechanisms by which
hesperidin benefits cutaneous functions are attributable to its antioxidant
properties, inhibition of MAPK-dependent signaling pathways, and stimulation of
epidermal proliferation, differentiation, and lipid production. Because of its
low cost, wide availability, and superior safety, hesperidin could prove useful
for the management of a variety of cutaneous conditions" - See
hesperidin at Amazon.com.
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You might be able to fight dry winter skin with these three nutrition hacks
- Washington Post, 1/23/19 - "Staying well hydrated
helps keep all of our bodily systems functioning smoothly, so at a minimum, you
should aim for the recommended daily intake of 91 ounces of liquid for women and
125 ounces for men, amounts which include not only water, but all nonalcoholic
liquids consumed ... Since most of us get plenty of omega-6, it’s a smart
strategy to focus on upping our intake of omega-3 ... Two nutrients bountiful in
richly hued fruit and vegetables which researchers have begun to home in on are
carotenoids (including beta-carotene, a form of vitamin A, lutein, zeaxanthin
and others) and vitamin C. They act as antioxidants, protecting cells from
damage, and they are essential for the skin’s growth and repair. "
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Effects of Turmeric
(Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence
- Phytother Res. 2016 May 23 - "Overall, there is early
evidence that turmeric/curcumin products and supplements, both oral and topical,
may provide therapeutic benefits for skin health" - See
curcumin products at Amazon.com.
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Dietary Supplementation
with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial
Effect on Cellulite Morphology - J Med Food. 2015 Dec;18(12):1340-8 -
"specific bioactive collagen peptides (BCP) on the
cellulite treatment of normal and overweight women. In total, 105 women aged
24-50 years with moderate cellulite ... 105 women aged 24-50 years with moderate
cellulite were randomized to orally receive a daily dosage of 2.5 g BCP or a
placebo over 6 months ... The results of the study demonstrated that a regular
ingestion of BCP over a period of 6 months led to a clear improvement of the
skin appearance in women suffering from moderate cellulite. Based on the current
data, it can be concluded that a long-term therapy with orally administered BCP
leads to an improvement of cellulite and has a positive impact on skin health"
- [Nutra USA] - Here's what I take: Peptan® Hydrolyzed Collagen Protein Powder - For Hair - Nails - Joint Pain Relief - Skin Care - Appetite Suppressant - Building Muscle - Bone Density - Osteopenia
at Amazon.com.
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Influence of
Topical, Systemic and Combined Application of Antioxidants on the Barrier
Properties of the Human Skin - Skin Pharmacol Physiol. 2016 Jan 23 -
"The
formation of free radicals in human skin by solar ultraviolet radiation is
considered to be the main reason for extrinsic skin aging. The antioxidants in
human tissue represent an efficient protection system against the destructive
action of these reactive free radicals ... The study included 5 groups of 15
volunteers each, who were treated for 2 months with antioxidant-containing or
placebo tablets, creams or a combination of antioxidant-containing tablets and
cream ... The verum cream had a positive influence on epidermal thickness,
elasticity and skin moisture, but the verum tablets improved the epidermal
thickness only. The combined application of verum tablets and creams led to a
significant improvement of all investigated skin parameters, whereas the
application of placebo tablets or cream did not influence any parameters" - See
OZ Naturals- THE BEST Vitamin C Serum For Your Face Contains Clinical Strength
20% Vitamin C + Hyaluronic Acid Anti Wrinkle Anti Aging Serum For A Radiant &
More Youthful Glow!, Protein Essentials Hydrolyzed Collagen Protein Powder with Peptan® (16oz)
at Amazon.com
and Sunkist Grower Select Blueberry Capsules, 500 mg, 90 Count Bottle.
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French
Maritime Pine Bark Extract (Pycnogenol®) Effects on Human Skin: Clinical and
Molecular Evidence - Skin Pharmacol Physiol. 2015 Oct 23 -
"the existing data provide compelling evidence that
Pycnogenol® intake does not only provide photoprotection, but may be used to (i)
reduce hyperpigmentation of human skin and (ii) improve skin barrier function
and extracellular matrix homeostasis" - See
Pycnogenol at Amazon.com.
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The effect of oral
collagen peptide supplementation on skin moisture and the dermal collagen
network: evidence from an ex vivo model and randomized, placebo-controlled
clinical trials - J Cosmet Dermatol. 2015 Sep 12 - "Skin dryness and an
accelerated fragmentation of the collagen network in the dermis are hallmarks of
skin aging. Nutrition is a key factor influencing skin health and consequently
its appearance. A wide range of dietary supplements is offered to improve skin
health. Collagen peptides are used as a bioactive ingredient in nutricosmetic
products and have been shown in preclinical studies to improve skin barrier
function, to induce the synthesis of collagen and hyaluronic acid, and to
promote fibroblast growth and migration ... Oral collagen peptide
supplementation significantly increased skin hydration after 8 weeks of intake.
The collagen density in the dermis significantly increased and the fragmentation
of the dermal collagen network significantly decreased already after 4 weeks of
supplementation. Both effects persisted after 12 weeks. Ex vivo experiments
demonstrated that collagen peptides induce collagen as well as glycosaminoglycan
production, offering a mechanistic explanation for the observed clinical
effects" - [Nutra
USA] - See Protein Essentials Hydrolyzed Collagen Protein Powder with Peptan® (16oz)
at Amazon.com. It's
the Rousselot Peptan collagen brand talked about in the
Nutra USA article. See the
Rousselot Peptan collagen website.
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Fruit,
Vegetable and Dietary Carotenoid Intakes Explain Variation in Skin-Color in
Young Caucasian Women: A Cross-Sectional Study - Nutrients. 2015 Jul 15 -
"Fruit and vegetables contain carotenoid pigments, which
accumulate in human skin, contributing to its yellowness. This effect has a
beneficial impact on appearance ... Higher combined fruit and vegetable intakes
(β = 0.8, p = 0.017) were associated with higher overall skin yellowness values.
Higher fruit combined fruit and vegetable intakes (β = 1.0, p = 0.004) were
associated with increased unexposed skin yellowness. Combined fruit and
vegetables plus dietary carotenoid intakes contribute to skin yellowness in
young Caucasian women. Evaluation of interventions using improvements in
appearance as an incentive for increasing fruit and vegetable consumption in
young women is warranted"
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Lifestyle and Youthful
Looks - Medscape, 7/7/14 - "In Dutch men, smoking,
having skin that went red in the sun, being outside in the sun most of the
summer, sunbed use, wearing false teeth and not flossing teeth were all
significantly associated (P < 0·05) with a total 9.3-year higher perceived
facial age in a multivariate model adjusting for chronological age. In Dutch
women, smoking, sunbathing, sunbed use, few remaining teeth and a low body mass
index (BMI) were associated with a total 10.9-year higher perceived facial age.
In English women, cleaning teeth only once a day, wearing false teeth, irregular
skin moisturization and having skin that went red in the sun were associated
with a total 9.1-year higher perceived facial age. Smoking and sunbed use were
associated more strongly with wrinkling in women than in men. BMI, sun exposure
and skincare were associated predominantly with perceived facial age via
wrinkling, whereas oral care was associated via other facial features"
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Eat your
fruits, vegetables for skin with sun-kissed glow - Science Daily, 8/27/14 -
"Skin coloration can arise as a result of two distinct
processes," explain the team leading the research: through tanning (melanisation)
or the assimilation of fruit and vegetables (carotenoid ingestion) ... Results
from both studies showed a clear preference for strong color values; 86% of the
attendants to the first study voted for the high carotenoid version, while 78.5%
of the participants to the second one opted for the high melanin variant ... in
a third and final study, the team pitched 24 high carotenoid and high melanin
faces against each other, asking attendants to choose the one deemed more
appealing; results showed a 75.9% preference for carotenoid coloring over the
melanin one" - See
carotenoids at Amazon.com.
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Top 4 Foods for Thicker, Shinier Hair - ABC News, 4/29/14 -
"Yogurt ... These good bacteria help balance the
community of microorganisms that live in our intestines. And a recent study by
MIT researchers suggests that probiotics help produce that “healthy glow” we all
want, by making skin more radiant and hair more shiny, thick, and lustrous ...
The researchers suggest that probiotics decrease inflammation in the top layers
of the skin leading to healthier skin and hair ... Vitamin D is essential for
keeping your hair growing strong and preventing breakage—it helps keep the
follicles healthy, through the growth, shedding, and regrowth of new hairs ...
Zinc is a powerful nutrient for hair growth—it helps accelerate the repair of
damaged hair follicles, which keeps your hair healthy through all of its growth
phases. Zinc deficiency is also associated with hair loss ... The brassicas
(cabbage, Brussels sprouts, broccoli, kale) are packed full of healthy nutrients
and have been shown to help decrease the risk of heart disease and cancer. They
are also rich in phosphatidic acid, little fatty acid messengers involved in
cell creation and survival. A study in the Journal of Investigative Dermatology
found that phosphatidic acid also promotes hair growth due to its
growth-promoting effects on the cells in our hair follicles"
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Younger Skin Through Exercise - NYTimes.com, 4/16/14 -
"The scientists biopsied skin samples from each
volunteer and examined them microscopically. When compared strictly by age, the
skin samples overall aligned with what would be expected. Older volunteers
generally had thicker outer layers of skin and significantly thinner inner
layers ... But those results shifted noticeably when the researchers further
subdivided their samples by exercise habits. They found that after age 40, the
men and women who exercised frequently had markedly thinner, healthier stratum
corneums and thicker dermis layers in their skin. Their skin was much closer in
composition to that of the 20- and 30-year-olds than to that of others of their
age, even if they were past age 65 ... the researchers next set a group of
sedentary volunteers to exercising ... I don’t want to over-hype the results,
but, really, it was pretty remarkable to see ... Under a microscope, the
volunteers’ skin “looked like that of a much younger person, and all that they
had done differently was exercise"
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New Treatments For Blotchy Skin - ABC News, 3/24/14 -
"Niacinimide ... This is an ingredient used in some “cosmeceuticals,”
particularly in moisturizers. Halder says it prevents small melanin particles
(what turns your skin brown) from moving from the bottom layer to the top layer
of the skin. It is a form of vitamin B3 that blocks the pigment pockets from
moving to the skin’s surface ... Ellagic Acid ... The name sounds scary, but it
is actually derived from strawberries, cherries and pomegranates" - Note:
It seems like you could raise the good cholesterol at the same time by taking
niacin:
-
What Is the Difference Between Niacin & Niacinamide? - LiveStrong.com -
"Your body can convert niacin into niacinamide ...
Niacin and niacinamide have identical function when used as vitamins ...
their pharmacologic properties differ. For example, high doses of niacin can
cause skin flushing. Niacinamide, however, does not have the same
vasodialating, or blood-vessel widening, effects, that niacin has, so it
does not lead to skin flushing" - Note: You'll find
contradictory information on the Internet but niacinamide will not raise HDL
and niacin will. See
niacin at Amazon.com.
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Foods that help save your skin - The Washington Post, 2/26/14 -
"Antioxidants ... Omega 3 fatty acids ... Vitamin A ...
Zinc ... Water ... probiotic supplement in the diet to help restore good
bacteria to the digestive tract ... skin enemies ... Sugary foods ... Processed
fats and oils such as trans fats, corn oil, vegetable oil and canola oil"
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Gamma-Linolenic Acid Levels Correlate with Clinical Efficacy of Evening Primrose
Oil in Patients with Atopic Dermatitis - Adv Ther. 2014 Jan 17 -
"Atopic dermatitis (AD) has been related to a deficiency
of delta-6-desaturase, an enzyme responsible for the conversion of linoleic acid
to gamma-linolenic acid (GLA). Evening primrose oil (EPO) contains high amounts
of GLA. Therefore, this study investigated whether EPO supplementation results
in an increase in plasma GLA and its metabolite dihomo-gamma-linolenic acid
(DGLA) correlating with clinical improvement of AD, assessed by the SCORing
Atopic Dermatitis (SCORAD) index ... The clinical disease activity under EPO
treatment correlates with the individual increase in plasma GLA levels. Thus,
the results of this pilot study indicate that an increase in plasma GLA might be
used as predictive parameter for responsiveness of AD to EPO therapy" -
See
evening primrose oil
at Amazon.com.
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The best foods for clear skin - washingtonpost.com, 9/18/13 -
"Stay away from anything that comes in a box ...
both because of the added sugars and because of other additives ... gobble
up produce of all colors, plus nuts and seeds, to get minerals, fiber and
vitamins A, C and E ... Foods that keep your blood sugar low are also good
for the skin ... avoid sugar ... omega-3 fatty acids, which are found in
wild salmon, help support healthy cell membranes ... Another smart move is
the addition into the diet of probiotics, which can be found in yogurt and
kefir as well as nutritional supplements. (She prefers supplements over
yogurt because they contain much higher amounts of probiotics.)" -
See
Garden of Life Primal Defense HSO Probiotic Formula at Amazon.com.
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5 Foods for Healthy Skin - ABC News, 9/12/13 -
"Strawberries ... Olive oil ... Green tea ... Pumpkin ... Pomegranate"
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Sleep deprivation linked to aging skin, study suggests - Science Daily,
7/23/13 - "Our study is the first to conclusively
demonstrate that inadequate sleep is correlated with reduced skin health and
accelerates skin aging. Sleep deprived women show signs of premature skin
aging and a decrease in their skin's ability to recover after sun exposure
... The study involved 60 pre-menopausal women between the ages of 30 and
49, with half of participants falling into the poor quality sleep category
... Using the SCINEXA skin aging scoring system, poor quality sleepers
showed increased signs of intrinsic skin aging including fine lines, uneven
pigmentation and slackening of skin and reduced elasticity. In this system,
a higher score means a more aged appearance. The average score in the good
quality sleepers was 2.2 versus 4.4 in poor quality sleepers"
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Lutein, Zeaxanthin, and
Skin Health - Medscape, 6/7/13 - "Results from
cell culture and animal studies showing that lutein and zeaxanthin exhibit
positive skin health benefits have considerable merit and suggest an avenue
by which these carotenoids may function. The results from one human study
demonstrate that orally administered lutein and zeaxanthin can inhibit lipid
peroxidation on the surface of the skin and help bolster the skin's
photoprotective activity, potentially protecting the skin from exposure to
light, particularly UV light. Since the typical diet of people in the United
States is about 2 mg of lutein per day, due to the ingestion of foods such
as green leafy vegetables that contain the highest levels of diet-derived
lutein and zeaxanthin,[15] it may be considered advisable to increase the
daily intake of lutein and zeaxanthin for optimal skin health and
photoprotection" - See
Jarrow Formulas, CarotenALL at Amazon.com.
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9 Best Foods for Your Skin - US News and World Report, 5/16/12 -
"Tomatoes ... Mangoes, papaya, and apricots ...
Cocoa powder ... Flaxseeds ... Sweet potatoes ... Mussels ... Spinach ...
Canned tuna ... Safflower Oil" - Note: I'm not buying the chocolate
or safflower oil suggestions.
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Do Fruits and Veggies Make You More Attractive? - WebMD, 3/7/12 -
"changes in the redness and yellowness of skin in
white people may be linked to the number of servings of fruit and vegetables
they eat on a daily basis. These antioxidant-rich foods, which are loaded
with plant-based pigments, seem to affect skin tone ... They suggest it's
the carotenoids -- the red, yellow, and orange pigments in fruits and
vegetables -- that play an important role in skin tone. Foods such as
carrots, sweet potatoes, squash, and apricots are rich in beta-carotene, as
are some dark green vegetables, including spinach and kale ... Another
carotenoid is lycopene, which is found in tomatoes and pink grapefruits"
- See
Jarrow Formulas, CarotenALL at Amazon.com
and
Garden of Life, Radical Fruits Antioxidant Complex at Amazon.com.
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Which Foods Can Help Your Skin Look Better - CBS Chicago, 7/14/11 -
"Experts say that what you eat has a big effect on
how you look ... people who switched to a hypoglycemic – or low sugar – diet
for three months reduced their pimples by 20 percent ... So what should we
eat to prevent or even get rid of wrinkles? ... What you want to do is build
up the collagen and there’s certain collagen builders, such as Vitamin C and
Vitamin E ... To avoid dry, flaky skin or eczema, increase your omega 3s ...
There’s less scientific proof about cellulite, but many nutritionists also
feel you can reduce the appearance of those unsightly bulges by eating dark
red and purple foods, which help rid the body of toxins – things like
cranberry juice, blueberries, cherries and radicchio lettuce ... If you’re
looking for a cure-all for nearly any skin problem, it’s extra virgin olive
oil. It helps reduce inflammation, and can help everything from psoriasis to
eczema to acne .. dairy, even skim-milk, seems to make nearly every skin
problem worse"
-
Eating vegetables gives skin a more healthy glow than the sun, study shows
- Science Daily, 1/11/11 - "people who eat more
portions of fruit and vegetables per day have a more golden skin colour,
thanks to substances called carotenoids. Carotenoids are antioxidants that
help soak up damaging compounds produced by the stresses and strains of
everyday living, especially when the body is combating disease. Responsible
for the red colouring in fruit and vegetables such as carrots and tomatoes,
carotenoids are important for our immune and reproductive systems ... given
the choice between skin colour caused by suntan and skin colour caused by
carotenoids, people preferred the carotenoid skin colour" - See
Jarrow Formulas, CarotenALL, Mixed Carotenoid Complex at Amazon.com.
-
Pomegranate compounds show skin health potential - Nutra USA, 8/10/10 -
"ellagic acid may prevent the degradation of
collagen in human skin cells, which would maintain skin structure and slow
the formation of wrinkles ... Topical or dietary interventions with berries
and pomegranate rich in ellagic acid and ellagitannins are promising
strategies in curtailing skin wrinkling and cutaneous inflammation
associated with chronic UV exposure leading to photoageing" - [Abstract]
- See
pomegranate at Amazon.com.
-
Dietary compound ellagic
acid alleviates skin wrinkle and inflammation induced by UV-B irradiation -
Exp Dermatol. 2010 Aug;19(8):e182-90 - "Ellagic acid, a
polyphenol compound present in berries and pomegranate, has received attention
as an agent that may have potential bioactivities preventing chronic diseases
... These results demonstrate that ellagic acid prevented collagen destruction
and inflammatory responses caused by UV-B. Therefore, dietary and
pharmacological interventions with berries rich in ellagic acid may be promising
treatment strategies interrupting skin wrinkle and inflammation associated with
chronic UV exposure leading to photoageing" - See
pomegranate at Amazon.com.
-
Lack
of omega-6 fatty acid linked to severe dermatitis - Science Daily,
4/14/10 - "Without arachidonic acid, the mice
developed severe ulcerative dermatitis. The animals were very itchy, they
scratched themselves continuously, and they developed a lot of bleeding
sores" - Note: I doubt if that's a problem in America where they get
way to much omega-6 already.
-
New
Role Of Vitamin C In Skin Protection; Relevance To The Cosmetics Industry
- Science Daily, 9/8/09 - "a form of Vitamin C
helped to promote wound healing and also helped protect the DNA damage of
skin cells ... Previously, the group has published evidence that DNA repair
is upregulated in people consuming vitamin C supplements ... The results
demonstrated that vitamin C may improve wound healing by stimulating
quiescent fibroblasts to divide and by promoting their migration into the
wounded area. Vitamin C could also protect the skin by increasing the
capacity of fibroblasts to repair potentially mutagenic DNA lesions ... Free
radicals are associated with premature skin aging, and antioxidants, such as
vitamin C, are known to counter these highly damaging compounds. This new
evidence suggest that, in addition to ‘mopping up’ free radicals, vitamin C
can help remove the DNA damage they form, if they get past the cell’s
defences"
-
Better skin from the beauty aisle - MSNBC, 1/18/09 - Has a doctor's
evaluation of various skin aging solutions.
-
LycoRed files patent for skin health science - Nutra USA, 11/7/08 -
"According to LycoRed, subjects were supplemented by
either Lyc-O-Mato capsules (10mg lycopene per day), or a placebo, for ten
weeks. Following exposure to UV radiation at the end of the study, it was
found that subjects in the tomato extract group had a sunburn cell count six
times lower than in the placebo group. There was also evidence of reduced
depletion of Langerhans cells, said the company" - See
Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com.
-
Vitamin D may protect skin from within: Study - Nutra USA, 10/8/08 -
"Atopic dermatitis (AD) ... All of the participants
were given daily vitamin D supplements of 4000 IUs for 21 days ... After
supplementation, the skin of people with AD showed statistically significant
increases in cathelicidin from 3.53 to 23.91 relative copy units (RCU).
Moreover, normal skin showed a “modest increase”, said the researchers, from
1.0 to 1.78 RCU" - See
vitamin D at Amazon.com.
-
Flax and borage oil may boost skin health from within - 10/3/08 -
"the researchers noted a significant decrease in
reddening of the skin in the flaxseed and
borage oil groups of 45 and 35 per
cent, respectively, compared to baseline values. No differences were
recorded in the placebo group ... blood flow to the in skin also decreased
in the oil groups ... Measurements of water loss from the skin showed that
the oil supplements were associated with decreases of about 10 per cent
after six weeks, with only the flaxseed oil group showing further decreases
at the end of 12 weeks (25 per cent) ... The roughness and scaling – dry
peeling skin – was also decreased significantly after 12 weeks of flaxseed
and borage oil supplementation, with no differences in the placebo group"
- [Abstract]
-
What
To Eat For Glowing Healthy Skin - Science Daily, 11/14/07 -
"the antioxidants in vitamins C and E can protect
the skin from sun damage and help reduce damage in skin cells caused by
harmful free radicals, which contribute to aging skin. Similarly, we have
long known that the B vitamin biotin is responsible for forming the basis of
skin, hair and nail cells, and vitamin A – found in many fruits and
vegetables – maintains and repairs skin tissue"
-
On
The Cover: Scientifically Advanced Skin Care - Life Extension Magazine,
1/07
-
Eat
Right To Keep Healthy Skin - CBS 2 Chicago, 4/30/05 -
"Clinical studies have found that eating a diet rich
in fruits, vegetables, whole grains, legumes and omega-3 fatty acids can
help skin retain its healthy glow and look youthful ... foods for healthy
skin include those rich in lycopene. That's a pigment that gives many fruits
and vegetables their red color. It's a proven antioxidant, and antioxidants
are important because they reduce the risk of several types of cancer and
they prevent the formation of harmful byproducts of metabolism called free
radicals"
-
Rub Away Aged Skin - Life Extension Magazine, 6/04
- What do you recommend for
thin, dry skin and hair and brittle nails? - Dr. Weil, 10/21/03
-
Rejuvenate Your Skin While You Sleep - Life Extension Magazine cover
story, 8/03
-
Green Tea Gives Skin Healthy Glow - HealthDay, 5/15/03 -
"Green tea contains
compounds called polyphenols, which help eliminate free radicals. These free
radicals can cause cancer by altering DNA. Polyphenols also protect healthy
cells while promoting the death of cancer cells ... Cells that migrate
toward the surface of the skin normally live about 28 days, and by day 20
they basically sit on the upper layer of the skin getting ready to die. But
EGCG reactivates them ... EGCG may offer potential benefits for skin
conditions including psoriasis,
rosacea, wrinkles
and wounds" - See
iHerb green tea extracts. My favorite is
Jarrow green tea at iHerb.
- GLA: The Right Remedy
for Eczema? - Dr. Weil, 11/21/02 -
"It has specific nourishing effects on skin, hair,
and nails that are not duplicated by omega–3
fatty acids ... It is true that a high ratio of
omega-6 to omega-3 fatty acids in the diet promotes
inflammation by favoring synthesis of pro-inflammatory hormones
(prostaglandins). But the amount of
GLA needed to treat eczema and other skin
conditions (500 milligrams twice a day) is too small to affect that ratio
significantly" - See
gamma linolenic acid at Amazon.com.
-
Increased Blood Antioxidants And Selenium Levels May Augur A Promising
Therapy For Patients With Vitiligo - Doctor's Guide, 11/8/02
-
Link Found Between Vitamin E Intake and Immunoglobulin E In Treatment Of
Atopic Dermatitis - Doctor's Guide, 5/31/02 -
"Dietary
vitamin E (VE) could be an excellent tool in
treating
atopic dermatitis"
-
Nutrition for the Skin - What You Should Know Before Undergoing a Surgical
Procedure - Wellness Insider, 5/23/02 -
"free radicals can accelerate the aging process of
the skin, resulting in wrinkles and sunspots,
not to mention an increased risk of skin cancer ... These
antioxidants are important in protecting you from disease and can help
shield you from skin cancer, maintain youthful, healthy skin, and even help
to promote and expedite the healing process after a surgical procedure"
- Few Vitamins
Effectively Prevent or Reverse Skin Damage - Medscape, 3/02 -
"Despite advertising claims, almost all available
topical formulations contain very low concentrations of antioxidants that
are not well absorbed by the skin ... There are 3 antioxidants that have
been proven to decrease the effect of the sun on the skin and actually
prevent further damage: selenium,
vitamin E, and vitamin C ... Recent animal
studies have found that when selenium is taken orally or through the skin in
the form of L-selenomethionine, it provided protection against both everyday
and excessive UV damage ... New laboratory studies suggest vitamin E helps
inactivate free radicals, making them less likely to cause damage ... Even
minimal UV exposure can decrease the vitamin C levels in the skin by 30%,
while exposure from the ozone of city pollution can decrease the level by
55%"
-
Topical Vitamin C May Have Beneficial Effect On Photaged Skin - Doctor's
Guide, 4/13/01 -
"vitamin C levels of
the skin can be severely depleted following UV irradiation ... By comparison
with placebo controls, there was a highly significant increase in the skin
microrelief density and a decrease of the deep furrows on the side of the
neck treated with Vitamin C cream"
Other Information:
-
6 common skincare mistakes that can wreck your skin - CNET, 1/1/20 -
"Essential oils may be all the rage, but it
turns out they may not be great directly on your skin ... "I'm not saying
that none of them are safe, but essential oils are often extremely
concentrated and can cause skin reactions. 'Natural' does not always equate
to good for the skin (poison ivy is natural, too!)," Sessa said. Campbell
agrees, saying that many essential oils are a cause of contact skin
allergies. She recommends avoiding them (and other fragrance in products) if
you experience rash or irritation"
-
For
vitiligo patient, arthritis drug restores skin color - Science Daily,
6/24/15 - "Within two months of treatment, the
patient experienced partial repigmentation on her face, arms, and hands --
the areas that concerned her most. After five months, the white spots on her
face and hands were nearly gone, with only a few spots remaining on other
parts of her body. Notably, tofacitinib caused no adverse side effects
during the course of treatment" - Note: Tofacitinib is the one that
also grows hair if you can afford the price tag. Here's a cut and
paste from a previous newsletter:
-
Hairless Man Now Hairy, Thanks to Arthritis Drug - WebMD, 6/20/14 -
"After three more months taking 15 milligrams a day of
the drug, he had a full head of hair and clearly visible eyebrows and eyelashes,
as well as facial, armpit and other hair ... Tofacitinib citrate (marketed as
Xeljanz) is used to treat rheumatoid arthritis" -
NBC News has better pictures of the spectacular results.
It only runs about $42 per 5 mg tablet
and you need three per day so about $126 per day. No problem for the
average person.
-
WHO: Tanning Beds Cause Cancer - WebMD, 7/28/09
-
Human Skin Crawling With Bacteria - WebMD, 5/28/09
-
Really? -
Drinking Lots of Water Is Good for Your Skin - NYTimes.com, 10/27/08
-
New
Ingredients In Drug-like Anti-aging Products Improve Skin - Science
Daily, 12/28/07 - "skin surface irregularity can be
improved through the topical application of niacin, while the appearance of
fine lines can be diminished through the application of moisturizers
containing engineered peptides and over-the-counter retinoids. Skin
pigmentation can become more regular with the use of photoprotective
ingredients. Furthermore, combining cosmeceutical ingredients in a
moisturizing agent can magnify benefits and improve skin appearance"
-
Antiaging Skin Care: Reversing Skin Aging By Gene Blockade In Mice -
Science Daily, 11/29/07
-
11 Causes of Dry Skin Problems - WebMD, 11/29/07
-
Retinol May Smooth Aging Skin - WebMD, 5/22/07
-
Vitamin A Helps Reduce Wrinkles Associated With Natural Skin Aging -
Science Daily, 5/21/07 - "Applying vitamin A to the
skin appears to improve the wrinkles associated with natural aging and may
help to promote the production of skin-building compounds ... Researchers
applied a lotion containing 0.4 percent retinol"
- Is Zapping Hair Safe?
- Dr. Weil, 5/28/03
-
Oral Terbinafine With Topical Ciclopirox Clears Toenail Onychomycosis Faster
- Doctor's Guide, 3/26/03
-
Tacrolimus 0.1% Ointment Safe and Effective Long-Term for Atopic Dermatitis
in Children and Adults - Doctor's Guide, 3/24/03
-
Bexarotene Gel May Be New Option for Hand Dermatitis - Doctor's Guide,
3/24/03
-
Dangerous Pigmentation Recognized By Computerized-Image Analysis -
Doctor's Guide, 3/14/03
- New Skin Cream
[Avage] Reverses Sun Damage - WebMD, 11/22/02 -
"At the 24-week point, researchers found
significantly more patients who used the
tazarotene cream
experienced a more than 50% overall improvement in skin appearance compared
to those who received the placebo. The Avage users also reported less
wrinkling, mottled pigmentation, and skin
roughness"
-
FDA Approves First One-Day, Oral Antiviral Treatment of Cold Sores -
Doctor's Guide, 9/10/02
-
Pimecrolimus Cream Helps Control Atopic Dermatitis in Adults - Doctor's
Guide, 7/3/02
-
Atopic Dermatitis Symptoms Improve with Clobetasol Propionate 0.5 Percent
- Doctor's Guide, 7/3/02
-
Rubefacients Protect Skin Against Moderate Cold - Doctor's Guide, 7/1/02
- The Right Way to
Apply Sunscreen - WebMD, 6/20/02 -
"The sun protection factor, or SPF, that a sunscreen
delivers is determined by testing skin that's been generously slathered with
a thick coat of sunscreen. But studies have shown that most people apply
only 25% to 75% of this amount"
-
Many Children At Risk Of Skin Cancer - Doctor's Guide, 6/3/02
-
Navigating the maze of sunscreens - CNN, 5/28/02
- Stress Hormone
Behind Bad Skin - WebMD, 5/17/02 -
"In response to stress, the brain signals production
of several hormones. One of them is stress hormone, which makes the oil
glands in the skin go into overdrive. Triggering of the stress system can
also lead to hair loss, skin aging, and other skin problems" - I
believe they are talking about cortisol.
Phosphatidylserine (PS) is believed to reduce
cortisol.
-
Reducing The Risk Of Occupational Hand Dermatitis - Doctor's Guide,
4/15/02
- Smokers Look
Older -- Butt Why? - WebMD, 3/22/02 -
"Bottom line: Smokers get a double whammy -- once
from the sun and again from tobacco, since both trigger this
skin-destructive MMP-1 action"
-
Low-Dose Topical 5-Fluorouracil As Effective, Better Tolerated Than Standard
5% Cream - Doctor's Guide, 2/26/02
- Study Links Tanning
Beds to Skin Cancer - WebMD, 2/5/02 -
"those who had ever used a tanning bed were 2.5
times more likely to have squamous cell cancer and 1.5 times more likely to
have basal cell cancer ... those that started using tanning beds at an
earlier age tended to be more likely to end up with skin cancer"
- Solaraze (Diclofenac
Sodium) Gel, For Treatment Of Actinic Keratosis, To Be Available In US In
January 2002 - Doctor's Guide, 12/10/01
- Lower Dose Tretinoin Cream
As Effective, Less Irritating Than Higher Doses In For Photodamaged Skin
- Doctor's Guide, 8/2/01
- Abreva (Docosanol 10%)
Speeds Healing of Cold Sores - Doctor's Guide, 7/25/01
- Cancer Risk From
Tanning Beds Similar to Direct Sunlight - WebMD, 6/6/01 - "ultraviolet
exposure from tanning beds is just as dangerous as direct exposure to the
sun"
- Gatifloxacin Proves Of
Value For Treating Dermatological Infections - Doctor's Guide, 7/4/01
- Tanning Salon Exposure Can
Lead to Skin Cancer - Doctor's Guide, 5/29/01
- FDA Approves Avelox
(Moxifloxacin HCl) for Treatment of Uncomplicated Skin Infections -
Doctor's Guide, 4/30/01
-
Research On Why Smokers Look Older - Intelihealth, 3/23/01 -
"smoking switches on a gene involved in destroying
collagen, the structural protein that gives skin its elasticity ... Smoking
has also been found to trigger oxygen damage to the cells and to mess up the
blood flow to the skin"
- 59th Annual Meeting of
the American Academy of Dermatology - Medscape, 3/7/01
- New Photorejuvenation
Treatments Effective For Aging Skin - Doctor's Guide, 3/6/01
- Hygiene of the Skin:
When Is Clean Too Clean? - Medscape, 3/01
- Herpes Virus
Shows Early Promise for Advanced Skin Cancer - WebMD, 2/15/01
- Zindaclin (ResiDerm A) Gel
As Effective As Dalacin T (Clindamyacin) Topical Lotion For Skin Disorders
- Doctor's Guide, 12/20/00
- Infrared
Technology: A New Answer to 'Tattoo Regret' - WebMD, 10/20/00
- FDA Approves New
Indication For Levaquin (Levofloxacin) For Skin Infections - Doctor's
Guide, 9/15/00
- FDA Approves New
Formulation Of Renova (Tretinoin Cream) For Reduction Of Fine Facial
Wrinkles - Doctor's Guide, 9/6/00
- New Laser
Promises Clearer Skin With Less Pain - WebMD, 8/24/00
- For Acne Scars,
Laser Resurfacing Is Popular, Effective - WebMD, 5/16/00
- More Sun Equals
More Skin Cancer -- Even for Blacks - WebMD, 4/14/00
- FDA Approves Levulan
Kerastick For Pre-Cancerous Skin Lesions - Doctor's Guide, 12/7/99
-
The ABCs of SPFs: What's new under the sun - CNN, 8/13/99
- Vernix Replicates Human
Skin’s Natural Protective Properties - Doctor's Guide, 12/23/98
- Tanning Beds: Hotbed Of
Controversy - Doctor's Guide, 10/30/97
- Tiny Skin Flaws Contain
Genetic Mutations Linked To Cancer - Doctor's Guide, 6/11/97
- Prescription Skin Protector
Helps Prevent Environmental Aging - Doctor's Guide, 3/27/97
- Poison Ivy, Oak and Sumac
Skin Protectant Now Available - Doctor's Guide, 3/20/97
- Spring and Summer Skin
Irritations - How to Fight the Fungus Among Us - Doctor's Guide, 5/29/96
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