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Home > Health Conditions > PTSD

Posttraumatic Stress Disorder

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  • Abnormal gut bugs tied to worse cognitive performance in vets with PTSD and cirrhosis - Science Daily, 9/12/19 - "A study involving military veterans with PTSD and cirrhosis of the liver points to an abnormal mix of bacteria in the intestines as a possible driver of poor cognitive performance -- and as a potential target for therapy ... the findings add to the substantial evidence linking gut health and brain function ... Those with PTSD had microbiota that were less diverse, meaning they had fewer types of bacteria overall ... These veterans, along with the relative lack of diversity in their gut, tended to have more potentially harmful types of bacteria, such as Enterococcus and Escherichia/Shigella, and fewer beneficial ones, such as Lachnospiraceae and Ruminococcaceae ... He cited probiotic supplements or fecal transplants as two possible therapy approaches" - See probiotic products at Amazon.com.
  • Comparing Perika St. John's Wort and Sertraline for Treatment of Posttraumatic Stress Disorder in Mice - J Diet Suppl. 2019 Feb 18:1-9 - "exaggerated acoustic startle response (ASR) ... Thirty-six mice were tested for baseline ASR, then they were exposed to rats in a predator exposure paradigm known to induce PTSD-like symptoms. Mice were randomly divided into three groups for treatment (control, sertraline, SJW), and ASR was retested one week later. One-way ANOVAs found no significant group differences in ASR amplitude at baseline but a significant effect of Treatment Group after predator exposure, F(2, 33) = 5.645, p = .008, n2 = .225, when SJW-treated mice had ASR amplitudes that were significantly lower than sertraline-treated mice (by 27%) and controls (by 26%). Fecal boli counts showed a similar pattern, with lowest counts in SJW-treated mice. These results suggest SJW could be considered for studies of PTSD treatment in humans as well" - See Perika St. John's Wort at Amazon.com.
  • Cannabis may hold promise to treat PTSD but evidence lags behind use - Science Daily, 9/3/19 - "The lack of evidence supporting cannabis as a PTSD treatment is striking ... Every study had medium to high risk of bias and all were assessed as low in quality due to limitations such as small sample size, retrospective study design, lack of a control group or placebo, short follow-up periods, and not reporting other medication use or addiction. Only one study was a randomised controlled trial, investigating nabilone, but it was in a small sample over a relatively short period of time ... The researchers say there are still many unanswered questions about the safety and efficacy of cannabis-based medications for PTSD, and potential long-term effects such as addiction or a risk of psychosis ... Current prescribing of cannabinoids for PTSD is not backed up by high quality evidence"
  • Supplementation with Robuvit® in post-traumatic stress disorders associated to high oxidative stress - Minerva Med. 2018 Oct;109(5):363-368 - "After 4 weeks, the percentages of subjects with recurrent memories and dreams, transient walking-dissociative states and reactive flashbacks/hallucinations, alarm reactions and intense emotional distress, emotional numbness, social disinterest and detachment were significantly lower in the subjects treated with Robuvit® (P<0.05%). Sleeping problems, irritability, and fatigue were also significantly reduced with supplementation." - [Nutra USA] - See Robuvit® at Amazon.com.
  • Effects of omega-3 polyunsaturated fatty acids on psychophysiological symptoms of post-traumatic stress disorder in accident survivors: A randomized, double-blind, placebo-controlled trial - J Affect Disord. 2016 May 30 - "A total of 83 participants received either omega-3 PUFAs (1470mg docosahexaenoic acid and 147mg eicosapentaenoic acid per day) or placebo within 10 days of the accidental injury. After 12-week supplementation, participants performed script-driven imagery of their traumatic event during monitoring of their heart rate and skin conductance ... Analysis revealed that heart rate during both rest and script-driven imagery was significantly lower in the omega-3 group than the placebo group, whereas baseline heart rate was comparable between the two groups" - [Nutra USA] - See docosahexaenoic acid at Amazon.com.
  • Blueberries show promise as treatment for post-traumatic stress disorder - Science Daily, 3/31/15 - "Ebenezer et al. have previously demonstrated that SSRIs increase levels of serotonin (5-HT) and the neurotransmitter norepinephrine (NE) and that the increased NE may reduce the effectiveness of SSRI therapy. In the new study, the research team looked at the ability of blueberries to modulate neurotransmitter levels in a rat model of PTSD ... PTSD rats who did not receive blueberries demonstrated a predictable increase in NE and 5-HT when compared with the control group. However, the PTSD rats that received blueberries showed a beneficial increase in 5-HT with no effect on NE levels, suggesting that blueberries can effectively modulate neurotransmitters in PTSD" - Note:  That's probably another one that's a better alternative to pot for people who claim pot helps their PTSD when there's no evidence to support it and it's probably just a con-game to get high.  See Garden of Life, Radical Fruits Antioxidant Complex at Amazon.com.
  • Medical Marijuana May Worsen PTSD Symptoms, Increase Violence - Medscape, 12/15/14 - "A large observational study of more 2000 participants who were admitted to specialized Veterans Administration treatment programs for PTSD showed that those who never used marijuana had significantly lower symptom severity 4 months later than those who continued or started use after treatment. Veterans who were using marijuana at treatment admission but quit after discharge ("stoppers") also had significantly lower levels of PTSD symptoms at follow-up ... On the other hand, the highest levels of violent behavior were found in the so-called "starters," those who were not using the substance at admission but who started use after discharge"

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