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Preeclampsia

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• Pregnancy

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• aspirin / omega-3 / magnesium

Alternative News:

• Association of maternal vitamin D status with the risk of preeclampsia - Food Funct 2023 May 2 - "Our finding of lower vitamin D concentrations in mid-pregnancy, before women developed clinical preeclampsia, suggests that vitamin D may have a role in its pathophysiology" - See vitamin D at Amazon.com.
• Association between Folic Acid Supplementation and Hypertensive Disorder Complicating Pregnancy in Jiangsu Province: A Cross-Sectional Study - Evid Based Complement Alternat Med 2022 Sep 6 - "hypertensive disorder complicating pregnancy (HDCP) ... Maternal women with and without FA supplement intake were compared in this study. FA supplementation included 0.4 mg FA (0.4 FA), multivitamins with 0.4 mg FA (multivitamin (MV)+0.4 FA), and multivitamins with 0.8 mg FA (MV + 0.8 FA) ... MV supplement with 0.8 mg FA during early pregnancy may be effective in reducing HDCP and preeclampsia risk" - See folic acid products at Amazon.com.
• L-citrulline ameliorates pathophysiology in a rat model of superimposed preeclampsia - Br J Pharmacol 2021 Dec 22 - "Preeclampsia, characterized by hypertension, proteinuria, and fetal growth restriction, is one of the leading causes of maternal and perinatal mortality. By far, there is no effective pharmacological therapy for preeclampsia ... This study shows that L-citrulline supplementation reduces gestational hypertension, improves placentation and fetal growth in a rat model of superimposed preeclampsia. L-citrulline supplementation may represent an effective and safe therapeutic strategy for preeclampsia that benefit both the mother and the fetus" - See L-citrulline at Amazon.com.
• Dietary and serum vitamin D and preeclampsia risk in Chinese pregnant women: a matched case-control study - Br J Nutr 2021 Aug 6 - "this study provides evidence that higher dietary intake and serum levels of VD are associated with the lower risk of PE in Chinese pregnant women" - See vitamin D at Amazon.com and vitamin D at iHerb.
• Higher manganese levels in early pregnancy linked to lower preeclampsia risk - Science Daily, 7/7/30 - "These new findings are especially relevant, considering that preeclampsia rates are increasing and we still lack any good strategy for preventing it ... higher manganese levels in the first trimester were associated with a lower risk of preeclampsia later in the pregnancy, depending on the dose. This suggests that incrementally more manganese would bring incrementally less risk. The researchers divided the women into three equally sized groups according to their measured manganese levels -- low, medium, and high -- and found that those in the high-manganese group had just half the risk of preeclampsia, compared to those in the low-manganese group" - See manganese at Amazon.com and iHerb.
• Bit of Chocolate in Pregnancy May Help Mom, Baby - WebMD, 2/4/16 - "Pregnant women who nibble just a small piece of chocolate each day may improve the circulatory health of their unborn child ... The tiny treat may also reduce the risk for preeclampsia ... All were instructed to consume 30 grams of chocolate (a little more than one ounce) each day over a 12-week period. That's equivalent to about one small square of chocolate per day ... Half of the women consumed high-flavanol chocolate, while the other half were given low-flavanol chocolate ... simply consuming a small amount of chocolate -- no matter what the flavanol content -- was associated with notable improvements in all blood circulation and velocity measures compared to the general population" - See Ghirardelli Chocolate Intense Dark Squares, Midnight Reverie, 4.12 oz., 86% Cacao (Pack of 4) at Amazon.com.
• New study indicates that metformin has the potential to prevent and treat preeclampsia - Science Daily, 12/22/15 - "the drug metformin decreases the production of the two toxins elevated in preeclampsia and also helps heal injured blood vessels ... Metformin appears to be the aspirin of the 21st century, because the drug has been discovered to have unexpected health benefits not only in diabetes, but also in polycystic ovarian disease and recent work has highlighted its anti-cancer properties" - See metformin at The Antiaging Store.
• Low vitamin D levels during pregnancy may increase risk of severe preeclampsia - Science Daily, 1/27/14 - "researchers studied blood samples collected from 700 pregnant women who later developed preeclampsia in an effort to examine a woman's vitamin D status during pregnancy and her risk of developing preeclampsia ... also studied blood samples from 3,000 mothers who did not develop preeclampsia ... vitamin D sufficiency was associated with a 40 percent reduction in risk of severe preeclampsia. But there was no relationship between vitamin D and mild preeclampsia" - See vitamin D at Amazon.com.
• Probiotic intake linked to fewer birth complications - Nutra USA, 9/13/11 - "The Norwegian researchers analyzed data from 33,399 women participating in the Norwegian Mother and Child Cohort Study ... The intake of lactobacilli-containing milk-based products was determined using a food frequency questionnaire, while pre-eclampsia was determined using the Norwegian Medical Birth Registry ... the daily intake of at least 140 mL of probiotic milk products was associated with a 20% reduced risk of pre-eclampsia ... The effects were more pronounced for severe pre-eclampsia, with daily and weekly intakes of probiotic products associated with a 39% and 25%, respectively" - [Abstract] - See my yogurt recipe at the top of my Yogurt Page.  See probiotics at Amazon.com.
• Dietary Supplement May Help Prevent Preeclampsia - WebMD, 5/19/11 - "women who ate daily food bars containing the amino acid L-arginine and antioxidant vitamins during pregnancy had a much lower incidence of preeclampsia than women who ate bars containing the antioxidant vitamins alone or bars containing neither supplement ... far fewer of the women in the L-arginine plus vitamin group developed preeclampsia (12.7%) than women in the vitamin-alone (22.5%) group and no-supplement (30.2%) group" - See L-arginine products at Amazon.com.
• Serum Carotenoids and Fat-Soluble Vitamins in Women With Type 1 Diabetes and Preeclampsia: A longitudinal study - Diabetes Care. 2011 Apr 15 - "preeclampsia (PE) ... In pregnant women with type 1 diabetes, low serum α- and β-carotene were associated with subsequent development of PE, and vitamin D deficiency may also be implicated" - See Jarrow Formulas, CarotenALL at Amazon.com.
• A Nested Case-Control Study of Midgestation Vitamin D Deficiency and Risk of Severe Preeclampsia - J Clin Endocrinol Metab. 2010 Aug 18 - "Vitamin D may be important in the pathogenesis of severe preeclampsia ... Midgestation maternal 25(OH)D concentration was lower in women who subsequently developed severe preeclampsia compared with controls [median (interquartile range), 75 (47-107) nmol/liter vs. 98 (68-113) nmol/liter; P = 0.01]. Midgestation maternal 25(OH)D of less than 50 nmol/liter was associated with an almost 4-fold odds of severe preeclampsia (unadjusted odds ratio, 3.63; 95% confidence interval, 1.52-8.65) compared with midgestation levels of at least 75 nmol/liter. Adjustment for known confounders strengthened the observed association (adjusted odds ratio, 5.41; 95% confidence interval, 2.02-14.52). Conclusion: Maternal midgestation vitamin D deficiency was associated with increased risk of severe preeclampsia. Vitamin D deficiency may be a modifiable risk factor for severe preeclampsia" - See vitamin D at Amazon.com.
• New Link Between Pre-eclampsia And Diet - Science Daily, 8/25/09
• Vitamin D may reduce pre-eclampsia risk: Study - Nutra USA, 8/20/09 - See vitamin D at Amazon.com.
• CoQ10 may cut pre-eclampsia in high-risk women - Nutra USA, 4/1/09
• Maternal Vitamin D Deficiency May Increase Risk for Preeclampsia - Medscape, 6/3/08 - "Compared with controls, women who subsequently developed preeclampsia had lower adjusted serum 25(OH)D concentrations in early pregnancy (geometric mean, 45.4 vs 53.1 nmol/L; 95% confidence interval [CI], 38.6 - 53.4 vs 47.1 - 59.9 nmol/L; P < .01) ... After adjusting for potential confounders, a 50-nmol/L decrease in 25(OH)D concentration was associated with twice the risk for preeclampsia (adjusted odds ratio [OR], 2.4; 95% CI, 1.1 - 5.4). Compared with control newborns, those of women with preeclampsia were twice as likely to have 25(OH)D concentrations less than 37.5 nmol/L" - See vitamin D at Amazon.com.
• Testosterone Reduces Visceral Fat Gain in Nonobese Older Men - Medscape, 2/1/08
• Large Study Links Folic Acid Supplementation With Reduced Risk Of Preeclampsia During Pregnancy - Science Daily, 1/23/08 - "preeclampsia occurred in 2.2 per cent of women who took multivitamins containing folic acid compared to 5.1 per cent of women who did not" - See folic acid at Amazon.com.
• Folic acid supplementation in early second trimester and the risk of preeclampsia - Am J Obstet Gynecol. 2008 Jan;198(1):45.e1-7 - "Supplementation of multivitamins containing folic acid was associated with increased serum folate (on average 10.51 micromol/L), decreased plasma homocysteine (on average 0.39 micromol/L), and reduced risk of preeclampsia (adjusted odds ratio, 0.37; 95% confidence interval, 0.18-0.75)" - See folic acid at Amazon.com.
• Low Vitamin D During Pregnancy Linked To Pre-eclampsia - Science Daily, 9/7/07 - "Low vitamin D early in pregnancy was associated with a five-fold increase in the odds of preeclampsia" - See vitamin D at Amazon.com.
• Maternal Vitamin D Deficiency May Increase Risk for Preeclampsia - Medscape, 6/4/07
• Aspirin Use During Pregnancy Could Reduce Risk Of Pre-Eclampsia - Science Daily, 5/19/07
• Regular Multivitamin Use Near Time of Conception Significantly Reduces Preeclampsia Risk - Doctor's Guide, 7/26/06
• Extra Calcium May Prevent Hypertension Problems in Pregnant Women - Doctor's Guide, 7/21/06 - "Expectant mothers may be able to prevent potentially serious medical problems in themselves and their babies simply by boosting their daily calcium intake"
• A New Way to Reduce Preeclampsia Severity? - Physician's Weekly, 5/15/06
• Vitamins C, E May Not Cut Preeclampsia - WebMD, 4/27/06
• WHO Study Concludes Calcium Supplements Can Reduce Complications During Pregnancy - Doctor's Guide, 3/10/06
• Calcium May Cut Pregnancy Problems - WebMD, 3/10/06
• Vitamins Might Prevent Deadly Pregnancy Condition - CBS 2 Chicago, 7/12/05 - "Recent research suggests large doses of vitamin C and E can prevent preeclampsia"
• Birthing A New Model Of Aspirin Therapy In Preeclampsia - Science Daily, 4/9/05
• Aspirin Reduces Preeclampsia Risk - WebMD, 6/16/03
• Diets High in Vitamin C May Prevent Complication of Pregnancy - New Hope Natural Media, 8/8/02
• Vitamin E 2000 - Nutrition Science News, 3/01
• Aspirin May Ward Off Pregnancy Complication - WebMD, 2/9/01 - "Taking low doses of aspirin could be a good way to prevent dangerously high blood pressure from developing during pregnancy."
• Aspirin Helps Prevent Preeclampsia - Doctor's Guide, 8/25/00
• Moderate Exercise During Pregnancy Lowers Blood Pressure And Reduces Hypertensive Risk - Doctor's Guide, 4/24/00
• Hearts & Bones: Calcium's Many Applications - Nutrition Science News, 2/00

Other News:

• Pre-eclampsia: Early urine test predicts pregnancy complication - Science Daily, 11/19/10
• Simple test can help predict and diagnose preeclampsia - Science Daily, 2/4/10
• Preeclampsia Linked to Reduced Thyroid Function - WebMD, 11/17/09
• Pre-eclampsia May Be Autoimmune Disease - Science Daily, 7/27/08
• Preeclampsia Ups Heart Disease, Death - WebMD, 11/1/07
• Diuretic Pills Not Recommended For Preventing Pre-eclampsia, Report Says - Science Daily, 1/24/07
• Pre-Eclampsia May Increase Risk of Later Kidney Problems in Moms - Doctor's Guide, 1/19/06
• Preeclampsia in Pregnancy Increases Risk of Future Cardiovascular Disease and Death - Doctor's Guide, 4/12/05
• Preeclampsia May Run in Families - WebMD, 4/4/05
• Viagra 'stops pregnancy disorder' - BBC News, 4/4/05
• Urine Test May Predict Preeclampsia Risk - WebMD, 1/4/05
• Preeclampsia May Influence Cancer Risk - WebMD, 3/4/04
• Blood Test May Predict Preeclampsia - WebMD, 2/5/04
• Antithrombin Concentrate May Effectively Treat Severe Preeclampsia - Doctor's Guide, 1/30/04
• Hospital Choice May Help Avoid Cesarean Delivery for Women with Preeclampsia - Doctor's Guide, 12/4/03
• Preeclampsia Predicts Heart Disease - WebMD, 9/5/03
• Hypertension During Pregnancy Heightens Risk Of Later Cardiovascular Problems - Doctor's Guide, 4/17/03
• Pregnancy-Induced Hypertension Raises Later Stroke Risk - WebMD, 4/17/03
• Preeclampsia Ups Risk of Blood Clots - WebMD, 4/10/03
• Future Thromboembolism Risk From Pre-Eclampsia - Doctor's Guide, 4/10/03
• Differences In Blood Pressure Emerge During The First Trimester In Pre-Eclampsia - Doctor's Guide, 3/18/03
• BIDMC Researchers Identify Source Of Preeclampsia - Intelihealth, 3/4/03
• Activin-A And Inhibin-A Significantly Higher In Pre-Eclampsia - Doctor's Guide, 2/26/03
• Coagulation Predicts Pre-Eclampsia Risk - Doctor's Guide, 2/5/03
• Insulin Resistance Increases Gestational Hypertension Risk - Doctor's Guide, 12/24/02
• Transforming Growth Factor-Beta1 Not Related To Hypertension In Pre-Eclampsia - Doctor's Guide, 10/23/02
• Conditioning Factors Identified For Pre-Eclampsia - Doctor's Guide, 10/16/02
• Ambulatory Blood Pressure Test Identifies Risk For Preeclampsia As Early As First Trimester - Doctor's Guide, 9/27/02
• Aspirin Before Bed May Reduce Risk For Preterm Delivery, Gestational Hypertension And Preeclampsia - Doctor's Guide, 9/27/02
• Test Predicts Pregnancy Complication - WebMD, 9/26/02
• Preeclampsia Linked With Higher Risk Of Preterm Delivery - Doctor's Guide, 6/5/02
• Magnesium Sulphate Halves Eclampsia Risk In Pre-Eclampsia Women - Doctor's Guide, 5/30/02
• Safe Drug [magnesium sulfate] Prevents Pregnancy Deaths - WebMD, 5/30/02
• Ten-Year Study Reveals Risk Factors Associated With Preeclampsia - Doctor's Guide, 5/6/02
• Women Who Work During Pregnancy Have Higher Risk of Pre-Eclampsia - Doctor's Guide, 4/17/02
• Simple Blood Test May Reveal Risk of Preeclampsia - Doctor's Guide, 4/4/02
• Early Test for Preeclampsia - WebMD, 4/4/02
• Magnesium Sulfate Does Not Alter Progression of Mild to Severe Pre-eclampsia - Doctor's Guide, 1/22/02
• Risk Of Pre-Eclampsia As Much Paternal As Maternal - Doctor's Guide, 12/31/01
• Hint From a Pregnancy Problem - WebMD, 11/26/01
• Inflammation May Contribute to Pre-eclampsia - Doctor's Guide, 10/3/01
• Calcium Supplementation Does Not Reduce Risk of Preeclampsia - Doctor's Guide, 9/26/01
• Researchers Find Clue To Eclampsia - Intelihealth, 8/31/01
• Incidence Of A Dangerous Complication Of Pregnancy Increases - Intelihealth, 7/10/01
• Possible Cause of Preeclampsia Uncovered, Likely Linked to Low Nitric Oxide Levels in Blood - WebMD, 6/7/01
• Pregnant Pause: Should Expectant Moms Work Into the Third Trimester? Blood Pressure, Risk for Preeclampsia Rise for Pregnant Workers - WebMD, 3/6/01
• High Blood Pressure in Pregnancy May Have Hormonal Culprit - WebMD, 10/17/00
• Link Found Between Snoring During Pregnancy And Hypertension - Doctor's Guide, 1/4/00
• Elevated Cholesterol Linked To Pre-eclampsia - Doctor's Guide, 10/1/99
• Snoring Linked To Pre-eclampsia - Doctor's Guide, 4/27/99
• Researchers Identify Risk Factors For Preeclampsia In Hypertensive Women - Doctor's Guide, 9/3/98
• New Test Predicts Pregnancy Complications Months Before Symptoms Appear - Doctor's Guide, 1/16/98
• Preventing High Blood Pressure In Pregnant Women - Doctor's Guide, 10/31/97