|
|
Home > Health
Conditions > Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis (ALS or Lou Gerhig's Disease)
Alternative News:
-
Gut
microbiome influences ALS outcomes - Science Daily, 5/13/20 -
"mice with a common ALS genetic mutation, changing the
gut microbiome using antibiotics or fecal transplants could prevent or improve
disease symptoms ... he findings provide a potential explanation for why only
some individuals carrying the mutation develop ALS. They also point to a
possible therapeutic approach based on the microbiome ... The gut-brain axis has
been implicated in a range of neurological conditions, including Parkinson's
disease and Alzheimer's disease. Our results add weight to the importance of
this connection" - See probiotic supplements at Amazon.com.
-
Gut
microbes may affect the course of ALS - Science Daily, 7/22/19 -
"To reveal the mechanism by which Akkermansia may be
producing its effect, the scientists examined thousands of small molecules
secreted by the gut microbes. They zeroed in on one molecule called nicotinamide
(NAM): Its levels in the blood and in the cerebrospinal fluid of ALS-prone mice
were reduced following antibiotic treatment and increased after these mice were
supplemented with Akkermansia, which was able to secrete this molecule. To
confirm that NAM was indeed a microbiome-secreted molecule that could hinder the
course of ALS, the scientists continuously infused the ALS-prone mice with NAM.
The clinical condition of these mice improved significantly. A detailed study of
gene expression in their brains suggested that NAM improved the functioning of
their motor neurons" - Note: See previous newsletters.
Akkermansia is the one that may help with weight control.
-
Omega-3s in Diet May Help Ward Off Lou Gehrig's Disease - WebMD, 7/15/14 -
"For the study, Fitzgerald's team looked at the
association between ALS and these fatty acids among almost 1,000 ALS patients
... People ranked in the top 20 percent in terms of their omega-3 fatty acid
intake cut their odds of developing ALS by a third, compared to those in the
bottom 20 percent" - See
fish oil supplements at Amazon.com.
-
Vitamin D
confers protection to motoneurons and is a prognostic factor of amyotrophic
lateral sclerosis - Neurobiol Aging. 2013 Nov 13 -
"Amyotrophic lateral sclerosis (ALS) is an incurable paralytic disorder
primarily typified by the selective and progressive degeneration of motoneurons
in the brain and spinal cord. ALS causes muscle wasting and atrophy, resulting
eventually in respiratory failure and death within 3-5 years of diagnosis.
Vitamin D is a potent secosteroid hormone with diverse biological functions that
include protection against neuronal damage ... Here we found that the
biologically active form of vitamin D significantly potentiated the effect of
neurotrophic factors and prevented motoneurons from a Fas-induced death, while
electrophysiological properties of motoneurons were not affected. In ALS
patients, we report that a severe vitamin D deficiency accelerates by 4 times
the rate of decline and were associated with a marked shorter life expectancy.
Our findings support a neuroprotective function of vitamin D on motoneurons and
propose vitamin D as a reliable prognostic factor of ALS" - See
vitamin D at Amazon.com.
-
Melatonin Delays ALS Symptom Onset and Death in Mice - Science Daily,
4/25/13 - "Melatonin is a naturally occurring hormone
that is best known for its role in sleep regulation. After screening more than a
thousand FDA-approved drugs several years ago, the research team determined that
melatonin is a powerful antioxidant that blocks the release of enzymes that
activate apoptosis, or programmed cell death ... Our experiments show for the
first time that a lack of melatonin and melatonin receptor 1, or MT1, is
associated with the progression of ALS ... We saw similar results in a
Huntington's disease model in an earlier project, suggesting similar biochemical
pathways are disrupted in these challenging neurologic diseases" - See
melatonin at Amazon.com.
-
Eating
Bright-Colored Fruits and Vegetables May Prevent or Delay Amyotrophic Lateral
Sclerosis - Science Daily, 1/29/13 - "Using data
from five prospective groups: the National Institutes of Health (NIH)–AARP Diet
and Health Study, the Cancer Prevention Study II-Nutrition Cohort, the
Multiethnic Cohort, the Health Professionals Follow-up Study, and the Nurses’
Health Study, researchers investigated more than one million participants for
the present study ... subjects with diets high in beta-carotene and lutein—found
in dark green vegetables—had a lower risk ALS risk" - See
Jarrow Formulas, CarotenALL at Amazon.com.
-
Lithium
profoundly prevents brain damage associated with Parkinson's disease, mouse
study suggests - Science Daily, 6/24/11 - "lithium
has recently been suggested to be neuroprotective in relation to several
neurodegenerative conditions including Alzheimer's disease, Huntington's disease
and amyotrophic lateral sclerosis and has been touted for its anti-aging
properties in simple animals" - See lithium supplements at Amazon.com.
-
Long-Term Vitamin E Intake Linked to Reduced ALS Risk - Medscape,
3/29/11 -
"For dietary vitamin E intake, the adjusted RR
comparing the highest quartile with the lowest was 0.79" - See
Jarrow FamilE (contains all eight members of the vitamin E family, includes
Tocomin) at Amazon.com.
-
High
Polyunsaturated Fat And Vitamin E Intake May Halve Motor Neurone Disease
Risk - Science Daily, 4/30/06
-
Diet May Slow Lou
Gehrig's Disease - WebMD, 4/21/06
- Lou Gehrig's
Disease Not treatable With Creatine - WebMD, 3/24/03
-
Fat Abnormalities Hold Gehrig's Clue - Intelihealth, 9/16/02 -
"Free radicals have long been thought to play a role
in ALS, and some ALS specialists advise taking
antioxidant vitamins in hopes of curbing them. In Mattson's experiment,
published in this month's Annals of Neurology, free radicals caused
ceramides to rise inside those crucial nerve cells ... Indeed, doctors like
Newman expect medications, not diet, to ultimately hold the key. For now,
Newman advises patients just to eat the moderate-fat diet the government
already recommends for a healthy heart and take antioxidants such as
vitamin E
as a precaution"
-
DA Grants Orphan Drug Status to Creatine for Amyotrophic Lateral Sclerosis
- Doctor's Guide, 3/26/02 -
"Creatine
is a critical element in cellular energy production and modulation. It is the
substrate of the creatine kinase system, which helps prolong cellular life
and protect against cell injury and death ... We have seen, and continue to
see, encouraging results among ALS patients, as measured by muscle strength
and a decreased rate of deterioration. Additionally, creatine has a long
history of safe use, and is well tolerated by patients in the study"
News & Research:
-
Ultra-High Dose Drug Slows
Functional Decline in Early ALS, Phase 3 Data Show - Medscape, 5/12/22 -
"Methylcobalamin, an active form of vitamin B12
analogue, helps eliminate homocysteine, which is neurotoxic and induces
oxidative stress, mitochondrial dysfunction, inflammation, and motor neuron
death. Plasma homocysteine levels are reported to be elevated in patients with
ALS ... In the 90% of patients taking riluzole concomitantly, the difference in
favor of methylcobalamin was even greater (–2.11 ... The results suggest that
riluzole and ultrahigh-dose methylcobalamin not only have an additive but
possibly also a synergistic effect"
-
Pesticide exposure contributes to faster ALS progression - Science Daily,
2/28/19 - "While exact causes of amyotrophic lateral
sclerosis (ALS) remain unknown, new research shows pesticides and other
environmental pollutants advance the progression of the neurodegenerativedisease"
- Note: There is always some new guy in our neighborhood asking what to do
about ants. Most people recommend a specific exterminator. My
response is always 'Terro' which is made with borax because I worry about things
like ALS and Parkinson's. I put them the
large size around the
outside and inside of the house in the spring. The ants bring it back to
their nest and it kills the queen ant.
-
Letter of Recommendation: Terro Liquid Ant Bait - NYT,
12/31/15 - "But one thing seems to: Terro Liquid Ant Bait.
This is not your usual trap — those black plastic ant yurts
no self-respecting ant would ever enter. Terro comes in a
plastic rectangle with two compartments, which together make
up a minimalist slaughterhouse. One side is filled with a
syrupy liquid, a sugar solution with borax. The other forms
a small ramp leading into the solution"
-
Getting to the Bottom of Borax: Is it Safe or Not? -
crunchybetty.com, 1/8/19 - "Not one
single natural ingredient has me quite as verklempt as
borax"
-
ALS
clinics start implanting breathing-assist device under new FDA approval
- Science Daily, 5/2/12
-
Common cause of all forms of amyotrophic lateral sclerosis (ALS) discovered
- Science Daily, 8/21/11
-
Compound Shows Potential For Slowing Progression Of Lou Gehrig's Disease
- Science Daily, 10/19/09
-
New Guidelines for ALS Treatment - WebMD, 10/12/09
-
Caffeine Appears To Be Beneficial In Males, But Not Females, With Lou
Gehrig's Disease - Science Daily, 4/17/09
-
Spinal Fluid Proteins Signal Lou Gehrig's Disease - Science Daily,
1/28/09
-
Umbilical Cord Blood Cell Transplants May Help ALS Patients - Science
Daily, 6/25/08
-
Lou
Gehrig's Protein Found Throughout Brain, Suggesting Effects Beyond Motor
Neurons - Science Daily, 6/16/08
-
Chemical Exposure May Increase Risk Of ALS, Study Shows - Science Daily,
4/17/08
-
ALS Drug Slows Melanoma Growth - WebMD, 4/15/08
-
Targeting Astrocytes Slows Disease Progression In Lou Gehrig's Disease,
Study Shows - Science Daily, 2/3/08
-
Protein Injections Can Delay Symptoms Of Lou Gehrig's Disease - Science
Daily, 11/27/07
-
Discovery Offers Hope Of Halting Amyotrophoic Lateral Sclerosis Progression
- Science Daily, 10/4/07
-
New
Insight Into Cause Of Lou Gehrig's Disease - Science Daily, 5/29/07
-
High
Caloric Diet May Prevent Progression Of Amyotrophic Lateral Sclerosis (ALS)
- Doctor's Guide, 4/18/06
-
Cognitive Impairment Appears to Be Common in ALS Patients - Doctor's
Guide, 3/17/06
-
Thalidomide for Lou Gehrig's Disease? - WebMD, 3/16/06
-
First Diagnostic Indicator For Amytrophic Lateral Sclerosis (ALS) Identified
- Science Daily, 2/23/06
-
Exercise Plus Gene Therapy Shows Promise For Treating Lou Gehrig's Disease
- Science Daily, 11/14/05
-
Sticky Mutant Proteins Implicated In Lou Gehrig's Disease - Science
Daily, 8/17/05
- No Link Between
Athleticism and ALS - WebMD, 1/25/05
-
Promising Results In The Battle Against Incurable ALS Muscle Disease -
Science Daily, 11/30/04
-
New Hope For ALS Seen With Genetic Techniques, Growth Factors - Science
Daily, 11/2/04
- Gastrostomy Tube
System Helpful for Patients With ALS - Medscape, 10/27/04
-
Olfactory Bulb Stem Cells And Lou Gehrig's Disease - Science Daily,
10/27/04
-
Nerve Cells' Powerhouse "Clogged" In Lou Gehrig's Disease - Science
Daily, 7/19/04
- Veterans Face
Higher Risk of ALS - Doctor's Guide, 4/28/04
- Gene Linked to
Lou Gehrig's Disease - WebMD, 7/8/03
- Genes,
Environment Linked to ALS - WebMD, 4/21/03
- Progress in Lou
Gehrig's Disease - WebMD, 1/24/02 -
"the antibiotic minocycline helps fight several
brain diseases -- including ALS. Meanwhile, another group showed that the
dietary supplement creatine also helps fight
these kinds of diseases ... We combined the two and showed that together
they are both more effective than either alone in the treatment of ALS"
- Arthritis Drug
[Celebrex] Slows ALS in Mice - WebMD, 9/25/02
- Athletes and Lou
Gehrig's Disease - WebMD, 9/9/02
-
Riluzole Influences Amino Acid Metabolism In Advanced Amyotrophic Lateral
Sclerosis Neural Tissue - Doctor's Guide, 7/11/02
-
Amyotrophic Lateral Sclerosis Patients Ask Doctors For Suicide Help -
Doctor's Guide, 5/23/02
-
Predictors Of Amyotrophic Lateral Sclerosis Progression Still Unclear -
Doctor's Guide, 5/13/02
-
Antibiotic May Slow Gehrig's Disease - Intelihealth, 5/6/02
-
Cortical Reorganization In Amyotrophic Lateral Sclerosis Patients -
Doctor's Guide, 4/8/02
-
Imaging Technique May Aid In Amyotrophic Lateral Sclerosis - Doctor's
Guide, 4/3/02
-
Higher Sympathetic Activity In Amyotrophic Lateral Sclerosis - Doctor's
Guide, 3/5/02
- Feds Acknowledge
Lou Gehrig's Disease a Gulf War Illness - WebMD, 12/11/01
Related Searches:
71120
|
|