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Alternative News:

• Immunotherapeutic potential of ethanolic olive leaves extract (EOLE) and IL-28B combination therapy in ENU induced animal model of leukemia - Cytokine 2022 May 28 - "the combination of EOLE and IL-28B has given substantial therapeutic activity against leukemia" - See olive leaf extract at Amazon.com.
• Involvement of Sphingolipid Metabolism Enzymes in Resveratrol-Mediated Cytotoxicity in Philadelphia-Positive Acute Lymphoblastic Leukemia - Nutr Cancer 2021 Nov 22 - "Targeting the key enzymes of sphingolipid metabolism including serine palmitoyltransferase (SPT), sphingosine kinase (SK) and glucosylceramide synthase (GCS) has a therapeutic importance. However, sphingolipid metabolism-mediated anti-leukemic actions of resveratrol in Philadelphia-positive acute lymphoblastic leukemia (Ph + ALL) remain unknown ... Resveratrol inhibited proliferation and triggered apoptosis via PARP activation and externalization of phosphatidylserine (PS). Resveratrol increased the expression of SPT whereas it downregulated SK and GCS. Resveratrol's combinations with SKI II and PDMP intensified its anti-leukemic activity by increasing the relocalization of PS while its combination with myriocin suppressed apoptosis. Therefore, resveratrol inhibited cell proliferation and induced apoptosis through modulating SK, GCS and SPT expression, which may be considered as novel biomarkers of resveratrol-induced cytotoxicity in Ph + ALL" - See resveratrol products at Amazon.com.
• Avocado discovery may point to leukemia treatment - Science Daily, 4/29/21 - "Earlier, his lab looked at avocatin B, a fat molecule found only in avocados, for potential use in preventing diabetes and managing obesity. Now he's eager to see it used in leukemia patients"
• Vitamin D levels in patients with non-Hodgkin lymphoma/diffuse large B-cell lymphoma, chronic lymphocytic leukemia and multiple myeloma - J Int Med Res 2020 Jul - "We measured serum levels of vitamin D by ELISA in 103 patients prior to initiation of treatment, of whom 37 were diagnosed with MM, 32 with CLL and 34 with NHL-DLBCL ... Suboptimal serum vitamin D levels (<30 ng/mL) were observed in all 103 patients. In 14 patients, serum vitamin D levels were between 20 and 30 ng/mL, while all other patients had vitamin D deficiency (<20 ng/mL). Severe vitamin D deficiency (<10 ng/mL) was observed in 32.3% of NHL-DLBCL patients, 28.1% of CLL patients and 81% of MM patients" - See vitamin D at Amazon.com and vitamin D at iHerb.
• The Role of the Curcumin for Inducing Apoptosis in Acute Lymphoblastic Leukemia Cells: A Systematic Review - Nutr Cancer 2020 Jul 13 - "Acute lymphoblastic leukemia (ALL) is a hematological malignancy of lymphoid progenitor cells associated with excessive proliferation of lymphocytes. Curcumin, a polyphenolic compound, is known to possess anticancer activity ... According to six articles that were selected, curcumin could enhance the antitumor activity of chemotherapy drugs such as L-asparaginase. Curcumin induces apoptosis in Pre B- ALL and T- ALL cells by decreased NF-kB levels, increased p53 levels, PARP-1 cleavage. Also, the induction of growth-arrest and apoptosis in association with the blockade of constitutively active JAK-STAT pathway suggests this be a mechanism by curcumin. Curcumin could be used for the treatment of cancer like ALL" - See curcumin at Amazon.com and iHerb.
• Melatonin inhibits MLL-rearranged leukemia via RBFOX3/hTERT and NF-κB/COX-2 signaling pathways - Cancer Lett. 2018 Dec 11;443:167-178 - "MLL-rearranged leukemia is an aggressive malignancy associated with poor outcome, which is refractory to conventional treatment. Melatonin has been proven to exert anti-tumor activity ... Collectively, these results suggest that melatonin inhibits MLL-rearranged leukemia through suppressing the RBFOX3/hTERT and NF-κB/COX-2 signaling pathways. Our findings provide new insights into the role of melatonin for MLL-r leukemia treatment" - See melatonin at Amazon.com.
• L-Ascorbic Acid and α-Tocopherol Reduces Hepatotoxicity Associated with Arsenic Trioxide Chemotherapy by Modulating Nrf2 and Bcl2 Transcription Factors in Chang liver Cells - Nutr Cancer. 2018 Apr 26:1-13 - "Arsenic trioxide (As2O3) is a promising new regimen for the treatment of acute promyelocytic leukemia (APL). The induction of oxidative stress mediated by reactive oxygen species (ROS) and excessive intracellular calcium influx are the main reasons behind As2O3 toxicity ... Cotreatment of antioxidant vitamins with As2O3 resulted in a significant reversal of oxidative stress markers. Our findings substantiate the effect of antioxidant vitamins in protecting the hepatocytes from oxidative stress which may be attributed through Nrf2 (Nuclear factor erythroid 2-related factor 2) mediated upregulation of Bcl2 (B-cell lymphoma 2) expression" - See vitamin C products at Amazon.com and vitamin E products at Amazon.com.
• Vitamin C regulates stem cell function, curbs leukemia development, scientists discover - Science Daily, 8/21/17 - "These findings have implications for older patients with a common precancerous condition known as clonal hematopoiesis. This condition puts patients at a higher risk of developing leukemia and other diseases, but it is not well understood why certain patients with the condition develop leukemia and others do not ... Our results suggest patients with clonal hematopoiesis and a Tet2 mutation should be particularly careful to get 100 percent of their daily vitamin C requirement ... Because these patients only have one good copy of Tet2 left, they need to maximize the residual Tet2 tumor-suppressor activity to protect themselves from cancer" - See American Health Products - Ester C W/Citrus Bioflavonoids, 1000 mg, 180 veg tablets at Amazon.com.
• Vitamin C may encourage blood cancer stem cells to die - Science Daily, 8/17/17 - "Vitamin C may "tell" faulty stem cells in the bone marrow to mature and die normally, instead of multiplying to cause blood cancers ... We're excited by the prospect that high-dose vitamin C might become a safe treatment for blood diseases caused by TET2-deficient leukemia stem cells, most likely in combination with other targeted therapies ... Changes in the genetic code (mutations) that reduce TET2 function are found in 10 percent of patients with acute myeloid leukemia (AML), 30 percent of those with a form of pre-leukemia called myelodysplastic syndrome, and in nearly 50 percent of patients with chronic myelomonocytic leukemia ... vitamin C did the same thing as restoring TET2 function genetically. By promoting DNA demethylation, high-dose vitamin C treatment induced stem cells to mature, and also suppressed the growth of leukemia cancer stem cells from human patients implanted in mice" - See American Health Products - Ester C W/Citrus Bioflavonoids, 1000 mg, 180 veg tablets at Amazon.com.
• Higher risk of leukemia linked to low sunlight, vitamin D - Science Daily, 1/6/16 - "These results suggest that much of the burden of leukemia worldwide is due to the epidemic of vitamin D deficiency we are experiencing in winter in populations distant from the equator" - See vitamin D at Amazon.com.
• Could Common Diabetes Drugs Help Fight Leukemia? - WebMD, 9/2/15 - "patients with chronic myeloid leukemia (CML) who received a glitazone -- a class of drug for type 2 diabetes -- along with the standard CML drug imatinib remained disease-free for up to nearly five years ... Actos and Avandia are two well-known glitazone"
• Chemopreventive effects of dietary eicosapentaenoic acid supplementation in an experimental myeloid leukemia - Cancer Prev Res (Phila). 2015 Aug 19 - "Supplemented mice exhibited a decrease in leukemia burden and a decrease in the LSC colony-forming unit (LSC-CFU). The decrease in LSCs was confirmed through serial transplantation assays in all disease models. The results support a chemopreventive role for EPA in myeloid leukemia, which is dependent on the ability to efficiently convert EPA to endogenous cyclooxygenase-derived prostanoids, including Δ12-PGJ3" - See fish oil supplements at Amazon.com.
• Korean Red Ginseng Extract Enhances the Anticancer Effects of Imatinib Mesylate Through Abrogation p38 and STAT5 Activation in KBM-5 Cells - Phytother Res. 2015 Apr 8 - "Although imatinib mesylate (IM) in the treatment of chronic myelogenous leukemia (CML) remains the best example of successful targeted therapy, majority of patients with CML suffer its toxicity profile and develop chemoresistance to existing therapeutic agents ... Korean red ginseng extract broadly suppressed the proliferation of five different cell lines, but KRGE was found to be the most potent inducer of apoptosis against KBM-5 cells ... The combination treatment of KRGE and IM caused pronounced suppression of p38 and signal transducer and activator of transcription 5 phosphorylation and induced phosphorylation of p53 compared with the individual treatment. Our results demonstrate that KRGE can enhance the anticancer activity of IM and may have a substantial potential in the treatment of CML" - See ginseng at Amazon.com.
• Multi-target effects of Quercetin in Leukemia - Cancer Prev Res (Phila). 2014 Oct 7 - "The antitumor activity of quercetin both in vitro and in vivo revealed in this study, point to quercetin as an attractive antitumor agent for hematological malignancies" - See quercetin at Amazon.com.
• The Protective Role of Resveratrol against Arsenic Trioxide-Induced Cardiotoxicity - Evid Based Complement Alternat Med. 2013;2013:407839 - "Arsenic trioxide (As2O3) shows substantial anticancer activity in patients with acute promyelocytic leukemia (APL). Unfortunately, limiting the application of this effective agent to APL patients is severe cardiotoxicity. Resveratrol, the natural food-derived polyphenolic compound, is well known for its antioxidant properties and protects the cardiovascular system. But the potential role of resveratrol against As2O3 in heart via nuclear factor erythroid 2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1) is unclear ... Our findings suggest coadministration with resveratrol, and As2O3 might provide a novel therapeutic strategy for APL" - See resveratrol products at Amazon.com.
• Dietary Intake of Vegetables, Fruits, and Meats/Beans as Potential Risk Factors of Acute Myeloid Leukemia: A Texas Case-Control Study - Nutr Cancer. 2013 Oct 29 - "This study was conducted at the University of Texas MD Anderson Cancer Center to evaluate associations between consumption of vegetables, fruits, and meats with AML risk among Texas residents ... Overall, AML risk was significantly decreased among those who consumed the most dark green vegetables, seafood, and nuts/seeds; and it was significantly increased among greatest consumers of red meat. Among men, AML risk was lowest among those whose consumption was in the highest quartile for fruits [odds ratio (OR) = 0.25, 95% confidence interval (CI) = 0.10-0.69], poultry (OR = 0.28, 95%CI = 0.10-0.78), and seafood (OR = 0.39, 95%CI = 0.16-0.96) compared to those in the lowest. Among women, risk was lowest among those whose consumption was in the highest quartile of dark-green vegetables (OR = 0.28, 95%CI = 0.12-.68), orange vegetables (OR = 0.40, 95%CI = 0.17-.96) and nuts/beans (OR = 0.26, 95%CI = 0.11-0.60)"
• Zinc supplementation in children and adolescents with acute leukemia - Eur J Clin Nutr. 2013 Aug 21 - "The aim of this study was to evaluate the effects of oral zinc supplementation on weight gain and infectious episodes in children and adolescents with acute leukemia ... study included 38 patients ... it has become evident that supplementary zinc exerts a positive effect on nutritional status as positive weight gain. Moreover, the number of infection episodes was significantly reduced, possibly because of the immune stimuli ... zinc supplementation can prevent some of the chemotherapy adverse effects in children with leukemia, improving their quality of life" - See Jarrow Zinc Balance at Amazon.com.
• Vegetable compound could become ingredient to treating leukemia - Science Daily, 12/12/12 - "A concentrated form of a compound called sulforaphane found in broccoli and other cruciferous vegetables has been shown to reduce the number of acute lymphoblastic leukemia cells in the lab setting ... performed this work while a clinical fellow in the Texas Children's Cancer and Hematology Centers, incubated human-derived leukemic cell lines and primary lymphoblasts from pediatric patients with the compound. The cancer cells died while the healthy cells obtained from healthy donors were unaffected. Studies tested in pre-clinical mouse models showed similar results" - See sulforaphane at Amazon.com.
• Neoplasm Prevention and Immuno-Enhancement Mediated by Daily Consumption of a Proprietary Extract from North American Ginseng by Elderly Mice of a Cancer-Prone Strain - Phytother Res. 2012 Nov 7 - "We have previously shown in a leukemia-induced tumor model (mouse) that a proprietary extract (CVT-E002), of North American ginseng, administered in the diet, significantly increased the absolute numbers of NK cells, significantly decreased leukemia cells and significantly increased the life span of CVT-E002-fed leukemic mice. In the present study, we assessed the efficacy of this extract to inhibit the spontaneous development of tumors in elderly mice of the cancer-prone C3H strain. Dietary CVT-E002 was fed for approximately a year beginning when mice were almost 2 years of age. Control mice, consuming the same chow without CVT-E002, all developed assorted, palpable tumors between 22 and 33 months, while all mice consuming CVT-E002 remained alive and tumor-free until they were purposely euthanized as healthy animals. The absolute numbers of NK cells at euthanasia, in CVT-E002-consuming mice, were significantly elevated in both the spleen and bone marrow. Given these profoundly positive results and the fact that CVT-E002 already exists in the marketplace under the label Cold-fX®, the potential for cancer prevention in humans becomes apparent" - See Cold FX, 300mg 168 Capsules.
• Possible cure for leukemia found in fish oil - Science Daily, 12/22/11 - "The compound -- delta-12-protaglandin J3, or D12-PGJ3 -- targeted and killed the stem cells of chronic myelogenous leukemia, or CML, in mice ... The compound is produced from EPA -- Eicosapentaenoic Acid -- an Omega-3 fatty acid found in fish and in fish oil ... During the experiments, the researchers injected each mouse with about 600 nanograms of D12-PGJ3 each day for a week. Tests showed that the mice were completely cured of the disease. The blood count was normal, and the spleen returned to normal size. The disease did not relapse ... The researchers focused on D12-PGJ3 because it killed the leukemia stem cells, but had the least number of side effects" - See Mega Twin EPA at Amazon.com.
• Resveratrol enhances the expression of death receptor Fas/CD95 and induces differentiation and apoptosis in anaplastic large-cell lymphoma cells - Cancer Lett. 2011 Jun 15 - "Resveratrol inhibited growth and induced cellular differentiation, as demonstrated by morphological changes and elevated expression of T cell differentiation markers CD2, CD3, and CD8. Resveratrol also triggered cellular apoptosis, as demonstrated by morphological observations, DNA fragmentation, and cell cycle analyses. Further, the surface expression of the death receptor Fas/CD95 was increased by resveratrol treatment. Our data suggest that resveratrol may have potential therapeutic value for ALCL" - See resveratrol products at Amazon.com.
• Resveratrol Triggers Apoptosis Through Regulating Ceramide Metabolizing Genes in Human K562 Chronic Myeloid Leukemia Cells - Nutr Cancer. 2011 Apr 14:1 - "There were synergistic cytotoxic and apoptotic effects of resveratrol with coadministration of C8:ceramide, PDMP, and SK-1 inhibitor. Interestingly, there were also significant increases in expression levels of LASS genes and decreases in expression levels of GCS and SK-1 in K562 cells in response to resveratrol. Our data, in total, showed for the first time that resveratrol might kill CML cells through increasing intracellular generation and accumulation of apoptotic ceramides" - See resveratrol products at Amazon.com.
• Insufficient vitamin D levels in chronic lymphocytic leukemia patients linked to cancer progression and death - Science Daily, 11/3/10 - "patients with insufficient levels of vitamin D when their leukemia was diagnosed progressed much faster and were about twice as likely to die as were patients with adequate levels of vitamin D ... They also found solid trends: increasing vitamin D levels across patients matched longer survival times and decreasing levels matched shortening intervals between diagnosis and cancer progression ... Other studies have suggested that low vitamin D levels at diagnosis may be associated with poorer outcomes in colorectal, breast, melanoma and lung cancers, as well as lymphoma ... Vitamin D insufficiency, in general, is widespread" - See vitamin D at Amazon.com.
• Green tea extract appears to keep cancer in check in majority of CLL patients - Science Daily, 6/4/10 - "the blood lymphocyte (leukemia cell) count was reduced in one-third of participants, and that the majority of patients who entered the study with enlarged lymph nodes due to involvement by CLL saw a 50 percent or greater reduction in their lymph node size ... 31 percent of patients had a 20 percent or greater sustained reduction in blood leukemia count, and 69 percent of patients with enlarged lymph nodes saw a reduction of node size of 50 percent or greater" - It says 6/4/10 but it just showed up.  I think it's a misprint.  See green tea extract at Amazon.com.
• Exercise Benefits Leukemia Patients - Science Daily, 8/3/09
• Green tea may protect against blood cell cancer - Nutra USA, 7/31/09 - "Drinking five or more cups of green tea per day may reduce the risk of blood- and lymph-based cancers by about 50 per cent ... Compared to people who drank only one cup per day, five cups of green tea a day were associated with a 42 per cent reduction in hematologic malignancies, and a 48 per cent risk reduction in lymphoid neoplasms" - [Abstract] - See green tea extract at Amazon.com.
• Green Tea Consumption and Hematologic Malignancies in Japan: The Ohsaki Study - Am J Epidemiol. 2009 Jul 29 - "Risk of hematologic malignancies was inversely associated with green tea consumption. The multivariate-adjusted hazard ratio of hematologic malignancies for 5 cups/day or more compared with less than 1 cup/day of green tea was 0.58 (95% confidence interval: 0.37, 0.89). The corresponding risk estimate was 0.52 (95% confidence interval: 0.31, 0.87) for lymphoid neoplasms and 0.76 (95% confidence interval: 0.32, 1.78) for myeloid neoplasms" - See green tea extract at Amazon.com.
• Green Tea Extract Shows Promise In Leukemia Trials - Science Daily, 5/26/09 - "We found not only that patients tolerated the green tea extract at very high doses, but that many of them saw regression to some degree of their chronic lymphocytic leukemia ... majority of individuals who entered the study with enlarged lymph nodes saw a 50 percent or greater decline in their lymph node size" - See green tea extract at Amazon.com.
• Grape-seed Extract Kills Laboratory Leukemia Cells, Proving Value Of Natural Compounds - Science Daily, 12/31/08 - "An extract from grape seeds forces laboratory leukemia cells to commit cell suicide, according to researchers from the University of Kentucky. They found that within 24 hours, 76 percent of leukemia cells had died after being exposed to the extract ... They also discovered that the extract does not affect normal cells, although they don't know why" - See grape seed extract at Amazon.com.
• Vitamin D3 induces autophagy of human myeloid leukemia cells - J Biol Chem. 2008 Jul 15 - "These findings extend our understanding of the action of vitamin D3 in antineoplastic effects and the role of Beclin1 in regulating multiple cellular cascades, and suggest a potentially promising strategy with a significantly better antileukemia effect" - See vitamin D at Amazon.com.
• Molecular mechanisms of mistletoe plant extract-induced apoptosis in acute lymphoblastic leukemia in vivo and in vitro - Cancer Lett. 2008 Feb 29 - "Aqueous mistletoe extracts (MT) ... Both MTs significantly improved survival (up to 55.4 days) at all tested concentrations in contrast to controls (34.6 days) without side effects"
• Antioxidant Found In Many Foods And Red Wine Is Potent And Selective Killer Of Leukemia Cells - Science Daily, 4/23/07 - "anthocyanidins, a group of naturally occurring compounds widely available in fruits and vegetables as well as red wine, have chemopreventive properties ... the most common type of a naturally modified anthocyanidin, known as cyanidin-3-rutinoside, or C-3-R ... C-3-R caused about 50 percent of a human leukemia cell line known as HL-60 to undergo programmed cell death"
• Mayo Clinic Reports Some Chronic Leukemia Patients May Improve By Taking An Extract Of Green Tea - Science Daily, 12/13/05 - "In the small case study, the researchers report on four patients who appeared to have an improvement in the clinical state of their disease after starting over-the-counter products containing epigallocatechin gallate (EGCG), an extract of green tea. Three of the four patients met the standard criteria used to define a response treatment for clinical trials. These same investigators had previously shown that EGCG kills leukemia cells from patients with CLL in the test tube" - See iHerb or Vitacost green tea products.
• Leukemia and Lymphoma (Hodgkin's and Non-Hodgkin's Disease) - Life Extension Foundation
• Tea Ingredient Fights Leukemia - WebMD, 4/4/05 - "Tea extracts shut down leukemia cells but help normal cells fight cancer and infection" - See iHerb or Vitacost green tea products.
• Chemical in Feverfew Plant May Fight Leukemia - WebMD, 2/25/05
• Can A Daisy Kill Leukemia? - mercola.com, 2/24/05
• Child's leukaemia risk lower if mother eats well - Nutra USA, 9/28/04
• Many Children With ALL Deficient in Antioxidant Vitamins - Medscape, 6/7/04
• VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia - Blood. 2004 Aug 1;104(3):788-94
• Green tea action on leukaemia - Nutra USA, 4/1/04
• Aspirin Reduces Risk of Leukemia by Half - Physician's Weekly, 8/4/03 - "women who took aspirin two or more times per week were 55% less likely to develop leukemia than those who never used aspirin" - See aspirin at Amazon.com.
• Aspirin May Lower Adult Leukemia Risk - WebMD, 6/17/03
• Pregnancy Vitamins Cut Leukemia in Kids - WebMD, 12/6/01 - "Moms who used both folic acid and iron supplements in pregnancy were 60% less likely to have a child develop leukemia"
• Proanthocyanidin Power - Nutrition Science News, 6/00
• Cancer Prevention Diet - Nutrition Science News, 8/99
• Immune Enhancers - Nutrition Science News, 2/99

Other News:

• 93 percent of advanced leukemia patients in remission after immunotherapy - Science Daily, 4/27/16
• New drug combination therapy developed to treat leukemia - Science Daily, 4/17/13
• FDA Approves Synribo for Drug-Resistant Leukemia - WebMD, 10/29/12
• Promising treatments for blood cancers - Science Daily, 12/22/11
• New leukemia treatment exceeds 'wildest expectations' - MSNBC, 8/10/11
• Chlorine and childhood cancer - Science Daily, 5/25/11 - "A significant positive association between the risk of childhood leukemia and levels of chlorine-containing chemicals in the atmosphere has been found by researchers in Portugal ... potential emissions from paper-related industry, forest fires, pesticides manufacturing, heavy chemical industry and fossil fuel power stations may lead to higher levels of chlorine-containing carcinogens in the air ... lichens have been used as accurate biomarkers of pollution levels since the 1970s. Lichens are excellent biomonitors because they depend largely on atmospheric depositions for their nutrient supply, thus showing elemental compositions which reflect the gaseous, dissolved and/or particulate elements in the atmosphere, the team explains"
• New approach to leukemia chemotherapy -- is a cure in sight? - Science Daily, 3/30/11
• Antibody-directed chemotherapy offers improved survival for some leukemia patients - Science Daily, 2/22/11
• Early life exposure to infections and risk of childhood acute lymphoblastic leukemia - Int J Cancer. 2011 Apr 1;128(7):1632-43 - "exposure to common infections early in life may be protective against childhood acute lymphoblastic leukemia (ALL) ... daycare attendance by the age of 6 months (odds ratio [OR] for each thousand child-hours of exposure = 0.90, 95% confidence interval [CI]: 0.82-1.00) and birth order (OR for having an older sibling = 0.68, 95% CI: 0.50-0.92) were associated with a reduced risk of ALL among non-Hispanic white children but not Hispanic children, whereas ear infection before age 6 months was protective in both ethnic groups. When the three measures were assessed simultaneously, the influence of daycare attendance (OR = 0.83, 95% CI: 0.73-0.94) and having an older sibling (OR = 0.59, 95% CI: 0.43-0.83) became stronger for non-Hispanic white children. In Hispanic children, a strong reduction in risk associated with ear infections persisted (OR = 0.45, 95% CI: 0.25-0.79). Evidence of a protective role for infection-related exposures early in life is supported by findings in both the non-Hispanic white and Hispanic populations within the NCCLS"
• New cancer treatment gives hope to lymphoma and leukemia patients - Science Daily, 2/26/10
• Stem Cell Treatment for Leukemia Improved - WebMD, 1/19/10
• Funeral industry workers exposed to formaldehyde face higher risk of leukemia - Science Daily, 11/23/09
• New Drug For Children With High-risk Leukemia - Science Daily, 7/28/09
• New Treatment Avenue For Acute Myeloid Leukemia? - Science Daily, 7/6/09
• New Targeted Therapy Finds And Eliminates Deadly Leukemia Stem Cells - Science Daily, 7/2/09
• Leukemia can be cured without brain damage - USATODAY.com, 6/25/09
• Lethal Cancer Knocked Down By One-two Drug Punch - Science Daily, 6/7/09
• New Biomarker May Predict Leukemia Aggressiveness - Science Daily, 4/19/09
• Enhancing Effects Of Drug Used To Treat Chronic Myeloid Leukemia - Science Daily, 4/13/09
• Triple Therapy: New Standard for CLL? - OncologySTAT, 12/8/08
• New Drug Combination Kills Leukemia Cells By Shutting Down Their Energy Source - Science Daily, 5/16/08
• Daycare Attendance Early In Life Cuts Childhood Leukemia Risk By 30 Percent, Analysis Finds - Science Daily, 4/28/08
• Kidney Cancer Drug Attacks A Major Type Of Acute Myeloid Leukemia - Science Daily, 1/29/08
• New Drug Candidate Knocks Out Resistant Form Of Chronic Myeloid Leukemia - Science Daily, 1/2/08
• New Leukemia Vaccine May Prolong Life - WebMD, 12/10/07
• Anti-leukemia Drug Increases Patient Fatigue - Science Daily, 11/20/07
• Leukemia Drug Proves Safe and Effective Over the Long Term - Doctor's Guide, 11/8/07
• Anti-Leukemia Drug Increases Patient Fatigue - Doctor's Guide, 11/2/07
• Tasigna® (Nilotinib) Receives U.S. Approval for Chronic Myeloid Leukemia in Patients With Resistance or Intolerance to Existing Therapies - Doctor's Guide, 10/30/07
• FDA OKs Novartis leukemia drug - USATODAY.com, 10/29/07
• Drug Has Ability To Cure Type Of Leukemia - Science Daily, 10/2/07
• New Combination Treatment For Chronic Lymphocytic Leukaemia Increases Progression-Free Survival And Response, Study Suggests - Science Daily, 7/22/07
• New Treatment Protocol Increases Survival Of Very Young Infants With Acute Lymphoblastic Leukemia - Science Daily, 7/22/07
• Drug Combo Effective Against Leukemia - WebMD, 7/19/07
• Dasatinib Shows High Early Response Rate as First Treatment for Chronic Myelogenous Leukemia - Doctor's Guide, 6/12/07
• Lymphocyte Count Found To Be A Predictor Of Survival For Young Patients With Leukemia - Science Daily, 5/7/07
• Childhood Leukemia Increases Risk of More Cancer - WebMD, 3/20/07
• New Line Of Treatment Discovered For Acute Lymphoblastic Leukemia - Science Daily, 2/13/07
• Patients on Imatinib Achieve Complete Response With Continued Treatment - Doctor's Guide, 12/13/06
• Fighting Leukemia: Regimen Of Three Chemotherapy Drugs Shows Promise - Science Daily, 12/11/06
• Imatinib Mesylate Demonstrates Highest Five-Year Overall Survival Rate in History of Treatment for Patients With Chronic Myeloid Leukemia - Doctor's Guide, 12/7/06
• Dacogen(TM) (Decitabine) for Injection Receives U.S. Orphan Drug Designation for Patients With Acute Myeloid Leukemia - Doctor's Guide, 8/10/06
• FDA Expands Use for Leukemia Drug - WebMD, 7/26/06
• FDA Approves Oncaspar for Newly-Diagnosed Acute Lymphoblastic Leukemia - Doctor's Guide, 7/25/06
• FDA Approves Sprycel (Dasatinib) With Two Indications - Doctor's Guide, 6/29/06
• Drug Offers New Options For Leukemia Patients - Science Daily, 6/19/06
• Dasatinib Shows Greater Efficacy Than Very High-Dose Imatinib for Imatinib-Resistant Chronic-Phase Myelogenous Leukemia (CML) Patients - Doctor's Guide, 6/5/06
• Dasatinib Controls Chronic Myelogenous Leukemia in Gleevec-Resistant Patients - Doctor's Guide, 4/7/06
• Cephalon Oncology Compound Lestaurtinib (CEP-701) Granted Orphan Drug Designation for Acute Myeloid Leukemia - Doctor's Guide, 4/4/06
• New Preclinical Research Supports Ceflatonin in Treatment of Acute Myeloid Leukemia - Doctor's Guide, 3/23/06
• SuperGen Announces Results From Combination Study in CLL Published in the Journal of Clinical Oncology - Doctor's Guide, 3/14/06
• Insecticides: Potential Leukemia Risk - WebMD, 1/18/06
• Household Insecticides Associated With Increased Risk of Childhood Leukaemia - Doctor's Guide, 1/17/06 - "The risk of developing acute leukaemia was almost twice as likely in children whose mothers said that they had used insecticides in the home while pregnant and long after the birth"
• St. Jude Projects 90 Percent Cure Rate For Childhood Cancer Acute Lymphoblastic Leukemia - Science Daily, 1/12/06
• Imatinib Alone Not a Long-Term Cure for Chronic Myeloid Leukemia - Doctor's Guide, 12/15/05
• Imatinib Therapy Shows Positive Results After 4 Years in Chronic Myeloid Leukemia - Doctor's Guide, 12/14/05
• FDA Approves IND for SPC2996 in Chronic Lymphocytic Leukaemia - Doctor's Guide, 11/8/05
• Safer bone marrow transplants possible - MSNBC, 9/28/05
• EMEA Grants Orphan Drug Designation to Troxatyl (Troxacitabine) for Treatment of Acute Myeloid Leukemia - Doctor's Guide, 9/27/05
• Blood Stem Cell Transplant from a Relative Better Option for Children with Leukaemia - Doctor's Guide, 8/4/05
• Increased Body Size Linked to Leukemia - WebMD, 8/2/05
• Combined Fludarabine, Cyclophosphamide and Rituximab a Possible New Gold Standard in Chronic Lymphocytic Leukaemia: Presented at ICML - Doctor's Guide, 6/14/05
• Child Leukemia Again Linked to Power Lines - WebMD, 6/2/05
• FDA Grants Orphan Drug Designation for Troxatyl (Troxacitabine) - Doctor's Guide, 5/12/05
• Chronic Lymphocytic Leukemia Patients Reach 5-Year Survival Milestone After Receiving Alemtuzumab Therapy - Doctor's Guide, 5/3/05
• Researchers Show New Drug May Help Treat Certain Forms of Leukemia - Doctor's Guide, 5/2/05
• UT Southwestern Researchers Show New Drug May Help Treat Certain Forms Of Leukemia - Science Daily, 5/2/05
• New Drug Shows Promise in Fighting Gleevec-Resistant Chronic Myeloid Leukemia - Doctor's Guide, 4/21/05
• New Drug May Be Formidable Adversary For Hard To Treat Leukemia - Science Daily, 2/28/05
• Study Finds New Designer Drug Is Potent Treatment For Chronic Myelogenous Leukemia - Science Daily, 2/22/05
• Researchers Blend Folk Treatment, High Tech For Promising Anti-cancer Compound - Science Daily, 2/20/05
• Scientists Disprove Two Tenets Of Common Leukemia - Doctor's Guide, 2/18/05
• Leukemia Vaccine Looks Promising - WebMD, 2/17/05
• Cord Blood Transplantation Now a Viable Option for Adult Leukemia Patients - Doctor's Guide, 1/20/05
• New Childhood Leukemia Drug Approved - WebMD, 12/30/04
• Genzyme Wins FDA OK for Leukemia Drug - Intelihealth, 12/30/04
• New Horizons in Acute Leukemias: An Interview With Jorge E. Cortes, MD - Medscape, 12/20/04
• Study Shows Haploidentical Natural Killer Cells May Provide Hope For Some Patients With AML - Science Daily, 12/17/04
• Peptide Vaccine Can Produce Complete Remission In Myeloid Leukemia Patients - Science Daily, 12/17/04
• Next-Generation Nucleoside Analogue Active in Refractory Childhood Leukemias - Doctor's Guide, 12/8/04
• Effective Treatments Minimize Morbidity in Childhood Leukemia - Doctor's Guide, 12/8/04
• Adolescents With Leukemia Benefit from Early Intensive Chemotherapy - Doctor's Guide, 12/8/04
• Peptide Vaccine Combats Leukemia - Doctor's Guide, 12/8/04
• Chronic Lymphocytic Leukemia Patients Not at Increased Risk of Secondary Cancers - Doctor's Guide, 12/8/04
• New Vaccine Helps Leukemia Patients - WebMD, 12/7/04
• Novel Leukemia Pills Show Promise - WebMD, 12/6/04
• Methylphenidate Improves Attention, Behavior of Children Surviving Acute Lymphoblastic Leukemia, Brain Tumors - Doctor's Guide, 12/2/04
• Stronger Therapy Better For Acute Myeloid Leukemia (AML) With Normal Genetics - Science Daily, 12/1/04
• Leukemia Patients Survive With Stem Cell Transplant - Science Daily, 11/30/04
• Stem Cell Transplant Viable for Many Patients With Leukemia - Doctor's Guide, 11/25/04
• Cord Blood Transplant OK for Adult Leukemia - WebMD, 11/24/04
• Obesity Linked to Acute Leukemia - WebMD, 11/8/04
• Blood Transplants May Be Riskier Than Bone Marrow Transplants In Pediatric Leukemia Patients - Doctor's Guide, 11/2/04
• Improved Acute Lymphoblastic Leukemia Treatment Offers Hope For Eliminating Irradiation - Doctor's Guide, 11/2/04
• FDA Grants Orphan Drug Designation to 17-AAG for Treatment of Chronic Myelogenous Leukemia - Doctor's Guide, 10/26/04
• FDA Grants Orphan Drug Designation for Cloretazine (VNP40101M), Treatment for Acute Myelogenous Leukemia - Doctor's Guide, 10/26/04
• Alemtuzumab Improves Minimal Residual Disease Remissions Survival for Chronic Lymphocytic Leukemia Patients - Doctor's Guide, 10/19/04
• New Therapy For Specific Form Of Leukemia - Science Daily, 10/4/04
• Arsenic Fights Rare Form of Leukemia - WebMD, 9/29/04
• Prolonged Rituximab Shows Promise for Follicular Lymphoma and Mantle Cell Leukemia - Doctor's Guide, 9/16/04
• Rituximab Effective With Minimal Toxicity in Patients With Relapsed or Refractory Hairy Cell Leukemia - Doctor's Guide, 9/14/04
• Rituximab Adds to Efficacy of Fludarabine/Cyclophosphamide in Chronic Lymphocytic Leukaemia - Doctor's Guide, 9/14/04
• Light at Night May Be Linked to Cancer - WebMD, 9/8/04
• Benzene Linked to Childhood Leukemia - WebMD, 8/18/04
• Genes May Explain Leukemia Treatment Failures - WebMD, 8/4/04
• New Drug Helps Kids Fighting Leukemia - WebMD, 7/7/05
• Allogenic Stem-Cell Transplant Can Provide Sustained Disease Control in Patients With Unmutated Chronic Lymphocytic Leukaemia - Doctor's Guide, 7/1/04
• Evidence Suggests that Imatinib Will Lead to Better Survival Rates than Interferon Alpha - Doctor's Guide, 6/16/04
• Imatinib as induction therapy in elderly patients with newly diagnosed Philadelphia-positive acute lymphoid leukaemia - Doctor's Guide, 6/16/04
• Induction With Cladribine (2-CdA), Cytarabine, Mitoxantrone and Granulocyte Colony-stimulating Factor Improves Survival in Resistant and Relapsed Acute Myeloid Leukaemia - Doctor's Guide, 6/14/04
• First-Line Alemtuzumab Has Long-Term Remission and Few Infectious Complications in Patients With B-Cell Chronic Lymphocytic Leukaemia - Doctor's Guide, 6/14/04
• Pentostatin Rituximab Combination Benefits Patients With Resistant/Relapsing Chronic Lymphocytic Leukaemia - Doctor's Guide, 6/9/04
• Erythropoietin Effective in Treating Anaemia in Patients With Chronic Myeloid Leukaemia - Doctor's Guide, 6/9/04
• Alemtuzumab (MabCampath) Eradicates Minimal Residual Disease, Improves Survival in Chronic Lymphocytic Leukemia - Doctor's Guide, 6/9/04
• Adding Rituximab to Fludarabine Therapy for Previously Untreated Patients with Chronic Lymphocytic Leukaemia May Increase Overall, Progression-Free Survival - Doctor's Guide, 5/27/04
• Allogeneic Bone Marrow Transplantation Without Total Body Irradiation Appears Effective In Treating Juvenile Myelomonocytic Leukaemia - Doctor's Guide, 5/19/04
• Bone Marrow Transplant Recovery Takes Years - WebMD, 5/18/04
• Outcome of Childhood Acute Promyelocytic Leukaemia Outcome May Be Improved With All-Trans-Retinoic Acid and Chemotherapy - Doctor's Guide, 4/30/04
• Single-Dose 2-Chlorodeoxyadenosine Achieved Long-Term Response Rates in Hairy Cell Leukaemia - Doctor's Guide, 4/12/04
• Risk-Adapted Treatment Effective in Some Patients With Acute Myeloid Leukemia - Doctor's Guide, 4/12/04
• Voriconazole Appears to Prevent Fungal Relapse in Patients With Leukaemia - Doctor's Guide, 4/8/04
• Increased Complete Remission of Adult Acute Myeloid Leukemia with Daunorubicine and Cytarabine plus Cladribine Induction Treatment - Doctor's Guide, 4/5/04
• Higher Doses Of Imatinib Proven Effective And Safe in Treatment of Chronic Myelogenous Leukemia - Doctor's Guide, 4/1/04
• Weekly 2-chlorodeoxyadenosine Regimen Compared to Daily in Treatment of Hairy Cell Leukaemia - Doctor's Guide, 3/31/04
• Low Dose Interferon-alpha as Effective as Higher Doses for Treating Chronic Myeloid Leukaemia - Doctor's Guide, 3/25/04
• Vascular Endothelial Growth Factor Appears to Decrease In Chronic Myeloid Leukemia Patients Treated With Imatinib - Doctor's Guide, 3/24/04
• Imatinib and Bone Marrow Transplant Are Top Choices for Chronic Myelogenous Leukemia Treatment - Doctor's Guide, 3/12/04
• FDA Awards Fast Track Designation for Cloretazine (VNP40101M) Treatment for Relapsed or Refractory Acute Myeloid Leukemia - Doctor's Guide, 3/8/04
• Toxicity Profile of High-Dose Etoposide Appears Schedule-Dependent - Doctor's Guide, 3/1/04
• Survival Outcome in Chronic-Phase Chronic Myelogenous Leukaemia Appears Better With Imatinib Mesylate Therapy Than For Past Non-Imatinib Treatments - Doctor's Guide, 2/23/04
• Fludarabine-Based Chemotherapy Appears to be Effective but Toxic in Elderly Patients With Refractory Chronic Lymphocytic Leukemia - Doctor's Guide, 2/12/04
• Imatinib Mesylate Reverses Bone Marrow Angiogenesis in Chronic Myeloid Leukaemia - Doctor's Guide, 1/29/04
• Idarubicin Linked To Excessive Toxicity And Withdrawals In Young Acute Myeloid Leukaemia Patients - Doctor's Guide, 1/21/04
• Higher Doses of Imatinib Mesylate Safely Improve Cytogenetic and Molecular Response in Chronic Myeloid Leukemia - Doctor's Guide, 1/15/04
• Filgrastim-Induced Stem Cell Mobilisation During Imatinib Therapy Appears Safe, Feasible In Chronic Myeloid Leukaemia Patients - Doctor's Guide, 1/13/04
• Prognostic Marker of Chronic Lymphocytic Leukaemia Survival Identifiable with Flow Cytometry Assay - Doctor's Guide, 1/9/04
• Intrathecal Methotrexate and High-Dose Intravenous Methotrexate Might Be Substitute for Cranial Irradiation in Children With Acute Lymphoblastic Leukaemia - Doctor's Guide, 1/6/04
• Arsenic Plus All-trans Retinoic Acid More Effective Than Either Alone in Acute Promyelocytic Leukemia - Doctor's Guide, 12/18/03
• Recovery from Relapsed Acute Myeloid Leukaemia is Possible with Reinduction Therapy - Doctor's Guide, 12/16/03
• Chemotherapy for ALL Results in Only Subtle Cognitive Change - Doctor's Guide, 12/11/03
• Elderly with Acute Myelogenous Leukaemia Do Just as Well Without Post-Remission Chemo - Doctor's Guide, 12/11/03
• Rituximab Adds to Fludarabine Efficacy in Chronic Lymphocytic Leukaemia - Doctor's Guide, 12/11/03
• Elderly With Acute Promyelocytic Leukemia Can Benefit From ATRA and Chemo - Doctor's Guide, 12/9/03
• Cyclophosphamide Plus Fludarabine Yields Better Outcome in Chronic Lymphocytic Leukemia Than Fludarabine Alone - Doctor's Guide, 12/8/03
• Epirubicin Adds Benefits to Fludarabine Therapy for Chronic Lymphocytic Leukemia - Doctor's Guide, 12/8/03
• Translocation (8;21) Acute Myeloid Leukaemia Patients Do Not Show Superior Treatment Outcome - Doctor's Guide, 12/3/03
• Thalidomide/Dexamethasone Combination May Effectively Treat Cases of B-chronic Lymphocytic Leukaemia With Myeloma - Doctor's Guide, 11/11/03
• Intermediate Dose Melphalan for Myeloma Effective, Less Toxic Than High Dose - Doctor's Guide, 11/10/03
• Imatinib is Effective Therapy for Chronic Myeloid Leukaemia in Patients Resistant or Intolerant to Interferon Therapy - Doctor's Guide, 11/7/03
• Intensive Induction Therapy May Not Improve Long Term Outcome In Acute Lymphoblastic Leukaemia - Doctor's Guide, 10/30/03
• Clofarabine May Be Superior To Cladribine In Treatment of Paediatric Leukaemia - Doctor's Guide, 10/22/03
• Imatinib Mesylate/Interferon-a Combination Therapy Effective, Safe for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukaemia Patients - Doctor's Guide, 10/20/03
• Nearly Half of Patients with Relapsed or Refractory Acute Leukaemia Respond to New Multidrug Reinduction Protocol - Doctor's Guide, 10/17/03
• Aggressive Therapy for Childhood T-cell Acute Lymphoblastic Leukaemia Significantly Boosts Survival - Doctor's Guide, 10/13/03
• Three Anthracycline Regimens Comparable in Older Patients with Acute Myeloid Leukaemia - Doctor's Guide, 10/9/03
• Interferon Alpha Recommended as First Line Treatment in Elderly Chronic Myeloid Leukemia Patients - Doctor's Guide, 10/7/03
• In Childhood Leukaemia Study, Aggressive Chemotherapy Cuts Deaths By 37% - Doctor's Guide, 10/2/03
• Potential Role of All-Trans-Retinoic Acid And Anthracycline-Based Chemotherapy After Induction in Acute Promyelocytic Leukaemia - Doctor's Guide, 9/29/03
• Unrelated Cord Blood Transplantation Promising Treatment for High-Risk Children with Acute Myeloid Leukaemia - Doctor's Guide, 9/18/03
• All-Trans-Retinoic Acid Thromboembolic Complications Rare and Treatable in Patients With Acute Promyelocytic Leukemic - Doctor's Guide, 9/18/03
• Antithrombin Potential Prophylaxis for Preventing Thrombotic Events in Paediatric Acute Lymphoblastic Leukaemia Patients - Doctor's Guide, 9/17/03
• Lack of Cytogenic Response to Imatinib Linked to Poor Survival in Chronic Myeloid Leukaemia - Doctor's Guide, 9/11/03
• Mylotarg Combined with Intensive Chemotherapy at Induction May Improve Remission Rates in Cases of Acute Myeloid Leukaemia - Doctor's Guide, 9/11/03
• Relapse in Acute Lymphoblastic Leukaemia Patients Linked to Minimal Residual Disease After Allogeneic Stem Cell Transplantation - Doctor's Guide, 9/10/03
• Combination of Adoptive Immunity Transfer by Bone Marrow Transplantation and Lamivudine Clears Hepatitis B Virus in Chronic Carrier - Doctor's Guide, 9/8/03
• Post-Remission Autologous Bone Marrow Transplantation Improves Long Term Survival in Acute Myelogenous Leukaemia Patients - Doctor's Guide, 9/4/03
• Imatinib Mesylate (STI571) Successfully Treats Extramedullary Blast Crisis Of Chronic Myelogenous Leukaemia - Doctor's Guide, 8/29/03
• Splenectomy In Chronic Myelomonocytic Leukaemia Patients Is High Risk Treatment Option For Splenomegaly - Doctor's Guide, 8/25/03
• Disease Activity and Pre-treatment Are Strongest Predictors of Infection in Chronic Lymphocytic Leukaemia Patients - Doctor's Guide, 8/22/03
• HD93 Treatment Trial Shows Consolidation Therapy by Cytogenetic Risk Stratification is Feasible, Effective In Acute Myeloid Leukaemia - Doctor's Guide, 8/22/03
• Taxane Regimen as Effective and Safe in Elderly Patients with Advanced Non-Small Cell Lung Cancer Respond as in Younger Patients - Doctor's Guide, 8/21/03
• Neoadjuvant Chemotherapy Increases Resection Rate and Improves Long-Term Survival in Stage III Non-Small Cell Lung Cancer - Doctor's Guide, 8/21/03
• Granulocyte Colony-Stimulating Factor Priming Plus Chemotherapy Improves Survival Among Standard-Risk Acute Myeloid Leukaemia Patients - Doctor's Guide, 8/21/03
• G-CSF Increases Disease-Free Survival in Standard-Risk AML - Medscape, 8/20/03
• Leukaemia-Associated Antigens Hold Therapeutic Promise for Myeloid Leukaemia Patients - Doctor's Guide, 8/20/03
• Myeloperoxidse-Positive Blast Cells Have Significant Prognostic Value In Acute Myeloid Leukaemia - Doctor's Guide, 8/18/03
• Long-Term Outcomes for Survivors of Childhood Acute Lymphoblastic Leukaemia Affected by Initial Radiation Therapy - Doctor's Guide, 8/13/03
• New Meaning of 'Cured' for Childhood Leukemia - WebMD, 8/13/03
• A Disease Overview of Acute Promyelocytic Leukaemia - Doctor's Guide, 8/12/03
• Full Blood Counts Ineffective in Detecting Relapse in Paediatric Acute Lymphoblastic Leukaemia Patients - Doctor's Guide, 8/8/03
• Allogeneic Haematopoietic Stem Cell Transplantation with Reduced Intensity Conditioning Regimen Effective in Chronic Lymphocytic Leukaemia - Doctor's Guide, 8/4/03
• Ig Levels Reduced In Patients With Chronic Myeloid Leukaemia Treated With Imatinib Mesylate and Resistant to Interferon - Doctor's Guide, 8/1/03
• Nipent (Pentostatin) Active In Treating Chronic Graft-Versus-Host Disease In Children - Doctor's Guide, 7/28/03
• Paternal Smoking Before Conception Increases Risk of Childhood Leukemia in Offspring - Doctor's Guide, 7/17/03
• Fusion Gene Expression Ratios Predict Prognosis In Acute Myeloid Leukaemia -Doctor's Guide, 7/15/03
• Reducing Oral 6-Mercaptopurine Dose During High-Dose Methotrexate Treatment Reduces Myelotoxicity - Doctor's Guide, 7/15/03
• Vaccination with Tumor Cells Triggers Immune Response in Leukemia Patients - Doctor's Guide, 7/14/03
• No Significant Improvement In Relapsed Acute Promyelocytic Leukaemia From Salvage Therapy With All-Trans-Retinoic Acid And Arsenic Trioxide - Doctor's Guide, 7/8/03
• Limited Efficacy Found For Increased Dose Of Imatinib In Relapsed Or Refractory Chronic Or Accelerated Phase Chronic Myelogenous Leukaemia - Doctor's Guide, 7/7/03
• Researchers Review Progress and Challenges in the Therapy of Adult Acute Lymphoblastic Leukemia - Doctor's Guide, 6/26/03
• Pretreatment CD34+ Cell Count May Predict Quality of Peripheral Blood Stem Cell Mobilisation - Doctor's Guide, 6/23/03
• Karyotypic Response Associated with BCR-ABL Reduction in Imatinib Treatment of Chronic Myelogenous Leukaemia - Doctor's Guide, 6/23/03
• Alemtuzumab in Chronic Lymphocytic Leukaemia, Effective But Toxic Needs To Be Minimised - Doctor's Guide, 6/23/03
• Increased P-Glycoprotein In Chronic Myeloid Leukaemia Predicts Poor Response to Imatinib - Doctor's Guide, 6/19/03
• Imatinib Offers Significantly Better Quality Of Life Than Interferon Alfa/Low-Dose Cytarabine For Chronic Phase Chronic Myeloid Leukaemia - Doctor's Guide, 6/13/03
• Imatinib Shows No Benefit For Refractory Or Recurrent Acute Myeloid Leukaemia, High-Risk Myelodysplastic Syndrome, And Myeloproliferative Disorders - Doctor's Guide, 6/13/03
• Dexamethasone More Toxic Than Prednisone As Induction Chemotherapy For Childhood Acute Lymphoblastic Leukaemia - Doctor's Guide, 6/12/03
• Granulocyte Colony-Stimulating Factor Added To Timed-Sequential Chemotherapy Is Safe, Effective For Newly Diagnosed De Novo Acute Myelogenous Leukaemia - Doctor's Guide, 6/5/03
• Less Intensive Chemotherapy Still Effective For Elderly With Promyelocytic Leukaemia - Doctor's Guide, 6/4/03
• Clofarabine Treatment Promising in Some Children With Relapsed Acute Leukemias - Doctor's Guide, 6/2/03
• Filgrastim In Chronic Myeloid Leukaemia Patients Who Achieve Complete Cytogenetic Response Feasible, Safe - Doctor's Guide, 5/28/03
• Imatinib May Help Improve Prognosis Of Chronic Myeloid Leukaemia With Derivative Chromosome 9 Deletions - Doctor's Guide, 5/28/03
• Unrelated Donor Allogeneic Stem Cell Transplantation Better Than Chemotherapy For High-Risk Relapsed Acute Lymphoblastic Leukaemia - Doctor's Guide, 5/27/03
• Long-Term Intrathecal Therapy And Radiotherapy Confer Comparable Survival Rates For Acute Lymphoblastic Leukaemia - Doctor's Guide, 5/22/03
• Idarubicin/Cytarabine Superior To Troxacitabine-Based Regimens In Older Patients With Adverse Karyotype Acute Myeloid Leukaemia - Doctor's Guide, 5/21/03
• Long-Term Results Continue To Show Benefit Of Delayed Intensification Therapy For Lower-Risk Lymphoblastic Leukaemia - Doctor's Guide, 5/21/03
• Granulocyte Colony-Stimulating Factor Primed Bone Marrow Promising For Patients With Haematological Malignancies - Doctor's Guide, 5/21/03
• First-Line, Maintenance Rituximab Therapy Effective And Safe In Chronic Lymphocytic Leukaemia Or Small Lymphocytic Lymphoma Patients - Doctor's Guide, 5/21/03
• Combination Caspofungin And Liposomal Amphotericin Appear Effective Against Invasive Fungal Infections In Leukaemia - Doctor's Guide, 4/1/03
• High Dose Imatinib Mesylate Induces Remission In Chronic Myeloid Leukemia Subset - Doctor's Guide, 3/25/03
• Serum Assay More Precise For Multiple Myeloma Monitoring - Doctor's Guide, 2/6/03
• Europe Approves Fludara (Fludarabine Phosphate) As First-Line Treatment For B-Cell Chronic Lymphocytic Leukemia - Doctor's Guide, 2/6/03
• Dexamethasone Reduces Thromboembolism In Children Treated For Acute Lymphoblastic Leukemia - Doctor's Guide, 1/20/03
• Bryostatin Less Than Impressive In Chronic Lymphocytic Leukemia And Indolent Non-Hodgkin's Lymphoma - Doctor's Guide, 12/16/02
• Fludarabine/Epirubicin Combo For Chronic Lymphocytic Leukemia Improves Remission Rate - Doctor's Guide, 12/16/02
• T-Cell Depletion/Cyclosporine Equal to Methotrexate/Cyclosporine - Medscape, 12/12/02
• Peptide Vaccination with PR1 Peptide Induces Cytogenetic Remission in Acute Myelogenous Leukemia - Doctor's Guide, 12/10/02
• Early Cytogenetic Response Seen with PegIntron (Pegylated Interferon Alpha 2b) plus Glivec (Imatinib) for Early Chronic Myeloid Leukemia - Doctor's Guide, 12/10/02
• High Response Rates Seen with Fludarabine in Chronic Lymphocytic Leukemia - Doctor's Guide, 12/10/02
• Peptide Vaccine Brings Remission of Leukemia - Medscape, 12/9/02
• Acute Myeloid Leukemia Patients in First Relapse Enter Remission with Anti-CD33 Monoclonal Antibody Therapy - Doctor's Guide, 12/9/02
• Trial Continues to Support Imatinib as Front-line Therapy for Chronic Myeloid Leukemia - Doctor's Guide, 12/9/02
• Oral Fludarabine Phosphate Equals Intravenous For First-line Treatment of Chronic Lymphocytic Leukemia - Doctor's Guide, 12/9/02
• Decitabine Has Promising Clinical Activity in Chronic Myeloid Leukemia - Doctor's Guide, 11/14/02
• Alemtuzumab Highly Effective For B-Cell Chronic Lymphocytic Leukemia - Doctor's Guide, 7/24/02
• Imatinib Mesylate Highly Effective In Chronic Phase Myeloid Leukemia - Doctor's Guide, 7/24/02
• Women Cured Of Childhood Leukaemia Should Be Advised To Have Children While They Are Young - Doctor's Guide, 7/3/02
• Custom-Made Vaccine Stimulates Immune Response in Early Follicular Non-Hodgkin's Lymphoma - Doctor's Guide, 6/20/02
• Zevalin (Ibritomomab Tiuxetan) Radioimmunotherapy Shows Promise against B-Cell Non-Hodgkin's Lymphoma - Doctor's Guide, 6/20/02
• Bcl-6 and CD10 Expression Predictive of Disease Progress in Diffuse Large B-Cell Lymphoma - Doctor's Guide, 6/20/02
• Male Sex, Low Physical Activity Linked With Lowered Bone Mineral Density In Leukaemia Survivors - Doctor's Guide, 6/20/02
• Fludarabine and Epirubicin Effective Against Chronic Lymphocytic Leukemia in Elderly Patients - Doctor's Guide, 6/13/02
• French Compassionate-Use Experience With Trisenox (Arsenic Trioxide) Injection Confirms Previously Reported Efficacy, Safety Seen In United States - Doctor's Guide, 6/7/02
• St. Jude Research Proves Physicians Should Rely on Chemotherapy - Doctor's Guide, 6/3/02
• Two Months Quantitative RT-PCR Predicts Cytogenetic Response for Imatinib-Treated Interferon Resistance Chronic Phase CML - Doctor's Guide, 5/20/02
• Nadroparin Effects In Leukaemia Patients Differ By Chemotherapy Stage - Doctor's Guide, 5/16/02
• Campath(R) Study Shows Increased Life Expectancy for Patients with Advanced B-Cell Chronic Lymphocytic Leukemia (B-CLL) - Doctor's Guide, 5/14/02
• Kids in Preschool Get Less Leukemia - WebMD, 5/10/02
• Nursery Attendance May Reduce The Risk Of Childhood Leukaemia - Doctor's Guide, 5/7/02
• Trials Of New Agents For Fludarabine-Refractory Blood Cancers Might Be Warranted Despite Infection Risk - Doctor's Guide, 4/10/02
• Genetic Testing Can Improve Acute Lymphoblastic Leukaemia Treatment - Doctor's Guide, 3/21/02
• Unrelated Bone Marrow Donors Should Be Considered for Children With Acute Leukemia - Doctor's Guide, 3/21/02
• Trisenox (Arsenic Trioxide)/PCR Testing Implicated in Treatment Algorithm for Refractory Acute Promyelocytic Leukaemia - Doctor's Guide, 3/5/02
• Promising Results For Imatinib In Chronic Myelogenous Leukaemia - Doctor's Guide, 2/28/02
• Leukemia drug gets rave review - USA Today, 2/27/02
• Early Positive Gleevec (Imatinib Mesylate) Data in Newly Diagnosed Chronic Myeloid Leukemia Study Prompt Protocol Changes - Doctor's Guide, 1/7/02
• Molecularly Targeted Gleevec Is First Real Glimpse of a Cure - WebMD, 12/26/01
• Imatinib Mesylate Plus Interferon Proves Safe, Feasible in Chronic Phase Chronic Myeloid Leukaemia - Doctor's Guide, 12/12/01
• Bone Marrow Transplantation May Offer Better Survival than Chemotherapy for Chronic Lymphocytic Leukaemia - Doctor's Guide, 12/12/01
• Sustained Haematological Control Still Reported with Gleevec (Imatinib Mesilate) for Chronic Myeloid Leukaemia - Doctor's Guide, 12/11/01
• Glivec (Imatinib Mesylate) Appears To Be Safe and Effective in bcr/abl Positive Chronic Myelogenous Leukaemia - Doctor's Guide, 12/10/01
• Almost Half of Febrile Neutropenia Hospitalisations Occur During First Cycle of CHOP - Doctor's Guide, 12/10/01
• Glivec (Imatinib Mesylate) May Be New standard of Care for Philadelphia Chromosome-Positive Chronic Myeloid Leukaemia - Doctor's Guide, 12/10/01
• Rituximab Improves Response Rates in Relapsed or Refractory B-Cell Lymphoma - Doctor's Guide, 12/10/01
• Intensified Biweekly CHOP Chemotherapy Proves Highly Effective In Aggressive Non-Hodgkin's Lymphoma - Doctor's Guide, 12/10/01
• Mega-CHOP Safe and Effective for Aggressive Non-Hodgkin's Lymphoma - Doctor's Guide, 12/10/01
• Clinicians Consider Glivec (Imatinib Mesylate) Management, Dosing and Response - Doctor's Guide, 12/10/01
• No Increased Morbidity or Mortality for Dexamethasone in Induction Therapy of Childhood Lymphoblastic Leukaemia - Doctor's Guide, 12/9/01
• Hematologic, Cytogenic and Molecular Responses Seen to Gleevec (Imatinib Mesilate) in Patients with Ph+ Chronic Myeloid Leukemia - Doctor's Guide, 12/9/01
• Gleevec (Imatinib Mesylate) Achieves Hematologic Response in Patients with Accelerated or Blastic Phase Chronic myeloid Leukemia - Doctor's Guide, 12/9/01
• Major, Durable Responses to STI571 Seen in Chronic Phase Chronic Myeloid Leukemia - Doctor's Guide, 12/9/01
• Gleevec Data On Patients with CML Promising - Doctor's Guide, 12/9/01
• Nipent (Pentostatin)/Cyclophosphamide Combo Shows Potent Activity in Chronic Lymphocytic Leukemia - Doctor's Guide, 11/13/01
• Trisenox (Arsenic Trioxide) Induces Substantial, Sustained Remission Rates in Relapsed/Refractory Leukemia - Doctor's Guide, 11/7/01
• Trisenox (Arsenic Trioxide) Shows Strong Remission Rates In Relapsed/Refractory Leukemia - Doctor's Guide, 10/5/01
• Kids With Leukemia Doing Better, New Treatments Improve Odds - WebMD, 10/5/01
• Thalomid (Thalidomide) Shows Promise In Myelodysplastic Syndromes - Doctor's Guide, 8/10/01
• Thalidomide Significantly Affects Early-stage Multiple Myeloma - Doctor's Guide, 8/10/01
• Leukemia Drug Shows Early Promise, Stokes Hope For "Magic Bullet" Against Cancer - Intelihealth, 7/25/01
• Research improves marrow grafts - USA Today, 7/2/01
• Cancer Drug [Gleevic] Is Found To Have Limits - Intelihealth, 6/21/01 - "the drug fails in patients with advanced cases of chronic myeloid leukemia, the same cancer it works so well on in early stages. The researchers found that, in late stages of that cancer, tumors have certain genetic mutations that, in effect, outsmart Gleevec"
• High-Risk Procedure Pays Off for Leukemia Patient - WebMD - 6/13/01
• Rituxan (Rituximab) Plus Fludarabine Effective Front-line Therapy For Chronic Lymphocytic Leukemia - Doctor's Guide, 5/16/01
• Leukemia pill [Gleevec] shows promise against stomach cancer - CNN, 5/14/01 - "A study of 148 GIST patients showed 59 percent went into remission, and the results were even better in those with the most common type of mutation"
• FDA Approves Gleevec (Imatinib Mesylate) For Leukemia Treatment -  Doctor's Guide, 5/10/01
• FDA Approves Campath (Alemtuzumab) Humanized Monoclonal Antibody for B-Cell Chronic Lymphocytic Leukemia - Doctor's Guide, 5/8/01
• FDA Approves 'Breakthrough' Leukemia Drug, Gleevec Targets Cancer Cells, Leaves Normal Cells Alone - WebMD, 5/10/01
• Cancer pill [Gleevec/STI-571] wins marketing approval - CNN, 5/10/01 - "51 of 53 CML patients remained in remission one year after treatment. Researchers say while it's possible Gleevec may cure some patients, the benchmark for "cure" is five consecutive years cancer free ... Gleevec works by seeking out and destroying only cancer cells, while healthy cells remain virtually untouched. So far, patients have reported only minimal side effects including nausea, muscle cramps and fluid retention"
• Trisenox (Arsenic Trioxide) Enhances Effects of Glivec (STI-571) Against Chronic Myeloid Leukemia - Doctor's Guide, 5/3/01 - "Trisenox ™ (arsenic trioxide) may make Glivec® (STI-571) more effective in treating chronic myeloid leukemia (CML)"
• Experimental Drug [Glivec] Cures Stomach Cancer, Report Says - Intelihealth, 4/6/01 - "a 55-year-old Finnish woman whose incurable stomach cancer had spread like a brushfire through her abdomen. Every time a growth was surgically removed, several would erupt in its place. Her frustrated doctors at Helsinki University concluded she was beyond the reach of chemotherapy and radiation ... Within two weeks the tumors began to shrink ... the Finnish woman is in good health, living a normal life despite having a cancer that previously was always lethal"
• Drug [Glivec] shows promise in leukemia and intestinal cancer - CNN, 4/4/01 - "I'm incredibly encouraged by our results. I can't think of another agent in all of oncology where we've seen these kinds of dramatic results ... This is a drug that controls cancer with almost no side effects"
• Targeted Therapy for Leukemia May Prove a Breakthrough, Early Results Remarkably Positive - WebMD, 4/4/01
• National Cancer Institute Develops New Drug For Hairy Cell Leukemia - Doctor's Guide, 3/30/01 - "The drug, known by its experimental name, BL-22, produced a complete response in 11 subjects and a partial response in two more in a trial of 15 subjects who were resistant to other treatments for the disease"
• Fludarabine Compared With Chlorambucil As Primary Therapy For Chronic Lymphocytic Leukemia - Doctor's Guide, 3/18/01
• Evidence Supports Association Between Leukemia And Exposure To Cosmic Radiation In Aircrew - Doctor's Guide, 12/22/00
• FDA Committee Recommends Campath (Alemtuzumab) For Leukemia - Doctor's Guide, 12/14/00
• Newer drug holds off leukemia longer - CNN, 12/14/00
• New Leukemia Drug Heralded As Proof Cancer Research Going In Right Direction - Intelihealth, 12/5/00
• New Drug Said To Help Some Leukemia - Intelihealth, 12/4/00
• Cancer drug (Glivec) produces dramatic results - CNN, 12/2/00
• Nipent (Pentostatin) Produces Complete Long-Term Responses In Hairy Cell Leukemia - Doctor's Guide, 11/7/00
• Trisenox (Arsenic Trioxide) Available In US For Leukemia - Doctor's Guide, 10/11/00
• FDA Approves Arsenic Therapy - Intelihealth, 9/27/00
• Oral Fludarabine Proves Safe, Active In Chronic Lymphocytic Leukemia - Doctor's Guide, 8/28/00
• British researchers suspect better living standards linked to childhood leukemia - CNN, 8/4/00
• IV Atragen (Tretinoin) Efficient and Safe in Acute Promyelocytic Leukemia - Doctor's Guide, 5/23/00
• Researchers report promising results with leukemia treatment - CNN, 5/22/00
• FDA OKs Leukemia Drug For Elderly - Intelihealth, 5/19/00
• Mylotarg (Gemtuzumab Ozogamicin) Approved By FDA for Leukemia - Doctor's Guide, 5/18/00
• New Drug Shows Promise for Advanced Leukemia - Doctor's Guide, 4/5/00
• Drug shows promise against one form of leukemia - CNN, 12/3/99

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