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Home > Health Conditions > Alcoholism

Alcoholism

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  • N-acetylcysteine improves impulse control and attenuates relapse-like alcohol intake in long-term drinking rats - Behav Brain Res 2022 Sep 1 - "In conclusion, our findings continue to support the use of NAC as an adjuvant treatment for the maintenance of abstinence in AUD. Moreover, we provide evidence for NAC's efficacy in improving impulse control following drinking, which warrants further investigation in substance use settings" - See n-acetyl cysteine at Amazon.com.
  • Alcoholism and nutrition: a review of vitamin supplementation and treatment - Curr Opin Clin Nutr Metab Care. 2020 Jan 20 - "There are very significant findings with individual vitamin supplementation and combinations that show promise of our understanding of the role of vitamins in the disease of alcoholism and its treatment"
  • Low serum magnesium and 1-year mortality in Alcohol Withdrawal Syndrome - Eur J Clin Invest. 2019 Jun 19:e13152 - "Overall, 1-year mortality was significantly higher among those patients who were magnesium deficient (<0.75 mmol/L) when compared to those who were replete (> 0.75 mmol/L)" - See magnesium supplements at Amazon.com.
  • Fish oil may have positive effects on mood, alcohol craving, new study shows - Science Daily, 5/26/11 - "Researchers at the Indiana University School of Medicine have found at a molecular level a potential therapeutic benefit from these dietary supplements for treating alcohol abuse and psychiatric disorders ... In a multi-year study, researchers showed conclusive behavioral and molecular benefits for omega 3 fatty acid given to mice models of bipolar disorder. The fatty acid DHA, which is one of the main active ingredients in fish oil, "normalized their behavior," ... The mice that were given DHA normalized their behavior, they are not depressed and when subjected to stress, they do not become manic ... When we looked into their brains, using comprehensive gene expression studies, we were surprised to see that genes that are known targets of psychiatric medications were modulated and normalized by DHA ... These bipolar mice, like some bipolar patients, love alcohol. The mice on DHA drank much less; it curtailed their alcohol abusive behavior ... There is now substantial evidence at the molecular level that omega-3 fatty acids work on the brain in ways similar to psychiatric drug ... Omega 3 fatty acids are known to be good for one's health, good for one's brain, and lack major side-effects, as opposed to some psychiatric medications" - See Jarrow Max DHA at Amazon.com.
  • Treatment with kudzu extract does not cause an increase in alcohol's intoxicating effects, study finds - Science Daily, 1/18/11
  • Zinc Supplements During Pregnancy May Counteract Damage From Early Alcohol Exposure - Science Daily, 2/2/09 - "Animal research has shown that binge drinking – even just once – during early pregnancy can cause numerous problems for the fetus, including early postnatal death. Fetal zinc deficiency may explain some of the birth defects and neurodevelopmental abnormalities associated with alcohol exposure. New rodent findings are the first to show that dietary zinc supplements throughout pregnancy can reduce some alcohol-related birth defects"
  • Antioxidants May Protect Against Alcohol Damage - Intelihealth, 6/3/03 - "fed rats a liquid diet containing alcohol for six weeks ... They found a 66 percent decrease in the number of new cells in crucial parts of the brain and an increase in cell death of more than 227 percent ... But in rats that also received injections of the antioxidant ebselen, the damage to developing cells did not occur ... The antioxidant ebselen was used because it is known to have protective effects in the liver and digestive tract and has few side effects in humans"
  • Comparison of hypericum extracts with imipramine and fluoxetine in animal models of depression and alcoholism - Eur Neuropsychopharmacol 1999 Dec;9(6):461-8 - "The present study suggests that hypericum extracts have antidepressant-like properties which resemble those of clinically established antidepressants, and that Remotiv may be an interesting adjunct for the treatment of alcoholism"

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