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Fosamax (alendronate)
Fosamax® (alendronate)
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News & Research:
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Long
term use of oral bisphosphonates may double risk of esophageal cancer, study
finds - Science Daily, 9/2/10 - "Typically,
oesophageal cancer develops in one per 1000 people at age 60-79 over five
years. Based on their findings, the authors estimate that with five years'
use of oral bisphosphonates this would increase to two cases per 1000 people
taking bisphosphonates over five years"
-
Can vitamin D compete with bone drugs? (ATOM) 0 betterbones.com, 8/4/10
- "At the end of the day, vitamin D was shown to
reduce more fractures than the popular bisphosphonate drugs"
-
Fosamax: Higher Risk of Jawbone Death? - WebMD, 1/2/09 -
"After having teeth pulled, 4% of patients in a
study who were taking Fosamax developed a dangerous condition called
osteonecrosis of the jaw, USC researchers report. None of the tooth
extraction patients not taking Fosamax developed osteonecrosis ... The
condition, sometimes called jawbone death, occurs when bone in the jaw fails
to heal after a minor trauma. It results in pain, swelling, infection, and
exposed bone"
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FDA OKs First Generic Fosamax - WebMD, 2/6/07 -
"The FDA today approved the first generic version of the osteoporosis drug
Fosamax (alendronate)"
- Teriparatide
Increases BMD More Than Alendronate in Glucocorticoid-Induced Osteoporosis
- Medscape, 11/19/07
- How Long to Take
Alendronate for Osteoporosis? - Medscape, 2/26/07
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Fosamax Break Won't Up Fracture Risk - WebMD, 12/26/06
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Treating Osteoporosis: What Works Best? - WebMD, 8/10/05 -
"Treatment with parathyroid hormone increases bone
density. But women who took parathyroid hormone for a year progressively
lost bone density afterward unless they took Fosamax"
-
New Study Provides in-Depth Look at How Osteoporosis Treatments Function
Within Bone - Doctor's Guide, 8/9/05
-
Alendronate May Not Be Cost-Effective in Postmenopausal Women With
Osteopenia - Medscape, 5/5/05
-
Osteoporosis Drug, Vitamin D Now in 1 Pill - WebMD, 4/11/05 -
"The FDA has approved Fosamax Plus D, a once-weekly
pill that contains both the osteoporosis drug Fosamax and the bone-building
nutrient vitamin D"
-
FDA Approves Fosamax Plus D (Alendronate Sodium/Cholecalciferol With Vitamin
D) to Reduce Risk of Hip and Spine Fractures - Doctor's Guide, 4/8/05
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Rapid Improvement Seen in Osteoporotic Patients Who Adhere to Weekly
Alendronate Schedule - Doctor's Guide, 10/5/04
- Alendronate May Be
Superior to Risedronate for Increasing BMD - Medscape, 10/4/04
-
Fosamax (Alendronate) Appears To Provide Greater Increases In Bone Mineral
Density, Reductions In Markers Of Bone Turnover - Doctor's Guide,
9/29/04
- Alendronate and
Risedronate for the Treatment of Postmenopausal Osteoporosis: Clinical
Profiles of the Once-Weekly and Once-Daily Dosing Formulations -
Medscape, 7/19/04
-
Alendronate Cost-Effective In Elderly Men With Low Bone Mass and Previous
Vertebral Fractures - Doctor's Guide, 7/8/04
-
Weekly Fosamax (Alendronate) Shows Benefits Over Daily Evista (Raloxifene)
for Bone density and Bone Turnover Markers at 6 Months - Doctor's Guide,
5/21/04
-
Alendronate May Offer Better Improvements in Bone Mineral Density and Bone
Turnover Than Raloxifene - Doctor's Guide, 4/13/04
-
Long-Term Alendronate Appears Beneficial for Postmenopausal Women with
Osteoporosis - Doctor's Guide, 3/18/04
- Fosamax Remains
Safe and Effective Long-Term - WebMD, 3/17/04
-
Combining Hormone Therapy and Alendronate Has No Bone Mass Benefit over
Monotherapy in Elderly Women with Osteoporosis - Doctor's Guide, 2/23/04
-
Alendronate Improves Bone Mineral Density After Total Knee Arthroplasty
- Doctor's Guide, 12/11/03
-
Alendronate Offers Promising Treatment for Transient Osteoporosis -
Doctor's Guide, 11/20/03
-
Adding Cyclic Parathyroid Hormone to Alendronate an Efficient and Economical
Osteoporosis Treatment - Doctor's Guide, 10/12/03
-
Alendronate Suppresses the Beneficial Effects of Parathyroid Hormone Therapy
in Men with Osteoporosis - Doctor's Guide, 10/9/03
-
Alendronate Superior to Raloxifene in Increasing Bone Mineral Density -
Doctor's Guide, 10/7/03
-
Significant Increases in Bone Mineral Density With Alendronate Over
Raloxifene in Head-To-Head Study - Doctor's Guide, 10/6/03 -
"In the first head-to-study comparing a weekly
dosage of alendronate with a daily dosage of
raloxifene for postmenopausal women with osteoporosis, alendronate
produced significantly greater increases in bone mineral density (BMD) in
the spine and hip"
-
Alendronate Beneficial for Women with Both Natural and Surgical Menopause
- Doctor's Guide, 9/29/03
-
Alendronate Helps Maintain Bone Mass In Patients With Asymptomatic Primary
Hyperparathyroidism - Doctor's Guide, 9/25/03
-
Higher Bone Mineral Density Maintained by Continuing Alendronate -
Doctor's Guide, 9/24/03
-
Parathyroid Hormone More Effective Alone than When Combined with Alendronate
for Osteoporosis - Doctor's Guide, 9/24/03
-
Alendronate/Hormone Replacement Therapy Combination Safe, More Effective
Treatment for Osteoporosis in Elderly Women - Doctor's Guide, 5/30/03 -
"after 3 years total hip
BMD increased an average 5.9% in the combinatorial group, 4.2% in the
alendronate only group, 3.0% in the HRT
only group and was maintained in the placebo group"
-
Alendronate + NSAIDs Causes No Additional Upper Gastrointestinal Adverse
Events for Osteoporosis Patients - Doctor's Guide, 5/22/03
-
Hormone Replacement Therapy/Alendronate Combination Safe, Effective for
Prevention and Treatment of Osteoporosis in Older Women - Doctor's
Guide, 5/21/03
-
Combination therapy couples hormone replacement with the drug alendronate
- HealthDay, 5/20/03
- Once-Weekly
Alendronate Superior to Raloxifene for Spine and Hip BMD - Medscape,
4/28/03
-
Eight-Month Neoadjuvant Hormonal Therapy Not Superior to Three Months for
Decreasing PSA Recurrence - Doctor's Guide, 4/28/03
-
Alendronate May Add to Benefits of Testosterone in Men with Osteoporosis
- Doctor's Guide, 4/28/03
-
Alendronate Helps Save Bone After Hormone Replacement Therapy Discontinued
- Doctor's Guide, 4/25/03
-
Greater Increases in Bone Mineral Density with Raloxifene Plus Alendronate
Compared to Either Drug Alone - Doctor's Guide, 4/7/03
-
Osteopororis Drugs Tied to Eye Problems - HealthDay, 3/19/03 - "A class
of osteoporosis drugs has been found
to cause several eye problems, some of them serious ... Bisphosphonates are
sold in the United States under the names Fosamax,
Actonel, Zometa, Didronel, and Skelid"
- What’s Best for Bones?
- Dr. Weil, 3/4/03
-
Once-Weekly Alendronate Effective In Treating Postmenopausal Osteoporosis
- Doctor's Guide, 11/25/02
-
Hormone Therapy Plus Alendronate Better for Bone Density than Hormone
Therapy Alone - Doctor's Guide, 10/8/02
-
Bisphosphonate Differ In Gastric-Ulcer Rates - Doctor's Guide, 10/7/02 -
"The bisphosphonate
risedronate is associated with fewer
gastric ulcers than does alendronate"
-
Alendronate Benefits Can Persist After Withdrawal of Treatment -
Doctor's Guide, 9/23/02
-
Treating & Preventing Osteoporosis - Life Extension Magazine, 9/02 -
"From systematic research the best external evidence
is available for a supplementation with
calcium and vitamin D and a therapy
with the bisphosphonates alendronate or
risedronate, as well as the selective estrogen receptor modulator
raloxifene (Evista)."
-
Alendronate Boosts Bone Mineral Density in Children with Rheumatic Diseases
and Secondary Low Bone Mass - Doctor's Guide, 8/21/02
-
Once Weekly Preferred Over Once Daily Alendronate Regimen - Doctor's
Guide, 6/21/02
-
Once-Weekly Alendronate as Good as Twice-Weekly and Once-Daily Regimens
- Doctor's Guide, 5/14/02
-
Results Of Head-To-Head Efficacy Study Of Osteoporosis Drugs Unveiled -
Fosamax® (Alendronate Sodium), The Only Once Weekly Osteoporosis Medication
Approved In Canada, Shown To Be More Effective Than Risedronate -
Doctor's Guide, 5/13/02 - "In the first head-to-head
efficacy study(1) comparing Fosamax® (alendronate sodium) 70 mg once weekly
and
Actonel® (risedronate) 5 mg once daily,
alendronate was shown to be more effective in the treatment of
postmenopausal osteoporosis"
-
First Report of Severe Hypocalcaemia During Alendronate Treatment -
Doctor's Guide, 5/6/02
- Stopping Spine
Fractures Caused by Anti-Inflammatory Steroids - WebMD, 10/29/01
- Fosamax (Alendronate)
Prevents Bone Mineral Loss After Kidney Transplant - Doctor's Guide,
10/17/01
- Postmenopausal
Osteoporosis Patients Prefer Fosamax Once Weekly Over Fosamax Once Daily
- Doctor's Guide, 10/15/01
- Growth Hormone,
Alendronate And Tissue-Selective Estrogen All Effective In Osteoporosis
- Doctor's Guide, 6/21/01
- Once Weekly Alendronate As
Effectively As Daily Treatment For Osteoporosis - Doctor's Guide,
6/20/01
- Weekly Fosamax
(Alendronate) Shows Equivalent Increases In Bone Density as Daily Regimen
- Doctor's Guide, 6/20/01
- Once-Weekly Fosamax
Effective For Osteoporosis - Doctor's Guide, 6/17/01
-
Once-Weekly Fosamax (Alendronate) In US For Treatment, Prevention Of
Postmenopausal Osteoporosis - Doctor's Guide, 10/24/00
- FDA Approves
First Drug for Male Osteoporosis - WebMD, 10/3/00
- Fosamax Decreases
Disability In Osteoporosis - Doctor's Guide, 2/10/00
- Once Weekly Fosamax
Equally Effective To Once Daily Regimen For Osteoporosis - Doctor's
Guide, 11/23/99
- Fosamax Prevents Loss Of
Bone Mass Following Hip Replacements - Doctor's Guide, 11/15/99
- New Study Shows Fosamax
Use Results in Higher Costs - Doctor's Guide, 10/1/99
- Alendronate Effective In
Men With Osteoporosis - Doctor's Guide, 10/1/99
- Fosamax Prevented Rapid
Bone Loss In Women Who Discontinued HRT - Doctor's Guide, 5/10/99
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