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Anti-aging research > Phenylalanine
Phenylethylamine (PEA)
Specific Recommendations:
News & Research:
-
Happily ever after? It's all in your head - CNN, 2/14/02 - See the
video. Claims that love is dependent on a cocktail of chemicals (dopamine,
norepinephrine and
PEA) and that oxytocin is responsible for
bonding and that
vasopressin is responsible for monogamy.
- Body Makes
Natural Antidepressant After Moderate Exercise - WebMD, 9/27/01 -
"Even moderate exercise apparently raises levels of
a brain chemical that improves a person's mood ... The substance is
phenylethylamine, or PEA, a natural stimulant produced by the body. It is
related to amphetamines but does not have the long-lasting effects that make
"speed" or "ice" such deadly drugs ... moderate exercise increases PEA
levels for most people"
-
Exercise Levels Of Phenylethylamine May Damp Depression - Doctor's
Guide, 9/27/01 -
"Administration of phenylethylamine or its precursor
L-phenylalanine, in conjunction with selegiline, a selective monoamine
oxidase B inhibitor, has been reported to alleviate depression and to
produce improvements in mood. The effects are sustained and also apparent in
some patients who are insensitive to conventional treatment"
- When It Comes to
Love, the Nose Knows - WebMD, 2/14/01-
"I believe that PEA may be the hormone of libido"
- Amino
Acids anyone? - DrBob.org -
"L-phenylalanine
can also be converted (through a separate pathway) to phenylethylamine, a
substance that occurs naturally in the brain and appears to elevate mood."
- Psychotropic
Drug-Induced Sexual Dysfunction - Medscape, 7/99, -
"Amphetamine-like PEA is a stimulant whose levels
spike at orgasm and ovulation and is believed to mediate feelings of romance
and love. Its levels are increased by monoamine oxidase inhibitors"
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Natural Remedies for Depression - Nutrition Science News, 2/99 -
"D-phenylalanine, which does not normally occur in
the body or in food, is metabolized to phenylethylamine (PEA), an
amphetaminelike compound that occurs normally in the human brain and has
been shown to have mood-elevating effects. Decreased urinary levels of PEA
(suggesting a deficiency) have been found in some depressed patients.7
Although PEA can be synthesized from L-phenylalanine, a large proportion of
this amino acid is preferentially converted to L-tyrosine. D-phenylalanine
is therefore the preferred substrate for increasing the synthesis of
PEA--although L-phenylalanine would also have a mild antidepressant effect
because of its conversion to L-tyrosine and its partial conversion to PEA.
Because D-phenylalanine is not widely available, the mixture
D,L-phenylalanine is often used when an antidepressant effect is desired"
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