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Blood Thinners & antiplatelet agents

Popular Supplements:

• aspirin / ginkgo / fish oil / policosanol

Alternative News:

• Relationship Amongst Vitamin K Status, Vitamin K Antagonist Use and Osteoarthritis: A Review - Drugs Aging 2022 May 30 - "vitamin K antagonists (VKAs) ... in limited retrospective and prospective studies, the use of VKAs is associated positively with OA occurrence and knee/hip replacement" - See vitamin k2 at Amazon.com.
• Aspirin and warfarin equally effective for most heart failure patients, study suggests - Science Daily, 5/2/12
• Aspirin Beats Coumadin for Brain Blockage - WebMD, 3/30/05 - "Aspirin is safer and no less effective than Coumadin for treating dangerously blocked brain arteries ... many patients with blocked brain arteries may be able to avoid the expense and complications of treatment with Coumadin (also known by its generic name, warfarin)"
• Herbal Remedy St. John’s Wort Amplifies Effect Of Blood-thinning Drug Plavix, U-M Study Suggests - Science Daily, 3/16/05
• St. John's Wort and Plavix May Be Risky Combo - WebMD, 3/8/05 - "St. John's wort, used by many for depression, increases the effect - and the bleeding risk - of Plavix, a widely used blood thinner"
• Ginseng a No-No for Patients on Coumadin - WebMD, 7/6/04
• Herbal Supplement Ginseng Reduces Effects Of Warfarin - Doctor's Guide, 7/6/04
• Aspirin As Effective As Ticlopidine In African American Antiplatelet Stroke Prevention Study - Doctor's Guide, 6/11/03
• Aspirin May Be Better Than Ticlopidine for Recurrent Stroke Prevention in African Americans - Medscape, 6/10/03 - "Ticlopidine (Ticlid; Roche) does not appear to be superior to aspirin in preventing recurrent strokes in African-American patients"
• Is There a Natural Alternative to Coumadin? - Dr. Weil, 2/1/02
• US Anticoagulation Clinics Underuse Vitamin K - Doctor's Guide, 7/9/01
• Low-Dose Vitamin K Treats Excessive Anticoagulation - Doctor's Guide, 7/9/01

General Information:

• Anticoagulant and Antiplatelet Drugs - Definition, Purpose, Description, Recommended dosage, Precautions, Side effects, Interactions - surgeryencyclopedia.com

CME:

• Medscape CME courses on blood thinners
• Anticoagulation Therapy - U.S. Pharmacist, exp. 4/30/01

News & Research:

• Oral anticoagulants: A plausible new treatment for Alzheimer's disease? - Br J Pharmacol 2023 Jan 12 - "Most studies reported a compelling decreased incidence of composite dementia in anticoagulated atrial fibrillation individuals, with the highest benefit for direct oral anticoagulants"
• Benefits and harms of oral anticoagulants for atrial fibrillation in nursing home residents with advanced dementia - J Am Geriatr Soc 2022 Oct 30 - "In the study sample, 72.0% were female, 82.7% were aged ≥80 years, and 13.5% were nonwhite. Mean CHA2 DS2 VASC score was 6.19 ± 1.58. In multivariable survival analysis, anticoagulation was associated with decreased risk of death (HR 0.71, 95% CI 0.67-0.75) and increased bleeding risk (HR 1.15, 95% CI 1.02-1.29); the association with stroke risk was not significant (HR 1.08, 95% CI 0.80-1.46). Results were similar in models with IPT weighting. While >50% of patients in both groups died within a year, median weighted survival was 76 days longer for anticoagulated individuals ... Persons with advanced dementia and AF derive clinically modest life prolongation from anticoagulation, at the cost of elevated risk of bleeding. The relevance of this benefit is unclear in a group with high dementia-related mortality and for whom the primary goal is often comfort"
• Vitamin K Antagonists and TBI: A Deadly Combination? - Medscape, 7/11/22 - "vitamin K antagonists (VKA) ... Preinjury use of direct oral anticoagulants (DOAC) was also associated with worse outcomes, although not nearly as high as use of VKA. Adenosine diphosphate inhibitors (ADPi) were not linked to higher rates of death or surgery at 30 days ... To explore the issue, researchers analyzed data from 57,056 patients with TBI, most of whom were diagnosed with concussion or mild TBI. Overall, 0.9% were treated with DOAC, 7.1% with VKA (all warfarin), and 2.3% an ADPi ... Mortality at 30 days was 15.4% in the VKA group, 8.4% in the DOAC group, and 7.1% in patients without OAC"
  • Direct oral anticoagulants (DOACs) - Vascular Medicine - "The four DOACs currently available in the United States are dabigatran, rivaroxaban, apixaban, and edoxaban"
• Oral anticoagulants and outcomes in adults ≥80 years with atrial fibrillation: A global federated health network analysis - J Am Geriatr Soc 2022 May 19 - "oral anticoagulation (OAC) ... non-vitamin-K antagonist oral anticoagulant (NOAC) ... Use of a NOAC was associated with improved outcomes compared to warfarin, and compared to no OAC, except for a small but statistically significant higher risk of major bleeding"
• Comparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice: GLORIA-AF Registry - Clin Res Cardiol 2022 Mar 16 - "Patients treated with dabigatran had a 41% lower risk of major bleeding compared with rivaroxaban, but similar risks of stroke, MI, and death. Relative to apixaban, patients treated with dabigatran had similar risks of stroke, major bleeding, MI, and death. Rivaroxaban relative to apixaban had increased risk for major bleeding, but similar risks for stroke, MI, and death"
• Older Anticoagulants Increase Risk of Delayed Brain Hemorrhage After Trauma - Medscape, 12/2/21 - "clinicians should consider repeat head CT when trauma patients are taking older anticoagulant/antiplatelet medications, articularly warfarin (Coumadin, Bristol-Meyers Squibb) and clopidogrel (Plavix, Bristol-Meyers Squibb/Sanofi)"
• Kidney Disease Affects Response To Blood Thinner - Science Daily, 3/1/09
• Optimal Dose Management Of Warfarin Improves Anticoagulation Control, Study Shows - Science Daily, 12/22/08
• Study: Stopping Plavix May Be Risky - WebMD, 2/5/08
• Severe Bleeding Rate With Clopidogrel/Aspirin Comparable to That of Warfarin - Doctor's Guide, 11/6/07
• New Blood Thinner Promising - WebMD, 11/5/07
• Staying on Plavix Cuts Stent Risk - WebMD, 12/5/06
• Dangers of Stopping Clopidogrel (Plavix) for Patients With Stents and Certain Other Conditions - Doctor's Guide, 3/17/06
• Clopidogrel Helps Patients With Established Heart Disease; Not "at-Risk" Individuals - Doctor's Guide, 3/15/06
• Blood-Thinning Drugs Raise Alarm in Stroke Victims - ABC News, 1/6/06
• Did blood thinners worsen Sharon's stroke? - MSNBC, 1/5/06
• Arixtra Showed Comparable Efficacy to Lovenox/Clexane With Significantly Less Major Bleeding in Patients With Acute Coronary Syndromes - Doctor's Guide, 9/9/05
• New Blood Thinner May Reduce Bleeding Risks - WebMD, 9/6/05
• Antiplatelet Therapy: One Size Does Not Fit All Patients With CVD - Physician's Weekly, 7/25/05
• Three Anti-platelet Drugs Used In Combination Are Safe - Science Daily, 3/15/05
• Plavix Saves Lives From Severe Heart Attacks - WebMD, 3/9/05
• Adding Clopidogrel to Aspirin Therapy Reduces Risk of Death and Complications After Major Heart Attacks - Doctor's Guide, 3/9/05
• Prasugrel Shows Better Platelet Inhibition Than Clopidogrel - Doctor's Guide, 3/9/05
• New Blood Thinner Works as Well as Coumadin - WebMD, 2/8/05
• Drug Lowers Risk of Death After Heart Attack - WebMD, 1/25/05
• A Blood-thinner Administered Once Daily Prevents Deep Vein Thrombosis in Hospitalized Patients - Doctor's Guide, 8/17/04
• Stroke Drugs May Increase Bleeding in Gut - WebMD, 7/22/04
• Studies: New Blood Thinners No Better - Intelihealth, 7/6/04
• Some Heart Attack Patients May Be Resistant to Clopidogrel - Doctor's Guide, 6/9/04
• Low Molecular Weight Heparin as Effective as Unfractionated Heparin During Myocardial Infarction - Doctor's Guide, 3/25/04
• ASA-Clopidogrel Combination Enhances Antiplatelet Response in Cerebrovascular Disease - Doctor's Guide, 2/10/04
• Ximelagatran Appears As Effective As Warfarin for Prevention of Stroke and Systemic Embolism in Select Atrial Fibrillation Patients - Doctor's Guide, 11/21/03
• Fixed-Dose Ximelagatran as Safe, More Effective Than Warfarin for Postoperative Thromboprophylaxis - Doctor's Guide, 11/13/03
• New Blood-Thinning Drug Shows Promise - Intelihealth, 11/12/03
• Ximelagatran Superior to Warfarin for Prevention of Venous Thromboembolism Following Total Knee Replacement Surgery - Doctor's Guide, 10/30/03
• New blood thinner offers first potential alternative in 50 years - USA Today, 10/29/03
• Milder Strokes with Common Blood Thinners - Physician's Weekly, 10/6/03
• Aspirin Therapy: How Much Is Too Much? - WebMD, 9/22/03 - "In this new study, higher doses of aspirin were no more effective than low-dose aspirin therapy at preventing heart attacks and strokes ... Just under 2% of the patients given low-dose aspirin alone experienced life-threatening bleeding events, compared with close to 4% of patients taking more than 200 mg of aspirin a day. Among patients taking aspirin and Plavix, 3% of patients in the low-dose aspirin groups experienced serious bleeding vs. 5% of those in the high-dose aspirin group"
• Outpatient Use Of Low Molecular Weight Heparin as Effective but Cheaper than Hospital Use Of Unfractionated Heparin - Doctor's Guide, 9/22/03
• Increased Gastrointestinal Bleeding in High-Risk Patients Taking Clopidogrel - Doctor's Guide, 9/11/03
• Aspirin, Coumadin Make Strokes Milder - WebMD, 9/10/03
• Conventional-Intensity Superior to Low-Intensity Warfarin in Preventing Recurring Venous Thromboembolism - Doctor's Guide, 8/13/03
• Low Molecular Weight Heparin Preferred Anticoagulant Therapy for Outpatients - Doctor's Guide, 8/1/03
• Bleeding Time Unaffected by Addition of Cilostazol to Aspirin or Clopidogrel in Peripheral Arterial Disease Patients - Doctor's Guide, 6/10/03
• Poor Physician Compliance with Heparin Guidelines Results in Haemorrhage - Doctor's Guide, 6/9/03
• Long-term Warfarin Effective in Preventing Catastrophic Antiphospholipid Syndrome Reoccurrence - Doctor's Guide, 6/4/03
• Abciximab May Work On Secondary Clots In Stroke - Doctor's Guide, 5/27/03
• Platelet Count May not be Indicative of Heparin-Induced Thrombocytopaenia - Doctor's Guide, 5/26/03
• Anticoagulation Therapy No Better than Aspirin for Acute Spontaneous Cervical Artery Dissection - Doctor's Guide, 5/22/03
• Low-Intensity Anticoagulation Effective And Safe In Mitral Stenosis And Atrial Fibrillation - Doctor's Guide, 4/16/03
• Low-Intensity Warfarin Curbs Recurrent Venous Thromboembolism - Doctor's Guide, 4/10/03
• A Giant Advance in Anticoagulation Therapy for High-Risk Atrial Fibrillation - Doctor's Guide, 4/3/03
• Atrial Fibrillation Cardioversion With Enoxaparin Achieves Non-Inferior Efficacy With Unfractionated Heparin - Doctor's Guide, 3/31/03
• Triflusal No Better Than Aspirin In Preventing Vascular Events After Stroke - Doctor's Guide, 3/27/03
• Initial Warfarin Dosing Can Be Improved with Use of Simple Clinical Criteria - Doctor's Guide, 3/5/03
• Prothrombin Time Should Be Monitored In Cancer Patients Receiving Both Warfarin, Fluorouracil - Doctor's Guide, 2/25/03
• Coumadin for Blood Clots in Legs - WebMD, 2/24/03
• Low Dose Warfarin Prevents Recurrence Of Blood Clots - Doctor's Guide, 2/24/03
• Warfarin-related Intracerebral Hemorrhage Mortality Appears Dose Dependent - Doctor's Guide, 2/18/03
• Bivalirudin Caused Less Bleeding Than Heparin During PCI - Medscape, 2/18/03
• Stroke Trial Halted when Ticlopidine Fails to Outperform Aspirin in African Americans - Doctor's Guide, 2/18/03
• Warfarin Does Not Prevent Recurrent Strokes in Patients Who Fail Aspirin Therapy - Doctor's Guide, 2/13/03
• Cilostazol Effective For Claudication In Both Diabetics And Non-Diabetics - Doctor's Guide, 2/11/03
• Heparin Infusion Rate Influenced by Body Weight, Other Factors in Acute Coronary Syndrome - Doctor's Guide, 12/16/02
• Long Term Dalteparin Tops Oral Anticoagulant Therapy in Cancer Patients with Venous Thromboembolism - Doctor's Guide, 12/12/02
• Low Molecular Weight Heparin May Be Safe, Effective for Moving Patients to Outpatient Setting Sooner after Surgery - Doctor's Guide, 12/11/02
• More "Super Aspirin" Protects Heart Better - WebMD, 11/19/02 - "About 50,000 heart attacks, strokes, and deaths could be prevented if every angioplasty patient added a "super aspirin" chaser to their daily aspirin every day for a year after the procedure ... The "super aspirin" Plavix is a more powerful anti-clot drug than aspirin ... According to the latest study, taking it daily for a year cuts the risk for death, heart attack, or stroke by 27% compared to patients who just took aspirin and a dummy pill for a year"
• Low-Molecular-Weight Heparin Prevents Bleeding In Renal Insufficiency, Acute Coronary Syndromes - Doctor's Guide, 11/19/02
• Patients on Anticoagulants Not Undergoing Monitoring of Dosage and Platelet Count - Doctor's Guide, 10/3/02
• Low-Molecular-Weight Heparin Leads To Significantly Fewer Thromboses Than Unfractionated Heparin After Angioplasty - Doctor's Guide, 9/27/02
• Warfarin an Independent Risk Factor for Adverse Events in Class II and Class IV Heart Failure Patients - Doctor's Guide, 9/27/02
• Warfarin/Aspirin Mix Better Than Aspirin Alone After Myocardial Infarction - Doctor's Guide, 9/26/02
• Strategies Outlined For Primary, Secondary Prevention of Stroke - Doctor's Guide, 9/18/02 - "The most recent evidence suggests that there are four primary prevention strategies for stroke: adequate blood pressure reduction, treatment of hyperlipidemia, antithrombotic therapy in atrial fibrillation patients and antiplatelet therapy in myocardial infarction patients"
• Reviparin Safe, Effective in Reducing Deep Vein Thrombosis During Prolonged Immobilization - Doctor's Guide, 9/5/02
• Low Molecular Weight Heparin Superior to Unfractionated Heparin in Cardioversion of Atrial Fibrillation - Doctor's Guide, 9/3/02
• Enoxaparin Safer than Warfarin in Cancer Patients with Vein Thrombosis - Doctor's Guide, 8/20/02
• Early-Onset Heparin-Induced Thrombocytopenia Related To Previous Heparin Treatment - Doctor's Guide, 7/18/02
• Postpartum Women Higher Warfarin Doses - Doctor's Guide, 3/25/02
• Clot-buster drugs can put elderly at risk - USA Today, 3/11/02
• Light-weight Heparin has Heavy-weight Results in Heart Attack Treatment - Doctor's Guide, 3/5/02
• FDA Expands Use Of Plavix (Clopidogrel Bisulfate) To Unstable Angina Or Heart Attack - Doctor's Guide, 2/28/02
• Enoxaparin Superior To Heparin In Treating Unstable Coronary Artery Disease - Doctor's Guide, 2/25/02
• Low Molecular Weight Heparin No More Effective than Unfractionated Heparin - Doctor's Guide, 12/11/01
• Aspirin And Warfarin Equal In Recurrent Stroke Prevention - Doctor's Guide, 11/15/01
• Low Molecular Weight Heparin Safe In Combination With Glycoprotein IIb/IIIa Inhibitors - Doctor's Guide, 9/5/01
• Bivalirudin Not Superior to Heparin But Does Prevent Heart Attacks - Doctor's Guide, 9/3/01
• A Real Dynamic Duo -- Super Aspirin and Plain Aspirin -- Offer Protection After Heart Procedures - WebMD, 8/16/01
• Warfarin Treatment In Children Undergoing Cardiac Surgery May Impair Bone Metabolism - Doctor's Guide, 7/11/01
• New Pill [Exanta] Looks Promising For Safer, More Convenient Blood Clot Prevention - Intelihealth, 7/11/01
• Exercise/Heparin May Grow New Blood Vessels, Improve Blocked Arteries In Children - Doctor's Guide, 5/29/01
• Blood thinner (Plavix) could save thousands - USA Today, 3/19/01
• Study Backs Heart Attack Drug - Intelihealth, 3/19/01 - "The heart drug Plavix reduces the risk of new heart attacks, strokes and death by 20 percent a year in people being treated for mild heart attacks and bad chest pain"
• Heparin May Reduce Cancer's Spread - WebMD, 3/12/01 - "This study on mice shows that (injectable) heparin prevents platelets from sticking to the cancer cells, making them more vulnerable to the immune system's natural cleanup action"
• FDA Warns About Blood Thinner - Intelihealth, 3/6/01
• Drug dramatically cuts blood clot risk after surgery - USA Today, 2/28/01
• Once-Daily Blood Thinner, Enoxaparin, Effective In Treating Blood Clots - Doctor's Guide, 2/6/01
• FDA Approves Lovenox (Enoxaparin) For Prevention Of Blood Clots In Acutely Ill Patients - Doctor's Guide, 11/20/00
• Lovenox (Enoxaparin) And Aggrastat (Tirofiban) Well-Tolerated, Bleeding Rate Comparable To Heparin - Doctor's Guide, 11/15/00
• Anticoagulant Argatroban Available In The United States - Doctor's Guide, 11/13/00
• Innohep (Tinzaparin) Low Molecular Weight Heparin, Now Available In US - Doctor's Guide, 10/23/00
• Diabetics Undergoing Angioplasty Benefit From Antiplatelet Drug Reopro (Abciximab) - Doctor's Guide, 10/10/00
• Enoxaparin Safe For Use With IIb/IIIa Inhibitors - Doctor's Guide, 8/30/00
• Fragmin (Dalteparin)/Reopro (Abciximab) Combo Safe Treatment For Unstable Angina and Myocardial Infarctions - Doctor's Guide, 8/28/00
• Valsartan And Warfarin May Be Co-administered Safely - Doctor's Guide, 8/24/00
• FDA Approves Fragmin (Dalteparin) For Prevention Of Deep Vein Thrombosis Post-Op - Doctor's Guide, 8/7/00 - "showed that Fragmin administered in the post-operative period following hip replacement surgery was more effective than warfarin -- a standard treatment -- in preventing deep vein thrombosis"
• Fragmin (Dalteparin) More Effective Than Warfarin in Preventing Deep Vein Thrombosis - Doctor's Guide, 7/24/00
• FDA Approves Once-Daily Innohep (Tinzaparin) For Deep Vein Thrombosis - Doctor's Guide, 7/18/00
• Anti-Platelet Drug Cilostazol Shows Promise in Preventing Recurrent Stroke - Doctor's Guide, 7/18/00
• Many Herbal Remedies May Interact With Popular Blood Thinner - WebMD, 7/11/00
• At-Home Monitoring Works for People on Blood Thinners - WebMD, 7/7/00
• Under-use Of Blood Thinners Places Very Elderly At Risk For Stroke - Doctor's Guide, 7/4/00
• Argatroban Approved For Prevention Or Treatment Of Thrombosis In Heparin-Induced Thrombocytopenia - Doctor's Guide, 6/30/00
• Early Aspirin May Provide Quick Benefits For Acute Stroke Patients - Doctor's Guide, 6/1/00
• Clot-Busting Drugs: One Size Doesn't Fit All - WebMD, 5/15/00
• Treating Blood Clots at Home Made Easier With New Guidelines - Doctor's Guide, 5/9/00
• Subcutaneous low molecular weight heparin safe and cost-effective - Doctor's Guide, 5/5/00
• Fixed dosing more effective than variable dosing for patients requiring warfarin - Doctor's Guide, 5/3/00
• Blood-Thinning Drugs May Prevent Stroke In Elderly With Arrhythmias - Doctor's Guide, 4/7/00
• Study Shows Heparin No Better Than Aspirin For Some Stroke Patients - Intelihealth, 4/7/00
• Individual Drug Metabolism May Affect Drug Effectiveness, Cause Bleeding Problems - Doctor's Guide, 3/20/00
• Plavix (Clopidogrel) Superior To Aspirin For Preventing Acute Coronary Events - Doctor's Guide, 3/16/00
• Enoxaparin/rt-PA Combo Equivalent To Unfractionated Heparin/rt-PA For Heart Attack Patients - Doctor's Guide, 3/14/00
• Argatroban May Be Effective Replacement For Heparin - Doctor's Guide, 3/14/00
• Doctors' Dilemma: Knowing What Drugs To Recommend To Prevent Stroke - Doctor's Guide, 2/15/00
• Plavix Provides Benefits ASA Non-Responders - Doctor's Guide, 2/14/00
• Reviparin May Be Superior To Standard Heparin For Deep Vein Thrombosis - Doctor's Guide, 12/6/99
• Enoxaparin Beneficial In Patients With Increased Thromboembolic Risk - Doctor's Guide, 12/7/99
• Aspirin As Effective As Coumadin In Reducing Post-Heart Attack Risk - Doctor's Guide, 11/11/99
• Lovenox Helps Prevent Life-Threatening Blood Clots In Patients At Risk - Doctor's Guide, 11/10/99
• Low-Molecular-Weight Heparin Reduces Cardiac Events In UCAD Only When Serum Marker Is Positive - Doctor's Guide, 11/10/99
• Costs Reduced With Lovenox At Home Over Standard In-Hospital Treatment - Doctor's Guide, 10/25/99
• Prolonged Treatment of Deep Venous Thrombosis with Low-Molecular-Weight Heparin - Doctor's Guide, 10/12/99
• Tinzaparin Prevents Thromboembolic Events Better Than Unfractionated Heparin - Doctor's Guide, 10/5/99
• Low-Molecular-Weight Heparins Best For Certain Types of Heart Attack - Doctor's Guide, 9/29/99
• Enoxaparin Superior To Standard Unfractionated Heparin For Unstable CAD - Doctor's Guide, 8/13/99
• Safety, Activity Of Oral Heparin Comparable To Subcutaneous Form - Doctor's Guide, 8/20/99
• FDA Approves Fragmin For Unstable Angina And Non-Q-Wave MI - Doctor's Guide, 5/26/99
• FDA Approves Fragmin For Prevention Of Deep Vein Thrombosis - Doctor's Guide, 3/31/99
• Lovenox Superior To Heparin For Unstable Coronary Artery Disease - Doctor's Guide, 3/9/99 - "Rhone-Poulenc Rorer’s blood thinner Lovenox(R) (enoxaparin sodium) Injection should replace unfractionated heparin as the standard of care for the acute treatment of unstable angina (severe chest pain) and non-Q-wave myocardial infarction"
• Warfarin Underused In High-Risk Stroke Patients - Doctor's Guide, 10/20/98
• Treatment Of Irregular Heartbeat Prevents Stroke - Doctor's Guide, 9/3/98
• Plavix May Save Even More Lives In Actual Clinical Practice, Study Shows - Doctor's Guide, 8/26/98
• Enoxaparin May Help People Avoid Heart Attacks, Chest Pain - Doctor's Guide, 7/27/98
• Research Points to Better Blood Clotting Control - Doctor's Guide, 4/13/98
• Warfarin Continues To Be Underused As Stroke Preventive - Doctor's Guide, 4/9/98
• Prolonged Treatment With Fragmin Saves Lives - Doctor's Guide, 3/8/98
• Combining Acetaminophen With Anticoagulant Increases Risk Of Bleeding - Doctor's Guide, 3/3/98
• Aspirin Plus Warfarin Most Effective In Preventing Ischemic Heart Disease - Doctor's Guide, 1/23/98
• FDA Approves New Heart Attack And Stroke Drug [Plavix(R) (clopidogrel bisulfate)] - Doctor's Guide, 11/18/97
• Aspirin Alone Just As Beneficial As Aspirin And Warfarin After Heart Attack - Doctor's Guide, 8/8/97
• FDA Clears First Home Test for Blood Clotting - Doctor's Guide, 3/13/97
• New Heparin Allows Surgeons To Determine Dose Based On Patient's Weight - Doctor's Guide, 6/2/97
• Aspirin V Heparin For Stroke -- Aspirin Wins? - Doctor's Guide, 5/30/97
• ReoPro Prevents Angioplasty Complications Years After Single Treatment - Doctor's Guide, 8/26/96