QualityCounts.com
To address the growing use of ad blockers we now use affiliate links to sites like Amazon.com, streaming services, and others. Affiliate links help sites like QualityCounts.com stay open. Affiliate links cost you nothing but help me support my family. We do not allow paid reviews on this site. As an Amazon Associate I earn from qualifying purchases.  Also, you can donate  to ben@qualitycounts.com via Zelle or PayPal.  Click here for the PayPal QR.  Click here for Bitcoin QR code or Bitcoin address: 39muDw6WpQV8j6EdA8eUBvT5iFDiVpVpiE
Home ReliableRXPharmacy Past Newsletters Amazon.com Contact
 Sign-up for newsletter 
 Newsletter Archive
 Newsletter via RSS Feed
 Research on Supplements
 Health Conditions
 Anti-aging Recommendations
 Insulin and Aging
 QualityCounts.com in Time
 Longevity Affiliates:
 Amazon.com
 Coinbase
 

Home > Anti-aging Research > Betaine Hydrochloride.

Betaine Hydrochloride

Specific Recommendations:

News & Research:

Abstracts:

  • Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota - Food Funct 2022 Nov 24 - "The results showed that betaine greatly increased the body weight and decreased the disease activity index score of DSS-treated mice. Furthermore, betaine effectively downregulated the protein levels of pro-inflammatory cytokines (IL-1β, IL-6, and TNFα) and upregulated tight junction proteins (occludin and ZO-1) in the mice. Additionally, betaine exposure remarkably restricted the DSS-induced phosphorylation of IκB and NF-κB p65 in mice. Similarly, betaine pretreatment improved the inflammatory response and intestinal barrier of Caco-2 cells. Betaine altered the gut microbiota composition, markedly decreasing the relative abundance of Firmicutes and Proteobacteria and considerably increasing the relative abundance of Bacteroidota and Campylobacterota in DSS-induced mice. In conclusion, betaine could attenuate colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota and is conducive to developing new drugs for treating human diseases." - Note: I wish they would stop using betaine HCL and betaine anhydrous interchangably. My guess is that this study used betaine HCL (stomach acid). See betaine hydrochloride products at Amazon.com.
  • The effects of 14-week betaine supplementation on endocrine markers, body composition and anthropometrics in professional youth soccer players: a double blind, randomized, placebo-controlled trial - J Int Soc Sports Nutr 2021 Mar 4 - "Betaine supplementation may enhance body composition outcomes when supplemented chronically during an exercise program. The purpose of this study was to evaluate the effect of betaine supplementation on development-related hormones, body composition, and anthropometrics in professional youth soccer players during a competitive season ... Twenty-nine players (age, 15.45 ± 0.25 years) were matched based upon position and then randomly assigned to a betaine group (2 g/day; n = 14, BG) or placebo group ... testosterone to cortisol ratio (T/C) ... Betaine supplementation increased testosterone levels and T/C ratio in youth professional soccer players during a competitive season. Betaine supplementation had no negative effects on growth (height and weight) and may attenuate reductions in testosterone due to intense training during puberty" - Note:  I wish they would state whether it's betaine hydrochloride [HCl] or betaine anhydrous (trimethylglycine (TMG)).  It must be TMG because HCL is for digestion. - See betaine hydrochloride products at Amazon.com and betaine anhydrous (TMG) at Amazon.com.
    • Betaine HCl – Remembering the Basics - edu.emersonecologics.com - "Trimethylglycine (TMG) is a popular molecule in the betaine family – consisting of the amino acid glycine with three methyl groups attached. TMGs main uses are as either a primary (reducing homocysteine into L-methionine for cardio-protection) or secondary (affecting folate and SAMEe metabolism) methyl donor. For clarity it’s important to remember that the terms “TMG” and “betaine” are used interchangeably ... While still in the same molecular family, betaine hydrochloride [HCl] is a very different molecule. It is a protonated form of TMG, meaning it will give up or transfer a proton and a chloride ion in an aqueous solution (liquid). This makes betaine HCl a very good dietary source of hydrochloric or gastric acid"