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Home > Anti-aging Research > Betaine Hydrochloride.

Betaine Hydrochloride

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News & Research:


  • The effects of 14-week betaine supplementation on endocrine markers, body composition and anthropometrics in professional youth soccer players: a double blind, randomized, placebo-controlled trial - J Int Soc Sports Nutr 2021 Mar 4 - "Betaine supplementation may enhance body composition outcomes when supplemented chronically during an exercise program. The purpose of this study was to evaluate the effect of betaine supplementation on development-related hormones, body composition, and anthropometrics in professional youth soccer players during a competitive season ... Twenty-nine players (age, 15.45 ± 0.25 years) were matched based upon position and then randomly assigned to a betaine group (2 g/day; n = 14, BG) or placebo group ... testosterone to cortisol ratio (T/C) ... Betaine supplementation increased testosterone levels and T/C ratio in youth professional soccer players during a competitive season. Betaine supplementation had no negative effects on growth (height and weight) and may attenuate reductions in testosterone due to intense training during puberty" - Note:  I which they would state whether it's betaine hydrochloride [HCl] or betaine anhydrous (trimethylglycine (TMG)).  It must be TMG because HCL is for digestion. - See betaine hydrochloride products at Amazon.com and betaine anhydrous (TMG) at Amazon.com.
    • Betaine HCl – Remembering the Basics - edu.emersonecologics.com - "Trimethylglycine (TMG) is a popular molecule in the betaine family – consisting of the amino acid glycine with three methyl groups attached. TMGs main uses are as either a primary (reducing homocysteine into L-methionine for cardio-protection) or secondary (affecting folate and SAMEe metabolism) methyl donor. For clarity it’s important to remember that the terms “TMG” and “betaine” are used interchangeably ... While still in the same molecular family, betaine hydrochloride [HCl] is a very different molecule. It is a protonated form of TMG, meaning it will give up or transfer a proton and a chloride ion in an aqueous solution (liquid). This makes betaine HCl a very good dietary source of hydrochloric or gastric acid"