Recent Longevity News for the seven days ending 9/13/06.  You should consult your doctor if you are taking any medications.

Green Tea for Long Life? - WebMD, 9/12/06 - "Women who drink five or more 3.4-ounce cups of green tea every day cut their risk of heart disease by 31% compared with women who drink one or fewer 3.4-ounce cups. Men who drink this much green tea cut their heart disease risk by 22%" - See iHerb or Vitacost green tea extracts.

Vitamin D May Cut Pancreatic Cancer Risk By Nearly Half - Science Daily, 9/12/06 - "taking the U.S. Recommended Daily Allowance of Vitamin D (400 IU/day) reduced the risk of pancreatic cancer by 43 percent ... Vitamin D has shown strong potential for preventing and treating prostate cancer, and areas with greater sunlight exposure have lower incidence and mortality for prostate, breast, and colon cancers" - See iHerb or Vitacost vitamin D products.

Whole-grain diets may help reduce blood pressure - Reuters, 9/12/06 - "Blood pressure decreased significantly during the all whole-grain diets. Systolic blood pressure, the top reading, declined by 2.2 mm Hg when the subjects consumed the Step I diet and declined by an additional 1.4 to 6.7 mm Hg while subjects consumed the whole-grain diets"

Orange Juice Fights Kidney Stones - WebMD, 9/7/06 - "a daily glass of orange juice may help prevent recurrent kidney stones better than other citrus juices like lemonade"

Taking preventive medications curbs diabetes risk - Reuters, 9/7/06 - "Compared to patients who were adherent to placebo, those adherent to metformin had a 38.2 percent reduced risk of developing diabetes" - See metformin at OffshoreRx1.comor SuperSaverMeds.com (Glucophage)

NSAID Use May Prevent or Delay Development of Benign Prostate Hyperplasia - Medscape, 9/6/06 - "NSAIDs reduced the incidence rates of moderate-severe urinary symptoms (HR, 0.73), low maximum urinary flow rate (HR, 0 .51), increased prostate volume (HR, 0.53), elevated serum PSA level (HR, 0.52), and treatment of BPH (HR, 0.79)"

High Copper and Fat Intake Accelerates Cognitive Decline - Clinical Psychiatry News, 9/06 - "the increase in the rate of cognitive decline “for the high-fat consumers whose total copper intake was in the top 20% (more than 1.6 mg/day) was equivalent to 19 more years of age.” This is “an extraordinarily large estimate of effect"

Ginger/Feverfew Combo May Relieve Migraine - Clinical Psychiatry News, 9/06 - "Among 13 patients receiving GelStat Migraine, 8 reported headache relief after 2 hours, compared with 5 placebo patients, a statistically significant result"

Abstracts from this week's Doctor's Guide Nutrition/Dietetics:

Effect of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Type 1 Receptor Blockers on the Rate of New-Onset Diabetes Mellitus: A Review and Pooled Analysis - Pharmacotherapy. 2006 Sep;26(9):1297-306 - "The combined occurrence of new-onset diabetes in all 13 studies was 2249 cases among 31,283 patients (7.2%) in the ACE inhibitor or ARB group versus 3230 cases among 35,988 patients (9.0%) in the control group"

Green Tea Consumption and Mortality Due to Cardiovascular Disease, Cancer, and All Causes in Japan: The Ohsaki Study - JAMA, 9/13/06 - "Green tea consumption is associated with reduced mortality due to all causes and due to cardiovascular disease but not with reduced mortality due to cancer"

Rosiglitazone reduces microalbuminuria and blood pressure independently of glycemia in type 2 diabetes patients with microalbuminuria - J Hypertens. 2006 Oct;24(10):2047-2055 - "Rosiglitazone plus metformin reduced both mean 24-h systolic (-3.4 mmHg; P = 0.01) and diastolic (-2.5 mmHg; P < 0.01) ambulatory blood pressure compared with glyburide plus metformin"

Effects of n-3 fatty acids in subjects with type 2 diabetes: reduction of insulin sensitivity and time-dependent alteration from carbohydrate to fat oxidation - Am J Clin Nutr. 2006 Sep;84(3):540-50 - "Median intake in the intervention group was 17.6 mL fish oil/d (1.8 g 20:5n-3, 3.0 g 22:6n-3, and 5.9 g total n-3 fatty acids). The control group received 17.8 mL corn oil/d (8.5 g 18:2n-6) ... Glucose concentrations (home-monitored) were approximately 1 mmol/L higher in the fish oil group than in the corn oil group at the end of the intervention"

Adherence to Preventive Medications: Predictors and outcomes in the Diabetes Prevention Program - Diabetes Care. 2006 Sep;29(9):1997-2002 - "There was a 38.2% risk reduction for developing diabetes for those adherent to metformin compared with those adherent to placebo" - See metformin at OffshoreRx1.comor SuperSaverMeds.com (Glucophage).

The Age Related Decrease in Testosterone is Significantly Exacerbated in Obese Men With the Metabolic Syndrome. What are the Implications for the Relatively High Incidence of Erectile Dysfunction Observed in These Men? - J Urol. 2006 Oct;176(4):1524-8 - "testosterone decreased with increasing body mass index ... men with obesity and the metabolic syndrome have a significant decrease in total serum testosterone levels compared to aging, metabolically healthy men. These data suggest that the well established association between erectile dysfunction and pre-diabetes/diabetes (particularly in obese pre-diabetic/diabetic patients) may involve a hormonal component"

A Comparison of Lithium and T3 Augmentation Following Two Failed Medication Treatments for Depression: A STAR*D Report - Am J Psychiatry. 2006 Sep;163(9):1519-30 - "were randomly assigned to augmentation with lithium (up to 900 mg/day; N=69) or with T(3) (up to 50 mug/day; N=73) for up to 14 weeks ... After a mean of 9.6 weeks (SD=5.2) of treatment, remission rates were 15.9% with lithium augmentation and 24.7% with T(3) augmentation" - See T3 at International Anti-aging Systems.  Related study:

• T3 augmentation of SSRI resistant depression - J Affect Disord. 2006 Apr;91(2-3):211-5 - "The women took a mean daily dose of 40.6 mug of T3 for a mean duration of 3.75 weeks, while the men were on a mean daily dose of 43.8 mug of T3 for 3.5 weeks. T3 augmentation was associated with a statistically significant drop (p<.003) in the mean HAMD at end of the three weeks compared to baseline scores"

Influence of a single dose of 20 mg tadalafil, a phosphodiesterase 5 inhibitor, on ambulatory blood pressure in subjects with hypertension - Br J Clin Pharmacol. 2006 Sep;62(3):280-7 - "Overall tadalafil reduced mean ambulatory blood pressure monitor systolic and diastolic blood pressure by 4.8 mmHg [95% confidence interval (Cl) 3.7, 5.9; P < 0.01] and 2.9 mmHg (95% CI 1.9, 3.6; P < 0.01), respectively, compared with placebo. In hypertensive subjects with uncontrolled blood pressure on two to four classes of antihypertensive agents (n = 36) tadalafil reduced mean ABPM systolic and diastolic blood pressure by 7.5 mmHg (95% CI 5.4, 9.6; P < 0.01) and 4.3 mmHg (95% CI 6.1, 8.9; P < 0.01) compared with placebo"

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