Recent Longevity News for the seven days ending 4/7/04:

Low Vitamin B12 Is Associated With Poorer Memory In Older People With High Risk For Alzheimer's - Science Daily, 4/5/04 - "Among healthy people over the age of 75 who have the genotype associated with higher risk for Alzheimer's, low levels of vitamin B12 are associated with significantly worse performance on memory tests" - See iHerb B12 products.

Green tea action on leukaemia - Nutra USA, 4/1/04 - "The active component in green tea, epigallocatechin-3-gallate (EGCG), already shown to fight several types of cancer, also appears to kill cells of the most common form of leukaemia"

Updated Prostate Cancer Guidelines Recommend Lowering the PSA Threshold, Use of CPSA Test - Doctor's Guide, 4/1/04 - "studies of the incidence of cancer in men whose PSA is in the range of 2.5 to 4.0 ng/mL have shown that a substantial number of men in this group will have cancer"

Resveratrol, Powerful Protection Against Prostate Cancer - Life Extension Magazine, 4/04 - "Resveratrol works through more than a dozen different anticancer mechanisms and selectively targets cancer cells. This single supplement modulates hormones, has several mechanisms that stop cancer cells from multiplying, and even has the ability to destroy cancer cells" - See iHerb or Vitacost resveratrol products.

Memory enhancer named best new ingredient - Functional Foods and Nutraceuticals, 4/04 - "Citicoline is a form of choline that helps replenish the brain with phosphatidylserine ... In a double-blind trial of 84 elderly patients with mild to moderate memory loss, subjects who took 1000mg of citicoline daily for six weeks showed improvement in the acquisition of new information and its recall and improvement in global memory efficiency" - See iHerb or Vitacost citicoline products.

Evidence-based Products - Functional Foods and Nutraceuticals, 4/04 - "The first received Super CitriMax at 2,800mg HCA per day ... After eight weeks, the first group lost 6.2 per cent of body weight and reduced BMI by 6.3 per cent" - See Super CitriMax at iHerb.

CRP Test Little Help in Predicting Heart Risk - WebMD, 3/31/04 - "Now a much larger study shows that these studies overestimated the value of CRP tests .... The newer test adds little to what doctors already know about a person's heart-disease risk from blood cholesterol levels and smoking status"

Getting Some Sun May Fight Blood Cancer - WebMD, 3/31/04 - "women and men who got the most sun exposure during their off-work hours had the lowest risk of non-Hodgkin's lymphoma ... What might be causing it? The obvious answer is that vitamin D synthesized in the skin from sun exposure is causing this effect. There is increasing evidence that vitamin D has protective effects against many cancers. The evidence for colorectal cancer protection is pretty solid"

Abstracts from this week's Doctor's Guide Nutrition/Dietetics:

Farmed and wild fish in the prevention of cardiovascular diseases: assessing possible differences in lipid nutritional values - Nutr Metab Cardiovasc Dis. 2004 Feb;14(1):34-41 - "Provided that they are raised under appropriate conditions, the nutritional content of farmed fish is at least as beneficial as that of wild fish (particularly in terms of the prevention of cardiovascular diseases), and they also have the advantages of freshness and apparent non-toxicity" - That contradicts the following:

• Farm Salmon More Contaminated Than Wild - WebMD, 1/8/04 - "The most highly contaminated salmon came from farms in Europe, the study shows -- especially Scotland. North American and South American salmon farms had a lot less -- but still more than wild salmon"
• How Dangerous is Farmed Salmon? - Dr. Weil, 10/2/03 - "A study reported last year in the journal Chemosphere found the level of PCBs in farmed salmon in the U.S. and Canada to be five to 10 times higher than those in wild salmon"

Folate and colorectal neoplasia: relation between plasma and dietary markers of folate and adenoma recurrence - Am J Clin Nutr. 2004 Apr;79(4):691-697 - "A lower recurrence of colorectal adenomas was shown in subjects with higher intakes and plasma concentrations of folate. Additional markers involved in folate metabolism, including lower homocysteine and higher vitamin B-6 intake, were also associated with lower odds of recurrence"

LDL cholesterol-raising effect of low-dose docosahexaenoic acid in middle-aged men and women - Am J Clin Nutr. 2004 Apr;79(4):558-563 - "A daily intake of approximately 0.7 g DHA increases LDL cholesterol by 7% in middle-aged men and women. It is suggested that DHA down-regulates the expression of the LDL receptor"

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