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Home > Health Conditions > Tuberculosis

Tuberculosis

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  • Impact of N-Acetyl Cysteine (NAC) on Tuberculosis (TB) Patients-A Systematic Review - Antioxidants (Basel) 2022 Nov 21 - "Sustained TB infection overproduces reactive oxygen species (ROS) as a host defense mechanism. Research shows ROS is destructive to lung tissue. Glutathione (GSH) neutralizes ROS, although it is consumed. NAC is a precursor of GSH synthesis, and administering an appropriate dose of NAC to patients with respiratory conditions may enhance lung recovery and replenish GSH ... The use of NAC resulted in increased GSH levels, decreased treatment time, and was safe with minimal adverse events. However, the evidence is currently insufficient to estimate the overall effects of NAC, thus the study warrants more NAC clinical trials to demonstrate its effects in TB treatment" - See n-acetyl cysteine at Amazon.com.
  • Ginsenoside Rg1 Inhibits STAT3 Expression by miR-15b-5p to Attenuate Lung Injury in Mice with Type 2 Diabetes Mellitus-Associated Pulmonary Tuberculosis - Evid Based Complement Alternat Med 2022 Oct 4 - "Thus, we conclude that ginsenoside Rg1 inhibits the STAT3 expression by miR-15b-5p to attenuate lung injury in mice with type 2 diabetes mellitus-associated pulmonary tuberculosis" - See ginseng at Amazon.com.
  • Vitamin C can kill drug-resistant TB, researchers find - Science Daily, 5/21/13 - "vitamin C kills drug-resistant tuberculosis (TB) bacteria in laboratory culture. The finding suggests that vitamin C added to existing TB drugs could shorten TB therapy"
  • High doses of vitamin D help tuberculosis patients recover more quickly - Science Daily, 9/3/12 - "high doses of the vitamin Can dampen down the body's inflammatory response to infection, enabling patients to recover faster, with less damage to their lungs ... their results suggest that vitamin D supplementation might help patients recover better from other diseases such as pneumonia ... Mycobacterium tuberculosis, the bacterium that causes TB, was cleared from the patients' sputum (the phlegm coughed up from deep in the lungs) faster in those who were taking vitamin D, taking an average of 23 days to become undetectable under the microscope compared to 36 days in the patients who were taking the placebo" - See vitamin D at Amazon.com.
  • Vitamin D crucial in human immune response to tuberculosis, scientists find - Science Daily, 10/12/11 - "The team found that T cells, which are white blood cells that play a central role in immunity, release a protein called interferon-g that triggers communication between cells and directs infected immune cells to attack the invading tuberculosis bacteria. However, this activation requires sufficient levels of vitamin D to be effective ... Researchers next tested serum taken from blood samples in healthy humans, both with and without sufficient levels of vitamin D. They found that the immune response was not triggered in the serum with lower vitamin D levels, as is found in many African Americans. But, when adequate vitamin D was added to this deficient serum, the immune response was effectively activated ... vitamin D may help both innate and adaptive immunity, two systems that work synergistically together to fight infections" - See vitamin D at Amazon.com.
  • Vitamin D accelerates recovery from tuberculosis - Science Daily, 1/5/11 - "The average time to clearance of TB from the lungs among all study participants was 6 weeks for patients taking standard therapy alone and 5 weeks for those taking additional vitamin D, although this difference was not large enough to sustain statistical significance. However, patients who had a particular genetic type of vitamin D receptor were much more vitamin D responsive than others and cleared TB bacteria much more quickly if they received vitamin D in addition to standard antibiotic treatment" - See vitamin D at Amazon.com.
  • Common Vitamin And Other Micronutrient Supplements Reduce Risks Of TB Recurrence, Study Suggests - Science Daily, 4/25/08 - "micronutrients using doses of vitamins A, B-complex, C, E, and selenium or placebo ... both HIV-infected and uninfected patients with pulmonary TB who were receiving the supplements had a decreased risk of TB recurrence during the next few months after the TB culture had become negative: 45 percent overall and 63 percent in HIV-infected patients. Supplementation also reduced the incidence of peripheral neuropathy by 57 percent, irrespective of HIV status, and increased the levels of certain cells (CD3 and CD4) important in immune response in HIV-uninfected patients"
  • One Dose of Vitamin D Enhances Immunity to Mycobacteria - Medscape, 8/2/07 - "In healthy people who have been in contact with tuberculosis patients, a single oral dose of vitamin D enhances antimycobacterial immunity"
  • Vitamin D Supplements May Offer Cheap And Effective Immune System Boost Against TB - Science Daily, 5/14/07 - "a single 2.5mg dose of vitamin D may be enough to boost the immune system to fight against tuberculosis (TB) and similar bacteria for at least 6 weeks"
  • Catching and Curing TB? - Dr. Weil, 7/28/03

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